#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q0PHV7 uniprotkb:Q91ZD4 intact:EBI-6392520|ensembl:ENSMUSP00000104133 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393329|imex:IM-18117-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:004605A434608F99|rigid:becQD2CWkwg5xfw0UzqaRJC5Na0 false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:P63318 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392577|imex:IM-18117-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005 - - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090 intact-crc:F31A49D7D6934B3F|rigid:5FgvktqBY+nrQC3a7BvcEbe8Ylc false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:O09106 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394556|imex:IM-18117-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) - - - figure legend:6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 intact-crc:A3FB7EFB3EC610A6|rigid:T2o0ydXI/CV5lA/O35jPpUHB/kY false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P15806 uniprotkb:Q7TN08 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394510|imex:IM-18117-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:97ABF0B96DD878B0|rigid:0hiSat+iJItAq0k5gopd3ycb0eg false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P27782 uniprotkb:Q7TN08 intact:EBI-984464|ensembl:ENSMUSP00000029611 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:lef1_mouse(display_long)|uniprotkb:Lef1(gene name)|psi-mi:Lef1(display_short)|uniprotkb:Lef-1(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394456|imex:IM-18117-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001944"(vasculature development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021861"(forebrain radial glial cell differentiation)|ensembl:ENSMUST00000029611(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0021873"(forebrain neuroblast division)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0042100"(B cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048468"(cell development)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060033"(anatomical structure regression)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0061153"(trachea gland development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:0043586"(tongue development)|go:"GO:0043923"(positive regulation by host of viral transcription)|ensembl:ENSMUSG00000027985(gene)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028769|interpro:IPR036910|rcsb pdb:2LEF|rcsb pdb:3OUW|rcsb pdb:3OUX|reactome:R-MMU-201722|reactome:R-MMU-3769402|reactome:R-MMU-4086398|reactome:R-MMU-4641265|reactome:R-MMU-8853884|reactome:R-MMU-8951430|refseq:NP_034833.2|dip:DIP-35132N ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:clPGB7wopoDgQGcfPmc78dgSfxs10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:17D5C021CD8C14C3|rigid:sIkDdDc9di9GrA7RIHJAcQPgK8U false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q64729 uniprotkb:Q7TN08 intact:EBI-2899393|ensembl:ENSMUSP00000007757|uniprotkb:A2AJN0 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:tgfr1_mouse(display_long)|uniprotkb:Tgfbr1(gene name)|psi-mi:Tgfbr1(display_short)|uniprotkb:Transforming growth factor-beta receptor type I(gene name synonym)|uniprotkb:ESK2(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393345|imex:IM-18117-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000007613(gene)|ensembl:ENSMUST00000007757(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001824"(blastocyst development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005025"(transforming growth factor beta receptor activity, type I)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0007399"(nervous system development)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0007507"(heart development)|go:"GO:0005524"(ATP binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008584"(male gonad development)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016361"(activin receptor activity, type I)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048179"(activin receptor complex)|go:"GO:0048185"(activin binding)|go:"GO:0048538"(thymus development)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905007"(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:1905075"(positive regulation of tight junction disassembly)|go:"GO:1905223"(epicardium morphogenesis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q64729|reactome:R-MMU-2173788|reactome:R-MMU-2173789|reactome:R-MMU-2173791|reactome:R-MMU-5689880|refseq:NP_033396.1|refseq:NP_001299797.1|refseq:NP_001299798.1|dip:DIP-42262N ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:4E and F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:FVbLT2jZx3h9oz+W89A7vrzJLGY10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:8DBF26B81F09AED6|rigid:rn/I0G3bCO6MmT+uVMrhqW3I3ew false ha tag:?-?|mutation decreasing interaction:204-204 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91ZD4 uniprotkb:Q7TN08 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393321|imex:IM-18117-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:9DA0ADD5B4E7028D|rigid:0PA6qa0eeIcSDyZi2HbNgwjjtjk false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00417 uniprotkb:Q7TN08 intact:EBI-6394469 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:tcf7_mouse(display_long)|uniprotkb:Tcf7(gene name)|psi-mi:Tcf7(display_short)|uniprotkb:Tcf-1(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:T-cell-specific transcription factor 1(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394464|imex:IM-18117-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300910.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0021915"(neural tube development)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042492"(gamma-delta T cell differentiation)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|reactome:R-MMU-201722|reactome:R-MMU-3769402|reactome:R-MMU-4086398|reactome:R-MMU-4641265|reactome:R-MMU-8853884|reactome:R-MMU-8951430|go:"GO:0030538"(embryonic genitalia morphogenesis)|mint:Q00417|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|refseq:NP_033357.1|interpro:IPR028785|interpro:IPR027397|interpro:IPR036910 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:UmgdAeS+PUiRX80iBI1VGuTOM+c10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:624CE044CA51A426|rigid:8lxM6ubPiLwstOOWDLyWf+17FGI false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:Q60722 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-310070|uniprotkb:Q60721|uniprotkb:Q62211|uniprotkb:Q64072|uniprotkb:Q80UE8|ensembl:ENSMUSP00000077577|ensembl:ENSMUSP00000110631|ensembl:ENSMUSP00000110636 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:itf2_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)|uniprotkb:Itf2(gene name synonym)|uniprotkb:Sef2(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:Class A helix-loop-helix transcription factor ME2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394520|imex:IM-18117-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 refseq:NP_001077436.1|refseq:NP_038713.1|refseq:XP_006525809.1|refseq:XP_006525810.1|refseq:XP_006525813.1|refseq:XP_006525825.1|ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000078486(transcript)|ensembl:ENSMUST00000114980(transcript)|ensembl:ENSMUST00000114985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070888"(E-box binding)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:Q60722|reactome:R-MMU-525793|go:"GO:0016525"(negative regulation of angiogenesis)|refseq:XP_017173346.1|dip:DIP-42841N - - - figure legend:6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:o8X4UFFW9S6TNL/Ur0E/WC+b/8010090 intact-crc:4BC85CE4866F6918|rigid:VaZfbJbMWHD8slhUBOYa+ayuGFQ false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q0PHV7 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396850|imex:IM-18117-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:73C6EE1313E020F6|rigid:yJc2Q+d0F8kwx1OibH0jzvXgGmw false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q8R4A3 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396831|imex:IM-18117-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 - - - figure legend:7A, E and F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 intact-crc:67A3010CAB8FD528|rigid:sgR/SirLgwdxWA3My+fcsVVDcsM false ha tag:?-?|necessary binding region:85-149 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q91ZD4 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393313|imex:IM-18117-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:8A2235577A0158D6|rigid:yTcOG1pSd34vinJpB51F5HcKQkg false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63318 uniprotkb:Q0PHV7 intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392575|imex:IM-18117-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:2F90A9E797F71162|rigid:X9vewRt/5HFiTDwb15MuAnLl6QQ false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O09106 uniprotkb:Q7TN08 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394548|imex:IM-18117-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:8062FA68DD63BBB9|rigid:pFeaLsHVkKv0opBGlFULZLKL/kE false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q64729 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-2899393|ensembl:ENSMUSP00000007757|uniprotkb:A2AJN0 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:tgfr1_mouse(display_long)|uniprotkb:Tgfbr1(gene name)|psi-mi:Tgfbr1(display_short)|uniprotkb:Transforming growth factor-beta receptor type I(gene name synonym)|uniprotkb:ESK2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393337|imex:IM-18117-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 ensembl:ENSMUSG00000007613(gene)|ensembl:ENSMUST00000007757(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001824"(blastocyst development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005025"(transforming growth factor beta receptor activity, type I)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0007399"(nervous system development)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0007507"(heart development)|go:"GO:0005524"(ATP binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008584"(male gonad development)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016361"(activin receptor activity, type I)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048179"(activin receptor complex)|go:"GO:0048185"(activin binding)|go:"GO:0048538"(thymus development)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905007"(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:1905075"(positive regulation of tight junction disassembly)|go:"GO:1905223"(epicardium morphogenesis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q64729|reactome:R-MMU-2173788|reactome:R-MMU-2173789|reactome:R-MMU-2173791|reactome:R-MMU-5689880|refseq:NP_033396.1|refseq:NP_001299797.1|refseq:NP_001299798.1|dip:DIP-42262N - - - figure legend:4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:FVbLT2jZx3h9oz+W89A7vrzJLGY10090 intact-crc:9EB4BF37C29BD186|rigid:6/OBCucK63fP+bKLCghugCHAbFA false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:Q0PHV7 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396903|imex:IM-18117-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:B9480B97D1A9F031|rigid:KtT8d78Rwdrr8oUIwqI6Hnzz0Ro false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q7TN08 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396895|imex:IM-18117-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:53FE5E97DE5A6032|rigid:i7DUs6InYb1q7j7EFc5rZR/fDQI false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:Q7TN08 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396885|imex:IM-18117-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:7067DA043DFFCB2D|rigid:eHS9A1EBL2zx6RQmoQk9j0OLCFg false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63318 uniprotkb:Q7TN08 intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392579|imex:IM-18117-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:D083CD443536E020|rigid:QKS5wxLEl2TXfac15jcbEa1qhsY false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13547 uniprotkb:Q9NYF0-2 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-6394583|ensembl:ENSP00000378582 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:q9nyf0-2(display_long)|uniprotkb:Beta(isoform synonym)|uniprotkb:Short(isoform synonym)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394594|imex:IM-18117-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N ensembl:ENSG00000165617(gene)|ensembl:ENST00000395153(transcript)|intact:EBI-3951744(isoform-parent) - - - figure legend:6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:E15NhaPeqvfjg6+AOPMPdlU+u9k9606 intact-crc:3A80CEDFDE84F744|rigid:t27I9dK5/Dvk/cHM3TXFPopz7Iw false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13547 uniprotkb:Q9NYF0-1 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-6394566|ensembl:ENSP00000337439 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:q9nyf0-1(display_long)|uniprotkb:Alpha(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6394564|imex:IM-18117-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|intact:EBI-3951744(isoform-parent) - - - figure legend:6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606 intact-crc:EB5AED330FCF984D|rigid:1vuQzPHrPLgXksGxxiQaOz0/Yms false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q61062 uniprotkb:Q8R4A3 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392894|imex:IM-18117-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 intact-crc:3F7E998EDCFDA700|rigid:1YkZgC3Vp+ASlZebQHGb++XdDcY false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q61062 uniprotkb:Q0PHV7 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392946|imex:IM-18117-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:6465621F3E5F1F76|rigid:4Upurg+2YZBm/aoJXwOXe+RIeDM false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51141 uniprotkb:Q7TN08 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392686|imex:IM-18117-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:5FDFC3888F59DDB1|rigid:F8zPJwImkjcaO9wUlEZxt6G589g false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:O45030 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-869122|ensemblmetazoa:FBpp0087647 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:o45030_drome(display_long)|uniprotkb:Vang(gene name)|psi-mi:Vang(display_short)|uniprotkb:stbm(gene name synonym)|uniprotkb:CG8075(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393291|imex:IM-18117-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 flybase:FBgn0015838|dip:DIP-35779N|ensemblmetazoa:FBgn0015838(gene)|ensemblmetazoa:FBtr0088566(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005109"(frizzled binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR009539(Strabismus)|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728 - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:KK7iFNVimizORrJxiz5fcSV2f8c7227 intact-crc:3FEEF9A739B78C26|rigid:CIZ/7vUSriZcDHNEdvA9DqGiJrI false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0PHV7 uniprotkb:Q0PHV7 intact:EBI-6392520|ensembl:ENSMUSP00000104133 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396939|imex:IM-18117-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:C3826B8049CAA4FB|rigid:am3Mo/XJ98dk7Q8UQWNQB9kPYaU false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:P51140 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392902|imex:IM-18117-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 intact-crc:CC04375E994C761E|rigid:p9E51k2oP4sSvCYS4htVtO4vA/A false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q0PHV7 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396963|imex:IM-18117-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:1F088BB008AEFEA6|rigid:yJc2Q+d0F8kwx1OibH0jzvXgGmw false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q60838 uniprotkb:Q0PHV7 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392938|imex:IM-18117-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:9C25306ABEEC4805|rigid:ealqgpgoGmfDfHtiJwC80NFw2zY false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q80Z96 uniprotkb:Q0PHV7 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393275|imex:IM-18117-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:E62276B7DEE8E1E4|rigid:Ev9lG99e0BivBKXmSnqyyPGoZrg false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0PHV7 uniprotkb:Q7TN08 intact:EBI-6392520|ensembl:ENSMUSP00000104133 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396947|imex:IM-18117-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:3C910F23EB0B55B9|rigid:KtT8d78Rwdrr8oUIwqI6Hnzz0Ro false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51140 uniprotkb:Q7TN08 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392926|imex:IM-18117-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:EF9DB3CD7AE9DD01|rigid:D0jNsb1eIOaXETMLTFtAN0hVXl0 false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:Q60838 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392910|imex:IM-18117-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 intact-crc:5F9889206CB4908F|rigid:9i1bnt0YgluRkFTi2m6y8G5CV2Q false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0PHV7 uniprotkb:Q0PHV7 intact:EBI-6392520|ensembl:ENSMUSP00000104133 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6396955|imex:IM-18117-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:C3826A3049CAA4FB|rigid:am3Mo/XJ98dk7Q8UQWNQB9kPYaU false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51140 uniprotkb:Q0PHV7 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392954|imex:IM-18117-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:108ED76ED8282C43|rigid:gfEGkKK7AhywJG+xTWK8ziKEjSc false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:Q80Z96 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393267|imex:IM-18117-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:7BC4DEC65E6F6CF0|rigid:R+n/w7ciWQrItX7AhXHWuEW7rM4 false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q61062 uniprotkb:Q7TN08 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392918|imex:IM-18117-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:1CE71D1D3F580C1F|rigid:Xo6Bd/XCQ4HKe2IhPfV/STMhoKg false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q60838 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392719|imex:IM-18117-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 intact-crc:7C010DB38F113B90|rigid:dwjGglLyLmmr7eN5/nSHB9OXrjM false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O45030 uniprotkb:Q0PHV7 intact:EBI-869122|ensemblmetazoa:FBpp0087647 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:o45030_drome(display_long)|uniprotkb:Vang(gene name)|psi-mi:Vang(display_short)|uniprotkb:stbm(gene name synonym)|uniprotkb:CG8075(orf name) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393305|imex:IM-18117-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015838|dip:DIP-35779N|ensemblmetazoa:FBgn0015838(gene)|ensemblmetazoa:FBtr0088566(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005109"(frizzled binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR009539(Strabismus)|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:KK7iFNVimizORrJxiz5fcSV2f8c7227 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:C0FD9D049B767D64|rigid:GrLGJGqBUAfcR2rdIMKK+yHOoHU false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:O45030 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-869122|ensemblmetazoa:FBpp0087647 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:o45030_drome(display_long)|uniprotkb:Vang(gene name)|psi-mi:Vang(display_short)|uniprotkb:stbm(gene name synonym)|uniprotkb:CG8075(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393283|imex:IM-18117-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 flybase:FBgn0015838|dip:DIP-35779N|ensemblmetazoa:FBgn0015838(gene)|ensemblmetazoa:FBtr0088566(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005109"(frizzled binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR009539(Strabismus)|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728 - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:KK7iFNVimizORrJxiz5fcSV2f8c7227 intact-crc:1C777D34DA122739|rigid:dYIRA14+h19f2tNiykfY0YOkLy4 false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q80Z96 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393259|imex:IM-18117-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:E6E60C4889375963|rigid:8fbUPjNIjG/PE1pDAPW/I8tuRj8 false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51141 uniprotkb:Q0PHV7 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392688|imex:IM-18117-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:A0CCA72B2D982CF3|rigid:Y9PhTYQRIILSiE6uQDfvYZyh3Z4 false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51141 uniprotkb:Q8R4A3 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392684|imex:IM-18117-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 intact-crc:7C46471B6CFC76AE|rigid:3ByJmvGCFfjOueLWH487ARn0kc4 false ha tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:P49840 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-1044067|uniprotkb:O14959|ensembl:ENSP00000222330|ensembl:ENSP00000412663 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:gsk3a_human(display_long)|uniprotkb:GSK3A(gene name)|psi-mi:GSK3A(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392652|imex:IM-18117-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 ensembl:ENSG00000105723(gene)|ensembl:ENST00000222330(transcript)|ensembl:ENST00000453535(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010905"(negative regulation of UDP-glucose catabolic process)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071879"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904227"(negative regulation of glycogen synthase activity, transferring glucose-1-phosphate)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|mint:P49840|rcsb pdb:2DFM|reactome:R-HSA-198323|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|reactome:R-HSA-381038|reactome:R-HSA-5674400|reactome:R-HSA-9635465|reactome:R-HSA-9682706|reactome:R-HSA-9694686|refseq:NP_063937.2 - - - figure legend:2I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:CTNNFDhWycUTAOEW/KD2UXu0U7Y9606 intact-crc:669745F9FDB864D6|rigid:F9INgH5LEelPcPykc8W/cnRVPHQ false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0PHV7 uniprotkb:P30999 intact:EBI-6392520|ensembl:ENSMUSP00000104133 intact:EBI-529924|uniprotkb:Q3TSU9|uniprotkb:Q80XQ4|uniprotkb:Q8CHF8|ensembl:ENSMUSP00000064518|ensembl:ENSMUSP00000107320|ensembl:ENSMUSP00000141166 psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:ctnd1_mouse(display_long)|uniprotkb:Kiaa0384(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:Ctnnd1(gene name)|psi-mi:Ctnnd1(display_short)|uniprotkb:Catns(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393740|imex:IM-18117-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 refseq:NP_001078917.1|refseq:NP_001078918.1|refseq:NP_001078919.1|refseq:NP_001078922.1|refseq:NP_031641.2|refseq:XP_006498698.1|refseq:XP_017170690.1|refseq:XP_017170697.1|dip:DIP-31972N|ensembl:ENSMUSG00000034101(gene)|ensembl:ENSMUSG00000101645(gene)|ensembl:ENSMUST00000067232(transcript)|ensembl:ENSMUST00000111691(transcript)|ensembl:ENSMUST00000189772(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001822"(kidney development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060690"(epithelial cell differentiation involved in salivary gland development)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:P30999|reactome:R-MMU-418990|reactome:R-MMU-5218920 - - - figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 rogid:CvcAbgejB5iLlsSAxt47G/6W3P410090 intact-crc:9508D02BFD340313|rigid:ZKQW7TlbD1UTAvNRmiEwllwfJiU false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:Q9WV60 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-400793|ensembl:ENSMUSP00000023507 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392638|imex:IM-18117-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting) - - - figure legend:2H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090 intact-crc:38D3E6DF0A54E296|rigid:XxFuYnPh/cUuKWddltDN4UqVdmo false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9DC28 uniprotkb:Q7TN08 intact:EBI-6392453|ensembl:ENSMUSP00000018274|uniprotkb:Q3TZK2|uniprotkb:Q99KK4 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:kc1d_mouse(display_long)|uniprotkb:Csnk1d(gene name)|psi-mi:Csnk1d(display_short)|uniprotkb:Hckid(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392514|imex:IM-18117-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025162(gene)|ensembl:ENSMUST00000018274(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9DC28|rcsb pdb:4JJR|rcsb pdb:5X17|reactome:R-MMU-204005|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6791226|reactome:R-MMU-8854518|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|refseq:NP_620690.1|dip:DIP-47809N ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:FAsEbnos4akvB+YK6EAFbAsBtTo10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:37EC50771DD61B92|rigid:eQy4Y7KvG4rd1BDm/afrdrIYUaw false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:P30999 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-529924|uniprotkb:Q3TSU9|uniprotkb:Q80XQ4|uniprotkb:Q8CHF8|ensembl:ENSMUSP00000064518|ensembl:ENSMUSP00000107320|ensembl:ENSMUSP00000141166 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:ctnd1_mouse(display_long)|uniprotkb:Kiaa0384(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:Ctnnd1(gene name)|psi-mi:Ctnnd1(display_short)|uniprotkb:Catns(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393728|imex:IM-18117-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_001078917.1|refseq:NP_001078918.1|refseq:NP_001078919.1|refseq:NP_001078922.1|refseq:NP_031641.2|refseq:XP_006498698.1|refseq:XP_017170690.1|refseq:XP_017170697.1|dip:DIP-31972N|ensembl:ENSMUSG00000034101(gene)|ensembl:ENSMUSG00000101645(gene)|ensembl:ENSMUST00000067232(transcript)|ensembl:ENSMUST00000111691(transcript)|ensembl:ENSMUST00000189772(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001822"(kidney development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060690"(epithelial cell differentiation involved in salivary gland development)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:P30999|reactome:R-MMU-418990|reactome:R-MMU-5218920 - - - figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:CvcAbgejB5iLlsSAxt47G/6W3P410090 intact-crc:4E34901BBE70F94E|rigid:LoF5f8iv3Dk/jHWNiuFhxK/uXsE false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:P49840 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-1044067|uniprotkb:O14959|ensembl:ENSP00000222330|ensembl:ENSP00000412663 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:gsk3a_human(display_long)|uniprotkb:GSK3A(gene name)|psi-mi:GSK3A(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392658|imex:IM-18117-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 ensembl:ENSG00000105723(gene)|ensembl:ENST00000222330(transcript)|ensembl:ENST00000453535(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010905"(negative regulation of UDP-glucose catabolic process)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071879"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904227"(negative regulation of glycogen synthase activity, transferring glucose-1-phosphate)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|mint:P49840|rcsb pdb:2DFM|reactome:R-HSA-198323|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|reactome:R-HSA-381038|reactome:R-HSA-5674400|reactome:R-HSA-9635465|reactome:R-HSA-9682706|reactome:R-HSA-9694686|refseq:NP_063937.2 - - - figure legend:2I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:CTNNFDhWycUTAOEW/KD2UXu0U7Y9606 intact-crc:450EC16A1E1DCFC9|rigid:+TPi40Vw/v1B28IOMoS7TXvexAc false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0PHV7 uniprotkb:Q9DC28 intact:EBI-6392520|ensembl:ENSMUSP00000104133 intact:EBI-6392453|ensembl:ENSMUSP00000018274|uniprotkb:Q3TZK2|uniprotkb:Q99KK4 psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:kc1d_mouse(display_long)|uniprotkb:Csnk1d(gene name)|psi-mi:Csnk1d(display_short)|uniprotkb:Hckid(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392534|imex:IM-18117-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 ensembl:ENSMUSG00000025162(gene)|ensembl:ENSMUST00000018274(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9DC28|rcsb pdb:4JJR|rcsb pdb:5X17|reactome:R-MMU-204005|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6791226|reactome:R-MMU-8854518|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|refseq:NP_620690.1|dip:DIP-47809N - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 rogid:FAsEbnos4akvB+YK6EAFbAsBtTo10090 intact-crc:6D3993B3211AADE6|rigid:hd0GooplNQrI2nubCGu3rMikY4o false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:O35927 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-774108|uniprotkb:B2RR80 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:ctnd2_mouse(display_long)|uniprotkb:Neural plakophilin-related ARM-repeat protein(gene name synonym)|uniprotkb:Neurojungin(gene name synonym)|uniprotkb:Ctnnd2(gene name)|psi-mi:Ctnnd2(display_short)|uniprotkb:Catnd2(gene name synonym)|uniprotkb:Nprap(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393705|imex:IM-18117-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR028435|refseq:NP_032755.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|mint:O35927 - - - figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:/YXEXiU6UKZhK6McB762K0GKcN010090 intact-crc:9A0092CDFB99D7D8|rigid:NP82YUNsTwt/w7fP56tMmsiOpMk false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q60737 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392451|imex:IM-18117-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 - - - figure legend:2E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:E43D19736AF9C4DF|rigid:4aGd+TfXqUNjSazhyjs/ju+p3w4 false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O35927 uniprotkb:Q7TN08 intact:EBI-774108|uniprotkb:B2RR80 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:ctnd2_mouse(display_long)|uniprotkb:Neural plakophilin-related ARM-repeat protein(gene name synonym)|uniprotkb:Neurojungin(gene name synonym)|uniprotkb:Ctnnd2(gene name)|psi-mi:Ctnnd2(display_short)|uniprotkb:Catnd2(gene name synonym)|uniprotkb:Nprap(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393712|imex:IM-18117-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR028435|refseq:NP_032755.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|mint:O35927 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:/YXEXiU6UKZhK6McB762K0GKcN010090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:B999165E183C7CC7|rigid:kBDIty33/1/3iICRpIBL9C6geOU false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:P67871 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-348179|ensembl:ENSMUSP00000025246|ensembl:ENSMUSP00000134218|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q3TTJ7 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:csk2b_mouse(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Csnk2b(gene name)|psi-mi:Csnk2b(display_short)|uniprotkb:Ck2n(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392626|imex:IM-18117-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 ensembl:ENSMUSG00000024387(gene)|ensembl:ENSMUST00000025246(transcript)|ensembl:ENSMUST00000173114(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67871|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6798695|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751|refseq:NP_034105.1|refseq:NP_001290374.1|dip:DIP-35573N - - - figure legend:2G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg10090 intact-crc:3F41C54B9D00E445|rigid:mLB/n3NxjGJs5E5SeftNgXTp8uY false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TN08 uniprotkb:P30999 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 intact:EBI-529924|uniprotkb:Q3TSU9|uniprotkb:Q80XQ4|uniprotkb:Q8CHF8|ensembl:ENSMUSP00000064518|ensembl:ENSMUSP00000107320|ensembl:ENSMUSP00000141166 psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:ctnd1_mouse(display_long)|uniprotkb:Kiaa0384(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:Ctnnd1(gene name)|psi-mi:Ctnnd1(display_short)|uniprotkb:Catns(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393734|imex:IM-18117-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 refseq:NP_001078917.1|refseq:NP_001078918.1|refseq:NP_001078919.1|refseq:NP_001078922.1|refseq:NP_031641.2|refseq:XP_006498698.1|refseq:XP_017170690.1|refseq:XP_017170697.1|dip:DIP-31972N|ensembl:ENSMUSG00000034101(gene)|ensembl:ENSMUSG00000101645(gene)|ensembl:ENSMUST00000067232(transcript)|ensembl:ENSMUST00000111691(transcript)|ensembl:ENSMUST00000189772(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001822"(kidney development)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060690"(epithelial cell differentiation involved in salivary gland development)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:P30999|reactome:R-MMU-418990|reactome:R-MMU-5218920 - - - figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 rogid:CvcAbgejB5iLlsSAxt47G/6W3P410090 intact-crc:6DAD14885DD55251|rigid:0uJu9ciAYCu8YlYiLbKABNG4ymo false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:Q9WV60 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-400793|ensembl:ENSMUSP00000023507 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392644|imex:IM-18117-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting) - - - figure legend:2H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090 intact-crc:0325FB169C8FF2A4|rigid:SuM5QEL+VFmnfXWuGghWfdMeik4 false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P67871 uniprotkb:Q7TN08 intact:EBI-348179|ensembl:ENSMUSP00000025246|ensembl:ENSMUSP00000134218|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q3TTJ7 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:csk2b_mouse(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Csnk2b(gene name)|psi-mi:Csnk2b(display_short)|uniprotkb:Ck2n(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392632|imex:IM-18117-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024387(gene)|ensembl:ENSMUST00000025246(transcript)|ensembl:ENSMUST00000173114(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67871|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6798695|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751|refseq:NP_034105.1|refseq:NP_001290374.1|dip:DIP-35573N ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:2G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/16 2014/10/16 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:1CD841D87EA54F5A|rigid:k3vmzWVm7eIH6mD+howRaHBsh20 false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8R4A3 uniprotkb:O76324 intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943 intact:EBI-189923|uniprotkb:A4V3P5|uniprotkb:Q0KHY4|uniprotkb:Q9V462|ensemblmetazoa:FBpp0085104|ensemblmetazoa:FBpp0085105|ensemblmetazoa:FBpp0085106|ensemblmetazoa:FBpp0306615|ensemblmetazoa:FBpp0422974 psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym) psi-mi:dco_drome(display_long)|uniprotkb:dco(gene name)|psi-mi:dco(display_short)|uniprotkb:dbt(gene name synonym)|uniprotkb:Protein double-time(gene name synonym)|uniprotkb:CG2048(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392547|imex:IM-18117-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258 refseq:NP_524602.1|refseq:NP_733414.1|refseq:NP_733415.1|flybase:FBgn0002413|refseq:NP_001263132.1|dip:DIP-46048N|ensemblmetazoa:FBgn0002413(gene)|ensemblmetazoa:FBtr0085742(transcript)|ensemblmetazoa:FBtr0085743(transcript)|ensemblmetazoa:FBtr0085744(transcript)|ensemblmetazoa:FBtr0334548(transcript)|ensemblmetazoa:FBtr0473370(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007555"(regulation of ecdysteroid secretion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-390023|reactome:R-DME-390150|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090 rogid:ei2gU3lKLNgH3s2sv4AHRE7OM8Q7227 intact-crc:258BB89A486A7469|rigid:L7k4KffANJjaYbvJoqfM13ND9h0 false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02248 uniprotkb:Q7TN08 intact:EBI-397872|ensembl:ENSMUSP00000007130|ensembl:ENSMUSP00000136294|uniprotkb:Q922W1|uniprotkb:Q9D335 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:ctnb1_mouse(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:Ctnnb1(gene name)|psi-mi:Ctnnb1(display_short)|uniprotkb:Catnb(gene name synonym) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392551|imex:IM-18117-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048513"(animal organ development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|refseq:NP_001159374.1|refseq:NP_031640.1|ensembl:ENSMUSG00000006932(gene)|ensembl:ENSMUST00000007130(transcript)|ensembl:ENSMUST00000178812(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001706"(endoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001709"(cell fate determination)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001840"(neural plate development)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007507"(heart development)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009987"(cellular process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0022405"(hair cycle process)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034097"(response to cytokine)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043296"(apical junction complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044093"(positive regulation of molecular function)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|dip:DIP-31560N|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0060983"(epicardium-derived cardiac vascular smooth muscle cell differentiation)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072053"(renal inner medulla development)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072132"(mesenchyme morphogenesis)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904796"(regulation of core promoter binding)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:Q02248|rcsb pdb:1DOW|rcsb pdb:1I7W|rcsb pdb:1I7X|rcsb pdb:1JPP|rcsb pdb:1M1E|rcsb pdb:1V18|rcsb pdb:2BCT|rcsb pdb:3BCT|rcsb pdb:3OUW|rcsb pdb:3OUX|rcsb pdb:4EV8|rcsb pdb:4EV9|rcsb pdb:4EVA|rcsb pdb:4EVP|rcsb pdb:4EVT|rcsb pdb:4ONS|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-201681|reactome:R-MMU-201722|reactome:R-MMU-3134973|reactome:R-MMU-351906|reactome:R-MMU-3769402|reactome:R-MMU-4086398|reactome:R-MMU-418990|reactome:R-MMU-4641262|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467|reactome:R-MMU-8853884|reactome:R-MMU-8951430 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:xvyhb43JmWo6JgTE/YnFdAgvRlU10090 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:9E05C19618466DB6|rigid:vD480wir9zE3xjTqUuoR4Vqm3Dw false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02248 uniprotkb:Q0PHV7 intact:EBI-397872|ensembl:ENSMUSP00000007130|ensembl:ENSMUSP00000136294|uniprotkb:Q922W1|uniprotkb:Q9D335 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:ctnb1_mouse(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:Ctnnb1(gene name)|psi-mi:Ctnnb1(display_short)|uniprotkb:Catnb(gene name synonym) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393692|imex:IM-18117-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048513"(animal organ development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|refseq:NP_001159374.1|refseq:NP_031640.1|ensembl:ENSMUSG00000006932(gene)|ensembl:ENSMUST00000007130(transcript)|ensembl:ENSMUST00000178812(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001706"(endoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001709"(cell fate determination)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001840"(neural plate development)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007507"(heart development)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009987"(cellular process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0022405"(hair cycle process)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034097"(response to cytokine)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043296"(apical junction complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044093"(positive regulation of molecular function)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|dip:DIP-31560N|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0060983"(epicardium-derived cardiac vascular smooth muscle cell differentiation)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072053"(renal inner medulla development)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072132"(mesenchyme morphogenesis)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904796"(regulation of core promoter binding)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:Q02248|rcsb pdb:1DOW|rcsb pdb:1I7W|rcsb pdb:1I7X|rcsb pdb:1JPP|rcsb pdb:1M1E|rcsb pdb:1V18|rcsb pdb:2BCT|rcsb pdb:3BCT|rcsb pdb:3OUW|rcsb pdb:3OUX|rcsb pdb:4EV8|rcsb pdb:4EV9|rcsb pdb:4EVA|rcsb pdb:4EVP|rcsb pdb:4EVT|rcsb pdb:4ONS|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-201681|reactome:R-MMU-201722|reactome:R-MMU-3134973|reactome:R-MMU-351906|reactome:R-MMU-3769402|reactome:R-MMU-4086398|reactome:R-MMU-418990|reactome:R-MMU-4641262|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467|reactome:R-MMU-8853884|reactome:R-MMU-8951430 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:xvyhb43JmWo6JgTE/YnFdAgvRlU10090 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:6116A535BA879CF4|rigid:M/MrQNiPOFzqy84ntWtAVA4T8eQ false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O76324 uniprotkb:Q7TN08 intact:EBI-189923|uniprotkb:A4V3P5|uniprotkb:Q0KHY4|uniprotkb:Q9V462|ensemblmetazoa:FBpp0085104|ensemblmetazoa:FBpp0085105|ensemblmetazoa:FBpp0085106|ensemblmetazoa:FBpp0306615|ensemblmetazoa:FBpp0422974 intact:EBI-6392494|ensembl:ENSMUSP00000051638|uniprotkb:Q6PDF4|uniprotkb:Q8BHZ7 psi-mi:dco_drome(display_long)|uniprotkb:dco(gene name)|psi-mi:dco(display_short)|uniprotkb:dbt(gene name synonym)|uniprotkb:Protein double-time(gene name synonym)|uniprotkb:CG2048(orf name) psi-mi:dact2_mouse(display_long)|uniprotkb:Dact2(gene name)|psi-mi:Dact2(display_short)|uniprotkb:Dpr2(gene name synonym)|uniprotkb:Frd2(gene name synonym)|uniprotkb:Dapper antagonist of catenin 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6393698|imex:IM-18117-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524602.1|refseq:NP_733414.1|refseq:NP_733415.1|flybase:FBgn0002413|refseq:NP_001263132.1|dip:DIP-46048N|ensemblmetazoa:FBgn0002413(gene)|ensemblmetazoa:FBtr0085742(transcript)|ensemblmetazoa:FBtr0085743(transcript)|ensemblmetazoa:FBtr0085744(transcript)|ensemblmetazoa:FBtr0334548(transcript)|ensemblmetazoa:FBtr0473370(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007555"(regulation of ecdysteroid secretion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-390023|reactome:R-DME-390150|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 ensembl:ENSMUSG00000048826(gene)|ensembl:ENSMUST00000053218(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043588"(skin development)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:1900108"(negative regulation of nodal signaling pathway)|interpro:IPR024843|interpro:IPR024853|refseq:NP_766414.3 - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:ei2gU3lKLNgH3s2sv4AHRE7OM8Q7227 rogid:tt1Oj/TeJHBPLoxWzdoEeJgNaUo10090 intact-crc:06123C09ABCFDF76|rigid:vO7BmNdlXWKMMxwFngGOTyQCl/c false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O76324 uniprotkb:Q0PHV7 intact:EBI-189923|uniprotkb:A4V3P5|uniprotkb:Q0KHY4|uniprotkb:Q9V462|ensemblmetazoa:FBpp0085104|ensemblmetazoa:FBpp0085105|ensemblmetazoa:FBpp0085106|ensemblmetazoa:FBpp0306615|ensemblmetazoa:FBpp0422974 intact:EBI-6392520|ensembl:ENSMUSP00000104133 psi-mi:dco_drome(display_long)|uniprotkb:dco(gene name)|psi-mi:dco(display_short)|uniprotkb:dbt(gene name synonym)|uniprotkb:Protein double-time(gene name synonym)|uniprotkb:CG2048(orf name) psi-mi:dact3_mouse(display_long)|uniprotkb:Dact3(gene name)|psi-mi:Dact3(display_short)|uniprotkb:Dapper antagonist of catenin 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kivimae et al. (2011) pubmed:21718540|imex:IM-18117 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6392549|imex:IM-18117-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524602.1|refseq:NP_733414.1|refseq:NP_733415.1|flybase:FBgn0002413|refseq:NP_001263132.1|dip:DIP-46048N|ensemblmetazoa:FBgn0002413(gene)|ensemblmetazoa:FBtr0085742(transcript)|ensemblmetazoa:FBtr0085743(transcript)|ensemblmetazoa:FBtr0085744(transcript)|ensemblmetazoa:FBtr0334548(transcript)|ensemblmetazoa:FBtr0473370(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007555"(regulation of ecdysteroid secretion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-390023|reactome:R-DME-390150|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 ensembl:ENSMUSG00000078794(gene)|ensembl:ENSMUST00000108493(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR024843|interpro:IPR024844|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001075124.1 - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/11/16 2014/10/16 rogid:ei2gU3lKLNgH3s2sv4AHRE7OM8Q7227 rogid:ahyWBz7pNFjSrvChy598FQYw1SE10090 intact-crc:F90158AA090E2E34|rigid:PQn8YNsktPneLvuHM53kpQetNyM false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)