#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O50337 uniprotkb:Q04230 intact:EBI-6410783 intact:EBI-6410779 psi-mi:o50337_ecolx(display_long)|uniprotkb:trwE(gene name)|psi-mi:trwE(display_short) psi-mi:q04230_ecolx(display_long)|uniprotkb:trwB(gene name)|psi-mi:trwB(display_short) psi-mi:"MI:0014"(adenylate cyclase complementation) de et al. (2010) pubmed:20363945|imex:IM-18337 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6410775|mpidb:MPIDB-INT-1378|imex:IM-18337-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR005498(Bacterial conjugation TrbI-like protein)|interpro:IPR042217|refseq:YP_009182117.1|dip:DIP-60828N go:"GO:0000166"(nucleotide binding)|go:"GO:0000746"(conjugation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR014128(Type IV conjugative transfer system coupling protein TraD)|interpro:IPR019476|interpro:IPR027417|rcsb pdb:1E9R|rcsb pdb:1E9S|rcsb pdb:1GKI|rcsb pdb:1GL6|rcsb pdb:1GL7|refseq:YP_009182120.1|dip:DIP-16926N|refseq:WP_012196433.1 - - - figure legend:Table 5 Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:liqpT9GBvwgn2JkyB350hbMIytU562 rogid:UxI+kZMPO/XOzivemqofme+I9qA562 intact-crc:F92C512416A52AD1|rigid:HRLJFd9sWNaMQeZzv3Wkc51Gp+I false - sufficient binding region:1-75 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04230 uniprotkb:Q7X251 intact:EBI-6410779 intact:EBI-6416570 psi-mi:q04230_ecolx(display_long)|uniprotkb:trwB(gene name)|psi-mi:trwB(display_short) psi-mi:q7x251_9hyph(display_long)|uniprotkb:trwE(gene name)|psi-mi:trwE(display_short) psi-mi:"MI:0014"(adenylate cyclase complementation) de et al. (2010) pubmed:20363945|imex:IM-18337 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:85701(bartonella tribocoru)|taxid:85701(Bartonella tribocorum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6410940|mpidb:MPIDB-INT-1376|imex:IM-18337-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000166"(nucleotide binding)|go:"GO:0000746"(conjugation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR014128(Type IV conjugative transfer system coupling protein TraD)|interpro:IPR019476|interpro:IPR027417|rcsb pdb:1E9R|rcsb pdb:1E9S|rcsb pdb:1GKI|rcsb pdb:1GL6|rcsb pdb:1GL7|refseq:YP_009182120.1|dip:DIP-16926N|refseq:WP_012196433.1 go:"GO:0016021"(integral component of membrane)|refseq:WP_012232536.1|interpro:IPR005498(Bacterial conjugation TrbI-like protein)|interpro:IPR042217 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:UxI+kZMPO/XOzivemqofme+I9qA562 rogid:wHxo1yPA2r7vg9gROdUU2gdi7gc85701 intact-crc:1C852D106A28770A|rigid:d49yeyAVd5FvIsTM1KQDt3+QIsc false mutation increasing interaction strength:18-18|mutation increasing interaction strength:74-74|mutation increasing interaction strength:74-74,18-18 mutation increasing interaction strength:107-107|mutation increasing interaction strength:57-57|mutation increasing interaction strength:57-57|mutation increasing interaction strength:52-52 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04230 uniprotkb:Q04230 intact:EBI-6410779 intact:EBI-6410779 psi-mi:q04230_ecolx(display_long)|uniprotkb:trwB(gene name)|psi-mi:trwB(display_short) psi-mi:q04230_ecolx(display_long)|uniprotkb:trwB(gene name)|psi-mi:trwB(display_short) psi-mi:"MI:0014"(adenylate cyclase complementation) de et al. (2010) pubmed:20363945|imex:IM-18337 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6410998|mpidb:MPIDB-INT-1375|imex:IM-18337-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000166"(nucleotide binding)|go:"GO:0000746"(conjugation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR014128(Type IV conjugative transfer system coupling protein TraD)|interpro:IPR019476|interpro:IPR027417|rcsb pdb:1E9R|rcsb pdb:1E9S|rcsb pdb:1GKI|rcsb pdb:1GL6|rcsb pdb:1GL7|refseq:YP_009182120.1|dip:DIP-16926N|refseq:WP_012196433.1 go:"GO:0000166"(nucleotide binding)|go:"GO:0000746"(conjugation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR014128(Type IV conjugative transfer system coupling protein TraD)|interpro:IPR019476|interpro:IPR027417|rcsb pdb:1E9R|rcsb pdb:1E9S|rcsb pdb:1GKI|rcsb pdb:1GL6|rcsb pdb:1GL7|refseq:YP_009182120.1|dip:DIP-16926N|refseq:WP_012196433.1 - - - figure legend:Table 5, Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:UxI+kZMPO/XOzivemqofme+I9qA562 rogid:UxI+kZMPO/XOzivemqofme+I9qA562 intact-crc:6A84BA583E226574|rigid:7El2txb58ui+GrVDKiBgJ5X7LRc false mutation decreasing interaction strength:136-136|mutation increasing interaction strength:18-18|mutation increasing interaction strength:74-74|necessary binding region:1-12|mutation decreasing interaction strength:158-158 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04230 uniprotkb:Q04230 intact:EBI-6410779 intact:EBI-6410779 psi-mi:q04230_ecolx(display_long)|uniprotkb:trwB(gene name)|psi-mi:trwB(display_short) psi-mi:q04230_ecolx(display_long)|uniprotkb:trwB(gene name)|psi-mi:trwB(display_short) psi-mi:"MI:0014"(adenylate cyclase complementation) de et al. (2010) pubmed:20363945|imex:IM-18337 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6515990|imex:IM-18337-5|mpidb:MPIDB-INT-1375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000166"(nucleotide binding)|go:"GO:0000746"(conjugation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR014128(Type IV conjugative transfer system coupling protein TraD)|interpro:IPR019476|interpro:IPR027417|rcsb pdb:1E9R|rcsb pdb:1E9S|rcsb pdb:1GKI|rcsb pdb:1GL6|rcsb pdb:1GL7|refseq:YP_009182120.1|dip:DIP-16926N|refseq:WP_012196433.1 go:"GO:0000166"(nucleotide binding)|go:"GO:0000746"(conjugation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR014128(Type IV conjugative transfer system coupling protein TraD)|interpro:IPR019476|interpro:IPR027417|rcsb pdb:1E9R|rcsb pdb:1E9S|rcsb pdb:1GKI|rcsb pdb:1GL6|rcsb pdb:1GL7|refseq:YP_009182120.1|dip:DIP-16926N|refseq:WP_012196433.1 - - - figure legend:Table 5, Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:UxI+kZMPO/XOzivemqofme+I9qA562 rogid:UxI+kZMPO/XOzivemqofme+I9qA562 intact-crc:FEEF77FB9F023F57|rigid:7El2txb58ui+GrVDKiBgJ5X7LRc false mutation increasing interaction strength:18-18|mutation decreasing interaction strength:158-158|mutation decreasing interaction strength:136-136|necessary binding region:1-12|mutation increasing interaction strength:74-74 mutation decreasing interaction strength:136-136|necessary binding region:1-12|mutation decreasing interaction strength:158-158|mutation increasing interaction strength:18-18|mutation increasing interaction strength:74-74 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)