#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39060-PRO_0000005794 uniprotkb:P19338 intact:EBI-2566375|intact:EBI-9076876|intact:EBI-9028624 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:p39060-pro_0000005794(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fu et al. (2009) pubmed:19877579|imex:IM-17887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-6250913|imex:IM-17887-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-981314(chain-parent) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - chain-seq-start:1572|chain-seq-end:1754 - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/02/01 2014/10/16 rogid:/GEv8hNT/FBUcv637M4OgwJcP709606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:6336441E0A66EFE4|rigid:eSGyBzY4lkKm0sopl4jaWikkv78 false his tag:n-n|mutation disrupting interaction strength:139-139,27-27,53-53,24-24,62-63|mutation decreasing interaction strength:27-27,139-139|mutation decreasing interaction strength:24-24,53-53|mutation disrupting interaction strength:24-24,27-27,53-53,139-139|mutation decreasing interaction strength:62-62,63-63 his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P19338 uniprotkb:P39060-PRO_0000005794 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 intact:EBI-2566375|intact:EBI-9076876|intact:EBI-9028624 psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:p39060-pro_0000005794(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fu et al. (2009) pubmed:19877579|imex:IM-17887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-6254359|imex:IM-17887-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 intact:EBI-981314(chain-parent) - - chain-seq-start:1572|chain-seq-end:1754 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/02/01 2014/10/16 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 rogid:/GEv8hNT/FBUcv637M4OgwJcP709606 intact-crc:335BE3ADE00739F0 false his tag:n-n his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:28304" uniprotkb:P19338 intact:EBI-1379423 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fu et al. (2009) pubmed:19877579|imex:IM-17887 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-6254359|imex:IM-17887-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/02/01 2014/10/16 - rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:335BE3ADE00739F0 false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39060-PRO_0000005794 uniprotkb:P19338 intact:EBI-2566375|intact:EBI-9076876|intact:EBI-9028624 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:p39060-pro_0000005794(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Fu et al. (2009) pubmed:19877579|imex:IM-17887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-6254909|imex:IM-17887-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-981314(chain-parent) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - chain-seq-start:1572|chain-seq-end:1754 - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:7.01x10^-7(molar) 2012/02/01 2014/10/16 rogid:/GEv8hNT/FBUcv637M4OgwJcP709606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:14C5C6B3D16B208C|rigid:eSGyBzY4lkKm0sopl4jaWikkv78 false mutation decreasing interaction strength:27-27,139-139|mutation decreasing interaction strength:62-63|mutation disrupting interaction strength:24-24,27-27,53-53,139-139|mutation decreasing interaction strength:24-24,53-53|mutation decreasing interaction:24-24,27-27,53-53,62-62,139-139,63-63|his tag:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39060-PRO_0000005794 uniprotkb:P19338 intact:EBI-2566375|intact:EBI-9076876|intact:EBI-9028624 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:p39060-pro_0000005794(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Fu et al. (2009) pubmed:19877579|imex:IM-17887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0917"(matrixdb) intact:EBI-6250966|imex:IM-17887-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-981314(chain-parent) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - chain-seq-start:1572|chain-seq-end:1754 - figure legend:3A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/02/01 2014/10/16 rogid:/GEv8hNT/FBUcv637M4OgwJcP709606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:BDB7E42AEB700A3D|rigid:eSGyBzY4lkKm0sopl4jaWikkv78 false his tag:n-n - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P19338 uniprotkb:P39060-PRO_0000005794 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 intact:EBI-2566375|intact:EBI-9076876|intact:EBI-9028624 psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:p39060-pro_0000005794(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short) psi-mi:"MI:0051"(fluorescence technology) Fu et al. (2009) pubmed:19877579|imex:IM-17887 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0917"(matrixdb) intact:EBI-6254969|imex:IM-17887-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 intact:EBI-981314(chain-parent) - - chain-seq-start:1572|chain-seq-end:1754 figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/02/01 2014/10/16 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 rogid:/GEv8hNT/FBUcv637M4OgwJcP709606 intact-crc:A5F581391EE57BF4|rigid:eSGyBzY4lkKm0sopl4jaWikkv78 false his tag:n-n his tag:n-n|mutation decreasing interaction strength:53-53,24-24|mutation decreasing interaction strength:62-63|mutation decreasing interaction strength:27-27,139-139|mutation decreasing interaction strength:24-24,27-27,53-53,139-139|mutation disrupting interaction:24-24,27-27,53-53,62-62,63-63,139-139 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)