#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48763	uniprotkb:P61023	intact:EBI-6146620|uniprotkb:Q16434|ensembl:ENSRNOP00000021270	intact:EBI-917838|uniprotkb:Q62877|ensembl:ENSRNOP00000053243	psi-mi:sl9a2_rat(display_long)|uniprotkb:Slc9a2(gene name)|psi-mi:Slc9a2(display_short)|uniprotkb:Nhe2(gene name synonym)|uniprotkb:H7(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 2"(gene name synonym)|uniprotkb:Solute carrier family 9 member 2(gene name synonym)	psi-mi:chp1_rat(display_long)|uniprotkb:Chp1(gene name)|psi-mi:Chp1(display_short)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:Chp(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3719|refseq:NP_001106806.1|refseq:NP_036785.2|ensembl:ENSRNOG00000015567(gene)|ensembl:ENSRNOT00000021270(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0008104"(protein localization)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR001953("Na+/H+ exchanger, isoform 2 (NHE2)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR032103|reactome:R-RNO-425986	rgd:620447|refseq:NP_077053.1|ensembl:ENSRNOG00000004742(gene)|ensembl:ENSRNOT00000056405(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P61023|rcsb pdb:2CT9|reactome:R-RNO-2160916|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:2B, left|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:0KBoucm7kb7rjmJQx71bWmiEltg10116	rogid:xBd8WuYr8Uekzj+ou+oU5IiBcco10116	intact-crc:3A777FADA6E340BE|rigid:u1gXMVKn5mSbMF3+3jUdJ5gTLGE	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P26431	uniprotkb:P61023	intact:EBI-77471|ensembl:ENSRNOP00000011049	intact:EBI-917838|uniprotkb:Q62877|ensembl:ENSRNOP00000053243	psi-mi:sl9a1_rat(display_long)|uniprotkb:Slc9a1(gene name)|psi-mi:Slc9a1(display_short)|uniprotkb:Nhe1(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 1"(gene name synonym)|uniprotkb:Solute carrier family 9 member 1(gene name synonym)	psi-mi:chp1_rat(display_long)|uniprotkb:Chp1(gene name)|psi-mi:Chp1(display_short)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:Chp(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3718|refseq:NP_036784.1|ensembl:ENSRNOG00000007982(gene)|ensembl:ENSRNOT00000011049(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006885"(regulation of pH)|go:"GO:0009986"(cell surface)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0070997"(neuron death)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090533"(cation-transporting ATPase complex)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|interpro:IPR001970("Na+/H+ exchanger isoform 1 (NHE1)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR032103|reactome:R-RNO-2160916|reactome:R-RNO-425986	rgd:620447|refseq:NP_077053.1|ensembl:ENSRNOG00000004742(gene)|ensembl:ENSRNOT00000056405(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P61023|rcsb pdb:2CT9|reactome:R-RNO-2160916|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:2B, left|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:tvge6C3VxZPNUnTW2fCEZ40g5A010116	rogid:xBd8WuYr8Uekzj+ou+oU5IiBcco10116	intact-crc:2EA13566C809057C|rigid:4KUMJg54LwR3BOPs9EaiWeHU1k8	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q9Z0X2	uniprotkb:P61023	intact:EBI-6146676	intact:EBI-917838|uniprotkb:Q62877|ensembl:ENSRNOP00000053243	psi-mi:sl9a5_rat(display_long)|uniprotkb:Slc9a5(gene name)|psi-mi:Slc9a5(display_short)|uniprotkb:Nhe5(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 5"(gene name synonym)|uniprotkb:Solute carrier family 9 member 5(gene name synonym)	psi-mi:chp1_rat(display_long)|uniprotkb:Chp1(gene name)|psi-mi:Chp1(display_short)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:Chp(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620473|refseq:NP_620213.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:1902600"(proton transmembrane transport)	rgd:620447|refseq:NP_077053.1|ensembl:ENSRNOG00000004742(gene)|ensembl:ENSRNOT00000056405(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P61023|rcsb pdb:2CT9|reactome:R-RNO-2160916|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:2B, left|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:t6qm3C4kP6vHgPZpi1jDiPjdAXs10116	rogid:xBd8WuYr8Uekzj+ou+oU5IiBcco10116	intact-crc:4A34D0FCDDEB2822|rigid:X0lV2L6GzjSpON5rKPwSlUi9hww	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P26433	uniprotkb:P61023	intact:EBI-961694	intact:EBI-917838|uniprotkb:Q62877|ensembl:ENSRNOP00000053243	psi-mi:sl9a3_rat(display_long)|uniprotkb:Slc9a3(gene name)|psi-mi:Slc9a3(display_short)|uniprotkb:Nhe3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:chp1_rat(display_long)|uniprotkb:Chp1(gene name)|psi-mi:Chp1(display_short)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:Chp(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0031982"(vesicle)|rgd:3720|refseq:NP_036786.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986	rgd:620447|refseq:NP_077053.1|ensembl:ENSRNOG00000004742(gene)|ensembl:ENSRNOT00000056405(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P61023|rcsb pdb:2CT9|reactome:R-RNO-2160916|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:2B, left|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:7bSUDMNq7pX8lDlSPsoOAmVipD810116	rogid:xBd8WuYr8Uekzj+ou+oU5IiBcco10116	intact-crc:E83B5C6079EC3B54|rigid:jfx8BdVfbRCusUMTtnGVKa1fm2o	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P26434	uniprotkb:P61023	intact:EBI-6146651	intact:EBI-917838|uniprotkb:Q62877|ensembl:ENSRNOP00000053243	psi-mi:sl9a4_rat(display_long)|uniprotkb:Slc9a4(gene name)|psi-mi:Slc9a4(display_short)|uniprotkb:Nhe4(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 4"(gene name synonym)|uniprotkb:Solute carrier family 9 member 4(gene name synonym)	psi-mi:chp1_rat(display_long)|uniprotkb:Chp1(gene name)|psi-mi:Chp1(display_short)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:Chp(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032103|rgd:3721|refseq:NP_775121.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR001953("Na+/H+ exchanger, isoform 2 (NHE2)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986|interpro:IPR036958|go:"GO:0001696"(gastric acid secretion)|go:"GO:0002064"(epithelial cell development)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009651"(response to salt stress)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)	rgd:620447|refseq:NP_077053.1|ensembl:ENSRNOG00000004742(gene)|ensembl:ENSRNOT00000056405(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P61023|rcsb pdb:2CT9|reactome:R-RNO-2160916|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:2B, left|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:e881hL9FgNT3OnYo3lhUAm185Vc10116	rogid:xBd8WuYr8Uekzj+ou+oU5IiBcco10116	intact-crc:70D8D3E8F331E639|rigid:5qA2cQntZZktK4lKaaK2rxiKPjQ	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q810D1	uniprotkb:P48763	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-6146620|uniprotkb:Q16434|ensembl:ENSRNOP00000021270	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a2_rat(display_long)|uniprotkb:Slc9a2(gene name)|psi-mi:Slc9a2(display_short)|uniprotkb:Nhe2(gene name synonym)|uniprotkb:H7(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 2"(gene name synonym)|uniprotkb:Solute carrier family 9 member 2(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	rgd:3719|refseq:NP_001106806.1|refseq:NP_036785.2|ensembl:ENSRNOG00000015567(gene)|ensembl:ENSRNOT00000021270(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0008104"(protein localization)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR001953("Na+/H+ exchanger, isoform 2 (NHE2)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR032103|reactome:R-RNO-425986	-	-	-	figure legend:2B right|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:0KBoucm7kb7rjmJQx71bWmiEltg10116	intact-crc:C1E336BF324D2D0D|rigid:uSQfCxmf3l00oxVQlQHO9GK6ItQ	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q810D1	uniprotkb:P26433	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-961694	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a3_rat(display_long)|uniprotkb:Slc9a3(gene name)|psi-mi:Slc9a3(display_short)|uniprotkb:Nhe3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0031982"(vesicle)|rgd:3720|refseq:NP_036786.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986	-	-	-	figure legend:2B right|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:7bSUDMNq7pX8lDlSPsoOAmVipD810116	intact-crc:13AF1572ED4256E7|rigid:y+hw7t9Up3roc2XHM7Es5C24suo	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P26431	uniprotkb:Q810D1	intact:EBI-77471|ensembl:ENSRNOP00000011049	intact:EBI-6146708|ensembl:ENSRNOP00000025832	psi-mi:sl9a1_rat(display_long)|uniprotkb:Slc9a1(gene name)|psi-mi:Slc9a1(display_short)|uniprotkb:Nhe1(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 1"(gene name synonym)|uniprotkb:Solute carrier family 9 member 1(gene name synonym)	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3718|refseq:NP_036784.1|ensembl:ENSRNOG00000007982(gene)|ensembl:ENSRNOT00000011049(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006885"(regulation of pH)|go:"GO:0009986"(cell surface)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0070997"(neuron death)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090533"(cation-transporting ATPase complex)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|interpro:IPR001970("Na+/H+ exchanger isoform 1 (NHE1)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR032103|reactome:R-RNO-2160916|reactome:R-RNO-425986	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	-	-	-	figure legend:2A and 2B right|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:tvge6C3VxZPNUnTW2fCEZ40g5A010116	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	intact-crc:00B8FBAB20AA6899|rigid:uN+JoX2JsFJ3mzgjzw9kmtJpCsQ	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q810D1	uniprotkb:Q9Z0X2	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-6146676	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a5_rat(display_long)|uniprotkb:Slc9a5(gene name)|psi-mi:Slc9a5(display_short)|uniprotkb:Nhe5(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 5"(gene name synonym)|uniprotkb:Solute carrier family 9 member 5(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	rgd:620473|refseq:NP_620213.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:1902600"(proton transmembrane transport)	-	-	-	figure legend:2B right|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:t6qm3C4kP6vHgPZpi1jDiPjdAXs10116	intact-crc:75A230E0BF0F8E19|rigid:TFcPySJkvc1LILepTJGkzzQifxY	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q810D1	uniprotkb:P26434	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-6146651	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a4_rat(display_long)|uniprotkb:Slc9a4(gene name)|psi-mi:Slc9a4(display_short)|uniprotkb:Nhe4(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 4"(gene name synonym)|uniprotkb:Solute carrier family 9 member 4(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	interpro:IPR032103|rgd:3721|refseq:NP_775121.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR001953("Na+/H+ exchanger, isoform 2 (NHE2)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986|interpro:IPR036958|go:"GO:0001696"(gastric acid secretion)|go:"GO:0002064"(epithelial cell development)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009651"(response to salt stress)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)	-	-	-	figure legend:2B right|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:e881hL9FgNT3OnYo3lhUAm185Vc10116	intact-crc:8B4C9AFA679F8B8A|rigid:PcgV2Gdu1FpMbesvcy/sTlnkQXM	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q810D1	uniprotkb:P26431	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-77471|ensembl:ENSRNOP00000011049	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a1_rat(display_long)|uniprotkb:Slc9a1(gene name)|psi-mi:Slc9a1(display_short)|uniprotkb:Nhe1(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 1"(gene name synonym)|uniprotkb:Solute carrier family 9 member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	rgd:3718|refseq:NP_036784.1|ensembl:ENSRNOG00000007982(gene)|ensembl:ENSRNOT00000011049(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006885"(regulation of pH)|go:"GO:0009986"(cell surface)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0070997"(neuron death)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090533"(cation-transporting ATPase complex)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|interpro:IPR001970("Na+/H+ exchanger isoform 1 (NHE1)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR032103|reactome:R-RNO-2160916|reactome:R-RNO-425986	-	-	-	figure legend:2C|curation depth:mimix curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:tvge6C3VxZPNUnTW2fCEZ40g5A010116	intact-crc:CA245B10244B5C8F|rigid:uN+JoX2JsFJ3mzgjzw9kmtJpCsQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q810D1	uniprotkb:P26433	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-961694	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a3_rat(display_long)|uniprotkb:Slc9a3(gene name)|psi-mi:Slc9a3(display_short)|uniprotkb:Nhe3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6146765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0031982"(vesicle)|rgd:3720|refseq:NP_036786.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986	-	-	-	figure legend:2C|curation depth:mimix curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:7bSUDMNq7pX8lDlSPsoOAmVipD810116	intact-crc:2EB806A713509CCC|rigid:y+hw7t9Up3roc2XHM7Es5C24suo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q810D1	uniprotkb:P26433	intact:EBI-6146708|ensembl:ENSRNOP00000025832	intact:EBI-961694	psi-mi:chp2_rat(display_long)|uniprotkb:Chp2(gene name)|psi-mi:Chp2(display_short)	psi-mi:sl9a3_rat(display_long)|uniprotkb:Slc9a3(gene name)|psi-mi:Slc9a3(display_short)|uniprotkb:Nhe3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Inoue et al. (2003)	pubmed:12576672	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6160391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008757968.1|rgd:727796|refseq:NP_877402.1|refseq:XP_017444695.1|ensembl:ENSRNOG00000019112(gene)|ensembl:ENSRNOT00000025832(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015031"(protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247	go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0031982"(vesicle)|rgd:3720|refseq:NP_036786.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986	-	-	-	figure legend:6|curation depth:mimix curation	taxid:38605(didma-okp)|taxid:38605(Opossum kidney cell line)	-	2012/06/11	2014/10/16	rogid:+TDaEolbpjOvSult+PmApqvUW/c10116	rogid:7bSUDMNq7pX8lDlSPsoOAmVipD810116	intact-crc:6F31F0CE94A36C7C|rigid:y+hw7t9Up3roc2XHM7Es5C24suo	false	-	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)