#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P01275 uniprotkb:P01275 intact:EBI-7629173|ensembl:ENSP00000364647|ensembl:ENSP00000387662|uniprotkb:A6NN65|intact:MINT-8090511|uniprotkb:Q53TP6 intact:EBI-7629173|ensembl:ENSP00000364647|ensembl:ENSP00000387662|uniprotkb:A6NN65|intact:MINT-8090511|uniprotkb:Q53TP6 psi-mi:gluc_human(display_long)|uniprotkb:GCG(gene name)|psi-mi:GCG(display_short) psi-mi:gluc_human(display_long)|uniprotkb:GCG(gene name)|psi-mi:GCG(display_short) psi-mi:"MI:0016"(circular dichroism) Ghodke et al. (2012) pubmed:22212535|imex:IM-16803|mint:MINT-8299451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7629166|mint:MINT-8299667|imex:IM-16803-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-420092|reactome:R-HSA-422085|reactome:R-HSA-9660821|reactome:R-HSA-418555|ensembl:ENSG00000115263(gene)|ensembl:ENST00000375497(transcript)|ensembl:ENST00000418842(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0031767"(gastric inhibitory polypeptide receptor binding)|go:"GO:0031769"(glucagon receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|interpro:IPR000532(Glucagon/GIP/secretin/VIP)|interpro:IPR015550(Glucagon-like)|mint:P01275|rcsb pdb:1BH0|rcsb pdb:1D0R|rcsb pdb:1NAU|rcsb pdb:2G49|rcsb pdb:2L63|rcsb pdb:2L64|rcsb pdb:2M5P|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|rcsb pdb:2M5Q|rcsb pdb:3IOL|rcsb pdb:4APD|rcsb pdb:4ZGM|rcsb pdb:5OTU|rcsb pdb:5OTV|rcsb pdb:5OTW|rcsb pdb:5OTX|rcsb pdb:5VAI|rcsb pdb:5YQZ|rcsb pdb:6EDS|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6NZN|rcsb pdb:6PHI|rcsb pdb:6PHJ|rcsb pdb:6PHK|rcsb pdb:6PHL|rcsb pdb:6PHO|rcsb pdb:6PHP|rcsb pdb:6VCB|rcsb pdb:6X18|rcsb pdb:7D68|reactome:R-HSA-163359|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-416476|refseq:NP_002045.1|dip:DIP-46470N|mint:MINT-8299669(identity) reactome:R-HSA-420092|reactome:R-HSA-422085|reactome:R-HSA-9660821|reactome:R-HSA-418555|ensembl:ENSG00000115263(gene)|ensembl:ENST00000375497(transcript)|ensembl:ENST00000418842(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0031767"(gastric inhibitory polypeptide receptor binding)|go:"GO:0031769"(glucagon receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|interpro:IPR000532(Glucagon/GIP/secretin/VIP)|interpro:IPR015550(Glucagon-like)|mint:P01275|rcsb pdb:1BH0|rcsb pdb:1D0R|rcsb pdb:1NAU|rcsb pdb:2G49|rcsb pdb:2L63|rcsb pdb:2L64|rcsb pdb:2M5P|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|rcsb pdb:2M5Q|rcsb pdb:3IOL|rcsb pdb:4APD|rcsb pdb:4ZGM|rcsb pdb:5OTU|rcsb pdb:5OTV|rcsb pdb:5OTW|rcsb pdb:5OTX|rcsb pdb:5VAI|rcsb pdb:5YQZ|rcsb pdb:6EDS|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6NZN|rcsb pdb:6PHI|rcsb pdb:6PHJ|rcsb pdb:6PHK|rcsb pdb:6PHL|rcsb pdb:6PHO|rcsb pdb:6PHP|rcsb pdb:6VCB|rcsb pdb:6X18|rcsb pdb:7D68|reactome:R-HSA-163359|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-416476|refseq:NP_002045.1|dip:DIP-46470N|mint:MINT-8299670(identity) - comment:mint|comment:homomint comment:mint|comment:homomint comment:homomint|comment:mint|figure legend:f1 f2a t1 sf1 sf2 sf3 sf4 st1 st2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/19 2014/10/16 rogid:lZLjmf6wPVM15tLWwCJkDwY3CSw9606 rogid:lZLjmf6wPVM15tLWwCJkDwY3CSw9606 intact-crc:C9C726551BE53D6A|rigid:/g4gy7OGXBPbTreOmZcxDSC2UQo false binding-associated region:53-81(MINT-8299679) binding-associated region:53-81(MINT-8299675) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01275 uniprotkb:P01275 intact:EBI-7629173|ensembl:ENSP00000364647|ensembl:ENSP00000387662|uniprotkb:A6NN65|intact:MINT-8090511|uniprotkb:Q53TP6 intact:EBI-7629173|ensembl:ENSP00000364647|ensembl:ENSP00000387662|uniprotkb:A6NN65|intact:MINT-8090511|uniprotkb:Q53TP6 psi-mi:gluc_human(display_long)|uniprotkb:GCG(gene name)|psi-mi:GCG(display_short) psi-mi:gluc_human(display_long)|uniprotkb:GCG(gene name)|psi-mi:GCG(display_short) psi-mi:"MI:0051"(fluorescence technology) Ghodke et al. (2012) pubmed:22212535|imex:IM-16803|mint:MINT-8299451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7629242|mint:MINT-8299685|imex:IM-16803-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-420092|reactome:R-HSA-422085|reactome:R-HSA-9660821|reactome:R-HSA-418555|ensembl:ENSG00000115263(gene)|ensembl:ENST00000375497(transcript)|ensembl:ENST00000418842(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0031767"(gastric inhibitory polypeptide receptor binding)|go:"GO:0031769"(glucagon receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|interpro:IPR000532(Glucagon/GIP/secretin/VIP)|interpro:IPR015550(Glucagon-like)|mint:P01275|rcsb pdb:1BH0|rcsb pdb:1D0R|rcsb pdb:1NAU|rcsb pdb:2G49|rcsb pdb:2L63|rcsb pdb:2L64|rcsb pdb:2M5P|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|rcsb pdb:2M5Q|rcsb pdb:3IOL|rcsb pdb:4APD|rcsb pdb:4ZGM|rcsb pdb:5OTU|rcsb pdb:5OTV|rcsb pdb:5OTW|rcsb pdb:5OTX|rcsb pdb:5VAI|rcsb pdb:5YQZ|rcsb pdb:6EDS|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6NZN|rcsb pdb:6PHI|rcsb pdb:6PHJ|rcsb pdb:6PHK|rcsb pdb:6PHL|rcsb pdb:6PHO|rcsb pdb:6PHP|rcsb pdb:6VCB|rcsb pdb:6X18|rcsb pdb:7D68|reactome:R-HSA-163359|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-416476|refseq:NP_002045.1|dip:DIP-46470N|mint:MINT-8299691(identity) reactome:R-HSA-420092|reactome:R-HSA-422085|reactome:R-HSA-9660821|reactome:R-HSA-418555|ensembl:ENSG00000115263(gene)|ensembl:ENST00000375497(transcript)|ensembl:ENST00000418842(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0031767"(gastric inhibitory polypeptide receptor binding)|go:"GO:0031769"(glucagon receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|interpro:IPR000532(Glucagon/GIP/secretin/VIP)|interpro:IPR015550(Glucagon-like)|mint:P01275|rcsb pdb:1BH0|rcsb pdb:1D0R|rcsb pdb:1NAU|rcsb pdb:2G49|rcsb pdb:2L63|rcsb pdb:2L64|rcsb pdb:2M5P|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|rcsb pdb:2M5Q|rcsb pdb:3IOL|rcsb pdb:4APD|rcsb pdb:4ZGM|rcsb pdb:5OTU|rcsb pdb:5OTV|rcsb pdb:5OTW|rcsb pdb:5OTX|rcsb pdb:5VAI|rcsb pdb:5YQZ|rcsb pdb:6EDS|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6NZN|rcsb pdb:6PHI|rcsb pdb:6PHJ|rcsb pdb:6PHK|rcsb pdb:6PHL|rcsb pdb:6PHO|rcsb pdb:6PHP|rcsb pdb:6VCB|rcsb pdb:6X18|rcsb pdb:7D68|reactome:R-HSA-163359|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-416476|refseq:NP_002045.1|dip:DIP-46470N|mint:MINT-8299687(identity) - comment:mint|comment:homomint comment:mint|comment:homomint comment:homomint|comment:mint|figure legend:f2 t1 sf6 st2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/19 2014/10/16 rogid:lZLjmf6wPVM15tLWwCJkDwY3CSw9606 rogid:lZLjmf6wPVM15tLWwCJkDwY3CSw9606 intact-crc:B1BCD2713A0A7FEB|rigid:/g4gy7OGXBPbTreOmZcxDSC2UQo false binding-associated region:53-81(MINT-8299692) binding-associated region:53-81(MINT-8299688) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01275 uniprotkb:P01275 intact:EBI-7629173|ensembl:ENSP00000364647|ensembl:ENSP00000387662|uniprotkb:A6NN65|intact:MINT-8090511|uniprotkb:Q53TP6 intact:EBI-7629173|ensembl:ENSP00000364647|ensembl:ENSP00000387662|uniprotkb:A6NN65|intact:MINT-8090511|uniprotkb:Q53TP6 psi-mi:gluc_human(display_long)|uniprotkb:GCG(gene name)|psi-mi:GCG(display_short) psi-mi:gluc_human(display_long)|uniprotkb:GCG(gene name)|psi-mi:GCG(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Ghodke et al. (2012) pubmed:22212535|imex:IM-16803|mint:MINT-8299451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7629286|mint:MINT-8299703|imex:IM-16803-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-420092|reactome:R-HSA-422085|reactome:R-HSA-9660821|reactome:R-HSA-418555|ensembl:ENSG00000115263(gene)|ensembl:ENST00000375497(transcript)|ensembl:ENST00000418842(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0031767"(gastric inhibitory polypeptide receptor binding)|go:"GO:0031769"(glucagon receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|interpro:IPR000532(Glucagon/GIP/secretin/VIP)|interpro:IPR015550(Glucagon-like)|mint:P01275|rcsb pdb:1BH0|rcsb pdb:1D0R|rcsb pdb:1NAU|rcsb pdb:2G49|rcsb pdb:2L63|rcsb pdb:2L64|rcsb pdb:2M5P|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|rcsb pdb:2M5Q|rcsb pdb:3IOL|rcsb pdb:4APD|rcsb pdb:4ZGM|rcsb pdb:5OTU|rcsb pdb:5OTV|rcsb pdb:5OTW|rcsb pdb:5OTX|rcsb pdb:5VAI|rcsb pdb:5YQZ|rcsb pdb:6EDS|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6NZN|rcsb pdb:6PHI|rcsb pdb:6PHJ|rcsb pdb:6PHK|rcsb pdb:6PHL|rcsb pdb:6PHO|rcsb pdb:6PHP|rcsb pdb:6VCB|rcsb pdb:6X18|rcsb pdb:7D68|reactome:R-HSA-163359|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-416476|refseq:NP_002045.1|dip:DIP-46470N|mint:MINT-8299705(identity) reactome:R-HSA-420092|reactome:R-HSA-422085|reactome:R-HSA-9660821|reactome:R-HSA-418555|ensembl:ENSG00000115263(gene)|ensembl:ENST00000375497(transcript)|ensembl:ENST00000418842(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014823"(response to activity)|go:"GO:0031767"(gastric inhibitory polypeptide receptor binding)|go:"GO:0031769"(glucagon receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|interpro:IPR000532(Glucagon/GIP/secretin/VIP)|interpro:IPR015550(Glucagon-like)|mint:P01275|rcsb pdb:1BH0|rcsb pdb:1D0R|rcsb pdb:1NAU|rcsb pdb:2G49|rcsb pdb:2L63|rcsb pdb:2L64|rcsb pdb:2M5P|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|rcsb pdb:2M5Q|rcsb pdb:3IOL|rcsb pdb:4APD|rcsb pdb:4ZGM|rcsb pdb:5OTU|rcsb pdb:5OTV|rcsb pdb:5OTW|rcsb pdb:5OTX|rcsb pdb:5VAI|rcsb pdb:5YQZ|rcsb pdb:6EDS|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6NZN|rcsb pdb:6PHI|rcsb pdb:6PHJ|rcsb pdb:6PHK|rcsb pdb:6PHL|rcsb pdb:6PHO|rcsb pdb:6PHP|rcsb pdb:6VCB|rcsb pdb:6X18|rcsb pdb:7D68|reactome:R-HSA-163359|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-416476|refseq:NP_002045.1|dip:DIP-46470N|mint:MINT-8299709(identity) - comment:mint|comment:homomint comment:mint|comment:homomint comment:homomint|comment:mint|figure legend:f4 t1 sf5 st2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/12/19 2014/10/16 rogid:lZLjmf6wPVM15tLWwCJkDwY3CSw9606 rogid:lZLjmf6wPVM15tLWwCJkDwY3CSw9606 intact-crc:888F7F3D52B3D424|rigid:/g4gy7OGXBPbTreOmZcxDSC2UQo false binding-associated region:53-81(MINT-8299706) binding-associated region:53-81(MINT-8299710) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)