#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63092-2	uniprotkb:P42866	intact:EBI-7607528|ensembl:ENSP00000360136|uniprotkb:P04895-2|intact:MINT-4826723	intact:EBI-5282656|uniprotkb:Q60768|uniprotkb:A1XGX3|uniprotkb:A1XGX4|uniprotkb:A1YAC3|uniprotkb:A1YAC4|uniprotkb:A5H7G2|uniprotkb:Q4U2P4|uniprotkb:Q4U2Q6|uniprotkb:Q548C6|uniprotkb:Q6YC50|uniprotkb:Q8CAN5|uniprotkb:Q8CGW2|uniprotkb:Q8CH73|uniprotkb:Q8CH74|uniprotkb:Q8CH75|uniprotkb:Q8VBU3|uniprotkb:Q8VBU6|uniprotkb:Q8VBX8|uniprotkb:Q8VI69|uniprotkb:Q8VI70|uniprotkb:Q8VI71|uniprotkb:Q8VIN3|uniprotkb:Q8VIN4|uniprotkb:Q8VIN5|uniprotkb:Q8VIN6|uniprotkb:Q8VIP0|uniprotkb:Q8VIP1|uniprotkb:Q9JIY1|uniprotkb:Q9R0D1|uniprotkb:Q9R1L9|uniprotkb:Q9R1M0|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	psi-mi:p63092-2(display_long)|uniprotkb:GSP(gene name synonym)|uniprotkb:Alpha-S-short(isoform synonym)|uniprotkb:Alpha-S1(isoform synonym)|uniprotkb:GNASs(isoform synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS1(gene name synonym)	psi-mi:oprm_mouse(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Seyedabadi et al. (2012)	pubmed:22177524|imex:IM-16801|mint:MINT-8298930|mint:fj-11-0885.r1|doi:10.1111/j.1742-4658.2011.08459	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7607523|mint:MINT-8298938|imex:IM-16801-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087460(gene)|ensembl:ENST00000371095(transcript)|intact:EBI-1047114(isoform-parent)|uniprotkb:P63092-2(isoform-parent)|mint:MINT-8298940(identity)	refseq:NP_001291866.1|refseq:NP_001291867.1|refseq:NP_001291877.1|refseq:NP_001291879.1|refseq:NP_001291884.1|refseq:NP_001289722.1|refseq:NP_001289723.1|refseq:NP_001289724.1|refseq:NP_001289725.1|refseq:NP_001034741.1|refseq:XP_017169315.1|refseq:XP_017169316.1|dip:DIP-46148N|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4DKL|rcsb pdb:5C1M|rcsb pdb:6DDE|rcsb pdb:6DDF|reactome:R-MMU-111885|reactome:R-MMU-202040|reactome:R-MMU-375276|reactome:R-MMU-418594|mint:MINT-8298957(identity)	-	comment:mint	-	figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-s49)|taxid:10090(Mus musculus)	-	2011/12/15	2014/10/16	rogid:DGFroN8wVqG3lG1L6aRMY5bk+RM9606	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	intact-crc:B7B8AB7D941C5E27|rigid:Nf/OVyv5UbOdvGWLx+gEfqlXVeE	false	flag tag:?-?(MINT-8298980)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63092-2	uniprotkb:P42866	intact:EBI-7607528|ensembl:ENSP00000360136|uniprotkb:P04895-2|intact:MINT-4826723	intact:EBI-5282656|uniprotkb:Q60768|uniprotkb:A1XGX3|uniprotkb:A1XGX4|uniprotkb:A1YAC3|uniprotkb:A1YAC4|uniprotkb:A5H7G2|uniprotkb:Q4U2P4|uniprotkb:Q4U2Q6|uniprotkb:Q548C6|uniprotkb:Q6YC50|uniprotkb:Q8CAN5|uniprotkb:Q8CGW2|uniprotkb:Q8CH73|uniprotkb:Q8CH74|uniprotkb:Q8CH75|uniprotkb:Q8VBU3|uniprotkb:Q8VBU6|uniprotkb:Q8VBX8|uniprotkb:Q8VI69|uniprotkb:Q8VI70|uniprotkb:Q8VI71|uniprotkb:Q8VIN3|uniprotkb:Q8VIN4|uniprotkb:Q8VIN5|uniprotkb:Q8VIN6|uniprotkb:Q8VIP0|uniprotkb:Q8VIP1|uniprotkb:Q9JIY1|uniprotkb:Q9R0D1|uniprotkb:Q9R1L9|uniprotkb:Q9R1M0|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	psi-mi:p63092-2(display_long)|uniprotkb:GSP(gene name synonym)|uniprotkb:Alpha-S-short(isoform synonym)|uniprotkb:Alpha-S1(isoform synonym)|uniprotkb:GNASs(isoform synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS1(gene name synonym)	psi-mi:oprm_mouse(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Seyedabadi et al. (2012)	pubmed:22177524|imex:IM-16801|mint:MINT-8298930|mint:fj-11-0885.r1|doi:10.1111/j.1742-4658.2011.08459	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7607578|mint:MINT-8299007|imex:IM-16801-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087460(gene)|ensembl:ENST00000371095(transcript)|intact:EBI-1047114(isoform-parent)|uniprotkb:P63092-2(isoform-parent)|mint:MINT-8299009(identity)	refseq:NP_001291866.1|refseq:NP_001291867.1|refseq:NP_001291877.1|refseq:NP_001291879.1|refseq:NP_001291884.1|refseq:NP_001289722.1|refseq:NP_001289723.1|refseq:NP_001289724.1|refseq:NP_001289725.1|refseq:NP_001034741.1|refseq:XP_017169315.1|refseq:XP_017169316.1|dip:DIP-46148N|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4DKL|rcsb pdb:5C1M|rcsb pdb:6DDE|rcsb pdb:6DDF|reactome:R-MMU-111885|reactome:R-MMU-202040|reactome:R-MMU-375276|reactome:R-MMU-418594|mint:MINT-8299013(identity)	-	comment:mint	-	figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-s49)|taxid:10090(Mus musculus)	-	2011/12/15	2014/10/16	rogid:DGFroN8wVqG3lG1L6aRMY5bk+RM9606	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	intact-crc:3AF19F6A4A7E8133|rigid:Nf/OVyv5UbOdvGWLx+gEfqlXVeE	false	flag tag:?-?(MINT-8299010)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)