#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q07817 uniprotkb:Q07817 intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6 intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6 psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Ospina et al. (2011) pubmed:21856303|imex:IM-16778|mint:MINT-8203073|doi:10.1016/j.febslet.2011.08.012 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7083784|mint:MINT-8203078|imex:IM-16778-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N|mint:MINT-8203080(identity) refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N|mint:MINT-8203080(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" comment:mint|figure legend:f3a f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/09 2014/10/16 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 intact-crc:77A00EE7C9112386|rigid:WAsL/jZ2PMBkrPz6vArT5fb53Iw false tandem tag:?-?(MINT-8203082)|binding-associated region:204-233(MINT-8203085) tandem tag:?-?(MINT-8203082)|binding-associated region:204-233(MINT-8203085) 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63045 uniprotkb:P63045 intact:EBI-520880|uniprotkb:Q64357|intact:EBI-11701411|ensembl:ENSRNOP00000054114 intact:EBI-520880|uniprotkb:Q64357|intact:EBI-11701411|ensembl:ENSRNOP00000054114 psi-mi:vamp2_rat(display_long)|uniprotkb:Vamp2(gene name)|psi-mi:Vamp2(display_short)|uniprotkb:Syb2(gene name synonym)|uniprotkb:Synaptobrevin-2(gene name synonym) psi-mi:vamp2_rat(display_long)|uniprotkb:Vamp2(gene name)|psi-mi:Vamp2(display_short)|uniprotkb:Syb2(gene name synonym)|uniprotkb:Synaptobrevin-2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Ospina et al. (2011) pubmed:21856303|imex:IM-16778|mint:MINT-8203073|doi:10.1016/j.febslet.2011.08.012 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7083799|mint:MINT-8203088|imex:IM-16778-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3949|refseq:NP_036795.1|dip:DIP-35503N|ensembl:ENSRNOG00000006989(gene)|ensembl:ENSRNOT00000057295(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045202"(synapse)|go:"GO:0046879"(hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63045|rcsb pdb:1KIL|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:2BU0|rcsb pdb:2KOG|rcsb pdb:2N1T|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6A30|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-8856825|reactome:R-RNO-264642|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-449836|reactome:R-RNO-8856828|reactome:R-RNO-888590|reactome:R-RNO-9609523|mint:MINT-8203090(identity) rgd:3949|refseq:NP_036795.1|dip:DIP-35503N|ensembl:ENSRNOG00000006989(gene)|ensembl:ENSRNOT00000057295(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045202"(synapse)|go:"GO:0046879"(hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63045|rcsb pdb:1KIL|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:2BU0|rcsb pdb:2KOG|rcsb pdb:2N1T|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6A30|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-8856825|reactome:R-RNO-264642|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-449836|reactome:R-RNO-8856828|reactome:R-RNO-888590|reactome:R-RNO-9609523|mint:MINT-8203090(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" comment:mint|figure legend:f3a f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/08/09 2014/10/16 rogid:7XvjYTyMU62KV/BKEItoUAtIL5010116 rogid:7XvjYTyMU62KV/BKEItoUAtIL5010116 intact-crc:F693CD1E84489A7D|rigid:B7nBjQK4wwIZb8gz5Fw0wPLj3r0 false binding-associated region:84-115(MINT-8203091)|tandem tag:?-?(MINT-8203093) binding-associated region:84-115(MINT-8203091)|tandem tag:?-?(MINT-8203093) 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q07817 uniprotkb:Q07817 intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6 intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6 psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:"MI:0276"(blue native page) Ospina et al. (2011) pubmed:21856303|imex:IM-16778|mint:MINT-8203073|doi:10.1016/j.febslet.2011.08.012 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7083823|mint:MINT-8203104|imex:IM-16778-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N|mint:MINT-8203106(identity) refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N|mint:MINT-8203106(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:f3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/09 2014/10/16 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 intact-crc:477944FD21C9A5A5|rigid:WAsL/jZ2PMBkrPz6vArT5fb53Iw false tandem tag:?-?(MINT-8203109)|binding-associated region:204-233(MINT-8203107) tandem tag:?-?(MINT-8203109)|binding-associated region:204-233(MINT-8203107) 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63045 uniprotkb:P63045 intact:EBI-520880|uniprotkb:Q64357|intact:EBI-11701411|ensembl:ENSRNOP00000054114 intact:EBI-520880|uniprotkb:Q64357|intact:EBI-11701411|ensembl:ENSRNOP00000054114 psi-mi:vamp2_rat(display_long)|uniprotkb:Vamp2(gene name)|psi-mi:Vamp2(display_short)|uniprotkb:Syb2(gene name synonym)|uniprotkb:Synaptobrevin-2(gene name synonym) psi-mi:vamp2_rat(display_long)|uniprotkb:Vamp2(gene name)|psi-mi:Vamp2(display_short)|uniprotkb:Syb2(gene name synonym)|uniprotkb:Synaptobrevin-2(gene name synonym) psi-mi:"MI:0276"(blue native page) Ospina et al. (2011) pubmed:21856303|imex:IM-16778|mint:MINT-8203073|doi:10.1016/j.febslet.2011.08.012 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7083838|mint:MINT-8203128|imex:IM-16778-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3949|refseq:NP_036795.1|dip:DIP-35503N|ensembl:ENSRNOG00000006989(gene)|ensembl:ENSRNOT00000057295(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045202"(synapse)|go:"GO:0046879"(hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63045|rcsb pdb:1KIL|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:2BU0|rcsb pdb:2KOG|rcsb pdb:2N1T|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6A30|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-8856825|reactome:R-RNO-264642|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-449836|reactome:R-RNO-8856828|reactome:R-RNO-888590|reactome:R-RNO-9609523|mint:MINT-8203130(identity) rgd:3949|refseq:NP_036795.1|dip:DIP-35503N|ensembl:ENSRNOG00000006989(gene)|ensembl:ENSRNOT00000057295(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045202"(synapse)|go:"GO:0046879"(hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63045|rcsb pdb:1KIL|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:2BU0|rcsb pdb:2KOG|rcsb pdb:2N1T|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6A30|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-8856825|reactome:R-RNO-264642|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-449836|reactome:R-RNO-8856828|reactome:R-RNO-888590|reactome:R-RNO-9609523|mint:MINT-8203130(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:f3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/09 2014/10/16 rogid:7XvjYTyMU62KV/BKEItoUAtIL5010116 rogid:7XvjYTyMU62KV/BKEItoUAtIL5010116 intact-crc:E09307AFC3B3D2FA|rigid:B7nBjQK4wwIZb8gz5Fw0wPLj3r0 false binding-associated region:84-115(MINT-8203133)|tandem tag:?-?(MINT-8203131) binding-associated region:84-115(MINT-8203133)|tandem tag:?-?(MINT-8203131) 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)