#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11792 uniprotkb:Q12427 intact:EBI-16703|ensemblfungi:YHR205W|uniprotkb:D3DLF4 intact:EBI-34028|uniprotkb:D6VSE9|ensemblfungi:YDR169C psi-mi:sch9_yeast(display_long)|uniprotkb:YHR205W(locus name)|uniprotkb:SCH9(gene name)|psi-mi:SCH9(display_short)|uniprotkb:KOM1(gene name synonym) psi-mi:stb3_yeast(display_long)|uniprotkb:STB3(gene name)|psi-mi:STB3(display_short)|uniprotkb:YDR169C(locus name)|uniprotkb:YD9489.04c(orf name)|uniprotkb:SIN3-binding protein 3(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Huber et al. (2011) pubmed:21730963|imex:IM-16048|mint:MINT-8214170|doi:10.1038/emboj.2011.221 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7007253|mint:MINT-8214178|imex:IM-16048-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR205W(gene)|ensemblfungi:YHR205W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:1901494"(regulation of cysteine metabolic process)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|reactome:R-SCE-1257604|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0047484"(regulation of response to osmotic stress)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|reactome:R-SCE-1474151|reactome:R-SCE-165158|reactome:R-SCE-198693|reactome:R-SCE-199418|reactome:R-SCE-203615|reactome:R-SCE-389357|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-SCE-389513|reactome:R-SCE-392451|reactome:R-SCE-450385|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-6804758|reactome:R-SCE-6811558|reactome:R-SCE-9009391|reactome:R-SCE-9031628|refseq:NP_012075.1|sgd:S000001248|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR035892|mint:P11792|mint:MINT-8214180(identity) refseq:NP_010453.1|sgd:S000002576|mint:Q12427|dip:DIP-2486N|ensemblfungi:YDR169C(gene)|ensemblfungi:YDR169C_mRNA(transcript)|go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR018818|mint:MINT-8214181(identity) - - crc64:442B5633334B938F figure legend:f1d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/10/11 2014/10/16 rogid:GViiseOag6IGUlbTo1U/KAusk2I559292 rogid:B01Vwyu+/l7o9u4uzWRJppB0WjM559292 intact-crc:BD22E858C00B0C3C|rigid:bNvNXcjrF9JYzIR/rzG/ioNHpw4 false mutation increasing interaction:6-6(MINT-8214185) glutathione s tranferase tag:?-?(MINT-8214189) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P11792 uniprotkb:P40059 intact:EBI-16703|ensemblfungi:YHR205W|uniprotkb:D3DLF4 intact:EBI-6062|uniprotkb:D3DLZ5|ensemblfungi:YER088C psi-mi:sch9_yeast(display_long)|uniprotkb:YHR205W(locus name)|uniprotkb:SCH9(gene name)|psi-mi:SCH9(display_short)|uniprotkb:KOM1(gene name synonym) psi-mi:dot6_yeast(display_long)|uniprotkb:DOT6(gene name)|psi-mi:DOT6(display_short)|uniprotkb:PBF2(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 6(gene name synonym)|uniprotkb:PAC-binding factor 2(gene name synonym)|uniprotkb:YER088C(locus name) psi-mi:"MI:0424"(protein kinase assay) Huber et al. (2011) pubmed:21730963|imex:IM-16048|mint:MINT-8214170|doi:10.1038/emboj.2011.221 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7007293|mint:MINT-8214210|imex:IM-16048-4 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR205W(gene)|ensemblfungi:YHR205W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:1901494"(regulation of cysteine metabolic process)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|reactome:R-SCE-1257604|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0047484"(regulation of response to osmotic stress)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|reactome:R-SCE-1474151|reactome:R-SCE-165158|reactome:R-SCE-198693|reactome:R-SCE-199418|reactome:R-SCE-203615|reactome:R-SCE-389357|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-SCE-389513|reactome:R-SCE-392451|reactome:R-SCE-450385|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-6804758|reactome:R-SCE-6811558|reactome:R-SCE-9009391|reactome:R-SCE-9031628|refseq:NP_012075.1|sgd:S000001248|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR035892|mint:P11792|mint:MINT-8214212(identity) sgd:S000000890|refseq:NP_011012.3|dip:DIP-4823N|mint:P40059|ensemblfungi:YER088C(gene)|ensemblfungi:YER088C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|mint:MINT-8214216(identity) - - - figure legend:f1e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/10/11 2014/10/16 rogid:GViiseOag6IGUlbTo1U/KAusk2I559292 rogid:CLB1dDLYm9slfS2PCBGptkvD/os559292 intact-crc:6684586653C71FAD|rigid:LFkpeGHlqH+MpWsgGEBDthCEjKc false mutation increasing interaction:6-6(MINT-8214213) glutathione s tranferase tag:?-?(MINT-8214219)|mutation decreasing interaction:5-5(MINT-8214217) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P34219 uniprotkb:P11792 intact:EBI-3679833|uniprotkb:D6VPU6|ensemblfungi:YBL054W intact:EBI-16703|ensemblfungi:YHR205W|uniprotkb:D3DLF4 psi-mi:tod6_yeast(display_long)|uniprotkb:TOD6(gene name)|psi-mi:TOD6(display_short)|uniprotkb:PBF1(gene name synonym)|uniprotkb:PAC-binding factor 1(gene name synonym)|uniprotkb:Twin of DOT6(gene name synonym)|uniprotkb:YBL0513(orf name)|uniprotkb:YBL0509(orf name)|uniprotkb:YBL054W(locus name) psi-mi:sch9_yeast(display_long)|uniprotkb:YHR205W(locus name)|uniprotkb:SCH9(gene name)|psi-mi:SCH9(display_short)|uniprotkb:KOM1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Huber et al. (2011) pubmed:21730963|imex:IM-16048|mint:MINT-8214170|doi:10.1038/emboj.2011.221 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7007271|mint:MINT-8214193|imex:IM-16048-3 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P34219|refseq:NP_009499.1|sgd:S000000150|dip:DIP-2636N|ensemblfungi:YBL054W(gene)|ensemblfungi:YBL054W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|mint:MINT-8214199(identity) ensemblfungi:YHR205W(gene)|ensemblfungi:YHR205W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:1901494"(regulation of cysteine metabolic process)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|reactome:R-SCE-1257604|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0047484"(regulation of response to osmotic stress)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|reactome:R-SCE-1474151|reactome:R-SCE-165158|reactome:R-SCE-198693|reactome:R-SCE-199418|reactome:R-SCE-203615|reactome:R-SCE-389357|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-SCE-389513|reactome:R-SCE-392451|reactome:R-SCE-450385|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-6804758|reactome:R-SCE-6811558|reactome:R-SCE-9009391|reactome:R-SCE-9031628|refseq:NP_012075.1|sgd:S000001248|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR035892|mint:P11792|mint:MINT-8214195(identity) - - - comment:mint|figure legend:f1f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/10/11 2014/10/16 rogid:PlBnmLUZntyaAa7SvLmOGGuHKVk559292 rogid:GViiseOag6IGUlbTo1U/KAusk2I559292 intact-crc:1A348BEE2E0F67D9|rigid:o4Um9cO2a5XIjF/9JIew3C3xZ0Q false mutation decreasing interaction:6-6(MINT-8214206)|glutathione s tranferase tag:?-?(MINT-8214200) mutation increasing interaction:6-6(MINT-8214196) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q12427 uniprotkb:P40505 intact:EBI-34028|uniprotkb:D6VSE9|ensemblfungi:YDR169C intact:EBI-16809|ensemblfungi:YIL084C|uniprotkb:D6VVK2 psi-mi:stb3_yeast(display_long)|uniprotkb:STB3(gene name)|psi-mi:STB3(display_short)|uniprotkb:YDR169C(locus name)|uniprotkb:YD9489.04c(orf name)|uniprotkb:SIN3-binding protein 3(gene name synonym) psi-mi:sds3_yeast(display_long)|uniprotkb:YIL084C(locus name)|uniprotkb:SDS3(gene name)|psi-mi:SDS3(display_short)|uniprotkb:Suppressor of defective silencing protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Huber et al. (2011) pubmed:21730963|imex:IM-16048|mint:MINT-8214170|doi:10.1038/emboj.2011.221 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7007324|mint:MINT-8214229|imex:IM-16048-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010453.1|sgd:S000002576|mint:Q12427|dip:DIP-2486N|ensemblfungi:YDR169C(gene)|ensemblfungi:YDR169C_mRNA(transcript)|go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR018818|mint:MINT-8214235(identity) ensemblfungi:YIL084C(gene)|ensemblfungi:YIL084C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0016575"(histone deacetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070822"(Sin3-type complex)|go:"GO:2000217"(regulation of invasive growth in response to glucose limitation)|interpro:IPR013907(Sds3-like)|reactome:R-SCE-3214815|refseq:NP_012182.1|sgd:S000001346|dip:DIP-2706N|mint:P40505|mint:MINT-8214231(identity) - crc64:442B5633334B938F crc64:4A6186E68BFE0CC7 comment:mint|figure legend:sf8a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/10/11 2014/10/16 rogid:B01Vwyu+/l7o9u4uzWRJppB0WjM559292 rogid:Ri0JEWQXqBHUb95AnRdMYEkSz+Y559292 intact-crc:CFBFFDED135CC087|rigid:2XC7vA9puUgNlPUhgbJe19XNmGQ false calmodulin binding peptide plus protein a tag:?-?(MINT-8214236) ha tag:?-?(MINT-8214240) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)