#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60543 uniprotkb:P55055 intact:EBI-718966|uniprotkb:B0YIY7|uniprotkb:Q6UPR7|ensembl:ENSP00000320209 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 psi-mi:cidea_human(display_long)|uniprotkb:Cell death-inducing DFFA-like effector A(gene name synonym)|uniprotkb:CIDEA(gene name)|psi-mi:CIDEA(display_short) psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0096"(pull down) Kulyte et al. (2011) pubmed:21315073|imex:IM-17265|mint:MINT-8089866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1263"(Molecular Connections) intact:EBI-3865184|imex:IM-17265-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001270.1|ensembl:ENSG00000176194(gene)|ensembl:ENST00000320477(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0019915"(lipid storage)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0070417"(cellular response to cold)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR032936|rcsb pdb:2EEL|reactome:R-HSA-8964572 refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N - - - figure legend:fig. 2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/31 2014/10/16 rogid:Vkna6VNoCb/MGZBNpHwmpoOk2Ic9606 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 intact-crc:9FCDF05C7629C88E|rigid:aXL+EvRMzfR3ceKoYjY/3iJlXKg false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)