#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UGP8 uniprotkb:Q6DKJ4 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 intact:EBI-1055389|uniprotkb:Q3SWW6|uniprotkb:Q6P3U6|uniprotkb:Q9H9Q1|uniprotkb:B4DXQ0|uniprotkb:Q7L4C6|uniprotkb:D3DTH2|ensembl:ENSP00000337443 psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:nxn_human(display_long)|uniprotkb:NXN(gene name)|psi-mi:NXN(display_short)|uniprotkb:NRX(gene name synonym) psi-mi:"MI:0018"(two hybrid) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8566450|mint:MINT-8085420 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085423(identity) refseq:NP_071908.2|refseq:NP_001192248.1|ensembl:ENST00000336868(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:Q6DKJ4|ensembl:ENSG00000167693(gene)|mint:MINT-8085422(identity) - - - figure legend:f1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/01/12 2014/10/16 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 rogid:xQsuChT9r8OMThUdFAfhMknlhzU9606 intact-crc:E0203017A39191B2|rigid:J9qAqWzu4QFHwooQvfBF6aUPdtQ false binding-associated region:210-760(MINT-8085434)|fusion protein:?-?(MINT-8085431) binding-associated region:411-435(MINT-8085428)|fusion protein:?-?(MINT-8085425) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UGP8 uniprotkb:P97346 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:"MI:0096"(pull down) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8566481|mint:MINT-8085437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085445(identity) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-8085439(identity) - - - figure legend:f2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/12 2014/10/16 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 intact-crc:C28EDA58EACEEAC4|rigid:oOGdNlz2EefzBsPotuf+/EAcmjs false binding-associated region:210-733(MINT-8085446)|glutathione s tranferase tag:?-?(MINT-8085448) his tag:?-?(MINT-8085442) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P97346 uniprotkb:Q9UGP8 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:"MI:0081"(peptide array) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8566538|mint:MINT-8085485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-8085491(identity) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085487(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/12 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 intact-crc:7C463AB4715ED6C6|rigid:oOGdNlz2EefzBsPotuf+/EAcmjs false - binding-associated region:495-559(MINT-8085488) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q9UGP8 uniprotkb:P97346 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:"MI:0081"(peptide array) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8566524|mint:MINT-8085475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085477(identity) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-8085481(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/12 2014/10/16 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 intact-crc:2EA8ECE2132885AF|rigid:oOGdNlz2EefzBsPotuf+/EAcmjs false binding-associated region:370-414(MINT-8085478) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P97346 uniprotkb:Q9UGP8 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:"MI:0081"(peptide array) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8566510|mint:MINT-8085456 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-8085464(identity) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085458(identity) - - - comment:homomint|comment:mint|figure legend:f3c f3d taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/12 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 intact-crc:6C71ACD021477062|rigid:oOGdNlz2EefzBsPotuf+/EAcmjs false - binding-associated region:275-319(MINT-8085461) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P97346 uniprotkb:Q9UGP8 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:"MI:0081"(peptide array) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8566552|mint:MINT-8085496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-8085502(identity) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085498(identity) - - - comment:homomint|comment:mint|figure legend:f3a f3b taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/12 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 intact-crc:93733D55178BB5AD|rigid:oOGdNlz2EefzBsPotuf+/EAcmjs false binding-associated region:105-135(MINT-8085506) glutathione s tranferase tag:?-?(MINT-8085509)|binding-associated region:509-630(MINT-8085499) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P97346 uniprotkb:Q9UGP8 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym) psi-mi:"MI:0081"(peptide array) Müller et al. (2011) mint:MINT-8085412|pubmed:21251912|doi:10.1016/j.febslet.2011.01.024|mint:d-10-02213 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8566572|mint:MINT-8085512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-8085520(identity) ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1|mint:MINT-8085514(identity) - - - comment:homomint|comment:mint|figure legend:f3a f3b taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/01/12 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606 intact-crc:5CE7442996B1C12D|rigid:oOGdNlz2EefzBsPotuf+/EAcmjs false binding-associated region:326-430(MINT-8085521) glutathione s tranferase tag:?-?(MINT-8085515)|binding-associated region:509-630(MINT-8085517) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)