#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P43136 uniprotkb:O35626 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4319978|imex:IM-16862-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:16E513ECB0073510|rigid:g7r6Af6CF7cW2JgUYerLHGZWrWM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P27790 uniprotkb:O35626 intact:EBI-4325251|uniprotkb:Q7TSG8|ensembl:ENSMUSP00000086938 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:cenpb_mouse(display_long)|uniprotkb:Cenpb(gene name)|psi-mi:Cenpb(display_short)|uniprotkb:Cenp-b(gene name synonym)|uniprotkb:Centromere protein B(gene name synonym) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325272|imex:IM-16862-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031708.2|ensembl:ENSMUSG00000068267(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0016604"(nuclear body)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015115(Centromere protein B dimerisation)|interpro:IPR033062|interpro:IPR034882|ensembl:ENSMUST00000089510(transcript) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:ko0V+0Awb9m2NP/vTc6m2L/HRGY10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:BBB37E84B2655BB1|rigid:ZJOQT5VzaE0RTeu2A/wk04nfrPM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35626 uniprotkb:P62874 intact:EBI-4319979|ensembl:ENSMUSP00000051959 intact:EBI-357152|ensembl:ENSMUSP00000030940|ensembl:ENSMUSP00000101241|ensembl:ENSMUSP00000130123|ensembl:ENSMUSP00000135091|uniprotkb:P04901|uniprotkb:P04697 psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:gbb1_mouse(display_long)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325276|imex:IM-16862-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) ensembl:ENSMUSG00000029064(gene)|ensembl:ENSMUST00000030940(transcript)|ensembl:ENSMUST00000105616(transcript)|ensembl:ENSMUST00000165335(transcript)|ensembl:ENSMUST00000176637(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007603"(phototransduction, visible light)|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-8964616|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62874|rcsb pdb:6K41|rcsb pdb:6K42|rcsb pdb:6RMV|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-2485179|reactome:R-MMU-381676|reactome:R-MMU-381753|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|refseq:NP_001153488.1|refseq:NP_001153489.1|refseq:NP_032168.1|refseq:XP_017175466.1 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10090 intact-crc:C8AA487D006A5EEB|rigid:tf3L5M8f2+WR+K30upI2h1BgYfk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35626 uniprotkb:Q9JJ00 intact:EBI-4319979|ensembl:ENSMUSP00000051959 intact:EBI-4325280|uniprotkb:O54730|uniprotkb:O54731|uniprotkb:Q9D1F8|ensembl:ENSMUSP00000091318|ensembl:ENSMUSP00000139479 psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:pls1_mouse(display_long)|uniprotkb:Plscr1(gene name)|psi-mi:Plscr1(display_short)|uniprotkb:Tra1b(gene name synonym)|uniprotkb:Tras1(gene name synonym)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Transplantability-associated protein 1(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325299|imex:IM-16862-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) refseq:NP_035766.2|refseq:XP_006511115.1|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUSG00000032369(gene)|ensembl:ENSMUST00000093801(transcript)|ensembl:ENSMUST00000186364(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|go:"GO:0051607"(defense response to virus) - - - figure legend:Fig. 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 rogid:Ftjwb/9IHEpxXXqDnvxciGDXwPA10090 intact-crc:7557DB04FBFEB415|rigid:dgsTg2F667Bp+Hn0QtMeBTNPk9w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62420 uniprotkb:O35626 intact:EBI-77971|ensembl:ENSMUSP00000030212|uniprotkb:Q3UTL7|uniprotkb:Q3UY49|uniprotkb:Q8BXS6|uniprotkb:Q8VBV1 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:sh3g2_mouse(display_long)|uniprotkb:Sh3gl2(gene name)|psi-mi:Sh3gl2(display_short)|uniprotkb:Sh3d2a(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:Een1(gene name synonym)|uniprotkb:SH3p4(gene name synonym) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325302|imex:IM-16862-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035824|interpro:IPR036028|mint:Q62420|rcsb pdb:1ZWW|reactome:R-MMU-177504|reactome:R-MMU-182971|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0008022"(protein C-terminus binding)|ensembl:ENSMUSG00000028488(gene)|ensembl:ENSMUST00000030212(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|refseq:NP_062408.2|dip:DIP-30992N refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:hAkiLVjGXejkjd5pRcuq9wVXrfk10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:F32E6E800A238472|rigid:YhHj+veeZxLfKa289NUjHiUivcI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35626 uniprotkb:Q920B9 intact:EBI-4319979|ensembl:ENSMUSP00000051959 intact:EBI-2549823|uniprotkb:Q3TZ48|uniprotkb:Q3UFH0|uniprotkb:Q921H4 psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:sp16h_mouse(display_long)|uniprotkb:Supt16h(gene name)|psi-mi:Supt16h(display_short)|uniprotkb:Fact140(gene name synonym)|uniprotkb:Factp140(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:Supt16(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325306|imex:IM-16862-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|interpro:IPR029148|reactome:R-MMU-6804756|reactome:R-MMU-75955|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|refseq:NP_291096.2|dip:DIP-55972N|mint:Q920B9 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 rogid:qcl0ckY0w3tIem/ezLyPtHVUnZA10090 intact-crc:CCD3F9EAA1B8F8C1|rigid:JbQfBbkBu+iHqXTVNOeBe82sz1s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35626 uniprotkb:Q8CG79 intact:EBI-4319979|ensembl:ENSMUSP00000051959 intact:EBI-645416|uniprotkb:Q3UYM7|uniprotkb:Q8K2L5 psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:aspp2_mouse(display_long)|uniprotkb:Tumor suppressor p53-binding protein 2(gene name synonym)|uniprotkb:Tp53bp2(gene name)|psi-mi:Tp53bp2(display_short)|uniprotkb:Aspp2(gene name synonym)|uniprotkb:Trp53bp2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325310|imex:IM-16862-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) refseq:NP_775554.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001452(Src homology-3)|interpro:IPR029071|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR036028|interpro:IPR036770|reactome:R-MMU-6804759 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 rogid:Ygl3S/FVLP/3gD2F0o5t016B2Bk10090 intact-crc:B0E63FB3C13549A1|rigid:Ni2XXR6VhePH7bH/zJbpd0q9E7g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P68510 uniprotkb:O35626 intact:EBI-444641|uniprotkb:P11576|uniprotkb:P70198|uniprotkb:Q3TGZ9|ensembl:ENSMUSP00000019109 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:1433f_mouse(display_long)|uniprotkb:Ywhah(gene name)|psi-mi:Ywhah(display_short) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4325314|imex:IM-16862-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035868.1|ensembl:ENSMUSG00000018965(gene)|ensembl:ENSMUST00000019109(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P68510|rcsb pdb:5YQG|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035 refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/08/02 2014/10/16 rogid:Ew2uUYIXrZ8nnP52xMnGB6KOCqc10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:DD15CE58BE7C0F82|rigid:gp8khKhf1bI7rLlScb38lc3v0ws false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43136 uniprotkb:O35626 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320301|imex:IM-16862-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Figure 1C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/08/02 2014/10/16 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:63150CFE3EC63A60|rigid:g7r6Af6CF7cW2JgUYerLHGZWrWM false glutathione s tranferase tag:?-? his tag:?-?|ha tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9Y272 uniprotkb:P10588 intact:EBI-740818|uniprotkb:B4DFF4|ensembl:ENSP00000225688|uniprotkb:Q9NYB4|uniprotkb:B2R709 intact:EBI-2681496|uniprotkb:Q6P586|uniprotkb:B2RC68|uniprotkb:Q9BUE8|uniprotkb:Q5XGA0|ensembl:ENSP00000291442 psi-mi:rasd1_human(display_long)|uniprotkb:Activator of G-protein signaling 1(gene name synonym)|uniprotkb:RASD1(gene name)|psi-mi:RASD1(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:DEXRAS1(gene name synonym) psi-mi:nr2f6_human(display_long)|uniprotkb:EAR2(gene name synonym)|uniprotkb:ERBAL2(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym)|uniprotkb:NR2F6(gene name)|psi-mi:NR2F6(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320347|imex:IM-16862-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186918.1|refseq:NP_057168.1|ensembl:ENSG00000108551(gene)|ensembl:ENST00000225688(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0005634"(nucleus) refseq:NP_005225.2|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-HSA-383280|ensembl:ENST00000291442(transcript)|ensembl:ENSG00000160113(gene) - - - figure legend:Figure 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/08/02 2014/10/16 rogid:89DnCUqLmPDbyBRpKAWdKksaYgY9606 rogid:x2mPGv2avd+xfMIe8n47xUjGgS89606 intact-crc:FEE845135254980F|rigid:qGHywkeGaj66chpwEJAAFTM0jIc false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P43136 uniprotkb:O35626 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320360|imex:IM-16862-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Figure 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2011/08/02 2014/10/16 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:0FCC97FD0D985FEC|rigid:g7r6Af6CF7cW2JgUYerLHGZWrWM false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P43136 uniprotkb:O35626 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 intact:EBI-4319979|ensembl:ENSMUSP00000051959 psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:"MI:0096"(pull down) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4320469|imex:IM-16862-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - - figure legend:Figure 1B and 4B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/08/02 2014/10/16 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 intact-crc:66D1F772382CA888|rigid:g7r6Af6CF7cW2JgUYerLHGZWrWM false necessary binding region:194-390|glutathione s tranferase tag:?-? his tag:?-?|ha tag:?-?|mutation decreasing interaction:34-34|mutation decreasing interaction:81-81 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O35626 uniprotkb:P43136 intact:EBI-4319979|ensembl:ENSMUSP00000051959 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 psi-mi:rasd1_mouse(display_long)|uniprotkb:Rasd1(gene name)|psi-mi:Rasd1(display_short)|uniprotkb:Dexras1(gene name synonym) psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Tan et al. (2011) pubmed:21247419|imex:IM-16862 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-4320486|imex:IM-16862-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033052.1|ensembl:ENSMUSG00000049892(gene)|ensembl:ENSMUST00000062405(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0045892"(negative regulation of transcription, DNA-templated) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - - figure legend:Figure 5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/08/02 2014/10/16 rogid:DF/5YVj95Ls7bDI2YOzToj0TF8U10090 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 intact-crc:A536BC2409376853|rigid:g7r6Af6CF7cW2JgUYerLHGZWrWM false his tag:?-?|ha tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)