#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32248	uniprotkb:O00585	intact:EBI-3401578|ensembl:ENSP00000246657	intact:EBI-953695|ensembl:ENSP00000259607|uniprotkb:Q6ICR7	psi-mi:ccr7_human(display_long)|uniprotkb:CCR7(gene name)|psi-mi:CCR7(display_short)|uniprotkb:CMKBR7(gene name synonym)|uniprotkb:EBI1(gene name synonym)|uniprotkb:EVI1(gene name synonym)|uniprotkb:BLR2(gene name synonym)|uniprotkb:CDw197(gene name synonym)|uniprotkb:Epstein-Barr virus-induced G-protein coupled receptor 1(gene name synonym)|uniprotkb:MIP-3 beta receptor(gene name synonym)	psi-mi:ccl21_human(display_long)|uniprotkb:Small-inducible cytokine A21(gene name synonym)|uniprotkb:Beta-chemokine exodus-2(gene name synonym)|uniprotkb:6Ckine(gene name synonym)|uniprotkb:Secondary lymphoid-tissue chemokine(gene name synonym)|uniprotkb:CCL21(gene name)|psi-mi:CCL21(display_short)|uniprotkb:SCYA21(gene name synonym)|uniprotkb:UNQ784/PRO1600(orf name)	psi-mi:"MI:0813"(proximity ligation assay)	Yin et al. (2010)	pubmed:21172016|imex:IM-15304	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:1263"(Molecular Connections)	intact:EBI-3401601|imex:IM-15304-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|ensembl:ENSG00000126353(gene)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|ensembl:ENST00000246657(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0002408"(myeloid dendritic cell chemotaxis)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031529"(ruffle organization)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002885"(positive regulation of hypersensitivity)|go:"GO:0002922"(positive regulation of humoral immune response)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0005739"(mitochondrion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005886"(plasma membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035757"("chemokine (C-C motif) ligand 19 binding")|go:"GO:0038117"(C-C motif chemokine 19 receptor activity)|go:"GO:0038121"(C-C motif chemokine 21 receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000522"(positive regulation of immunological synapse formation)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000526"(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation)|go:"GO:2000547"(regulation of dendritic cell dendrite assembly)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|go:"GO:0035758"("chemokine (C-C motif) ligand 21 binding")|interpro:IPR001718(C-C chemokine receptor, type 7)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6QZH|reactome:R-HSA-380108|reactome:R-HSA-418594|refseq:NP_001829.1|refseq:NP_001288643.1|refseq:NP_001288645.1|refseq:NP_001288646.1|refseq:NP_001288647.1|dip:DIP-5855N	ensembl:ENSG00000137077(gene)|ensembl:ENST00000259607(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031529"(ruffle organization)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031732"(CCR7 chemokine receptor binding)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035759"(mesangial cell-matrix adhesion)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048020"(CCR chemokine receptor binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048469"(cell maturation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097026"(dendritic cell dendrite assembly)|go:"GO:1903237"(negative regulation of leukocyte tethering or rolling)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000529"(positive regulation of myeloid dendritic cell chemotaxis)|go:"GO:2000548"(negative regulation of dendritic cell dendrite assembly)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|interpro:IPR030593|interpro:IPR034133|interpro:IPR036048|interpro:IPR039809|mint:O00585|rcsb pdb:2L4N|rcsb pdb:5EKI|reactome:R-HSA-380108|reactome:R-HSA-418594|interpro:IPR001811(Small chemokine, interleukin-8-like)|refseq:NP_002980.1|dip:DIP-5854N	psi-mi:"MI:0469"(intact)	-	-	figure legend:fig. 6c|agonist:heparan sulfate|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2011/01/07	2014/10/16	rogid:dfneBfr/6GxvjUI8dc9dUsqQWp09606	rogid:kCftuxbCJ6ojbhtg8Tloh6nUv5Q9606	intact-crc:C3FD6AAB306C40D7|rigid:PendPNJyUCm0N/6Od04xcsf0Fmc	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)