#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9CW03 uniprotkb:Q9CU62 intact:EBI-2550068|ensembl:ENSMUSP00000025930|uniprotkb:O35667|uniprotkb:Q9QUS3 intact:EBI-2550016|uniprotkb:A2AFQ5|ensembl:ENSMUSP00000044645|uniprotkb:Q3V480|uniprotkb:Q9CUX9|uniprotkb:Q9D959|uniprotkb:Q9WTU1 psi-mi:smc3_mouse(display_long)|uniprotkb:Smc3(gene name)|psi-mi:Smc3(display_short)|uniprotkb:Bam(gene name synonym)|uniprotkb:Bmh(gene name synonym)|uniprotkb:Cspg6(gene name synonym)|uniprotkb:Mmip1(gene name synonym)|uniprotkb:Smc3l1(gene name synonym)|uniprotkb:Smcd(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome segregation protein SmcD(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:Mad member-interacting protein 1(gene name synonym) psi-mi:smc1a_mouse(display_long)|uniprotkb:Smc1a(gene name)|psi-mi:Smc1a(display_short)|uniprotkb:Smc1(gene name synonym)|uniprotkb:Smc1l1(gene name synonym)|uniprotkb:Smcb(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)|uniprotkb:Chromosome segregation protein SmcB(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8536291|mint:MINT-8098309|imex:IM-15442-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024974(gene)|ensembl:ENSMUST00000025930(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9CW03|rcsb pdb:2WD5|reactome:R-MMU-2467813|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_031816.2|dip:DIP-57028N|mint:MINT-8098312(identity) ensembl:ENSMUSG00000041133(gene)|ensembl:ENSMUST00000045312(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|go:"GO:0008278"(cohesin complex)|interpro:IPR036277|mint:Q9CU62|rcsb pdb:2WD5|reactome:R-MMU-2467813|interpro:IPR029683|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_062684.2|dip:DIP-57021N|mint:MINT-8098311(identity) - - - comment:homomint|comment:mint|figure legend:st1 st2 f1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/17 2014/10/16 rogid:9tJqVTJ2k3viYrJVtDfH2TekFIg10090 rogid:3TtjC4Y8krgvnUafgy2DG2XTnH810090 intact-crc:C079D98524614C2F|rigid:LeZBM292C5jLEERTl3zw6TW1Gss false binding-associated region:484-696(MINT-8098448) binding-associated region:?-?(MINT-8098442) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32908 uniprotkb:P47037 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8536322|mint:MINT-8098533|imex:IM-15442-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N|mint:MINT-8098535(identity) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8098536(identity) - crc64:B504017AA0ECCA8C crc64:B152D88F7780341F figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.2x10^-8(molar) 2011/02/17 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:23F36A97A193E2AE|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8536335|mint:MINT-8099488|imex:IM-15442-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099493(identity) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N|mint:MINT-8099491(identity) - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.9x10^-8(molar) 2011/02/17 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:712B5D745DF9797D|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false mutation decreasing interaction:665-665(MINT-8099498)|mutation decreasing interaction:669-669(MINT-8099504)|mutation decreasing interaction:668-668(MINT-8099501) mutation decreasing interaction:661-661(MINT-8099511)|mutation decreasing interaction:554-554(MINT-8099508) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47037 uniprotkb:Q12158 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8536377|mint:MINT-8099557|imex:IM-15442-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099563(identity) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158|mint:MINT-8099570(identity) - crc64:B152D88F7780341F crc64:EB6C7CA33BAC208F comment:homomint|comment:mint|figure legend:sf5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/02/17 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:E832F8B05F8C00F2|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-?(MINT-8099564) tag:?-?(MINT-8099575) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8536377|mint:MINT-8099557|imex:IM-15442-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099563(identity) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N|mint:MINT-8099559(identity) - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C comment:homomint|comment:mint|figure legend:sf5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/02/17 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:E832F8B05F8C00F2|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-?(MINT-8099564) myc tag:?-?(MINT-8099571) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q04264 uniprotkb:P47037 intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8536401|mint:MINT-8099579|imex:IM-15442-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257|mint:MINT-8099589(identity) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099585(identity) - - crc64:B152D88F7780341F comment:homomint|comment:mint|figure legend:sf5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2011/02/17 2014/10/16 rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:2A0ED22256A17AB4|rigid:l1nT3acUOPu/LyXDMN037F7FzjY false tag:?-?(MINT-8099590) ha tag:?-?(MINT-8099586) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32908 uniprotkb:P47037 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8536428|mint:MINT-8099528|imex:IM-15442-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N|mint:MINT-8099530(identity) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099532(identity) - crc64:B504017AA0ECCA8C crc64:B152D88F7780341F comment:homomint|comment:mint|figure legend:f4b f4c f4d f4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/17 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:A3696446BF1877AA|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false - flag tag:?-?(MINT-8099537) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8536443|mint:MINT-8099543|imex:IM-15442-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099547(identity) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N|mint:MINT-8099545(identity) - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:f4f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/17 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:288E48B03693927D|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false flag tag:?-?(MINT-8099548) mutation disrupting interaction:665-665(MINT-8099553) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kurze et al. (2011) mint:MINT-8098172|pubmed:21139566|imex:IM-15442|doi:10.1038/emboj.2010.315 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8536471|mint:MINT-8099515|imex:IM-15442-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037|mint:MINT-8099520(identity) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N|mint:MINT-8099518(identity) - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/17 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:C961CFE2EA5896F6|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)