#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54823	uniprotkb:Q4VGL6	intact:EBI-3647041|ensembl:ENSMUSP00000128421|ensembl:ENSMUSP00000149620|uniprotkb:O54979|uniprotkb:Q3UFI3|uniprotkb:Q8BW68	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:ddx6_mouse(display_long)|uniprotkb:Ddx6(gene name)|psi-mi:Ddx6(display_short)|uniprotkb:Hlr2(gene name synonym)|uniprotkb:Rck(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:Oncogene RCK homolog(gene name synonym)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647036|imex:IM-17247-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|mint:P54823|reactome:R-MMU-430039|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|ensembl:ENSMUSG00000032097(gene)|ensembl:ENSMUST00000170489(transcript)|ensembl:ENSMUST00000217034(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_001104296.1|refseq:NP_031867.1|refseq:NP_851841.2|refseq:XP_011240693.1|refseq:XP_011240694.1|refseq:XP_017168613.1	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0010494"(cytoplasmic stress granule)	-	-	figure legend:Fig. 2D|comment:primary CD4+ T cells were stimulated with anti-CD3 and anti-CD28 for 48hrs, many of the rc3h1-enriched foci in CD4+ T cells showed full colocalization with Rck and Fmrp in 62% of the cells|stimulant:arsenite treatment induced cytoplasmic foci formation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2011/02/28	2014/10/16	rogid:Q80hxmsbz9kQgOP9Gflto87Sp/M10090	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	intact-crc:B582B05214D171C6|rigid:fWuPK+753ChNqHGOOJRM3r524d8	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P26196	uniprotkb:Q13283	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647085|imex:IM-17247-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1	go:"GO:0005737"(cytoplasm)	-	-	figure legend:Fig. 3A, S1B|comment:"rc3h1(1-749) mutant showed impaired foci formation in absence of arsenite, but were still able to translocate into stress granules"|stimulant:arsenite|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/28	2014/10/16	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606	intact-crc:BDA819F53F024207|rigid:BmLXn9lLUAM3HpPAHmd+rtnztmc	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P26196	uniprotkb:Q4VGL6	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647085|imex:IM-17247-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0005737"(cytoplasm)	-	-	figure legend:Fig. 3A, S1B|comment:"rc3h1(1-749) mutant showed impaired foci formation in absence of arsenite, but were still able to translocate into stress granules"|stimulant:arsenite|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/28	2014/10/16	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	intact-crc:BDA819F53F024207|rigid:BmLXn9lLUAM3HpPAHmd+rtnztmc	false	-	green fluorescent protein tag:?-?|sufficient binding region:1-749	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P26196	uniprotkb:Q6P2E9	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647072|imex:IM-17247-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N	go:"GO:0010494"(cytoplasmic stress granule)	-	-	figure legend:Fig. S2D|stimulant:arsenite|caution:edc4 was detected using an antibody against the nuclear p70 s6 kinase a that is known to crossreact with the cytoplasmic edc4 protein|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/28	2014/10/16	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606	intact-crc:68AEE7146026CC93|rigid:wT7fDHELS5AjIipbYhk+NW2k+ZQ	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P26196	uniprotkb:Q4VGL6	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647072|imex:IM-17247-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0010494"(cytoplasmic stress granule)	-	-	figure legend:Fig. S2D|stimulant:arsenite|caution:edc4 was detected using an antibody against the nuclear p70 s6 kinase a that is known to crossreact with the cytoplasmic edc4 protein|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/28	2014/10/16	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	intact-crc:68AEE7146026CC93|rigid:wT7fDHELS5AjIipbYhk+NW2k+ZQ	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P26196	uniprotkb:Q4VGL6	intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym)	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647058|imex:IM-17247-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0010494"(cytoplasmic stress granule)	-	-	figure legend:Fig. 3A, S1B|comment:"rc3h1(1-749) mutant showed impaired foci formation in absence of arsenite, but were still able to translocate into stress granules"|stimulant:arsenite|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/02/28	2014/10/16	rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	intact-crc:F591FDF4EE8D49A4|rigid:YMTdJgnieOpeRhGaAhhV6WgnSzA	false	-	green fluorescent protein tag:?-?|sufficient binding region:1-749	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q4VGL6	uniprotkb:P54823	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	intact:EBI-3647041|ensembl:ENSMUSP00000128421|ensembl:ENSMUSP00000149620|uniprotkb:O54979|uniprotkb:Q3UFI3|uniprotkb:Q8BW68	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:ddx6_mouse(display_long)|uniprotkb:Ddx6(gene name)|psi-mi:Ddx6(display_short)|uniprotkb:Hlr2(gene name synonym)|uniprotkb:Rck(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:Oncogene RCK homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647113|imex:IM-17247-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|mint:P54823|reactome:R-MMU-430039|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|ensembl:ENSMUSG00000032097(gene)|ensembl:ENSMUST00000170489(transcript)|ensembl:ENSMUST00000217034(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_001104296.1|refseq:NP_031867.1|refseq:NP_851841.2|refseq:XP_011240693.1|refseq:XP_011240694.1|refseq:XP_017168613.1	-	-	-	figure legend:Fig. 4A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2011/02/28	2014/10/16	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rogid:Q80hxmsbz9kQgOP9Gflto87Sp/M10090	intact-crc:1CEF612FAD51A700|rigid:mV2oThfRf8tcHpwXdheCTAu4NBI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4VGL6	uniprotkb:Q3UJB9	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	intact:EBI-2553526|uniprotkb:Q3U6U8|uniprotkb:Q8R223|uniprotkb:Q7TS78	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:edc4_mouse(display_long)|uniprotkb:Edc4(gene name)|psi-mi:Edc4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647113|imex:IM-17247-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|reactome:R-MMU-430039|refseq:NP_001288029.1|interpro:IPR032401|refseq:NP_853625.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|mint:Q3UJB9	-	-	-	figure legend:Fig. 4A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2011/02/28	2014/10/16	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rogid:FVX5K/2axUrzI66j1QPmJsqpxec10090	intact-crc:1CEF612FAD51A700|rigid:mV2oThfRf8tcHpwXdheCTAu4NBI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4VGL6	uniprotkb:Q3UJB9	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	intact:EBI-2553526|uniprotkb:Q3U6U8|uniprotkb:Q8R223|uniprotkb:Q7TS78	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:edc4_mouse(display_long)|uniprotkb:Edc4(gene name)|psi-mi:Edc4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647146|imex:IM-17247-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|reactome:R-MMU-430039|refseq:NP_001288029.1|interpro:IPR032401|refseq:NP_853625.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|mint:Q3UJB9	-	-	-	figure legend:Fig. 4C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2011/02/28	2014/10/16	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rogid:FVX5K/2axUrzI66j1QPmJsqpxec10090	intact-crc:32FF20A6C93B95C9|rigid:J1HGtj3YtprRytgewmntOKp+cvw	false	sufficient binding region:1-509|green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4VGL6	uniprotkb:P54823	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	intact:EBI-3647041|ensembl:ENSMUSP00000128421|ensembl:ENSMUSP00000149620|uniprotkb:O54979|uniprotkb:Q3UFI3|uniprotkb:Q8BW68	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:ddx6_mouse(display_long)|uniprotkb:Ddx6(gene name)|psi-mi:Ddx6(display_short)|uniprotkb:Hlr2(gene name synonym)|uniprotkb:Rck(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:Oncogene RCK homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647129|imex:IM-17247-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|mint:P54823|reactome:R-MMU-430039|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|ensembl:ENSMUSG00000032097(gene)|ensembl:ENSMUST00000170489(transcript)|ensembl:ENSMUST00000217034(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_001104296.1|refseq:NP_031867.1|refseq:NP_851841.2|refseq:XP_011240693.1|refseq:XP_011240694.1|refseq:XP_017168613.1	-	-	-	figure legend:Fig. 4B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2011/02/28	2014/10/16	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rogid:Q80hxmsbz9kQgOP9Gflto87Sp/M10090	intact-crc:3AAA40020F8D52BD|rigid:mV2oThfRf8tcHpwXdheCTAu4NBI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4VGL6	uniprotkb:Q3UJB9	intact:EBI-2366263|uniprotkb:Q69Z31|uniprotkb:B2RS13|ensembl:ENSMUSP00000124871	intact:EBI-2553526|uniprotkb:Q3U6U8|uniprotkb:Q8R223|uniprotkb:Q7TS78	psi-mi:rc3h1_mouse(display_long)|uniprotkb:Rc3h1(gene name)|psi-mi:Rc3h1(display_short)|uniprotkb:Gm551(gene name synonym)|uniprotkb:Kiaa2025(gene name synonym)|uniprotkb:RING finger and C3H zinc finger protein 1(gene name synonym)|uniprotkb:Protein Sanroque(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 1(gene name synonym)	psi-mi:edc4_mouse(display_long)|uniprotkb:Edc4(gene name)|psi-mi:Edc4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Glasmacher et al. (2010)	pubmed:20639877|imex:IM-17247	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-3647129|imex:IM-17247-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020123.1|ensembl:ENSMUSG00000040423(gene)|ensembl:ENSMUST00000161609(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0033962"(P-body assembly)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045623"(negative regulation of T-helper cell differentiation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1900151"(regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032671|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4QI0|rcsb pdb:4QI2|rcsb pdb:4TXA|rcsb pdb:5F5F|rcsb pdb:5F5H|rcsb pdb:6TQA|rcsb pdb:6TQB	go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|reactome:R-MMU-430039|refseq:NP_001288029.1|interpro:IPR032401|refseq:NP_853625.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|mint:Q3UJB9	-	-	-	figure legend:Fig. 4B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2011/02/28	2014/10/16	rogid:MRRQ1OTzvG6aSUot+T7O69K1jxo10090	rogid:FVX5K/2axUrzI66j1QPmJsqpxec10090	intact-crc:3AAA40020F8D52BD|rigid:mV2oThfRf8tcHpwXdheCTAu4NBI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)