#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9WU22	uniprotkb:P24161	intact:EBI-7249866|intact:MINT-126937|uniprotkb:G5E8E7|ensembl:ENSMUSP00000067614	intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3	psi-mi:ptn4_mouse(display_long)|uniprotkb:Ptpn4(gene name)|psi-mi:Ptpn4(display_short)|uniprotkb:Testis-enriched protein tyrosine phosphatase(gene name synonym)	psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Young et al. (2008)	doi:10.1016/j.molimm.2008.05.023|pubmed:18614237|mint:MINT-8296413	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8011255|mint:MINT-8296818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064317.2|ensembl:ENSMUSG00000026384(gene)|ensembl:ENSMUST00000064091(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012151(Protein-tyrosine phosphatase, non-receptor type-3, -4)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR041783|mint:MINT-8296820(identity)	refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1|mint:MINT-8296821(identity)	-	comment:mint|function:May act at junctions between the membrane and the cytoskeleton	comment:mint	figure legend:F1A|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:f0q7V4YMwX+v4tFgx3DePzQc3X010090	rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090	intact-crc:D5A4546340F01159|rigid:nbuYl8QtS2dWo8/D3DUpq2QZuRQ	false	trapping mutant:?-?(MINT-8296825)|trapping mutant:842-842(MINT-8296826)	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:A2ALK8	uniprotkb:P24161	intact:EBI-8011291|intact:MINT-8296855|ensembl:ENSMUSP00000075063	intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3	psi-mi:ptn3_mouse(display_long)|uniprotkb:Ptpn3(gene name)|psi-mi:Ptpn3(display_short)	psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Young et al. (2008)	doi:10.1016/j.molimm.2008.05.023|pubmed:18614237|mint:MINT-8296413	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8011287|mint:MINT-8297847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035337.2|refseq:XP_006538161.1|refseq:XP_006538162.1|refseq:XP_006538163.1|ensembl:ENSMUSG00000038764(gene)|ensembl:ENSMUST00000075637(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0051117"(ATPase binding)|go:"GO:0097421"(liver regeneration)|go:"GO:0098902"(regulation of membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012151(Protein-tyrosine phosphatase, non-receptor type-3, -4)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR041783|reactome:R-MMU-182971|reactome:R-MMU-5675221|mint:MINT-8297849(identity)	refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1|mint:MINT-8297853(identity)	-	comment:mint	comment:mint	figure legend:F1A|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:f3JSk5YCTctQ7fLgqonaA316V7E10090	rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090	intact-crc:33C932E09C34C840|rigid:K4Ty4uIu3lX4R0XnDcCazzQo8cM	false	trapping mutant:?-?(MINT-8297852)|trapping mutant:842-842(MINT-8297850)	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P24161	uniprotkb:Q9WU22	intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3	intact:EBI-7249866|intact:MINT-126937|uniprotkb:G5E8E7|ensembl:ENSMUSP00000067614	psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)	psi-mi:ptn4_mouse(display_long)|uniprotkb:Ptpn4(gene name)|psi-mi:Ptpn4(display_short)|uniprotkb:Testis-enriched protein tyrosine phosphatase(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Young et al. (2008)	doi:10.1016/j.molimm.2008.05.023|pubmed:18614237|mint:MINT-8296413	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8011342|mint:MINT-8296834	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1|mint:MINT-8296837(identity)	refseq:NP_064317.2|ensembl:ENSMUSG00000026384(gene)|ensembl:ENSMUST00000064091(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012151(Protein-tyrosine phosphatase, non-receptor type-3, -4)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR041783|mint:MINT-8296836(identity)	-	comment:mint	comment:mint|function:May act at junctions between the membrane and the cytoskeleton	figure legend:F1B|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/11/29	2014/10/16	rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090	rogid:f0q7V4YMwX+v4tFgx3DePzQc3X010090	intact-crc:04BF0D8D3B1FABBB|rigid:nbuYl8QtS2dWo8/D3DUpq2QZuRQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WU22	uniprotkb:P24161	intact:EBI-7249866|intact:MINT-126937|uniprotkb:G5E8E7|ensembl:ENSMUSP00000067614	intact:EBI-7803400|uniprotkb:P29020|ensembl:ENSMUSP00000005907|intact:MINT-7895650|uniprotkb:Q9D3G3	psi-mi:ptn4_mouse(display_long)|uniprotkb:Ptpn4(gene name)|psi-mi:Ptpn4(display_short)|uniprotkb:Testis-enriched protein tyrosine phosphatase(gene name synonym)	psi-mi:cd3z_mouse(display_long)|uniprotkb:Cd247(gene name)|psi-mi:Cd247(display_short)|uniprotkb:Cd3z(gene name synonym)|uniprotkb:Tcrz(gene name synonym)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Young et al. (2008)	doi:10.1016/j.molimm.2008.05.023|pubmed:18614237|mint:MINT-8296413	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8011450|mint:MINT-8296845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064317.2|ensembl:ENSMUSG00000026384(gene)|ensembl:ENSMUST00000064091(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012151(Protein-tyrosine phosphatase, non-receptor type-3, -4)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR041783|mint:MINT-8296847(identity)	refseq:XP_011237047.1|refseq:NP_112439.1|refseq:XP_017168774.1|ensembl:ENSMUSG00000005763(gene)|ensembl:ENSMUST00000005907(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR024128|reactome:R-MMU-198933|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-2029481|reactome:R-MMU-2029482|reactome:R-MMU-2029485|reactome:R-MMU-389948|mint:P24161|refseq:NP_001106862.1|mint:MINT-8296848(identity)	-	comment:mint|function:May act at junctions between the membrane and the cytoskeleton	comment:mint	figure legend:F1C|comment:mint|partial coverage:partial coverage	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/11/29	2014/10/16	rogid:f0q7V4YMwX+v4tFgx3DePzQc3X010090	rogid:Ac52AvET/m0LboX+dKOOhfmE4B010090	intact-crc:D2F6620882CF7750|rigid:nbuYl8QtS2dWo8/D3DUpq2QZuRQ	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)