#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8IZJ1	uniprotkb:Q8CGU4	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409135|imex:IM-16880-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:1a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/09/22	2014/10/16	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:2D192C687C192FFC|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	sufficient binding region:568-945	sufficient binding region:403..403-685..685	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZJ1	uniprotkb:Q8CGU4	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409339|imex:IM-16880-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:2b, 3a|agonist:The presence of purified netrin-1 is required for the interaction to happen.|inhibition:"The interaction is inhibited by PP2 (selective inhibitor of Fyn, a tyrosine kinase that phosphorylates unc5b), genistein and compund 5 (both tyrosine kinase inhibitors)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:8A98DEE0089D6692|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	ha tag:?-?	mutation disrupting interaction:1124-1124,1032-1032|mutation disrupting interaction:1124-1124|myc tag:?-?|mutation disrupting interaction:1032-1032	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CGU4	uniprotkb:Q8IZJ1	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409317|imex:IM-16880-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	-	-	-	figure legend:2a|agonist:The presence of purified netrin-1 is required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	intact-crc:2609D74E619AF4AE|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	mutation disrupting interaction:413-413,414-414|green fluorescent protein tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CGU4	uniprotkb:Q8IZJ1	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409385|imex:IM-16880-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	-	-	-	figure legend:2b, S6, 3a, S1c|agonist:"The presence of purified netrin-1 is required for the interaction to happen (figs. 2b, S6 and 3a). In the absence of netrin-1, the presence of FynA is required (fig. S1c)."|inhibition:"The interaction is inhibited by PP2 (selective inhibitor of Fyn, a tyrosine kinase that phosphorylates unc5b), genistein and compund 5 (both tyrosine kinase inhibitors)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	intact-crc:71EC242550E45185|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	mutation disrupting interaction:1124-1124|myc tag:?-?|mutation disrupting interaction:1032-1032|mutation disrupting interaction:1124-1124,1032-1032	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IZJ1	uniprotkb:Q8CGU4	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409164|imex:IM-16880-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:6A01C0798A2A6F52|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	ha tag:?-?|sufficient binding region:568-945|necessary binding region:568-853	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CGU4	uniprotkb:Q8IZJ1	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409210|imex:IM-16880-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	-	-	-	figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	intact-crc:0906C3D810FC85D2|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	myc tag:?-?|necessary binding region:403..403-685..685	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CGU4	uniprotkb:Q8IZJ1	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409187|imex:IM-16880-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	-	-	-	figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	intact-crc:A0ABEC906972BC9F|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	green fluorescent protein tag:?-?	sufficient binding region:568-945|ha tag:?-?|necessary binding region:568-853	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8CGU4	uniprotkb:Q63155	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-1798965	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409636|imex:IM-16880-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3	-	-	-	figure legend:S2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116	intact-crc:0267A7854B4617BD|rigid:Xcuxg1Fwk66ZZGV+7IrIZIFZuO4	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IZJ1	uniprotkb:Q8CGU4	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409232|imex:IM-16880-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:72453B8AA75C2EC1|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	ha tag:?-?	necessary binding region:403..403-685..685|myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IZJ1	uniprotkb:Q8CGU4	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409545|imex:IM-16880-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:S1c|agonist:The presence of FynA is required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/09/22	2014/10/16	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:C3F64D23655B978D|rigid:ZOr0Kk+pz150I+vumHCmTlDohUk	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O08722	uniprotkb:Q8CGU4	intact:EBI-4404185	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409313|imex:IM-16880-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	go:"GO:0044297"(cell body)|go:"GO:0043005"(neuron projection)	-	-	figure legend:1d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain)	-	2011/09/22	2014/10/16	rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:F3988AFCC884BD55|rigid:RvJ7lBTIh7Tj/GCta+Ug3H8bJto	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8CGU4	uniprotkb:O08722	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-4404185	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409249|imex:IM-16880-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft)	-	-	-	figure legend:1c, S6, 2c|inhibition:"This interaction is disrupted by tyrosine-kinase inhibitors genistein adn PP2 (fig. 2c)."|agonist:"The presence of netrin-1 increases the interaction (fig. 2c)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116	intact-crc:277E60FFD7AC4EBF|rigid:RvJ7lBTIh7Tj/GCta+Ug3H8bJto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08722	uniprotkb:Q8CGU4	intact:EBI-4404185	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409405|imex:IM-16880-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:1c, S6, 2c|inhibition:"This interaction is disrupted by tyrosine-kinase inhibitors genistein adn PP2 (fig. 2c)."|agonist:"The presence of netrin-1 increases the interaction (fig. 2c)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2011/09/22	2014/10/16	rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:48F2D5EDE682E736|rigid:RvJ7lBTIh7Tj/GCta+Ug3H8bJto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08722	uniprotkb:Q8CGU4	intact:EBI-4404185	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409281|imex:IM-16880-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:1c, S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain)	-	2011/09/22	2014/10/16	rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:1A4DA07451284D99|rigid:RvJ7lBTIh7Tj/GCta+Ug3H8bJto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08722	uniprotkb:Q8CGU4	intact:EBI-4404185	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409279|imex:IM-16880-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:1c, S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain)	-	2011/09/22	2014/10/16	rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:2E4ABA7D42E4C2FF|rigid:RvJ7lBTIh7Tj/GCta+Ug3H8bJto	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:Q8K1S3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-4396886|uniprotkb:Q3U4F2|uniprotkb:Q6PFH0|uniprotkb:Q80Y85|uniprotkb:Q9D398|ensembl:ENSMUSP00000077080	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_mouse(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409602|imex:IM-16880-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_084046.2|refseq:XP_006513091.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:1WMG|rcsb pdb:6OOL|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSMUSG00000020099(gene)|ensembl:ENSMUST00000077925(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)	-	-	-	figure legend:3b|comment:The presence of FynA is required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2011/09/22	2014/10/16	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:YqYcFUZ3Y3spL702w6mshOPjNf410090	intact-crc:2B3EE49381FE6D5C|rigid:sYqPA6tHFBIImj/0X1WkQOiOuho	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:P70211	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409645|imex:IM-16880-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889	-	-	-	figure legend:S2c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2011/09/22	2014/10/16	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090	intact-crc:AC6A52835509B956|rigid:oWFxYlVb1gAyNElh188MPJl7vs0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CGU4	uniprotkb:O08722	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	intact:EBI-4404185	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409293|imex:IM-16880-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft)	go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)	-	-	figure legend:1d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2011/09/22	2014/10/16	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116	intact-crc:3208BD23C05DBF8C|rigid:RvJ7lBTIh7Tj/GCta+Ug3H8bJto	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q63155	uniprotkb:Q8CGU4	intact:EBI-1798965	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409624|imex:IM-16880-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:S2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/09/22	2014/10/16	rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	intact-crc:A6490663B398E4DE|rigid:Xcuxg1Fwk66ZZGV+7IrIZIFZuO4	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IZJ1	uniprotkb:Q63155	intact:EBI-4409075|uniprotkb:Q5T3R9|uniprotkb:Q5T3S0|uniprotkb:Q86SN3|uniprotkb:Q8N1Y2|uniprotkb:Q9H9F3|ensembl:ENSP00000334329	intact:EBI-1798965	psi-mi:unc5b_human(display_long)|uniprotkb:UNC5B(gene name)|psi-mi:UNC5B(display_short)|uniprotkb:P53RDL1(gene name synonym)|uniprotkb:UNC5H2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym)|uniprotkb:p53-regulated receptor for death and life protein 1(gene name synonym)|uniprotkb:UNQ1883/PRO4326(orf name)	psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (2008)	pubmed:18469807|imex:IM-16880	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-4409656|imex:IM-16880-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_734465.2|refseq:NP_001231818.1|dip:DIP-46275N|ensembl:ENSG00000107731(gene)|ensembl:ENST00000335350(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|reactome:R-HSA-373752|reactome:R-HSA-418886|reactome:R-HSA-418889	rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3	-	-	-	figure legend:S2d|agonist:The presence of either netrin-1, Fyn or GFP-agap2 is required for the interaction to happen.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/09/22	2014/10/16	rogid:qgsg0FKcvNzdgB6RcnV9LKwPMbY9606	rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116	intact-crc:5D55AB3579621670|rigid:utcmBBE22aiUgGCTU67+ODfs4rQ	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)