#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q17392	uniprotkb:Q21554	intact:EBI-2416331|uniprotkb:Q20428|ensemblmetazoa:F45E12.3.1	intact:EBI-325461|ensemblmetazoa:M18.5.1|ensemblmetazoa:M18.5.2	psi-mi:cul4_caeel(display_long)|uniprotkb:F45E12.3(orf name)|uniprotkb:cul-4(gene name)|psi-mi:cul-4(display_short)	psi-mi:ddb1_caeel(display_long)|uniprotkb:M18.5(orf name)|uniprotkb:ddb-1(gene name)|psi-mi:ddb-1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kim et al. (2007)	pubmed:17145765|imex:IM-16972	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3899233|imex:IM-16972-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|refseq:NP_495525.2|wormbase:F45E12.3|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|reactome:R-CEL-8951664|reactome:R-CEL-110314|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-CEL-5696394|ensemblmetazoa:F45E12.3.1(transcript)|ensemblmetazoa:WBGene00000839(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	reactome:R-CEL-5696394|refseq:NP_502299.1|wormbase:M18.5|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|ensemblmetazoa:M18.5.1(transcript)|ensemblmetazoa:M18.5.2(transcript)|ensemblmetazoa:WBGene00010890(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035861"(site of double-strand break)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-25884N|reactome:R-CEL-8951664|reactome:R-CEL-110314	-	-	-	figure legend:Fig 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/12	2014/10/16	rogid:2512Q+RwT10wqCSrhCG5l8o4Agk6239	rogid:uwIp7vn4UuHW3sAFxcgP2Fj5ZVU6239	intact-crc:77344AF7267F3311|rigid:pQvHbHetP6xtOVC3RXsB83XxeMY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86S68	uniprotkb:Q21554	intact:EBI-3902879|ensemblmetazoa:Y54E10A.15.1	intact:EBI-325461|ensemblmetazoa:M18.5.1|ensemblmetazoa:M18.5.2	psi-mi:q86s68_caeel(display_long)|uniprotkb:Y54E10A.15(orf name)|uniprotkb:cdt-1(gene name)|psi-mi:cdt-1(display_short)|uniprotkb:CELE_Y54E10A.15(orf name)	psi-mi:ddb1_caeel(display_long)|uniprotkb:M18.5(orf name)|uniprotkb:ddb-1(gene name)|psi-mi:ddb-1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2007)	pubmed:17145765|imex:IM-16972	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3902878|imex:IM-16972-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036390|reactome:R-CEL-68949|interpro:IPR014939(DNA replication factor CDT1-like)|refseq:NP_001040707.1|wormbase:Y54E10A.15|interpro:IPR032054|ensemblmetazoa:WBGene00000413(gene)|ensemblmetazoa:Y54E10A.15.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-68962|interpro:IPR038090	reactome:R-CEL-5696394|refseq:NP_502299.1|wormbase:M18.5|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|ensemblmetazoa:M18.5.1(transcript)|ensemblmetazoa:M18.5.2(transcript)|ensemblmetazoa:WBGene00010890(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035861"(site of double-strand break)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-25884N|reactome:R-CEL-8951664|reactome:R-CEL-110314	-	-	-	figure legend:Fig 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/05/12	2014/10/16	rogid:QK1s2+ecB78fETotgKLzn7M4Wrc6239	rogid:uwIp7vn4UuHW3sAFxcgP2Fj5ZVU6239	intact-crc:FE157DD9F72B020B|rigid:GzxH/w0ODWBd3rK8XW0en71IU3I	false	green fluorescent protein tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q21554	uniprotkb:Q86S68	intact:EBI-325461|ensemblmetazoa:M18.5.1|ensemblmetazoa:M18.5.2	intact:EBI-3902879|ensemblmetazoa:Y54E10A.15.1	psi-mi:ddb1_caeel(display_long)|uniprotkb:M18.5(orf name)|uniprotkb:ddb-1(gene name)|psi-mi:ddb-1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)	psi-mi:q86s68_caeel(display_long)|uniprotkb:Y54E10A.15(orf name)|uniprotkb:cdt-1(gene name)|psi-mi:cdt-1(display_short)|uniprotkb:CELE_Y54E10A.15(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17145765|imex:IM-16972	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3902897|imex:IM-16972-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-5696394|refseq:NP_502299.1|wormbase:M18.5|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|ensemblmetazoa:M18.5.1(transcript)|ensemblmetazoa:M18.5.2(transcript)|ensemblmetazoa:WBGene00010890(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035861"(site of double-strand break)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-25884N|reactome:R-CEL-8951664|reactome:R-CEL-110314	interpro:IPR036390|reactome:R-CEL-68949|interpro:IPR014939(DNA replication factor CDT1-like)|refseq:NP_001040707.1|wormbase:Y54E10A.15|interpro:IPR032054|ensemblmetazoa:WBGene00000413(gene)|ensemblmetazoa:Y54E10A.15.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-68962|interpro:IPR038090	-	-	-	figure legend:Fig 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/05/12	2014/10/16	rogid:uwIp7vn4UuHW3sAFxcgP2Fj5ZVU6239	rogid:QK1s2+ecB78fETotgKLzn7M4Wrc6239	intact-crc:B691903B09DF8A76|rigid:GzxH/w0ODWBd3rK8XW0en71IU3I	false	flag tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86S68	uniprotkb:Q21554	intact:EBI-3902879|ensemblmetazoa:Y54E10A.15.1	intact:EBI-325461|ensemblmetazoa:M18.5.1|ensemblmetazoa:M18.5.2	psi-mi:q86s68_caeel(display_long)|uniprotkb:Y54E10A.15(orf name)|uniprotkb:cdt-1(gene name)|psi-mi:cdt-1(display_short)|uniprotkb:CELE_Y54E10A.15(orf name)	psi-mi:ddb1_caeel(display_long)|uniprotkb:M18.5(orf name)|uniprotkb:ddb-1(gene name)|psi-mi:ddb-1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2007)	pubmed:17145765|imex:IM-16972	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3902913|imex:IM-16972-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036390|reactome:R-CEL-68949|interpro:IPR014939(DNA replication factor CDT1-like)|refseq:NP_001040707.1|wormbase:Y54E10A.15|interpro:IPR032054|ensemblmetazoa:WBGene00000413(gene)|ensemblmetazoa:Y54E10A.15.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-68962|interpro:IPR038090	reactome:R-CEL-5696394|refseq:NP_502299.1|wormbase:M18.5|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|ensemblmetazoa:M18.5.1(transcript)|ensemblmetazoa:M18.5.2(transcript)|ensemblmetazoa:WBGene00010890(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035861"(site of double-strand break)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-25884N|reactome:R-CEL-8951664|reactome:R-CEL-110314	-	-	-	figure legend:Fig 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/05/12	2014/10/16	rogid:QK1s2+ecB78fETotgKLzn7M4Wrc6239	rogid:uwIp7vn4UuHW3sAFxcgP2Fj5ZVU6239	intact-crc:25D3A97DAC499A5F|rigid:GzxH/w0ODWBd3rK8XW0en71IU3I	false	glutathione s tranferase tag:?-?	flag tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)