#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14526 uniprotkb:Q13363 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stankovic-Valentin et al. (2006) pubmed:16762039 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5238480 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700 - - - figure legend:2A and B|curation depth:mimix curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2011/10/31 2014/10/16 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 intact-crc:104A8C88A2A12386|rigid:39hNvKUt+CIAgEiG2iDqLAo2ZeE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14526 uniprotkb:O88712 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stankovic-Valentin et al. (2006) pubmed:16762039 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5238503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N - - - figure legend:2C|curation depth:mimix curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/10/31 2014/10/16 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 intact-crc:ADF422B0906C0A6B|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14526 uniprotkb:P56546 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269 psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stankovic-Valentin et al. (2006) pubmed:16762039 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5238627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265 - - - figure legend:2C , 3B and 4C|curation depth:mimix curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/10/31 2014/10/16 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090 intact-crc:49491F8687D407A0|rigid:OxgzBEKEaB5K2sbFMsSkS6V3ahQ false mutation disrupting interaction:244-244 mutation disrupting interaction:58-58|mutation disrupting interaction:72-72 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88712 uniprotkb:Q14526 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stankovic-Valentin et al. (2006) pubmed:16762039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5238515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:1D and 4B|curation depth:mimix curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2011/10/31 2014/10/16 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:5A357C99101D122C|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false - mutation disrupting interaction:244-244 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P56546 uniprotkb:Q14526 intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0018"(two hybrid) Stankovic-Valentin et al. (2006) pubmed:16762039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5238608 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265 ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:3A|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/10/31 2014/10/16 rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:9BB7D75529A49D7C|rigid:OxgzBEKEaB5K2sbFMsSkS6V3ahQ false mutation disrupting interaction:58-58|mutation disrupting interaction:72-72 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88712 uniprotkb:Q14526 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0018"(two hybrid) Stankovic-Valentin et al. (2006) pubmed:16762039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5238669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:4A|curation depth:mimix curation taxid:9986(rabit-rk13)|taxid:9986(rk13 cell line originating from rabbit kidney epithelial cells) - 2011/10/31 2014/10/16 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:3F18C49B82F2AD90|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false - mutation disrupting interaction:244-244 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)