#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q80Z30	uniprotkb:P05065	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-522118|uniprotkb:Q63038|ensembl:ENSRNOP00000068764|ensembl:ENSRNOP00000069507|ensembl:ENSRNOP00000069540	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:aldoa_rat(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)	psi-mi:"MI:0047"(far western blotting)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473090|mint:MINT-8247250	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247253(identity)	rgd:2089|refseq:NP_001170776.1|refseq:NP_036627.1|ensembl:ENSRNOG00000052802(gene)|ensembl:ENSRNOT00000080988(transcript)|ensembl:ENSRNOT00000087928(transcript)|ensembl:ENSRNOT00000088473(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05065|reactome:R-RNO-114608|reactome:R-RNO-6798695|reactome:R-RNO-70171|reactome:R-RNO-70263|refseq:XP_006230273.1|refseq:NP_001258465.1|mint:MINT-8247252(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	comment:mint|figure legend:F1; T1|partial coverage:partial coverage	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:dUcYtyffbl8dC/1SD/ZtEtiFyB010116	intact-crc:1BB4C3B3D1DFB8DE|rigid:mt6PckxrLRO8kIcOK+eRIhLnPiM	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q80Z30	uniprotkb:P04797	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473098|mint:MINT-8247264	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247267(identity)	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1|mint:MINT-8247266(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	comment:mint|figure legend:F1; T1;F2|partial coverage:partial coverage	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	intact-crc:E09178E5087D34C1|rigid:XjEIW7v6Y3IPo3w4roV1EyIJgw8	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q80Z30	uniprotkb:P04797	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473118|mint:MINT-8247281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247284(identity)	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1|mint:MINT-8247283(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	figure legend:F3|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	intact-crc:4206497E9CB62056|rigid:XjEIW7v6Y3IPo3w4roV1EyIJgw8	false	-	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q80Z30	uniprotkb:P05065	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-522118|uniprotkb:Q63038|ensembl:ENSRNOP00000068764|ensembl:ENSRNOP00000069507|ensembl:ENSRNOP00000069540	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:aldoa_rat(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473126|mint:MINT-8247293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247296(identity)	rgd:2089|refseq:NP_001170776.1|refseq:NP_036627.1|ensembl:ENSRNOG00000052802(gene)|ensembl:ENSRNOT00000080988(transcript)|ensembl:ENSRNOT00000087928(transcript)|ensembl:ENSRNOT00000088473(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05065|reactome:R-RNO-114608|reactome:R-RNO-6798695|reactome:R-RNO-70171|reactome:R-RNO-70263|refseq:XP_006230273.1|refseq:NP_001258465.1|mint:MINT-8247295(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	figure legend:F3|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:dUcYtyffbl8dC/1SD/ZtEtiFyB010116	intact-crc:98AD1F0BA8B080BA|rigid:mt6PckxrLRO8kIcOK+eRIhLnPiM	false	-	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q80Z30	uniprotkb:P04797	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473146|mint:MINT-8247304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247306(identity)	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1|mint:MINT-8247307(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	figure legend:F4|comment:mint|partial coverage:partial coverage	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	intact-crc:CEC99A4832A61950|rigid:XjEIW7v6Y3IPo3w4roV1EyIJgw8	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q80Z30	uniprotkb:P04797	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473182|mint:MINT-8247331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247334(identity)	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1|mint:MINT-8247333(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	figure legend:F5|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	intact-crc:0B0E1C441E5FC00F|rigid:XjEIW7v6Y3IPo3w4roV1EyIJgw8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q80Z30	uniprotkb:P04797	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473190|mint:MINT-8247338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247341(identity)	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1|mint:MINT-8247340(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	-	figure legend:F5|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	intact-crc:D8BFA2DD55FACAB4|rigid:XjEIW7v6Y3IPo3w4roV1EyIJgw8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q63450	uniprotkb:Q80Z30	intact:EBI-7007884|ensembl:ENSRNOP00000033456|intact:MINT-3375300|uniprotkb:Q63084	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	psi-mi:kcc1a_rat(display_long)|uniprotkb:Camk1(gene name)|psi-mi:Camk1(display_short)|uniprotkb:CaM kinase I(gene name synonym)|uniprotkb:CaM kinase I alpha(gene name synonym)	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473210|mint:MINT-8247563	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006237065.1|ensembl:ENSRNOG00000021781(gene)|ensembl:ENSRNOT00000029728(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0060143"(positive regulation of syncytium formation by plasma membrane fusion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63450|rcsb pdb:1A06|rcsb pdb:1MXE|rcsb pdb:2L7L|reactome:R-RNO-9619229|refseq:NP_604463.1|rgd:629473|mint:MINT-8247566(identity)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247565(identity)	-	function:"Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes like transcriptional regulation, hormone production, translational regulation, regulation of actin filament organization and neurite outgrowth. Involved in calcium-dependent activation of the ERK pathway (By similarity). Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]-x(3)-[MVLIF]. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CTFR, MYL9, SYN1/synapsin I and SYNII/synapsin II"|comment:mint	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	figure legend:F9|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:7KJ2wmUk+WzmKMUkzS52jSWZ54w10116	rogid:QavUuz5v5U452KObShuPIhsM02I10116	intact-crc:EAFB4CB9ED8BF2A6|rigid:m5IlQuCOFeu17XRYDgpIEZ2Xaao	false	-	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q80Z30	uniprotkb:P08414	intact:EBI-7473061|intact:MINT-4601785|ensembl:ENSRNOP00000003859	intact:EBI-7473222|intact:MINT-4099615|uniprotkb:Q61381	psi-mi:ppm1e_rat(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:Camkn(gene name synonym)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)	psi-mi:kcc4_mouse(display_long)|uniprotkb:Camk4(gene name)|psi-mi:Camk4(display_short)|uniprotkb:CaM kinase-GR(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Ishida et al. (2005)	doi:10.1016/j.abb.2004.11.022|pubmed:15680915|mint:MINT-8224023	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7473218|mint:MINT-8247598	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:735028|refseq:NP_942068.1|ensembl:ENSRNOG00000024730(gene)|ensembl:ENSRNOT00000003859(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-8247600(identity)	mint:P08414|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0001650"(fibrillar center)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-111932|reactome:R-MMU-442729|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006913"(nucleocytoplasmic transport)|interpro:IPR000719(Protein kinase, core)|mint:MINT-8247601(identity)	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Inactivates multifunctional CaM kinases	comment:mint|function:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May be involved in transcriptional regulation. May be involved in regulation of microtubule dynamics. In vitro, phosphorylates CREB1, CREBBP, PRM2, MEF2A, MEF2D and STMN1/OP18. May be involved in spermatogenesis. May play a role in the consolidation/retention of hippocampus-dependent long-term memory	figure legend:F7|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/20	2014/10/16	rogid:QavUuz5v5U452KObShuPIhsM02I10116	rogid:ohNFWBbyCjZ17efJL3Thgb1XzDY10090	intact-crc:178D38DAEBB4512C|rigid:vp7rVl4ywt8z2KHGbr5Pt6FCcRU	false	-	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)