#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O44326 uniprotkb:Q967F4 intact:EBI-317320|ensemblmetazoa:K05C4.6a.1|ensemblmetazoa:K05C4.6a.2 intact:EBI-2528888|uniprotkb:O44327|ensemblmetazoa:W02B9.1b.1|ensemblmetazoa:W02B9.1b.2|uniprotkb:B2MZC5|uniprotkb:H2FLJ9|uniprotkb:H2FLK0 psi-mi:hmp2_caeel(display_long)|uniprotkb:hmp-2(gene name)|psi-mi:hmp-2(display_short)|uniprotkb:Protein humpback-2(gene name synonym)|uniprotkb:K05C4.6(orf name) psi-mi:hmr1_caeel(display_long)|uniprotkb:hmr-1(gene name)|psi-mi:hmr-1(display_short)|uniprotkb:Protein Hammerhead(gene name synonym)|uniprotkb:W02B9.1(orf name) psi-mi:"MI:0018"(two hybrid) Pettitt et al. (2003) pubmed:12847081|imex:IM-17193 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3896154|imex:IM-17193-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:K05C4.6a|reactome:R-CEL-8853884|refseq:NP_001252426.1|rcsb pdb:4R0Z|rcsb pdb:4R10|rcsb pdb:4R11|rcsb pdb:5XA5|interpro:IPR016024(Armadillo-type fold)|ensemblmetazoa:K05C4.6a.1(transcript)|ensemblmetazoa:K05C4.6a.2(transcript)|ensemblmetazoa:WBGene00001979(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|reactome:R-CEL-6798695|reactome:R-CEL-351906|reactome:R-CEL-525793|reactome:R-CEL-8980692|reactome:R-CEL-9013406|reactome:R-CEL-9013407|dip:DIP-27261N|reactome:R-CEL-195253|reactome:R-CEL-196299|reactome:R-CEL-201681|reactome:R-CEL-201722|reactome:R-CEL-3134973|reactome:R-CEL-3769402|reactome:R-CEL-4086398|reactome:R-CEL-5218920|reactome:R-CEL-6809371|reactome:R-CEL-8951430 ensemblmetazoa:W02B9.1b.1(transcript)|ensemblmetazoa:W02B9.1b.2(transcript)|ensemblmetazoa:WBGene00001980(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018247|interpro:IPR020894|rcsb pdb:4R10|rcsb pdb:4R11|interpro:IPR000742(EGF-like, type 3)|refseq:NP_001021650.1|wormbase:W02B9.1a|wormbase:W02B9.1b|wormbase:W02B9.1d|wormbase:W02B9.1c|wormbase:W02B9.1e|refseq:NP_001021649.2|refseq:NP_001129794.1|refseq:NP_001251561.1|refseq:NP_001251562.1|dip:DIP-56285N - - - figure legend:Fig 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/05/11 2014/10/16 rogid:8DLyhATsxCZq1Vthd5haUE54Kmw6239 rogid:ogbuiUw6rS5+SMw515Bday0fg246239 intact-crc:8CA963306E1AA8DF|rigid:ev3Gecv0RWZ87bpfqg6J4pGOq6w false sufficient binding region:13..13-678..678 sufficient binding region:2801..2801-2920..2920 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9U308 uniprotkb:Q967F4 intact:EBI-2917356|ensemblmetazoa:Y105C5B.21a.1|uniprotkb:Q2HQL5 intact:EBI-2528888|uniprotkb:O44327|ensemblmetazoa:W02B9.1b.1|ensemblmetazoa:W02B9.1b.2|uniprotkb:B2MZC5|uniprotkb:H2FLJ9|uniprotkb:H2FLK0 psi-mi:jac1_caeel(display_long)|uniprotkb:jac-1(gene name)|psi-mi:jac-1(display_short)|uniprotkb:p120 catenin homolog(gene name synonym)|uniprotkb:Y105C5B.21(orf name) psi-mi:hmr1_caeel(display_long)|uniprotkb:hmr-1(gene name)|psi-mi:hmr-1(display_short)|uniprotkb:Protein Hammerhead(gene name synonym)|uniprotkb:W02B9.1(orf name) psi-mi:"MI:0018"(two hybrid) Pettitt et al. (2003) pubmed:12847081|imex:IM-17193 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3896144|imex:IM-17193-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00002175(gene)|ensemblmetazoa:Y105C5B.21a.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016342"(catenin complex)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028446|interpro:IPR036116|go:"GO:0005634"(nucleus)|refseq:NP_001041007.1|refseq:NP_001041008.1|wormbase:Y105C5B.21a|wormbase:Y105C5B.21b|reactome:R-CEL-6798695|reactome:R-CEL-351906|dip:DIP-61637N|reactome:R-CEL-5218920|reactome:R-CEL-6809371 ensemblmetazoa:W02B9.1b.1(transcript)|ensemblmetazoa:W02B9.1b.2(transcript)|ensemblmetazoa:WBGene00001980(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018247|interpro:IPR020894|rcsb pdb:4R10|rcsb pdb:4R11|interpro:IPR000742(EGF-like, type 3)|refseq:NP_001021650.1|wormbase:W02B9.1a|wormbase:W02B9.1b|wormbase:W02B9.1d|wormbase:W02B9.1c|wormbase:W02B9.1e|refseq:NP_001021649.2|refseq:NP_001129794.1|refseq:NP_001251561.1|refseq:NP_001251562.1|dip:DIP-56285N - - - figure legend:Fig 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/05/11 2014/10/16 rogid:cIOmwpEB/BbWu+pT6cqB2/+b9AQ6239 rogid:ogbuiUw6rS5+SMw515Bday0fg246239 intact-crc:0658BB8F21BC198A|rigid:BCN+szPJN+lk8HGMEyJqvBj6Hfo false sufficient binding region:733..733-1254..1254 necessary binding region:2829-2831|sufficient binding region:2801..2801-2920..2920 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q967F4 uniprotkb:Q9U308 intact:EBI-2528888|uniprotkb:O44327|ensemblmetazoa:W02B9.1b.1|ensemblmetazoa:W02B9.1b.2|uniprotkb:B2MZC5|uniprotkb:H2FLJ9|uniprotkb:H2FLK0 intact:EBI-2917356|ensemblmetazoa:Y105C5B.21a.1|uniprotkb:Q2HQL5 psi-mi:hmr1_caeel(display_long)|uniprotkb:hmr-1(gene name)|psi-mi:hmr-1(display_short)|uniprotkb:Protein Hammerhead(gene name synonym)|uniprotkb:W02B9.1(orf name) psi-mi:jac1_caeel(display_long)|uniprotkb:jac-1(gene name)|psi-mi:jac-1(display_short)|uniprotkb:p120 catenin homolog(gene name synonym)|uniprotkb:Y105C5B.21(orf name) psi-mi:"MI:0663"(confocal microscopy) Pettitt et al. (2003) pubmed:12847081|imex:IM-17193 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3896207|imex:IM-17193-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:W02B9.1b.1(transcript)|ensemblmetazoa:W02B9.1b.2(transcript)|ensemblmetazoa:WBGene00001980(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018247|interpro:IPR020894|rcsb pdb:4R10|rcsb pdb:4R11|interpro:IPR000742(EGF-like, type 3)|refseq:NP_001021650.1|wormbase:W02B9.1a|wormbase:W02B9.1b|wormbase:W02B9.1d|wormbase:W02B9.1c|wormbase:W02B9.1e|refseq:NP_001021649.2|refseq:NP_001129794.1|refseq:NP_001251561.1|refseq:NP_001251562.1|dip:DIP-56285N ensemblmetazoa:WBGene00002175(gene)|ensemblmetazoa:Y105C5B.21a.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016342"(catenin complex)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028446|interpro:IPR036116|go:"GO:0005634"(nucleus)|refseq:NP_001041007.1|refseq:NP_001041008.1|wormbase:Y105C5B.21a|wormbase:Y105C5B.21b|reactome:R-CEL-6798695|reactome:R-CEL-351906|dip:DIP-61637N|reactome:R-CEL-5218920|reactome:R-CEL-6809371 go:"GO:0005912"(adherens junction) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo) - 2011/05/11 2014/10/16 rogid:ogbuiUw6rS5+SMw515Bday0fg246239 rogid:cIOmwpEB/BbWu+pT6cqB2/+b9AQ6239 intact-crc:FD27C979B01972AF|rigid:BCN+szPJN+lk8HGMEyJqvBj6Hfo false - green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)