#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8CBF3	uniprotkb:Q14451	intact:EBI-4288051|uniprotkb:B1B1C2|uniprotkb:Q3UY27|uniprotkb:Q6PG23|uniprotkb:Q8CBE2|ensembl:ENSMUSP00000035129	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	psi-mi:ephb1_mouse(display_long)|uniprotkb:Ephb1(gene name)|psi-mi:Ephb1(display_short)	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Han et al. (2002)	pubmed:12223469|mint:MINT-6731491	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4288047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161768.1|refseq:NP_775623.3|ensembl:ENSMUSG00000032537(gene)|go:"GO:0032433"(filopodium tip)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|go:"GO:1902725"(negative regulation of satellite cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0031901"(early endosome membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034231|interpro:IPR036116|interpro:IPR042819|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|ensembl:ENSMUST00000035129(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0016020"(membrane)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022008"(neurogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031589"(cell-substrate adhesion)	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	-	-	-	figure legend:fig4|curation depth:mimix curation	taxid:10090(mouse-p19)|taxid:10090(Mus musculus embryonic teratocarcinoma cell line,  epithelial-like, induced by retinoic acid)	-	2011/06/20	2014/10/16	rogid:M/8yJmcnxHw9XrFVWs5oHmpRbzo10090	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	intact-crc:136939A7DF195C1E|rigid:4G+tdcMEJnOyCYhNqFflLARM4f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14451	uniprotkb:P54762	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	intact:EBI-80252|uniprotkb:A8K593|uniprotkb:Q0VG87|uniprotkb:O43569|uniprotkb:O95142|uniprotkb:O95143|ensembl:ENSP00000381097|uniprotkb:B3KTB2|uniprotkb:B5A969	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:ephb1_human(display_long)|uniprotkb:EPHB1(gene name)|psi-mi:EPHB1(display_short)|uniprotkb:EPHT2(gene name synonym)|uniprotkb:NET(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH-2(gene name synonym)|uniprotkb:HEK6(gene name synonym)|uniprotkb:ELK(gene name synonym)|uniprotkb:EPH-like kinase 6(gene name synonym)|uniprotkb:EPH tyrosine kinase 2(gene name synonym)|uniprotkb:Neuronally-expressed EPH-related tyrosine kinase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Han et al. (2002)	pubmed:12223469|mint:MINT-6731491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4304359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|ensembl:ENSG00000154928(gene)|ensembl:ENST00000398015(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|go:"GO:1902725"(negative regulation of satellite cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034231|interpro:IPR036116|interpro:IPR042819|rcsb pdb:2DJS|rcsb pdb:2EAO|rcsb pdb:3ZFX|rcsb pdb:5MJA|rcsb pdb:5MJB|rcsb pdb:6UMW|rcsb pdb:7KPL|rcsb pdb:7KPM|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004432.1	-	-	-	figure legend:fig1.|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/06/20	2014/10/16	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	rogid:o3NRwvWL2GQwOZlirn1qoW1VfyA9606	intact-crc:F6CDCEB9BDF8AEA1|rigid:9tWsaPtXDiNvfX66p7gm10VvekQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54762	uniprotkb:Q14451	intact:EBI-80252|uniprotkb:A8K593|uniprotkb:Q0VG87|uniprotkb:O43569|uniprotkb:O95142|uniprotkb:O95143|ensembl:ENSP00000381097|uniprotkb:B3KTB2|uniprotkb:B5A969	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	psi-mi:ephb1_human(display_long)|uniprotkb:EPHB1(gene name)|psi-mi:EPHB1(display_short)|uniprotkb:EPHT2(gene name synonym)|uniprotkb:NET(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH-2(gene name synonym)|uniprotkb:HEK6(gene name synonym)|uniprotkb:ELK(gene name synonym)|uniprotkb:EPH-like kinase 6(gene name synonym)|uniprotkb:EPH tyrosine kinase 2(gene name synonym)|uniprotkb:Neuronally-expressed EPH-related tyrosine kinase(gene name synonym)	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Han et al. (2002)	pubmed:12223469|mint:MINT-6731491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4287913	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|ensembl:ENSG00000154928(gene)|ensembl:ENST00000398015(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|go:"GO:1902725"(negative regulation of satellite cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034231|interpro:IPR036116|interpro:IPR042819|rcsb pdb:2DJS|rcsb pdb:2EAO|rcsb pdb:3ZFX|rcsb pdb:5MJA|rcsb pdb:5MJB|rcsb pdb:6UMW|rcsb pdb:7KPL|rcsb pdb:7KPM|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004432.1	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	-	-	-	figure legend:fig1.|curation depth:mimix curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2011/06/20	2014/10/16	rogid:o3NRwvWL2GQwOZlirn1qoW1VfyA9606	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	intact-crc:B1C74A448D4669A9|rigid:9tWsaPtXDiNvfX66p7gm10VvekQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14451	uniprotkb:P54762	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	intact:EBI-80252|uniprotkb:A8K593|uniprotkb:Q0VG87|uniprotkb:O43569|uniprotkb:O95142|uniprotkb:O95143|ensembl:ENSP00000381097|uniprotkb:B3KTB2|uniprotkb:B5A969	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:ephb1_human(display_long)|uniprotkb:EPHB1(gene name)|psi-mi:EPHB1(display_short)|uniprotkb:EPHT2(gene name synonym)|uniprotkb:NET(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH-2(gene name synonym)|uniprotkb:HEK6(gene name synonym)|uniprotkb:ELK(gene name synonym)|uniprotkb:EPH-like kinase 6(gene name synonym)|uniprotkb:EPH tyrosine kinase 2(gene name synonym)|uniprotkb:Neuronally-expressed EPH-related tyrosine kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2002)	pubmed:12223469|mint:MINT-6731491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4287988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|ensembl:ENSG00000154928(gene)|ensembl:ENST00000398015(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|go:"GO:1902725"(negative regulation of satellite cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034231|interpro:IPR036116|interpro:IPR042819|rcsb pdb:2DJS|rcsb pdb:2EAO|rcsb pdb:3ZFX|rcsb pdb:5MJA|rcsb pdb:5MJB|rcsb pdb:6UMW|rcsb pdb:7KPL|rcsb pdb:7KPM|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004432.1	-	-	-	figure legend:fig3.|curation depth:mimix curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2011/06/20	2014/10/16	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	rogid:o3NRwvWL2GQwOZlirn1qoW1VfyA9606	intact-crc:A629DF68A0BD8A6E|rigid:9tWsaPtXDiNvfX66p7gm10VvekQ	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14451	uniprotkb:P54762	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	intact:EBI-80252|uniprotkb:A8K593|uniprotkb:Q0VG87|uniprotkb:O43569|uniprotkb:O95142|uniprotkb:O95143|ensembl:ENSP00000381097|uniprotkb:B3KTB2|uniprotkb:B5A969	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:ephb1_human(display_long)|uniprotkb:EPHB1(gene name)|psi-mi:EPHB1(display_short)|uniprotkb:EPHT2(gene name synonym)|uniprotkb:NET(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH-2(gene name synonym)|uniprotkb:HEK6(gene name synonym)|uniprotkb:ELK(gene name synonym)|uniprotkb:EPH-like kinase 6(gene name synonym)|uniprotkb:EPH tyrosine kinase 2(gene name synonym)|uniprotkb:Neuronally-expressed EPH-related tyrosine kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2002)	pubmed:12223469|mint:MINT-6731491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-4288026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|ensembl:ENSG00000154928(gene)|ensembl:ENST00000398015(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|go:"GO:1902725"(negative regulation of satellite cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034231|interpro:IPR036116|interpro:IPR042819|rcsb pdb:2DJS|rcsb pdb:2EAO|rcsb pdb:3ZFX|rcsb pdb:5MJA|rcsb pdb:5MJB|rcsb pdb:6UMW|rcsb pdb:7KPL|rcsb pdb:7KPM|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|refseq:NP_004432.1	-	-	-	figure legend:fig2.|curation depth:mimix curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2011/06/20	2014/10/16	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	rogid:o3NRwvWL2GQwOZlirn1qoW1VfyA9606	intact-crc:64EF303DAE45CBA1|rigid:9tWsaPtXDiNvfX66p7gm10VvekQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)