#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O88712 uniprotkb:Q14526 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0018"(two hybrid) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5236767|imex:IM-16913-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/10/26 2014/10/16 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:94BFDD7AEE3B53D6|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false - sufficient binding region:154-315 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14526 uniprotkb:Q14526 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0018"(two hybrid) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5236813|imex:IM-16913-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/10/26 2014/10/16 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:9DE25225E74545D4|rigid:vWEOjreDiPNFxmJLiqzuKBJw604 false sufficient binding region:20-159(IPR000210) sufficient binding region:20-159(IPR000210) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88712 uniprotkb:Q14526 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0018"(two hybrid) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5236797|imex:IM-16913-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:3B|comment:A HIC1 bait construct including the BTB/POZ domain shows only a low interaction probably due to a masked CtB1 interaction motif.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9986(rabit-rk13)|taxid:9986(rk13 cell line originating from rabbit kidney epithelial cells) - 2011/10/26 2014/10/16 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:92B093DB7CB1BC6E|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false - necessary binding region:241-247 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88712 uniprotkb:Q14526 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0096"(pull down) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5236843|imex:IM-16913-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 - - - figure legend:5A|comment:mCtBP1 interacts with Flag-HIC1 but not with Flag-HIC1 Delta-GLDLSKK.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/10/26 2014/10/16 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:93687819C804995B|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false glutathione s tranferase tag:?-? necessary binding region:241-247|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14526 uniprotkb:O88712 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5236870|imex:IM-16913-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N - - - figure legend:5B|comment:mCtBP1 protein specifically interacts with the HIC1 Delta-GLDLSKK protein, albeit with a much lower affinity than with the full-length HIC1 protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/10/26 2014/10/16 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 intact-crc:C135571B5A89AC55|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:G3HK86 uniprotkb:Q14526 intact:EBI-5259083 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:g3hk86_crigr(display_long)|uniprotkb:I79_011104(orf name) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5259093|imex:IM-16913-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR036291|interpro:IPR043322|interpro:IPR029752|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0051287"(NAD binding) ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 go:"GO:0005634"(nucleus) - - figure legend:7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-ecr-cho)|taxid:10029(Cricetulus griseus EcR-CHO cell line) - 2011/10/26 2014/10/16 rogid:FAsdbQu04HTPY8Cz3AXTTR7IKfo10029 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:326AB414DA8933E5|rigid:D+9LlmASygj6NvDlRHDxZ7EjUkA false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88712 uniprotkb:Q14526 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 intact:EBI-2507362|ensembl:ENSP00000314080|uniprotkb:D3DTI4 psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:hic1_human(display_long)|uniprotkb:HIC1(gene name)|psi-mi:HIC1(display_short)|uniprotkb:ZBTB29(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 29(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Deltour et al. (2002) pubmed:12052894|imex:IM-16913 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-5236887|imex:IM-16913-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N ensembl:ENSG00000177374(gene)|ensembl:ENST00000322941(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028424|interpro:IPR036236|mint:Q14526|reactome:R-HSA-3232118|refseq:NP_001091672.1|refseq:NP_006488.2 go:"GO:0005634"(nucleus) - - figure legend:6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/10/26 2014/10/16 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 rogid:+FU3xu1r+vneOHeXlJmvy1CFeVA9606 intact-crc:83465E7656757772|rigid:uomcVQ3D52bs94/d7VD+H36KsGE false - flag tag:?-?|necessary binding region:241-247 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)