#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q10953 uniprotkb:Q10666 intact:EBI-2530558|uniprotkb:O16145|ensemblmetazoa:B0336.1a.1|ensemblmetazoa:B0336.1a.2 intact:EBI-317870|uniprotkb:O45007|ensemblmetazoa:W10C8.2.1 psi-mi:wrm1_caeel(display_long)|uniprotkb:wrm-1(gene name)|psi-mi:wrm-1(display_short)|uniprotkb:Worm armadillo protein 1(gene name synonym)|uniprotkb:B0336.1(orf name) psi-mi:pop1_caeel(display_long)|uniprotkb:pop-1(gene name)|psi-mi:pop-1(display_short)|uniprotkb:W10C8.2(orf name)|uniprotkb:Posterior pharynx defect protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Natarajan et al. (2001) pubmed:11560894|imex:IM-16907|mint:MINT-5214547 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3831797|imex:IM-16907-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0336.1a.1(transcript)|ensemblmetazoa:B0336.1a.2(transcript)|ensemblmetazoa:WBGene00006943(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042661"(regulation of mesodermal cell fate specification)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044332"(Wnt signaling pathway involved in dorsal/ventral axis specification)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1903224"(regulation of endodermal cell differentiation)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-6809371|reactome:R-CEL-8980692|reactome:R-CEL-9013406|reactome:R-CEL-9013407|go:"GO:1904787"(positive regulation of asymmetric protein localization involved in cell fate determination)|refseq:NP_498236.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|mint:Q10953|interpro:IPR013284(Beta-catenin)|wormbase:B0336.1a reactome:R-CEL-4641265|wormbase:W10C8.2|reactome:R-CEL-8853884|reactome:R-CEL-3769402|refseq:NP_491053.4|ensemblmetazoa:W10C8.2.1(transcript)|ensemblmetazoa:WBGene00004077(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061853"(regulation of neuroblast migration)|go:"GO:2000746"(regulation of defecation rhythm)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|interpro:IPR028782|interpro:IPR036910|rcsb pdb:3C2G|go:"GO:1990907"(beta-catenin-TCF complex)|dip:DIP-25683N|reactome:R-CEL-201722|reactome:R-CEL-4086398|reactome:R-CEL-8951430 - - - figure legend:Fig 3|comment:"Delta-NTPOP-1 (residues 56–487) gives only a weak positive reaction with WRM-1, and does not react with BAR-1, unlike the full length molecule."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/10 2014/10/16 rogid:cvujZ6Ubdj3XgPVHjjPH3aOV2lI6239 rogid:kzktFe2ZSDObXvcMQsdR9o90wGI6239 intact-crc:1BFC1228C0967F53|rigid:TIJMG0pBDOkvpxgvHkxKcppSCaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9U9Y8 uniprotkb:Q10953 intact:EBI-318513|uniprotkb:O62395|uniprotkb:Q69YW9|uniprotkb:Q8WQB7|uniprotkb:Q9U343|uniprotkb:Q9UA07|uniprotkb:Q9Y198|ensemblmetazoa:W06F12.1a.1 intact:EBI-2530558|uniprotkb:O16145|ensemblmetazoa:B0336.1a.1|ensemblmetazoa:B0336.1a.2 psi-mi:nlk_caeel(display_long)|uniprotkb:nlk(gene name synonym)|uniprotkb:W06F12.1(orf name)|uniprotkb:lit-1(gene name)|psi-mi:lit-1(display_short)|uniprotkb:Nemo-like kinase(gene name synonym)|uniprotkb:Loss of intestine protein 1(gene name synonym) psi-mi:wrm1_caeel(display_long)|uniprotkb:wrm-1(gene name)|psi-mi:wrm-1(display_short)|uniprotkb:Worm armadillo protein 1(gene name synonym)|uniprotkb:B0336.1(orf name) psi-mi:"MI:0018"(two hybrid) Natarajan et al. (2001) pubmed:11560894|imex:IM-16907|mint:MINT-5214547 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3831809|imex:IM-16907-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022805.1|refseq:NP_001022806.1|refseq:NP_001022807.1|refseq:NP_001022808.1|refseq:NP_001022809.1|wormbase:W06F12.1a|wormbase:W06F12.1b|wormbase:W06F12.1c|wormbase:W06F12.1d|wormbase:W06F12.1e|reactome:R-CEL-4086398|ensemblmetazoa:W06F12.1a.1(transcript)|ensemblmetazoa:WBGene00003048(gene)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:1902554"(serine/threonine protein kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-25624N ensemblmetazoa:B0336.1a.1(transcript)|ensemblmetazoa:B0336.1a.2(transcript)|ensemblmetazoa:WBGene00006943(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042661"(regulation of mesodermal cell fate specification)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044332"(Wnt signaling pathway involved in dorsal/ventral axis specification)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1903224"(regulation of endodermal cell differentiation)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-6809371|reactome:R-CEL-8980692|reactome:R-CEL-9013406|reactome:R-CEL-9013407|go:"GO:1904787"(positive regulation of asymmetric protein localization involved in cell fate determination)|refseq:NP_498236.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|mint:Q10953|interpro:IPR013284(Beta-catenin)|wormbase:B0336.1a - - - figure legend:Fig 3|comment:"Delta-NTPOP-1 (residues 56–487) gives only a weak positive reaction with WRM-1, and does not react with BAR-1, unlike the full length molecule."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/10 2014/10/16 rogid:A/PDBtOSh+boZbWJL/ky/9hv+jg6239 rogid:cvujZ6Ubdj3XgPVHjjPH3aOV2lI6239 intact-crc:410BD98888DDBAA5|rigid:e2Lns2XCUbS15T/h1b+zpawn4sg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18825 uniprotkb:Q10666 intact:EBI-2528850|ensemblmetazoa:C54D1.6.1 intact:EBI-317870|uniprotkb:O45007|ensemblmetazoa:W10C8.2.1 psi-mi:bar1_caeel(display_long)|uniprotkb:bar-1(gene name)|psi-mi:bar-1(display_short)|uniprotkb:pvl-1(gene name synonym)|uniprotkb:spy-1(gene name synonym)|uniprotkb:Protruding vulva protein 1(gene name synonym)|uniprotkb:Suppressor of polyray 1(gene name synonym)|uniprotkb:C54D1.6(orf name) psi-mi:pop1_caeel(display_long)|uniprotkb:pop-1(gene name)|psi-mi:pop-1(display_short)|uniprotkb:W10C8.2(orf name)|uniprotkb:Posterior pharynx defect protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Natarajan et al. (2001) pubmed:11560894|imex:IM-16907|mint:MINT-5214547 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3679536|imex:IM-16907-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509206.1|wormbase:C54D1.6|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|ensemblmetazoa:C54D1.6.1(transcript)|ensemblmetazoa:WBGene00000238(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007617"(mating behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018991"(oviposition)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040024"(dauer larval development)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:0040035"(hermaphrodite genitalia development)|reactome:R-CEL-6798695|reactome:R-CEL-5218920|reactome:R-CEL-6809371|reactome:R-CEL-8980692|reactome:R-CEL-9013406|reactome:R-CEL-9013407 reactome:R-CEL-4641265|wormbase:W10C8.2|reactome:R-CEL-8853884|reactome:R-CEL-3769402|refseq:NP_491053.4|ensemblmetazoa:W10C8.2.1(transcript)|ensemblmetazoa:WBGene00004077(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061853"(regulation of neuroblast migration)|go:"GO:2000746"(regulation of defecation rhythm)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|interpro:IPR028782|interpro:IPR036910|rcsb pdb:3C2G|go:"GO:1990907"(beta-catenin-TCF complex)|dip:DIP-25683N|reactome:R-CEL-201722|reactome:R-CEL-4086398|reactome:R-CEL-8951430 - - - figure legend:Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/10 2014/10/16 rogid:2cYTDh2x+j/Ln7GTP5KQQ3eZO3A6239 rogid:kzktFe2ZSDObXvcMQsdR9o90wGI6239 intact-crc:4DC00297D560674A|rigid:qxiXEV1sPq1GOBf7B5KtNT3PMZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q21227 uniprotkb:Q18825 intact:EBI-2413521|uniprotkb:O62302|ensemblmetazoa:K04G2.8b.1 intact:EBI-2528850|ensemblmetazoa:C54D1.6.1 psi-mi:apr1_caeel(display_long)|uniprotkb:apr-1(gene name)|psi-mi:apr-1(display_short)|uniprotkb:K04G2.8(orf name) psi-mi:bar1_caeel(display_long)|uniprotkb:bar-1(gene name)|psi-mi:bar-1(display_short)|uniprotkb:pvl-1(gene name synonym)|uniprotkb:spy-1(gene name synonym)|uniprotkb:Protruding vulva protein 1(gene name synonym)|uniprotkb:Suppressor of polyray 1(gene name synonym)|uniprotkb:C54D1.6(orf name) psi-mi:"MI:0018"(two hybrid) Natarajan et al. (2001) pubmed:11560894|imex:IM-16907|mint:MINT-5214547 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3831806|imex:IM-16907-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021547.1|refseq:NP_492217.2|wormbase:K04G2.8a|wormbase:K04G2.8b|reactome:R-CEL-195253|reactome:R-CEL-3769402|dip:DIP-41257N|reactome:R-CEL-196299|reactome:R-CEL-111465|ensemblmetazoa:K04G2.8b.1(transcript)|ensemblmetazoa:WBGene00000156(gene)|go:"GO:0000003"(reproduction)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0016342"(catenin complex)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0040025"(vulval development)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818 refseq:NP_509206.1|wormbase:C54D1.6|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|ensemblmetazoa:C54D1.6.1(transcript)|ensemblmetazoa:WBGene00000238(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007617"(mating behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018991"(oviposition)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040024"(dauer larval development)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:0040035"(hermaphrodite genitalia development)|reactome:R-CEL-6798695|reactome:R-CEL-5218920|reactome:R-CEL-6809371|reactome:R-CEL-8980692|reactome:R-CEL-9013406|reactome:R-CEL-9013407 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/10 2014/10/16 rogid:3MPRfH/P3BFnIp1q673XvP3KSM06239 rogid:2cYTDh2x+j/Ln7GTP5KQQ3eZO3A6239 intact-crc:CE28EE542BF0CA41|rigid:M3Ye2MBiUb1LVLUXLUK0GVY1t3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q21227 uniprotkb:O44326 intact:EBI-2413521|uniprotkb:O62302|ensemblmetazoa:K04G2.8b.1 intact:EBI-317320|ensemblmetazoa:K05C4.6a.1|ensemblmetazoa:K05C4.6a.2 psi-mi:apr1_caeel(display_long)|uniprotkb:apr-1(gene name)|psi-mi:apr-1(display_short)|uniprotkb:K04G2.8(orf name) psi-mi:hmp2_caeel(display_long)|uniprotkb:hmp-2(gene name)|psi-mi:hmp-2(display_short)|uniprotkb:Protein humpback-2(gene name synonym)|uniprotkb:K05C4.6(orf name) psi-mi:"MI:0018"(two hybrid) Natarajan et al. (2001) pubmed:11560894|imex:IM-16907|mint:MINT-5214547 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3831803|imex:IM-16907-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021547.1|refseq:NP_492217.2|wormbase:K04G2.8a|wormbase:K04G2.8b|reactome:R-CEL-195253|reactome:R-CEL-3769402|dip:DIP-41257N|reactome:R-CEL-196299|reactome:R-CEL-111465|ensemblmetazoa:K04G2.8b.1(transcript)|ensemblmetazoa:WBGene00000156(gene)|go:"GO:0000003"(reproduction)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0016342"(catenin complex)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0040025"(vulval development)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818 wormbase:K05C4.6a|reactome:R-CEL-8853884|refseq:NP_001252426.1|rcsb pdb:4R0Z|rcsb pdb:4R10|rcsb pdb:4R11|rcsb pdb:5XA5|interpro:IPR016024(Armadillo-type fold)|ensemblmetazoa:K05C4.6a.1(transcript)|ensemblmetazoa:K05C4.6a.2(transcript)|ensemblmetazoa:WBGene00001979(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|reactome:R-CEL-6798695|reactome:R-CEL-351906|reactome:R-CEL-525793|reactome:R-CEL-8980692|reactome:R-CEL-9013406|reactome:R-CEL-9013407|dip:DIP-27261N|reactome:R-CEL-195253|reactome:R-CEL-196299|reactome:R-CEL-201681|reactome:R-CEL-201722|reactome:R-CEL-3134973|reactome:R-CEL-3769402|reactome:R-CEL-4086398|reactome:R-CEL-5218920|reactome:R-CEL-6809371|reactome:R-CEL-8951430 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/10 2014/10/16 rogid:3MPRfH/P3BFnIp1q673XvP3KSM06239 rogid:8DLyhATsxCZq1Vthd5haUE54Kmw6239 intact-crc:1DBECE00BBDEC2DC|rigid:9szEhlsq7Z6WlDVRBnIQJexMpfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)