#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20433 uniprotkb:P38249 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 intact:EBI-8981|ensemblfungi:YBR079C|uniprotkb:D6VQ78 psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:eif3a_yeast(display_long)|uniprotkb:RPG1(gene name)|psi-mi:RPG1(display_short)|uniprotkb:TIF32(gene name synonym)|uniprotkb:YBR079C(locus name)|uniprotkb:YBR0734(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 110 kDa subunit homolog(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p110 subunit homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945603|imex:IM-15176-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 ensemblfungi:YBR079C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|rcsb pdb:3JAP|rcsb pdb:4K51|rcsb pdb:4U1C|rcsb pdb:4U1D|rcsb pdb:4U1E|ensemblfungi:YBR079C(gene)|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|rcsb pdb:6FYX|refseq:NP_009635.1|sgd:S000000283|mint:P38249|dip:DIP-5870N psi-mi:"MI:0469"(intact) crc64:72A8A26871B87775 crc64:93EFFA6B2FC8286D comment:Additional Rbp proteins were identified by silver stain only.|figure legend:Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 rogid:XF9unC2aloHrBY2QTVLwlMbcJhY559292 intact-crc:06A680D21E786D32|rigid:2L8OD6vpe+QFzz3VmaNeVh5Mcbw false calmodulin binding peptide plus protein a tag:?-? identified peptide:171-184|identified peptide:42-54|identified peptide:78-103|identified peptide:220-235|identified peptide:365-379|identified peptide:494-505|identified peptide:680-690|identified peptide:777-787 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20433 uniprotkb:P32497 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945603|imex:IM-15176-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N psi-mi:"MI:0469"(intact) crc64:72A8A26871B87775 crc64:EE05097C44C45A4C comment:Additional Rbp proteins were identified by silver stain only.|figure legend:Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 intact-crc:06A680D21E786D32|rigid:2L8OD6vpe+QFzz3VmaNeVh5Mcbw false calmodulin binding peptide plus protein a tag:?-? identified peptide:119-129|identified peptide:170-187 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P20433 uniprotkb:P53617 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2 psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945603|imex:IM-15176-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N psi-mi:"MI:0469"(intact) crc64:72A8A26871B87775 crc64:75082BDB0C42AE37 comment:Additional Rbp proteins were identified by silver stain only.|figure legend:Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292 intact-crc:06A680D21E786D32|rigid:2L8OD6vpe+QFzz3VmaNeVh5Mcbw false calmodulin binding peptide plus protein a tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P32497 uniprotkb:P20433 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945648|imex:IM-15176-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 psi-mi:"MI:0469"(intact) crc64:EE05097C44C45A4C crc64:72A8A26871B87775 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 intact-crc:F6F2947F29137084|rigid:FrgVY8AaUQr40IFhI7FQ7JnVWsE false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32497 uniprotkb:P04147 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 intact:EBI-12823|ensemblfungi:YER165W|uniprotkb:D3DM73 psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:pabp_yeast(display_long)|uniprotkb:PAB1(gene name)|psi-mi:PAB1(display_short)|uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym)|uniprotkb:Polyadenylate tail-binding protein(gene name synonym)|uniprotkb:YER165W(locus name) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945648|imex:IM-15176-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N ensemblfungi:YER165W(gene)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008143"("poly(A) binding")|ensemblfungi:YER165W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|rcsb pdb:1IFW|rcsb pdb:6R5K|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-156827|refseq:NP_011092.1|sgd:S000000967|mint:P04147|dip:DIP-2275N psi-mi:"MI:0469"(intact) crc64:EE05097C44C45A4C crc64:4F97E494753E17C7 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 rogid:6ZjESO1CUgykLdGVlTuZoFRwqyg559292 intact-crc:F6F2947F29137084|rigid:FrgVY8AaUQr40IFhI7FQ7JnVWsE false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32497 uniprotkb:P20433 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945656|imex:IM-15176-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 psi-mi:"MI:0469"(intact) crc64:EE05097C44C45A4C crc64:72A8A26871B87775 figure legend:Fig. 1A|comment:Samples treated with a cocktail of RNase A and RNase T1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 intact-crc:4989600A638CB49E|rigid:eLb6yaoKB2letP4gnPLWHeCzE8A false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q05775 uniprotkb:P34087 intact:EBI-8944|ensemblfungi:YLR192C|uniprotkb:D6VYJ5 intact:EBI-15790|uniprotkb:D6VT36|ensemblfungi:YDR404C psi-mi:eif3j_yeast(display_long)|uniprotkb:HCR1(gene name)|psi-mi:HCR1(display_short)|uniprotkb:YLR192C(locus name)|uniprotkb:L8167.11(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 30 kDa subunit(gene name synonym) psi-mi:rpb7_yeast(display_long)|uniprotkb:RPB7(gene name)|psi-mi:RPB7(display_short)|uniprotkb:YDR404C(locus name)|uniprotkb:D9509.22(orf name)|uniprotkb:B16(gene name synonym) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945671|imex:IM-15176-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR192C(gene)|ensemblfungi:YLR192C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|rcsb pdb:6ZCE|rcsb pdb:7A1G|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_013293.1|sgd:S000004182|mint:Q05775|dip:DIP-4532N sgd:S000002812|refseq:NP_010692.3|dip:DIP-725N|mint:P34087|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2B8K|ensemblfungi:YDR404C(gene)|ensemblfungi:YDR404C_mRNA(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63 psi-mi:"MI:0469"(intact) crc64:BDDBC5943DD7F9BB crc64:44C85603A93CDE67 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/11/23 2014/10/16 rogid:thTWfBFTNIvPGqVVPhrkhxb6MuU559292 rogid:Q+VUnkG9LhmQRZNmkFSdmcNozjE559292 intact-crc:4099F2EED5F67D0A|rigid:lMX5m0jPOy58y5ir98Dt9WQXnMM false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q05775 uniprotkb:P20433 intact:EBI-8944|ensemblfungi:YLR192C|uniprotkb:D6VYJ5 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 psi-mi:eif3j_yeast(display_long)|uniprotkb:HCR1(gene name)|psi-mi:HCR1(display_short)|uniprotkb:YLR192C(locus name)|uniprotkb:L8167.11(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 30 kDa subunit(gene name synonym) psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945671|imex:IM-15176-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR192C(gene)|ensemblfungi:YLR192C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|rcsb pdb:6ZCE|rcsb pdb:7A1G|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_013293.1|sgd:S000004182|mint:Q05775|dip:DIP-4532N go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 psi-mi:"MI:0469"(intact) crc64:BDDBC5943DD7F9BB crc64:72A8A26871B87775 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/11/23 2014/10/16 rogid:thTWfBFTNIvPGqVVPhrkhxb6MuU559292 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 intact-crc:4099F2EED5F67D0A|rigid:lMX5m0jPOy58y5ir98Dt9WQXnMM false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32497 uniprotkb:P34087 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 intact:EBI-15790|uniprotkb:D6VT36|ensemblfungi:YDR404C psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:rpb7_yeast(display_long)|uniprotkb:RPB7(gene name)|psi-mi:RPB7(display_short)|uniprotkb:YDR404C(locus name)|uniprotkb:D9509.22(orf name)|uniprotkb:B16(gene name synonym) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945682|imex:IM-15176-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N sgd:S000002812|refseq:NP_010692.3|dip:DIP-725N|mint:P34087|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2B8K|ensemblfungi:YDR404C(gene)|ensemblfungi:YDR404C_mRNA(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63 psi-mi:"MI:0469"(intact) crc64:EE05097C44C45A4C crc64:44C85603A93CDE67 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/11/23 2014/10/16 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 rogid:Q+VUnkG9LhmQRZNmkFSdmcNozjE559292 intact-crc:0DF870356AD18229|rigid:33In3gDD1HvPosKfAb2xw2lnsog false necessary binding region:1-157 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32497 uniprotkb:P20433 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:"MI:0096"(pull down) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945682|imex:IM-15176-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 psi-mi:"MI:0469"(intact) crc64:EE05097C44C45A4C crc64:72A8A26871B87775 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/11/23 2014/10/16 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 intact-crc:0DF870356AD18229|rigid:33In3gDD1HvPosKfAb2xw2lnsog false necessary binding region:1-157 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P34087 uniprotkb:P20433 intact:EBI-15790|uniprotkb:D6VT36|ensemblfungi:YDR404C intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 psi-mi:rpb7_yeast(display_long)|uniprotkb:RPB7(gene name)|psi-mi:RPB7(display_short)|uniprotkb:YDR404C(locus name)|uniprotkb:D9509.22(orf name)|uniprotkb:B16(gene name synonym) psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:"MI:0018"(two hybrid) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945695|imex:IM-15176-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002812|refseq:NP_010692.3|dip:DIP-725N|mint:P34087|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2B8K|ensemblfungi:YDR404C(gene)|ensemblfungi:YDR404C_mRNA(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63 go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 psi-mi:"MI:0469"(intact) crc64:44C85603A93CDE67 crc64:72A8A26871B87775 figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:Q+VUnkG9LhmQRZNmkFSdmcNozjE559292 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 intact-crc:AB4B560F00CC4202|rigid:h8klCPbdzNzlxCPPMt6YKFlEIc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20433 uniprotkb:P32497 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6 psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945699|imex:IM-15176-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N psi-mi:"MI:0469"(intact) crc64:72A8A26871B87775 crc64:EE05097C44C45A4C figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292 intact-crc:5026B180D8515E8C|rigid:eLb6yaoKB2letP4gnPLWHeCzE8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05775 uniprotkb:P20433 intact:EBI-8944|ensemblfungi:YLR192C|uniprotkb:D6VYJ5 intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44 psi-mi:eif3j_yeast(display_long)|uniprotkb:HCR1(gene name)|psi-mi:HCR1(display_short)|uniprotkb:YLR192C(locus name)|uniprotkb:L8167.11(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 30 kDa subunit(gene name synonym) psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym) psi-mi:"MI:0018"(two hybrid) Harel-Sharvit et al. (2010) pubmed:21074047|imex:IM-15176 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2945703|imex:IM-15176-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR192C(gene)|ensemblfungi:YLR192C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|rcsb pdb:6ZCE|rcsb pdb:7A1G|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_013293.1|sgd:S000004182|mint:Q05775|dip:DIP-4532N go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433 psi-mi:"MI:0469"(intact) crc64:BDDBC5943DD7F9BB crc64:72A8A26871B87775 figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/11/23 2014/10/16 rogid:thTWfBFTNIvPGqVVPhrkhxb6MuU559292 rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292 intact-crc:E92F961320C77C44|rigid:IubLBcs37NCcGm36rTK5YWR4l6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)