#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54132	uniprotkb:Q13472	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166227|mint:MINT-8048961|imex:IM-15138-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8048965(identity)	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8048967(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	intact-crc:A8619943E6089AF5|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q9H9A7	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166227|mint:MINT-8048961|imex:IM-15138-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8048965(identity)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8048963(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	intact-crc:A8619943E6089AF5|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q5UIP0	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166227|mint:MINT-8048961|imex:IM-15138-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8048965(identity)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8048964(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	intact-crc:A8619943E6089AF5|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q96E14	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-2555534|uniprotkb:B3KVZ6|uniprotkb:Q49AE2|uniprotkb:Q8TBL0|ensembl:ENSP00000310356	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rmi2_human(display_long)|uniprotkb:C16orf75(gene name synonym)|uniprotkb:BLM-associated protein of 18 kDa(gene name synonym)|uniprotkb:RMI2(gene name)|psi-mi:RMI2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166227|mint:MINT-8048961|imex:IM-15138-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8048965(identity)	refseq:NP_689521.1|ensembl:ENSG00000175643(gene)|ensembl:ENST00000312499(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0033045"(regulation of sister chromatid segregation)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR032245|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|dip:DIP-56480N|mint:MINT-8048966(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:C+BkMgfVWJYrYzHyitGVU1nwnQg9606	intact-crc:A8619943E6089AF5|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9A7	uniprotkb:Q13472	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166275|mint:MINT-8048980|imex:IM-15138-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8048982(identity)	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8048990(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	intact-crc:24FC774D927A5BC1|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9A7	uniprotkb:P54132	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166275|mint:MINT-8048980|imex:IM-15138-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8048982(identity)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8048986(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	intact-crc:24FC774D927A5BC1|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9A7	uniprotkb:Q96E14	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	intact:EBI-2555534|uniprotkb:B3KVZ6|uniprotkb:Q49AE2|uniprotkb:Q8TBL0|ensembl:ENSP00000310356	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:rmi2_human(display_long)|uniprotkb:C16orf75(gene name synonym)|uniprotkb:BLM-associated protein of 18 kDa(gene name synonym)|uniprotkb:RMI2(gene name)|psi-mi:RMI2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166275|mint:MINT-8048980|imex:IM-15138-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8048982(identity)	refseq:NP_689521.1|ensembl:ENSG00000175643(gene)|ensembl:ENST00000312499(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0033045"(regulation of sister chromatid segregation)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR032245|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|dip:DIP-56480N|mint:MINT-8048988(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	rogid:C+BkMgfVWJYrYzHyitGVU1nwnQg9606	intact-crc:24FC774D927A5BC1|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9A7	uniprotkb:Q5UIP0	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166275|mint:MINT-8048980|imex:IM-15138-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8048982(identity)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8048984(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	intact-crc:24FC774D927A5BC1|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:Q9H9A7	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8049012(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:P27694	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N|mint:MINT-8049029(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:Q13472	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8049020(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:P15927	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N|mint:MINT-8049032(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:P35244	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N|mint:MINT-8049033(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:P54132	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049016(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:Q96E14	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-2555534|uniprotkb:B3KVZ6|uniprotkb:Q49AE2|uniprotkb:Q8TBL0|ensembl:ENSP00000310356	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rmi2_human(display_long)|uniprotkb:C16orf75(gene name synonym)|uniprotkb:BLM-associated protein of 18 kDa(gene name synonym)|uniprotkb:RMI2(gene name)|psi-mi:RMI2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166317|mint:MINT-8049010|imex:IM-15138-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049014(identity)	refseq:NP_689521.1|ensembl:ENSG00000175643(gene)|ensembl:ENST00000312499(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0033045"(regulation of sister chromatid segregation)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR032245|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|dip:DIP-56480N|mint:MINT-8049018(identity)	-	-	-	figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2015/01/09	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:C+BkMgfVWJYrYzHyitGVU1nwnQg9606	intact-crc:9B495440475CBEF8|rigid:6IayJdMRzj1bl4ydQXHON95KVDM	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5UIP0	uniprotkb:Q9H9A7	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166296|mint:MINT-8048995|imex:IM-15138-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8048999(identity)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8048997(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	intact-crc:C3478BAE8D20DEF7|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:P54132	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166296|mint:MINT-8048995|imex:IM-15138-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8048999(identity)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049001(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	intact-crc:C3478BAE8D20DEF7|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:Q13472	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166296|mint:MINT-8048995|imex:IM-15138-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8048999(identity)	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8049005(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	intact-crc:C3478BAE8D20DEF7|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:Q96E14	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-2555534|uniprotkb:B3KVZ6|uniprotkb:Q49AE2|uniprotkb:Q8TBL0|ensembl:ENSP00000310356	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rmi2_human(display_long)|uniprotkb:C16orf75(gene name synonym)|uniprotkb:BLM-associated protein of 18 kDa(gene name synonym)|uniprotkb:RMI2(gene name)|psi-mi:RMI2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166296|mint:MINT-8048995|imex:IM-15138-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8048999(identity)	refseq:NP_689521.1|ensembl:ENSG00000175643(gene)|ensembl:ENST00000312499(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0033045"(regulation of sister chromatid segregation)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR032245|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|dip:DIP-56480N|mint:MINT-8049003(identity)	-	-	-	figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:C+BkMgfVWJYrYzHyitGVU1nwnQg9606	intact-crc:C3478BAE8D20DEF7|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:Q5UIP0	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166374|mint:MINT-8049120|imex:IM-15138-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049123(identity)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049125(identity)	-	-	-	figure legend:sf2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	intact-crc:4E30543949620330|rigid:Fmi+eKqEAkWHeLdTngNNre152PU	false	flag tag:?-?(MINT-8049143)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q5UIP0	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166399|mint:MINT-8049038|imex:IM-15138-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049044(identity)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049042(identity)	go:"GO:0005634"(nucleus)	-	-	figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	intact-crc:D93AF92B5F859300|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q9H9A7	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166399|mint:MINT-8049038|imex:IM-15138-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049044(identity)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8049040(identity)	go:"GO:0005634"(nucleus)	-	-	figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	intact-crc:D93AF92B5F859300|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q96E14	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-2555534|uniprotkb:B3KVZ6|uniprotkb:Q49AE2|uniprotkb:Q8TBL0|ensembl:ENSP00000310356	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rmi2_human(display_long)|uniprotkb:C16orf75(gene name synonym)|uniprotkb:BLM-associated protein of 18 kDa(gene name synonym)|uniprotkb:RMI2(gene name)|psi-mi:RMI2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166399|mint:MINT-8049038|imex:IM-15138-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049044(identity)	refseq:NP_689521.1|ensembl:ENSG00000175643(gene)|ensembl:ENST00000312499(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0033045"(regulation of sister chromatid segregation)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR032245|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|dip:DIP-56480N|mint:MINT-8049046(identity)	go:"GO:0005634"(nucleus)	-	-	figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:C+BkMgfVWJYrYzHyitGVU1nwnQg9606	intact-crc:D93AF92B5F859300|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q13472	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166399|mint:MINT-8049038|imex:IM-15138-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049044(identity)	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8049048(identity)	go:"GO:0005634"(nucleus)	-	-	figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	intact-crc:D93AF92B5F859300|rigid:BTOYS5oFJkgd18iMmf0rWSPwjQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54132	uniprotkb:Q5UIP0	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166457|mint:MINT-8049107|imex:IM-15138-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049112(identity)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049110(identity)	go:"GO:0005634"(nucleus)	-	-	figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2010/10/20	2014/10/16	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	intact-crc:1BA2D80C7F8F9220|rigid:3kaqcv4L7FlrBH31Cjotj3KZoN0	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q5UIP0	uniprotkb:P54132	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621372|ensembl:ENSP00000347232|ensembl:ENSP00000506117|uniprotkb:Q52M96	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:blm_human(display_long)|uniprotkb:RecQ protein-like 3(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 2(gene name synonym)|uniprotkb:BLM(gene name)|psi-mi:BLM(display_short)|uniprotkb:RECQ2(gene name synonym)|uniprotkb:RECQL3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166534|mint:MINT-8049128|imex:IM-15138-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049132(identity)	go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|ensembl:ENST00000355112(transcript)|go:"GO:0003697"(single-stranded DNA binding)|ensembl:ENST00000680772(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0004386"(helicase activity)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010165"(response to X-ray)|go:"GO:0016363"(nuclear matrix)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0016605"(PML body)|go:"GO:0031297"(replication fork processing)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000800"(lateral element)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061749"(forked DNA-dependent helicase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0090329"(regulation of DNA-dependent DNA replication)|go:"GO:0090656"(t-circle formation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|go:"GO:0048478"(replication fork protection)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012532(BDHCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR032284|interpro:IPR032437|interpro:IPR032439|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR036388|mint:P54132|rcsb pdb:2KV2|rcsb pdb:2MH9|rcsb pdb:2RRD|rcsb pdb:3WE2|rcsb pdb:3WE3|rcsb pdb:4CDG|rcsb pdb:4CGZ|rcsb pdb:4O3M|rcsb pdb:5LUP|rcsb pdb:5MK5|rcsb pdb:5U6K|rcsb pdb:7AUC|rcsb pdb:7AUD|reactome:R-HSA-174414|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR036390|ensembl:ENSG00000197299(gene)|refseq:NP_000048.1|refseq:NP_001274175.1|refseq:NP_001274176.1|refseq:NP_001274177.1|dip:DIP-33322N|mint:MINT-8049134(identity)	-	-	-	comment:homomint|figure legend:f5e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:FQ+HJ2RwfvP7EwtDzFX7ESe/qEA9606	intact-crc:B62D03ABFB81551C|rigid:C9fD+BQ0eccDjwEfAMLcIGUK2tE	false	flag tag:?-?(MINT-8049150)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:Q13472	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166534|mint:MINT-8049128|imex:IM-15138-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049132(identity)	refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8049138(identity)	-	-	-	comment:homomint|figure legend:f5e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606	intact-crc:B62D03ABFB81551C|rigid:C9fD+BQ0eccDjwEfAMLcIGUK2tE	false	flag tag:?-?(MINT-8049150)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5UIP0	uniprotkb:Q9H9A7	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Xu et al. (2010)	pubmed:20711169|imex:IM-15138|mint:MINT-8048867|doi:10.1038/emboj.2010.186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8166534|mint:MINT-8049128|imex:IM-15138-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-8049132(identity)	ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N|mint:MINT-8049130(identity)	-	-	-	comment:homomint|figure legend:f5e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2010/10/20	2014/10/16	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606	intact-crc:B62D03ABFB81551C|rigid:C9fD+BQ0eccDjwEfAMLcIGUK2tE	false	flag tag:?-?(MINT-8049150)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)