#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q921E6 uniprotkb:P11499 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:379-392|identified peptide:292-306|identified peptide:83-95 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q99L45 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2527165|uniprotkb:Q9CSH6|uniprotkb:Q9CT12|ensembl:ENSMUSP00000096777|ensembl:ENSMUSP00000128257 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:if2b_mouse(display_long)|uniprotkb:Eif2s2(gene name)|psi-mi:Eif2s2(display_short)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_080306.1|ensembl:ENSMUSG00000074656(gene)|ensembl:ENSMUST00000099173(transcript)|ensembl:ENSMUST00000166171(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0008584"(male gonad development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:Q99L45|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:rFKfeTTSJtJOwP6jsL1OCSQKsCU10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:65-79 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q99JI4 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-992120|uniprotkb:Q9CWZ1|ensembl:ENSMUSP00000022256 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:psmd6_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Psmd6(gene name)|psi-mi:Psmd6(display_short)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_079826.2|ensembl:ENSMUSG00000021737(gene)|ensembl:ENSMUST00000022256(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-983168 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:7n3IJIpvsL7lkD/Io01YJOINOYk10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:2-13|identified peptide:147-159 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:C0HKE1 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2527113|uniprotkb:P22752|uniprotkb:P10812|uniprotkb:Q149U0|uniprotkb:Q5SZZ2|ensembl:ENSMUSP00000077477|ensembl:ENSMUSP00000080088|ensembl:ENSMUSP00000088281|ensembl:ENSMUSP00000088285|ensembl:ENSMUSP00000089335|ensembl:ENSMUSP00000089339|ensembl:ENSMUSP00000089345|ensembl:ENSMUSP00000100034|ensembl:ENSMUSP00000127684 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:h2a1b_mouse(display_long)|uniprotkb:H2ac4(gene name)|psi-mi:H2ac4(display_short)|uniprotkb:Hist1h2ab(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 ensembl:ENSMUSG00000061615(gene)|ensembl:ENSMUSG00000069270(gene)|ensembl:ENSMUSG00000069272(gene)|ensembl:ENSMUSG00000069301(gene)|ensembl:ENSMUSG00000069309(gene)|ensembl:ENSMUSG00000071478(gene)|ensembl:ENSMUSG00000071516(gene)|ensembl:ENSMUSG00000094248(gene)|ensembl:ENSMUSG00000094777(gene)|ensembl:ENSMUST00000070124(transcript)|ensembl:ENSMUST00000078369(transcript)|ensembl:ENSMUST00000081342(transcript)|ensembl:ENSMUST00000090776(transcript)|ensembl:ENSMUST00000091741(transcript)|ensembl:ENSMUST00000091751(transcript)|ensembl:ENSMUST00000102969(transcript)|ensembl:ENSMUST00000171127(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:C0HKE1|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|ensembl:ENSMUST00000091745(transcript)|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5689901|reactome:R-MMU-606279|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|reactome:R-MMU-212300|refseq:NP_001171015.1|refseq:NP_783591.2|refseq:NP_835489.1|refseq:NP_835491.1|refseq:NP_835492.1|refseq:NP_835493.1|refseq:NP_835494.1|refseq:NP_835495.1|refseq:NP_835496.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:4Qno1mMYZB6FdNoojrzulWLVq8410090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:22-30|identified peptide:101-119|identified peptide:44-72 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P97351 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-773982|ensembl:ENSMUSP00000029722 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rs3a_mouse(display_long)|uniprotkb:Rps3a(gene name)|psi-mi:Rps3a(display_short)|uniprotkb:Protein TU-11(gene name synonym)|uniprotkb:Rps3a1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_058655.3|ensembl:ENSMUSG00000028081(gene)|ensembl:ENSMUST00000029722(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:pi623FvaPjjNAiN44zPHjtep4gs10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:66-82 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P62900 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2527089|uniprotkb:P12947|ensembl:ENSMUSP00000083722|ensembl:ENSMUSP00000136354|ensembl:ENSMUSP00000137631 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rl31_mouse(display_long)|uniprotkb:Rpl31(gene name)|psi-mi:Rpl31(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 ensembl:ENSMUSG00000073702(gene)|ensembl:ENSMUST00000086535(transcript)|ensembl:ENSMUST00000178079(transcript)|ensembl:ENSMUST00000179954(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62900|rcsb pdb:6SWA|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-156827|refseq:NP_444487.1|refseq:NP_001239147.1|refseq:NP_001239148.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:77LFR7/2somk6blVogZf1XFdJLk10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:102-115 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P07901 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:88-100|identified peptide:388-401|identified peptide:210-224|identified peptide:301-315 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q91VJ4 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:25-41|identified peptide:403-434 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q8CIG8 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2527009|uniprotkb:Q3TNN1|uniprotkb:Q9QZS9 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:anm5_mouse(display_long)|uniprotkb:Prmt5(gene name)|psi-mi:Prmt5(display_short)|uniprotkb:Jbp1(gene name synonym)|uniprotkb:Skb1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 interpro:IPR035075|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|reactome:R-MMU-191859|reactome:R-MMU-3214858|reactome:R-MMU-6804760|refseq:NP_038796.2|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR029063|refseq:NP_001300835.1|refseq:NP_001300836.1|interpro:IPR025799|interpro:IPR035247|interpro:IPR035248|mint:Q8CIG8 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:xMQdLXo5TNQQFK9XjxjH+5/ZwNA10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:77-85|identified peptide:228-240|identified peptide:202-220 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q8VDM4 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-991994|ensembl:ENSMUSP00000007212 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:psmd2_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Psmd2(gene name)|psi-mi:Psmd2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_598862.1|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|mint:Q8VDM4|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|ensembl:ENSMUSG00000006998(gene)|ensembl:ENSMUST00000007212(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-202424|reactome:R-MMU-68827|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-68949 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:ws66cEUC+w+9QrTLWuEBVQZwsDQ10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:370-389|identified peptide:880-901 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q99LC4 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526893 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:q99lc4_mouse(display_long)|uniprotkb:Igh(gene name)|psi-mi:Igh(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 rcsb pdb:2NTF|rcsb pdb:2VIR|rcsb pdb:2VIS|rcsb pdb:1E6J|rcsb pdb:1JHK|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013106(Immunoglobulin V-set)|rcsb pdb:1F58|rcsb pdb:1JNL|rcsb pdb:1JNN|rcsb pdb:2A1W|rcsb pdb:2VIT|rcsb pdb:4Q0X|rcsb pdb:1AE6|rcsb pdb:1GIG|interpro:IPR036179|rcsb pdb:6C5H|rcsb pdb:6C5I|rcsb pdb:6C5J|rcsb pdb:6C5K psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:rb3tORVJa5CtHaOyY25mnAHnXQc10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:339-350|identified peptide:409-430|identified peptide:265-274 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P14869 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-529949|uniprotkb:Q99L54|ensembl:ENSMUSP00000083705 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rla0_mouse(display_long)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Rplp0(gene name)|psi-mi:Rplp0(display_short)|uniprotkb:Arbp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_031501.1|ensembl:ENSMUSG00000067274(gene)|ensembl:ENSMUST00000086519(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042277"(peptide binding)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P14869|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:WHl41TZwjtqRSeIExT3vyjrZsJs10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:67-77|identified peptide:135-146|identified peptide:267-297 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P62192 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-357610|uniprotkb:P49014|uniprotkb:Q96AZ3|uniprotkb:Q03527|ensembl:ENSMUSP00000021595 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:prs4_mouse(display_long)|uniprotkb:Psmc1(gene name)|psi-mi:Psmc1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000021178(gene)|ensembl:ENSMUST00000021595(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62192|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|refseq:NP_032973.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:372-387|identified peptide:179-198 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q9CZM2 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526843|uniprotkb:Q9CWI5|ensembl:ENSMUSP00000078388|ensembl:ENSMUSP00000079163|ensembl:ENSMUSP00000098362|ensembl:ENSMUSP00000108217 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rl15_mouse(display_long)|uniprotkb:Rpl15(gene name)|psi-mi:Rpl15(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_079862.1|ensembl:ENSMUSG00000012405(gene)|ensembl:ENSMUST00000079419(transcript)|ensembl:ENSMUST00000080281(transcript)|ensembl:ENSMUST00000100799(transcript)|ensembl:ENSMUST00000112598(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:Q9CZM2|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:XP_006518143.1|refseq:XP_006518144.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:129-140|identified peptide:115-128 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q3UZ39 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2270972|uniprotkb:O70323|uniprotkb:Q3TS94|ensembl:ENSMUSP00000095254 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:lrrf1_mouse(display_long)|uniprotkb:H186 FLAP(gene name synonym)|uniprotkb:FLI-LRR-associated protein 1(gene name synonym)|uniprotkb:Lrrfip1(gene name)|psi-mi:Lrrfip1(display_short)|uniprotkb:Flap(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001104781.1|refseq:NP_001104782.1|refseq:NP_032541.1|ensembl:ENSMUSG00000026305(gene)|ensembl:ENSMUST00000097649(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR019139|mint:Q3UZ39 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:LL6ZrfCorNlWgE0W5E5+LVfsqWo10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:67-85|identified peptide:402-432|identified peptide:130-140 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P84099 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526813|uniprotkb:P14118|uniprotkb:P22908|ensembl:ENSMUSP00000017548 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rl19_mouse(display_long)|uniprotkb:Rpl19(gene name)|psi-mi:Rpl19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_033104.2|ensembl:ENSMUSG00000017404(gene)|ensembl:ENSMUST00000017548(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84099|rcsb pdb:1K8D|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:22-38 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q61188 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:223-234|identified peptide:223-241|identified peptide:613-629|identified peptide:420-441 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P62843 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526764|uniprotkb:P11174|uniprotkb:Q52KC9|ensembl:ENSMUSP00000069004 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rs15_mouse(display_long)|uniprotkb:Rps15(gene name)|psi-mi:Rps15(display_short)|uniprotkb:Rig(gene name synonym)|uniprotkb:RIG protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 ensembl:ENSMUSG00000063457(gene)|ensembl:ENSMUST00000068408(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|interpro:IPR023575|mint:P62843|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_033117.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:lJJOew1txuTwFlhKu4Z+AkPS5H010090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:82-100|identified peptide:19-40 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P27546 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526714|uniprotkb:Q05BJ2|uniprotkb:Q3UIS2|uniprotkb:Q3UUH5|uniprotkb:Q3UY36|uniprotkb:Q7TPC6|uniprotkb:Q7TPD4|uniprotkb:Q80YQ5|uniprotkb:Q8CFP5|ensembl:ENSMUSP00000035055 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:map4_mouse(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)|uniprotkb:Mtap4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001192259.1|refseq:NP_001192261.1|refseq:NP_032659.2|ensembl:ENSMUSG00000032479(gene)|ensembl:ENSMUST00000035055(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27546|go:"GO:0043005"(neuron projection)|refseq:NP_001298092.1|refseq:NP_001298093.1|refseq:XP_017168653.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:DVblnhNfUaxX6rpvxn660Pq09L410090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:496-514|identified peptide:240-271|identified peptide:604-625 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P27659 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526690|uniprotkb:O89071|uniprotkb:Q91VJ6|ensembl:ENSMUSP00000080354 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rl3_mouse(display_long)|uniprotkb:Rpl3(gene name)|psi-mi:Rpl3(display_short)|uniprotkb:J1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_038790.2|ensembl:ENSMUSG00000060036(gene)|ensembl:ENSMUST00000081650(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P27659|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:GrC8OWBLXBaBuOrzEOvyR6cid1A10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:313-334|identified peptide:201-224|identified peptide:199-224 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q99020 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-299641|ensembl:ENSMUSP00000074238|uniprotkb:Q8BPE0 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:roaa_mouse(display_long)|uniprotkb:Hnrnpab(gene name)|psi-mi:Hnrnpab(display_short)|uniprotkb:Cbf-a(gene name synonym)|uniprotkb:Cgbfa(gene name synonym)|uniprotkb:Hnrpab(gene name synonym)|uniprotkb:CArG-binding factor-A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 ensembl:ENSMUSG00000020358(gene)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|ensembl:ENSMUST00000074669(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|mint:Q99020|refseq:NP_034578.1|dip:DIP-31415N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:ltjLRkaO2WQfLDwCtMB3T0HGqdM10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:259-271|identified peptide:77-88|identified peptide:161-174|identified peptide:177-195 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q9DCH4 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-1634316|uniprotkb:Q5XJV3|ensembl:ENSMUSP00000033342 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:eif3f_mouse(display_long)|uniprotkb:Eif3f(gene name)|psi-mi:Eif3f(display_short)|uniprotkb:Eif3s5(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_079620.2|dip:DIP-42766N|ensembl:ENSMUSG00000031029(gene)|ensembl:ENSMUST00000033342(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:Q9DCH4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:RTpmhLHfvqVe3dkVb7fImMfdeTA10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:266-282|identified peptide:283-301 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P99024 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-350896|uniprotkb:P05218|uniprotkb:Q3TFB6|uniprotkb:Q3THH9|uniprotkb:Q3TIL1|uniprotkb:Q3UAV4|uniprotkb:Q3UF52|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|uniprotkb:B1B178|ensembl:ENSMUSP00000001566 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:tbb5_mouse(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_035785.1|interpro:IPR023123|interpro:IPR036525|interpro:IPR018316|interpro:IPR037103|mint:P99024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518|ensembl:ENSMUSG00000001525(gene)|ensembl:ENSMUST00000001566(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045298"(tubulin complex)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:163-174|identified peptide:63-77|identified peptide:363-379|identified peptide:104-121|identified peptide:78-103 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P12970 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-773955|uniprotkb:Q91YM3|ensembl:ENSMUSP00000099962 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:rl7a_mouse(display_long)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:Rpl7a(gene name)|psi-mi:Rpl7a(display_short)|uniprotkb:Surf3(gene name synonym)|uniprotkb:Surf-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_038749.1|ensembl:ENSMUSG00000062647(gene)|ensembl:ENSMUST00000102898(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P12970|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:XRP8YT3AaHxiv41NmJygfWNtBEs10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:38-48|identified peptide:138-150|identified peptide:76-89|identified peptide:74-89 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q68FD5 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-769168|ensembl:ENSMUSP00000099475 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:clh1_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001003908.1|dip:DIP-31947N|ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000103186(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q68FD5|rcsb pdb:5ODS|reactome:R-MMU-177504|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0032051"(clathrin light chain binding) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:iHg/TOG2rWePqtsEmuc/szn/chI10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:355-366|identified peptide:1482-1498|identified peptide:1462-1481|identified peptide:1074-1094|identified peptide:246-269 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q9Z248 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526952|uniprotkb:Q6PF91|uniprotkb:Q78HB0|uniprotkb:Q8BGV1|uniprotkb:Q8CE51|ensembl:ENSMUSP00000092993 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:aebp2_mouse(display_long)|uniprotkb:Aebp2(gene name)|psi-mi:Aebp2(display_short)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 ensembl:ENSMUSG00000030232(gene)|ensembl:ENSMUST00000095350(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-MMU-212300|reactome:R-MMU-3214841|refseq:NP_001005605.1|refseq:NP_001296365.1|refseq:NP_001296366.1|refseq:NP_033767.2|refseq:NP_848918.1|refseq:XP_006506969.1|refseq:XP_006506972.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:/WahLrADSj075nV+/m/6Up+FaoI10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:234-250|identified peptide:297-310 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q6ZWX6 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:13-25|identified peptide:245-259|identified peptide:155-173 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q7TPV4 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-1373622|uniprotkb:O35851|uniprotkb:Q80Y66|uniprotkb:Q8R4X2|uniprotkb:Q99KP0|ensembl:ENSMUSP00000044827 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:mbb1a_mouse(display_long)|uniprotkb:Mybbp1a(gene name)|psi-mi:Mybbp1a(display_short)|uniprotkb:P160(gene name synonym)|uniprotkb:Myb-binding protein of 160 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_058056.2|dip:DIP-39831N|ensembl:ENSMUSG00000040463(gene)|ensembl:ENSMUST00000045633(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR016024(Armadillo-type fold)|mint:Q7TPV4|reactome:R-MMU-5250924 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:rt1TQLZB7JNBkpt3DooDAlzOYCo10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:827-837|identified peptide:1079-1091|identified peptide:1098-1112|identified peptide:1116-1131|identified peptide:1270-1287|identified peptide:32-48|identified peptide:765-797 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q920Q8 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-643239|uniprotkb:Q06BK6|uniprotkb:Q3TXI1|uniprotkb:Q3UJE3|uniprotkb:Q3UJS1|uniprotkb:Q3UKH9|uniprotkb:Q3UMK9|uniprotkb:Q6ZQ34|uniprotkb:Q99KN0|uniprotkb:Q9D978|ensembl:ENSMUSP00000023918 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:ns1bp_mouse(display_long)|uniprotkb:Kelch family protein Nd1-L(gene name synonym)|uniprotkb:ND1-L2(gene name synonym)|uniprotkb:Nd1-S(gene name synonym)|uniprotkb:Ivns1abp(gene name)|psi-mi:Ivns1abp(display_short)|uniprotkb:Kiaa0850(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:Nd1L(gene name synonym)|uniprotkb:Nd1S(gene name synonym)|uniprotkb:Ns1(gene name synonym)|uniprotkb:Ns1bp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001034600.1|refseq:NP_001034601.1|refseq:NP_473443.2|ensembl:ENSMUSG00000023150(gene)|ensembl:ENSMUST00000023918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:j5/XawL9H4va/BB/HXbIeItP7MY10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:153-172|identified peptide:75-96|identified peptide:231-256|identified peptide:205-230|identified peptide:597-638 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q62315 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:14-27|identified peptide:263-281|identified peptide:262-281 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q52L64 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526529 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:q52l64_mouse(display_long)|uniprotkb:Igkv8-30(gene name)|psi-mi:Igkv8-30(display_short)|uniprotkb:Gm10883(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 rcsb pdb:1JGV|rcsb pdb:1Q9W|rcsb pdb:2R1W|rcsb pdb:2R1X|rcsb pdb:2R1Y|rcsb pdb:2R2H|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013106(Immunoglobulin V-set)|rcsb pdb:1A3R|rcsb pdb:1H3P|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR003599(Immunoglobulin subtype)|rcsb pdb:2R2B|rcsb pdb:1JGU|rcsb pdb:3T77|rcsb pdb:1BBD|rcsb pdb:2R23|rcsb pdb:2FD6|interpro:IPR036179 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:H2IV6NmyyuPWBjJdGES8xs67pyQ10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:215-225|identified peptide:196-209|identified peptide:182-195 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:Q80U70 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:430-441|identified peptide:598-613|identified peptide:540-557|identified peptide:345-362|identified peptide:6-40 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P16546 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-911063|uniprotkb:A3KGU6|uniprotkb:Q8K380|uniprotkb:Q9CT05|uniprotkb:A3KGU8|ensembl:ENSMUSP00000092697 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:sptn1_mouse(display_long)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 dip:DIP-37712N|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000095083(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16546|reactome:R-MMU-264870|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:UVB6Kv+PBlqDH3OLoGjxm5oYVPQ10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:1350-1359|identified peptide:1940-1950|identified peptide:1547-1558|identified peptide:1033-1045|identified peptide:1099-1110|identified peptide:2455-2467|identified peptide:1972-1984|identified peptide:567-580|identified peptide:1830-1844|identified peptide:2138-2155|identified peptide:2100-2119|identified peptide:2162-2180|identified peptide:169-189|identified peptide:815-824|identified peptide:1370-1380|identified peptide:263-272|identified peptide:1608-1619|identified peptide:1633-1646|identified peptide:1068-1082|identified peptide:1501-1519|identified peptide:382-402|identified peptide:1890-1910|identified peptide:1716-1736|identified peptide:1111-1131|identified peptide:1465-1485|identified peptide:486-507|identified peptide:2018-2040|identified peptide:686-708|identified peptide:883-907 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q921E6 uniprotkb:P63260 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2526357|imex:IM-12117-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1A, Supp Table 1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 intact-crc:95933BB51292E69E|rigid:Uqyd30mcwRb6Kztap4GxDU1uhWw false flag tag:?-? identified peptide:292-312|identified peptide:19-28|identified peptide:184-191|identified peptide:40-50|identified peptide:51-61|identified peptide:29-39|identified peptide:239-254|identified peptide:69-84|identified peptide:96-113|identified peptide:147-177|identified peptide:119-147 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q62315 uniprotkb:Q921E6 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531300|imex:IM-12117-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 1B|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 intact-crc:0F41B491E5759898|rigid:113u0hV5B/6ScMAoYKGYGaPR+Uk false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q80U70 uniprotkb:Q61188 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531313|imex:IM-12117-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 go:"GO:0005634"(nucleus) - - figure legend:Fig. 1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 intact-crc:7FA02A48267360D5|rigid:2IcS3uRvPCqqdxcCohJW8lZaavU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q80U70 uniprotkb:Q62315 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531313|imex:IM-12117-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 intact-crc:7FA02A48267360D5|rigid:2IcS3uRvPCqqdxcCohJW8lZaavU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62315 uniprotkb:Q61188 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531319|imex:IM-12117-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 go:"GO:0005634"(nucleus) - - figure legend:Fig. 1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 intact-crc:7708788A75C6DB68|rigid:2IcS3uRvPCqqdxcCohJW8lZaavU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62315 uniprotkb:Q80U70 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531319|imex:IM-12117-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 intact-crc:7708788A75C6DB68|rigid:2IcS3uRvPCqqdxcCohJW8lZaavU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61188 uniprotkb:Q62315 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531325|imex:IM-12117-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 intact-crc:1485799BF94079EE|rigid:2IcS3uRvPCqqdxcCohJW8lZaavU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61188 uniprotkb:Q80U70 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531325|imex:IM-12117-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 intact-crc:1485799BF94079EE|rigid:2IcS3uRvPCqqdxcCohJW8lZaavU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q921E6 uniprotkb:Q61188 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531338|imex:IM-12117-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 go:"GO:0005634"(nucleus) - - figure legend:Fig. 1D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 intact-crc:D9CB49AF66D0537E|rigid:5GkJRa/e6MSEzorS3TXzMX1fBRA false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q921E6 uniprotkb:Q62315 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531338|imex:IM-12117-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 intact-crc:D9CB49AF66D0537E|rigid:5GkJRa/e6MSEzorS3TXzMX1fBRA false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q921E6 uniprotkb:Q80U70 intact:EBI-904301|uniprotkb:P97462|ensembl:ENSMUSP00000102853|ensembl:ENSMUSP00000159149 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 psi-mi:eed_mouse(display_long)|uniprotkb:Eed(gene name)|psi-mi:Eed(display_short) psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2531338|imex:IM-12117-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068676.1|dip:DIP-29523N|ensembl:ENSMUSG00000030619(gene)|ensembl:ENSMUST00000107234(transcript)|ensembl:ENSMUST00000238981(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045120"(pronucleus)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q921E6|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750 refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N go:"GO:0005634"(nucleus) - - figure legend:Fig. 1D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell) - 2010/01/04 2014/10/16 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA10090 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 intact-crc:D9CB49AF66D0537E|rigid:5GkJRa/e6MSEzorS3TXzMX1fBRA false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62315 uniprotkb:Q80U70 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2531426|imex:IM-12117-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N psi-mi:"MI:0469"(intact) - - figure legend:Figs. 2A, 2C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/04 2014/10/16 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 intact-crc:D691655FD0C7F367|rigid:ROlOLHWdhH/RqtKgTJTSkZmUz1Q false glutathione s tranferase tag:?-?|necessary binding region:726-913 his tag:?-?|sufficient binding region:1-185|sufficient binding region:185-370 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q80U70 uniprotkb:Q3UXZ9 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 intact:EBI-2531441|uniprotkb:Q3TM94|uniprotkb:Q3UMI5|uniprotkb:Q66JZ3|ensembl:ENSMUSP00000005108 psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:kdm5a_mouse(display_long)|uniprotkb:Kdm5a(gene name)|psi-mi:Kdm5a(display_short)|uniprotkb:Jarid1a(gene name synonym)|uniprotkb:Rbp2(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:"MI:0096"(pull down) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2531486|imex:IM-12117-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|ensembl:ENSMUSG00000030180(gene)|ensembl:ENSMUST00000005108(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|reactome:R-MMU-3214842|refseq:NP_666109.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/04 2014/10/16 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 rogid:8C0wFfScuniM5xlbNl2gqSHc++U10090 intact-crc:B2669C9A0E4507C0|rigid:IyPxT9j7AbivAwsp+SntgC/kEi4 false his tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:250-500 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q80U70 uniprotkb:Q3UXZ9 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 intact:EBI-2531441|uniprotkb:Q3TM94|uniprotkb:Q3UMI5|uniprotkb:Q66JZ3|ensembl:ENSMUSP00000005108 psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:kdm5a_mouse(display_long)|uniprotkb:Kdm5a(gene name)|psi-mi:Kdm5a(display_short)|uniprotkb:Jarid1a(gene name synonym)|uniprotkb:Rbp2(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:"MI:0096"(pull down) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2531357|imex:IM-12117-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|ensembl:ENSMUSG00000030180(gene)|ensembl:ENSMUST00000005108(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|reactome:R-MMU-3214842|refseq:NP_666109.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/04 2014/10/16 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 rogid:8C0wFfScuniM5xlbNl2gqSHc++U10090 intact-crc:9F16D0B2DA6F26AB|rigid:IyPxT9j7AbivAwsp+SntgC/kEi4 false his tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:250-500|mutation disrupting interaction:423-423,420-420,422-422 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62315 uniprotkb:Q80U70 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692 psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Peng et al. (2009) imex:IM-12117|pubmed:20064375 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2531370|imex:IM-12117-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2B|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/01/04 2014/10/16 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 rogid:yULk8oVce1HyiORkV/CZmoSb63010090 intact-crc:D9439B3752D4F5C4|rigid:ROlOLHWdhH/RqtKgTJTSkZmUz1Q false glutathione s tranferase tag:?-?|necessary binding region:726-913|mutation disrupting interaction:873-873,875-875,876-876 his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)