#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P05771	uniprotkb:Q42384	intact:EBI-706216|uniprotkb:O43744|uniprotkb:P05127|uniprotkb:Q15138|uniprotkb:Q93060|uniprotkb:Q9UE49|uniprotkb:Q9UE50|uniprotkb:Q9UEH8|uniprotkb:Q9UJ30|uniprotkb:Q9UJ33|uniprotkb:C5IFJ8|intact:EBI-3396567|uniprotkb:D3DWF5|ensembl:ENSP00000318315	intact:EBI-1382964|ensemblplants:AT4G15900.1	psi-mi:kpcb_human(display_long)|uniprotkb:PRKCB1(gene name synonym)|uniprotkb:PKCB(gene name synonym)|uniprotkb:PRKCB(gene name)|psi-mi:PRKCB(display_short)	psi-mi:prl1_arath(display_long)|uniprotkb:PRL1(gene name)|psi-mi:PRL1(display_short)|uniprotkb:At4g15900(locus name)|uniprotkb:dl3990w(orf name)|uniprotkb:MAC2(gene name synonym)|uniprotkb:MOS4-associated complex protein 2(gene name synonym)|uniprotkb:FCAALL.40(orf name)	psi-mi:"MI:0096"(pull down)	Nemeth et al. (1998)	pubmed:9765207|imex:IM-19042	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1644666|imex:IM-19042-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002729.2|refseq:NP_997700.1|dip:DIP-34187N|ensembl:ENSG00000166501(gene)|ensembl:ENST00000321728(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007165"(signal transduction)|go:"GO:0008091"(spectrin)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035408"(histone H3-T6 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042113"(B cell activation)|go:"GO:0042393"(histone binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044305"(calyx of Held)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034664|interpro:IPR035892|rcsb pdb:2I0E|reactome:R-HSA-114516|reactome:R-HSA-1169091|reactome:R-HSA-416993|reactome:R-HSA-418597|reactome:R-HSA-4419969|reactome:R-HSA-5099900|reactome:R-HSA-5218921|reactome:R-HSA-5668599|reactome:R-HSA-76005|reactome:R-HSA-8939246	refseq:NP_193325.1|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|ensemblplants:AT4G15900(gene)|ensemblplants:AT4G15900.1(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0009749"(response to glucose)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010154"(fruit development)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048364"(root development)|go:"GO:0048366"(leaf development)|go:"GO:0048825"(cotyledon development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	-	-	-	figure legend:Figure 4e|comment:"The authors stated that \"Because PKC-beta I and beta II sequences only differed by 52 carboxy-terminal amino acids (Kubo et al. 1987), the data also indicated that the carboxyl terminus of PKC-beta II was required for PRL1-binding\"."|caution:The expressed in annotation for the P05771 protein is spofr-sf_21, although the authors only state the protein was expressed in an insect based protein expression system. I have assumed this is based on the spofr-sf_21 cell expression system.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/03/03	2014/10/16	rogid:racpanFwAtAbFzE9i3iiHQBPCyg9606	rogid:DHIuqlSZSCA6gIlKWKGheBqJCxA3702	intact-crc:589EF0F593133EFE|rigid:jiM7WhXwZDsRuRpO4CebtS/tct0	false	-	sufficient binding region:1-330|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O04294	uniprotkb:Q42384	intact:EBI-1644689|uniprotkb:O04255|uniprotkb:Q94F55|intact:EBI-6368711|uniprotkb:O49601|uniprotkb:Q4JHM3|ensemblplants:AT4G02150.1	intact:EBI-1382964|ensemblplants:AT4G15900.1	psi-mi:impa3_arath(display_long)|uniprotkb:IMPA3(gene name)|psi-mi:IMPA3(display_short)|uniprotkb:KAP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:MOS6(gene name synonym)|uniprotkb:Protein MODIFIER OF SNC1 6(gene name synonym)|uniprotkb:T10M13.16(orf name)|uniprotkb:At4g02150(locus name)	psi-mi:prl1_arath(display_long)|uniprotkb:PRL1(gene name)|psi-mi:PRL1(display_short)|uniprotkb:At4g15900(locus name)|uniprotkb:dl3990w(orf name)|uniprotkb:MAC2(gene name synonym)|uniprotkb:MOS4-associated complex protein 2(gene name synonym)|uniprotkb:FCAALL.40(orf name)	psi-mi:"MI:0018"(two hybrid)	Nemeth et al. (1998)	pubmed:9765207|imex:IM-19042	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1644685|imex:IM-19042-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_192124.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR024931|interpro:IPR032413|rcsb pdb:4TNM|interpro:IPR036975|ensemblplants:AT4G02150(gene)|ensemblplants:AT4G02150.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)	refseq:NP_193325.1|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|ensemblplants:AT4G15900(gene)|ensemblplants:AT4G15900.1(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0009749"(response to glucose)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010154"(fruit development)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048364"(root development)|go:"GO:0048366"(leaf development)|go:"GO:0048825"(cotyledon development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/03/03	2014/10/16	rogid:OU025BkGbX7G6nkiRw2wQcI4Dlw3702	rogid:DHIuqlSZSCA6gIlKWKGheBqJCxA3702	intact-crc:1FCD883BD953D45A|rigid:pFWDY5Pqr5FztfrCMr/cQqc0l5M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O04294	uniprotkb:Q42384	intact:EBI-1644689|uniprotkb:O04255|uniprotkb:Q94F55|intact:EBI-6368711|uniprotkb:O49601|uniprotkb:Q4JHM3|ensemblplants:AT4G02150.1	intact:EBI-1382964|ensemblplants:AT4G15900.1	psi-mi:impa3_arath(display_long)|uniprotkb:IMPA3(gene name)|psi-mi:IMPA3(display_short)|uniprotkb:KAP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:MOS6(gene name synonym)|uniprotkb:Protein MODIFIER OF SNC1 6(gene name synonym)|uniprotkb:T10M13.16(orf name)|uniprotkb:At4g02150(locus name)	psi-mi:prl1_arath(display_long)|uniprotkb:PRL1(gene name)|psi-mi:PRL1(display_short)|uniprotkb:At4g15900(locus name)|uniprotkb:dl3990w(orf name)|uniprotkb:MAC2(gene name synonym)|uniprotkb:MOS4-associated complex protein 2(gene name synonym)|uniprotkb:FCAALL.40(orf name)	psi-mi:"MI:0018"(two hybrid)	Nemeth et al. (1998)	pubmed:9765207|imex:IM-19042	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1644709|imex:IM-19042-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_192124.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR024931|interpro:IPR032413|rcsb pdb:4TNM|interpro:IPR036975|ensemblplants:AT4G02150(gene)|ensemblplants:AT4G02150.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)	refseq:NP_193325.1|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|ensemblplants:AT4G15900(gene)|ensemblplants:AT4G15900.1(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0009749"(response to glucose)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010154"(fruit development)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048364"(root development)|go:"GO:0048366"(leaf development)|go:"GO:0048825"(cotyledon development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	-	-	-	figure legend:Figure 7b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/03/03	2014/10/16	rogid:OU025BkGbX7G6nkiRw2wQcI4Dlw3702	rogid:DHIuqlSZSCA6gIlKWKGheBqJCxA3702	intact-crc:019387E2704918A7|rigid:pFWDY5Pqr5FztfrCMr/cQqc0l5M	false	sufficient binding region:380-531	sufficient binding region:413-486	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q42384	uniprotkb:O04294	intact:EBI-1382964|ensemblplants:AT4G15900.1	intact:EBI-1644689|uniprotkb:O04255|uniprotkb:Q94F55|intact:EBI-6368711|uniprotkb:O49601|uniprotkb:Q4JHM3|ensemblplants:AT4G02150.1	psi-mi:prl1_arath(display_long)|uniprotkb:PRL1(gene name)|psi-mi:PRL1(display_short)|uniprotkb:At4g15900(locus name)|uniprotkb:dl3990w(orf name)|uniprotkb:MAC2(gene name synonym)|uniprotkb:MOS4-associated complex protein 2(gene name synonym)|uniprotkb:FCAALL.40(orf name)	psi-mi:impa3_arath(display_long)|uniprotkb:IMPA3(gene name)|psi-mi:IMPA3(display_short)|uniprotkb:KAP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:MOS6(gene name synonym)|uniprotkb:Protein MODIFIER OF SNC1 6(gene name synonym)|uniprotkb:T10M13.16(orf name)|uniprotkb:At4g02150(locus name)	psi-mi:"MI:0096"(pull down)	Nemeth et al. (1998)	pubmed:9765207|imex:IM-19042	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1644798|imex:IM-19042-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_193325.1|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|ensemblplants:AT4G15900(gene)|ensemblplants:AT4G15900.1(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0009749"(response to glucose)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010154"(fruit development)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048364"(root development)|go:"GO:0048366"(leaf development)|go:"GO:0048825"(cotyledon development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	refseq:NP_192124.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR024931|interpro:IPR032413|rcsb pdb:4TNM|interpro:IPR036975|ensemblplants:AT4G02150(gene)|ensemblplants:AT4G02150.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)	-	-	-	figure legend:Figure 7c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/03/03	2014/10/16	rogid:DHIuqlSZSCA6gIlKWKGheBqJCxA3702	rogid:OU025BkGbX7G6nkiRw2wQcI4Dlw3702	intact-crc:85BB992ABFF67A85|rigid:pFWDY5Pqr5FztfrCMr/cQqc0l5M	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)