#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10083	uniprotkb:Q01069	intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1632200|imex:IM-24788-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:FE451F9757C626A0|rigid:r+W6tQnjFfKPXIRcbrNcYmVx4kM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:P10083	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639060|imex:IM-24788-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Ac"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227	intact-crc:9EFB08A573F69DB2|rigid:r+W6tQnjFfKPXIRcbrNcYmVx4kM	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10084	uniprotkb:Q01069	intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639075|imex:IM-24788-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Sc"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:3399A77CFBE0016B|rigid:H3Ru9XtednhAnd+u4pJGgBSIaoA	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09775	uniprotkb:Q01069	intact:EBI-143216|uniprotkb:Q541C1|intact:EBI-1639086|uniprotkb:Q9W5G2|ensemblmetazoa:FBpp0070074	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:ast8_drome(display_long)|uniprotkb:ase(gene name)|psi-mi:ase(display_short)|uniprotkb:T8(gene name synonym)|uniprotkb:CG3258(orf name)|uniprotkb:Protein asense(gene name synonym)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639090|imex:IM-24788-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476694.1|flybase:FBgn0000137|dip:DIP-636N|ensemblmetazoa:FBgn0000137(gene)|ensemblmetazoa:FBtr0070075(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Ase"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP02+bVS+GOKM/86SHrcITamzMg7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:5B3AD3B703B80343|rigid:YpbW7nw+Px9BV5HTHzZAkBzLoq0	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:P11420	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639101|imex:IM-24788-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Da"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	intact-crc:8CFD7CAC581DDC7D|rigid:LznnBWQJKxwBrV2J20kzR2vRwso	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:P16371	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639112|imex:IM-24788-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	intact-crc:5C416257C5BA7597|rigid:u7owkvMArFfGg7pk9LB64E61QvE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01070	uniprotkb:P10083	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639123|imex:IM-24788-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Ac"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227	intact-crc:B4B8D48B50A20BA7|rigid:BscKRXroS0RvCUqiOS2AcXmeH2A	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10084	uniprotkb:Q01070	intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639130|imex:IM-24788-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Sc"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:0417A516892A1D3B|rigid:vcyQnCzzE27X4oIsRIY5Z9nI8QA	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09775	uniprotkb:Q01070	intact:EBI-143216|uniprotkb:Q541C1|intact:EBI-1639086|uniprotkb:Q9W5G2|ensemblmetazoa:FBpp0070074	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:ast8_drome(display_long)|uniprotkb:ase(gene name)|psi-mi:ase(display_short)|uniprotkb:T8(gene name synonym)|uniprotkb:CG3258(orf name)|uniprotkb:Protein asense(gene name synonym)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639137|imex:IM-24788-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476694.1|flybase:FBgn0000137|dip:DIP-636N|ensemblmetazoa:FBgn0000137(gene)|ensemblmetazoa:FBtr0070075(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Ase"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP02+bVS+GOKM/86SHrcITamzMg7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:4A113E49A86FFAD1|rigid:NzfkqoMtX72PHMjIH3G40tFx7ZM	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11420	uniprotkb:Q01070	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639144|imex:IM-24788-141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Da"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:FE6DF5AA5989E0E5|rigid:9iV8oTfcearZ1v8n18VopzyBlkk	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01070	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639151|imex:IM-24788-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:B8CB88EF2EA9F8AA|rigid:WgD2BjRlbQNfPtE2Yl8em/uxJy0	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:P10083	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639158|imex:IM-24788-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Ac"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227	intact-crc:517800A8CE8C03A3|rigid:lQEnp3iFb6sxR0+SxlPX5YL7ETk	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:P10084	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639169|imex:IM-24788-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Sc"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227	intact-crc:FBD124341741C601|rigid:YW33YvssDEHvawZNQpYRD92ldcI	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:P09775	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-143216|uniprotkb:Q541C1|intact:EBI-1639086|uniprotkb:Q9W5G2|ensemblmetazoa:FBpp0070074	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:ast8_drome(display_long)|uniprotkb:ase(gene name)|psi-mi:ase(display_short)|uniprotkb:T8(gene name synonym)|uniprotkb:CG3258(orf name)|uniprotkb:Protein asense(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639176|imex:IM-24788-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_476694.1|flybase:FBgn0000137|dip:DIP-636N|ensemblmetazoa:FBgn0000137(gene)|ensemblmetazoa:FBtr0070075(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Ase"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:UP02+bVS+GOKM/86SHrcITamzMg7227	intact-crc:DC4C036353A4C2AF|rigid:qjnMl4CAmJzRH3Dqyg96LijjKX0	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11420	uniprotkb:P13097	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639183|imex:IM-24788-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Da"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	intact-crc:3D21BEE90223AE2F|rigid:VtIQhW+NbemXXLLZBBNCZoao+k8	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:P13097	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639190|imex:IM-24788-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	intact-crc:B509DEDF1250D15E|rigid:LVe75VmaZH4IeAt6bq8SCx6nSy4	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11420	uniprotkb:P13096	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639201|imex:IM-24788-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:Da"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	intact-crc:BFD42980F1A8E7F5|rigid:du/cn/eubJ8yQaG8+rACRkzwbXw	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11420	uniprotkb:P13098	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639215|imex:IM-24788-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Da"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:D645E1AF01DD58FC|rigid:oR2k/cUFx7uFKhKd0Tjj7HNvDbo	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:P16371	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639208|imex:IM-24788-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	intact-crc:C7975DB522017458|rigid:NB7VkUKEONT8sGDvRduKblR5sz0	false	mutation disrupting interaction:178-178	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:P13098	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639226|imex:IM-24788-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:AC244D98152C963A|rigid:aG8n1lgmsxs2HDTWdppsnorhYlM	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10083	uniprotkb:Q01068	intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639237|imex:IM-24788-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Ac"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:376080E40613DB1B|rigid:nko2XLosc+nbcEr6U5ivLICHNAI	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:P10084	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639244|imex:IM-24788-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Sc"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227	intact-crc:9DC9A478DFDE1EB9|rigid:dHLAxjwEUTz+vNq6ISMH0PPWw5o	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:P09775	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-143216|uniprotkb:Q541C1|intact:EBI-1639086|uniprotkb:Q9W5G2|ensemblmetazoa:FBpp0070074	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:ast8_drome(display_long)|uniprotkb:ase(gene name)|psi-mi:ase(display_short)|uniprotkb:T8(gene name synonym)|uniprotkb:CG3258(orf name)|uniprotkb:Protein asense(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639251|imex:IM-24788-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_476694.1|flybase:FBgn0000137|dip:DIP-636N|ensemblmetazoa:FBgn0000137(gene)|ensemblmetazoa:FBtr0070075(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Ase"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:UP02+bVS+GOKM/86SHrcITamzMg7227	intact-crc:24AA1BE31F6C5D77|rigid:qVP8qiMCgWcDeMES49jSqBNkHhc	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:Q01068	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639258|imex:IM-24788-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:M3"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:7ADF2EE7C37C0410|rigid:TzRJeDHWarXwAfWT8xy7hHIsfFY	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01068	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639265|imex:IM-24788-147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:B3D068F3C605EE66|rigid:3QBkDXhuNiga+rIlGlBzxdbuDME	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01071	uniprotkb:Q01068	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639276|imex:IM-24788-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:M3"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:CC6AB69F9A0D7BA5|rigid:Idfi4dKr7EXPlayUryWfLdl3FYw	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01071	uniprotkb:P16371	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639283|imex:IM-24788-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:Gro"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	intact-crc:67579573CFD5C355|rigid:90UFTROEFoUh/uUmYVgpzwZWrBE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01068	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639290|imex:IM-24788-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:M3"|figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:D23EAD0A2D84A984|rigid:3QBkDXhuNiga+rIlGlBzxdbuDME	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:Q01069	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639297|imex:IM-24788-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:63DE6C5F85D307E4|rigid:0sYxSim3vF/wf1PUgcskMqoCN08	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:Q01070	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639304|imex:IM-24788-149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:2A42E6639E273178|rigid:S+Hz4ISxD5WpqGrmjXyPSG9DcUk	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:Q01069	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639311|imex:IM-24788-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:C0A92D4394E0AD55|rigid:h24FO09X7moaln/v9Mpm+Lx9dfo	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:P13098	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639318|imex:IM-24788-151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:5CF316F084CD94EE|rigid:H6ZoHMjO48b4GRDqZevyou3Zy7Q	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:Q01071	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639325|imex:IM-24788-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:CDF85F8627AF6863|rigid:uTUgxMob5c8WzsHjrdxDr3Ne3zU	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:P48987	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-1639335|uniprotkb:A0AQ36|uniprotkb:A0AQ37|uniprotkb:A0AQ43|uniprotkb:Q9VHU0|ensemblmetazoa:FBpp0081318	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:ato_drome(display_long)|uniprotkb:ato(gene name)|psi-mi:ato(display_short)|uniprotkb:CG7508(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639332|imex:IM-24788-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_731223.1|flybase:FBgn0010433|dip:DIP-151N|ensemblmetazoa:FBgn0010433(gene)|ensemblmetazoa:FBtr0081828(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007460"(R8 cell fate commitment)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008038"(neuron recognition)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048801"(antennal joint morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:Mbeta  ;  PREY Protein:Ato"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:idcKcfXTlBLN/Xxf7X/15gfxGag7227	intact-crc:2DBDA724B0BB7128|rigid:Vpq4fzUBfPA9wlyjMybJ3lNlI1Y	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01070	uniprotkb:Q01069	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639343|imex:IM-24788-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:1D800EC3BE401D0B|rigid:S+Hz4ISxD5WpqGrmjXyPSG9DcUk	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01070	uniprotkb:Q01070	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639350|imex:IM-24788-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:D526A9FBFBD642D9|rigid:V1+NTRFNPNdpmJ2RPG86yR+H828	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:Q01070	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639357|imex:IM-24788-153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:98680DD2B6451DF8|rigid:TBOZGQwDdlVhJr/H+TCzznV5RKU	false	fusion protein:?-?|mutation decreasing interaction:178-178	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:Q01070	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639364|imex:IM-24788-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:3FA98AE9055530C9|rigid:KtZRWJAIf0WqjTGhYxGz84KYEVk	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01070	uniprotkb:Q01071	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639371|imex:IM-24788-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Mgamma  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:D9191E8D3828F980|rigid:+nrt/BZm0j/kdZMQZ4D1ZMfdEBE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:Q01069	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639378|imex:IM-24788-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:220CEAB7B499EC11|rigid:2blLeqkWiDPu3HW0+AzaFpxN9wQ	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:Q01070	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639385|imex:IM-24788-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:1BB0B3E2FEF072B6|rigid:JSn3UiRaRpS3u1A1p/ZzPpJRMtE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:P13097	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639392|imex:IM-24788-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	intact-crc:5E686A984652E6FB|rigid:6Bt5tbfQyPg48Bb6QV6eivlENy8	false	fusion protein:?-?|mutation decreasing interaction:178-178	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:P13098	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639399|imex:IM-24788-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:EB06754EC1C38706|rigid:gRy3QahZGWyRQ6e8lR05HlgmQAQ	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13097	uniprotkb:Q01071	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639406|imex:IM-24788-155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:04ED95E9917EF107|rigid:ByZbS+Epeh0TZbjEuRZEwkaHX1s	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48987	uniprotkb:P13097	intact:EBI-1639335|uniprotkb:A0AQ36|uniprotkb:A0AQ37|uniprotkb:A0AQ43|uniprotkb:Q9VHU0|ensemblmetazoa:FBpp0081318	intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334	psi-mi:ato_drome(display_long)|uniprotkb:ato(gene name)|psi-mi:ato(display_short)|uniprotkb:CG7508(orf name)	psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639413|imex:IM-24788-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_731223.1|flybase:FBgn0010433|dip:DIP-151N|ensemblmetazoa:FBgn0010433(gene)|ensemblmetazoa:FBtr0081828(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007460"(R8 cell fate commitment)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008038"(neuron recognition)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048801"(antennal joint morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M7  ;  PREY Protein:Ato"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:idcKcfXTlBLN/Xxf7X/15gfxGag7227	rogid:ko+76awzLWRJNBn06B3PQZWBhf47227	intact-crc:5174BACE0DDDF176|rigid:IyVr0XFAeBraN6B1c/AW6OY7Uzw	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:P13096	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639420|imex:IM-24788-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	intact-crc:CB79382937F3DC40|rigid:h24FO09X7moaln/v9Mpm+Lx9dfo	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:Q01070	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639427|imex:IM-24788-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:6DE9C63060731886|rigid:TBOZGQwDdlVhJr/H+TCzznV5RKU	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:P13096	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639434|imex:IM-24788-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	intact-crc:01390B50A2BD9CF8|rigid:q2hn4AytlkTCCeqOKUezKhY7b60	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:P13098	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639441|imex:IM-24788-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:D5851F7E90668150|rigid:SDcf05o6jOS+n+F7l5xiudZtNII	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:Q01071	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639448|imex:IM-24788-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:M5  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:72B4E03B0FFD9B37|rigid:Fh7DW6UeyuhD3rIaB/DW6mnfWYQ	false	mutation decreasing interaction:178-178	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:Q01069	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639455|imex:IM-24788-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:4A40339A27DEEB6D|rigid:H6ZoHMjO48b4GRDqZevyou3Zy7Q	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:Q01070	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639462|imex:IM-24788-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:5198FF3BD36335B1|rigid:KtZRWJAIf0WqjTGhYxGz84KYEVk	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:P13098	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639469|imex:IM-24788-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:B50C35DE45AC1028|rigid:SDcf05o6jOS+n+F7l5xiudZtNII	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:P13098	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639476|imex:IM-24788-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:16953249BD84E315|rigid:D41d3MiD7VFECpcale62u6PqJj4	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:Q01071	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639483|imex:IM-24788-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:4EC5D930BCEDB600|rigid:jbLXk5fRXdUdJEdDfe9RQzyGj9k	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:Q01068	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639490|imex:IM-24788-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:1887B479446A07B5|rigid:/dBseFR+K3sZwu1fpAJ59d1Bh2s	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01070	uniprotkb:Q01068	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639497|imex:IM-24788-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:F34A38BC3000815D|rigid:mgwGWbomtZ9TOJTTaIRN3XDpGgk	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:P13096	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639504|imex:IM-24788-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	intact-crc:3870EAD48ECD3E43|rigid:0r221Mdy8tSq8QD+psrDJCPQHkg	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48987	uniprotkb:Q01068	intact:EBI-1639335|uniprotkb:A0AQ36|uniprotkb:A0AQ37|uniprotkb:A0AQ43|uniprotkb:Q9VHU0|ensemblmetazoa:FBpp0081318	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:ato_drome(display_long)|uniprotkb:ato(gene name)|psi-mi:ato(display_short)|uniprotkb:CG7508(orf name)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639518|imex:IM-24788-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_731223.1|flybase:FBgn0010433|dip:DIP-151N|ensemblmetazoa:FBgn0010433(gene)|ensemblmetazoa:FBtr0081828(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007460"(R8 cell fate commitment)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008038"(neuron recognition)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048801"(antennal joint morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Ato"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:idcKcfXTlBLN/Xxf7X/15gfxGag7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:90C2DF9179551DBF|rigid:JIFhshq9uYp/glJrmGTXbdeKt2I	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:Q01071	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639511|imex:IM-24788-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:EC171EB75F8E02EC|rigid:Idfi4dKr7EXPlayUryWfLdl3FYw	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01069	uniprotkb:Q01071	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639525|imex:IM-24788-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:3F40415FA3DCFC77|rigid:uTUgxMob5c8WzsHjrdxDr3Ne3zU	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13096	uniprotkb:Q01071	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639539|imex:IM-24788-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:74759133CA7EE27D|rigid:Fh7DW6UeyuhD3rIaB/DW6mnfWYQ	false	fusion protein:?-?|mutation decreasing interaction:178-178	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01071	uniprotkb:Q01070	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639532|imex:IM-24788-157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:F39F0B5E63C43F17|rigid:+nrt/BZm0j/kdZMQZ4D1ZMfdEBE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:Q01071	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639546|imex:IM-24788-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:D3B41608796ECF4C|rigid:jbLXk5fRXdUdJEdDfe9RQzyGj9k	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01071	uniprotkb:Q01071	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639553|imex:IM-24788-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Mdelta  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:017FED49796B2022|rigid:+NIRqitz5D9QPwlAbqX2u0SXDpc	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01069	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639560|imex:IM-24788-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:Mbeta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227	intact-crc:3695635303D7D8EF|rigid:u7owkvMArFfGg7pk9LB64E61QvE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01070	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-119159|intact:EBI-1639119|uniprotkb:Q01898|uniprotkb:Q5S4K4|ensemblmetazoa:FBpp0084329	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esmc_drome(display_long)|uniprotkb:"E(spl)mgamma-HLH"(gene name)|psi-mi:"E(spl)mgamma-HLH"(display_short)|uniprotkb:HLHmgamma(gene name synonym)|uniprotkb:Split locus enhancer protein mB(gene name synonym)|uniprotkb:CG8333(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639567|imex:IM-24788-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524504.2|flybase:FBgn0002735|ensemblmetazoa:FBgn0002735(gene)|ensemblmetazoa:FBtr0084955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-723N	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:Mgamma"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:7X93pYBqrB9eM+hgwXwFB3cIlcE7227	intact-crc:BCBE91EDAF92551B|rigid:WgD2BjRlbQNfPtE2Yl8em/uxJy0	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:P13096	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639574|imex:IM-24788-161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:M5"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227	intact-crc:10F575CB1FDB7446|rigid:NB7VkUKEONT8sGDvRduKblR5sz0	false	-	fusion protein:?-?|mutation disrupting interaction:178-178	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13098	uniprotkb:P16371	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639581|imex:IM-24788-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:M8"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	intact-crc:2B9B65E62668EFC5|rigid:aG8n1lgmsxs2HDTWdppsnorhYlM	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01071	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639588|imex:IM-24788-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:Mdelta"|figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227	intact-crc:5099C10482BAE898|rigid:90UFTROEFoUh/uUmYVgpzwZWrBE	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11420	uniprotkb:P13098	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639602|imex:IM-24788-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Da"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:97439CEE6AEBE044|rigid:oR2k/cUFx7uFKhKd0Tjj7HNvDbo	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:P13098	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639609|imex:IM-24788-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M8  ;  PREY Protein:Gro"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227	intact-crc:6485783DA591380C|rigid:aG8n1lgmsxs2HDTWdppsnorhYlM	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10083	uniprotkb:Q01068	intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639616|imex:IM-24788-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Ac"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:2115B03D36ABA47E|rigid:nko2XLosc+nbcEr6U5ivLICHNAI	false	fusion protein:?-?	sufficient binding region:1-77	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:P09775	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-143216|uniprotkb:Q541C1|intact:EBI-1639086|uniprotkb:Q9W5G2|ensemblmetazoa:FBpp0070074	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:ast8_drome(display_long)|uniprotkb:ase(gene name)|psi-mi:ase(display_short)|uniprotkb:T8(gene name synonym)|uniprotkb:CG3258(orf name)|uniprotkb:Protein asense(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639630|imex:IM-24788-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_476694.1|flybase:FBgn0000137|dip:DIP-636N|ensemblmetazoa:FBgn0000137(gene)|ensemblmetazoa:FBtr0070075(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Ase"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:UP02+bVS+GOKM/86SHrcITamzMg7227	intact-crc:4978ED4D55F9C5DB|rigid:qVP8qiMCgWcDeMES49jSqBNkHhc	false	sufficient binding region:1-77	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01068	uniprotkb:P10084	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639623|imex:IM-24788-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Sc"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227	intact-crc:E373A53D37242F2F|rigid:dHLAxjwEUTz+vNq6ISMH0PPWw5o	false	sufficient binding region:1-77	fusion protein:?-?|mutation increasing interaction:340-340	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:Q01068	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639637|imex:IM-24788-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N	-	-	-	author-identifiers:"BAIT Protein:M3  ;  PREY Protein:Gro"|figure legend:Table 1|caution:The enzyme assay was not done for interactions involving mutant M3 baits , however the colony was white indicating no reporter gene expression|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227	intact-crc:03F89F74E4939462|rigid:3QBkDXhuNiga+rIlGlBzxdbuDME	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18491	uniprotkb:P10084	intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477	intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072	psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name)	psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639644|imex:IM-24788-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation)	refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	-	-	-	author-identifiers:"BAIT Protein:Emc  ;  PREY Protein:Sc"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227	rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227	intact-crc:EB1E90678F7735F8|rigid:vlm7j3+GkJO8P6lezqqdH14O9YI	false	-	fusion protein:?-?|mutation decreasing interaction:340-340	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11420	uniprotkb:P18491	intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505	intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477	psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name)	psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639655|imex:IM-24788-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N	interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation)	-	-	-	author-identifiers:"BAIT Protein:Emc  ;  PREY Protein:Da"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227	rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227	intact-crc:A37A2F8957E83255|rigid:ofEQuiBLSqLFyIBF9DPUXHlSpz0	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14003	uniprotkb:P16371	intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short)	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639666|imex:IM-24788-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	-	-	-	author-identifiers:"BAIT Protein:Hairy  ;  PREY Protein:Gro"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:bO023bTsk72HhqvmgSjLEIotrDw7227	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	intact-crc:3B19C52C00BFF934|rigid:FHdrglr3JteKqIwUuxGzJp7BT8k	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16371	uniprotkb:P22814	intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115	intact:EBI-868309|uniprotkb:A0AVT9|uniprotkb:O76551|uniprotkb:Q6SD78|uniprotkb:Q7KPD6|uniprotkb:Q8MRF4|uniprotkb:Q9TVG1|uniprotkb:Q9TVZ7|uniprotkb:Q9TZQ9|uniprotkb:Q9TZR0|uniprotkb:Q9VRB6|intact:EBI-1639673|ensemblmetazoa:FBpp0076971|ensemblmetazoa:FBpp0311837	psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym)	psi-mi:runt_drome(display_long)|uniprotkb:run(gene name)|psi-mi:run(display_short)|uniprotkb:CG1849(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1639677|imex:IM-24788-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N	refseq:NP_001285501.1|refseq:NP_523424.2|flybase:FBgn0003300|ensemblmetazoa:FBgn0003300(gene)|ensemblmetazoa:FBtr0077279(transcript)|ensemblmetazoa:FBtr0345922(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048592"(eye morphogenesis)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|reactome:R-DME-549127|reactome:R-DME-8878166|reactome:R-DME-8931987|reactome:R-DME-8934593|reactome:R-DME-8936459|reactome:R-DME-8939236|reactome:R-DME-8939243|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|reactome:R-DME-8939902|reactome:R-DME-8940973|reactome:R-DME-8941326|reactome:R-DME-9018519	-	-	-	author-identifiers:"BAIT Protein:Gro  ;  PREY Protein:Runt"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2014/10/16	rogid:oSo29NrCWIeCi2OMusohCk64uiw7227	rogid:AhHjibxAU093Edu1nQPWbMTKGFo7227	intact-crc:11A3E1BCB22E924D|rigid:IYAdMU40RSLHUF25MILWglEJQd4	false	-	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09775	uniprotkb:P18491	intact:EBI-143216|uniprotkb:Q541C1|intact:EBI-1639086|uniprotkb:Q9W5G2|ensemblmetazoa:FBpp0070074	intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477	psi-mi:ast8_drome(display_long)|uniprotkb:ase(gene name)|psi-mi:ase(display_short)|uniprotkb:T8(gene name synonym)|uniprotkb:CG3258(orf name)|uniprotkb:Protein asense(gene name synonym)	psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name)	psi-mi:"MI:0018"(two hybrid)	Alifragis et al. (1997)	pubmed:9371806|imex:IM-24788	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1771712|imex:IM-24788-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476694.1|flybase:FBgn0000137|dip:DIP-636N|ensemblmetazoa:FBgn0000137(gene)|ensemblmetazoa:FBtr0070075(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638	interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation)	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/29	2015/11/30	rogid:UP02+bVS+GOKM/86SHrcITamzMg7227	rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227	intact-crc:8435A28B795D370E|rigid:1xNZekmmHOIOILyL2T+Ro3Nl95g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)