#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04551	uniprotkb:O74627	intact:EBI-1187862|ensemblfungi:"SPBC11B10.09.1:pep"	intact:EBI-443575|ensemblfungi:"SPBC32F12.06.1:pep"|uniprotkb:P87075	psi-mi:cdk1_schpo(display_long)|uniprotkb:cdc2(gene name)|psi-mi:cdc2(display_short)|uniprotkb:swo2(gene name synonym)|uniprotkb:SPBC11B10.09(orf name)|uniprotkb:pi002(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk1(gene name synonym)|uniprotkb:Cell division control protein 2(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)	psi-mi:cg1c_schpo(display_long)|uniprotkb:pch1(gene name)|psi-mi:pch1(display_short)|uniprotkb:SPBC32F12.06(orf name)|uniprotkb:Pombe cyclin C homolog 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Furnari et al. (1997)	pubmed:9115279|imex:IM-20154	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2026973|imex:IM-20154-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595629.1|reactome:R-SPO-176187|ensemblfungi:SPBC11B10.09(gene)|ensemblfungi:SPBC11B10.09.1(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0062123"(regulation of linear element maturation)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0072435"(response to mitotic G2 DNA damage checkpoint signaling)|go:"GO:0072441"(response to meiotic DNA replication checkpoint signaling)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0110045"(negative regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902424"(negative regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902845"(negative regulation of mitotic spindle elongation)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903380"(positive regulation of mitotic chromosome condensation)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1903467"(negative regulation of mitotic DNA replication initiation)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)|go:"GO:1904537"(negative regulation of mitotic telomere tethering at nuclear periphery)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905263"(positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:1905757"(negative regulation of primary cell septum biogenesis)|go:"GO:1905785"(negative regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990820"(response to mitotic DNA integrity checkpoint signaling)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-1076N|reactome:R-SPO-68962|reactome:R-SPO-69017|reactome:R-SPO-69202|reactome:R-SPO-68949|reactome:R-SPO-69656	ensemblfungi:SPBC32F12.06(gene)|ensemblfungi:SPBC32F12.06.1(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0023052"(signaling)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070691"(P-TEFb complex)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|reactome:R-SPO-674695|reactome:R-SPO-6796648|reactome:R-SPO-6807505|reactome:R-SPO-75955|reactome:R-SPO-9018519|refseq:NP_596149.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|mint:O74627|interpro:IPR036915|interpro:IPR043198	-	-	-	figure legend:Figure 1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/11/03	2014/10/16	rogid:Xm26f9FnmjG9I6P1hrk/9kWszzY284812	rogid:UmeTCbwP2A4WzIPgA2vRJAzBIi0284812	intact-crc:5D38DE67962E7496|rigid:T6bbMauxPg2Jtxr+b5AnTDCGJt0	false	-	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:O74627	uniprotkb:P04551	intact:EBI-443575|ensemblfungi:"SPBC32F12.06.1:pep"|uniprotkb:P87075	intact:EBI-1187862|ensemblfungi:"SPBC11B10.09.1:pep"	psi-mi:cg1c_schpo(display_long)|uniprotkb:pch1(gene name)|psi-mi:pch1(display_short)|uniprotkb:SPBC32F12.06(orf name)|uniprotkb:Pombe cyclin C homolog 1(gene name synonym)	psi-mi:cdk1_schpo(display_long)|uniprotkb:cdc2(gene name)|psi-mi:cdc2(display_short)|uniprotkb:swo2(gene name synonym)|uniprotkb:SPBC11B10.09(orf name)|uniprotkb:pi002(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk1(gene name synonym)|uniprotkb:Cell division control protein 2(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Furnari et al. (1997)	pubmed:9115279|imex:IM-20154	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2026986|imex:IM-20154-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPBC32F12.06(gene)|ensemblfungi:SPBC32F12.06.1(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0023052"(signaling)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070691"(P-TEFb complex)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|reactome:R-SPO-674695|reactome:R-SPO-6796648|reactome:R-SPO-6807505|reactome:R-SPO-75955|reactome:R-SPO-9018519|refseq:NP_596149.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|mint:O74627|interpro:IPR036915|interpro:IPR043198	refseq:NP_595629.1|reactome:R-SPO-176187|ensemblfungi:SPBC11B10.09(gene)|ensemblfungi:SPBC11B10.09.1(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0062123"(regulation of linear element maturation)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0072435"(response to mitotic G2 DNA damage checkpoint signaling)|go:"GO:0072441"(response to meiotic DNA replication checkpoint signaling)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0110045"(negative regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902424"(negative regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902845"(negative regulation of mitotic spindle elongation)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903380"(positive regulation of mitotic chromosome condensation)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1903467"(negative regulation of mitotic DNA replication initiation)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)|go:"GO:1904537"(negative regulation of mitotic telomere tethering at nuclear periphery)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905263"(positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:1905757"(negative regulation of primary cell septum biogenesis)|go:"GO:1905785"(negative regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990820"(response to mitotic DNA integrity checkpoint signaling)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-1076N|reactome:R-SPO-68962|reactome:R-SPO-69017|reactome:R-SPO-69202|reactome:R-SPO-68949|reactome:R-SPO-69656	-	-	-	figure legend:Figure 3.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/11/03	2014/10/16	rogid:UmeTCbwP2A4WzIPgA2vRJAzBIi0284812	rogid:Xm26f9FnmjG9I6P1hrk/9kWszzY284812	intact-crc:1829C09386240757|rigid:T6bbMauxPg2Jtxr+b5AnTDCGJt0	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)