#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-2107797 uniprotkb:P06742 flybase:FBgn0040638 intact:EBI-278491|uniprotkb:Q27381|uniprotkb:Q27414|uniprotkb:Q94988|uniprotkb:Q9VB12|uniprotkb:P06743|uniprotkb:P92155|uniprotkb:P92156|uniprotkb:P92157|uniprotkb:P92183|uniprotkb:P92187|uniprotkb:P92196|uniprotkb:Q24380|uniprotkb:Q24381|uniprotkb:Q24382|uniprotkb:Q24383|uniprotkb:Q27304|uniprotkb:Q27315|ensemblmetazoa:FBpp0084566|ensemblmetazoa:FBpp0310544 psi-mi:cg12979-drome_protei(display_short)|psi-mi:EBI-2107797(display_long) psi-mi:mlc1_drome(display_long)|uniprotkb:Mlc1(gene name)|psi-mi:Mlc1(display_short)|uniprotkb:MLC-ALK(gene name synonym)|uniprotkb:CG5596(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2107786|imex:IM-9552-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_476639.1|refseq:NP_476640.1|flybase:FBgn0002772|refseq:NP_001287569.1|dip:DIP-23903N|ensemblmetazoa:FBgn0002772(gene)|ensemblmetazoa:FBtr0085196(transcript)|ensemblmetazoa:FBtr0344131(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007498"(mesoderm development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR029655|rcsb pdb:5W1A|reactome:R-DME-5627123 psi-mi:"MI:0469"(intact) no-uniprot-update:An amino acid sequence which is not represented in UniProt - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 - rogid:6S6X8V4CbYNg/YcIGaePCHd87kA7227 intact-crc:5FBF2CBE1543F208 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q961W1 uniprotkb:Q9W058 intact:EBI-2108274|ensemblmetazoa:FBpp0077884 intact:EBI-184518|intact:EBI-2108267|uniprotkb:Q8IRG3|ensemblmetazoa:FBpp0072723 psi-mi:q961w1_drome(display_long)|uniprotkb:Hpd(gene name)|psi-mi:Hpd(display_short)|uniprotkb:Dmel\CG11796(gene name synonym)|uniprotkb:CG11796(orf name)|uniprotkb:Dmel_CG11796(orf name) psi-mi:scot_drome(display_long)|uniprotkb:SCOT(gene name)|psi-mi:SCOT(display_short)|uniprotkb:3-oxoacid CoA-transferase(gene name synonym)|uniprotkb:CG1140(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108271|imex:IM-9552-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649225.1|flybase:FBgn0036992|ensemblmetazoa:FBgn0036992(gene)|ensemblmetazoa:FBtr0078226(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003868"(4-hydroxyphenylpyruvate dioxygenase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR004360(Glyoxalase/bleomycin resistance protein/dioxygenase)|interpro:IPR005956(4-hydroxyphenylpyruvate dioxygenase)|interpro:IPR029068|interpro:IPR037523|interpro:IPR041735|interpro:IPR041736 flybase:FBgn0035298|refseq:NP_728699.1|refseq:NP_647683.1|ensemblmetazoa:FBgn0035298(gene)|ensemblmetazoa:FBtr0072844(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|rcsb pdb:4KGB|reactome:R-DME-77108 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2017/01/20 rogid:YKh59nE82P+UI1HZZA8dsZpTBok7227 rogid:bIJj7kneX3iLtv9AMq4Myy5KeWc7227 intact-crc:4752AF56C7AC4A81|rigid:dVfLfgDMZZSS/t2RHf3yC+CSqiY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTE0 uniprotkb:A1Z9S1 intact:EBI-87041|ensemblmetazoa:FBpp0075932 intact:EBI-2108282|ensemblmetazoa:FBpp0290948 psi-mi:bl1s2_drome(display_long)|uniprotkb:Blos2(gene name)|psi-mi:Blos2(display_short)|uniprotkb:CG14145(orf name) psi-mi:bl1s1_drome(display_long)|uniprotkb:Blos1(gene name)|psi-mi:Blos1(display_short)|uniprotkb:CG30077(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108279|imex:IM-9552-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0036118(gene)|ensemblmetazoa:FBtr0076202(transcript)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032418"(lysosome localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0099078"(BORC complex)|interpro:IPR019269|refseq:NP_648427.1|flybase:FBgn0036118 refseq:NP_725401.2|flybase:FBgn0050077|ensemblmetazoa:FBgn0050077(gene)|ensemblmetazoa:FBtr0301734(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008057"(eye pigment granule organization)|go:"GO:0008355"(olfactory learning)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0050808"(synapse organization)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0098793"(presynapse)|interpro:IPR009395(GCN5-like 1)|reactome:R-DME-432720 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:bTHARl+MiwEUHncl2vsedXacjh47227 rogid:xhDun/EPEKSM4F5ENil931AWjPo7227 intact-crc:13B19086A1199DC7|rigid:F5F8OSzyr5DfTnq+yxu4E0vv8e0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P22769 uniprotkb:Q9XYN7 intact:EBI-93148|uniprotkb:Q9VXI9|ensemblmetazoa:FBpp0073989 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psa71_drome(display_long)|uniprotkb:Prosalpha4(gene name)|psi-mi:Prosalpha4(display_short)|uniprotkb:PROS-28.1(gene name synonym)|uniprotkb:PROS-Dm28.1(gene name synonym)|uniprotkb:Pros28.1(gene name synonym)|uniprotkb:Proteasome 28 kDa subunit 1(gene name synonym)|uniprotkb:CG3422(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108287|imex:IM-9552-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525092.1|flybase:FBgn0004066|ensemblmetazoa:FBgn0004066(gene)|ensemblmetazoa:FBtr0074210(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-69601|reactome:R-DME-69017|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-450408|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-4608870|reactome:R-DME-432395|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|dip:DIP-17376N refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:gQpRF01CDAsvV4Rc2YSFf8drjtY7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:77AFC174E044EA04|rigid:H37yb+rzbg9vHBGxnG4R2VVzUzg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K148 uniprotkb:P22769 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 intact:EBI-93148|uniprotkb:Q9VXI9|ensemblmetazoa:FBpp0073989 psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:psa71_drome(display_long)|uniprotkb:Prosalpha4(gene name)|psi-mi:Prosalpha4(display_short)|uniprotkb:PROS-28.1(gene name synonym)|uniprotkb:PROS-Dm28.1(gene name synonym)|uniprotkb:Pros28.1(gene name synonym)|uniprotkb:Proteasome 28 kDa subunit 1(gene name synonym)|uniprotkb:CG3422(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108292|imex:IM-9552-450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 refseq:NP_525092.1|flybase:FBgn0004066|ensemblmetazoa:FBgn0004066(gene)|ensemblmetazoa:FBtr0074210(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-69601|reactome:R-DME-69017|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-450408|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-4608870|reactome:R-DME-432395|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|dip:DIP-17376N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 rogid:gQpRF01CDAsvV4Rc2YSFf8drjtY7227 intact-crc:5EF40CAA3B461B88|rigid:KjRYMjpsNqcrwxhFXLXxTMPd6/c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P25160 uniprotkb:P22769 intact:EBI-126648|uniprotkb:Q9VUW7|ensemblmetazoa:FBpp0075272 intact:EBI-93148|uniprotkb:Q9VXI9|ensemblmetazoa:FBpp0073989 psi-mi:arl1_drome(display_long)|uniprotkb:Arl1(gene name)|psi-mi:Arl1(display_short)|uniprotkb:Arf72A(gene name synonym)|uniprotkb:arl(gene name synonym)|uniprotkb:CG6025(orf name) psi-mi:psa71_drome(display_long)|uniprotkb:Prosalpha4(gene name)|psi-mi:Prosalpha4(display_short)|uniprotkb:PROS-28.1(gene name synonym)|uniprotkb:PROS-Dm28.1(gene name synonym)|uniprotkb:Pros28.1(gene name synonym)|uniprotkb:Proteasome 28 kDa subunit 1(gene name synonym)|uniprotkb:CG3422(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108301|imex:IM-9552-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524098.2|flybase:FBgn0000115|ensemblmetazoa:FBgn0000115(gene)|ensemblmetazoa:FBtr0075517(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007431"(salivary gland development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0033227"(dsRNA transport)|go:"GO:0033363"(secretory granule organization)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0035220"(wing disc development)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070861"(regulation of protein exit from endoplasmic reticulum)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:0098793"(presynapse)|go:"GO:1903292"(protein localization to Golgi membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-DME-6811440|dip:DIP-21617N refseq:NP_525092.1|flybase:FBgn0004066|ensemblmetazoa:FBgn0004066(gene)|ensemblmetazoa:FBtr0074210(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-69601|reactome:R-DME-69017|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-450408|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-4608870|reactome:R-DME-432395|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|dip:DIP-17376N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jqANfQVuQo74OlKdz2MiJ4rAU4A7227 rogid:gQpRF01CDAsvV4Rc2YSFf8drjtY7227 intact-crc:AB663B416F41512D|rigid:i+uKk9GkFWTLKVHcPkf6boZzJu0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VSF3 uniprotkb:Q9VJ33 intact:EBI-96764|ensemblmetazoa:FBpp0076445|ensemblmetazoa:FBpp0304448|ensemblmetazoa:FBpp0304449 intact:EBI-90023|uniprotkb:Q29QE5|ensemblmetazoa:FBpp0080733|ensemblmetazoa:FBpp0309711 psi-mi:ubc2m_drome(display_long)|uniprotkb:UbcE2M(gene name)|psi-mi:UbcE2M(display_short)|uniprotkb:Nedd8 carrier protein(gene name synonym)|uniprotkb:Ubc12(gene name synonym)|uniprotkb:CG7375(orf name) psi-mi:nedd8_drome(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:CG10679(orf name)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108306|imex:IM-9552-448 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648187.1|flybase:FBgn0035853|refseq:NP_001261567.1|refseq:NP_001261568.1|ensemblmetazoa:FBgn0035853(gene)|ensemblmetazoa:FBtr0076722(transcript)|ensemblmetazoa:FBtr0332138(transcript)|ensemblmetazoa:FBtr0332139(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-8951664|reactome:R-DME-983168 refseq:NP_609919.1|flybase:FBgn0032725|ensemblmetazoa:FBgn0032725(gene)|ensemblmetazoa:FBtr0081192(transcript)|ensemblmetazoa:FBtr0342928(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030431"(sleep)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-DME-5689603|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-917937|refseq:NP_001286070.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:8BmWwPgdHLh8OwzeQIVFR0ZOAGs7227 rogid:3P7TFMLheJ3IKTDNacGZdCxjrVc7227 intact-crc:436FB49D8EA9C8B6|rigid:dr6JpyCQKYQ8eBNMQ17/lxkoEv8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VSF3 uniprotkb:Q9VUR4 intact:EBI-96764|ensemblmetazoa:FBpp0076445|ensemblmetazoa:FBpp0304448|ensemblmetazoa:FBpp0304449 intact:EBI-2108311|uniprotkb:D0IQC8|uniprotkb:Q8IQM4|ensemblmetazoa:FBpp0289558|ensemblmetazoa:FBpp0290404 psi-mi:ubc2m_drome(display_long)|uniprotkb:UbcE2M(gene name)|psi-mi:UbcE2M(display_short)|uniprotkb:Nedd8 carrier protein(gene name synonym)|uniprotkb:Ubc12(gene name synonym)|uniprotkb:CG7375(orf name) psi-mi:q9vur4_drome(display_long)|uniprotkb:Dmel\CG7656(gene name)|psi-mi:Dmel\CG7656(display_short)|uniprotkb:CG7656-RA(gene name synonym)|uniprotkb:CG7656(orf name)|uniprotkb:Dmel_CG7656(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108314|imex:IM-9552-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648187.1|flybase:FBgn0035853|refseq:NP_001261567.1|refseq:NP_001261568.1|ensemblmetazoa:FBgn0035853(gene)|ensemblmetazoa:FBtr0076722(transcript)|ensemblmetazoa:FBtr0332138(transcript)|ensemblmetazoa:FBtr0332139(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0061654"(NEDD8 conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-8951664|reactome:R-DME-983168 refseq:NP_648783.4|refseq:NP_730058.2|flybase:FBgn0036516|ensemblmetazoa:FBgn0036516(gene)|ensemblmetazoa:FBtr0300329(transcript)|ensemblmetazoa:FBtr0301186(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-8866652|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:8BmWwPgdHLh8OwzeQIVFR0ZOAGs7227 rogid:coGA0MXK+GugXCL/79B7bYwsKwM7227 intact-crc:3A44C9E6ABD5B428|rigid:QOx2ex3huReRVk8tsZiGElvn8sU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:O18413 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108319|imex:IM-9552-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:7C90523929FDBBC4|rigid:Kb9CFuqwQxE0lWIeJntlZrnVUCk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VPY9 uniprotkb:Q9VEV3 intact:EBI-168505|ensemblmetazoa:FBpp0077637|ensemblmetazoa:FBpp0297899|ensemblmetazoa:FBpp0307363 intact:EBI-189213|ensemblmetazoa:FBpp0082765|ensemblmetazoa:FBpp0307945 psi-mi:q9vpy9_drome(display_long)|uniprotkb:Dmel\CG5001(gene name)|psi-mi:Dmel\CG5001(display_short)|uniprotkb:CG5001-RA(gene name synonym)|uniprotkb:CG5001(orf name)|uniprotkb:Dmel_CG5001(orf name) psi-mi:q9vev3_drome(display_long)|uniprotkb:Dmel\CG14894(gene name)|psi-mi:Dmel\CG14894(display_short)|uniprotkb:CG14894(orf name)|uniprotkb:Dmel_CG14894(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108324|imex:IM-9552-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245832.1|refseq:NP_608586.2|flybase:FBgn0031322|refseq:NP_001259861.1|ensemblmetazoa:FBgn0031322(gene)|ensemblmetazoa:FBtr0077972(transcript)|ensemblmetazoa:FBtr0307056(transcript)|ensemblmetazoa:FBtr0335379(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869 refseq:NP_650543.1|flybase:FBgn0038428|refseq:NP_001262636.1|ensemblmetazoa:FBgn0038428(gene)|ensemblmetazoa:FBtr0083314(transcript)|ensemblmetazoa:FBtr0337016(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0071806"(protein transmembrane transport)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:urnTyA7Sh6KGQWSKg2AEENE13M07227 rogid:2XS2RA2lEWu3bTEoShb8ITH4Pdo7227 intact-crc:4CDBB4A3C5C62B1B|rigid:gvEUrdhViRgpN2J0sOWMm4sIIT0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K1Q7 uniprotkb:Q9VAQ5 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 intact:EBI-2108336|ensemblmetazoa:FBpp0084729 psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:dim1_drome(display_long)|uniprotkb:Probable 18S rRNA dimethylase(gene name synonym)|uniprotkb:"Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase"(gene name synonym)|uniprotkb:CG11837(orf name)|uniprotkb:"Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108333|imex:IM-9552-452 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 refseq:NP_651660.1|flybase:FBgn0039627|ensemblmetazoa:FBgn0039627(gene)|ensemblmetazoa:FBtr0085360(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031167"(rRNA methylation)|go:"GO:0052909"("18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity")|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 rogid:lEirLFLDo2UKOqNTwlxLIfpyGQk7227 intact-crc:F30689AA2491E310|rigid:3zExxkHzDIqF4iM2i1d4duLBttM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P51406 uniprotkb:Q9VAQ5 intact:EBI-117198|uniprotkb:Q9W3N3|ensemblmetazoa:FBpp0071046 intact:EBI-2108336|ensemblmetazoa:FBpp0084729 psi-mi:bys_drome(display_long)|uniprotkb:bys(gene name)|psi-mi:bys(display_short)|uniprotkb:CG1430(orf name)|uniprotkb:Protein bys(gene name synonym) psi-mi:dim1_drome(display_long)|uniprotkb:Probable 18S rRNA dimethylase(gene name synonym)|uniprotkb:"Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase"(gene name synonym)|uniprotkb:CG11837(orf name)|uniprotkb:"Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108341|imex:IM-9552-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511074.1|flybase:FBgn0010292|ensemblmetazoa:FBgn0010292(gene)|ensemblmetazoa:FBtr0071090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR007955(Bystin)|dip:DIP-19855N refseq:NP_651660.1|flybase:FBgn0039627|ensemblmetazoa:FBgn0039627(gene)|ensemblmetazoa:FBtr0085360(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031167"(rRNA methylation)|go:"GO:0052909"("18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity")|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+a0Azeyc1t5adGw9xM6QwZiMevI7227 rogid:lEirLFLDo2UKOqNTwlxLIfpyGQk7227 intact-crc:A16D2422336D3B80|rigid:rUUtJPC6SjGlzrcacSSaGS/LIsk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P36188-1 uniprotkb:Q7JX82 intact:EBI-251850|ensemblmetazoa:FBpp0074298 intact:EBI-128171|intact:EBI-2108346|ensemblmetazoa:FBpp0087887|ensemblmetazoa:FBpp0087888|ensemblmetazoa:FBpp0087889|ensemblmetazoa:FBpp0087890|ensemblmetazoa:FBpp0308405 psi-mi:p36188-1(display_long)|uniprotkb:G(isoform synonym)|uniprotkb:wupA(gene name)|psi-mi:wupA(display_short)|uniprotkb:HDP(gene name synonym)|uniprotkb:TnI(gene name synonym)|uniprotkb:Protein heldup(gene name synonym)|uniprotkb:Protein wings apart-A(gene name synonym)|uniprotkb:CG7178(orf name) psi-mi:q7jx82_drome(display_long)|uniprotkb:kermit(gene name)|psi-mi:kermit(display_short)|uniprotkb:Dmel_CG11546(orf name)|uniprotkb:"l(2)02045"(gene name synonym)|uniprotkb:CG11546(orf name)|uniprotkb:"BEST:LD04728"(gene name synonym)|uniprotkb:Dmel\CG11546(gene name synonym)|uniprotkb:LD04728(gene name synonym)|uniprotkb:dGIPC(gene name synonym)|uniprotkb:dKermit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108350|imex:IM-9552-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-251833(tnni_drome)|ensemblmetazoa:FBgn0283471(gene)|ensemblmetazoa:FBtr0074524(transcript) refseq:NP_652028.1|refseq:NP_724649.1|refseq:NP_724650.1|refseq:NP_724651.1|flybase:FBgn0010504|refseq:NP_001286187.1|ensemblmetazoa:FBgn0010504(gene)|ensemblmetazoa:FBtr0088811(transcript)|ensemblmetazoa:FBtr0088812(transcript)|ensemblmetazoa:FBtr0088813(transcript)|ensemblmetazoa:FBtr0088814(transcript)|ensemblmetazoa:FBtr0339296(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0008045"(motor neuron axon guidance)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Ewyc6AfWJ/D3fa3cyiavnZYDahg7227 rogid:uHavJlpeMXrae/mcB2vtCau8tjI7227 intact-crc:6F601A571906FA51|rigid:CuDx7YU/XWbusMm69maLg70w4Ms false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XZ16 uniprotkb:Q9VW54 intact:EBI-192808|ensemblmetazoa:FBpp0083740 intact:EBI-164211|uniprotkb:Q9XZ26|ensemblmetazoa:FBpp0074662 psi-mi:q9xz16_drome(display_long)|uniprotkb:4972728(gene name synonym)|uniprotkb:"BcDNA:LD21504"(gene name synonym)|uniprotkb:DmUBLCP1(gene name synonym)|uniprotkb:Dmel\CG6697(gene name synonym)|uniprotkb:UBLCP1(gene name synonym)|uniprotkb:Ublcp1(gene name)|psi-mi:Ublcp1(display_short)|uniprotkb:Ubiquitin-like domain-containing CTD phosphatase 1(gene name synonym)|uniprotkb:CG6697(orf name)|uniprotkb:Dmel_CG6697(orf name) psi-mi:q9vw54_drome(display_long)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)|uniprotkb:"BcDNA:LD21723"(gene name synonym)|uniprotkb:Dmel\CG7762(gene name synonym)|uniprotkb:RPN1(gene name synonym)|uniprotkb:S2(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Dmel_CG7762(orf name)|uniprotkb:CG7762(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108355|imex:IM-9552-454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651118.1|flybase:FBgn0027526|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000626(Ubiquitin)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011943(HAD-superfamily hydrolase, subfamily IIID)|interpro:IPR023214|interpro:IPR029071|interpro:IPR036412|rcsb pdb:3SHQ|ensemblmetazoa:FBgn0027526(gene)|ensemblmetazoa:FBtr0084347(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus) refseq:NP_649158.1|flybase:FBgn0028695|interpro:IPR041433|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR040892|reactome:R-DME-382556|ensemblmetazoa:FBgn0028695(gene)|ensemblmetazoa:FBtr0074893(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:IrDUxC5FdrcvcMohfEhsUkIKRH07227 rogid:34XY3/zZaoyJH4owwclaQ98dE+s7227 intact-crc:5296090CED5FF116|rigid:sjWyvAyr1pcH4ONfYdMAjNx+8v8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q86B87-1 uniprotkb:Q08605-1 intact:EBI-1433422|ensemblmetazoa:FBpp0083478 intact:EBI-665797 psi-mi:q86b87-1(display_long)|uniprotkb:"mod(mdg4)"(gene name)|psi-mi:"mod(mdg4)"(display_short)|uniprotkb:bpd(gene name synonym)|uniprotkb:doom(gene name synonym)|uniprotkb:"E(var)3-93D"(gene name synonym)|uniprotkb:CG32491(orf name)|uniprotkb:67.2(isoform synonym)|uniprotkb:"E(VAR)3-93D"(isoform synonym) psi-mi:q08605-1(display_long)|uniprotkb:F(isoform synonym)|uniprotkb:GAGA-581(isoform synonym)|uniprotkb:Trl(gene name)|psi-mi:Trl(display_short)|uniprotkb:Adf-2(gene name synonym)|uniprotkb:GAGA(gene name synonym)|uniprotkb:Nc70F(gene name synonym)|uniprotkb:TFGAGA(gene name synonym)|uniprotkb:Adh transcription factor 2(gene name synonym)|uniprotkb:GAGA factor(gene name synonym)|uniprotkb:Neural conserved at 70F(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:CG33261(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108360|imex:IM-9552-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-124784(isoform-parent)|ensemblmetazoa:FBgn0002781(gene)|ensemblmetazoa:FBtr0084079(transcript) intact:EBI-300317(gaga_drome) psi-mi:"MI:0469"(intact) isoform-comment:C-terminal exons are translated from the opposite DNA strand. This may be due to a trans-splicing event. - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:b2OX/raroy6BMkaSC4EuYYprayM7227 rogid:s2lpiYJCLr9x3aKiQRvlG3gE9nk7227 intact-crc:AF81CA5BFE80D4EB|rigid:0h2fuIuDflGaMA8r38cgOMueDBY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXL4 uniprotkb:Q9I7X6 intact:EBI-95724|intact:EBI-1628917|ensemblmetazoa:FBpp0073937|ensemblmetazoa:FBpp0309613 intact:EBI-216406|uniprotkb:Q9W540|uniprotkb:Q7KW04|uniprotkb:O46078|intact:EBI-216413|ensemblmetazoa:FBpp0070306 psi-mi:q9vxl4_drome(display_long)|uniprotkb:Rrp47(gene name)|psi-mi:Rrp47(display_short)|uniprotkb:CG8928-RA(gene name synonym)|uniprotkb:Dmel\CG8928(gene name synonym)|uniprotkb:dRrp47(gene name synonym)|uniprotkb:lincRNA.1007(gene name synonym)|uniprotkb:Dmel_CG8928(orf name)|uniprotkb:CG8928(orf name) psi-mi:carme_drome(display_long)|uniprotkb:CG11596(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108365|imex:IM-9552-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573092.1|flybase:FBgn0030711|refseq:NP_001285310.1|ensemblmetazoa:FBgn0030711(gene)|ensemblmetazoa:FBtr0074132(transcript)|ensemblmetazoa:FBtr0342745(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|reactome:R-DME-6791226 refseq:NP_569963.1|refseq:NP_726779.1|refseq:NP_726780.1|flybase:FBgn0023522|refseq:NP_001259154.1|refseq:NP_001259155.1|ensemblmetazoa:FBgn0023522(gene)|ensemblmetazoa:FBtr0070319(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0030735"(carnosine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0035498"(carnosine metabolic process)|interpro:IPR012901(N2227-like)|interpro:IPR029063|reactome:R-DME-70921 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Sc3MNHqhfXFSlTGyNy22FKHt587227 rogid:GUnznZeecSwEkg/MC0QDM+N9cP47227 intact-crc:A7683B32B3DDBAEC|rigid:88B8YKOZLE+sGO2MSq3gsAv/dlU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O17311 uniprotkb:Q9XYN7 intact:EBI-2108373 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:o17311_drome(display_long)|uniprotkb:beta2_dm(gene name synonym)|uniprotkb:CG3329(orf name)|uniprotkb:Pros-beta-2(gene name synonym)|uniprotkb:Prosbeta2(gene name)|psi-mi:Prosbeta2(display_short) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108370|imex:IM-9552-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023174|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:kKcHoGOVnpj4GwJCUwhH8LJFS4U7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:A28B5C1B5BBC1612|rigid:jCgfeQUOyJbB2fAW8xIGypXxVnM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:O17311 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-2108373 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:o17311_drome(display_long)|uniprotkb:beta2_dm(gene name synonym)|uniprotkb:CG3329(orf name)|uniprotkb:Pros-beta-2(gene name synonym)|uniprotkb:Prosbeta2(gene name)|psi-mi:Prosbeta2(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108380|imex:IM-9552-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N flybase:FBgn0023174|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:kKcHoGOVnpj4GwJCUwhH8LJFS4U7227 intact-crc:4E6A51FE39B814CE|rigid:GsIqdWqjfRn1Imb+BrJ9TH9AK6Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJ39 uniprotkb:O96794 intact:EBI-142535|uniprotkb:Q961A0|intact:EBI-3428985|uniprotkb:R4GRV7|intact:EBI-2108385|uniprotkb:Q7KT44|ensemblmetazoa:FBpp0312552 intact:EBI-2108391 psi-mi:q9vj39_drome(display_long)|uniprotkb:pepCG10602(gene name)|psi-mi:pepCG10602(display_short)|uniprotkb:Dmel\CG10602(gene name synonym)|uniprotkb:MRPL13(gene name synonym)|uniprotkb:mRpL13(gene name synonym)|uniprotkb:CG10602(orf name)|uniprotkb:Dmel_CG10602(orf name) psi-mi:o96794_drome(display_long)|uniprotkb:Daminopep-p(gene name synonym)|uniprotkb:ApepP(gene name)|psi-mi:ApepP(display_short)|uniprotkb:CG6291(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108388|imex:IM-9552-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0032721|refseq:NP_609916.5|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0004463"(leukotriene-A4 hydrolase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0043171"(peptide catabolic process)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR036899|interpro:IPR038502|interpro:IPR042097|reactome:R-DME-2142691|reactome:R-DME-6798695|reactome:R-DME-9018676|reactome:R-DME-9018681|reactome:R-DME-9018896|reactome:R-DME-9020265|reactome:R-DME-9023661|ensemblmetazoa:FBgn0032721(gene)|ensemblmetazoa:FBtr0347402(transcript) flybase:FBgn0026150|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR000587(Creatinase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR029149|interpro:IPR032416|interpro:IPR033740|interpro:IPR036005 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2016/03/15 rogid:lY/LNk0Uowd7gJX5U2DcKbEdfbQ7227 rogid:v0cFpC+s9qA6wE1X8tFRAgthzPc7227 intact-crc:9F0CD137207C0159|rigid:FugsUZkAiR8flR/1bLrkALKC4qk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K1Y4 uniprotkb:Q9VTC4 intact:EBI-175932|intact:EBI-2108398|ensemblmetazoa:FBpp0086590 intact:EBI-100085|ensemblmetazoa:FBpp0075999 psi-mi:ciao1_drome(display_long)|uniprotkb:CG12797(orf name)|uniprotkb:Ciao1(gene name)|psi-mi:Ciao1(display_short) psi-mi:gall2_drome(display_long)|uniprotkb:galla-2(gene name)|psi-mi:galla-2(display_short)|uniprotkb:CG7949(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108403|imex:IM-9552-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610996.1|flybase:FBgn0033972|ensemblmetazoa:FBgn0033972(gene)|ensemblmetazoa:FBtr0087460(transcript)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0097361"(CIA complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR028608|interpro:IPR036322|rcsb pdb:6TBL|rcsb pdb:6TBN|rcsb pdb:6TC0 refseq:NP_648416.1|flybase:FBgn0036107|ensemblmetazoa:FBgn0036107(gene)|ensemblmetazoa:FBtr0076270(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051301"(cell division)|go:"GO:0097361"(CIA complex)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|rcsb pdb:6TBL|rcsb pdb:6TBN|rcsb pdb:6TC0|dip:DIP-20907N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Phz26cdXUQJhXLmnG7x/rOotC8U7227 rogid:aXgg47iVuWLi01lFZYcp4hRJLak7227 intact-crc:1820BA7114992258|rigid:TyuJvJcck69oC94G0e/d3mnj5gQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) intact:EBI-2108411 uniprotkb:P48609 - intact:EBI-94216|intact:EBI-1627775|uniprotkb:Q94878|uniprotkb:Q9V7D8|ensemblmetazoa:FBpp0086483 psi-mi:q8img7_drome(display_short)|psi-mi:EBI-2108411(display_long)|uniprotkb:Dmel_CG11525(orf name)|uniprotkb:CycG(gene name)|psi-mi:CycG(display_short)|uniprotkb:CG11525(orf name) psi-mi:cdk5_drome(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:CG8203(orf name)|uniprotkb:Cell division protein kinase 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108408|imex:IM-9552-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IMG7(uniprot-removed-ac) refseq:NP_477080.1|flybase:FBgn0013762|go:"GO:0106310"(protein serine kinase activity)|ensemblmetazoa:FBgn0013762(gene)|ensemblmetazoa:FBtr0087350(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007629"(flight behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051642"(centrosome localization)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-399956|reactome:R-DME-6804756|go:"GO:0106311"|dip:DIP-22131N psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GwDM/XQ/mtqkftw2t9BwmojZmFA7227 rogid:VNwgPo7AEv+BIJY9ncTvrZA2jQI7227 intact-crc:4A497BE3E26CA681|rigid:r+jPst8S//e2JU3Jjwt+Van/LJc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77263 uniprotkb:Q9VR56 intact:EBI-103749|uniprotkb:Q9W527|ensemblmetazoa:FBpp0070317 intact:EBI-2108417|ensemblmetazoa:FBpp0077043 psi-mi:trmb_drome(display_long)|uniprotkb:"tRNA (guanine(46)-N(7))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA(m7G46)-methyltransferase"(gene name synonym)|uniprotkb:CG4045(orf name) psi-mi:tm10a_drome(display_long)|uniprotkb:trmt10a(gene name)|psi-mi:trmt10a(display_short)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 2 homolog"(gene name synonym)|uniprotkb:CG14618(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108420|imex:IM-9552-456 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569978.1|flybase:FBgn0025629|ensemblmetazoa:FBgn0025629(gene)|ensemblmetazoa:FBtr0070331(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008176"("tRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0036265"("RNA (guanine-N7)-methylation")|go:"GO:0043527"(tRNA methyltransferase complex)|interpro:IPR003358(Putative methyltransferase)|interpro:IPR025763|interpro:IPR029063|dip:DIP-18791N refseq:NP_608464.1|flybase:FBgn0031189|ensemblmetazoa:FBgn0031189(gene)|ensemblmetazoa:FBtr0077351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0090646"(mitochondrial tRNA processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR016653("tRNA (guanine-N(1)-)-methyltransferase, metazoa")|interpro:IPR028564|interpro:IPR038459 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:iWhRQhfcIRwzaRGa4qiDv2Ziqzc7227 rogid:aR0eQxo5M3ptChadlxLOZveDb+s7227 intact-crc:A2F71EF55CBAB5A3|rigid:lHzD4rCTfPZ6PvL3ZrG/d2mfEBk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNF4 uniprotkb:Q7K2Y9 intact:EBI-107760|ensemblmetazoa:FBpp0078386 intact:EBI-157455|ensemblmetazoa:FBpp0086423|ensemblmetazoa:FBpp0300971|ensemblmetazoa:FBpp0300972|ensemblmetazoa:FBpp0309027|intact:EBI-2108428 psi-mi:q9vnf4_drome(display_long)|uniprotkb:Dmel\CG31546(gene name)|psi-mi:Dmel\CG31546(display_short)|uniprotkb:CG2907(gene name synonym)|uniprotkb:anon-WO0140519.189(gene name synonym)|uniprotkb:CG31546(orf name)|uniprotkb:Dmel_CG31546(orf name) psi-mi:ntaq1_drome(display_long)|uniprotkb:CG8253(orf name)|uniprotkb:tun(gene name)|psi-mi:tun(display_short)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:Protein tungus(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108425|imex:IM-9552-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730973.1|flybase:FBgn0051546|ensemblmetazoa:FBgn0051546(gene)|ensemblmetazoa:FBtr0078737(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 ensemblmetazoa:FBgn0034046(gene)|ensemblmetazoa:FBtr0087287(transcript)|ensemblmetazoa:FBtr0308814(transcript)|ensemblmetazoa:FBtr0308815(transcript)|ensemblmetazoa:FBtr0340013(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|refseq:NP_001246351.1|refseq:NP_001246352.1|refseq:NP_001286468.1|refseq:NP_611061.1|flybase:FBgn0034046 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIM9UzuNBl64OYwk4nZ4JntGmPQ7227 rogid:Est0CQKXm6fJTkv4cQGY2sCCpa87227 intact-crc:73A7C375651E7F7F|rigid:AVLjU6pUm6IY6mrBMSGawQEwMmQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VYD6 uniprotkb:Q9VV76 intact:EBI-2108447|ensemblmetazoa:FBpp0073607|ensemblmetazoa:FBpp0309558 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 psi-mi:q9vyd6_drome(display_long)|uniprotkb:CG1662(orf name)|uniprotkb:Dmel_CG1662(orf name)|uniprotkb:Dmel\CG1662(gene name)|psi-mi:Dmel\CG1662(display_short) psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108451|imex:IM-9552-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572883.1|flybase:FBgn0030481|refseq:NP_001285209.1|ensemblmetazoa:FBgn0030481(gene)|ensemblmetazoa:FBtr0073776(transcript)|ensemblmetazoa:FBtr0342624(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061668"(mitochondrial ribosome assembly)|interpro:IPR007248(Mpv17/PMP22) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:qKrx47SJnFnOTJly32jMF4cWGKA7227 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 intact-crc:D3EF26A604EA725E|rigid:WNgFyMJPO5NTQpYM74Ji+7B8Yiw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VB62 uniprotkb:A1ZBR5 intact:EBI-140909|uniprotkb:Q95S59|uniprotkb:Q9TXB0|ensemblmetazoa:FBpp0113035 intact:EBI-196335|intact:EBI-2108438|uniprotkb:Q8T8U2|ensemblmetazoa:FBpp0085632 psi-mi:dpoa2_drome(display_long)|uniprotkb:PolA2(gene name)|psi-mi:PolA2(display_short)|uniprotkb:DNA polymerase alpha 73 kDa subunit(gene name synonym)|uniprotkb:DNApol-alpha73(gene name synonym)|uniprotkb:CG5923(orf name) psi-mi:aktp2_drome(display_long)|uniprotkb:CG16894(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108435|imex:IM-9552-458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_733206.3|flybase:FBgn0005696|ensemblmetazoa:FBgn0005696(gene)|ensemblmetazoa:FBtr0114543(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-DME-113501|reactome:R-DME-68952|reactome:R-DME-68962|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183 refseq:NP_611455.1|flybase:FBgn0034483|ensemblmetazoa:FBgn0034483(gene)|ensemblmetazoa:FBtr0086324(transcript)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:IGQYdCQgAGfKg6D2HZ52xpHkHCs7227 rogid:UsjH/vA9KKL8Klu8zeBF6DNqBFE7227 intact-crc:AECE4BA911BB1A02|rigid:eR9CXiT93rpUI/hohqKNxfsTuBg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P49905-1 uniprotkb:Q27272 intact:EBI-1010511|ensemblmetazoa:FBpp0081918|ensemblmetazoa:FBpp0081916 intact:EBI-174260|uniprotkb:Q95RJ4|uniprotkb:Q9VX16|ensemblmetazoa:FBpp0074237 psi-mi:p49905-1(display_long)|uniprotkb:Taf12(gene name)|psi-mi:Taf12(display_short)|uniprotkb:p28-alpha/p22(gene name synonym)|uniprotkb:TAF30-ALPHA(gene name synonym)|uniprotkb:TAFII30 alpha(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 28-alpha kDa/22 kDa subunits(gene name synonym)|uniprotkb:CG17358(orf name)|uniprotkb:A(isoform synonym)|uniprotkb:B(isoform synonym) psi-mi:taf9_drome(display_long)|uniprotkb:"e(y)1"(gene name)|psi-mi:"e(y)1"(display_short)|uniprotkb:TAF40(gene name synonym)|uniprotkb:CG6474(orf name)|uniprotkb:Transcription initiation factor TFIID 42 kDa subunit(gene name synonym)|uniprotkb:TAFII40(gene name synonym)|uniprotkb:p42(gene name synonym)|uniprotkb:Protein enhancer of yellow 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108456|imex:IM-9552-460 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-115002(taf12_drome)|ensemblmetazoa:FBtr0082440(transcript)|ensemblmetazoa:FBtr0082442(transcript)|ensemblmetazoa:FBgn0011290(gene) refseq:NP_523391.3|flybase:FBgn0000617|dip:DIP-239N|ensemblmetazoa:FBgn0000617(gene)|ensemblmetazoa:FBtr0074463(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|rcsb pdb:1TAF|reactome:R-DME-5689880|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WmJM0JQtNVHg0shzMoeQRK6MoWA7227 rogid:MB1JQfTIG1nLfK/apoLrr6GHKNU7227 intact-crc:34BCC87AE8D1645A|rigid:malj/HbuNiLTkiNG2Ks0AdttgBo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q9VUR4 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-2108311|uniprotkb:D0IQC8|uniprotkb:Q8IQM4|ensemblmetazoa:FBpp0289558|ensemblmetazoa:FBpp0290404 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q9vur4_drome(display_long)|uniprotkb:Dmel\CG7656(gene name)|psi-mi:Dmel\CG7656(display_short)|uniprotkb:CG7656-RA(gene name synonym)|uniprotkb:CG7656(orf name)|uniprotkb:Dmel_CG7656(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108461|imex:IM-9552-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_648783.4|refseq:NP_730058.2|flybase:FBgn0036516|ensemblmetazoa:FBgn0036516(gene)|ensemblmetazoa:FBtr0300329(transcript)|ensemblmetazoa:FBtr0301186(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-8866652|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:coGA0MXK+GugXCL/79B7bYwsKwM7227 intact-crc:C85E3881E170745B|rigid:YZArVImDykMbOJwor7aEBxOhfBY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W3M6 uniprotkb:O97121 intact:EBI-2108471|uniprotkb:Q8T9K9|ensemblmetazoa:FBpp0071083|ensemblmetazoa:FBpp0303850 intact:EBI-2108466 psi-mi:q9w3m6_drome(display_long)|uniprotkb:Dhdds(gene name)|psi-mi:Dhdds(display_short)|uniprotkb:Dmel\CG10778(gene name synonym)|uniprotkb:CG10778(orf name)|uniprotkb:Dmel_CG10778(orf name) psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108474|imex:IM-9552-462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572425.1|flybase:FBgn0029980|refseq:NP_001259316.1|ensemblmetazoa:FBgn0029980(gene)|ensemblmetazoa:FBtr0071131(transcript)|ensemblmetazoa:FBtr0331433(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016094"(polyprenol biosynthetic process)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|interpro:IPR036424|reactome:R-DME-446199 flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:anAI3f3FE8j3i7K2VYT7Od4p+GE7227 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 intact-crc:62DA8131ED4682F8|rigid:WBbUdjQqUFXKbcV4OAYsVpvtjuU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VV76 uniprotkb:Q86P91 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 intact:EBI-870760|ensemblmetazoa:FBpp0077022 psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:q86p91_drome(display_long)|uniprotkb:Syx16(gene name)|psi-mi:Syx16(display_short)|uniprotkb:CG1467(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108479|imex:IM-9552-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 flybase:FBgn0031106|ensemblmetazoa:FBgn0031106(gene)|ensemblmetazoa:FBtr0077330(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 rogid:fbF2zl4Do3qLz31Vn+L/HfthV7k7227 intact-crc:81F5AE40D13EC7D3|rigid:d8Hykp1CtC0Op9ByhqqY91oq7jE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24547 uniprotkb:Q9VV76 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108494|imex:IM-9552-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 intact-crc:048DE642A45C4949|rigid:5Xw5080KcSeyjVfW0h3H9So7Rtg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K0X9 uniprotkb:Q9VV76 intact:EBI-167209|ensemblmetazoa:FBpp0078007|ensemblmetazoa:FBpp0078008|intact:EBI-2108484 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 psi-mi:q7k0x9_drome(display_long)|uniprotkb:Syx7(gene name)|psi-mi:Syx7(display_short)|uniprotkb:Aval(gene name synonym)|uniprotkb:Avl(gene name synonym)|uniprotkb:Dm Syx7(gene name synonym)|uniprotkb:DmSyx7(gene name synonym)|uniprotkb:Dmel\CG5081(gene name synonym)|uniprotkb:FCP-C(gene name synonym)|uniprotkb:SYX7(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:avl(gene name synonym)|uniprotkb:braided(gene name synonym)|uniprotkb:dSyn7(gene name synonym)|uniprotkb:syx7(gene name synonym)|uniprotkb:Dmel_CG5081(orf name)|uniprotkb:CG5081(orf name)|uniprotkb:STX7(gene name synonym) psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108489|imex:IM-9552-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730632.1|refseq:NP_730633.1|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)|ensemblmetazoa:FBgn0267849(gene)|ensemblmetazoa:FBtr0078351(transcript)|ensemblmetazoa:FBtr0078352(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0035073"(pupariation)|flybase:FBgn0267849 refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:i9SFYgLkPP0m5p7BT00RJV6JT/c7227 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 intact-crc:BADD3C2CFD8A14FB|rigid:To910m1v1etsExSuZ1WFIDFU8Dg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VV76 uniprotkb:Q23983 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108499|imex:IM-9552-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:525CDEA6E7496AC7|rigid:S5bAspCyfqNx1FoRKvRdmVmuwtE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W2M2 uniprotkb:Q7KU30 intact:EBI-261090|uniprotkb:Q0E903|uniprotkb:Q0E904|uniprotkb:Q7YWL2|uniprotkb:Q961P0|uniprotkb:Q9W2M1|uniprotkb:Q9W2M3|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 intact:EBI-130703|intact:EBI-9944809|ensemblmetazoa:FBpp0088917|ensemblmetazoa:FBpp0308631|ensemblmetazoa:FBpp0308632|intact:EBI-2108504|uniprotkb:Q9VQP3|uniprotkb:Q9VQP4 psi-mi:trea_drome(display_long)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:CG9364(orf name)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym) psi-mi:q7ku30_drome(display_long)|uniprotkb:E23(gene name)|psi-mi:E23(display_short)|uniprotkb:E23-RC(gene name synonym)|uniprotkb:Dmel_CG3327(orf name)|uniprotkb:Dmel\CG3327(gene name synonym)|uniprotkb:CG15410(gene name synonym)|uniprotkb:CG3327(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108509|imex:IM-9552-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524821.1|refseq:NP_726023.1|refseq:NP_726024.1|refseq:NP_726025.1|refseq:NP_726026.1|refseq:NP_726027.1|flybase:FBgn0003748|refseq:NP_001261115.1|dip:DIP-23202N|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript)|go:"GO:0004555"(alpha,alpha-trehalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005991"(trehalose metabolic process)|go:"GO:0005993"(trehalose catabolic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR001661(Glycoside hydrolase, family 37)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR018232 flybase:FBgn0020445|refseq:NP_524648.3|refseq:NP_608768.2|ensemblmetazoa:FBgn0020445(gene)|ensemblmetazoa:FBtr0089979(transcript)|ensemblmetazoa:FBtr0339548(transcript)|ensemblmetazoa:FBtr0339549(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|refseq:NP_995622.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 rogid:mIdv3fk+l11Y+2QGoTY3PFmorAw7227 intact-crc:8D918D25B5B24744|rigid:bG3J1L4770rKW64wCXkD7b4+4Z8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z8C0 uniprotkb:Q9V3T1 intact:EBI-90156|intact:EBI-2108514|ensemblmetazoa:FBpp0087317 intact:EBI-169390|ensemblmetazoa:FBpp0070165 psi-mi:a1z8c0_drome(display_long)|uniprotkb:mms4(gene name)|psi-mi:mms4(display_short)|uniprotkb:Dmel\CG12936(gene name synonym)|uniprotkb:EME1(gene name synonym)|uniprotkb:CG12936(orf name)|uniprotkb:Dmel_CG12936(orf name) psi-mi:q9v3t1_drome(display_long)|uniprotkb:mus81(gene name)|psi-mi:mus81(display_short)|uniprotkb:"EG:BACR7A4.16"(gene name synonym)|uniprotkb:Dmel\CG3026(gene name synonym)|uniprotkb:Mus81(gene name synonym)|uniprotkb:Dmel_CG3026(orf name)|uniprotkb:CG3026(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108518|imex:IM-9552-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0033549|refseq:NP_610611.1|ensemblmetazoa:FBgn0033549(gene)|ensemblmetazoa:FBtr0088222(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR033310|interpro:IPR042530|reactome:R-DME-5693568 ensemblmetazoa:FBgn0040347(gene)|ensemblmetazoa:FBtr0070170(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0048257"(3'-flap endonuclease activity)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027421|interpro:IPR042530|reactome:R-DME-5693568|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|refseq:NP_569873.1|flybase:FBgn0040347 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VtafzF4JZMsnI/7ZFxSIbJOSD+Y7227 rogid:dfhXcS0xUa4+4ewimRcveZJ+cwY7227 intact-crc:0DB4A1B207E7FA7D|rigid:QQcuqGkPnYuxADGSo7KUxOwaAnw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VPT5 uniprotkb:Q9W0D7 intact:EBI-2108526|uniprotkb:Q4V3Q4|ensemblmetazoa:FBpp0077675|ensemblmetazoa:FBpp0305188 intact:EBI-105831|ensemblmetazoa:FBpp0072626|ensemblmetazoa:FBpp0305589 psi-mi:pex12_drome(display_long)|uniprotkb:Pex12(gene name)|psi-mi:Pex12(display_short)|uniprotkb:Peroxin-12(gene name synonym)|uniprotkb:CG3639(orf name) psi-mi:q9w0d7_drome(display_long)|uniprotkb:CG7864(orf name)|uniprotkb:Pex10(gene name)|psi-mi:Pex10(display_short)|uniprotkb:pex10(gene name synonym)|uniprotkb:Dmel_CG7864(orf name)|uniprotkb:DmelPex10(gene name synonym)|uniprotkb:Dmel\CG7864(gene name synonym)|uniprotkb:PEX10(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108523|imex:IM-9552-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608546.1|flybase:FBgn0031282|refseq:NP_001259844.1|ensemblmetazoa:FBgn0031282(gene)|ensemblmetazoa:FBtr0078010(transcript)|ensemblmetazoa:FBtr0332972(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007286"(spermatid development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0048137"(spermatocyte division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017375(Peroxisome assembly, p12)|reactome:R-DME-8866654|reactome:R-DME-9033241|reactome:R-DME-9603798 refseq:NP_647624.1|flybase:FBgn0035233|refseq:NP_001261265.1|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007285"(primary spermatocyte growth)|go:"GO:0007286"(spermatid development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0048137"(spermatocyte division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-DME-8866654|reactome:R-DME-9033241|ensemblmetazoa:FBgn0035233(gene)|ensemblmetazoa:FBtr0072743(transcript)|ensemblmetazoa:FBtr0333397(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:eXDX/Z4rvM7vAspGzal8WliIEtg7227 rogid:Ex/mjlqBJdbwR3hPnjRxRuGzXcQ7227 intact-crc:CE708944C9FF7F40|rigid:ofx8yMiwMg1MuXdlcK19zi7Eo0I false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VQ02 intact:EBI-2108549 intact:EBI-2108545|ensemblmetazoa:FBpp0077612 - psi-mi:q9vq02_drome(display_long)|uniprotkb:CG5561(orf name)|uniprotkb:Dmel_CG5561(orf name)|uniprotkb:Dmel\CG5561(gene name)|psi-mi:Dmel\CG5561(display_short) psi-mi:a8jqx7_drome(display_short)|psi-mi:EBI-2108549(display_long)|uniprotkb:Dmel_CG14714(orf name)|uniprotkb:CG14714(gene name)|psi-mi:CG14714(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108553|imex:IM-9552-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608596.1|flybase:FBgn0031333|ensemblmetazoa:FBgn0031333(gene)|ensemblmetazoa:FBtr0077947(transcript)|go:"GO:0016791"(phosphatase activity)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR023214|interpro:IPR036412|interpro:IPR041492 uniprotkb:A8JQX7(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:S6mgYWIS90KKmh6pZB4cC5GtQLs7227 rogid:7ewC8wm2qyxHYqZmoHuC/hXPchI7227 intact-crc:AB7DBE972D68E709|rigid:A4B23L8dqlLG9tyLMnBBgBlDEls false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VQE8 uniprotkb:Q8I8U9 intact:EBI-2108535|ensemblmetazoa:FBpp0290208 intact:EBI-2108539|ensemblmetazoa:FBpp0082011 psi-mi:q9vqe8_drome(display_long)|uniprotkb:Trf5(gene name)|psi-mi:Trf5(display_short)|uniprotkb:Dmel\CG15398(gene name synonym)|uniprotkb:trf5(gene name synonym)|uniprotkb:CG15398(orf name)|uniprotkb:Dmel_CG15398(orf name) psi-mi:q8i8u9_drome(display_long)|uniprotkb:CG3169(orf name)|uniprotkb:Spt3(gene name)|psi-mi:Spt3(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108532|imex:IM-9552-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608700.2|flybase:FBgn0031446|ensemblmetazoa:FBgn0031446(gene)|ensemblmetazoa:FBtr0300986(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519 flybase:FBgn0037981|ensemblmetazoa:FBgn0037981(gene)|ensemblmetazoa:FBtr0082537(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|mint:Q8I8U9 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:71ZJ+10WuWeTwm3BkIV5m9+0Z2U7227 rogid:cDszD/qcU5+/mKDsHJQ3zjHjalg7227 intact-crc:4A8A9E741121B50D|rigid:cIDljgnC0KdVZwVU/MVJCU97a3U false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24570 uniprotkb:Q8SZ80 intact:EBI-167445|uniprotkb:Q9VVP6|ensemblmetazoa:FBpp0074896 intact:EBI-870753 psi-mi:grim_drome(display_long)|uniprotkb:grim(gene name)|psi-mi:grim(display_short)|uniprotkb:CG4345(orf name) psi-mi:q8sz80_drome(display_long)|uniprotkb:skl(gene name)|psi-mi:skl(display_short)|uniprotkb:CG13701(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108558|imex:IM-9552-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015946(gene)|ensemblmetazoa:FBtr0075130(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0035006"(melanization defense response)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|rcsb pdb:1JD5|rcsb pdb:1SE0|refseq:NP_524137.2|flybase:FBgn0015946|dip:DIP-20419N flybase:FBgn0036786|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0071479"(cellular response to ionizing radiation) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WvnSy/Je28KP26OK/wqNrhitUsg7227 rogid:hZ5anCD5ybxLCOFz4FQVpklejsc7227 intact-crc:69A9C6182BADBBFB|rigid:YvDF7QJbN9AkryxiydtL5gPNf2Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VVX6 uniprotkb:Q9VE50 intact:EBI-127973|ensemblmetazoa:FBpp0074757|ensemblmetazoa:FBpp0074758 intact:EBI-2108573|uniprotkb:Q8SWZ4|ensemblmetazoa:FBpp0083076 psi-mi:q9vvx6_drome(display_long)|uniprotkb:Bet1(gene name)|psi-mi:Bet1(display_short)|uniprotkb:BET1(gene name synonym)|uniprotkb:"BcDNA:RH40423"(gene name synonym)|uniprotkb:Dm Bet1(gene name synonym)|uniprotkb:Dmel\CG14084(gene name synonym)|uniprotkb:G14084(gene name synonym)|uniprotkb:bs16e01.y1(gene name synonym)|uniprotkb:Dmel_CG14084(orf name)|uniprotkb:CG14084(orf name) psi-mi:gosr1_drome(display_long)|uniprotkb:Gos28(gene name)|psi-mi:Gos28(display_short)|uniprotkb:Probable 28 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:CG7700(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108577|imex:IM-9552-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649096.1|refseq:NP_730391.1|flybase:FBgn0260857|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR039897|interpro:IPR039899|reactome:R-DME-204005|reactome:R-DME-6807878|ensemblmetazoa:FBgn0260857(gene)|ensemblmetazoa:FBtr0074989(transcript)|ensemblmetazoa:FBtr0074990(transcript) refseq:NP_650739.2|flybase:FBgn0044871|ensemblmetazoa:FBgn0044871(gene)|ensemblmetazoa:FBtr0083661(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR023601|reactome:R-DME-6807878|reactome:R-DME-6811438 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:i+4cvQyA5rWLj+2PUfLqsDihTcs7227 rogid:ZCuGd1ZR4KGcybQN1O75sGFCUxU7227 intact-crc:19013711C74C95FC|rigid:XaAbJxrEfZU2NOyktlAvRglF0Ec false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VEJ4 uniprotkb:Q0E8E8 intact:EBI-193861|ensemblmetazoa:FBpp0082929|ensemblmetazoa:FBpp0302818 intact:EBI-141739|ensemblmetazoa:FBpp0075461|ensemblmetazoa:FBpp0075462|ensemblmetazoa:FBpp0300819|intact:EBI-2108566 psi-mi:q9vej4_drome(display_long)|uniprotkb:Dmel\CG5823(gene name)|psi-mi:Dmel\CG5823(display_short)|uniprotkb:Dmel_CG5823(orf name)|uniprotkb:CG5823(orf name) psi-mi:q0e8e8_drome(display_long)|uniprotkb:Mpcp2(gene name)|psi-mi:Mpcp2(display_short)|uniprotkb:Dmel\CG4994(gene name synonym)|uniprotkb:MPCP(gene name synonym)|uniprotkb:Mcpc(gene name synonym)|uniprotkb:Mpcp(gene name synonym)|uniprotkb:Mpcp-RA(gene name synonym)|uniprotkb:PpsM(gene name synonym)|uniprotkb:"l(3)00564"(gene name synonym)|uniprotkb:DmPiC2(gene name synonym)|uniprotkb:mpcp(gene name synonym)|uniprotkb:CG4994(orf name)|uniprotkb:Dmel_CG4994(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108563|imex:IM-9552-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650631.1|flybase:FBgn0038515|refseq:NP_001262669.1|ensemblmetazoa:FBgn0038515(gene)|ensemblmetazoa:FBtr0083505(transcript)|ensemblmetazoa:FBtr0321266(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-DME-9609523|reactome:R-DME-983168 refseq:NP_524069.2|refseq:NP_729978.1|flybase:FBgn0026409|refseq:NP_001246757.1|ensemblmetazoa:FBgn0026409(gene)|ensemblmetazoa:FBtr0075718(transcript)|ensemblmetazoa:FBtr0075719(transcript)|ensemblmetazoa:FBtr0308595(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:2wfBgkNvk+xEwnUlF+HBjVJyJxc7227 rogid:1vbheQY3Za1uaFww6BBY9iqCj+Y7227 intact-crc:03B549E0588F5D34|rigid:DrrQ+O+FJCNkkHyGHGk36s/Wuvk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VE50 uniprotkb:Q23983 intact:EBI-2108573|uniprotkb:Q8SWZ4|ensemblmetazoa:FBpp0083076 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:gosr1_drome(display_long)|uniprotkb:Gos28(gene name)|psi-mi:Gos28(display_short)|uniprotkb:Probable 28 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:CG7700(orf name) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108582|imex:IM-9552-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650739.2|flybase:FBgn0044871|ensemblmetazoa:FBgn0044871(gene)|ensemblmetazoa:FBtr0083661(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR023601|reactome:R-DME-6807878|reactome:R-DME-6811438 refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ZCuGd1ZR4KGcybQN1O75sGFCUxU7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:05EA201B613552E9|rigid:8q+GFkBajPJrt8dAUgwFKG2hFoo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VMH2 uniprotkb:Q9VQD8 intact:EBI-178420|ensemblmetazoa:FBpp0078831 intact:EBI-192564|ensemblmetazoa:FBpp0077378|ensemblmetazoa:FBpp0307163 psi-mi:q9vmh2_drome(display_long)|uniprotkb:Arpc4(gene name)|psi-mi:Arpc4(display_short)|uniprotkb:Arc-p20(gene name synonym)|uniprotkb:Arc-p20-RA(gene name synonym)|uniprotkb:ARPC4(gene name synonym)|uniprotkb:Arp-p20(gene name synonym)|uniprotkb:"BcDNA:RE43724"(gene name synonym)|uniprotkb:Dmel\CG5972(gene name synonym)|uniprotkb:P-20 ARC(gene name synonym)|uniprotkb:"anon-EST:Posey49"(gene name synonym)|uniprotkb:arc-p20(gene name synonym)|uniprotkb:"l(2)SH1036"(gene name synonym)|uniprotkb:"l(2)SH2 1036"(gene name synonym)|uniprotkb:p20(gene name synonym)|uniprotkb:p20Arc(gene name synonym)|uniprotkb:Dmel_CG5972(orf name)|uniprotkb:CG5972(orf name)|uniprotkb:arpc4(gene name synonym) psi-mi:q9vqd8_drome(display_long)|uniprotkb:Arpc5(gene name)|psi-mi:Arpc5(display_short)|uniprotkb:p16-ARC(gene name synonym)|uniprotkb:ARPC5(gene name synonym)|uniprotkb:ArpC5(gene name synonym)|uniprotkb:Dmel\CG9881(gene name synonym)|uniprotkb:P16-ARC(gene name synonym)|uniprotkb:p16(gene name synonym)|uniprotkb:p16-arc(gene name synonym)|uniprotkb:Dmel_CG9881(orf name)|uniprotkb:CG9881(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108587|imex:IM-9552-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608996.1|flybase:FBgn0284255|ensemblmetazoa:FBgn0284255(gene)|ensemblmetazoa:FBtr0079200(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042060"(wound healing)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-8856828 refseq:NP_608693.1|flybase:FBgn0031437|refseq:NP_001259945.1|ensemblmetazoa:FBgn0031437(gene)|ensemblmetazoa:FBtr0077694(transcript)|ensemblmetazoa:FBtr0335170(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-6798695|reactome:R-DME-8856828 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ADwOxfPaPKGZVuZgI+FU3+4Aq8w7227 rogid:wXJwoDydA6Yc4oN3q9b7kiafbkQ7227 intact-crc:D6A57EBD8DF63252|rigid:BqmFzhOxt4dsKrSCEHwcH2SdhHc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNA5 uniprotkb:Q9VJJ0 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108592|imex:IM-9552-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:94F4BDD6D206D482|rigid:Wj3JlV2QTvB0JbJmGvPyRC9JAJg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNA5 uniprotkb:Q9XYN7 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108597|imex:IM-9552-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:DC77D6249B7E65F3|rigid:jEyBIFX2jX6z/1xQ7OW61sQtyPE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNA5 uniprotkb:Q9V3H2 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 intact:EBI-178674|uniprotkb:Q9NIU3|ensemblmetazoa:FBpp0078664 psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:psde_drome(display_long)|uniprotkb:Rpn11(gene name)|psi-mi:Rpn11(display_short)|uniprotkb:CG18174(orf name)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym)|uniprotkb:26S proteasome regulatory complex subunit p37B(gene name synonym)|uniprotkb:Yippee-interacting protein 5(gene name synonym)|uniprotkb:yip5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108602|imex:IM-9552-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N refseq:NP_608905.1|flybase:FBgn0028694|ensemblmetazoa:FBgn0028694(gene)|ensemblmetazoa:FBtr0079027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5689901|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 rogid:7tJj3IGZzTi2DJujVlgT30KGpow7227 intact-crc:612F54754D2BA878|rigid:tx90+NYxAnvkZAs4u24UnoK1Fqg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNA5 uniprotkb:Q7K148 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108607|imex:IM-9552-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 intact-crc:5C4EA404A7264A29|rigid:1ciAsloQx8b+qsO2347KbBktdUY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9VNA5 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108612|imex:IM-9552-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 intact-crc:2A478402A3093891|rigid:teDSifK2s+lAtxLzl4UM/WLLUxw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P25007 uniprotkb:Q9V436 intact:EBI-178070|uniprotkb:Q9VXH8|ensemblmetazoa:FBpp0074017 intact:EBI-126740|ensemblmetazoa:FBpp0075068 psi-mi:ppia_drome(display_long)|uniprotkb:Cyp1(gene name)|psi-mi:Cyp1(display_short)|uniprotkb:Cyp-1(gene name synonym)|uniprotkb:CG9916(orf name)|uniprotkb:Cyclophilin(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:q9v436_drome(display_long)|uniprotkb:Rpn12(gene name)|psi-mi:Rpn12(display_short)|uniprotkb:Dmel\CG4157(gene name synonym)|uniprotkb:S14(gene name synonym)|uniprotkb:dRpn12(gene name synonym)|uniprotkb:p30(gene name synonym)|uniprotkb:Dmel_CG4157(orf name)|uniprotkb:CG4157(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108617|imex:IM-9552-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523366.2|flybase:FBgn0004432|dip:DIP-18774N|ensemblmetazoa:FBgn0004432(gene)|ensemblmetazoa:FBtr0074238(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000 ensemblmetazoa:FBgn0028693(gene)|ensemblmetazoa:FBtr0075308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|refseq:NP_648904.1|flybase:FBgn0028693 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:gnOfxMK/CrIiMAiTXvzdnaCMJZA7227 rogid:1LwtWlEcPX/N0cmArYr46dI9Moc7227 intact-crc:6FD1DF7251AE9BEE|rigid:cbCworuOuh8AsKJ5DJyZ8d7BNwc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95SD3 uniprotkb:Q9VPM0 intact:EBI-2108622 intact:EBI-177124|ensemblmetazoa:FBpp0077802|ensemblmetazoa:FBpp0307924 psi-mi:q95sd3_drome(display_long)|uniprotkb:CG11920(orf name) psi-mi:q9vpm0_drome(display_long)|uniprotkb:Rpp30(gene name)|psi-mi:Rpp30(display_short)|uniprotkb:#19(gene name synonym)|uniprotkb:1(gene name synonym)|uniprotkb:Dmel\CG11606(gene name synonym)|uniprotkb:RNase P(gene name synonym)|uniprotkb:coconut(gene name synonym)|uniprotkb:"l(2)k01901"(gene name synonym)|uniprotkb:Dmel_CG11606(orf name)|uniprotkb:CG11606(orf name)|uniprotkb:Rpp1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108625|imex:IM-9552-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0039274|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281 refseq:NP_524749.1|flybase:FBgn0283652|refseq:NP_001259808.1|ensemblmetazoa:FBgn0283652(gene)|ensemblmetazoa:FBtr0078143(transcript)|ensemblmetazoa:FBtr0336990(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sEiWh5G9OE5QKg0sYyCVvssPeww7227 rogid:qWfqpQ6DXCC6+oQSzslML1rYqnw7227 intact-crc:DA1212242A4D41A7|rigid:WxDHZdERKvR+Q4HjJYZ7dje0YzI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P54399 uniprotkb:Q9W1G0 intact:EBI-123796|uniprotkb:Q9VUL7|uniprotkb:Q53YH5|uniprotkb:Q86PE2|uniprotkb:Q8IQL8|ensemblmetazoa:FBpp0075401|ensemblmetazoa:FBpp0312224 intact:EBI-2108630|ensemblmetazoa:FBpp0072050 psi-mi:pdi_drome(display_long)|uniprotkb:Pdi(gene name)|psi-mi:Pdi(display_short)|uniprotkb:CG6988(orf name) psi-mi:taldo_drome(display_long)|uniprotkb:Taldo(gene name)|psi-mi:Taldo(display_short)|uniprotkb:Tal(gene name synonym)|uniprotkb:CG2827(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108634|imex:IM-9552-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524079.1|refseq:NP_001287070.1|ensemblmetazoa:FBgn0286818(gene)|ensemblmetazoa:FBtr0075648(transcript)|ensemblmetazoa:FBtr0346644(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045169"(fusome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-DME-381426|reactome:R-DME-5358346|reactome:R-DME-8957275|dip:DIP-21766N|flybase:FBgn0286818 refseq:NP_523835.2|flybase:FBgn0023477|ensemblmetazoa:FBgn0023477(gene)|ensemblmetazoa:FBtr0072141(transcript)|go:"GO:0004801"(transaldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|interpro:IPR001585(Transaldolase)|interpro:IPR004730(Transaldolase AB)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018225|reactome:R-DME-163754|reactome:R-DME-71336 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:5WvkcBmjcDkzw5HGvxX9J30oLL47227 rogid:CHevSWRHAVXPZmnGgaI+KfKHS6g7227 intact-crc:6EBA03181299E644|rigid:Rg1cVzGIj/ZopM2F7cVK85HRPk0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V436 uniprotkb:P12881 intact:EBI-126740|ensemblmetazoa:FBpp0075068 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 psi-mi:q9v436_drome(display_long)|uniprotkb:Rpn12(gene name)|psi-mi:Rpn12(display_short)|uniprotkb:Dmel\CG4157(gene name synonym)|uniprotkb:S14(gene name synonym)|uniprotkb:dRpn12(gene name synonym)|uniprotkb:p30(gene name synonym)|uniprotkb:Dmel_CG4157(orf name)|uniprotkb:CG4157(orf name) psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108639|imex:IM-9552-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0028693(gene)|ensemblmetazoa:FBtr0075308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|refseq:NP_648904.1|flybase:FBgn0028693 refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:1LwtWlEcPX/N0cmArYr46dI9Moc7227 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 intact-crc:E2423DD05E54BD1D|rigid:Ryp9zjMv0tVcPiJ+Pe4j1EcgG/g false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1ZBT5 uniprotkb:Q9VIM5 intact:EBI-90766|intact:EBI-2108649|uniprotkb:Q8SZ54|ensemblmetazoa:FBpp0085609 intact:EBI-143351|uniprotkb:Q95T07|ensemblmetazoa:FBpp0080890|ensemblmetazoa:FBpp0312086 psi-mi:med8_drome(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Arc32(gene name synonym)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:CG13867(orf name) psi-mi:arpc2_drome(display_long)|uniprotkb:Arpc2(gene name)|psi-mi:Arpc2(display_short)|uniprotkb:Arc-p34(gene name synonym)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)|uniprotkb:CG10954(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108653|imex:IM-9552-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722456.1|flybase:FBgn0034503|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|ensemblmetazoa:FBtr0086297(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0034503(gene) refseq:NP_610033.1|flybase:FBgn0032859|refseq:NP_001286102.1|dip:DIP-19044N|ensemblmetazoa:FBgn0032859(gene)|ensemblmetazoa:FBtr0081358(transcript)|ensemblmetazoa:FBtr0346418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-8856828 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uo2jUy3XqNhJssWFNY2EhtNwsa87227 rogid:Gsjx/EneyUFSvqD62cD8WqVJxMI7227 intact-crc:78DF2B1E730FDE71|rigid:jNXSMYu2ZHEBTeoPuCEcVnE5YZM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K148 uniprotkb:Q9V436 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 intact:EBI-126740|ensemblmetazoa:FBpp0075068 psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:q9v436_drome(display_long)|uniprotkb:Rpn12(gene name)|psi-mi:Rpn12(display_short)|uniprotkb:Dmel\CG4157(gene name synonym)|uniprotkb:S14(gene name synonym)|uniprotkb:dRpn12(gene name synonym)|uniprotkb:p30(gene name synonym)|uniprotkb:Dmel_CG4157(orf name)|uniprotkb:CG4157(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108644|imex:IM-9552-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 ensemblmetazoa:FBgn0028693(gene)|ensemblmetazoa:FBtr0075308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|refseq:NP_648904.1|flybase:FBgn0028693 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 rogid:1LwtWlEcPX/N0cmArYr46dI9Moc7227 intact-crc:8580C6B73488BC81|rigid:DQ3+IqHLk+EjVbuenZqGmHHrmMw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KBL8 uniprotkb:A1ZBT5 intact:EBI-96589|intact:EBI-2108658|uniprotkb:Q0IGZ7|ensemblmetazoa:FBpp0087251 intact:EBI-90766|intact:EBI-2108649|uniprotkb:Q8SZ54|ensemblmetazoa:FBpp0085609 psi-mi:med29_drome(display_long)|uniprotkb:ix(gene name)|psi-mi:ix(display_short)|uniprotkb:MED29(gene name synonym)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Protein intersex(gene name synonym)|uniprotkb:CG13201(orf name) psi-mi:med8_drome(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Arc32(gene name synonym)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:CG13867(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108663|imex:IM-9552-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610677.1|flybase:FBgn0001276|ensemblmetazoa:FBgn0001276(gene)|ensemblmetazoa:FBtr0088154(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0048804"(imaginal disc-derived female genitalia morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|interpro:IPR021018 refseq:NP_722456.1|flybase:FBgn0034503|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|ensemblmetazoa:FBtr0086297(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0034503(gene) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/1NFeFBg+2kIpzgPP76GaEbvDxU7227 rogid:uo2jUy3XqNhJssWFNY2EhtNwsa87227 intact-crc:33EEEFCD18ED18B7|rigid:+VH8CeV9FD4BImPgCGAOV5sU01U false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JWD6 uniprotkb:A1ZBT5 intact:EBI-162306|intact:EBI-2108668|ensemblmetazoa:FBpp0085724|ensemblmetazoa:FBpp0085725 intact:EBI-90766|intact:EBI-2108649|uniprotkb:Q8SZ54|ensemblmetazoa:FBpp0085609 psi-mi:q7jwd6_drome(display_long)|uniprotkb:EloC(gene name)|psi-mi:EloC(display_short)|uniprotkb:Elongin-C(gene name synonym)|uniprotkb:"BcDNA:RH71704"(gene name synonym)|uniprotkb:Dmel\CG9291(gene name synonym)|uniprotkb:ElonginC(gene name synonym)|uniprotkb:dElongin C(gene name synonym)|uniprotkb:"l(2)SH1299"(gene name synonym)|uniprotkb:"l(2)SH1520"(gene name synonym)|uniprotkb:"l(2)SH2 1520"(gene name synonym)|uniprotkb:CG9291(orf name)|uniprotkb:Dmel_CG9291(orf name) psi-mi:med8_drome(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Arc32(gene name synonym)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:CG13867(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108673|imex:IM-9552-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523794.1|refseq:NP_725894.1|ensemblmetazoa:FBgn0266711(gene)|ensemblmetazoa:FBtr0086540(transcript)|ensemblmetazoa:FBtr0086541(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0016032"(viral process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-DME-112382|reactome:R-DME-1234176|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-75955|reactome:R-DME-8951664|reactome:R-DME-983168|flybase:FBgn0266711 refseq:NP_722456.1|flybase:FBgn0034503|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|ensemblmetazoa:FBtr0086297(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0034503(gene) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:U68k7tnCTTZCUIir5Iu+zAtyXU47227 rogid:uo2jUy3XqNhJssWFNY2EhtNwsa87227 intact-crc:4052CD02061E3DE0|rigid:/HHVTigPqCTcd+DVaxd+R0HLjKE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9VJJ0 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108678|imex:IM-9552-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:33EEB212457EC647|rigid:ckbv5IEu7l4tkPCSq7Zs+T4WI68 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SXB1 uniprotkb:Q9VEK4 intact:EBI-2108683|ensemblmetazoa:FBpp0084340 intact:EBI-95240|ensemblmetazoa:FBpp0082879 psi-mi:q8sxb1_drome(display_long)|uniprotkb:Vps2(gene name)|psi-mi:Vps2(display_short)|uniprotkb:vps2(gene name synonym)|uniprotkb:CG14542(orf name) psi-mi:q9vek4_drome(display_long)|uniprotkb:Dmel\CG5860(gene name)|psi-mi:Dmel\CG5860(display_short)|uniprotkb:FBgn0038506(gene name synonym)|uniprotkb:CG5860(orf name)|uniprotkb:Dmel_CG5860(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108686|imex:IM-9552-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0039402|ensemblmetazoa:FBgn0039402(gene)|ensemblmetazoa:FBtr0084967(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR005024(Snf7) refseq:NP_650622.1|flybase:FBgn0038506|ensemblmetazoa:FBgn0038506(gene)|ensemblmetazoa:FBtr0083438(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|reactome:R-DME-2022377|reactome:R-DME-2132295|reactome:R-DME-5683826 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:539QTjLR85Yu+kvkcKUPlGhvjYg7227 rogid:5CLOFvG7X02wQH9ZEmlA9gk1b4g7227 intact-crc:08C27254E1AA0E7A|rigid:nmfbjB6xlhJxXy/dyzjfQsX7ynA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IGP6 uniprotkb:Q7JVW9 intact:EBI-2108696|ensemblmetazoa:FBpp0081335 intact:EBI-2108704|ensemblmetazoa:FBpp0080089 psi-mi:q8igp6_drome(display_long)|uniprotkb:CG7954(orf name)|uniprotkb:stck(gene name)|psi-mi:stck(display_short) psi-mi:q7jvw9_drome(display_long)|uniprotkb:"BG:BACR48E02.4"(gene name synonym)|uniprotkb:Rsu-1(gene name synonym)|uniprotkb:ics(gene name)|psi-mi:ics(display_short)|uniprotkb:CG9031(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108701|imex:IM-9552-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0020249|ensemblmetazoa:FBgn0020249(gene)|ensemblmetazoa:FBtr0081845(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0008258"(head involution)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031252"(cell leading edge)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH) flybase:FBgn0028546|ensemblmetazoa:FBgn0028546(gene)|ensemblmetazoa:FBtr0080511(transcript)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0lFjf5A/o7UDUbhb0hGJ+XjGg0Q7227 rogid:xcNF5BQmq3TbEcTNIoCZrHlMXEk7227 intact-crc:18E3A654920040E3|rigid:Ddui44IDyDQAoKpXbhURG5JrN9A false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VEK4 uniprotkb:Q9VCU5 intact:EBI-95240|ensemblmetazoa:FBpp0082879 intact:EBI-90141|uniprotkb:Q4V5C0|ensemblmetazoa:FBpp0083715 psi-mi:q9vek4_drome(display_long)|uniprotkb:Dmel\CG5860(gene name)|psi-mi:Dmel\CG5860(display_short)|uniprotkb:FBgn0038506(gene name synonym)|uniprotkb:CG5860(orf name)|uniprotkb:Dmel_CG5860(orf name) psi-mi:mtg1_drome(display_long)|uniprotkb:Mitochondrial GTPase 1(gene name synonym)|uniprotkb:CG17141(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108691|imex:IM-9552-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650622.1|flybase:FBgn0038506|ensemblmetazoa:FBgn0038506(gene)|ensemblmetazoa:FBtr0083438(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|reactome:R-DME-2022377|reactome:R-DME-2132295|reactome:R-DME-5683826 refseq:NP_651094.2|flybase:FBgn0039020|ensemblmetazoa:FBgn0039020(gene)|ensemblmetazoa:FBtr0084322(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|interpro:IPR006073(GTP1/OBG)|interpro:IPR016478(GTPase, MG442, predicted)|interpro:IPR023179|interpro:IPR027417|interpro:IPR030378 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:5CLOFvG7X02wQH9ZEmlA9gk1b4g7227 rogid:gokYIKjvj+whybtfmBVsAGRV3qI7227 intact-crc:396DD09E0FE7F22B|rigid:kqofCvK5ytOT9QMjmT+w+T4uFWE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q86P91 uniprotkb:Q23983 intact:EBI-870760|ensemblmetazoa:FBpp0077022 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:q86p91_drome(display_long)|uniprotkb:Syx16(gene name)|psi-mi:Syx16(display_short)|uniprotkb:CG1467(orf name) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108715|imex:IM-9552-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0031106|ensemblmetazoa:FBgn0031106(gene)|ensemblmetazoa:FBtr0077330(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673 refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fbF2zl4Do3qLz31Vn+L/HfthV7k7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:8C589B88B29DB54D|rigid:QGGKNG0VrZvyx8qXCtH76KzHHag false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K5M6 uniprotkb:Q9VA91 intact:EBI-119229|intact:EBI-2108720|ensemblmetazoa:FBpp0086065 intact:EBI-97643|uniprotkb:A4V3N0|ensemblmetazoa:FBpp0088439|ensemblmetazoa:FBpp0088440|ensemblmetazoa:FBpp0088970|ensemblmetazoa:FBpp0308324 psi-mi:q7k5m6_drome(display_long)|uniprotkb:Sip1(gene name)|psi-mi:Sip1(display_short)|uniprotkb:Dmel\CG10939(gene name synonym)|uniprotkb:"l(2)06373"(gene name synonym)|uniprotkb:CG10939(orf name)|uniprotkb:Dmel_CG10939(orf name) psi-mi:rs7_drome(display_long)|uniprotkb:CG1883(orf name)|uniprotkb:RpS7(gene name)|psi-mi:RpS7(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108725|imex:IM-9552-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524712.1|flybase:FBgn0010620|ensemblmetazoa:FBgn0010620(gene)|ensemblmetazoa:FBtr0086909(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0098801"(regulation of renal system process)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034 refseq:NP_651782.1|refseq:NP_733355.1|refseq:NP_996312.1|flybase:FBgn0039757|ensemblmetazoa:FBgn0039757(gene)|ensemblmetazoa:FBtr0089422(transcript)|ensemblmetazoa:FBtr0089423(transcript)|ensemblmetazoa:FBtr0089425(transcript)|ensemblmetazoa:FBtr0339183(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR000554(Ribosomal protein S7e)|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-6791226|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-975956|reactome:R-DME-975957|refseq:NP_733356.2 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:2bqHf9vMZY+33ptbbsD+yT0rCFQ7227 rogid:K+Lbl1YMT+Bq7MqV93L7dptxLNQ7227 intact-crc:6C5BC0AF5A0FE21D|rigid:ZcSlEiRL/9wM1Ln/jssbPSvR2Kc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q86P91 uniprotkb:Q9W0N6 intact:EBI-870760|ensemblmetazoa:FBpp0077022 intact:EBI-119356|ensemblmetazoa:FBpp0072503 psi-mi:q86p91_drome(display_long)|uniprotkb:Syx16(gene name)|psi-mi:Syx16(display_short)|uniprotkb:CG1467(orf name) psi-mi:q9w0n6_drome(display_long)|uniprotkb:Vti1a(gene name)|psi-mi:Vti1a(display_short)|uniprotkb:Vti1(gene name synonym)|uniprotkb:Dmel\CG3279(gene name synonym)|uniprotkb:VTI1(gene name synonym)|uniprotkb:Vti1A(gene name synonym)|uniprotkb:vti1a(gene name synonym)|uniprotkb:CG3279(orf name)|uniprotkb:Dmel_CG3279(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108710|imex:IM-9552-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0031106|ensemblmetazoa:FBgn0031106(gene)|ensemblmetazoa:FBtr0077330(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673 refseq:NP_612053.1|flybase:FBgn0260862|ensemblmetazoa:FBgn0260862(gene)|ensemblmetazoa:FBtr0072607(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fbF2zl4Do3qLz31Vn+L/HfthV7k7227 rogid:zNV6ODbviT5S3Xp6A6VYaJA1FCg7227 intact-crc:A48DAAC8E1B0B73D|rigid:go2mKy4mc9CYQPNaLH3UMP+T6yY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P13008 uniprotkb:Q9VBI0 intact:EBI-171405|uniprotkb:A4V0T7|uniprotkb:P10380|uniprotkb:Q0E8P4|uniprotkb:Q9VJ88|uniprotkb:C0PV38|ensemblmetazoa:FBpp0080639|ensemblmetazoa:FBpp0080640|ensemblmetazoa:FBpp0080641|ensemblmetazoa:FBpp0303872|ensemblmetazoa:FBpp0312181 intact:EBI-170896|ensemblmetazoa:FBpp0084341 psi-mi:rs26_drome(display_long)|uniprotkb:RpS26(gene name)|psi-mi:RpS26(display_short)|uniprotkb:CG10305(orf name) psi-mi:q9vbi0_drome(display_long)|uniprotkb:Dmel\CG14543(gene name)|psi-mi:Dmel\CG14543(display_short)|uniprotkb:CG14543(orf name)|uniprotkb:Dmel_CG14543(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108730|imex:IM-9552-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286042.1|refseq:NP_523595.1|refseq:NP_724109.1|refseq:NP_724110.1|flybase:FBgn0261597|refseq:NP_001260537.1|dip:DIP-17487N|ensemblmetazoa:FBgn0261597(gene)|ensemblmetazoa:FBtr0081089(transcript)|ensemblmetazoa:FBtr0081090(transcript)|ensemblmetazoa:FBtr0081091(transcript)|ensemblmetazoa:FBtr0331455(transcript)|ensemblmetazoa:FBtr0346591(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-975956|reactome:R-DME-975957 refseq:NP_651458.1|flybase:FBgn0039404|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|interpro:IPR019398|ensemblmetazoa:FBgn0039404(gene)|ensemblmetazoa:FBtr0084968(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:DeTsUMrxIw8cO3N4R6xN+YSVn8A7227 rogid:4U/x22vL0MotUJ8kxH3pcDr9yrI7227 intact-crc:6490F9BD8BAFD2AC|rigid:97OarX8s5muGg0vMWf36wMyZcVU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q23983 uniprotkb:Q9VN02 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 intact:EBI-114729|ensemblmetazoa:FBpp0078598|ensemblmetazoa:FBpp0312584 psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:q9vn02_drome(display_long)|uniprotkb:CG9779(orf name)|uniprotkb:Vps24(gene name)|psi-mi:Vps24(display_short)|uniprotkb:vps24(gene name synonym)|uniprotkb:Dmel_CG9779(orf name)|uniprotkb:DmVPS24(gene name synonym)|uniprotkb:Dmel\CG9779(gene name synonym)|uniprotkb:ESCRT(gene name synonym)|uniprotkb:dvps24(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108735|imex:IM-9552-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 refseq:NP_649451.1|flybase:FBgn0037231|ensemblmetazoa:FBgn0037231(gene)|ensemblmetazoa:FBtr0078958(transcript)|ensemblmetazoa:FBtr0347550(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|interpro:IPR005024(Snf7)|reactome:R-DME-1632852|reactome:R-DME-917729|reactome:R-DME-9668328|refseq:NP_001303457.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 rogid:qF5M48skW/1ulD6kW41hHeOJuek7227 intact-crc:D2A6C840AA7621C0|rigid:U2/7UqOzS41fviElw7edCvKB1vY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VIH0 uniprotkb:Q9VPB8 intact:EBI-2108743|ensemblmetazoa:FBpp0088883 intact:EBI-113203|ensemblmetazoa:FBpp0077909 psi-mi:q9vih0_drome(display_long)|uniprotkb:"Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase"(gene name synonym)|uniprotkb:NTH1(gene name)|psi-mi:NTH1(display_short)|uniprotkb:Nthl1(gene name synonym)|uniprotkb:CG9272(orf name)|uniprotkb:Dmel_CG9272(orf name)|uniprotkb:9272(gene name synonym)|uniprotkb:Dmel\CG9272(gene name synonym)|uniprotkb:Nth1(gene name synonym) psi-mi:q9vpb8_drome(display_long)|uniprotkb:CG4289(orf name)|uniprotkb:Pex14(gene name)|psi-mi:Pex14(display_short)|uniprotkb:Dmel\CG4289(gene name synonym)|uniprotkb:PEX14(gene name synonym)|uniprotkb:DmelPex14(gene name synonym)|uniprotkb:Dmel_CG4289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108740|imex:IM-9552-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610078.2|flybase:FBgn0032907|ensemblmetazoa:FBgn0032907(gene)|ensemblmetazoa:FBtr0089944(transcript)|go:"GO:0000703"(oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR003265(HhH-GPD)|interpro:IPR003651(Iron-sulphur cluster loop)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR011257(DNA glycosylase)|interpro:IPR023170|interpro:IPR030841|reactome:R-DME-110329|reactome:R-DME-110357 refseq:NP_649253.1|flybase:FBgn0037020|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|reactome:R-DME-8866654|reactome:R-DME-9033241|reactome:R-DME-9603798|ensemblmetazoa:FBgn0037020(gene)|ensemblmetazoa:FBtr0078251(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Zl/mko4wT7ZJV/YM8C/tbQFHzis7227 rogid:8epj172rsdmZTGARiPgaNLMmhHw7227 intact-crc:367135B15EC1B378|rigid:jHhff92/a4rKkESNNZriutK/sck false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VBH7 uniprotkb:Q8MS69 intact:EBI-86202|ensemblmetazoa:FBpp0084342|ensemblmetazoa:FBpp0312340 intact:EBI-2108749|ensemblmetazoa:FBpp0078961|ensemblmetazoa:FBpp0309857|ensemblmetazoa:FBpp0309858 psi-mi:q9vbh7_drome(display_long)|uniprotkb:Dmel\CG14544(gene name)|psi-mi:Dmel\CG14544(display_short)|uniprotkb:Dmel_CG14544(orf name)|uniprotkb:CG14544(orf name) psi-mi:q8ms69_drome(display_long)|uniprotkb:CG9596(orf name)|uniprotkb:Dmel_CG9596(orf name)|uniprotkb:Dmel\CG9596(gene name)|psi-mi:Dmel\CG9596(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108753|imex:IM-9552-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651461.1|flybase:FBgn0039407|refseq:NP_001303484.1|ensemblmetazoa:FBgn0039407(gene)|ensemblmetazoa:FBtr0084969(transcript)|ensemblmetazoa:FBtr0346731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|interpro:IPR014816(tRNA methyltransferase complex GCD14 subunit)|interpro:IPR029063 refseq:NP_995638.1|flybase:FBgn0031832|refseq:NP_001285679.1|refseq:NP_609048.2|ensemblmetazoa:FBgn0031832(gene)|ensemblmetazoa:FBtr0079332(transcript)|ensemblmetazoa:FBtr0343162(transcript)|ensemblmetazoa:FBtr0343163(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|interpro:IPR017423("tRNA (adenine-N(1)-)-methyltransferase, non-catalytic TRM6 subunit") psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:KN7gMASJ2pxz9XKWZRABwFmqbK87227 rogid:+aQRiNivaBuZ75D7aDm8masiVNg7227 intact-crc:6985E2E5D0312B2C|rigid:zWXLYT+uAHO2gTagG8oneSR2OuE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VPM0 uniprotkb:Q8MS69 intact:EBI-177124|ensemblmetazoa:FBpp0077802|ensemblmetazoa:FBpp0307924 intact:EBI-2108749|ensemblmetazoa:FBpp0078961|ensemblmetazoa:FBpp0309857|ensemblmetazoa:FBpp0309858 psi-mi:q9vpm0_drome(display_long)|uniprotkb:Rpp30(gene name)|psi-mi:Rpp30(display_short)|uniprotkb:#19(gene name synonym)|uniprotkb:1(gene name synonym)|uniprotkb:Dmel\CG11606(gene name synonym)|uniprotkb:RNase P(gene name synonym)|uniprotkb:coconut(gene name synonym)|uniprotkb:"l(2)k01901"(gene name synonym)|uniprotkb:Dmel_CG11606(orf name)|uniprotkb:CG11606(orf name)|uniprotkb:Rpp1(gene name synonym) psi-mi:q8ms69_drome(display_long)|uniprotkb:CG9596(orf name)|uniprotkb:Dmel_CG9596(orf name)|uniprotkb:Dmel\CG9596(gene name)|psi-mi:Dmel\CG9596(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108758|imex:IM-9552-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524749.1|flybase:FBgn0283652|refseq:NP_001259808.1|ensemblmetazoa:FBgn0283652(gene)|ensemblmetazoa:FBtr0078143(transcript)|ensemblmetazoa:FBtr0336990(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like) refseq:NP_995638.1|flybase:FBgn0031832|refseq:NP_001285679.1|refseq:NP_609048.2|ensemblmetazoa:FBgn0031832(gene)|ensemblmetazoa:FBtr0079332(transcript)|ensemblmetazoa:FBtr0343162(transcript)|ensemblmetazoa:FBtr0343163(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|interpro:IPR017423("tRNA (adenine-N(1)-)-methyltransferase, non-catalytic TRM6 subunit") psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:qWfqpQ6DXCC6+oQSzslML1rYqnw7227 rogid:+aQRiNivaBuZ75D7aDm8masiVNg7227 intact-crc:A8D6EF84332EDFCC|rigid:V8fRT659zE6CGvFKL39TN4yStCw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P61851 uniprotkb:A1Z850 intact:EBI-97942|uniprotkb:P00444|uniprotkb:Q27770|uniprotkb:Q9VTF6|ensemblmetazoa:FBpp0075958 intact:EBI-142201|intact:EBI-2108766|ensemblmetazoa:FBpp0305282 psi-mi:sodc_drome(display_long)|uniprotkb:Sod1(gene name)|psi-mi:Sod1(display_short)|uniprotkb:Sod(gene name synonym)|uniprotkb:Superoxide dismutase 1(gene name synonym)|uniprotkb:CG11793(orf name) psi-mi:a1z850_drome(display_long)|uniprotkb:Ccs(gene name)|psi-mi:Ccs(display_short)|uniprotkb:CCS(gene name synonym)|uniprotkb:CCD(gene name synonym)|uniprotkb:CG-17753(gene name synonym)|uniprotkb:DmCCS(gene name synonym)|uniprotkb:Dmel\CG17753(gene name synonym)|uniprotkb:"anon-EST:Posey231"(gene name synonym)|uniprotkb:dCCS(gene name synonym)|uniprotkb:"l(2)03221"(gene name synonym)|uniprotkb:CG17753(orf name)|uniprotkb:Dmel_CG17753(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108763|imex:IM-9552-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476735.1|flybase:FBgn0003462|ensemblmetazoa:FBgn0003462(gene)|ensemblmetazoa:FBtr0076229(transcript)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036423|reactome:R-DME-114608|reactome:R-DME-3299685 flybase:FBgn0010531|refseq:NP_652029.3|ensemblmetazoa:FBgn0010531(gene)|ensemblmetazoa:FBtr0333068(transcript)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036423 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2015/04/29 rogid:joHUZ1CVxXt56OU7vv2cX60MJDE7227 rogid:UOMbnTZAY3xIw18oWpAyzJce5Rs7227 intact-crc:CF9ECBD92143C4E9|rigid:IDeTxnftNnTLMoJ8xp6EoNl0fy4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VKW3 uniprotkb:Q9VN95 intact:EBI-118156|uniprotkb:Q9NGN8|ensemblmetazoa:FBpp0079609 intact:EBI-112613|uniprotkb:Q4V3F1|ensemblmetazoa:FBpp0078463 psi-mi:q9vkw3_drome(display_long)|uniprotkb:RfC3(gene name)|psi-mi:RfC3(display_short)|uniprotkb:CG5313(orf name)|uniprotkb:DRFC(gene name synonym)|uniprotkb:DmRFC3(gene name synonym)|uniprotkb:Dmel\CG5313(gene name synonym)|uniprotkb:Rfc3(gene name synonym)|uniprotkb:Dmel_CG5313(orf name) psi-mi:enoph_drome(display_long)|uniprotkb:2,3-diketo-5-methylthio-1-phosphopentane phosphatase(gene name synonym)|uniprotkb:CG12173(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108772|imex:IM-9552-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609399.1|flybase:FBgn0032244|ensemblmetazoa:FBgn0032244(gene)|ensemblmetazoa:FBtr0080019(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-174411|reactome:R-DME-176187|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696397|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-69091 refseq:NP_649523.1|flybase:FBgn0037305|ensemblmetazoa:FBgn0037305(gene)|ensemblmetazoa:FBtr0078821(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0043715"(2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity)|go:"GO:0043716"(2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity)|go:"GO:0043874"(acireductone synthase activity)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023214|interpro:IPR023943|interpro:IPR027511|interpro:IPR036412|reactome:R-DME-1237112 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:NVFRniFabAzSoVPVU0MgLhkoYCo7227 rogid:QqGxjD9oxujrWMaFD8zA/vVp18o7227 intact-crc:51201F3BE25EC790|rigid:om8NS+bJFb1yYwDXP+6/EAWTl6M false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN50 uniprotkb:Q9U1H8 intact:EBI-87054|ensemblmetazoa:FBpp0078532 intact:EBI-2108782|uniprotkb:Q8SZZ3|uniprotkb:Q9VRM4|ensemblmetazoa:FBpp0076791 psi-mi:ei3f1_drome(display_long)|uniprotkb:eIF3f1(gene name)|psi-mi:eIF3f1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5-1(gene name synonym)|uniprotkb:eIF3-S5-1(gene name synonym)|uniprotkb:CG9769(orf name) psi-mi:face2_drome(display_long)|uniprotkb:Protein severas(gene name synonym)|uniprotkb:CG4852(orf name)|uniprotkb:Farnesylated proteins-converting enzyme 2(gene name synonym)|uniprotkb:Prenyl protein-specific endoprotease 2(gene name synonym)|uniprotkb:Sras(gene name)|psi-mi:Sras(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108787|imex:IM-9552-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0037270(gene)|ensemblmetazoa:FBtr0078892(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|reactome:R-DME-156827|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|refseq:NP_649489.1|flybase:FBgn0037270 refseq:NP_524673.3|flybase:FBgn0029121|ensemblmetazoa:FBgn0029121(gene)|ensemblmetazoa:FBtr0077083(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071586"(CAAX-box protein processing)|interpro:IPR003675(Abortive infection protein)|interpro:IPR039731|reactome:R-DME-5689880|reactome:R-DME-9648002 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:P3H8lpj2bTJSidtbcDvAR11xaps7227 rogid:aYHNi4+/peKKqQNmaAfPS/GlQH47227 intact-crc:1BE4752C49706208|rigid:p6eXMoVYD/JrcOzCqt8O6uOX01g false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q27580 uniprotkb:Q0E924 intact:EBI-171029|uniprotkb:Q8MZI1|uniprotkb:Q9VXV5|ensemblmetazoa:FBpp0073847|ensemblmetazoa:FBpp0312000 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 psi-mi:sahh_drome(display_long)|uniprotkb:Ahcy13(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:Ahcy(gene name)|psi-mi:Ahcy(display_short)|uniprotkb:CG11654(orf name) psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108777|imex:IM-9552-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511164.2|flybase:FBgn0014455|refseq:NP_001285268.1|ensemblmetazoa:FBgn0014455(gene)|ensemblmetazoa:FBtr0074030(transcript)|ensemblmetazoa:FBtr0346181(transcript)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0033353"(S-adenosylmethionine cycle)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|reactome:R-DME-156581|reactome:R-DME-1614635|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase) refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ZmEZd3e7LCzNr2ugVF1bE5+tyTE7227 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 intact-crc:B2517B9E90CD8549|rigid:tdoyvsyrzrFeqwAZUrh2nvfPDbA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z7F2 uniprotkb:Q95T33 intact:EBI-2108805|ensemblmetazoa:FBpp0087836|ensemblmetazoa:FBpp0311600 intact:EBI-2108802|ensemblmetazoa:FBpp0085146 psi-mi:a1z7f2_drome(display_long)|uniprotkb:Mal-A7(gene name)|psi-mi:Mal-A7(display_short)|uniprotkb:CT36683(gene name synonym)|uniprotkb:Dmel\CG11669(gene name synonym)|uniprotkb:Drome_A7(gene name synonym)|uniprotkb:mal_A7(gene name synonym)|uniprotkb:CG11669(orf name)|uniprotkb:Dmel_CG11669(orf name) psi-mi:q95t33_drome(display_long)|uniprotkb:CG1607(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108809|imex:IM-9552-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610383.1|flybase:FBgn0033296|refseq:NP_001286198.1|ensemblmetazoa:FBgn0033296(gene)|ensemblmetazoa:FBtr0088757(transcript)|ensemblmetazoa:FBtr0345489(transcript)|go:"GO:0032450"(maltose alpha-glucosidase activity)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|reactome:R-DME-352230 flybase:FBgn0039844|ensemblmetazoa:FBgn0039844(gene)|ensemblmetazoa:FBtr0085785(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:MoNUMsKlQVbqVRIg6FU2WpvdTb07227 rogid:9PnvIdl/ByaccSkUXnIeJvbmTUI7227 intact-crc:0F2FE30130FFE875|rigid:b8z3XNVwjvNjKrgt2GpcITWjXQY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P02572 uniprotkb:Q8SY43 intact:EBI-110368|uniprotkb:Q24228|uniprotkb:Q540X3|uniprotkb:Q9V9J4|ensemblmetazoa:FBpp0085365 intact:EBI-2108792 psi-mi:act2_drome(display_long)|uniprotkb:Act42A(gene name)|psi-mi:Act42A(display_short)|uniprotkb:CG12051(orf name) psi-mi:q8sy43_drome(display_long)|uniprotkb:CG5797(gene name synonym)|uniprotkb:Fhos(gene name)|psi-mi:Fhos(display_short)|uniprotkb:CG42610(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108797|imex:IM-9552-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523625.1|flybase:FBgn0000043|dip:DIP-20355N|ensemblmetazoa:FBgn0000043(gene)|ensemblmetazoa:FBtr0086029(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0035060"(brahma complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129 flybase:FBgn0266084|go:"GO:0003012"(muscle system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041387|interpro:IPR042201 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YeeXgsuRY2BQ3DVxG7MuVmol+bo7227 rogid:9+XLeoTFndd4NUHjrW8p5VKgAMc7227 intact-crc:E599D07FEF507537|rigid:fbcfbCmfrSXmZr1JZ/7MKAn+PG8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q6NR18 uniprotkb:Q5U127 intact:EBI-2108814 intact:EBI-2108819|ensemblmetazoa:FBpp0293514 psi-mi:q6nr18_drome(display_long)|uniprotkb:Pld(gene name)|psi-mi:Pld(display_short)|uniprotkb:CG12110(orf name) psi-mi:q5u127_drome(display_long)|uniprotkb:CG6169(orf name)|uniprotkb:"BEST:LD07107"(gene name synonym)|uniprotkb:DCp2p(gene name synonym)|uniprotkb:Dmel\CG6169(gene name synonym)|uniprotkb:LD07107(gene name synonym)|uniprotkb:dDCP2(gene name synonym)|uniprotkb:dDcp(gene name synonym)|uniprotkb:dDcp2(gene name synonym)|uniprotkb:dcp2(gene name synonym)|uniprotkb:Dmel_CG6169(orf name)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Dcp2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108823|imex:IM-9552-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0286511|go:"GO:0004630"(phospholipase D activity)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007349"(cellularization)|go:"GO:0007602"(phototransduction)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048215"(positive regulation of Golgi vesicle fusion to target membrane)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR036871 flybase:FBgn0036534|refseq:NP_001246776.1|ensemblmetazoa:FBgn0036534(gene)|ensemblmetazoa:FBtr0304975(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0045495"(pole plasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0051015"(actin filament binding)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|reactome:R-DME-430039|reactome:R-DME-450385|reactome:R-DME-450513 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o6ATxLbRQIQbVWqBeUlQCXkKktM7227 rogid:tHmfiFVFS9g1efAZYjOeLj0o4wg7227 intact-crc:094F117EFC8441B9|rigid:U6hemooWzKUEXfOEpp7Lw4ZDk6Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VHJ4 uniprotkb:Q8SXQ9 intact:EBI-166206|ensemblmetazoa:FBpp0081491 intact:EBI-2108833|uniprotkb:Q9VG90|ensemblmetazoa:FBpp0082048 psi-mi:q9vhj4_drome(display_long)|uniprotkb:B(gene name synonym)|uniprotkb:Dmel\CG11968(gene name synonym)|uniprotkb:Gtr1(gene name synonym)|uniprotkb:Rag(gene name synonym)|uniprotkb:dRagA(gene name synonym)|uniprotkb:dRagB(gene name synonym)|uniprotkb:rag(gene name synonym)|uniprotkb:ragA(gene name synonym)|uniprotkb:Dmel_CG11968(orf name)|uniprotkb:RagA-B(gene name)|psi-mi:RagA-B(display_short)|uniprotkb:RagA(gene name synonym)|uniprotkb:CG11968(orf name)|uniprotkb:Rag A(gene name synonym) psi-mi:q8sxq9_drome(display_long)|uniprotkb:CG17639(orf name)|uniprotkb:GstD11(gene name)|psi-mi:GstD11(display_short)|uniprotkb:cg17639(gene name synonym)|uniprotkb:"BcDNA:RE72392"(gene name synonym)|uniprotkb:DmGSTD11(gene name synonym)|uniprotkb:Dmel\CG17639(gene name synonym)|uniprotkb:GSTD11(gene name synonym)|uniprotkb:gstd11(gene name synonym)|uniprotkb:Dmel_CG17639(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108836|imex:IM-9552-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0037647(gene)|ensemblmetazoa:FBtr0082013(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|reactome:R-DME-1632852|reactome:R-DME-166208|reactome:R-DME-165159|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|refseq:NP_649850.1|flybase:FBgn0037647 refseq:NP_650183.1|flybase:FBgn0038029|ensemblmetazoa:FBgn0038029(gene)|ensemblmetazoa:FBtr0082576(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:748OZSJ3gq3R/v/iFZk/dWd0ORw7227 rogid:U5SnuNlvbNONohNCTTAPPKRIq607227 intact-crc:708E4D2AB7269857|rigid:9MgDITrQ0dfhAOqiTxNTyaEezv8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P02572 uniprotkb:Q6NR18 intact:EBI-110368|uniprotkb:Q24228|uniprotkb:Q540X3|uniprotkb:Q9V9J4|ensemblmetazoa:FBpp0085365 intact:EBI-2108814 psi-mi:act2_drome(display_long)|uniprotkb:Act42A(gene name)|psi-mi:Act42A(display_short)|uniprotkb:CG12051(orf name) psi-mi:q6nr18_drome(display_long)|uniprotkb:Pld(gene name)|psi-mi:Pld(display_short)|uniprotkb:CG12110(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108828|imex:IM-9552-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523625.1|flybase:FBgn0000043|dip:DIP-20355N|ensemblmetazoa:FBgn0000043(gene)|ensemblmetazoa:FBtr0086029(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0035060"(brahma complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129 flybase:FBgn0286511|go:"GO:0004630"(phospholipase D activity)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007349"(cellularization)|go:"GO:0007602"(phototransduction)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048215"(positive regulation of Golgi vesicle fusion to target membrane)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR036871 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YeeXgsuRY2BQ3DVxG7MuVmol+bo7227 rogid:o6ATxLbRQIQbVWqBeUlQCXkKktM7227 intact-crc:4524436F2B4573DE|rigid:ujG12SRxx3tHHs0isgtsAelDbPA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P91938 uniprotkb:Q9VVL7 intact:EBI-208742|uniprotkb:Q961E3|uniprotkb:Q9W3H2|uniprotkb:Q9W3H3|uniprotkb:Q1RKZ0|uniprotkb:Q53YG2|ensemblmetazoa:FBpp0071116 intact:EBI-110434|ensemblmetazoa:FBpp0074906|ensemblmetazoa:FBpp0304195 psi-mi:trxr1_drome(display_long)|uniprotkb:Trxr-1(gene name)|psi-mi:Trxr-1(display_short)|uniprotkb:GR(gene name synonym)|uniprotkb:CG2151(orf name) psi-mi:q9vvl7_drome(display_long)|uniprotkb:E3(gene name)|psi-mi:E3(display_short)|uniprotkb:Dmel\CG7430(gene name synonym)|uniprotkb:CG7430(orf name)|uniprotkb:Dmel_CG7430(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108841|imex:IM-9552-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511082.2|refseq:NP_727251.1|refseq:NP_727252.1|flybase:FBgn0020653|dip:DIP-19145N|ensemblmetazoa:FBgn0020653(gene)|ensemblmetazoa:FBtr0071168(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016209"(antioxidant activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2NVK|rcsb pdb:3DGH|rcsb pdb:3DH9|reactome:R-DME-3299685|reactome:R-DME-499943|reactome:R-DME-5263617|reactome:R-DME-5628897 refseq:NP_649017.1|flybase:FBgn0036762|refseq:NP_001262000.1|ensemblmetazoa:FBgn0036762(gene)|ensemblmetazoa:FBtr0075140(transcript)|ensemblmetazoa:FBtr0331810(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|reactome:R-DME-204174|reactome:R-DME-389661|reactome:R-DME-5362517|reactome:R-DME-6783984|reactome:R-DME-70268|reactome:R-DME-70895|reactome:R-DME-71064|reactome:R-DME-71403 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9UYtoqz7kwWtFnWOX8rmwyYlY9M7227 rogid:Z1ikpHda8Rx9t/G3w2o9rhqbxE07227 intact-crc:A853F09429B29308|rigid:AXeiDqOrlVefFlh4Z29awI+Jg8c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P21914 uniprotkb:Q9VVL7 intact:EBI-136047|uniprotkb:Q9V9A0|ensemblmetazoa:FBpp0085489 intact:EBI-110434|ensemblmetazoa:FBpp0074906|ensemblmetazoa:FBpp0304195 psi-mi:sdhb_drome(display_long)|uniprotkb:SdhB(gene name)|psi-mi:SdhB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:CG3283(orf name)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym) psi-mi:q9vvl7_drome(display_long)|uniprotkb:E3(gene name)|psi-mi:E3(display_short)|uniprotkb:Dmel\CG7430(gene name synonym)|uniprotkb:CG7430(orf name)|uniprotkb:Dmel_CG7430(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108846|imex:IM-9552-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-DME-71403|refseq:NP_477101.1|flybase:FBgn0014028|ensemblmetazoa:FBgn0014028(gene)|ensemblmetazoa:FBtr0086156(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0009055"(electron transfer activity)|dip:DIP-20115N refseq:NP_649017.1|flybase:FBgn0036762|refseq:NP_001262000.1|ensemblmetazoa:FBgn0036762(gene)|ensemblmetazoa:FBtr0075140(transcript)|ensemblmetazoa:FBtr0331810(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|reactome:R-DME-204174|reactome:R-DME-389661|reactome:R-DME-5362517|reactome:R-DME-6783984|reactome:R-DME-70268|reactome:R-DME-70895|reactome:R-DME-71064|reactome:R-DME-71403 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xtvWH/0V/SoBZ6cfsHV7vnjugKw7227 rogid:Z1ikpHda8Rx9t/G3w2o9rhqbxE07227 intact-crc:02C4BC5DA32E7B38|rigid:2qQso30vBcEOLXl7gwAFO09YvS8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTL5 uniprotkb:Q7K1Q7 intact:EBI-106526|ensemblmetazoa:FBpp0075865|ensemblmetazoa:FBpp0075866 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 psi-mi:q9vtl5_drome(display_long)|uniprotkb:CG11660(orf name)|uniprotkb:RIOK1(gene name)|psi-mi:RIOK1(display_short)|uniprotkb:Dmel\CG11660(gene name synonym)|uniprotkb:Rio1(gene name synonym)|uniprotkb:dRIOK1(gene name synonym)|uniprotkb:Dmel_CG11660(orf name) psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108856|imex:IM-9552-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648489.1|refseq:NP_729730.1|flybase:FBgn0036187|ensemblmetazoa:FBgn0036187(gene)|ensemblmetazoa:FBtr0076134(transcript)|ensemblmetazoa:FBtr0076135(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0046872"(metal ion binding)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000687(RIO kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935 refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:FelATUt0mFsZiTPQlkok642iRmY7227 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 intact-crc:9E6ECF6669F6D884|rigid:qreKnM9Mms5o2ToQt/pLqfbtNcA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97121 uniprotkb:P31009 intact:EBI-2108466 intact:EBI-181495|uniprotkb:Q9VL74|ensemblmetazoa:FBpp0079500|ensemblmetazoa:FBpp0303531|ensemblmetazoa:FBpp0311561 psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:rs2_drome(display_long)|uniprotkb:CG5920(orf name)|uniprotkb:Protein strings of pearls(gene name synonym)|uniprotkb:RpS2(gene name)|psi-mi:RpS2(display_short)|uniprotkb:sop(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108851|imex:IM-9552-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) refseq:NP_476874.1|flybase:FBgn0004867|refseq:NP_001285785.1|refseq:NP_001260303.1|dip:DIP-18767N|ensemblmetazoa:FBgn0004867(gene)|ensemblmetazoa:FBtr0079905(transcript)|ensemblmetazoa:FBtr0330682(transcript)|ensemblmetazoa:FBtr0345436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0048477"(oogenesis)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-3214858|reactome:R-DME-6791226|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-8876725|reactome:R-DME-975956|reactome:R-DME-975957 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 rogid:pJQkpqwmeYoJjSWX1kpO0yMZJrg7227 intact-crc:88092C88138A6C7B|rigid:8A4srBKZi2znwBs2Q7vsDpi09v4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K1Q7 uniprotkb:Q9VTL6 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 intact:EBI-2108861|ensemblmetazoa:FBpp0075838|ensemblmetazoa:FBpp0303920 psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:q9vtl6_drome(display_long)|uniprotkb:Polr3H(gene name)|psi-mi:Polr3H(display_short)|uniprotkb:Dmel\CG7339(gene name synonym)|uniprotkb:lincRNA.S4825(gene name synonym)|uniprotkb:CG7339(orf name)|uniprotkb:Dmel_CG7339(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108864|imex:IM-9552-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 refseq:NP_648490.1|flybase:FBgn0036188|refseq:NP_001261720.1|ensemblmetazoa:FBgn0036188(gene)|ensemblmetazoa:FBtr0076107(transcript)|ensemblmetazoa:FBtr0331530(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013238(RNA polymerase III, subunit Rpc25)|interpro:IPR036898|reactome:R-DME-76061|reactome:R-DME-76066 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 rogid:fbYiEsrBL8ujtAVTPVQXPeAMRms7227 intact-crc:5381AEC681421FE9|rigid:O5+mGpqfV/MvvXm+hyGJIBmUdOs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q86NZ5 uniprotkb:Q7K1Q7 intact:EBI-2108877|ensemblmetazoa:FBpp0075630 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 psi-mi:q86nz5_drome(display_long)|uniprotkb:Adk2(gene name)|psi-mi:Adk2(display_short)|uniprotkb:AdenoK(gene name synonym)|uniprotkb:CG11255(orf name) psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108880|imex:IM-9552-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0036337|ensemblmetazoa:FBgn0036337(gene)|ensemblmetazoa:FBtr0075896(transcript)|go:"GO:0004001"(adenosine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0044209"(AMP salvage)|interpro:IPR001805(Adenosine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056 refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:BckVO3R4s6Dak7eTLqxtkb2XpFI7227 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 intact-crc:53FFAF74C2E44922|rigid:uIXXYRmjWVUmiK0dAMBYCLqjdIA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VHU1 uniprotkb:Q7K1Q7 intact:EBI-2108869|ensemblmetazoa:FBpp0081355 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 psi-mi:ddx55_drome(display_long)|uniprotkb:CG9630(orf name) psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108872|imex:IM-9552-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649777.1|flybase:FBgn0037561|ensemblmetazoa:FBgn0037561(gene)|ensemblmetazoa:FBtr0081866(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417 refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fe2Mvxqfx49xTpnXeM2syc+ZwIQ7227 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 intact-crc:70002EDAE023C278|rigid:yr8Dh5lM06lPzfqtBimbUuE2UBs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNI9 uniprotkb:Q23983 intact:EBI-192627|ensemblmetazoa:FBpp0078315|ensemblmetazoa:FBpp0310534 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:q9vni9_drome(display_long)|uniprotkb:Sec20(gene name)|psi-mi:Sec20(display_short)|uniprotkb:Cg2023(gene name synonym)|uniprotkb:Dmel\CG2023(gene name synonym)|uniprotkb:lincRNA.683(gene name synonym)|uniprotkb:CG2023(orf name)|uniprotkb:Dmel_CG2023(orf name) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108885|imex:IM-9552-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649595.1|flybase:FBgn0037383|refseq:NP_001287187.1|ensemblmetazoa:FBgn0037383(gene)|ensemblmetazoa:FBtr0078666(transcript)|ensemblmetazoa:FBtr0344117(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031201"(SNARE complex)|interpro:IPR005606(Sec20)|reactome:R-DME-6811434 refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:K1Gej8zNJymHjNY3DKckx7zLRZg7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:2EB23B170F59D546|rigid:WhPNkGXDS6ngP9o0tmj1kkVg7Mc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31007 uniprotkb:Q8IGY2 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-2108890 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:q8igy2_drome(display_long)|uniprotkb:CG4370(orf name)|uniprotkb:Irk2(gene name)|psi-mi:Irk2(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108894|imex:IM-9552-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N flybase:FBgn0039081|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035220"(wing disc development)|go:"GO:0042391"(regulation of membrane potential)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:BTdXuEWd1xaRNi0WxsAqmx/9QR07227 intact-crc:DB8B0F359D69320C|rigid:KrGOlwXlFobncL+mLq6iNcVDQhU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P18053 uniprotkb:Q9XYN7 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108904|imex:IM-9552-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:964D7EBDFA71C749|rigid:922uI0Fh1Lulkbwz5nYoUgYXKTs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:Q9XYN7 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108899|imex:IM-9552-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:B33C5549806DC940|rigid:c4ZkOvy+k84WMauSOtyFhKqP/kA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9XYN7 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108914|imex:IM-9552-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:8F18322DD287962E|rigid:nvrmglfbeu1u+DIvwlkNb4rPUAY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K148 uniprotkb:Q9XYN7 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108909|imex:IM-9552-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:D4FEAE2EEAB1C8DC|rigid:JWOU7ESFEU0vnEk+myY9JCy08AQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG96 uniprotkb:Q8SXQ9 intact:EBI-117276|uniprotkb:Q541F8|uniprotkb:Q9TX90|ensemblmetazoa:FBpp0082043 intact:EBI-2108833|uniprotkb:Q9VG90|ensemblmetazoa:FBpp0082048 psi-mi:gstd4_drome(display_long)|uniprotkb:GstD4(gene name)|psi-mi:GstD4(display_short)|uniprotkb:gstD23(gene name synonym)|uniprotkb:CG11512(orf name)|uniprotkb:GSTD4-4(gene name synonym) psi-mi:q8sxq9_drome(display_long)|uniprotkb:CG17639(orf name)|uniprotkb:GstD11(gene name)|psi-mi:GstD11(display_short)|uniprotkb:cg17639(gene name synonym)|uniprotkb:"BcDNA:RE72392"(gene name synonym)|uniprotkb:DmGSTD11(gene name synonym)|uniprotkb:Dmel\CG17639(gene name synonym)|uniprotkb:GSTD11(gene name synonym)|uniprotkb:gstd11(gene name synonym)|uniprotkb:Dmel_CG17639(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108919|imex:IM-9552-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010040(gene)|ensemblmetazoa:FBtr0082571(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|refseq:NP_524913.1|flybase:FBgn0010040|dip:DIP-19902N refseq:NP_650183.1|flybase:FBgn0038029|ensemblmetazoa:FBgn0038029(gene)|ensemblmetazoa:FBtr0082576(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WnxIOP1ON8XMcxemAdfgL9YKN2I7227 rogid:U5SnuNlvbNONohNCTTAPPKRIq607227 intact-crc:CCDA3308AC57C825|rigid:xkfPwQjRHnwY8tK4KHXYHxIsCSs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JVZ8 uniprotkb:Q8SXQ9 intact:EBI-2108924|ensemblmetazoa:FBpp0085876|ensemblmetazoa:FBpp0311692 intact:EBI-2108833|uniprotkb:Q9VG90|ensemblmetazoa:FBpp0082048 psi-mi:q7jvz8_drome(display_long)|uniprotkb:GstE11(gene name)|psi-mi:GstE11(display_short)|uniprotkb:Dmel\CG5224(gene name synonym)|uniprotkb:GSTE11(gene name synonym)|uniprotkb:cg5224(gene name synonym)|uniprotkb:gste11(gene name synonym)|uniprotkb:CG5224(orf name)|uniprotkb:Dmel_CG5224(orf name) psi-mi:q8sxq9_drome(display_long)|uniprotkb:CG17639(orf name)|uniprotkb:GstD11(gene name)|psi-mi:GstD11(display_short)|uniprotkb:cg17639(gene name synonym)|uniprotkb:"BcDNA:RE72392"(gene name synonym)|uniprotkb:DmGSTD11(gene name synonym)|uniprotkb:Dmel\CG17639(gene name synonym)|uniprotkb:GSTD11(gene name synonym)|uniprotkb:gstd11(gene name synonym)|uniprotkb:Dmel_CG17639(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108928|imex:IM-9552-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611339.1|flybase:FBgn0034354|refseq:NP_001286575.1|ensemblmetazoa:FBgn0034354(gene)|ensemblmetazoa:FBtr0086697(transcript)|ensemblmetazoa:FBtr0345628(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282 refseq:NP_650183.1|flybase:FBgn0038029|ensemblmetazoa:FBgn0038029(gene)|ensemblmetazoa:FBtr0082576(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:c0uFuA7AKzj/F4uJyV7iu2L2iqQ7227 rogid:U5SnuNlvbNONohNCTTAPPKRIq607227 intact-crc:0B7326F84B47B04A|rigid:9XJGA93sGF/u6mOtOZxpndvAqdg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VH66 uniprotkb:Q7JWS8 intact:EBI-184344|ensemblmetazoa:FBpp0081617|ensemblmetazoa:FBpp0312544 intact:EBI-74904|intact:EBI-2108936|ensemblmetazoa:FBpp0084561|ensemblmetazoa:FBpp0084562|ensemblmetazoa:FBpp0084563 psi-mi:q9vh66_drome(display_long)|uniprotkb:Dmel\CG8500(gene name)|psi-mi:Dmel\CG8500(display_short)|uniprotkb:CG8500-RA(gene name synonym)|uniprotkb:Q9VH66(gene name synonym)|uniprotkb:CG8500(orf name)|uniprotkb:Dmel_CG8500(orf name) psi-mi:q7jws8_drome(display_long)|uniprotkb:Mtl(gene name)|psi-mi:Mtl(display_short)|uniprotkb:5588(gene name synonym)|uniprotkb:Dmel\CG5588(gene name synonym)|uniprotkb:MTL(gene name synonym)|uniprotkb:Mig2-like(gene name synonym)|uniprotkb:Mt1(gene name synonym)|uniprotkb:Rac(gene name synonym)|uniprotkb:Rac GTPase(gene name synonym)|uniprotkb:Rac-like(gene name synonym)|uniprotkb:dMig-2(gene name synonym)|uniprotkb:mtl(gene name synonym)|uniprotkb:Dmel_CG5588(orf name)|uniprotkb:CG5588(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108933|imex:IM-9552-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649948.1|flybase:FBgn0037754|refseq:NP_001303452.1|ensemblmetazoa:FBtr0082139(transcript)|ensemblmetazoa:FBtr0347364(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|ensemblmetazoa:FBgn0037754(gene) refseq:NP_524533.1|refseq:NP_733222.1|refseq:NP_733223.1|flybase:FBgn0039532|ensemblmetazoa:FBgn0039532(gene)|ensemblmetazoa:FBtr0085191(transcript)|ensemblmetazoa:FBtr0085192(transcript)|ensemblmetazoa:FBtr0085193(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007254"(JNK cascade)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035099"(hemocyte migration)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nazv4Xl/PZzCBZnusM0GXlaqBEE7227 rogid:x5LZmisdfK+Fu3EyxmAzuYFzMSQ7227 intact-crc:8BDD184ED61E7D21|rigid:uPwff2KnAwpAK4ugaA071nqG7ks false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXW3 uniprotkb:Q9VT75 intact:EBI-166026|ensemblmetazoa:FBpp0073835|uniprotkb:Q960Y1 intact:EBI-133584|ensemblmetazoa:FBpp0076077|ensemblmetazoa:FBpp0076078|ensemblmetazoa:FBpp0076079|ensemblmetazoa:FBpp0076080|ensemblmetazoa:FBpp0076081 psi-mi:q9vxw3_drome(display_long)|uniprotkb:Dmel\CG12608(gene name)|psi-mi:Dmel\CG12608(display_short)|uniprotkb:CG12608(orf name)|uniprotkb:Dmel_CG12608(orf name) psi-mi:q9vt75_drome(display_long)|uniprotkb:vnc(gene name)|psi-mi:vnc(display_short)|uniprotkb:Ard1(gene name synonym)|uniprotkb:ARD1(gene name synonym)|uniprotkb:DmAAF50178(gene name synonym)|uniprotkb:Dmel\CG11989(gene name synonym)|uniprotkb:NAA10(gene name synonym)|uniprotkb:Naa10(gene name synonym)|uniprotkb:ard1(gene name synonym)|uniprotkb:dArd1(gene name synonym)|uniprotkb:"l(3)67BDk"(gene name synonym)|uniprotkb:Dmel_CG11989(orf name)|uniprotkb:11(gene name synonym)|uniprotkb:dNaa10(gene name synonym)|uniprotkb:CG11989(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108942|imex:IM-9552-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0074018(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|ensemblmetazoa:FBgn0030630(gene)|refseq:NP_573019.1|flybase:FBgn0030630 refseq:NP_648378.1|refseq:NP_729581.1|refseq:NP_729582.1|refseq:NP_729583.1|refseq:NP_729584.1|flybase:FBgn0263251|ensemblmetazoa:FBgn0263251(gene)|ensemblmetazoa:FBtr0076348(transcript)|ensemblmetazoa:FBtr0076349(transcript)|ensemblmetazoa:FBtr0076350(transcript)|ensemblmetazoa:FBtr0076351(transcript)|ensemblmetazoa:FBtr0076352(transcript)|go:"GO:0016573"(histone acetylation)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031248"(protein acetyltransferase complex)|go:"GO:0031415"(NatA complex)|go:"GO:0048477"(oogenesis)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cnH75G6LB7REYv2Sa/ySy1JROho7227 rogid:o3xmQfTimj+I6AK4peQ6/M6eaXU7227 intact-crc:EA946F28B6432D39|rigid:qY2stOLKsvEofD+MVrwBrP4P4Sw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18332 uniprotkb:Q9VK46 intact:EBI-89408|ensemblmetazoa:FBpp0083503 intact:EBI-182760|intact:EBI-1630152|ensemblmetazoa:FBpp0080011 psi-mi:o18332_drome(display_long)|uniprotkb:Rab1(gene name)|psi-mi:Rab1(display_short)|uniprotkb:Rab1-RA(gene name synonym)|uniprotkb:CG3320(orf name)|uniprotkb:AAF55873(gene name synonym)|uniprotkb:DRAB1(gene name synonym)|uniprotkb:DRab1(gene name synonym)|uniprotkb:Dm Rab1(gene name synonym)|uniprotkb:DmRab1(gene name synonym)|uniprotkb:Dmel\CG3320(gene name synonym)|uniprotkb:O18332(gene name synonym)|uniprotkb:RAB1a(gene name synonym)|uniprotkb:Rab1a(gene name synonym)|uniprotkb:dRab1(gene name synonym)|uniprotkb:dar6(gene name synonym)|uniprotkb:drab1(gene name synonym)|uniprotkb:rab1(gene name synonym)|uniprotkb:Dmel_CG3320(orf name)|uniprotkb:Dar6(gene name synonym)|uniprotkb:omt(gene name synonym) psi-mi:q9vk46_drome(display_long)|uniprotkb:Yip1d1(gene name)|psi-mi:Yip1d1(display_short)|uniprotkb:Dmel\CG12404(gene name synonym)|uniprotkb:Yip1(gene name synonym)|uniprotkb:CG12404(orf name)|uniprotkb:Dmel_CG12404(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108947|imex:IM-9552-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009306"(protein secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0005525"(GTP binding)|ensemblmetazoa:FBgn0285937(gene)|ensemblmetazoa:FBtr0084104(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0140164"(Golgi transport complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1905808"(positive regulation of synapse pruning)|go:"GO:0034067"(protein localization to Golgi apparatus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-162658|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-8873719|reactome:R-DME-8876198|refseq:NP_732610.1|dip:DIP-51950N|flybase:FBgn0285937 refseq:NP_609596.1|flybase:FBgn0032465|dip:DIP-18836N|ensemblmetazoa:FBgn0032465(gene)|ensemblmetazoa:FBtr0080430(transcript)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1905808"(positive regulation of synapse pruning)|interpro:IPR006977(Yip1 domain) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:erR2ZZsEjZGk3sP5k09kQNV9mQo7227 rogid:JiFe0mxiBay45DuS8UjWtWVUwGw7227 intact-crc:35667F2146A06CC5|rigid:APSTrMGSZadV4YPoPW3nr2g/FLs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VZC9 uniprotkb:O18332 intact:EBI-2108952|ensemblmetazoa:FBpp0073149 intact:EBI-89408|ensemblmetazoa:FBpp0083503 psi-mi:q9vzc9_drome(display_long)|uniprotkb:Syx17(gene name)|psi-mi:Syx17(display_short)|uniprotkb:Dm Syx17(gene name synonym)|uniprotkb:DmSyx17(gene name synonym)|uniprotkb:Dmel\CG7452(gene name synonym)|uniprotkb:S17(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:syx17(gene name synonym)|uniprotkb:CG7452(orf name)|uniprotkb:Dmel_CG7452(orf name)|uniprotkb:Stx17(gene name synonym) psi-mi:o18332_drome(display_long)|uniprotkb:Rab1(gene name)|psi-mi:Rab1(display_short)|uniprotkb:Rab1-RA(gene name synonym)|uniprotkb:CG3320(orf name)|uniprotkb:AAF55873(gene name synonym)|uniprotkb:DRAB1(gene name synonym)|uniprotkb:DRab1(gene name synonym)|uniprotkb:Dm Rab1(gene name synonym)|uniprotkb:DmRab1(gene name synonym)|uniprotkb:Dmel\CG3320(gene name synonym)|uniprotkb:O18332(gene name synonym)|uniprotkb:RAB1a(gene name synonym)|uniprotkb:Rab1a(gene name synonym)|uniprotkb:dRab1(gene name synonym)|uniprotkb:dar6(gene name synonym)|uniprotkb:drab1(gene name synonym)|uniprotkb:rab1(gene name synonym)|uniprotkb:Dmel_CG3320(orf name)|uniprotkb:Dar6(gene name synonym)|uniprotkb:omt(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108956|imex:IM-9552-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523926.1|flybase:FBgn0035540|ensemblmetazoa:FBgn0035540(gene)|ensemblmetazoa:FBtr0073293(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR010989(t-SNARE)|interpro:IPR028676 go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009306"(protein secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0005525"(GTP binding)|ensemblmetazoa:FBgn0285937(gene)|ensemblmetazoa:FBtr0084104(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0140164"(Golgi transport complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1905808"(positive regulation of synapse pruning)|go:"GO:0034067"(protein localization to Golgi apparatus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-162658|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-8873719|reactome:R-DME-8876198|refseq:NP_732610.1|dip:DIP-51950N|flybase:FBgn0285937 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:AVwCimBFmfW0aitbEjEpGIjqZWA7227 rogid:erR2ZZsEjZGk3sP5k09kQNV9mQo7227 intact-crc:38F9A738E849461E|rigid:j+pE0NTS5LTAzwOGhe/vaOuacrs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VEB3 uniprotkb:Q9V9Z9 intact:EBI-2108961|uniprotkb:Q95U84|ensemblmetazoa:FBpp0082984 intact:EBI-243148|ensemblmetazoa:FBpp0085119 psi-mi:rpf2_drome(display_long)|uniprotkb:Non3(gene name)|psi-mi:Non3(display_short)|uniprotkb:Brix domain-containing protein 1 homolog(gene name synonym)|uniprotkb:Novel nucleolar protein 3(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:CG7993(orf name) psi-mi:ebp2_drome(display_long)|uniprotkb:CG1542(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108965|imex:IM-9552-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650694.2|flybase:FBgn0038585|ensemblmetazoa:FBgn0038585(gene)|ensemblmetazoa:FBtr0083562(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0019843"(rRNA binding)|go:"GO:0051301"(cell division)|interpro:IPR007109(Brix)|interpro:IPR039770 refseq:NP_651850.1|flybase:FBgn0039828|dip:DIP-22231N|ensemblmetazoa:FBgn0039828(gene)|ensemblmetazoa:FBtr0085757(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|reactome:R-DME-6791226 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:m5IK0IyRlNg7HALJqLpshA746xM7227 rogid:KTxVk9p9HcvLKnvyMgojGdNfLak7227 intact-crc:0524FB29816CA8AF|rigid:uzH0pmy9qMAeB4lHjcj5p5pB0Tw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KNC5 uniprotkb:Q9W3D5 intact:EBI-2108970|ensemblmetazoa:FBpp0110232 intact:EBI-93497|ensemblmetazoa:FBpp0071164|ensemblmetazoa:FBpp0304872 psi-mi:q7knc5_drome(display_long)|uniprotkb:CG32464(orf name)|uniprotkb:CG10196(gene name synonym)|uniprotkb:CG10199(gene name synonym)|uniprotkb:mtd(gene name)|psi-mi:mtd(display_short)|uniprotkb:L82(gene name synonym)|uniprotkb:"l(3)82Fd"(gene name synonym)|uniprotkb:Dmel_CG32464(orf name)|uniprotkb:Dmel\CG32464(gene name synonym)|uniprotkb:"L(3)82Fd"(gene name synonym)|uniprotkb:"anon-EST:Posey263"(gene name synonym)|uniprotkb:"l(3)82FD"(gene name synonym) psi-mi:q9w3d5_drome(display_long)|uniprotkb:Dmel\CG12081(gene name)|psi-mi:Dmel\CG12081(display_short)|uniprotkb:Dmel_CG12081(orf name)|uniprotkb:CG12081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108976|imex:IM-9552-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036679.1|flybase:FBgn0013576|ensemblmetazoa:FBgn0013576(gene)|ensemblmetazoa:FBtr0110932(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR006571(TLDc)|interpro:IPR018392|interpro:IPR036779 refseq:NP_572494.1|flybase:FBgn0030053|ensemblmetazoa:FBgn0030053(gene)|ensemblmetazoa:FBtr0071218(transcript)|ensemblmetazoa:FBtr0332626(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_001259343.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:OwtqNo61x2qz3BXJOA5OLwKJ6LA7227 rogid:EnlZwkhBefjihcoP38MYy/OhhvE7227 intact-crc:ABDCB2C1277D3E84|rigid:/f88KiEie565XK0sFkHoW+mHAI8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K0X9 uniprotkb:Q23983 intact:EBI-167209|ensemblmetazoa:FBpp0078007|ensemblmetazoa:FBpp0078008|intact:EBI-2108484 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:q7k0x9_drome(display_long)|uniprotkb:Syx7(gene name)|psi-mi:Syx7(display_short)|uniprotkb:Aval(gene name synonym)|uniprotkb:Avl(gene name synonym)|uniprotkb:Dm Syx7(gene name synonym)|uniprotkb:DmSyx7(gene name synonym)|uniprotkb:Dmel\CG5081(gene name synonym)|uniprotkb:FCP-C(gene name synonym)|uniprotkb:SYX7(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:avl(gene name synonym)|uniprotkb:braided(gene name synonym)|uniprotkb:dSyn7(gene name synonym)|uniprotkb:syx7(gene name synonym)|uniprotkb:Dmel_CG5081(orf name)|uniprotkb:CG5081(orf name)|uniprotkb:STX7(gene name synonym) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108981|imex:IM-9552-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730632.1|refseq:NP_730633.1|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)|ensemblmetazoa:FBgn0267849(gene)|ensemblmetazoa:FBtr0078351(transcript)|ensemblmetazoa:FBtr0078352(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0035073"(pupariation)|flybase:FBgn0267849 refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:i9SFYgLkPP0m5p7BT00RJV6JT/c7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:2B152EFA17702CC9|rigid:E1xk/+QVlUkyAdDnfvHect9VdGo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q94920 uniprotkb:P84029 intact:EBI-184763|intact:EBI-1631556|uniprotkb:Q94997|uniprotkb:Q9VKP1|uniprotkb:Q29QZ3|ensemblmetazoa:FBpp0079771|ensemblmetazoa:FBpp0079772|ensemblmetazoa:FBpp0100039|ensemblmetazoa:FBpp0293784|ensemblmetazoa:FBpp0304343 intact:EBI-85896|uniprotkb:P00033|uniprotkb:Q9VJJ3|uniprotkb:P00034|ensemblmetazoa:FBpp0080446|ensemblmetazoa:FBpp0311164 psi-mi:vdac_drome(display_long)|uniprotkb:porin(gene name)|psi-mi:porin(display_short)|uniprotkb:POR-1(gene name synonym)|uniprotkb:VDAC(gene name synonym)|uniprotkb:CG6647(orf name)|uniprotkb:Porin(gene name synonym)|uniprotkb:DmVDAC(gene name synonym) psi-mi:cyc2_drome(display_long)|uniprotkb:Cyt-c-p(gene name)|psi-mi:Cyt-c-p(display_short)|uniprotkb:CYTC2(gene name synonym)|uniprotkb:DC4(gene name synonym)|uniprotkb:CG17903(orf name)|uniprotkb:Cytochrome c-proximal(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108986|imex:IM-9552-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033899.1|refseq:NP_476813.1|refseq:NP_599110.1|flybase:FBgn0004363|refseq:NP_001245961.1|refseq:NP_001260365.1|dip:DIP-17501N|ensemblmetazoa:FBgn0004363(gene)|ensemblmetazoa:FBtr0080182(transcript)|ensemblmetazoa:FBtr0080183(transcript)|ensemblmetazoa:FBtr0100584(transcript)|ensemblmetazoa:FBtr0305260(transcript)|ensemblmetazoa:FBtr0332029(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006811"(ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007291"(sperm individualization)|go:"GO:0007602"(phototransduction)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0016006"(Nebenkern)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046930"(pore complex)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|reactome:R-DME-5205685|reactome:R-DME-70268 refseq:NP_477176.1|ensemblmetazoa:FBgn0284248(gene)|ensemblmetazoa:FBtr0080889(transcript)|ensemblmetazoa:FBtr0344849(transcript)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|reactome:R-DME-111457|reactome:R-DME-3299685|reactome:R-DME-5620971|reactome:R-DME-5628897|reactome:R-DME-611105|reactome:R-DME-9707564|go:"GO:0046872"(metal ion binding)|refseq:NP_001285984.1|flybase:FBgn0284248 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:BzqX5C247xgqsKNPYtJxwti1ul07227 rogid:4zv8LiqC9WMl9EBPeDZzUWtTkqw7227 intact-crc:F44B3400013C162B|rigid:6c8yuSvQnlz9lZ8oE29xU0uL69E false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P19018-1 uniprotkb:P26686 intact:EBI-198437|ensemblmetazoa:FBpp0088562|ensemblmetazoa:FBpp0088946|ensemblmetazoa:FBpp0088947 intact:EBI-133905|uniprotkb:Q24252|uniprotkb:Q26277|uniprotkb:Q8IH12|uniprotkb:Q8ING7|uniprotkb:Q8ING8|uniprotkb:Q8ING9|uniprotkb:Q8MZ66|uniprotkb:Q8T0I0|uniprotkb:Q9VFT0|uniprotkb:Q9VFT1|uniprotkb:A4V2U2|uniprotkb:E1JIK1|uniprotkb:E1JIK2|uniprotkb:E1JIK3|uniprotkb:E4NKI6 psi-mi:p19018-1(display_long)|uniprotkb:Major(isoform synonym)|uniprotkb:A(isoform synonym)|uniprotkb:Mattox-A(isoform synonym)|uniprotkb:F(isoform synonym)|uniprotkb:G(isoform synonym)|uniprotkb:tra2(gene name)|psi-mi:tra2(display_short)|uniprotkb:tra-2(gene name synonym)|uniprotkb:CG10128(orf name) psi-mi:srr55_drome(display_long)|uniprotkb:B52(gene name)|psi-mi:B52(display_short)|uniprotkb:CG10851(orf name)|uniprotkb:Protein enhancer of deformed(gene name synonym)|uniprotkb:52 kDa bracketing protein(gene name synonym)|uniprotkb:B52 protein(gene name synonym)|uniprotkb:"E(Dfd)"(gene name synonym)|uniprotkb:RS55(gene name synonym)|uniprotkb:SR55(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108991|imex:IM-9552-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-198424(tra2_drome)|ensemblmetazoa:FBgn0003742(gene)|ensemblmetazoa:FBtr0089617(transcript)|ensemblmetazoa:FBtr0089620(transcript)|ensemblmetazoa:FBtr0089621(transcript) refseq:NP_001163603.1|refseq:NP_001163604.1|refseq:NP_788665.1|refseq:NP_788666.1|refseq:NP_788668.1|refseq:NP_788669.1|refseq:NP_788670.1|flybase:FBgn0004587|refseq:NP_001014619.2|refseq:NP_788667.2|refseq:NP_788671.2|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0044819"(mitotic G1/S transition checkpoint signaling)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051607"(defense response to virus)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uL8i3jhKpNlSUIxgCb/9lb1L/1E7227 rogid:W93o6QSYDl81WHhwaxV+WaOxo+c7227 intact-crc:6D18DED18A45BCE9|rigid:l/Z834TAX7LkCOVVViWHS3Aau3M false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JYK2 uniprotkb:Q8MR16 intact:EBI-2109017|ensemblmetazoa:FBpp0088001|ensemblmetazoa:FBpp0308259|ensemblmetazoa:FBpp0308260|ensemblmetazoa:FBpp0308261 intact:EBI-2109013|ensemblmetazoa:FBpp0079466 psi-mi:q7jyk2_drome(display_long)|uniprotkb:Dmel\CG1941(gene name)|psi-mi:Dmel\CG1941(display_short)|uniprotkb:CG1941(orf name)|uniprotkb:Dmel_CG1941(orf name) psi-mi:q8mr16_drome(display_long)|uniprotkb:CG4036(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109010|imex:IM-9552-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610317.1|flybase:FBgn0033214|refseq:NP_001286161.1|refseq:NP_001286162.1|refseq:NP_001286163.1|ensemblmetazoa:FBgn0033214(gene)|ensemblmetazoa:FBtr0088927(transcript)|ensemblmetazoa:FBtr0339114(transcript)|ensemblmetazoa:FBtr0339115(transcript)|ensemblmetazoa:FBtr0339116(transcript)|go:"GO:0004144"(diacylglycerol O-acyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|interpro:IPR007130(Diacylglycerol acyltransferase)|reactome:R-DME-1482883|reactome:R-DME-2142753|reactome:R-DME-2187335|reactome:R-DME-75109|reactome:R-DME-9640463 flybase:FBgn0032149|ensemblmetazoa:FBgn0032149(gene)|ensemblmetazoa:FBtr0079870(transcript)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032451"(demethylase activity)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0070989"(oxidative demethylation)|interpro:IPR032857 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:2WjIUU2UDR42IgG3POpq6kwXxHU7227 rogid:rN8GyI/i2wyDr9uVlYntTXASEqY7227 intact-crc:6646EB6D42FBC159|rigid:8ahS33yCxRXXirax7PTgAUqODIg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9Y171 uniprotkb:Q0E924 intact:EBI-2109004|uniprotkb:Q9VTC5|ensemblmetazoa:FBpp0076000|ensemblmetazoa:FBpp0076001 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 psi-mi:q9y171_drome(display_long)|uniprotkb:OXA1L(gene name)|psi-mi:OXA1L(display_short)|uniprotkb:BcDNA.GH02220(gene name synonym)|uniprotkb:"BcDNA:GH02220"(gene name synonym)|uniprotkb:Dmel\CG6404(gene name synonym)|uniprotkb:OXA1(gene name synonym)|uniprotkb:CG6404(orf name)|uniprotkb:Dmel_CG6404(orf name) psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109001|imex:IM-9552-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648417.1|refseq:NP_729634.1|flybase:FBgn0027615|ensemblmetazoa:FBgn0027615(gene)|ensemblmetazoa:FBtr0076271(transcript)|ensemblmetazoa:FBtr0076272(transcript)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032977"(membrane insertase activity)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0097002"(mitochondrial inner boundary membrane)|interpro:IPR001708(60 kDa inner membrane insertion protein)|interpro:IPR028055|reactome:R-DME-5389840|reactome:R-DME-5419276 refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:B6PJtBz6xEeDD4KnFrDQr1f/7WU7227 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 intact-crc:E4AAD0C5B14CF1AD|rigid:yjhLOEYFDH9JHzwhVNZL0hb8eAk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48462 uniprotkb:P09491 intact:EBI-869621|uniprotkb:Q9W2V5|ensemblmetazoa:FBpp0071382|ensemblmetazoa:FBpp0305497 intact:EBI-233791|uniprotkb:P09490|uniprotkb:Q24408|uniprotkb:Q24427|uniprotkb:Q24428|uniprotkb:Q8SZ65|uniprotkb:Q9VF95|uniprotkb:A0AVW5|uniprotkb:A4V2Y6|ensemblmetazoa:FBpp0089270 psi-mi:pp1b_drome(display_long)|uniprotkb:Protein flap wing(gene name synonym)|uniprotkb:flw(gene name)|psi-mi:flw(display_short)|uniprotkb:PP1-9C(gene name synonym)|uniprotkb:PP1-BETA-9C(gene name synonym)|uniprotkb:CG2096(orf name) psi-mi:tpm2_drome(display_long)|uniprotkb:Tm2(gene name)|psi-mi:Tm2(display_short)|uniprotkb:TmI(gene name synonym)|uniprotkb:CG4843(orf name)|uniprotkb:Tropomyosin I(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2108996|imex:IM-9552-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524738.1|flybase:FBgn0000711|refseq:NP_001259407.1|ensemblmetazoa:FBgn0000711(gene)|ensemblmetazoa:FBtr0071447(transcript)|ensemblmetazoa:FBtr0333305(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1905330"(regulation of morphogenesis of an epithelium)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|reactome:R-DME-2565942|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|reactome:R-DME-5625740|reactome:R-DME-5627123 refseq:NP_524361.4|refseq:NP_732012.1|refseq:NP_732013.2|flybase:FBgn0004117|refseq:NP_001287337.1|refseq:NP_001262592.1|refseq:NP_001262593.1|dip:DIP-21556N|ensemblmetazoa:FBgn0004117(gene)|ensemblmetazoa:FBtr0083080(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007507"(heart development)|go:"GO:0051015"(actin filament binding)|go:"GO:0060298"(positive regulation of sarcomere organization)|interpro:IPR000533(Tropomyosin)|reactome:R-DME-9013424 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PZSfwmpwqFs81zLVfparcg1xIZY7227 rogid:U0ue0JykMFrmEJSiXLUGPRMvF9g7227 intact-crc:D930EA950DEF9B7C|rigid:PhgRDRO/9dNFJvkebGyu2wRv0us false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9Y162 uniprotkb:Q8SXB1 intact:EBI-161914|ensemblmetazoa:FBpp0074278|ensemblmetazoa:FBpp0309628 intact:EBI-2108683|ensemblmetazoa:FBpp0084340 psi-mi:q9y162_drome(display_long)|uniprotkb:Vps4(gene name)|psi-mi:Vps4(display_short)|uniprotkb:3B1(gene name synonym)|uniprotkb:"BcDNA:GH02678"(gene name synonym)|uniprotkb:DmBcDNA.GH02678(gene name synonym)|uniprotkb:Dmel\CG6842(gene name synonym)|uniprotkb:Dvps4(gene name synonym)|uniprotkb:Vps4B(gene name synonym)|uniprotkb:"bcDNA:GH02678"(gene name synonym)|uniprotkb:dvps4(gene name synonym)|uniprotkb:vps4(gene name synonym)|uniprotkb:Dmel_CG6842(orf name)|uniprotkb:BcDNA.GH02678(gene name synonym)|uniprotkb:CG6842(orf name) psi-mi:q8sxb1_drome(display_long)|uniprotkb:Vps2(gene name)|psi-mi:Vps2(display_short)|uniprotkb:vps2(gene name synonym)|uniprotkb:CG14542(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109022|imex:IM-9552-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573258.1|ensemblmetazoa:FBgn0283469(gene)|ensemblmetazoa:FBtr0074504(transcript)|ensemblmetazoa:FBtr0342787(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0007033"(vacuole organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045463"(R8 cell development)|go:"GO:0045470"(R8 cell-mediated photoreceptor organization)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR031255|interpro:IPR036181|interpro:IPR041569|reactome:R-DME-9668328|refseq:NP_001285396.1|flybase:FBgn0283469 flybase:FBgn0039402|ensemblmetazoa:FBgn0039402(gene)|ensemblmetazoa:FBtr0084967(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR005024(Snf7) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ztNVeFtIOGStdx60lDjss+ONTrs7227 rogid:539QTjLR85Yu+kvkcKUPlGhvjYg7227 intact-crc:BA29C2D9C1D1344A|rigid:bexaWXLUMIgAzX2WNeOOcnihd2k false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG96 uniprotkb:Q7JVI6 intact:EBI-117276|uniprotkb:Q541F8|uniprotkb:Q9TX90|ensemblmetazoa:FBpp0082043 intact:EBI-2109035|ensemblmetazoa:FBpp0087660|ensemblmetazoa:FBpp0291657 psi-mi:gstd4_drome(display_long)|uniprotkb:GstD4(gene name)|psi-mi:GstD4(display_short)|uniprotkb:gstD23(gene name synonym)|uniprotkb:CG11512(orf name)|uniprotkb:GSTD4-4(gene name synonym) psi-mi:q7jvi6_drome(display_long)|uniprotkb:GstE13(gene name)|psi-mi:GstE13(display_short)|uniprotkb:"BcDNA:LD22317"(gene name synonym)|uniprotkb:Dmel\CG11784(gene name synonym)|uniprotkb:GSTE13(gene name synonym)|uniprotkb:gste13(gene name synonym)|uniprotkb:CG11784(orf name)|uniprotkb:Dmel_CG11784(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109032|imex:IM-9552-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010040(gene)|ensemblmetazoa:FBtr0082571(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|refseq:NP_524913.1|flybase:FBgn0010040|dip:DIP-19902N refseq:NP_001188889.1|refseq:NP_610457.1|flybase:FBgn0033381|ensemblmetazoa:FBgn0033381(gene)|ensemblmetazoa:FBtr0088579(transcript)|ensemblmetazoa:FBtr0302495(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WnxIOP1ON8XMcxemAdfgL9YKN2I7227 rogid:uCjDDbw7mQVUkmWCcJEcKEgfQEM7227 intact-crc:6C1DEE02D7D6D66B|rigid:8/oqTxFCxqfTWVeTHJbhZyG66+g false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JVZ8 uniprotkb:Q9VG96 intact:EBI-2108924|ensemblmetazoa:FBpp0085876|ensemblmetazoa:FBpp0311692 intact:EBI-117276|uniprotkb:Q541F8|uniprotkb:Q9TX90|ensemblmetazoa:FBpp0082043 psi-mi:q7jvz8_drome(display_long)|uniprotkb:GstE11(gene name)|psi-mi:GstE11(display_short)|uniprotkb:Dmel\CG5224(gene name synonym)|uniprotkb:GSTE11(gene name synonym)|uniprotkb:cg5224(gene name synonym)|uniprotkb:gste11(gene name synonym)|uniprotkb:CG5224(orf name)|uniprotkb:Dmel_CG5224(orf name) psi-mi:gstd4_drome(display_long)|uniprotkb:GstD4(gene name)|psi-mi:GstD4(display_short)|uniprotkb:gstD23(gene name synonym)|uniprotkb:CG11512(orf name)|uniprotkb:GSTD4-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109027|imex:IM-9552-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611339.1|flybase:FBgn0034354|refseq:NP_001286575.1|ensemblmetazoa:FBgn0034354(gene)|ensemblmetazoa:FBtr0086697(transcript)|ensemblmetazoa:FBtr0345628(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282 ensemblmetazoa:FBgn0010040(gene)|ensemblmetazoa:FBtr0082571(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|refseq:NP_524913.1|flybase:FBgn0010040|dip:DIP-19902N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:c0uFuA7AKzj/F4uJyV7iu2L2iqQ7227 rogid:WnxIOP1ON8XMcxemAdfgL9YKN2I7227 intact-crc:FB42737BE23FC681|rigid:6CsbXwAJ7LMsCN7eWd81TIOaMW0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG96 uniprotkb:Q9VG94 intact:EBI-117276|uniprotkb:Q541F8|uniprotkb:Q9TX90|ensemblmetazoa:FBpp0082043 intact:EBI-152218|uniprotkb:Q9TX93|ensemblmetazoa:FBpp0082045 psi-mi:gstd4_drome(display_long)|uniprotkb:GstD4(gene name)|psi-mi:GstD4(display_short)|uniprotkb:gstD23(gene name synonym)|uniprotkb:CG11512(orf name)|uniprotkb:GSTD4-4(gene name synonym) psi-mi:gstd6_drome(display_long)|uniprotkb:GstD6(gene name)|psi-mi:GstD6(display_short)|uniprotkb:gstD25(gene name synonym)|uniprotkb:CG4423(orf name)|uniprotkb:GSTD6-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109040|imex:IM-9552-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010040(gene)|ensemblmetazoa:FBtr0082571(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|refseq:NP_524913.1|flybase:FBgn0010040|dip:DIP-19902N refseq:NP_524915.1|flybase:FBgn0010042|ensemblmetazoa:FBgn0010042(gene)|ensemblmetazoa:FBtr0082573(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|dip:DIP-19904N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WnxIOP1ON8XMcxemAdfgL9YKN2I7227 rogid:yLMZqw8pFrpfCW23h/8ZasBuKYE7227 intact-crc:B03A03BED65EA219|rigid:XWuzMILOOMXH51COxqgyjjVU138 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IH02 uniprotkb:P12982 intact:EBI-2109045|ensemblmetazoa:FBpp0112342 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 psi-mi:q8ih02_drome(display_long)|uniprotkb:CG32264(orf name)|uniprotkb:CG10860(gene name)|psi-mi:CG10860(display_short) psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109049|imex:IM-9552-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0052264|ensemblmetazoa:FBgn0052264(gene)|ensemblmetazoa:FBtr0113430(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|interpro:IPR004018(RPEL repeat) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:aLrXZsmZQbbKBKh23YAPfHddBCc7227 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 intact-crc:D71F0069DF4CA8DB|rigid:aH1s0C6cSE5uDJNRoW/H1Z0R0R4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P42281 uniprotkb:Q9U616 intact:EBI-2109054|uniprotkb:A4V1K8|uniprotkb:Q9VS23|ensemblmetazoa:FBpp0076624|ensemblmetazoa:FBpp0076625 intact:EBI-181719|uniprotkb:Q9VP59|ensemblmetazoa:FBpp0078066 psi-mi:acbp_drome(display_long)|uniprotkb:Acbp2(gene name)|psi-mi:Acbp2(display_short)|uniprotkb:Dbi(gene name synonym)|uniprotkb:Diazepam-binding inhibitor homolog(gene name synonym)|uniprotkb:CG8627(orf name) psi-mi:gcsh_drome(display_long)|uniprotkb:ppl(gene name)|psi-mi:ppl(display_short)|uniprotkb:CG7758(orf name)|uniprotkb:Protein pumpless(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109059|imex:IM-9552-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523952.2|refseq:NP_729218.1|flybase:FBgn0010387|ensemblmetazoa:FBgn0010387(gene)|ensemblmetazoa:FBtr0076915(transcript)|ensemblmetazoa:FBtr0076916(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042049"(cellular acyl-CoA homeostasis)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984 refseq:NP_524197.1|flybase:FBgn0027945|dip:DIP-19395N|ensemblmetazoa:FBgn0027945(gene)|ensemblmetazoa:FBtr0078412(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR002930(Glycine cleavage H-protein)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR011053(Single hybrid motif)|interpro:IPR017453(Glycine cleavage H-protein, subgroup)|interpro:IPR033753|reactome:R-DME-389661|reactome:R-DME-6783984 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:q959r4NQDKEw+ObhdPaOcH77UYU7227 rogid:9k5avM/K8XvE/4WTeS+6Rc312487227 intact-crc:8E1BCA1CDA208CEA|rigid:19RZY0LdwSHnE6+WTRyHGY17nyk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9Y0Y5 uniprotkb:Q8SY53 intact:EBI-85593|ensemblmetazoa:FBpp0078891 intact:EBI-2109067|uniprotkb:Q9VLP8|ensemblmetazoa:FBpp0079233 psi-mi:q9y0y5_drome(display_long)|uniprotkb:"BcDNA:LD29885"(gene name synonym)|uniprotkb:Dmel\CG9543(gene name synonym)|uniprotkb:epsilonCOP(gene name)|psi-mi:epsilonCOP(display_short)|uniprotkb:"bcDNA:LD29885"(gene name synonym)|uniprotkb:epsilon-Cop(gene name synonym)|uniprotkb:Dmel_CG9543(orf name)|uniprotkb:BcDNA.LD29885(gene name synonym)|uniprotkb:epsilon-COP(gene name synonym)|uniprotkb:CG9543(orf name) psi-mi:q8sy53_drome(display_long)|uniprotkb:CG7830(orf name)|uniprotkb:Ostgamma(gene name)|psi-mi:Ostgamma(display_short)|uniprotkb:Dmel\CG7830(gene name synonym)|uniprotkb:MagT1(gene name synonym)|uniprotkb:OST(gene name synonym)|uniprotkb:dMagT1(gene name synonym)|uniprotkb:Dmel_CG7830(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109064|imex:IM-9552-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609037.1|flybase:FBgn0027496|ensemblmetazoa:FBgn0027496(gene)|ensemblmetazoa:FBtr0079261(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-6807878|reactome:R-DME-6811434|go:"GO:0006891"(intra-Golgi vesicle-mediated transport) refseq:NP_609204.2|flybase:FBgn0032015|ensemblmetazoa:FBgn0032015(gene)|ensemblmetazoa:FBtr0079613(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016740"(transferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:1903830"(magnesium ion transmembrane transport)|interpro:IPR021149|interpro:IPR036249|reactome:R-DME-5223345|reactome:R-DME-6798695 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fYA58zdQsiZJFO13n1ArcwQuwqk7227 rogid:AcOe6DIkzUtMR2+BxhtQT/6ac447227 intact-crc:5458F301FFE056EC|rigid:Gkus5QmP19iIu2JsCTXKTBPJSz4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VU45 uniprotkb:Q23983 intact:EBI-2109083|ensemblmetazoa:FBpp0075620|ensemblmetazoa:FBpp0304386 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:q9vu45_drome(display_long)|uniprotkb:CG11278(orf name)|uniprotkb:Syx13(gene name)|psi-mi:Syx13(display_short)|uniprotkb:Dm Syx13(gene name synonym)|uniprotkb:DmSyx13(gene name synonym)|uniprotkb:Dmel\CG11278(gene name synonym)|uniprotkb:SYN13(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Syx20(gene name synonym)|uniprotkb:ff16(gene name synonym)|uniprotkb:"ff16 (69D1-70A2)"(gene name synonym)|uniprotkb:"l(3)01470"(gene name synonym)|uniprotkb:syx13(gene name synonym)|uniprotkb:Dmel_CG11278(orf name) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109080|imex:IM-9552-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524054.1|flybase:FBgn0036341|refseq:NP_001261794.1|ensemblmetazoa:FBgn0036341(gene)|ensemblmetazoa:FBtr0075886(transcript)|ensemblmetazoa:FBtr0332076(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:nPlziWcDUytXTioUug5kq14SKEs7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:7FCE6D88CEB5F1D9|rigid:kyHQmcyUTlm7LVHm5ziRSV78xyM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VF28 uniprotkb:Q9VIM5 intact:EBI-2109075|uniprotkb:Q29QX5|uniprotkb:Q8IND1|ensemblmetazoa:FBpp0289797|ensemblmetazoa:FBpp0306661 intact:EBI-143351|uniprotkb:Q95T07|ensemblmetazoa:FBpp0080890|ensemblmetazoa:FBpp0312086 psi-mi:q9vf28_drome(display_long)|uniprotkb:CG4560(orf name)|uniprotkb:Arpc3A(gene name)|psi-mi:Arpc3A(display_short)|uniprotkb:Arpc3A-RC(gene name synonym)|uniprotkb:ARC-P21(gene name synonym)|uniprotkb:ARPC(gene name synonym)|uniprotkb:Arpc3a(gene name synonym)|uniprotkb:Dmel\CG4560(gene name synonym)|uniprotkb:Dmel_CG4560(orf name) psi-mi:arpc2_drome(display_long)|uniprotkb:Arpc2(gene name)|psi-mi:Arpc2(display_short)|uniprotkb:Arc-p34(gene name synonym)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)|uniprotkb:CG10954(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109072|imex:IM-9552-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650498.3|refseq:NP_732075.3|flybase:FBgn0038369|ensemblmetazoa:FBgn0038369(gene)|ensemblmetazoa:FBtr0300570(transcript)|ensemblmetazoa:FBtr0334594(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-8856828 refseq:NP_610033.1|flybase:FBgn0032859|refseq:NP_001286102.1|dip:DIP-19044N|ensemblmetazoa:FBgn0032859(gene)|ensemblmetazoa:FBtr0081358(transcript)|ensemblmetazoa:FBtr0346418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-8856828 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2015/04/29 rogid:t6X8UqyL90nTjN9Ofj/7j1M9Xoc7227 rogid:Gsjx/EneyUFSvqD62cD8WqVJxMI7227 intact-crc:42C304F94A1ADCF5|rigid:XKuPvG3TOK2mUnA2ApZIJBDMQzM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18335 uniprotkb:Q9VK46 intact:EBI-148897|ensemblmetazoa:FBpp0083413|ensemblmetazoa:FBpp0083414 intact:EBI-182760|intact:EBI-1630152|ensemblmetazoa:FBpp0080011 psi-mi:o18335_drome(display_long)|uniprotkb:Rab11(gene name)|psi-mi:Rab11(display_short)|uniprotkb:Drab11(gene name synonym)|uniprotkb:CG5771(orf name)|uniprotkb:AAF55850(gene name synonym)|uniprotkb:DRAB11(gene name synonym)|uniprotkb:DRab11(gene name synonym)|uniprotkb:Dm Rab11(gene name synonym)|uniprotkb:DmRab11(gene name synonym)|uniprotkb:Dmel\CG5771(gene name synonym)|uniprotkb:O18335(gene name synonym)|uniprotkb:RAB11(gene name synonym)|uniprotkb:Rab 11(gene name synonym)|uniprotkb:Rab-11(gene name synonym)|uniprotkb:Rab-r11(gene name synonym)|uniprotkb:dRab11(gene name synonym)|uniprotkb:"l(3)93Bi"(gene name synonym)|uniprotkb:"l(3)j2D1"(gene name synonym)|uniprotkb:rab-11(gene name synonym)|uniprotkb:rab11(gene name synonym)|uniprotkb:rlr7(gene name synonym)|uniprotkb:Dmel_CG5771(orf name) psi-mi:q9vk46_drome(display_long)|uniprotkb:Yip1d1(gene name)|psi-mi:Yip1d1(display_short)|uniprotkb:Dmel\CG12404(gene name synonym)|uniprotkb:Yip1(gene name synonym)|uniprotkb:CG12404(orf name)|uniprotkb:Dmel_CG12404(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109089|imex:IM-9552-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477170.1|refseq:NP_599137.1|flybase:FBgn0015790|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030707"(ovarian follicle cell development)|ensemblmetazoa:FBgn0015790(gene)|ensemblmetazoa:FBtr0084010(transcript)|ensemblmetazoa:FBtr0084011(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003924"(GTPase activity)|dip:DIP-47764N|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045169"(fusome)|go:"GO:0045202"(synapse)|go:"GO:0045478"(fusome organization)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048599"(oocyte development)|go:"GO:0048749"(compound eye development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051642"(centrosome localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|go:"GO:0072657"(protein localization to membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:O18335|reactome:R-DME-432040|reactome:R-DME-5620916|reactome:R-DME-8873719 refseq:NP_609596.1|flybase:FBgn0032465|dip:DIP-18836N|ensemblmetazoa:FBgn0032465(gene)|ensemblmetazoa:FBtr0080430(transcript)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1905808"(positive regulation of synapse pruning)|interpro:IPR006977(Yip1 domain) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:rlrB7RSZlXyRgSO5ZjjN0nyRhe07227 rogid:JiFe0mxiBay45DuS8UjWtWVUwGw7227 intact-crc:9CFF3514875B7B0B|rigid:mxAwtZHNeDtcYOtgq6KSHXydsAg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VEU2 uniprotkb:E4NKJ7 intact:EBI-181131|ensemblmetazoa:FBpp0082758 intact:EBI-2109097|ensemblmetazoa:FBpp0071844 psi-mi:q9veu2_drome(display_long)|uniprotkb:Der-2(gene name)|psi-mi:Der-2(display_short)|uniprotkb:DER1(gene name synonym)|uniprotkb:Dmel\CG14899(gene name synonym)|uniprotkb:Cg14899(gene name synonym)|uniprotkb:dDer-2(gene name synonym)|uniprotkb:CG14899(orf name)|uniprotkb:Dmel_CG14899(orf name) psi-mi:e4nkj7_drome(display_long)|uniprotkb:CG2852-RA(gene name)|psi-mi:CG2852-RA(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109094|imex:IM-9552-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650553.1|flybase:FBgn0038438|ensemblmetazoa:FBgn0038438(gene)|ensemblmetazoa:FBtr0083307(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-DME-382556|reactome:R-DME-5358346 interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|ensemblmetazoa:FBgn0034753(gene)|ensemblmetazoa:FBtr0071933(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:j3WmB1mUT8e7QoPgMplnvGGmIoA7227 rogid:3aIBAqr3Fyg0C5AlSkwGpkjAE4c7227 intact-crc:FD5ADD2CBD8F3F12|rigid:PwIutszA3Xgu5Z5tSFefZ+38Bfs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97067 uniprotkb:Q9VNI3 intact:EBI-197419|uniprotkb:Q8MR09|uniprotkb:Q9VI42|intact:EBI-197428|ensemblmetazoa:FBpp0290838|ensemblmetazoa:FBpp0311968 intact:EBI-165768|ensemblmetazoa:FBpp0078279|uniprotkb:Q8T050 psi-mi:pth2_drome(display_long)|uniprotkb:CG1307(orf name) psi-mi:hpf1_drome(display_long)|uniprotkb:CG1218(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109103|imex:IM-9552-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287202.1|refseq:NP_649675.2|flybase:FBgn0026566|dip:DIP-17218N|ensemblmetazoa:FBgn0026566(gene)|ensemblmetazoa:FBtr0301623(transcript)|ensemblmetazoa:FBtr0346140(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476 ensemblmetazoa:FBgn0037377(gene)|ensemblmetazoa:FBtr0078630(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0042393"(histone binding)|go:"GO:0072572"(poly-ADP-D-ribose binding)|interpro:IPR019361|interpro:IPR019406|refseq:NP_649589.1|flybase:FBgn0037377 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:FIVtb+hVFAggFkSwKx3Ei8PfpYI7227 rogid:sBbYKqbix2btxxEXTAk9F7LzjUU7227 intact-crc:3F7B319D59929D89|rigid:GWHe+t3X3XGlNeDmQ9+ofiNyTsc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W3K3 uniprotkb:O97067 intact:EBI-105666|ensemblmetazoa:FBpp0071142 intact:EBI-197419|uniprotkb:Q8MR09|uniprotkb:Q9VI42|intact:EBI-197428|ensemblmetazoa:FBpp0290838|ensemblmetazoa:FBpp0311968 psi-mi:q9w3k3_drome(display_long)|uniprotkb:CG2260(orf name)|uniprotkb:Dmel\CG2260(gene name)|psi-mi:Dmel\CG2260(display_short)|uniprotkb:Dmel_CG2260(orf name) psi-mi:pth2_drome(display_long)|uniprotkb:CG1307(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109108|imex:IM-9552-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572441.1|flybase:FBgn0030000|ensemblmetazoa:FBgn0030000(gene)|ensemblmetazoa:FBtr0071194(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012952(BING4, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR040315|reactome:R-DME-6791226|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") refseq:NP_001287202.1|refseq:NP_649675.2|flybase:FBgn0026566|dip:DIP-17218N|ensemblmetazoa:FBgn0026566(gene)|ensemblmetazoa:FBtr0301623(transcript)|ensemblmetazoa:FBtr0346140(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:l8VxD5hUuMwwxbz+4NczYc0xl3M7227 rogid:FIVtb+hVFAggFkSwKx3Ei8PfpYI7227 intact-crc:BCB93BCA4BF2BDC0|rigid:7Ak7vKkp6P0r7Qj8LlQQFiuylo4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P91938 uniprotkb:Q0E924 intact:EBI-208742|uniprotkb:Q961E3|uniprotkb:Q9W3H2|uniprotkb:Q9W3H3|uniprotkb:Q1RKZ0|uniprotkb:Q53YG2|ensemblmetazoa:FBpp0071116 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 psi-mi:trxr1_drome(display_long)|uniprotkb:Trxr-1(gene name)|psi-mi:Trxr-1(display_short)|uniprotkb:GR(gene name synonym)|uniprotkb:CG2151(orf name) psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109113|imex:IM-9552-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511082.2|refseq:NP_727251.1|refseq:NP_727252.1|flybase:FBgn0020653|dip:DIP-19145N|ensemblmetazoa:FBgn0020653(gene)|ensemblmetazoa:FBtr0071168(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016209"(antioxidant activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2NVK|rcsb pdb:3DGH|rcsb pdb:3DH9|reactome:R-DME-3299685|reactome:R-DME-499943|reactome:R-DME-5263617|reactome:R-DME-5628897 refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9UYtoqz7kwWtFnWOX8rmwyYlY9M7227 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 intact-crc:507F33759E4188A8|rigid:Uv0b7Dk6mOw4E03hcCAjDg+lwFA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P91938 uniprotkb:Q9V784 intact:EBI-208742|uniprotkb:Q961E3|uniprotkb:Q9W3H2|uniprotkb:Q9W3H3|uniprotkb:Q1RKZ0|uniprotkb:Q53YG2|ensemblmetazoa:FBpp0071116 intact:EBI-2109126|uniprotkb:Q8STA1|ensemblmetazoa:FBpp0086555 psi-mi:trxr1_drome(display_long)|uniprotkb:Trxr-1(gene name)|psi-mi:Trxr-1(display_short)|uniprotkb:GR(gene name synonym)|uniprotkb:CG2151(orf name) psi-mi:sam50_drome(display_long)|uniprotkb:CG7639(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109123|imex:IM-9552-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511082.2|refseq:NP_727251.1|refseq:NP_727252.1|flybase:FBgn0020653|dip:DIP-19145N|ensemblmetazoa:FBgn0020653(gene)|ensemblmetazoa:FBtr0071168(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016209"(antioxidant activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2NVK|rcsb pdb:3DGH|rcsb pdb:3DH9|reactome:R-DME-3299685|reactome:R-DME-499943|reactome:R-DME-5263617|reactome:R-DME-5628897 refseq:NP_995838.1|flybase:FBgn0033989|ensemblmetazoa:FBgn0033989(gene)|ensemblmetazoa:FBtr0087424(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|reactome:R-DME-9013404 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9UYtoqz7kwWtFnWOX8rmwyYlY9M7227 rogid:6ieglq37hwK5bCQo9V18O9SUZxA7227 intact-crc:6E482275AB738D76|rigid:QcOv026FRknj3VCuchS4mmhCH1g false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P91938 uniprotkb:Q9V3H2 intact:EBI-208742|uniprotkb:Q961E3|uniprotkb:Q9W3H2|uniprotkb:Q9W3H3|uniprotkb:Q1RKZ0|uniprotkb:Q53YG2|ensemblmetazoa:FBpp0071116 intact:EBI-178674|uniprotkb:Q9NIU3|ensemblmetazoa:FBpp0078664 psi-mi:trxr1_drome(display_long)|uniprotkb:Trxr-1(gene name)|psi-mi:Trxr-1(display_short)|uniprotkb:GR(gene name synonym)|uniprotkb:CG2151(orf name) psi-mi:psde_drome(display_long)|uniprotkb:Rpn11(gene name)|psi-mi:Rpn11(display_short)|uniprotkb:CG18174(orf name)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym)|uniprotkb:26S proteasome regulatory complex subunit p37B(gene name synonym)|uniprotkb:Yippee-interacting protein 5(gene name synonym)|uniprotkb:yip5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109118|imex:IM-9552-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511082.2|refseq:NP_727251.1|refseq:NP_727252.1|flybase:FBgn0020653|dip:DIP-19145N|ensemblmetazoa:FBgn0020653(gene)|ensemblmetazoa:FBtr0071168(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016209"(antioxidant activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2NVK|rcsb pdb:3DGH|rcsb pdb:3DH9|reactome:R-DME-3299685|reactome:R-DME-499943|reactome:R-DME-5263617|reactome:R-DME-5628897 refseq:NP_608905.1|flybase:FBgn0028694|ensemblmetazoa:FBgn0028694(gene)|ensemblmetazoa:FBtr0079027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5689901|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9UYtoqz7kwWtFnWOX8rmwyYlY9M7227 rogid:7tJj3IGZzTi2DJujVlgT30KGpow7227 intact-crc:8EF5A98EEBF94978|rigid:nmpFOtIkQG2SLXB/KMudOz++El4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P08761 uniprotkb:O97121 intact:EBI-200482|uniprotkb:Q86NL3|uniprotkb:Q8IQM6|uniprotkb:Q8IT52|uniprotkb:Q9VUP3|uniprotkb:Q9VUP4|uniprotkb:Q9VUP5|ensemblmetazoa:FBpp0075308 intact:EBI-2108466 psi-mi:msra_drome(display_long)|uniprotkb:MsrA(gene name)|psi-mi:MsrA(display_short)|uniprotkb:Ecdysone-induced protein 28/29 kDa(gene name synonym)|uniprotkb:Eip28/29(gene name synonym)|uniprotkb:Eip71CD(gene name synonym)|uniprotkb:Methionine-S-sulfoxide reductase(gene name synonym)|uniprotkb:"Peptide-methionine (S)-S-oxide reductase"(gene name synonym)|uniprotkb:CG7266(orf name) psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109139|imex:IM-9552-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524085.2|refseq:NP_730047.1|flybase:FBgn0000565|ensemblmetazoa:FBgn0000565(gene)|ensemblmetazoa:FBtr0075553(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008113"("peptide-methionine (S)-S-oxide reductase activity")|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036456"("L-methionine-(S)-S-oxide reductase activity")|interpro:IPR002569(Methionine sulphoxide reductase A)|interpro:IPR036509 flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:p5rbqoIpgsabsC89nberhKj5j887227 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 intact-crc:C8D6953900CAB55A|rigid:XwA7xtzWboml0wdrdqorSYfhEvM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VUC3 uniprotkb:Q9VDL1 intact:EBI-1627788|ensemblmetazoa:FBpp0075516|ensemblmetazoa:FBpp0291625 intact:EBI-2109134|ensemblmetazoa:FBpp0083317 psi-mi:q9vuc3_drome(display_long)|uniprotkb:Dmel\CG6833(gene name)|psi-mi:Dmel\CG6833(display_short)|uniprotkb:REXO4(gene name synonym)|uniprotkb:CG6833(orf name)|uniprotkb:Dmel_CG6833(orf name) psi-mi:lovg_drome(display_long)|uniprotkb:CG5412(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109131|imex:IM-9552-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189105.1|refseq:NP_648689.1|flybase:FBgn0036405|ensemblmetazoa:FBgn0036405(gene)|ensemblmetazoa:FBtr0075774(transcript)|ensemblmetazoa:FBtr0302433(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|interpro:IPR037431 refseq:NP_650895.1|flybase:FBgn0038806|ensemblmetazoa:FBgn0038806(gene)|ensemblmetazoa:FBtr0083909(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0032526"(response to retinoic acid)|interpro:IPR005645(Protein of unknown function DUF341)|interpro:IPR029058 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ronrdK7nsTsabdivP66uD13RfSg7227 rogid:DtqwQKX9qDdyoQzVcPZ3nmkJhkU7227 intact-crc:E47B209B5C8AA669|rigid:i997SSrZd9AvR+oxqPA5WOK2vUM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P08761 uniprotkb:P40320 intact:EBI-200482|uniprotkb:Q86NL3|uniprotkb:Q8IQM6|uniprotkb:Q8IT52|uniprotkb:Q9VUP3|uniprotkb:Q9VUP4|uniprotkb:Q9VUP5|ensemblmetazoa:FBpp0075308 intact:EBI-203634|uniprotkb:Q0E8V3|uniprotkb:Q9VPJ2|uniprotkb:Q9VPJ3|uniprotkb:Q9VPJ4|uniprotkb:Q9VPJ5|ensemblmetazoa:FBpp0088445|ensemblmetazoa:FBpp0088446|ensemblmetazoa:FBpp0088448|ensemblmetazoa:FBpp0088449|ensemblmetazoa:FBpp0088450|ensemblmetazoa:FBpp0088926 psi-mi:msra_drome(display_long)|uniprotkb:MsrA(gene name)|psi-mi:MsrA(display_short)|uniprotkb:Ecdysone-induced protein 28/29 kDa(gene name synonym)|uniprotkb:Eip28/29(gene name synonym)|uniprotkb:Eip71CD(gene name synonym)|uniprotkb:Methionine-S-sulfoxide reductase(gene name synonym)|uniprotkb:"Peptide-methionine (S)-S-oxide reductase"(gene name synonym)|uniprotkb:CG7266(orf name) psi-mi:metk_drome(display_long)|uniprotkb:Sam-S(gene name)|psi-mi:Sam-S(display_short)|uniprotkb:SamS(gene name synonym)|uniprotkb:CG2674(orf name)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:"M(2)21AB"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109144|imex:IM-9552-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524085.2|refseq:NP_730047.1|flybase:FBgn0000565|ensemblmetazoa:FBgn0000565(gene)|ensemblmetazoa:FBtr0075553(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008113"("peptide-methionine (S)-S-oxide reductase activity")|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036456"("L-methionine-(S)-S-oxide reductase activity")|interpro:IPR002569(Methionine sulphoxide reductase A)|interpro:IPR036509 refseq:NP_524923.1|refseq:NP_722593.1|refseq:NP_722594.1|refseq:NP_722595.1|refseq:NP_722596.1|refseq:NP_722597.1|refseq:NP_722598.1|refseq:NP_722599.1|refseq:NP_722600.1|refseq:NP_995602.1|flybase:FBgn0005278|dip:DIP-18340N|ensemblmetazoa:FBgn0005278(gene)|ensemblmetazoa:FBtr0089429(transcript)|ensemblmetazoa:FBtr0089430(transcript)|ensemblmetazoa:FBtr0089432(transcript)|ensemblmetazoa:FBtr0089433(transcript)|ensemblmetazoa:FBtr0089434(transcript)|ensemblmetazoa:FBtr0089437(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:p5rbqoIpgsabsC89nberhKj5j887227 rogid:COUl0nv83GMZge7edbQNfqgn2dQ7227 intact-crc:A157E772073C7C91|rigid:8hAwHh3XV0nOr/dkAuiahv+Dqw0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P54399 uniprotkb:O97121 intact:EBI-123796|uniprotkb:Q9VUL7|uniprotkb:Q53YH5|uniprotkb:Q86PE2|uniprotkb:Q8IQL8|ensemblmetazoa:FBpp0075401|ensemblmetazoa:FBpp0312224 intact:EBI-2108466 psi-mi:pdi_drome(display_long)|uniprotkb:Pdi(gene name)|psi-mi:Pdi(display_short)|uniprotkb:CG6988(orf name) psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109149|imex:IM-9552-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524079.1|refseq:NP_001287070.1|ensemblmetazoa:FBgn0286818(gene)|ensemblmetazoa:FBtr0075648(transcript)|ensemblmetazoa:FBtr0346644(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045169"(fusome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-DME-381426|reactome:R-DME-5358346|reactome:R-DME-8957275|dip:DIP-21766N|flybase:FBgn0286818 flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:5WvkcBmjcDkzw5HGvxX9J30oLL47227 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 intact-crc:338EBD855ACDA8E3|rigid:ZOKIz6950vILHb/rbD3dk5+fOdE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40320 uniprotkb:O97121 intact:EBI-203634|uniprotkb:Q0E8V3|uniprotkb:Q9VPJ2|uniprotkb:Q9VPJ3|uniprotkb:Q9VPJ4|uniprotkb:Q9VPJ5|ensemblmetazoa:FBpp0088445|ensemblmetazoa:FBpp0088446|ensemblmetazoa:FBpp0088448|ensemblmetazoa:FBpp0088449|ensemblmetazoa:FBpp0088450|ensemblmetazoa:FBpp0088926 intact:EBI-2108466 psi-mi:metk_drome(display_long)|uniprotkb:Sam-S(gene name)|psi-mi:Sam-S(display_short)|uniprotkb:SamS(gene name synonym)|uniprotkb:CG2674(orf name)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:"M(2)21AB"(gene name synonym) psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109154|imex:IM-9552-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524923.1|refseq:NP_722593.1|refseq:NP_722594.1|refseq:NP_722595.1|refseq:NP_722596.1|refseq:NP_722597.1|refseq:NP_722598.1|refseq:NP_722599.1|refseq:NP_722600.1|refseq:NP_995602.1|flybase:FBgn0005278|dip:DIP-18340N|ensemblmetazoa:FBgn0005278(gene)|ensemblmetazoa:FBtr0089429(transcript)|ensemblmetazoa:FBtr0089430(transcript)|ensemblmetazoa:FBtr0089432(transcript)|ensemblmetazoa:FBtr0089433(transcript)|ensemblmetazoa:FBtr0089434(transcript)|ensemblmetazoa:FBtr0089437(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636 flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:COUl0nv83GMZge7edbQNfqgn2dQ7227 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 intact-crc:6CF470101C308BCC|rigid:J0Wjt42nLuPQtomiNZfrA0KIngE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97121 uniprotkb:Q86NZ5 intact:EBI-2108466 intact:EBI-2108877|ensemblmetazoa:FBpp0075630 psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:q86nz5_drome(display_long)|uniprotkb:Adk2(gene name)|psi-mi:Adk2(display_short)|uniprotkb:AdenoK(gene name synonym)|uniprotkb:CG11255(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109159|imex:IM-9552-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) flybase:FBgn0036337|ensemblmetazoa:FBgn0036337(gene)|ensemblmetazoa:FBtr0075896(transcript)|go:"GO:0004001"(adenosine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0044209"(AMP salvage)|interpro:IPR001805(Adenosine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 rogid:BckVO3R4s6Dak7eTLqxtkb2XpFI7227 intact-crc:DCDAA38450504A3C|rigid:+FJTc3/pcu2fOuuLwDkSyQ1TErU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97121 uniprotkb:Q9VYD5 intact:EBI-2108466 intact:EBI-2109167|ensemblmetazoa:FBpp0073608 psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:q9vyd5_drome(display_long)|uniprotkb:Dmel\CG1673(gene name)|psi-mi:Dmel\CG1673(display_short)|uniprotkb:cg1673(gene name synonym)|uniprotkb:CG1673(orf name)|uniprotkb:Dmel_CG1673(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109164|imex:IM-9552-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) refseq:NP_572884.1|flybase:FBgn0030482|ensemblmetazoa:FBgn0030482(gene)|ensemblmetazoa:FBtr0073777(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006551"(leucine metabolic process)|go:"GO:0006573"(valine metabolic process)|go:"GO:0009081"(branched-chain amino acid metabolic process)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|reactome:R-DME-70895 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 rogid:Urcq6NcngmW2FTxvkoqXq8+kZ8c7227 intact-crc:CF2E098AA0624333|rigid:qWc8chIXWK9xbLinsrMIQA+0ZZw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VD65 uniprotkb:Q2XYK6 intact:EBI-162129|ensemblmetazoa:FBpp0083550 intact:EBI-2109175|ensemblmetazoa:FBpp0076438 psi-mi:q9vd65_drome(display_long)|uniprotkb:"BcDNA:LP07781"(gene name)|psi-mi:"BcDNA:LP07781"(display_short)|uniprotkb:Dmel\CG17819(gene name synonym)|uniprotkb:CG17819(orf name)|uniprotkb:Dmel_CG17819(orf name) psi-mi:q2xyk6_drome(display_long)|uniprotkb:CG7197(orf name)|uniprotkb:Arl5(gene name)|psi-mi:Arl5(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109172|imex:IM-9552-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0038915(gene)|ensemblmetazoa:FBtr0084152(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|refseq:NP_650994.1|flybase:FBgn0038915 flybase:FBgn0035866|ensemblmetazoa:FBgn0035866(gene)|ensemblmetazoa:FBtr0076715(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:1903292"(protein localization to Golgi membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fohbMQo+ejQuIbGLsVwIHYl1ZEo7227 rogid:bLb2OLL/ojy5YL3omSio0g0HUHA7227 intact-crc:A1B4E718005E4A5A|rigid:zEKEKqbfaCBgml3TxbUXcLRIfoE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SYC8 uniprotkb:Q29QQ9 intact:EBI-2109185 intact:EBI-123608|intact:EBI-2109181|ensemblmetazoa:FBpp0086348 psi-mi:q8syc8_drome(display_long)|uniprotkb:CG15481(orf name)|uniprotkb:Ski6(gene name)|psi-mi:Ski6(display_short) psi-mi:q29qq9_drome(display_long)|uniprotkb:Rrp42(gene name)|psi-mi:Rrp42(display_short)|uniprotkb:Dmel\CG8395(gene name synonym)|uniprotkb:"anon-EST:Posey140"(gene name synonym)|uniprotkb:"anon-EST:Posey187"(gene name synonym)|uniprotkb:dRrp42(gene name synonym)|uniprotkb:CG8395(orf name)|uniprotkb:Dmel_CG8395(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109190|imex:IM-9552-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0032487|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345 refseq:NP_725517.2|flybase:FBgn0034065|ensemblmetazoa:FBgn0034065(gene)|ensemblmetazoa:FBtr0087206(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|reactome:R-DME-429958|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-6791226 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:11s6l6e8OGtwBuVKtc3fX82Pztg7227 rogid:kXWZAL7cUNBc5VEfLubZyh6DJqQ7227 intact-crc:A450935634B41DD1|rigid:hrIpU3h+bMhYZszZkGFMJbcFGVE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IFW3 uniprotkb:Q86B98 intact:EBI-2109201 intact:EBI-2109198|ensemblmetazoa:FBpp0081955 psi-mi:q8ifw3_drome(display_long)|uniprotkb:CG8383(orf name)|uniprotkb:Pnn(gene name)|psi-mi:Pnn(display_short) psi-mi:q86b98_drome(display_long)|uniprotkb:Dmel_CG31211(orf name)|uniprotkb:CG18546(gene name)|psi-mi:CG18546(display_short)|uniprotkb:CG14732(gene name synonym)|uniprotkb:Dmel\CG31211(gene name synonym)|uniprotkb:anon-WO03070958.3(gene name synonym)|uniprotkb:cDNA(gene name synonym)|uniprotkb:CG31211(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109195|imex:IM-9552-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0037737|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR039853 refseq:NP_788642.1|flybase:FBgn0051211|ensemblmetazoa:FBgn0051211(gene)|ensemblmetazoa:FBtr0082481(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR031937 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PRyU9fdEfKBFeQgOwSNOYGXdnwA7227 rogid:dcNNqhNZCH5cuWSBmfPH+qM7qFU7227 intact-crc:4EDF3798DE1E71B8|rigid:pK4yDPr9zuuY5ROP3ehb2Ot6q1E false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SYM9 uniprotkb:Q5BI58 intact:EBI-170383|uniprotkb:Q9VVN3|ensemblmetazoa:FBpp0074902 intact:EBI-870744 psi-mi:q8sym9_drome(display_long)|uniprotkb:Polr3D(gene name)|psi-mi:Polr3D(display_short)|uniprotkb:CG5147-RA(gene name synonym)|uniprotkb:Dmel\CG5147(gene name synonym)|uniprotkb:RpIIIC53(gene name synonym)|uniprotkb:Rpc53(gene name synonym)|uniprotkb:dC53(gene name synonym)|uniprotkb:CG5147(orf name)|uniprotkb:Dmel_CG5147(orf name) psi-mi:q5bi58_drome(display_long)|uniprotkb:Polr3E(gene name)|psi-mi:Polr3E(display_short)|uniprotkb:Sin(gene name synonym)|uniprotkb:CG10582(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109208|imex:IM-9552-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649028.3|flybase:FBgn0036775|ensemblmetazoa:FBgn0036775(gene)|ensemblmetazoa:FBtr0075136(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006383"(transcription by RNA polymerase III)|interpro:IPR007811(RNA polymerase III Rpc4)|reactome:R-DME-76061|reactome:R-DME-76066 flybase:FBgn0028402|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR006886(Sin-like protein conserved region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Q/U3+QYQ9MSzm392qy5VbJRM9Nc7227 rogid:yQ2Q0DiBwh9DwQWIG2nZqVkADRk7227 intact-crc:751747304AD7CF8C|rigid:EGCMAXe78+j41gGq+lmyJPbZY5g false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VD65 uniprotkb:P61209 intact:EBI-162129|ensemblmetazoa:FBpp0083550 intact:EBI-123053|uniprotkb:P35676|uniprotkb:Q9VNQ2|uniprotkb:A4V2B1|uniprotkb:A8JNX4|ensemblmetazoa:FBpp0078222|ensemblmetazoa:FBpp0078224|ensemblmetazoa:FBpp0078225|ensemblmetazoa:FBpp0078226|ensemblmetazoa:FBpp0111771|ensemblmetazoa:FBpp0289184|ensemblmetazoa:FBpp0289185|ensemblmetazoa:FBpp0304364 psi-mi:q9vd65_drome(display_long)|uniprotkb:"BcDNA:LP07781"(gene name)|psi-mi:"BcDNA:LP07781"(display_short)|uniprotkb:Dmel\CG17819(gene name synonym)|uniprotkb:CG17819(orf name)|uniprotkb:Dmel_CG17819(orf name) psi-mi:arf1_drome(display_long)|uniprotkb:Arf79F(gene name)|psi-mi:Arf79F(display_short)|uniprotkb:ARF1(gene name synonym)|uniprotkb:CG8385(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109213|imex:IM-9552-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0038915(gene)|ensemblmetazoa:FBtr0084152(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|refseq:NP_650994.1|flybase:FBgn0038915 refseq:NP_001097667.1|refseq:NP_001097668.2|refseq:NP_476955.1|refseq:NP_730757.1|refseq:NP_730758.1|refseq:NP_730759.1|refseq:NP_730760.1|flybase:FBgn0010348|ensemblmetazoa:FBgn0010348(gene)|ensemblmetazoa:FBtr0078573(transcript)|ensemblmetazoa:FBtr0078574(transcript)|ensemblmetazoa:FBtr0078575(transcript)|ensemblmetazoa:FBtr0112858(transcript)|ensemblmetazoa:FBtr0299906(transcript)|ensemblmetazoa:FBtr0299907(transcript)|ensemblmetazoa:FBtr0332054(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002786"(regulation of antibacterial peptide production)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|ensemblmetazoa:FBtr0078571(transcript)|refseq:NP_001262225.1|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032011"(ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048749"(compound eye development)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-DME-1660499|reactome:R-DME-1660514|reactome:R-DME-199992|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fohbMQo+ejQuIbGLsVwIHYl1ZEo7227 rogid:jll+4R7SmNOLqJPE6qrJ6NJ+awg7227 intact-crc:E00727E0B211978F|rigid:gfOUVQbOn3t7By0hhqtj6TDyDX8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q23983 uniprotkb:Q9W0N6 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 intact:EBI-119356|ensemblmetazoa:FBpp0072503 psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:q9w0n6_drome(display_long)|uniprotkb:Vti1a(gene name)|psi-mi:Vti1a(display_short)|uniprotkb:Vti1(gene name synonym)|uniprotkb:Dmel\CG3279(gene name synonym)|uniprotkb:VTI1(gene name synonym)|uniprotkb:Vti1A(gene name synonym)|uniprotkb:vti1a(gene name synonym)|uniprotkb:CG3279(orf name)|uniprotkb:Dmel_CG3279(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109218|imex:IM-9552-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 refseq:NP_612053.1|flybase:FBgn0260862|ensemblmetazoa:FBgn0260862(gene)|ensemblmetazoa:FBtr0072607(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 rogid:zNV6ODbviT5S3Xp6A6VYaJA1FCg7227 intact-crc:7724DA2ED7C71A29|rigid:DoRJxn3wQAZb+BX/nTHdqv+QAB4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W139 uniprotkb:Q9V7N5 intact:EBI-2109228|ensemblmetazoa:FBpp0072223 intact:EBI-265137|uniprotkb:O18365|uniprotkb:Q0E956|uniprotkb:Q869C0|uniprotkb:Q95RY7|uniprotkb:Q9V7N6|ensemblmetazoa:FBpp0288470|ensemblmetazoa:FBpp0288471|uniprotkb:Q5U1B8|uniprotkb:Q9V7N7 psi-mi:q9w139_drome(display_long)|uniprotkb:anon-WO0140519.176(gene name)|psi-mi:anon-WO0140519.176(display_short)|uniprotkb:Dmel\CG3565(gene name synonym)|uniprotkb:Dmel_CG3565(orf name)|uniprotkb:CG3565(orf name) psi-mi:vatc_drome(display_long)|uniprotkb:Vha44(gene name)|psi-mi:Vha44(display_short)|uniprotkb:"l(2)06072"(gene name synonym)|uniprotkb:CG8048(orf name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109231|imex:IM-9552-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611942.1|flybase:FBgn0035034|ensemblmetazoa:FBgn0035034(gene)|ensemblmetazoa:FBtr0072316(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR028846 ensemblmetazoa:FBgn0262511(gene)|ensemblmetazoa:FBtr0290031(transcript)|ensemblmetazoa:FBtr0290032(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|refseq:NP_001137679.1|refseq:NP_477266.1|refseq:NP_599140.1|refseq:NP_725564.1|refseq:NP_725565.3|flybase:FBgn0287825 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xsvl/y193WyRai4IFE7xiK7EWvY7227 rogid:xBxBMubWEmxx0u6mj/Hl7gMuvOU7227 intact-crc:36C6076EE9B1AB71|rigid:RWElNOYMj8Tiw7X6HMkInsS/5rY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P21914 uniprotkb:Q9VHB1 intact:EBI-136047|uniprotkb:Q9V9A0|ensemblmetazoa:FBpp0085489 intact:EBI-89809|ensemblmetazoa:FBpp0081587|ensemblmetazoa:FBpp0081588|ensemblmetazoa:FBpp0306718 psi-mi:sdhb_drome(display_long)|uniprotkb:SdhB(gene name)|psi-mi:SdhB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:CG3283(orf name)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym) psi-mi:q9vhb1_drome(display_long)|uniprotkb:Dmel_CG9399(orf name)|uniprotkb:Dmel\CG9399(gene name)|psi-mi:Dmel\CG9399(display_short)|uniprotkb:CG9399(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109223|imex:IM-9552-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-DME-71403|refseq:NP_477101.1|flybase:FBgn0014028|ensemblmetazoa:FBgn0014028(gene)|ensemblmetazoa:FBtr0086156(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0009055"(electron transfer activity)|dip:DIP-20115N ensemblmetazoa:FBgn0037715(gene)|ensemblmetazoa:FBtr0082109(transcript)|ensemblmetazoa:FBtr0082110(transcript)|ensemblmetazoa:FBtr0334656(transcript)|go:"GO:0006850"(mitochondrial pyruvate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050833"(pyruvate transmembrane transporter activity)|interpro:IPR005336(Protein of unknown function UPF0041)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|refseq:NP_001163571.1|refseq:NP_649913.1|refseq:NP_731376.1|flybase:FBgn0037715 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xtvWH/0V/SoBZ6cfsHV7vnjugKw7227 rogid:j8+l+VYPYPA+Zr12o8yIde6LKB87227 intact-crc:4B451C7E00EC954B|rigid:XhQvF6x/AgOjqKvFHRKXdWLarro false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q4V5H8 uniprotkb:Q9V7N5 intact:EBI-2109239|uniprotkb:Q9VI38|ensemblmetazoa:FBpp0081199 intact:EBI-265137|uniprotkb:O18365|uniprotkb:Q0E956|uniprotkb:Q869C0|uniprotkb:Q95RY7|uniprotkb:Q9V7N6|ensemblmetazoa:FBpp0288470|ensemblmetazoa:FBpp0288471|uniprotkb:Q5U1B8|uniprotkb:Q9V7N7 psi-mi:q4v5h8_drome(display_long)|uniprotkb:CG15178(orf name)|uniprotkb:sowi(gene name)|psi-mi:sowi(display_short)|uniprotkb:Dmel\CG15178(gene name synonym)|uniprotkb:Dmel_CG15178(orf name) psi-mi:vatc_drome(display_long)|uniprotkb:Vha44(gene name)|psi-mi:Vha44(display_short)|uniprotkb:"l(2)06072"(gene name synonym)|uniprotkb:CG8048(orf name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109236|imex:IM-9552-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649671.2|flybase:FBgn0037460|ensemblmetazoa:FBgn0037460(gene)|ensemblmetazoa:FBtr0081701(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846 ensemblmetazoa:FBgn0262511(gene)|ensemblmetazoa:FBtr0290031(transcript)|ensemblmetazoa:FBtr0290032(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|refseq:NP_001137679.1|refseq:NP_477266.1|refseq:NP_599140.1|refseq:NP_725564.1|refseq:NP_725565.3|flybase:FBgn0287825 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:c6R+rUXSkhV3w5y+3Bwzj2wA3xA7227 rogid:xBxBMubWEmxx0u6mj/Hl7gMuvOU7227 intact-crc:264A974FA885E9D6|rigid:Ruz3PvN6gPP6GEIHnwhfCxZ5EmI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFQ4 uniprotkb:Q9V7N5 intact:EBI-115751|ensemblmetazoa:FBpp0082344 intact:EBI-265137|uniprotkb:O18365|uniprotkb:Q0E956|uniprotkb:Q869C0|uniprotkb:Q95RY7|uniprotkb:Q9V7N6|ensemblmetazoa:FBpp0288470|ensemblmetazoa:FBpp0288471|uniprotkb:Q5U1B8|uniprotkb:Q9V7N7 psi-mi:q9vfq4_drome(display_long)|uniprotkb:Dmel\CG14362(gene name)|psi-mi:Dmel\CG14362(display_short)|uniprotkb:CBP10(gene name synonym)|uniprotkb:CG14362(orf name)|uniprotkb:Dmel_CG14362(orf name) psi-mi:vatc_drome(display_long)|uniprotkb:Vha44(gene name)|psi-mi:Vha44(display_short)|uniprotkb:"l(2)06072"(gene name synonym)|uniprotkb:CG8048(orf name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109249|imex:IM-9552-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0038186(gene)|ensemblmetazoa:FBtr0082881(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_650320.1|flybase:FBgn0038186 ensemblmetazoa:FBgn0262511(gene)|ensemblmetazoa:FBtr0290031(transcript)|ensemblmetazoa:FBtr0290032(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|refseq:NP_001137679.1|refseq:NP_477266.1|refseq:NP_599140.1|refseq:NP_725564.1|refseq:NP_725565.3|flybase:FBgn0287825 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:R3gXqcIu+FwS2w3DYXKCuPuhrpM7227 rogid:xBxBMubWEmxx0u6mj/Hl7gMuvOU7227 intact-crc:C2B56F6152B7B759|rigid:sOIjb6H+yDW31i/emdK+SL45VGY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VI39 uniprotkb:Q9V7N5 intact:EBI-153376|ensemblmetazoa:FBpp0081198 intact:EBI-265137|uniprotkb:O18365|uniprotkb:Q0E956|uniprotkb:Q869C0|uniprotkb:Q95RY7|uniprotkb:Q9V7N6|ensemblmetazoa:FBpp0288470|ensemblmetazoa:FBpp0288471|uniprotkb:Q5U1B8|uniprotkb:Q9V7N7 psi-mi:q9vi39_drome(display_long)|uniprotkb:Dmel\CG15177(gene name)|psi-mi:Dmel\CG15177(display_short)|uniprotkb:CG15177(orf name)|uniprotkb:Dmel_CG15177(orf name) psi-mi:vatc_drome(display_long)|uniprotkb:Vha44(gene name)|psi-mi:Vha44(display_short)|uniprotkb:"l(2)06072"(gene name synonym)|uniprotkb:CG8048(orf name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109244|imex:IM-9552-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649672.1|flybase:FBgn0037461|ensemblmetazoa:FBgn0037461(gene)|ensemblmetazoa:FBtr0081700(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846 ensemblmetazoa:FBgn0262511(gene)|ensemblmetazoa:FBtr0290031(transcript)|ensemblmetazoa:FBtr0290032(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|refseq:NP_001137679.1|refseq:NP_477266.1|refseq:NP_599140.1|refseq:NP_725564.1|refseq:NP_725565.3|flybase:FBgn0287825 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:HfLsAEF7megYMsHieVYE8W5cpaI7227 rogid:xBxBMubWEmxx0u6mj/Hl7gMuvOU7227 intact-crc:B5ED0149667F959F|rigid:YNYnvAHWhYXjrOEktRi1J0xWYwE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K0E6 uniprotkb:Q9VUR3 intact:EBI-128833|intact:EBI-2109257|ensemblmetazoa:FBpp0086897|ensemblmetazoa:FBpp0305104|ensemblmetazoa:FBpp0308483 intact:EBI-96472|ensemblmetazoa:FBpp0075318 psi-mi:q7k0e6_drome(display_long)|uniprotkb:AspRS(gene name)|psi-mi:AspRS(display_short)|uniprotkb:Aats-asp(gene name synonym)|uniprotkb:Aats-Asp(gene name synonym)|uniprotkb:DRS(gene name synonym)|uniprotkb:Dmel\CG3821(gene name synonym)|uniprotkb:aats-asp(gene name synonym)|uniprotkb:"anon-EST:Liang-2.49"(gene name synonym)|uniprotkb:cDNA1(gene name synonym)|uniprotkb:clone 2.49(gene name synonym)|uniprotkb:"l(2)49Db"(gene name synonym)|uniprotkb:"l(2)k04508"(gene name synonym)|uniprotkb:"l(2)v27"(gene name synonym)|uniprotkb:"l(2)vr1"(gene name synonym)|uniprotkb:poney(gene name synonym)|uniprotkb:vr1(gene name synonym)|uniprotkb:CG3821(orf name)|uniprotkb:Dmel_CG3821(orf name)|uniprotkb:"aaRS(Asp)"(gene name synonym)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:aimp2_drome(display_long)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:Probable multisynthase complex auxiliary component p38(gene name synonym)|uniprotkb:aaRS-interacting multifunctional protein 2(gene name synonym)|uniprotkb:CG12304(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109254|imex:IM-9552-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476609.1|flybase:FBgn0002069|ensemblmetazoa:FBtr0332882(transcript)|ensemblmetazoa:FBtr0339391(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|ensemblmetazoa:FBgn0002069(gene)|ensemblmetazoa:FBtr0087784(transcript)|refseq:NP_001260930.1|refseq:NP_001260931.1 refseq:NP_648782.2|flybase:FBgn0036515|ensemblmetazoa:FBgn0036515(gene)|ensemblmetazoa:FBtr0075565(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|dip:DIP-20389N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:mCQLozemd5RQb56T9/qt5jApRms7227 rogid:t3QTchgVJ8nv+cK13mI4K51RtOo7227 intact-crc:EFD1DB40686566C8|rigid:chY8HRnTRirTG43EmmbLJ/LZzsA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q0E924 uniprotkb:Q9V3H2 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 intact:EBI-178674|uniprotkb:Q9NIU3|ensemblmetazoa:FBpp0078664 psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:psde_drome(display_long)|uniprotkb:Rpn11(gene name)|psi-mi:Rpn11(display_short)|uniprotkb:CG18174(orf name)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym)|uniprotkb:26S proteasome regulatory complex subunit p37B(gene name synonym)|uniprotkb:Yippee-interacting protein 5(gene name synonym)|uniprotkb:yip5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109264|imex:IM-9552-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 refseq:NP_608905.1|flybase:FBgn0028694|ensemblmetazoa:FBgn0028694(gene)|ensemblmetazoa:FBtr0079027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5689901|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 rogid:7tJj3IGZzTi2DJujVlgT30KGpow7227 intact-crc:CCDD902C7AF7E9EC|rigid:Mx7YuRO+bX/n/1WcCHITlR6A3Q0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q0E924 uniprotkb:Q8IHE3 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 intact:EBI-2109269 psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:q8ihe3_drome(display_long)|uniprotkb:CG11779(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109272|imex:IM-9552-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 flybase:FBgn0038683|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0051087"(chaperone binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR017303(Import inner membrane translocase, TIM44 subunit, mitochondria)|interpro:IPR032710|interpro:IPR039544 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 rogid:gpHo7+Gc8+ktDHkO7oux2/nnMm07227 intact-crc:BC433D899E64A439|rigid:3bIuenkskr2iq9rZ1G3d5Mv8Haw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A5XCL5 uniprotkb:Q0E924 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109277|imex:IM-9552-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 intact-crc:31A7BBA649FB7D4A|rigid:wpFGR40moMBGBS7SPLORYRHpoVk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V3D0 uniprotkb:Q0E924 intact:EBI-2109286|ensemblmetazoa:FBpp0080401 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 psi-mi:q9v3d0_drome(display_long)|uniprotkb:CG5818(orf name)|uniprotkb:mRpL4(gene name)|psi-mi:mRpL4(display_short)|uniprotkb:"BG:DS02740.17"(gene name synonym)|uniprotkb:Dmel\CG5818(gene name synonym)|uniprotkb:L4(gene name synonym)|uniprotkb:Rpl4(gene name synonym)|uniprotkb:"l(2)35Fe"(gene name synonym)|uniprotkb:"l(2)k14608"(gene name synonym)|uniprotkb:l35Fe(gene name synonym)|uniprotkb:mrpL4(gene name synonym)|uniprotkb:Dmel_CG5818(orf name) psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109291|imex:IM-9552-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524939.1|flybase:FBgn0001995|ensemblmetazoa:FBgn0001995(gene)|ensemblmetazoa:FBtr0080843(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|reactome:R-DME-5389840|reactome:R-DME-5419276 refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PZQEwLbpRvJHWWgpF+w75s3pU5o7227 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 intact-crc:088FD0908A6B6CF2|rigid:8ggIw0iAh/E1tPA2NcYdi0/Q0ZU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q0E924 uniprotkb:Q8MRV7 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 intact:EBI-2109296 psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:q8mrv7_drome(display_long)|uniprotkb:mRpL3(gene name)|psi-mi:mRpL3(display_short)|uniprotkb:CG8288(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109300|imex:IM-9552-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 flybase:FBgn0030686|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019927 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 rogid:1cLwoHe3+eYgQTDdI3SfOlIuoFs7227 intact-crc:B69EC4FC8201ABA1|rigid:1NsnQVx0q4rALt5HxE6AFpfwmaM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) intact:EBI-2108411 uniprotkb:Q27884 - intact:EBI-99228|uniprotkb:Q5BIJ4|uniprotkb:Q8MRZ7|uniprotkb:Q9W3Z8|ensemblmetazoa:FBpp0070883|ensemblmetazoa:FBpp0303847|ensemblmetazoa:FBpp0303848|ensemblmetazoa:FBpp0303849 psi-mi:q8img7_drome(display_short)|psi-mi:EBI-2108411(display_long)|uniprotkb:Dmel_CG11525(orf name)|uniprotkb:CycG(gene name)|psi-mi:CycG(display_short)|uniprotkb:CG11525(orf name) psi-mi:ppp6_drome(display_long)|uniprotkb:PpV(gene name)|psi-mi:PpV(display_short)|uniprotkb:PPPV6A(gene name synonym)|uniprotkb:CG12217(orf name)|uniprotkb:Phosphatase V(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109310|imex:IM-9552-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IMG7(uniprot-removed-ac) refseq:NP_511061.1|flybase:FBgn0003139|refseq:NP_001259272.1|refseq:NP_001259273.1|refseq:NP_001259274.1|ensemblmetazoa:FBgn0003139(gene)|ensemblmetazoa:FBtr0070921(transcript)|ensemblmetazoa:FBtr0331430(transcript)|ensemblmetazoa:FBtr0331431(transcript)|ensemblmetazoa:FBtr0331432(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|dip:DIP-20494N psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GwDM/XQ/mtqkftw2t9BwmojZmFA7227 rogid:EO7pNWevzqdO1j5I6OVUdRjjWCs7227 intact-crc:BE8377C93EE2F141|rigid:38S8ujK/G3LfyLEdlFsbKlo6B4w false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFV9 intact:EBI-2108411 intact:EBI-121507|ensemblmetazoa:FBpp0082219|ensemblmetazoa:FBpp0082220|ensemblmetazoa:FBpp0082221|ensemblmetazoa:FBpp0082222|ensemblmetazoa:FBpp0082223 - psi-mi:q9vfv9_drome(display_long)|uniprotkb:Droj2(gene name)|psi-mi:Droj2(display_short)|uniprotkb:CG8863(orf name)|uniprotkb:DnaJL2A(gene name synonym)|uniprotkb:anon-WO0118547.404(gene name synonym)|uniprotkb:Dmel_CG8863(orf name)|uniprotkb:DROJ2(gene name synonym)|uniprotkb:Dmel\CG8863(gene name synonym)|uniprotkb:Hsp40(gene name synonym) psi-mi:q8img7_drome(display_short)|psi-mi:EBI-2108411(display_long)|uniprotkb:Dmel_CG11525(orf name)|uniprotkb:CycG(gene name)|psi-mi:CycG(display_short)|uniprotkb:CG11525(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109305|imex:IM-9552-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650283.1|refseq:NP_731804.1|refseq:NP_731805.1|refseq:NP_731806.1|refseq:NP_731807.1|flybase:FBgn0038145|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|ensemblmetazoa:FBgn0038145(gene)|reactome:R-DME-3371497|ensemblmetazoa:FBtr0082751(transcript)|ensemblmetazoa:FBtr0082752(transcript)|ensemblmetazoa:FBtr0082753(transcript)|ensemblmetazoa:FBtr0082754(transcript)|ensemblmetazoa:FBtr0082755(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding) uniprotkb:Q8IMG7(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:2SIHKEbZ/eKMfB2gLDRtjBat+V47227 rogid:GwDM/XQ/mtqkftw2t9BwmojZmFA7227 intact-crc:E98F4E184D5A31B0|rigid:cR7lUnKIFsePjcVxS7aveXrd3eQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q7JVY0 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-102727|intact:EBI-2109323|ensemblmetazoa:FBpp0085526|ensemblmetazoa:FBpp0085527|ensemblmetazoa:FBpp0089194 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q7jvy0_drome(display_long)|uniprotkb:coro(gene name)|psi-mi:coro(display_short)|uniprotkb:Dmel\CG9446(gene name synonym)|uniprotkb:"l(2)k08011"(gene name synonym)|uniprotkb:CG9446(orf name)|uniprotkb:Dmel_CG9446(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109320|imex:IM-9552-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_610242.1|refseq:NP_724509.1|refseq:NP_995753.1|flybase:FBgn0265935|ensemblmetazoa:FBtr0086207(transcript)|ensemblmetazoa:FBtr0086208(transcript)|ensemblmetazoa:FBtr0086209(transcript)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0050832"(defense response to fungus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|ensemblmetazoa:FBgn0265935(gene) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:s2diIF/MH53Rwt9YUgMaSw2M29c7227 intact-crc:E55CE2723D34C4DE|rigid:v6j7XtNgTf4I7tPBsT6Ecmnj1Gg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VUZ0 uniprotkb:P23380 intact:EBI-113522|uniprotkb:Q9U9P9|ensemblmetazoa:FBpp0075209 intact:EBI-185634|uniprotkb:A4UZ55|uniprotkb:Q0E9N6|uniprotkb:Q53XD4|uniprotkb:Q9V9D2|intact:EBI-3405892|ensemblmetazoa:FBpp0085483|ensemblmetazoa:FBpp0085484|ensemblmetazoa:FBpp0085485|ensemblmetazoa:FBpp0085486 psi-mi:q9vuz0_drome(display_long)|uniprotkb:SsRbeta(gene name)|psi-mi:SsRbeta(display_short)|uniprotkb:BcDNA.LD10457(gene name synonym)|uniprotkb:SsR-beta(gene name synonym)|uniprotkb:CG5474(orf name)|uniprotkb:"BcDNA:LD10457"(gene name synonym)|uniprotkb:Dmel\CG5474(gene name synonym)|uniprotkb:"anon-EST:Liang-1.1"(gene name synonym)|uniprotkb:clone 1.1(gene name synonym)|uniprotkb:"l(3)s1939"(gene name synonym)|uniprotkb:Dmel_CG5474(orf name)|uniprotkb:Signal sequence receptor subunit beta(gene name synonym) psi-mi:vatl_drome(display_long)|uniprotkb:Vha16-1(gene name)|psi-mi:Vha16-1(display_short)|uniprotkb:VHA(gene name synonym)|uniprotkb:CG3161(orf name)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)|uniprotkb:Ductin(gene name synonym)|uniprotkb:Vha16(gene name synonym)|uniprotkb:Vacuolar H+ ATPase subunit 16-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109315|imex:IM-9552-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524103.2|flybase:FBgn0011016|ensemblmetazoa:FBgn0011016(gene)|ensemblmetazoa:FBtr0075453(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008856(Translocon-associated beta) refseq:NP_476801.1|refseq:NP_724474.1|refseq:NP_724475.1|refseq:NP_724476.1|flybase:FBgn0262736|dip:DIP-19390N|ensemblmetazoa:FBgn0262736(gene)|ensemblmetazoa:FBtr0086150(transcript)|ensemblmetazoa:FBtr0086151(transcript)|ensemblmetazoa:FBtr0086152(transcript)|ensemblmetazoa:FBtr0086153(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0033227"(dsRNA transport)|go:"GO:0045169"(fusome)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|reactome:R-DME-1222556|reactome:R-DME-6798695|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LunHRXbSqfZ95U/bJPwMAxUK3l07227 rogid:uxgicWAlJCbsWVC4WNdmaEtY1Ck7227 intact-crc:07A391AAAC171A90|rigid:yOrFzX/nE/pMNhohcNAaSBeVBh8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWC3 uniprotkb:Q7JVY0 intact:EBI-2109329|ensemblmetazoa:FBpp0074575 intact:EBI-102727|intact:EBI-2109323|ensemblmetazoa:FBpp0085526|ensemblmetazoa:FBpp0085527|ensemblmetazoa:FBpp0089194 psi-mi:q9vwc3_drome(display_long)|uniprotkb:CG11942(orf name)|uniprotkb:SkpE(gene name)|psi-mi:SkpE(display_short)|uniprotkb:skpE(gene name synonym)|uniprotkb:Dmel_CG11942(orf name)|uniprotkb:Dmel\CG11942(gene name synonym)|uniprotkb:Skp(gene name synonym) psi-mi:q7jvy0_drome(display_long)|uniprotkb:coro(gene name)|psi-mi:coro(display_short)|uniprotkb:Dmel\CG9446(gene name synonym)|uniprotkb:"l(2)k08011"(gene name synonym)|uniprotkb:CG9446(orf name)|uniprotkb:Dmel_CG9446(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109334|imex:IM-9552-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608359.1|flybase:FBgn0031074|ensemblmetazoa:FBgn0031074(gene)|ensemblmetazoa:FBtr0074806(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296 refseq:NP_610242.1|refseq:NP_724509.1|refseq:NP_995753.1|flybase:FBgn0265935|ensemblmetazoa:FBtr0086207(transcript)|ensemblmetazoa:FBtr0086208(transcript)|ensemblmetazoa:FBtr0086209(transcript)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0050832"(defense response to fungus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|ensemblmetazoa:FBgn0265935(gene) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YEd3aJ+3gYv+3VwcM3ewj1R2AUQ7227 rogid:s2diIF/MH53Rwt9YUgMaSw2M29c7227 intact-crc:76807105C573C8AB|rigid:s2Pv8uLv1qHGVbF9PLGvfi7vv6c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P54399 uniprotkb:E4NKJ7 intact:EBI-123796|uniprotkb:Q9VUL7|uniprotkb:Q53YH5|uniprotkb:Q86PE2|uniprotkb:Q8IQL8|ensemblmetazoa:FBpp0075401|ensemblmetazoa:FBpp0312224 intact:EBI-2109097|ensemblmetazoa:FBpp0071844 psi-mi:pdi_drome(display_long)|uniprotkb:Pdi(gene name)|psi-mi:Pdi(display_short)|uniprotkb:CG6988(orf name) psi-mi:e4nkj7_drome(display_long)|uniprotkb:CG2852-RA(gene name)|psi-mi:CG2852-RA(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109349|imex:IM-9552-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524079.1|refseq:NP_001287070.1|ensemblmetazoa:FBgn0286818(gene)|ensemblmetazoa:FBtr0075648(transcript)|ensemblmetazoa:FBtr0346644(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045169"(fusome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-DME-381426|reactome:R-DME-5358346|reactome:R-DME-8957275|dip:DIP-21766N|flybase:FBgn0286818 interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|ensemblmetazoa:FBgn0034753(gene)|ensemblmetazoa:FBtr0071933(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:5WvkcBmjcDkzw5HGvxX9J30oLL47227 rogid:3aIBAqr3Fyg0C5AlSkwGpkjAE4c7227 intact-crc:9FE96FDBF97C1EBB|rigid:UcrC2ZfRk/U483sgOJ/DPdAwaNA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P21914 uniprotkb:Q0E8E8 intact:EBI-136047|uniprotkb:Q9V9A0|ensemblmetazoa:FBpp0085489 intact:EBI-141739|ensemblmetazoa:FBpp0075461|ensemblmetazoa:FBpp0075462|ensemblmetazoa:FBpp0300819|intact:EBI-2108566 psi-mi:sdhb_drome(display_long)|uniprotkb:SdhB(gene name)|psi-mi:SdhB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:CG3283(orf name)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym) psi-mi:q0e8e8_drome(display_long)|uniprotkb:Mpcp2(gene name)|psi-mi:Mpcp2(display_short)|uniprotkb:Dmel\CG4994(gene name synonym)|uniprotkb:MPCP(gene name synonym)|uniprotkb:Mcpc(gene name synonym)|uniprotkb:Mpcp(gene name synonym)|uniprotkb:Mpcp-RA(gene name synonym)|uniprotkb:PpsM(gene name synonym)|uniprotkb:"l(3)00564"(gene name synonym)|uniprotkb:DmPiC2(gene name synonym)|uniprotkb:mpcp(gene name synonym)|uniprotkb:CG4994(orf name)|uniprotkb:Dmel_CG4994(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109344|imex:IM-9552-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-DME-71403|refseq:NP_477101.1|flybase:FBgn0014028|ensemblmetazoa:FBgn0014028(gene)|ensemblmetazoa:FBtr0086156(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0009055"(electron transfer activity)|dip:DIP-20115N refseq:NP_524069.2|refseq:NP_729978.1|flybase:FBgn0026409|refseq:NP_001246757.1|ensemblmetazoa:FBgn0026409(gene)|ensemblmetazoa:FBtr0075718(transcript)|ensemblmetazoa:FBtr0075719(transcript)|ensemblmetazoa:FBtr0308595(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xtvWH/0V/SoBZ6cfsHV7vnjugKw7227 rogid:1vbheQY3Za1uaFww6BBY9iqCj+Y7227 intact-crc:BB7630526763D85F|rigid:kEPz/wwlWYAz4/BAr2pqNFdRUK8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SXG7 uniprotkb:Q05547 intact:EBI-118303|uniprotkb:Q9VQZ9|ensemblmetazoa:FBpp0077144 intact:EBI-157144|uniprotkb:Q9VXW0|ensemblmetazoa:FBpp0073834 psi-mi:q8sxg7_drome(display_long)|uniprotkb:Secp43(gene name)|psi-mi:Secp43(display_short)|uniprotkb:Dmel\CG15440(gene name synonym)|uniprotkb:cg15440(gene name synonym)|uniprotkb:tRNA selenocysteine-associated protein 1(gene name synonym)|uniprotkb:CG15440(orf name)|uniprotkb:Dmel_CG15440(orf name) psi-mi:pp13_drome(display_long)|uniprotkb:Pp1-13C(gene name)|psi-mi:Pp1-13C(display_short)|uniprotkb:CG9156(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109339|imex:IM-9552-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608837.2|flybase:FBgn0031607|ensemblmetazoa:FBgn0031607(gene)|ensemblmetazoa:FBtr0077454(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034510|interpro:IPR035979|interpro:IPR041085 refseq:NP_524921.1|flybase:FBgn0003132|dip:DIP-23332N|ensemblmetazoa:FBgn0003132(gene)|ensemblmetazoa:FBtr0074017(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046692"(sperm competition)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|reactome:R-DME-538898 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WBXfxCWvCmLGxGUyM1ldkyZhvug7227 rogid:3Asj1ctAhmzU9rsIbIwDdRufFdc7227 intact-crc:8C3C8BC41CFA5A2A|rigid:WQ/gRpKOqBggmQgZsUogkisl6e8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q27884 uniprotkb:O77430 intact:EBI-99228|uniprotkb:Q5BIJ4|uniprotkb:Q8MRZ7|uniprotkb:Q9W3Z8|ensemblmetazoa:FBpp0070883|ensemblmetazoa:FBpp0303847|ensemblmetazoa:FBpp0303848|ensemblmetazoa:FBpp0303849 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:ppp6_drome(display_long)|uniprotkb:PpV(gene name)|psi-mi:PpV(display_short)|uniprotkb:PPPV6A(gene name synonym)|uniprotkb:CG12217(orf name)|uniprotkb:Phosphatase V(gene name synonym) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109354|imex:IM-9552-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511061.1|flybase:FBgn0003139|refseq:NP_001259272.1|refseq:NP_001259273.1|refseq:NP_001259274.1|ensemblmetazoa:FBgn0003139(gene)|ensemblmetazoa:FBtr0070921(transcript)|ensemblmetazoa:FBtr0331430(transcript)|ensemblmetazoa:FBtr0331431(transcript)|ensemblmetazoa:FBtr0331432(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|dip:DIP-20494N refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:EO7pNWevzqdO1j5I6OVUdRjjWCs7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 intact-crc:25E892F14DCCC490|rigid:LIjXCGlRcv4Wg4PL4qUv6+QEcRA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q9VTM4 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-179352|ensemblmetazoa:FBpp0075855|ensemblmetazoa:FBpp0075856|ensemblmetazoa:FBpp0075857|ensemblmetazoa:FBpp0075858|ensemblmetazoa:FBpp0075859 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q9vtm4_drome(display_long)|uniprotkb:Dmel\CG11658(gene name)|psi-mi:Dmel\CG11658(display_short)|uniprotkb:FBXO12(gene name synonym)|uniprotkb:anon-WO0118547.413(gene name synonym)|uniprotkb:CG11658(orf name)|uniprotkb:Dmel_CG11658(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109359|imex:IM-9552-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_648498.1|refseq:NP_996058.1|refseq:NP_996059.1|refseq:NP_996060.1|refseq:NP_996061.1|flybase:FBgn0036196|ensemblmetazoa:FBgn0036196(gene)|ensemblmetazoa:FBtr0076124(transcript)|ensemblmetazoa:FBtr0076125(transcript)|ensemblmetazoa:FBtr0076126(transcript)|ensemblmetazoa:FBtr0076127(transcript)|ensemblmetazoa:FBtr0076128(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR040394|reactome:R-DME-8951664|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:nnZlq2cwJWByucq/7KA/J39AaRY7227 intact-crc:3E0210F057DAB42A|rigid:O7H2E8lf8kzoXrnihxO2ZoVC39M false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q9VFN3 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-2109367|ensemblmetazoa:FBpp0082374 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q9vfn3_drome(display_long)|uniprotkb:CG12402-RA(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:CG12402(orf name)|uniprotkb:Dmel_CG12402(orf name)|uniprotkb:Dmel\CG12402(gene name)|psi-mi:Dmel\CG12402(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109364|imex:IM-9552-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_650335.1|flybase:FBgn0038202|ensemblmetazoa:FBgn0038202(gene)|ensemblmetazoa:FBtr0082914(transcript)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:bkCh2yfnUHfdVCu/lZZH7KQKdpo7227 intact-crc:72C57F57C90D050E|rigid:vv3WbewuBqMiZj7GMVrZWf5R2PI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V9R2 uniprotkb:Q7JWD6 intact:EBI-149875|uniprotkb:Q95RE8|ensemblmetazoa:FBpp0085254|ensemblmetazoa:FBpp0085255 intact:EBI-162306|intact:EBI-2108668|ensemblmetazoa:FBpp0085724|ensemblmetazoa:FBpp0085725 psi-mi:q9v9r2_drome(display_long)|uniprotkb:Cul2(gene name)|psi-mi:Cul2(display_short)|uniprotkb:Cul-2(gene name synonym)|uniprotkb:cul-2(gene name synonym)|uniprotkb:CUL2(gene name synonym)|uniprotkb:Cullin2(gene name synonym)|uniprotkb:DMcul-2(gene name synonym)|uniprotkb:Dmel\CG1512(gene name synonym)|uniprotkb:cul2(gene name synonym)|uniprotkb:dCul2(gene name synonym)|uniprotkb:"l(2)02074"(gene name synonym)|uniprotkb:Dmel_CG1512(orf name)|uniprotkb:CG1512(orf name) psi-mi:q7jwd6_drome(display_long)|uniprotkb:EloC(gene name)|psi-mi:EloC(display_short)|uniprotkb:Elongin-C(gene name synonym)|uniprotkb:"BcDNA:RH71704"(gene name synonym)|uniprotkb:Dmel\CG9291(gene name synonym)|uniprotkb:ElonginC(gene name synonym)|uniprotkb:dElongin C(gene name synonym)|uniprotkb:"l(2)SH1299"(gene name synonym)|uniprotkb:"l(2)SH1520"(gene name synonym)|uniprotkb:"l(2)SH2 1520"(gene name synonym)|uniprotkb:CG9291(orf name)|uniprotkb:Dmel_CG9291(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109372|imex:IM-9552-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610117.1|refseq:NP_724352.1|flybase:FBgn0032956|ensemblmetazoa:FBgn0032956(gene)|ensemblmetazoa:FBtr0085899(transcript)|ensemblmetazoa:FBtr0085900(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0007281"(germ cell development)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016032"(viral process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-1234176|reactome:R-DME-8951664|reactome:R-DME-983168 refseq:NP_523794.1|refseq:NP_725894.1|ensemblmetazoa:FBgn0266711(gene)|ensemblmetazoa:FBtr0086540(transcript)|ensemblmetazoa:FBtr0086541(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0016032"(viral process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-DME-112382|reactome:R-DME-1234176|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-75955|reactome:R-DME-8951664|reactome:R-DME-983168|flybase:FBgn0266711 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uAJ4b/DFGP8CUQ+8upYEv79XoCg7227 rogid:U68k7tnCTTZCUIir5Iu+zAtyXU47227 intact-crc:68276AEEF23ABAF6|rigid:5ntf+AZC1WDVmHe8Z8dbWEQXlx8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P02572 uniprotkb:Q24547 intact:EBI-110368|uniprotkb:Q24228|uniprotkb:Q540X3|uniprotkb:Q9V9J4|ensemblmetazoa:FBpp0085365 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 psi-mi:act2_drome(display_long)|uniprotkb:Act42A(gene name)|psi-mi:Act42A(display_short)|uniprotkb:CG12051(orf name) psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109387|imex:IM-9552-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523625.1|flybase:FBgn0000043|dip:DIP-20355N|ensemblmetazoa:FBgn0000043(gene)|ensemblmetazoa:FBtr0086029(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0035060"(brahma complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129 refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YeeXgsuRY2BQ3DVxG7MuVmol+bo7227 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 intact-crc:F91CE8326FD3B5C9|rigid:52N/aHsE8cdsMan7tGmT27fOBK0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P18489 uniprotkb:Q24547 intact:EBI-497912|uniprotkb:Q8MKX1|uniprotkb:Q9V5I6|uniprotkb:Q3HKB4|uniprotkb:B7YZD5|uniprotkb:B7YZD6|ensemblmetazoa:FBpp0271782 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 psi-mi:syb_drome(display_long)|uniprotkb:Syb(gene name)|psi-mi:Syb(display_short)|uniprotkb:CG12210(orf name) psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109377|imex:IM-9552-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286278.1|refseq:NP_001137633.1|refseq:NP_001137634.1|refseq:NP_523680.1|refseq:NP_724906.1|flybase:FBgn0003660|ensemblmetazoa:FBgn0003660(gene)|ensemblmetazoa:FBtr0273274(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0043005"(neuron projection)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-6811440|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-888590|reactome:R-DME-8980692|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013405|reactome:R-DME-9013406|reactome:R-DME-9013407|reactome:R-DME-9035034|reactome:R-DME-9609523 refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0GVct78wgjr8E88ZYPr03wY7yr87227 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 intact-crc:F4E24EE0C4F4259B|rigid:e0x0A3/0WRdLYdD3ESw9B7y+8XQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24547 uniprotkb:Q23983 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109382|imex:IM-9552-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:16D48EBF3CDBDC89|rigid:oYwyOJI+zGbuT2Owm9puk6noEj0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KMP8 uniprotkb:Q9V3Z4 intact:EBI-151692|intact:EBI-2109416|ensemblmetazoa:FBpp0083860|ensemblmetazoa:FBpp0083861 intact:EBI-194156|ensemblmetazoa:FBpp0078278 psi-mi:q7kmp8_drome(display_long)|uniprotkb:Rpn9(gene name)|psi-mi:Rpn9(display_short)|uniprotkb:06(gene name synonym)|uniprotkb:0718(gene name synonym)|uniprotkb:718(gene name synonym)|uniprotkb:CT28749(gene name synonym)|uniprotkb:Dmel\CG10230(gene name synonym)|uniprotkb:PSMD13(gene name synonym)|uniprotkb:Rpn4(gene name synonym)|uniprotkb:Rpn94(gene name synonym)|uniprotkb:S11(gene name synonym)|uniprotkb:"l(3)S071806"(gene name synonym)|uniprotkb:"l(3)S071806b"(gene name synonym)|uniprotkb:p39A(gene name synonym)|uniprotkb:rpn9(gene name synonym)|uniprotkb:Dmel_CG10230(orf name)|uniprotkb:CG10230(orf name)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym) psi-mi:q9v3z4_drome(display_long)|uniprotkb:Rpn5(gene name)|psi-mi:Rpn5(display_short)|uniprotkb:Dmel\CG1100(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:rpn5(gene name synonym)|uniprotkb:Dmel_CG1100(orf name)|uniprotkb:CG1100(orf name)|uniprotkb:RPN5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109413|imex:IM-9552-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651177.1|refseq:NP_732899.1|flybase:FBgn0028691|ensemblmetazoa:FBgn0028691(gene)|ensemblmetazoa:FBtr0084469(transcript)|ensemblmetazoa:FBtr0084470(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_649588.1|flybase:FBgn0028690|ensemblmetazoa:FBgn0028690(gene)|ensemblmetazoa:FBtr0078629(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hEc3E83aGFg8Gw9MZx51ViGA3Qk7227 rogid:azbJhVBPfCYPje4TfFZ0G3XFh0s7227 intact-crc:E000CC0435DA4A60|rigid:OEHx4es3PB0vRJmx6J6SuWWBJVU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8MRB5 uniprotkb:Q8MYV0 intact:EBI-2109399 intact:EBI-2109392 psi-mi:q8mrb5_drome(display_long)|uniprotkb:CG6738(orf name) psi-mi:q8myv0_drome(display_long)|uniprotkb:Gabat(gene name)|psi-mi:Gabat(display_short)|uniprotkb:GABA aminotransferase(gene name synonym)|uniprotkb:Gamma-amino-N-butyrate transaminase(gene name synonym)|uniprotkb:L-AIBAT(gene name synonym)|uniprotkb:CG7433(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109396|imex:IM-9552-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0039053|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006520"(cellular amino acid metabolic process)|interpro:IPR002933(Peptidase M20)|interpro:IPR010159(N-acyl-L-amino-acid amidohydrolase)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR036264 flybase:FBgn0036927|go:"GO:0003867"(4-aminobutyrate transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034386"("4-aminobutyrate:2-oxoglutarate transaminase activity")|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0047298"("(S)-3-amino-2-methylpropionate transaminase activity")|go:"GO:2000211"(regulation of glutamate metabolic process)|interpro:IPR004631(4-aminobutyrate aminotransferase, eukaryotic)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:DEpoLltTBU4wN6AQ3NXbpEpDWeo7227 rogid:6B5Fl4Dhj0UzXfI84ZSEwDelj707227 intact-crc:A3140F8C0E89EFC0|rigid:zRL0EPxYvu/lNvGW1Wkgqt+l8dY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q86R99 uniprotkb:P48462 intact:EBI-2109404 intact:EBI-869621|uniprotkb:Q9W2V5|ensemblmetazoa:FBpp0071382|ensemblmetazoa:FBpp0305497 psi-mi:q86r99_drome(display_long)|uniprotkb:Mbs(gene name)|psi-mi:Mbs(display_short)|uniprotkb:CG32156(orf name) psi-mi:pp1b_drome(display_long)|uniprotkb:Protein flap wing(gene name synonym)|uniprotkb:flw(gene name)|psi-mi:flw(display_short)|uniprotkb:PP1-9C(gene name synonym)|uniprotkb:PP1-BETA-9C(gene name synonym)|uniprotkb:CG2096(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109408|imex:IM-9552-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005536|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007391"(dorsal closure)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030725"(germline ring canal formation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770 refseq:NP_524738.1|flybase:FBgn0000711|refseq:NP_001259407.1|ensemblmetazoa:FBgn0000711(gene)|ensemblmetazoa:FBtr0071447(transcript)|ensemblmetazoa:FBtr0333305(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1905330"(regulation of morphogenesis of an epithelium)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|reactome:R-DME-2565942|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|reactome:R-DME-5625740|reactome:R-DME-5627123 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:AD3NoY9NCh8cIJTpNyDQcQkuL/A7227 rogid:PZSfwmpwqFs81zLVfparcg1xIZY7227 intact-crc:DA26600D11F03DE9|rigid:bEmNDAJpo+eYIeJ3iuSr8mdYeew false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V3H2 uniprotkb:Q7K148 intact:EBI-178674|uniprotkb:Q9NIU3|ensemblmetazoa:FBpp0078664 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 psi-mi:psde_drome(display_long)|uniprotkb:Rpn11(gene name)|psi-mi:Rpn11(display_short)|uniprotkb:CG18174(orf name)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym)|uniprotkb:26S proteasome regulatory complex subunit p37B(gene name synonym)|uniprotkb:Yippee-interacting protein 5(gene name synonym)|uniprotkb:yip5(gene name synonym) psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109427|imex:IM-9552-464 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608905.1|flybase:FBgn0028694|ensemblmetazoa:FBgn0028694(gene)|ensemblmetazoa:FBtr0079027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5689901|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7tJj3IGZzTi2DJujVlgT30KGpow7227 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 intact-crc:ACAFF7F90751C35C|rigid:S9BAMrahD6mv18sRUcOFoC+ZVx8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KMP8 uniprotkb:P26270 intact:EBI-151692|intact:EBI-2109416|ensemblmetazoa:FBpp0083860|ensemblmetazoa:FBpp0083861 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 psi-mi:q7kmp8_drome(display_long)|uniprotkb:Rpn9(gene name)|psi-mi:Rpn9(display_short)|uniprotkb:06(gene name synonym)|uniprotkb:0718(gene name synonym)|uniprotkb:718(gene name synonym)|uniprotkb:CT28749(gene name synonym)|uniprotkb:Dmel\CG10230(gene name synonym)|uniprotkb:PSMD13(gene name synonym)|uniprotkb:Rpn4(gene name synonym)|uniprotkb:Rpn94(gene name synonym)|uniprotkb:S11(gene name synonym)|uniprotkb:"l(3)S071806"(gene name synonym)|uniprotkb:"l(3)S071806b"(gene name synonym)|uniprotkb:p39A(gene name synonym)|uniprotkb:rpn9(gene name synonym)|uniprotkb:Dmel_CG10230(orf name)|uniprotkb:CG10230(orf name)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym) psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109422|imex:IM-9552-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651177.1|refseq:NP_732899.1|flybase:FBgn0028691|ensemblmetazoa:FBgn0028691(gene)|ensemblmetazoa:FBtr0084469(transcript)|ensemblmetazoa:FBtr0084470(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hEc3E83aGFg8Gw9MZx51ViGA3Qk7227 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 intact-crc:7018C01D20A245BB|rigid:oIjWlrnLpTkdcqW+OlmW2+F73z0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P26270 uniprotkb:Q9V3H2 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 intact:EBI-178674|uniprotkb:Q9NIU3|ensemblmetazoa:FBpp0078664 psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:psde_drome(display_long)|uniprotkb:Rpn11(gene name)|psi-mi:Rpn11(display_short)|uniprotkb:CG18174(orf name)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym)|uniprotkb:26S proteasome regulatory complex subunit p37B(gene name synonym)|uniprotkb:Yippee-interacting protein 5(gene name synonym)|uniprotkb:yip5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109432|imex:IM-9552-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_608905.1|flybase:FBgn0028694|ensemblmetazoa:FBgn0028694(gene)|ensemblmetazoa:FBtr0079027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5689901|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 rogid:7tJj3IGZzTi2DJujVlgT30KGpow7227 intact-crc:096D1C1629AA210D|rigid:GXCmD4TCzDj/Bb7A8wILV4m9zGg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V3D0 uniprotkb:Q8IHE3 intact:EBI-2109286|ensemblmetazoa:FBpp0080401 intact:EBI-2109269 psi-mi:q9v3d0_drome(display_long)|uniprotkb:CG5818(orf name)|uniprotkb:mRpL4(gene name)|psi-mi:mRpL4(display_short)|uniprotkb:"BG:DS02740.17"(gene name synonym)|uniprotkb:Dmel\CG5818(gene name synonym)|uniprotkb:L4(gene name synonym)|uniprotkb:Rpl4(gene name synonym)|uniprotkb:"l(2)35Fe"(gene name synonym)|uniprotkb:"l(2)k14608"(gene name synonym)|uniprotkb:l35Fe(gene name synonym)|uniprotkb:mrpL4(gene name synonym)|uniprotkb:Dmel_CG5818(orf name) psi-mi:q8ihe3_drome(display_long)|uniprotkb:CG11779(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109447|imex:IM-9552-466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524939.1|flybase:FBgn0001995|ensemblmetazoa:FBgn0001995(gene)|ensemblmetazoa:FBtr0080843(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|reactome:R-DME-5389840|reactome:R-DME-5419276 flybase:FBgn0038683|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0051087"(chaperone binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR017303(Import inner membrane translocase, TIM44 subunit, mitochondria)|interpro:IPR032710|interpro:IPR039544 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PZQEwLbpRvJHWWgpF+w75s3pU5o7227 rogid:gpHo7+Gc8+ktDHkO7oux2/nnMm07227 intact-crc:DCDC6B4BF0127F7C|rigid:rc6mUdihyDM7lpktvvxCtNMz8tc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O44382 uniprotkb:Q27884 intact:EBI-869364 intact:EBI-99228|uniprotkb:Q5BIJ4|uniprotkb:Q8MRZ7|uniprotkb:Q9W3Z8|ensemblmetazoa:FBpp0070883|ensemblmetazoa:FBpp0303847|ensemblmetazoa:FBpp0303848|ensemblmetazoa:FBpp0303849 psi-mi:o44382_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:slimb(gene name synonym)|uniprotkb:CG3412(orf name) psi-mi:ppp6_drome(display_long)|uniprotkb:PpV(gene name)|psi-mi:PpV(display_short)|uniprotkb:PPPV6A(gene name synonym)|uniprotkb:CG12217(orf name)|uniprotkb:Phosphatase V(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109442|imex:IM-9552-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-432524 refseq:NP_511061.1|flybase:FBgn0003139|refseq:NP_001259272.1|refseq:NP_001259273.1|refseq:NP_001259274.1|ensemblmetazoa:FBgn0003139(gene)|ensemblmetazoa:FBtr0070921(transcript)|ensemblmetazoa:FBtr0331430(transcript)|ensemblmetazoa:FBtr0331431(transcript)|ensemblmetazoa:FBtr0331432(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|dip:DIP-20494N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hKsZL6X4sxi/Zu4RDHlAV5IoZ2o7227 rogid:EO7pNWevzqdO1j5I6OVUdRjjWCs7227 intact-crc:F6ED5D8671D6A007|rigid:wwr4XLRP82E7jdfwlT5JhbTVH+Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:Q7K148 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109452|imex:IM-9552-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 intact-crc:9A6798975B6F38CC|rigid:q5f9pQFBF1IOY+VHbh/pa6NPt7s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V3H2 uniprotkb:A5XCL5 intact:EBI-178674|uniprotkb:Q9NIU3|ensemblmetazoa:FBpp0078664 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 psi-mi:psde_drome(display_long)|uniprotkb:Rpn11(gene name)|psi-mi:Rpn11(display_short)|uniprotkb:CG18174(orf name)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym)|uniprotkb:26S proteasome regulatory complex subunit p37B(gene name synonym)|uniprotkb:Yippee-interacting protein 5(gene name synonym)|uniprotkb:yip5(gene name synonym) psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109437|imex:IM-9552-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608905.1|flybase:FBgn0028694|ensemblmetazoa:FBgn0028694(gene)|ensemblmetazoa:FBtr0079027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5689901|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7tJj3IGZzTi2DJujVlgT30KGpow7227 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 intact-crc:C2C29D58005A90D0|rigid:T+r1lqgs8FjO0lK6qi1Rjg1iAeA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P18053 uniprotkb:P40301 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109462|imex:IM-9552-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:5743CF5DA46CE9DF|rigid:XvopFFNF4GMNqqsx7tazvkm0l2A false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:P12881 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109457|imex:IM-9552-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 intact-crc:7232E4A9DE70E7D6|rigid:BoXl2S51MAcD5dE466cELulVUZ8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SYV4 uniprotkb:Q9VUC3 intact:EBI-2109467|ensemblmetazoa:FBpp0083659 intact:EBI-1627788|ensemblmetazoa:FBpp0075516|ensemblmetazoa:FBpp0291625 psi-mi:q8syv4_drome(display_long)|uniprotkb:CG6937(orf name) psi-mi:q9vuc3_drome(display_long)|uniprotkb:Dmel\CG6833(gene name)|psi-mi:Dmel\CG6833(display_short)|uniprotkb:REXO4(gene name synonym)|uniprotkb:CG6833(orf name)|uniprotkb:Dmel_CG6833(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109470|imex:IM-9552-468 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0038989|ensemblmetazoa:FBgn0038989(gene)|ensemblmetazoa:FBtr0084266(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 refseq:NP_001189105.1|refseq:NP_648689.1|flybase:FBgn0036405|ensemblmetazoa:FBgn0036405(gene)|ensemblmetazoa:FBtr0075774(transcript)|ensemblmetazoa:FBtr0302433(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|interpro:IPR037431 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:a1BqVkiifc2IK9KTlYoAhct/T1Y7227 rogid:ronrdK7nsTsabdivP66uD13RfSg7227 intact-crc:8E522CFAB9F39E35|rigid:HZap036hLanMo5+UhWS7p/2Xj10 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q5BI79 uniprotkb:P31007 intact:EBI-2109478|ensemblmetazoa:FBpp0071422 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 psi-mi:q5bi79_drome(display_long)|uniprotkb:CG32677(orf name)|uniprotkb:X11Lbeta(gene name)|psi-mi:X11Lbeta(display_short) psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109475|imex:IM-9552-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0052677|ensemblmetazoa:FBgn0052677(gene)|ensemblmetazoa:FBtr0071493(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043197"(dendritic spine)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034 refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xSxONimToR5nj5KLt8CxQQmCe7Q7227 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 intact-crc:B528A527FE881157|rigid:QnhNMUnawQBz3fuCyV/TVTiyk08 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9NFT2 uniprotkb:Q9V4N3 intact:EBI-2109485 intact:EBI-93553|uniprotkb:Q6AWQ2|uniprotkb:Q8IH75|uniprotkb:Q9I7E0|ensemblmetazoa:FBpp0087979 psi-mi:q9nft2_drome(display_long)|uniprotkb:fad(gene name synonym)|uniprotkb:Fad2(gene name)|psi-mi:Fad2(display_short)|uniprotkb:CG7923(orf name) psi-mi:cyb5_drome(display_long)|uniprotkb:Cyt-b5(gene name)|psi-mi:Cyt-b5(display_short)|uniprotkb:CG2140(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109490|imex:IM-9552-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0029172|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0007619"(courtship behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042810"(pheromone metabolic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR015876(Fatty acid desaturase, type 1, core) refseq:NP_610294.1|refseq:NP_724575.1|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0006979"(response to oxidative stress)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|reactome:R-DME-196836|reactome:R-DME-211945|reactome:R-DME-9609523|go:"GO:0009055"(electron transfer activity)|go:"GO:0012505"(endomembrane system)|ensemblmetazoa:FBgn0264294(gene)|ensemblmetazoa:FBtr0088905(transcript)|flybase:FBgn0264294|dip:DIP-22488N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:4PFBEMwXykwcMoPDR46kFW8elbw7227 rogid:fQwbjA49gBTICdp3qyzr8Y0PqdM7227 intact-crc:44E46BA068613283|rigid:4oncLRjREklALewrRNZMqXRDzq0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VRJ4 uniprotkb:Q9W2M2 intact:EBI-2109495|ensemblmetazoa:FBpp0076882 intact:EBI-261090|uniprotkb:Q0E903|uniprotkb:Q0E904|uniprotkb:Q7YWL2|uniprotkb:Q961P0|uniprotkb:Q9W2M1|uniprotkb:Q9W2M3|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 psi-mi:q9vrj4_drome(display_long)|uniprotkb:Dhrs4(gene name)|psi-mi:Dhrs4(display_short)|uniprotkb:DHRS4(gene name synonym)|uniprotkb:Dmel\CG10672(gene name synonym)|uniprotkb:CG10672(orf name)|uniprotkb:Dmel_CG10672(orf name) psi-mi:trea_drome(display_long)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:CG9364(orf name)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109498|imex:IM-9552-470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_647946.1|flybase:FBgn0035588|ensemblmetazoa:FBgn0035588(gene)|ensemblmetazoa:FBtr0077179(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005777"(peroxisome)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-DME-5365859|reactome:R-DME-9033241 refseq:NP_524821.1|refseq:NP_726023.1|refseq:NP_726024.1|refseq:NP_726025.1|refseq:NP_726026.1|refseq:NP_726027.1|flybase:FBgn0003748|refseq:NP_001261115.1|dip:DIP-23202N|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript)|go:"GO:0004555"(alpha,alpha-trehalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005991"(trehalose metabolic process)|go:"GO:0005993"(trehalose catabolic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR001661(Glycoside hydrolase, family 37)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR018232 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:JIo6DRNtCgSazMU6uqd7EWTsWNM7227 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 intact-crc:7749F40DEA9ECC21|rigid:JYuj/WDbDLPjE9elYHiC4lH6R5Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8MRV7 uniprotkb:Q29QQ9 intact:EBI-2109296 intact:EBI-123608|intact:EBI-2109181|ensemblmetazoa:FBpp0086348 psi-mi:q8mrv7_drome(display_long)|uniprotkb:mRpL3(gene name)|psi-mi:mRpL3(display_short)|uniprotkb:CG8288(orf name) psi-mi:q29qq9_drome(display_long)|uniprotkb:Rrp42(gene name)|psi-mi:Rrp42(display_short)|uniprotkb:Dmel\CG8395(gene name synonym)|uniprotkb:"anon-EST:Posey140"(gene name synonym)|uniprotkb:"anon-EST:Posey187"(gene name synonym)|uniprotkb:dRrp42(gene name synonym)|uniprotkb:CG8395(orf name)|uniprotkb:Dmel_CG8395(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109508|imex:IM-9552-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0030686|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019927 refseq:NP_725517.2|flybase:FBgn0034065|ensemblmetazoa:FBgn0034065(gene)|ensemblmetazoa:FBtr0087206(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|reactome:R-DME-429958|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-6791226 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:1cLwoHe3+eYgQTDdI3SfOlIuoFs7227 rogid:kXWZAL7cUNBc5VEfLubZyh6DJqQ7227 intact-crc:2C2C0E8CA500B32C|rigid:uhRuWwcbgjCEIkQRrzN9XXV2CgI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K148 uniprotkb:P40301 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109503|imex:IM-9552-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:A643FFF3098567A2|rigid:DQo7JqAhOLCmEbuuCpOoU61MznM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JWD6 uniprotkb:O44226 intact:EBI-162306|intact:EBI-2108668|ensemblmetazoa:FBpp0085724|ensemblmetazoa:FBpp0085725 intact:EBI-157843|ensemblmetazoa:FBpp0083354 psi-mi:q7jwd6_drome(display_long)|uniprotkb:EloC(gene name)|psi-mi:EloC(display_short)|uniprotkb:Elongin-C(gene name synonym)|uniprotkb:"BcDNA:RH71704"(gene name synonym)|uniprotkb:Dmel\CG9291(gene name synonym)|uniprotkb:ElonginC(gene name synonym)|uniprotkb:dElongin C(gene name synonym)|uniprotkb:"l(2)SH1299"(gene name synonym)|uniprotkb:"l(2)SH1520"(gene name synonym)|uniprotkb:"l(2)SH2 1520"(gene name synonym)|uniprotkb:CG9291(orf name)|uniprotkb:Dmel_CG9291(orf name) psi-mi:o44226_drome(display_long)|uniprotkb:EloB(gene name)|psi-mi:EloB(display_short)|uniprotkb:Elongin-B(gene name synonym)|uniprotkb:Dmel_CG4204(orf name)|uniprotkb:CG4204(orf name)|uniprotkb:Dmel\CG4204(gene name synonym)|uniprotkb:Elo-B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109513|imex:IM-9552-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523794.1|refseq:NP_725894.1|ensemblmetazoa:FBgn0266711(gene)|ensemblmetazoa:FBtr0086540(transcript)|ensemblmetazoa:FBtr0086541(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0016032"(viral process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-DME-112382|reactome:R-DME-1234176|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-75955|reactome:R-DME-8951664|reactome:R-DME-983168|flybase:FBgn0266711 ensemblmetazoa:FBgn0023212(gene)|ensemblmetazoa:FBtr0083947(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0016032"(viral process)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|reactome:R-DME-112382|reactome:R-DME-1234176|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-75955|reactome:R-DME-8951664|reactome:R-DME-983168|refseq:NP_524416.1|flybase:FBgn0023212|dip:DIP-19644N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:U68k7tnCTTZCUIir5Iu+zAtyXU47227 rogid:U2pRVyuDAYM2wVLhZrtz7UF+TAM7227 intact-crc:BF86A413A9CC38FF|rigid:ESXWvj9jp76SWXpv4ToW/lOrbeM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31007 uniprotkb:Q8WS23 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-870047 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:q8ws23_drome(display_long)|uniprotkb:rols(gene name)|psi-mi:rols(display_short)|uniprotkb:rols6(gene name synonym)|uniprotkb:CG32096(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109518|imex:IM-9552-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N flybase:FBgn0041096|go:"GO:0005737"(cytoplasm)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016740"(transferase activity)|go:"GO:0030018"(Z disc)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:liZ6VBX2yzld6LPOkXv5Ro19rKY7227 intact-crc:D4FC38BAA080E8AE|rigid:Um8QoPK6MQiHK65Ec2yL5XhxWII false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23380 uniprotkb:Q9VFE3 intact:EBI-185634|uniprotkb:A4UZ55|uniprotkb:Q0E9N6|uniprotkb:Q53XD4|uniprotkb:Q9V9D2|intact:EBI-3405892|ensemblmetazoa:FBpp0085483|ensemblmetazoa:FBpp0085484|ensemblmetazoa:FBpp0085485|ensemblmetazoa:FBpp0085486 intact:EBI-160737|ensemblmetazoa:FBpp0082464|ensemblmetazoa:FBpp0300391 psi-mi:vatl_drome(display_long)|uniprotkb:Vha16-1(gene name)|psi-mi:Vha16-1(display_short)|uniprotkb:VHA(gene name synonym)|uniprotkb:CG3161(orf name)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)|uniprotkb:Ductin(gene name synonym)|uniprotkb:Vha16(gene name synonym)|uniprotkb:Vacuolar H+ ATPase subunit 16-1(gene name synonym) psi-mi:q9vfe3_drome(display_long)|uniprotkb:VhaPPA1-1(gene name)|psi-mi:VhaPPA1-1(display_short)|uniprotkb:Dmel\CG7007(gene name synonym)|uniprotkb:V0c''(gene name synonym)|uniprotkb:Vha26(gene name synonym)|uniprotkb:VhaPPA1(gene name synonym)|uniprotkb:vhaPPA1-1(gene name synonym)|uniprotkb:Dmel_CG7007(orf name)|uniprotkb:CG7007(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109523|imex:IM-9552-472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476801.1|refseq:NP_724474.1|refseq:NP_724475.1|refseq:NP_724476.1|flybase:FBgn0262736|dip:DIP-19390N|ensemblmetazoa:FBgn0262736(gene)|ensemblmetazoa:FBtr0086150(transcript)|ensemblmetazoa:FBtr0086151(transcript)|ensemblmetazoa:FBtr0086152(transcript)|ensemblmetazoa:FBtr0086153(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0033227"(dsRNA transport)|go:"GO:0045169"(fusome)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|reactome:R-DME-1222556|reactome:R-DME-6798695|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712 refseq:NP_652010.1|flybase:FBgn0028662|ensemblmetazoa:FBgn0028662(gene)|ensemblmetazoa:FBtr0083005(transcript)|ensemblmetazoa:FBtr0308030(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|refseq:NP_001247111.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uxgicWAlJCbsWVC4WNdmaEtY1Ck7227 rogid:ehVJ3KtyJ98C/cC0Q1GePGBi9eU7227 intact-crc:178D8759F5CA107A|rigid:WdPM4IutFSjxANeMFvURIMJGugE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q23983 uniprotkb:Q5BI25 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 intact:EBI-2109536 psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:q5bi25_drome(display_long)|uniprotkb:Syx6(gene name)|psi-mi:Syx6(display_short)|uniprotkb:CG7736(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109542|imex:IM-9552-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 flybase:FBgn0037084|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2017/03/30 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 rogid:hsRWyXsxYy8tLrP1Rl+lnuYDBH07227 intact-crc:C93ACEBC312B41DB|rigid:mAj8nZzDHjG/smB8shy5K29+x8Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W2M2 uniprotkb:A5XCL5 intact:EBI-261090|uniprotkb:Q0E903|uniprotkb:Q0E904|uniprotkb:Q7YWL2|uniprotkb:Q961P0|uniprotkb:Q9W2M1|uniprotkb:Q9W2M3|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 psi-mi:trea_drome(display_long)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:CG9364(orf name)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym) psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109547|imex:IM-9552-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524821.1|refseq:NP_726023.1|refseq:NP_726024.1|refseq:NP_726025.1|refseq:NP_726026.1|refseq:NP_726027.1|flybase:FBgn0003748|refseq:NP_001261115.1|dip:DIP-23202N|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript)|go:"GO:0004555"(alpha,alpha-trehalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005991"(trehalose metabolic process)|go:"GO:0005993"(trehalose catabolic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR001661(Glycoside hydrolase, family 37)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR018232 refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 intact-crc:0C6B784B64DC75AD|rigid:SjFaDcf/xxFqFUXh8g60sn9X2Fg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q23983 uniprotkb:Q9VZC9 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 intact:EBI-2108952|ensemblmetazoa:FBpp0073149 psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:q9vzc9_drome(display_long)|uniprotkb:Syx17(gene name)|psi-mi:Syx17(display_short)|uniprotkb:Dm Syx17(gene name synonym)|uniprotkb:DmSyx17(gene name synonym)|uniprotkb:Dmel\CG7452(gene name synonym)|uniprotkb:S17(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:syx17(gene name synonym)|uniprotkb:CG7452(orf name)|uniprotkb:Dmel_CG7452(orf name)|uniprotkb:Stx17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109528|imex:IM-9552-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 refseq:NP_523926.1|flybase:FBgn0035540|ensemblmetazoa:FBgn0035540(gene)|ensemblmetazoa:FBtr0073293(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR010989(t-SNARE)|interpro:IPR028676 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 rogid:AVwCimBFmfW0aitbEjEpGIjqZWA7227 intact-crc:4D3F409446AE88A0|rigid:8YkcmAXoeTxaZmRV+VFqawBnGPE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VZC9 uniprotkb:Q5BI25 intact:EBI-2108952|ensemblmetazoa:FBpp0073149 intact:EBI-2109536 psi-mi:q9vzc9_drome(display_long)|uniprotkb:Syx17(gene name)|psi-mi:Syx17(display_short)|uniprotkb:Dm Syx17(gene name synonym)|uniprotkb:DmSyx17(gene name synonym)|uniprotkb:Dmel\CG7452(gene name synonym)|uniprotkb:S17(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:syx17(gene name synonym)|uniprotkb:CG7452(orf name)|uniprotkb:Dmel_CG7452(orf name)|uniprotkb:Stx17(gene name synonym) psi-mi:q5bi25_drome(display_long)|uniprotkb:Syx6(gene name)|psi-mi:Syx6(display_short)|uniprotkb:CG7736(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109533|imex:IM-9552-474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523926.1|flybase:FBgn0035540|ensemblmetazoa:FBgn0035540(gene)|ensemblmetazoa:FBtr0073293(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR010989(t-SNARE)|interpro:IPR028676 flybase:FBgn0037084|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2017/03/30 rogid:AVwCimBFmfW0aitbEjEpGIjqZWA7227 rogid:hsRWyXsxYy8tLrP1Rl+lnuYDBH07227 intact-crc:707F21A595DCE224|rigid:F20NsIAJqewXja+ydXjxWKZ1ZEw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JZN0 uniprotkb:Q9U1L3 intact:EBI-92490|intact:EBI-2109559|ensemblmetazoa:FBpp0086627 intact:EBI-2109555 psi-mi:q7jzn0_drome(display_long)|uniprotkb:Sec61beta(gene name)|psi-mi:Sec61beta(display_short)|uniprotkb:sec61beta(gene name synonym)|uniprotkb:Sec61-beta(gene name synonym)|uniprotkb:Sec61beta-RA(gene name synonym)|uniprotkb:Dmel_CG10130(orf name)|uniprotkb:CG10130(orf name)|uniprotkb:DSec61beta(gene name synonym)|uniprotkb:Dmel\CG10130(gene name synonym)|uniprotkb:Sec1(gene name synonym)|uniprotkb:Sec61(gene name synonym)|uniprotkb:Secbeta61(gene name synonym)|uniprotkb:dSec61beta(gene name synonym)|uniprotkb:"l(2)07214"(gene name synonym)|uniprotkb:sec61b(gene name synonym) psi-mi:q9u1l3_drome(display_long)|uniprotkb:"EG:BACR7A4.5"(gene name synonym)|uniprotkb:CG11642(orf name)|uniprotkb:TRAM(gene name)|psi-mi:TRAM(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109552|imex:IM-9552-476 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652037.1|flybase:FBgn0010638|ensemblmetazoa:FBgn0010638(gene)|ensemblmetazoa:FBtr0087498(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|reactome:R-DME-9609523 flybase:FBgn0040340|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016447(Translocation associated membrane protein) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:RzxFF9bAFufAgJ6A8aA7ZD7BVd87227 rogid:epGYqkmeES/ubQXA+FJsweSYEsA7227 intact-crc:571B5D6985E40881|rigid:6vs8Etd0d1m1lXrB2H7OnUuHaz8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SXG7 uniprotkb:P12982 intact:EBI-118303|uniprotkb:Q9VQZ9|ensemblmetazoa:FBpp0077144 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 psi-mi:q8sxg7_drome(display_long)|uniprotkb:Secp43(gene name)|psi-mi:Secp43(display_short)|uniprotkb:Dmel\CG15440(gene name synonym)|uniprotkb:cg15440(gene name synonym)|uniprotkb:tRNA selenocysteine-associated protein 1(gene name synonym)|uniprotkb:CG15440(orf name)|uniprotkb:Dmel_CG15440(orf name) psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109566|imex:IM-9552-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608837.2|flybase:FBgn0031607|ensemblmetazoa:FBgn0031607(gene)|ensemblmetazoa:FBtr0077454(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034510|interpro:IPR035979|interpro:IPR041085 refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WBXfxCWvCmLGxGUyM1ldkyZhvug7227 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 intact-crc:80FE08D113CC8EF4|rigid:Bt2CrNP6vpkb+d4pn/HCxnhpVE4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNH5 uniprotkb:Q9W2M2 intact:EBI-93503|ensemblmetazoa:FBpp0078327 intact:EBI-261090|uniprotkb:Q0E903|uniprotkb:Q0E904|uniprotkb:Q7YWL2|uniprotkb:Q961P0|uniprotkb:Q9W2M1|uniprotkb:Q9W2M3|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 psi-mi:q9vnh5_drome(display_long)|uniprotkb:Dmel\CG2091(gene name)|psi-mi:Dmel\CG2091(display_short)|uniprotkb:Dmel_CG2091(orf name)|uniprotkb:CG2091(orf name) psi-mi:trea_drome(display_long)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:CG9364(orf name)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109571|imex:IM-9552-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649582.1|flybase:FBgn0037372|ensemblmetazoa:FBgn0037372(gene)|ensemblmetazoa:FBtr0078678(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR036265|reactome:R-DME-429958 refseq:NP_524821.1|refseq:NP_726023.1|refseq:NP_726024.1|refseq:NP_726025.1|refseq:NP_726026.1|refseq:NP_726027.1|flybase:FBgn0003748|refseq:NP_001261115.1|dip:DIP-23202N|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript)|go:"GO:0004555"(alpha,alpha-trehalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005991"(trehalose metabolic process)|go:"GO:0005993"(trehalose catabolic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR001661(Glycoside hydrolase, family 37)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR018232 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UApCNJSoLyVYlXePDLUm/MKUT7c7227 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 intact-crc:1F15C13E4C5A8636|rigid:vmzSpO+jnL+rnrI9acdn84GgLWo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VT75 uniprotkb:P22769 intact:EBI-133584|ensemblmetazoa:FBpp0076077|ensemblmetazoa:FBpp0076078|ensemblmetazoa:FBpp0076079|ensemblmetazoa:FBpp0076080|ensemblmetazoa:FBpp0076081 intact:EBI-93148|uniprotkb:Q9VXI9|ensemblmetazoa:FBpp0073989 psi-mi:q9vt75_drome(display_long)|uniprotkb:vnc(gene name)|psi-mi:vnc(display_short)|uniprotkb:Ard1(gene name synonym)|uniprotkb:ARD1(gene name synonym)|uniprotkb:DmAAF50178(gene name synonym)|uniprotkb:Dmel\CG11989(gene name synonym)|uniprotkb:NAA10(gene name synonym)|uniprotkb:Naa10(gene name synonym)|uniprotkb:ard1(gene name synonym)|uniprotkb:dArd1(gene name synonym)|uniprotkb:"l(3)67BDk"(gene name synonym)|uniprotkb:Dmel_CG11989(orf name)|uniprotkb:11(gene name synonym)|uniprotkb:dNaa10(gene name synonym)|uniprotkb:CG11989(orf name) psi-mi:psa71_drome(display_long)|uniprotkb:Prosalpha4(gene name)|psi-mi:Prosalpha4(display_short)|uniprotkb:PROS-28.1(gene name synonym)|uniprotkb:PROS-Dm28.1(gene name synonym)|uniprotkb:Pros28.1(gene name synonym)|uniprotkb:Proteasome 28 kDa subunit 1(gene name synonym)|uniprotkb:CG3422(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109581|imex:IM-9552-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648378.1|refseq:NP_729581.1|refseq:NP_729582.1|refseq:NP_729583.1|refseq:NP_729584.1|flybase:FBgn0263251|ensemblmetazoa:FBgn0263251(gene)|ensemblmetazoa:FBtr0076348(transcript)|ensemblmetazoa:FBtr0076349(transcript)|ensemblmetazoa:FBtr0076350(transcript)|ensemblmetazoa:FBtr0076351(transcript)|ensemblmetazoa:FBtr0076352(transcript)|go:"GO:0016573"(histone acetylation)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031248"(protein acetyltransferase complex)|go:"GO:0031415"(NatA complex)|go:"GO:0048477"(oogenesis)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase) refseq:NP_525092.1|flybase:FBgn0004066|ensemblmetazoa:FBgn0004066(gene)|ensemblmetazoa:FBtr0074210(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-69601|reactome:R-DME-69017|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-450408|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-4608870|reactome:R-DME-432395|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|dip:DIP-17376N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o3xmQfTimj+I6AK4peQ6/M6eaXU7227 rogid:gQpRF01CDAsvV4Rc2YSFf8drjtY7227 intact-crc:6686C982B3A7DF65|rigid:p+21uwz3QlP4zdfkpe64sI9ibtk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:E4NKJ7 uniprotkb:Q9VU68 intact:EBI-2109097|ensemblmetazoa:FBpp0071844 intact:EBI-135985|ensemblmetazoa:FBpp0075581|uniprotkb:Q8IQJ6 psi-mi:e4nkj7_drome(display_long)|uniprotkb:CG2852-RA(gene name)|psi-mi:CG2852-RA(display_short) psi-mi:wdr1_drome(display_long)|uniprotkb:CG10724(orf name)|uniprotkb:flr(gene name)|psi-mi:flr(display_short)|uniprotkb:Protein flare(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109576|imex:IM-9552-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|ensemblmetazoa:FBgn0034753(gene)|ensemblmetazoa:FBtr0071933(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity) refseq:NP_648642.1|refseq:NP_729891.1|flybase:FBgn0260049|ensemblmetazoa:FBgn0260049(gene)|ensemblmetazoa:FBtr0075845(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0040011"(locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-DME-114608|dip:DIP-18795N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:3aIBAqr3Fyg0C5AlSkwGpkjAE4c7227 rogid:hpellsoqmr8WNuG+YWDVM/LIQ9Q7227 intact-crc:482C75FA8EC38ECA|rigid:oiLVISEd+ssGZjM1/TgYdMBN4B0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q27331 uniprotkb:A1Z9E3 intact:EBI-103678|uniprotkb:Q8SXT2|uniprotkb:Q9VK48|ensemblmetazoa:FBpp0079999|ensemblmetazoa:FBpp0080000|ensemblmetazoa:FBpp0080001|ensemblmetazoa:FBpp0294002|ensemblmetazoa:FBpp0307596|ensemblmetazoa:FBpp0307597 intact:EBI-133675|intact:EBI-2109586|ensemblmetazoa:FBpp0086790|ensemblmetazoa:FBpp0290603 psi-mi:vata2_drome(display_long)|uniprotkb:Vha68-2(gene name)|psi-mi:Vha68-2(display_short)|uniprotkb:VHAA2(gene name synonym)|uniprotkb:CG3762(orf name)|uniprotkb:Vacuolar proton pump subunit alpha 2(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit 2(gene name synonym) psi-mi:a1z9e3_drome(display_long)|uniprotkb:mEFTu1(gene name)|psi-mi:mEFTu1(display_short)|uniprotkb:EfTuM(gene name synonym)|uniprotkb:Dmel\CG6050(gene name synonym)|uniprotkb:EF-Tu1(gene name synonym)|uniprotkb:efTuM(gene name synonym)|uniprotkb:eftu-M(gene name synonym)|uniprotkb:"l(3)L4569"(gene name synonym)|uniprotkb:mtEF-Tu(gene name synonym)|uniprotkb:CG6050(orf name)|uniprotkb:Dmel_CG6050(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109591|imex:IM-9552-478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001260424.1|refseq:NP_001260425.1|refseq:NP_652004.2|refseq:NP_723775.1|refseq:NP_723776.1|ensemblmetazoa:FBgn0263598(gene)|ensemblmetazoa:FBtr0080418(transcript)|ensemblmetazoa:FBtr0080419(transcript)|ensemblmetazoa:FBtr0080420(transcript)|ensemblmetazoa:FBtr0305551(transcript)|ensemblmetazoa:FBtr0336613(transcript)|ensemblmetazoa:FBtr0336614(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0016197"(endosomal transport)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|flybase:FBgn0263598|refseq:NP_001246015.1 refseq:NP_001163144.1|refseq:NP_524752.1|flybase:FBgn0024556|ensemblmetazoa:FBgn0024556(gene)|ensemblmetazoa:FBtr0087670(transcript)|ensemblmetazoa:FBtr0301389(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:O722SCX9A2L6VQXSPu5VjCJJrOA7227 rogid:+Cf2LceMe6TUIxKcs4ZOAPsyycQ7227 intact-crc:746A34AE798BB131|rigid:Mgx2nCR6oVGNCW2SgDBnmXYdfb8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V6B9 uniprotkb:Q7KKI9 intact:EBI-179307|ensemblmetazoa:FBpp0087063 intact:EBI-2109596|ensemblmetazoa:FBpp0080013 psi-mi:nup54_drome(display_long)|uniprotkb:CG8831(orf name)|uniprotkb:Nup54(gene name)|psi-mi:Nup54(display_short) psi-mi:q7kki9_drome(display_long)|uniprotkb:Pk34A(gene name)|psi-mi:Pk34A(display_short)|uniprotkb:CG5182(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109600|imex:IM-9552-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610783.1|flybase:FBgn0033737|dip:DIP-19285N|ensemblmetazoa:FBgn0033737(gene)|ensemblmetazoa:FBtr0087952(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q9V6B9|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749 flybase:FBgn0028410|ensemblmetazoa:FBgn0028410(gene)|ensemblmetazoa:FBtr0080432(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0RSPWkJnRddLDMAOCRvpHWcUlSo7227 rogid:vHS7jWE9k2Z/WZU3fKejxK5ISVc7227 intact-crc:C15569D71DD47579|rigid:Nqecs3tiVuMktSLaO4mooIUcXIA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48462 uniprotkb:P06754 intact:EBI-869621|uniprotkb:Q9W2V5|ensemblmetazoa:FBpp0071382|ensemblmetazoa:FBpp0305497 intact:EBI-176070|uniprotkb:P09492|uniprotkb:Q7KSH8|uniprotkb:Q7KSI1|uniprotkb:Q95SZ3|uniprotkb:Q9VF96|uniprotkb:Q9VF97|uniprotkb:A4V2Y4 psi-mi:pp1b_drome(display_long)|uniprotkb:Protein flap wing(gene name synonym)|uniprotkb:flw(gene name)|psi-mi:flw(display_short)|uniprotkb:PP1-9C(gene name synonym)|uniprotkb:PP1-BETA-9C(gene name synonym)|uniprotkb:CG2096(orf name) psi-mi:tpm1_drome(display_long)|uniprotkb:Tm1(gene name)|psi-mi:Tm1(display_short)|uniprotkb:TmII(gene name synonym)|uniprotkb:Tropomyosin II(gene name synonym)|uniprotkb:Cytoskeletal tropomyosin(gene name synonym)|uniprotkb:CG4898(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109605|imex:IM-9552-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524738.1|flybase:FBgn0000711|refseq:NP_001259407.1|ensemblmetazoa:FBgn0000711(gene)|ensemblmetazoa:FBtr0071447(transcript)|ensemblmetazoa:FBtr0333305(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1905330"(regulation of morphogenesis of an epithelium)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|reactome:R-DME-2565942|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|reactome:R-DME-5625740|reactome:R-DME-5627123 refseq:NP_732001.3|refseq:NP_524360.2|refseq:NP_732002.1|refseq:NP_732003.1|refseq:NP_732004.1|refseq:NP_996216.1|flybase:FBgn0003721|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070865"(investment cone)|interpro:IPR000533(Tropomyosin) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PZSfwmpwqFs81zLVfparcg1xIZY7227 rogid:SOkGswbfk//tyBQ+1B/I1VL7PV47227 intact-crc:3A22F1D026D7DF46|rigid:ynJjsOUV8c9PZJ/thSss5YcOP8o false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P15007 uniprotkb:P25007 intact:EBI-111852|uniprotkb:A4UZY9|uniprotkb:A5XD39|uniprotkb:A5XD43|uniprotkb:Q8IPX8|uniprotkb:Q8MT10|uniprotkb:Q9VQ38|uniprotkb:B9EQS7|uniprotkb:C0PV73|ensemblmetazoa:FBpp0077571|ensemblmetazoa:FBpp0077572|ensemblmetazoa:FBpp0077573|ensemblmetazoa:FBpp0077574 intact:EBI-178070|uniprotkb:Q9VXH8|ensemblmetazoa:FBpp0074017 psi-mi:eno_drome(display_long)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Eno(gene name)|psi-mi:Eno(display_short)|uniprotkb:CG17654(orf name) psi-mi:ppia_drome(display_long)|uniprotkb:Cyp1(gene name)|psi-mi:Cyp1(display_short)|uniprotkb:Cyp-1(gene name synonym)|uniprotkb:CG9916(orf name)|uniprotkb:Cyclophilin(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109619|imex:IM-9552-480 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162853.1|refseq:NP_477421.1|refseq:NP_722721.1|refseq:NP_722722.1|refseq:NP_722723.1|refseq:NP_722724.1|flybase:FBgn0000579|ensemblmetazoa:FBgn0000579(gene)|ensemblmetazoa:FBtr0077905(transcript)|ensemblmetazoa:FBtr0077906(transcript)|ensemblmetazoa:FBtr0077907(transcript)|ensemblmetazoa:FBtr0077908(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0061621"(canonical glycolysis)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:5WRO|reactome:R-DME-70171|reactome:R-DME-70263 refseq:NP_523366.2|flybase:FBgn0004432|dip:DIP-18774N|ensemblmetazoa:FBgn0004432(gene)|ensemblmetazoa:FBtr0074238(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:BbDu+UNk1ycxJO2gZt7R2JaBM2s7227 rogid:gnOfxMK/CrIiMAiTXvzdnaCMJZA7227 intact-crc:A605F9F7FFC55B67|rigid:/Xs4ns7r4qQL2a+Rs6WUl9+FRec false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P15007 uniprotkb:Q8MR61 intact:EBI-111852|uniprotkb:A4UZY9|uniprotkb:A5XD39|uniprotkb:A5XD43|uniprotkb:Q8IPX8|uniprotkb:Q8MT10|uniprotkb:Q9VQ38|uniprotkb:B9EQS7|uniprotkb:C0PV73|ensemblmetazoa:FBpp0077571|ensemblmetazoa:FBpp0077572|ensemblmetazoa:FBpp0077573|ensemblmetazoa:FBpp0077574 intact:EBI-2109613|ensemblmetazoa:FBpp0072484 psi-mi:eno_drome(display_long)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Eno(gene name)|psi-mi:Eno(display_short)|uniprotkb:CG17654(orf name) psi-mi:q8mr61_drome(display_long)|uniprotkb:Dci(gene name)|psi-mi:Dci(display_short)|uniprotkb:CG13890(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109610|imex:IM-9552-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162853.1|refseq:NP_477421.1|refseq:NP_722721.1|refseq:NP_722722.1|refseq:NP_722723.1|refseq:NP_722724.1|flybase:FBgn0000579|ensemblmetazoa:FBgn0000579(gene)|ensemblmetazoa:FBtr0077905(transcript)|ensemblmetazoa:FBtr0077906(transcript)|ensemblmetazoa:FBtr0077907(transcript)|ensemblmetazoa:FBtr0077908(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0061621"(canonical glycolysis)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:5WRO|reactome:R-DME-70171|reactome:R-DME-70263 flybase:FBgn0035169|ensemblmetazoa:FBgn0035169(gene)|ensemblmetazoa:FBtr0072587(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005777"(peroxisome)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR029045 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:BbDu+UNk1ycxJO2gZt7R2JaBM2s7227 rogid:BRLSQdMlOcXIGdtDztkxKvPpRyo7227 intact-crc:EB06101E76F619B9|rigid:u1w+Sy4dfNjGyKnosjzTswD9vdc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P91938 uniprotkb:P15007 intact:EBI-208742|uniprotkb:Q961E3|uniprotkb:Q9W3H2|uniprotkb:Q9W3H3|uniprotkb:Q1RKZ0|uniprotkb:Q53YG2|ensemblmetazoa:FBpp0071116 intact:EBI-111852|uniprotkb:A4UZY9|uniprotkb:A5XD39|uniprotkb:A5XD43|uniprotkb:Q8IPX8|uniprotkb:Q8MT10|uniprotkb:Q9VQ38|uniprotkb:B9EQS7|uniprotkb:C0PV73|ensemblmetazoa:FBpp0077571|ensemblmetazoa:FBpp0077572|ensemblmetazoa:FBpp0077573|ensemblmetazoa:FBpp0077574 psi-mi:trxr1_drome(display_long)|uniprotkb:Trxr-1(gene name)|psi-mi:Trxr-1(display_short)|uniprotkb:GR(gene name synonym)|uniprotkb:CG2151(orf name) psi-mi:eno_drome(display_long)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Eno(gene name)|psi-mi:Eno(display_short)|uniprotkb:CG17654(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109624|imex:IM-9552-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511082.2|refseq:NP_727251.1|refseq:NP_727252.1|flybase:FBgn0020653|dip:DIP-19145N|ensemblmetazoa:FBgn0020653(gene)|ensemblmetazoa:FBtr0071168(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016209"(antioxidant activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:2NVK|rcsb pdb:3DGH|rcsb pdb:3DH9|reactome:R-DME-3299685|reactome:R-DME-499943|reactome:R-DME-5263617|reactome:R-DME-5628897 refseq:NP_001162853.1|refseq:NP_477421.1|refseq:NP_722721.1|refseq:NP_722722.1|refseq:NP_722723.1|refseq:NP_722724.1|flybase:FBgn0000579|ensemblmetazoa:FBgn0000579(gene)|ensemblmetazoa:FBtr0077905(transcript)|ensemblmetazoa:FBtr0077906(transcript)|ensemblmetazoa:FBtr0077907(transcript)|ensemblmetazoa:FBtr0077908(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0061621"(canonical glycolysis)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:5WRO|reactome:R-DME-70171|reactome:R-DME-70263 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9UYtoqz7kwWtFnWOX8rmwyYlY9M7227 rogid:BbDu+UNk1ycxJO2gZt7R2JaBM2s7227 intact-crc:D0EF4E2B3D6CB5B6|rigid:ANe0SSS0RX+axYMGKd0mX0vvHdw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q5BIK1 uniprotkb:Q9I7X6 intact:EBI-2109647|ensemblmetazoa:FBpp0077637 intact:EBI-216406|uniprotkb:Q9W540|uniprotkb:Q7KW04|uniprotkb:O46078|intact:EBI-216413|ensemblmetazoa:FBpp0070306 psi-mi:q5bik1_drome(display_long)|uniprotkb:CG5001(orf name) psi-mi:carme_drome(display_long)|uniprotkb:CG11596(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109644|imex:IM-9552-482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0031322|ensemblmetazoa:FBgn0031322(gene)|ensemblmetazoa:FBtr0077972(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding) refseq:NP_569963.1|refseq:NP_726779.1|refseq:NP_726780.1|flybase:FBgn0023522|refseq:NP_001259154.1|refseq:NP_001259155.1|ensemblmetazoa:FBgn0023522(gene)|ensemblmetazoa:FBtr0070319(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0030735"(carnosine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0035498"(carnosine metabolic process)|interpro:IPR012901(N2227-like)|interpro:IPR029063|reactome:R-DME-70921 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:3vph+GcjGAmq1NMijC/R9MclTgQ7227 rogid:GUnznZeecSwEkg/MC0QDM+N9cP47227 intact-crc:0496C0DA703CF9EF|rigid:6zkk4UvBVFTzhPJPzmRFljxFDKs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:E4NKJ7 uniprotkb:P15007 intact:EBI-2109097|ensemblmetazoa:FBpp0071844 intact:EBI-111852|uniprotkb:A4UZY9|uniprotkb:A5XD39|uniprotkb:A5XD43|uniprotkb:Q8IPX8|uniprotkb:Q8MT10|uniprotkb:Q9VQ38|uniprotkb:B9EQS7|uniprotkb:C0PV73|ensemblmetazoa:FBpp0077571|ensemblmetazoa:FBpp0077572|ensemblmetazoa:FBpp0077573|ensemblmetazoa:FBpp0077574 psi-mi:e4nkj7_drome(display_long)|uniprotkb:CG2852-RA(gene name)|psi-mi:CG2852-RA(display_short) psi-mi:eno_drome(display_long)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Eno(gene name)|psi-mi:Eno(display_short)|uniprotkb:CG17654(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109639|imex:IM-9552-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|ensemblmetazoa:FBgn0034753(gene)|ensemblmetazoa:FBtr0071933(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity) refseq:NP_001162853.1|refseq:NP_477421.1|refseq:NP_722721.1|refseq:NP_722722.1|refseq:NP_722723.1|refseq:NP_722724.1|flybase:FBgn0000579|ensemblmetazoa:FBgn0000579(gene)|ensemblmetazoa:FBtr0077905(transcript)|ensemblmetazoa:FBtr0077906(transcript)|ensemblmetazoa:FBtr0077907(transcript)|ensemblmetazoa:FBtr0077908(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0061621"(canonical glycolysis)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:5WRO|reactome:R-DME-70171|reactome:R-DME-70263 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:3aIBAqr3Fyg0C5AlSkwGpkjAE4c7227 rogid:BbDu+UNk1ycxJO2gZt7R2JaBM2s7227 intact-crc:49CE59EDD51A0F8A|rigid:pbxIRkjdQ7zsOYX8Ke7cCC64ApE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P15007 uniprotkb:Q9VSW1 intact:EBI-111852|uniprotkb:A4UZY9|uniprotkb:A5XD39|uniprotkb:A5XD43|uniprotkb:Q8IPX8|uniprotkb:Q8MT10|uniprotkb:Q9VQ38|uniprotkb:B9EQS7|uniprotkb:C0PV73|ensemblmetazoa:FBpp0077571|ensemblmetazoa:FBpp0077572|ensemblmetazoa:FBpp0077573|ensemblmetazoa:FBpp0077574 intact:EBI-2109632|uniprotkb:Q8T0B8|ensemblmetazoa:FBpp0099884 psi-mi:eno_drome(display_long)|uniprotkb:2-phosphoglycerate dehydratase(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Eno(gene name)|psi-mi:Eno(display_short)|uniprotkb:CG17654(orf name) psi-mi:q9vsw1_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109629|imex:IM-9552-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162853.1|refseq:NP_477421.1|refseq:NP_722721.1|refseq:NP_722722.1|refseq:NP_722723.1|refseq:NP_722724.1|flybase:FBgn0000579|ensemblmetazoa:FBgn0000579(gene)|ensemblmetazoa:FBtr0077905(transcript)|ensemblmetazoa:FBtr0077906(transcript)|ensemblmetazoa:FBtr0077907(transcript)|ensemblmetazoa:FBtr0077908(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0061621"(canonical glycolysis)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:5WRO|reactome:R-DME-70171|reactome:R-DME-70263 refseq:NP_648300.3|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0076501(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044|reactome:R-DME-173599|reactome:R-DME-3322077 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:BbDu+UNk1ycxJO2gZt7R2JaBM2s7227 rogid:oF/cK+tup8s3UfAZsGKX9Xka2Xc7227 intact-crc:E3D887AEA0E345EC|rigid:pofkov2Jc7bWVUidyqwV2VNPCjs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q960X4 uniprotkb:Q9VGH5 intact:EBI-124365|uniprotkb:O97425|ensemblmetazoa:FBpp0305388|ensemblmetazoa:FBpp0070636 intact:EBI-132496|ensemblmetazoa:FBpp0088856|ensemblmetazoa:FBpp0088858 psi-mi:tip60_drome(display_long)|uniprotkb:Tip60(gene name)|psi-mi:Tip60(display_short)|uniprotkb:CG6121(orf name) psi-mi:q9vgh5_drome(display_long)|uniprotkb:110(gene name synonym)|uniprotkb:46(gene name synonym)|uniprotkb:Dmel\CG6946(gene name synonym)|uniprotkb:Glo(gene name synonym)|uniprotkb:anon-WO0118547.328(gene name synonym)|uniprotkb:"l(3)S011046"(gene name synonym)|uniprotkb:"l(3)S11046"(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:p67-K(gene name synonym)|uniprotkb:Dmel_CG6946(orf name)|uniprotkb:glo(gene name)|psi-mi:glo(display_short)|uniprotkb:cg6946(gene name synonym)|uniprotkb:CG6946(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109653|imex:IM-9552-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572151.1|flybase:FBgn0026080|refseq:NP_001259234.1|ensemblmetazoa:FBtr0070668(transcript)|ensemblmetazoa:FBtr0333186(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:1990188"(euchromatin binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|reactome:R-DME-2559586|reactome:R-DME-5693548|reactome:R-DME-5693565|reactome:R-DME-9018519|ensemblmetazoa:FBgn0026080(gene) refseq:NP_650120.1|refseq:NP_731639.1|flybase:FBgn0259139|ensemblmetazoa:FBgn0259139(gene)|ensemblmetazoa:FBtr0089917(transcript)|ensemblmetazoa:FBtr0089919(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007311"(maternal specification of dorsal/ventral axis, oocyte, germ-line encoded)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0051276"(chromosome organization)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:5UZG|rcsb pdb:5UZM|rcsb pdb:5UZN|reactome:R-DME-6803529|reactome:R-DME-72163|go:"GO:0003723"(RNA binding) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YZeS6GSo2rydZfUJDo1L43+TPX07227 rogid:gkWThCb3EPh7mJrkyQBlt6iShwo7227 intact-crc:0941E5F39D3A5A8B|rigid:wNgYpATWMD7WeV5nKGdsj+D/tHA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P41900 uniprotkb:Q9I7X6 intact:EBI-2109663|uniprotkb:Q9VGX4|ensemblmetazoa:FBpp0081786 intact:EBI-216406|uniprotkb:Q9W540|uniprotkb:Q7KW04|uniprotkb:O46078|intact:EBI-216413|ensemblmetazoa:FBpp0070306 psi-mi:t2fb_drome(display_long)|uniprotkb:TfIIFbeta(gene name)|psi-mi:TfIIFbeta(display_short)|uniprotkb:TFIIF30(gene name synonym)|uniprotkb:Transcription initiation factor IIF subunit beta(gene name synonym)|uniprotkb:ATP-dependent helicase TfIIF-beta(gene name synonym)|uniprotkb:CG6538(orf name) psi-mi:carme_drome(display_long)|uniprotkb:CG11596(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109667|imex:IM-9552-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524305.2|flybase:FBgn0010421|ensemblmetazoa:FBgn0010421(gene)|ensemblmetazoa:FBtr0082310(transcript)|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003196(Transcription initiation factor IIF, beta subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040450|interpro:IPR040504|reactome:R-DME-112382|reactome:R-DME-113418|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-6803529|reactome:R-DME-6807505|reactome:R-DME-72086|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72203|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-75955|reactome:R-DME-76042|reactome:R-DME-77075|reactome:R-DME-9018519 refseq:NP_569963.1|refseq:NP_726779.1|refseq:NP_726780.1|flybase:FBgn0023522|refseq:NP_001259154.1|refseq:NP_001259155.1|ensemblmetazoa:FBgn0023522(gene)|ensemblmetazoa:FBtr0070319(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0030735"(carnosine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0035498"(carnosine metabolic process)|interpro:IPR012901(N2227-like)|interpro:IPR029063|reactome:R-DME-70921 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:R0i7x0onboJkpzihJh2eSz2Qvcg7227 rogid:GUnznZeecSwEkg/MC0QDM+N9cP47227 intact-crc:7FF459A0AA123E2A|rigid:NdUZDxHV+sytyTkhJKrCgbHARmU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q08605 uniprotkb:Q86B87 intact:EBI-300317|uniprotkb:Q08083|uniprotkb:Q7JN57|uniprotkb:Q8MYL3|uniprotkb:Q8T387|uniprotkb:Q9V3X7|uniprotkb:Q9VUH2|uniprotkb:O18349|uniprotkb:O18350|uniprotkb:O18526 intact:EBI-124784|uniprotkb:A1A725|uniprotkb:A8JR64|uniprotkb:A8JR66|ensemblmetazoa:FBpp0083478|uniprotkb:P91932|uniprotkb:Q24099|uniprotkb:Q24100|uniprotkb:Q24101|uniprotkb:Q24482|uniprotkb:Q24483|uniprotkb:Q86B84|uniprotkb:Q86B85|uniprotkb:Q86B86|uniprotkb:Q8IN28|uniprotkb:Q8IN29|uniprotkb:Q8IN30|uniprotkb:Q8IN31|uniprotkb:Q8IN32|uniprotkb:Q8IN33|uniprotkb:Q8IN34|uniprotkb:Q8WTI9|uniprotkb:Q8WTJ0|uniprotkb:Q8WTJ1|uniprotkb:Q95R78|uniprotkb:Q95ZF4|uniprotkb:Q95ZF5|uniprotkb:Q95ZF6|uniprotkb:Q95ZF7|uniprotkb:Q95ZF8|uniprotkb:Q9N6U6|uniprotkb:Q9N6U7|uniprotkb:Q9N6U8|uniprotkb:Q9N6U9|uniprotkb:Q9N6V0|uniprotkb:Q9N6V1|uniprotkb:Q9N6V2|uniprotkb:Q9N6V3|uniprotkb:Q9N6V4|uniprotkb:Q9N6V5|uniprotkb:Q9N6V6|uniprotkb:Q9N6V7|uniprotkb:Q9N6V8|uniprotkb:Q9N6V9|uniprotkb:Q9N6W0|uniprotkb:Q9N6W1|uniprotkb:Q9N6W2|uniprotkb:Q9N6W3|uniprotkb:Q9N6W4|uniprotkb:Q9N6W5|uniprotkb:Q9VDA9|uniprotkb:Q9VDB2|uniprotkb:Q9VDB3|uniprotkb:Q9VDB4|uniprotkb:Q9VDB5 psi-mi:gaga_drome(display_long)|uniprotkb:Trl(gene name)|psi-mi:Trl(display_short)|uniprotkb:GAGA(gene name synonym)|uniprotkb:TFGAGA(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:GAGA factor(gene name synonym)|uniprotkb:Adh transcription factor 2(gene name synonym)|uniprotkb:Neural conserved at 70F(gene name synonym)|uniprotkb:Adf-2(gene name synonym)|uniprotkb:Nc70F(gene name synonym)|uniprotkb:CG33261(orf name) psi-mi:mmd4_drome(display_long)|uniprotkb:"mod(mdg4)"(gene name)|psi-mi:"mod(mdg4)"(display_short)|uniprotkb:bpd(gene name synonym)|uniprotkb:doom(gene name synonym)|uniprotkb:"E(var)3-93D"(gene name synonym)|uniprotkb:CG32491(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109658|imex:IM-9552-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000280"(nuclear division)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007549"(dosage compensation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0034728"(nucleosome organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:1901409"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990000"(amyloid fibril formation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR015318(Zinc finger, GAGAG binding factor)|rcsb pdb:1YUI|rcsb pdb:1YUJ|go:"GO:0035075"(response to ecdysone)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|refseq:NP_001034014.1|refseq:NP_996077.1|refseq:NP_996078.1|refseq:NP_996079.1|refseq:NP_996080.1|refseq:NP_996081.1|refseq:NP_996082.1|flybase:FBgn0013263 ensemblmetazoa:FBgn0002781(gene)|ensemblmetazoa:FBtr0084079(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007141"(male meiosis I)|go:"GO:0008354"(germ cell migration)|refseq:NP_001097856.1|refseq:NP_001097857.1|refseq:NP_001097858.1|refseq:NP_524936.2|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0031208"(POZ domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|refseq:NP_732619.1|refseq:NP_732620.1|refseq:NP_732621.1|refseq:NP_732622.1|refseq:NP_732624.1|refseq:NP_732625.1|refseq:NP_732626.1|refseq:NP_732627.1|refseq:NP_732628.1|refseq:NP_732629.1|refseq:NP_732630.1|refseq:NP_732631.1|refseq:NP_732632.1|refseq:NP_732633.1|refseq:NP_732634.1|refseq:NP_732635.1|refseq:NP_732636.1|flybase:FBgn0002781|refseq:NP_732623.2|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007588(Zinc finger, FLYWCH-type)|interpro:IPR011333(BTB/POZ fold)|mint:Q86B87|refseq:NP_788698.1|refseq:NP_788699.1|refseq:NP_788700.1|refseq:NP_788701.1|refseq:NP_788702.1|refseq:NP_788703.1|refseq:NP_788704.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:s2lpiYJCLr9x3aKiQRvlG3gE9nk7227 rogid:b2OX/raroy6BMkaSC4EuYYprayM7227 intact-crc:D43BC6E626CFA980|rigid:0h2fuIuDflGaMA8r38cgOMueDBY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48555 uniprotkb:Q6NR18 intact:EBI-115197|uniprotkb:Q540X1|ensemblmetazoa:FBpp0070558|ensemblmetazoa:FBpp0070559|uniprotkb:Q9W4Q6 intact:EBI-2108814 psi-mi:rala_drome(display_long)|uniprotkb:Rala(gene name)|psi-mi:Rala(display_short)|uniprotkb:CG2849(orf name) psi-mi:q6nr18_drome(display_long)|uniprotkb:Pld(gene name)|psi-mi:Pld(display_short)|uniprotkb:CG12110(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109682|imex:IM-9552-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015286(gene)|ensemblmetazoa:FBtr0070583(transcript)|ensemblmetazoa:FBtr0070584(transcript)|go:"GO:0003924"(GTPase activity)|rcsb pdb:5CM9|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0019003"(GDP binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:5CM8|refseq:NP_525063.1|refseq:NP_726882.1|flybase:FBgn0015286|dip:DIP-19199N flybase:FBgn0286511|go:"GO:0004630"(phospholipase D activity)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007349"(cellularization)|go:"GO:0007602"(phototransduction)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048215"(positive regulation of Golgi vesicle fusion to target membrane)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR036871 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sTSyV5P4zR3/IGjwg6Ov0YFUl6g7227 rogid:o6ATxLbRQIQbVWqBeUlQCXkKktM7227 intact-crc:472ABE4CEAC7FB90|rigid:UEtERbstoFa6eR7fb+QzOU3II/c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VGK3 uniprotkb:E4NKJ7 intact:EBI-175886|ensemblmetazoa:FBpp0081899 intact:EBI-2109097|ensemblmetazoa:FBpp0071844 psi-mi:q9vgk3_drome(display_long)|uniprotkb:Dmel\CG14715(gene name)|psi-mi:Dmel\CG14715(display_short)|uniprotkb:"BcDNA:GM09283"(gene name synonym)|uniprotkb:"BcDNA:RH50927"(gene name synonym)|uniprotkb:FKBP13(gene name synonym)|uniprotkb:CG14715(orf name)|uniprotkb:Dmel_CG14715(orf name) psi-mi:e4nkj7_drome(display_long)|uniprotkb:CG2852-RA(gene name)|psi-mi:CG2852-RA(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109677|imex:IM-9552-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650101.1|flybase:FBgn0037930|ensemblmetazoa:FBgn0037930(gene)|ensemblmetazoa:FBtr0082423(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR044609 interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|ensemblmetazoa:FBgn0034753(gene)|ensemblmetazoa:FBtr0071933(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ipGuES5D0UTA4K1ZH8YFOBc18kw7227 rogid:3aIBAqr3Fyg0C5AlSkwGpkjAE4c7227 intact-crc:BA04CD3221AE2EEE|rigid:8LLtXWTSZiS69PZOVfcBV/TMDR4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z6R7 uniprotkb:P48555 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 intact:EBI-115197|uniprotkb:Q540X1|ensemblmetazoa:FBpp0070558|ensemblmetazoa:FBpp0070559|uniprotkb:Q9W4Q6 psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:rala_drome(display_long)|uniprotkb:Rala(gene name)|psi-mi:Rala(display_short)|uniprotkb:CG2849(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109691|imex:IM-9552-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 ensemblmetazoa:FBgn0015286(gene)|ensemblmetazoa:FBtr0070583(transcript)|ensemblmetazoa:FBtr0070584(transcript)|go:"GO:0003924"(GTPase activity)|rcsb pdb:5CM9|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0019003"(GDP binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:5CM8|refseq:NP_525063.1|refseq:NP_726882.1|flybase:FBgn0015286|dip:DIP-19199N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 rogid:sTSyV5P4zR3/IGjwg6Ov0YFUl6g7227 intact-crc:5F88E24446FE1407|rigid:BL8yoK6bsg5gyg1NrS5ecl/4N0s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48610 uniprotkb:P36188 intact:EBI-164883|uniprotkb:Q8IQB9|uniprotkb:Q8IQC0|uniprotkb:Q8T0S2|uniprotkb:Q9VST5|uniprotkb:Q9VST6|ensemblmetazoa:FBpp0076272|ensemblmetazoa:FBpp0303940|ensemblmetazoa:FBpp0311280 intact:EBI-251833|uniprotkb:Q0KHR0|uniprotkb:Q9VWY1|uniprotkb:Q9VWY2|uniprotkb:Q9VWY3|uniprotkb:Q9VWY4|ensemblmetazoa:FBpp0074298 psi-mi:karg_drome(display_long)|uniprotkb:Argk(gene name)|psi-mi:Argk(display_short)|uniprotkb:CG32031(orf name) psi-mi:tnni_drome(display_long)|uniprotkb:wupA(gene name)|psi-mi:wupA(display_short)|uniprotkb:HDP(gene name synonym)|uniprotkb:TnI(gene name synonym)|uniprotkb:CG7178(orf name)|uniprotkb:Protein wings apart-A(gene name synonym)|uniprotkb:Protein heldup(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109672|imex:IM-9552-484 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097556.2|refseq:NP_523988.2|refseq:NP_729446.1|refseq:NP_729447.1|refseq:NP_729448.1|flybase:FBgn0000116|refseq:NP_001286989.1|ensemblmetazoa:FBgn0000116(gene)|ensemblmetazoa:FBtr0076545(transcript)|ensemblmetazoa:FBtr0331550(transcript)|go:"GO:0004054"(arginine kinase activity)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|ensemblmetazoa:FBtr0345030(transcript) refseq:NP_523398.1|refseq:NP_728137.1|refseq:NP_728138.1|refseq:NP_728139.1|refseq:NP_728140.1|refseq:NP_728141.1|refseq:NP_728142.1|flybase:FBgn0283471|dip:DIP-22750N|ensemblmetazoa:FBgn0283471(gene)|ensemblmetazoa:FBtr0074524(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003779"(actin binding)|go:"GO:0005861"(troponin complex)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0030239"(myofibril assembly)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060047"(heart contraction)|interpro:IPR001978(Troponin)|interpro:IPR038077|reactome:R-DME-5578775 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cWY5EduospuyVVWWiOx1PKEsA4w7227 rogid:Ewyc6AfWJ/D3fa3cyiavnZYDahg7227 intact-crc:B873B7083BF70189|rigid:qrrmpuJ2FHcnGQIaBpyZVUcTftQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XYN7 uniprotkb:O17311 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 intact:EBI-2108373 psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:o17311_drome(display_long)|uniprotkb:beta2_dm(gene name synonym)|uniprotkb:CG3329(orf name)|uniprotkb:Pros-beta-2(gene name synonym)|uniprotkb:Prosbeta2(gene name)|psi-mi:Prosbeta2(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109710|imex:IM-9552-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N flybase:FBgn0023174|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 rogid:kKcHoGOVnpj4GwJCUwhH8LJFS4U7227 intact-crc:8F64E01E67A53A58|rigid:jCgfeQUOyJbB2fAW8xIGypXxVnM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJJ0 uniprotkb:O17311 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 intact:EBI-2108373 psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:o17311_drome(display_long)|uniprotkb:beta2_dm(gene name synonym)|uniprotkb:CG3329(orf name)|uniprotkb:Pros-beta-2(gene name synonym)|uniprotkb:Prosbeta2(gene name)|psi-mi:Prosbeta2(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109705|imex:IM-9552-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 flybase:FBgn0023174|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 rogid:kKcHoGOVnpj4GwJCUwhH8LJFS4U7227 intact-crc:33926021F05C6A31|rigid:ocXbSUosENduwzpATuczlV2vkhA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTG0 uniprotkb:Q8IR93 intact:EBI-196087|uniprotkb:Q8SZT3|ensemblmetazoa:FBpp0290653|ensemblmetazoa:FBpp0304951 intact:EBI-2109696|ensemblmetazoa:FBpp0073300 psi-mi:q9vtg0_drome(display_long)|uniprotkb:NaPi-III(gene name)|psi-mi:NaPi-III(display_short)|uniprotkb:CG7628-RA(gene name synonym)|uniprotkb:CR32078(gene name synonym)|uniprotkb:Dmel\CG42575(gene name synonym)|uniprotkb:Dromel_CG7628_FBtr0076213_mORF(gene name synonym)|uniprotkb:dPit(gene name synonym)|uniprotkb:Dmel_CG42575(orf name)|uniprotkb:CG42575(orf name)|uniprotkb:CG7628(orf name)|uniprotkb:dPiT(gene name synonym) psi-mi:q8ir93_drome(display_long)|uniprotkb:CG1938(orf name)|uniprotkb:Dlic(gene name)|psi-mi:Dlic(display_short)|uniprotkb:D-LIC(gene name synonym)|uniprotkb:DLIC(gene name synonym)|uniprotkb:DLIC2(gene name synonym)|uniprotkb:Dlic2(gene name synonym)|uniprotkb:Dmel\CG1938(gene name synonym)|uniprotkb:dlic(gene name synonym)|uniprotkb:dlic2(gene name synonym)|uniprotkb:"l(1)G0065"(gene name synonym)|uniprotkb:"l(1)G0190"(gene name synonym)|uniprotkb:Dmel_CG1938(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109700|imex:IM-9552-486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648441.1|flybase:FBgn0260795|refseq:NP_001261704.1|ensemblmetazoa:FBgn0260795(gene)|ensemblmetazoa:FBtr0301438(transcript)|ensemblmetazoa:FBtr0332705(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044341"(sodium-dependent phosphate transport)|interpro:IPR001204(Phosphate transporter)|reactome:R-DME-427652 refseq:NP_727503.1|flybase:FBgn0030276|ensemblmetazoa:FBgn0030276(gene)|ensemblmetazoa:FBtr0073444(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007409"(axonogenesis)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0030286"(dynein complex)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0043005"(neuron projection)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051028"(mRNA transport)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0pm8tDX+fi74FX9P0KEpd9xvtrQ7227 rogid:pMQwLoJS0UM2bxDx2Qno8b/6mIE7227 intact-crc:A204FB1129EBA93E|rigid:U7MBK/QV3DX+AoE+8hjaeewG0n0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTC4 uniprotkb:Q7K1Y4 intact:EBI-100085|ensemblmetazoa:FBpp0075999 intact:EBI-175932|intact:EBI-2108398|ensemblmetazoa:FBpp0086590 psi-mi:gall2_drome(display_long)|uniprotkb:galla-2(gene name)|psi-mi:galla-2(display_short)|uniprotkb:CG7949(orf name) psi-mi:ciao1_drome(display_long)|uniprotkb:CG12797(orf name)|uniprotkb:Ciao1(gene name)|psi-mi:Ciao1(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109720|imex:IM-9552-488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648416.1|flybase:FBgn0036107|ensemblmetazoa:FBgn0036107(gene)|ensemblmetazoa:FBtr0076270(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051301"(cell division)|go:"GO:0097361"(CIA complex)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|rcsb pdb:6TBL|rcsb pdb:6TBN|rcsb pdb:6TC0|dip:DIP-20907N refseq:NP_610996.1|flybase:FBgn0033972|ensemblmetazoa:FBgn0033972(gene)|ensemblmetazoa:FBtr0087460(transcript)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0097361"(CIA complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR028608|interpro:IPR036322|rcsb pdb:6TBL|rcsb pdb:6TBN|rcsb pdb:6TC0 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:aXgg47iVuWLi01lFZYcp4hRJLak7227 rogid:Phz26cdXUQJhXLmnG7x/rOotC8U7227 intact-crc:35CF067428800E12|rigid:TyuJvJcck69oC94G0e/d3mnj5gQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJ39 uniprotkb:A5XCL5 intact:EBI-142535|uniprotkb:Q961A0|intact:EBI-3428985|uniprotkb:R4GRV7|intact:EBI-2108385|uniprotkb:Q7KT44|ensemblmetazoa:FBpp0312552 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 psi-mi:q9vj39_drome(display_long)|uniprotkb:pepCG10602(gene name)|psi-mi:pepCG10602(display_short)|uniprotkb:Dmel\CG10602(gene name synonym)|uniprotkb:MRPL13(gene name synonym)|uniprotkb:mRpL13(gene name synonym)|uniprotkb:CG10602(orf name)|uniprotkb:Dmel_CG10602(orf name) psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109715|imex:IM-9552-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0032721|refseq:NP_609916.5|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0004463"(leukotriene-A4 hydrolase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0043171"(peptide catabolic process)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR036899|interpro:IPR038502|interpro:IPR042097|reactome:R-DME-2142691|reactome:R-DME-6798695|reactome:R-DME-9018676|reactome:R-DME-9018681|reactome:R-DME-9018896|reactome:R-DME-9020265|reactome:R-DME-9023661|ensemblmetazoa:FBgn0032721(gene)|ensemblmetazoa:FBtr0347402(transcript) refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2016/03/15 rogid:lY/LNk0Uowd7gJX5U2DcKbEdfbQ7227 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 intact-crc:E95F5CAE2D7A8612|rigid:1nHwZyS/gNoVTXMljTQGx9HFgjk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1ZB29 uniprotkb:Q7JVZ8 intact:EBI-172165|intact:EBI-2109725|ensemblmetazoa:FBpp0085966|ensemblmetazoa:FBpp0303030 intact:EBI-2108924|ensemblmetazoa:FBpp0085876|ensemblmetazoa:FBpp0311692 psi-mi:a1zb29_drome(display_long)|uniprotkb:Dmel\CG5757(gene name)|psi-mi:Dmel\CG5757(display_short)|uniprotkb:CG5757(orf name)|uniprotkb:Dmel_CG5757(orf name) psi-mi:q7jvz8_drome(display_long)|uniprotkb:GstE11(gene name)|psi-mi:GstE11(display_short)|uniprotkb:Dmel\CG5224(gene name synonym)|uniprotkb:GSTE11(gene name synonym)|uniprotkb:cg5224(gene name synonym)|uniprotkb:gste11(gene name synonym)|uniprotkb:CG5224(orf name)|uniprotkb:Dmel_CG5224(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109728|imex:IM-9552-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611290.3|flybase:FBgn0034299|refseq:NP_001261065.1|ensemblmetazoa:FBgn0034299(gene)|ensemblmetazoa:FBtr0086787(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006227"(dUDP biosynthetic process)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0009041"(uridylate kinase activity)|interpro:IPR018094|interpro:IPR018095|interpro:IPR027417|interpro:IPR039430|reactome:R-DME-499943|ensemblmetazoa:FBtr0329995(transcript) refseq:NP_611339.1|flybase:FBgn0034354|refseq:NP_001286575.1|ensemblmetazoa:FBgn0034354(gene)|ensemblmetazoa:FBtr0086697(transcript)|ensemblmetazoa:FBtr0345628(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:OxwspkQzGEExGA0WVl2aKu5xA7A7227 rogid:c0uFuA7AKzj/F4uJyV7iu2L2iqQ7227 intact-crc:66B81FCDA1CE8DA0|rigid:YLyOQO9CiKavtYpqhpVlogLK3as false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z6R7 uniprotkb:Q8IQK0 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 intact:EBI-2109738|ensemblmetazoa:FBpp0075565 psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:q8iqk0_drome(display_long)|uniprotkb:Dmel\CG10089(gene name)|psi-mi:Dmel\CG10089(display_short)|uniprotkb:CG10089(orf name)|uniprotkb:Dmel_CG10089(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109741|imex:IM-9552-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 refseq:NP_729909.1|flybase:FBgn0036369|ensemblmetazoa:FBgn0036369(gene)|ensemblmetazoa:FBtr0075823(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR020422|interpro:IPR029021 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 rogid:edmm4Pjo73fElgLBnLj/xK0jslo7227 intact-crc:CD9502C8FD63A875|rigid:ovZ9IzCVb3jdlcgMOWhSxZXzr2s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31009 uniprotkb:Q9VUL1 intact:EBI-181495|uniprotkb:Q9VL74|ensemblmetazoa:FBpp0079500|ensemblmetazoa:FBpp0303531|ensemblmetazoa:FBpp0311561 intact:EBI-132528|uniprotkb:Q9VUL0|ensemblmetazoa:FBpp0310803|ensemblmetazoa:FBpp0311740 psi-mi:rs2_drome(display_long)|uniprotkb:CG5920(orf name)|uniprotkb:Protein strings of pearls(gene name synonym)|uniprotkb:RpS2(gene name)|psi-mi:RpS2(display_short)|uniprotkb:sop(gene name synonym) psi-mi:pyrg_drome(display_long)|uniprotkb:CTP synthetase(gene name synonym)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:CTPsyn(gene name)|psi-mi:CTPsyn(display_short)|uniprotkb:CG45070(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109733|imex:IM-9552-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476874.1|flybase:FBgn0004867|refseq:NP_001285785.1|refseq:NP_001260303.1|dip:DIP-18767N|ensemblmetazoa:FBgn0004867(gene)|ensemblmetazoa:FBtr0079905(transcript)|ensemblmetazoa:FBtr0330682(transcript)|ensemblmetazoa:FBtr0345436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0048477"(oogenesis)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-3214858|reactome:R-DME-6791226|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-8876725|reactome:R-DME-975956|reactome:R-DME-975957 refseq:NP_648747.1|refseq:NP_730023.1|refseq:NP_001287067.1|flybase:FBgn0266452|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:6L6Z|rcsb pdb:6LFG|reactome:R-DME-499943|ensemblmetazoa:FBgn0266452(gene)|ensemblmetazoa:FBtr0344431(transcript)|ensemblmetazoa:FBtr0345691(transcript)|go:"GO:0003883"(CTP synthase activity) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:pJQkpqwmeYoJjSWX1kpO0yMZJrg7227 rogid:CO28Z1AFivaEc66iMYDqkzsC2G47227 intact-crc:3CA828088DFCDF9D|rigid:MI7r9hjlQY3FdanNt+2qPNqHI78 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K2I4 uniprotkb:Q94920 intact:EBI-126476|intact:EBI-2109756|ensemblmetazoa:FBpp0075478|ensemblmetazoa:FBpp0075479 intact:EBI-184763|intact:EBI-1631556|uniprotkb:Q94997|uniprotkb:Q9VKP1|uniprotkb:Q29QZ3|ensemblmetazoa:FBpp0079771|ensemblmetazoa:FBpp0079772|ensemblmetazoa:FBpp0100039|ensemblmetazoa:FBpp0293784|ensemblmetazoa:FBpp0304343 psi-mi:q7k2i4_drome(display_long)|uniprotkb:Dmel\CG7768(gene name)|psi-mi:Dmel\CG7768(display_short)|uniprotkb:Dmel_CG7768(orf name)|uniprotkb:CG7768(orf name) psi-mi:vdac_drome(display_long)|uniprotkb:porin(gene name)|psi-mi:porin(display_short)|uniprotkb:POR-1(gene name synonym)|uniprotkb:VDAC(gene name synonym)|uniprotkb:CG6647(orf name)|uniprotkb:Porin(gene name synonym)|uniprotkb:DmVDAC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109760|imex:IM-9552-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_729966.1|flybase:FBgn0036415|ensemblmetazoa:FBgn0036415(gene)|ensemblmetazoa:FBtr0075736(transcript)|ensemblmetazoa:FBtr0075737(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|refseq:NP_648697.1 refseq:NP_001033899.1|refseq:NP_476813.1|refseq:NP_599110.1|flybase:FBgn0004363|refseq:NP_001245961.1|refseq:NP_001260365.1|dip:DIP-17501N|ensemblmetazoa:FBgn0004363(gene)|ensemblmetazoa:FBtr0080182(transcript)|ensemblmetazoa:FBtr0080183(transcript)|ensemblmetazoa:FBtr0100584(transcript)|ensemblmetazoa:FBtr0305260(transcript)|ensemblmetazoa:FBtr0332029(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006811"(ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007291"(sperm individualization)|go:"GO:0007602"(phototransduction)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0016006"(Nebenkern)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046930"(pore complex)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|reactome:R-DME-5205685|reactome:R-DME-70268 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:zCPZJZZammxcBmMYaxhbg223xgc7227 rogid:BzqX5C247xgqsKNPYtJxwti1ul07227 intact-crc:11BDCA52DED35BF8|rigid:gdQGMQcLVCTQcozEZd/B1M1hNzg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P08510 uniprotkb:P12252 intact:EBI-85074|uniprotkb:A4V4Q2|uniprotkb:P08511|uniprotkb:P08512|uniprotkb:P08513|uniprotkb:Q24277|uniprotkb:Q24521|uniprotkb:Q7KUW5|uniprotkb:Q8IQY9|uniprotkb:Q8MT41|uniprotkb:Q9VWZ5|uniprotkb:Q9VWZ9|uniprotkb:Q9VX00|ensemblmetazoa:FBpp0088599|uniprotkb:B6IDJ2|uniprotkb:M9MSC0|uniprotkb:M9NEM4|uniprotkb:M9PF21 intact:EBI-2109749|uniprotkb:O76918|uniprotkb:Q8IRU3|uniprotkb:Q8IRU6|uniprotkb:Q8IRU8|uniprotkb:Q8IRV0|uniprotkb:Q8MRN3|uniprotkb:Q8T8M0|uniprotkb:Q9NF62|uniprotkb:Q9W4S8|uniprotkb:Q9W4T1|intact:EBI-9929134|intact:EBI-3419018|uniprotkb:M9PGD1|uniprotkb:M9PGX1|uniprotkb:Q9W4T0|ensemblmetazoa:FBpp0070487|ensemblmetazoa:FBpp0070489 psi-mi:kcnas_drome(display_long)|uniprotkb:Sh(gene name)|psi-mi:Sh(display_short)|uniprotkb:mns(gene name synonym)|uniprotkb:Protein minisleep(gene name synonym)|uniprotkb:CG12348(orf name) psi-mi:pde4b_drome(display_long)|uniprotkb:Learning/memory process protein(gene name synonym)|uniprotkb:Protein dunce(gene name synonym)|uniprotkb:CG32498(orf name)|uniprotkb:dnc(gene name)|psi-mi:dnc(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109746|imex:IM-9552-490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162788.1|refseq:NP_001188668.1|refseq:NP_523393.3|refseq:NP_728120.1|refseq:NP_728122.1|refseq:NP_728123.1|refseq:NP_728124.1|refseq:NP_996497.1|ensemblmetazoa:FBgn0003380(gene)|ensemblmetazoa:FBtr0089657(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007611"(learning or memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009584"(detection of visible light)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0048675"(axon extension)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1HO2|rcsb pdb:1HO7|reactome:R-DME-1296072|go:"GO:1903351"(cellular response to dopamine)|refseq:NP_001259665.2|refseq:NP_996498.2|flybase:FBgn0003380|refseq:NP_001245727.1|dip:DIP-41151N refseq:NP_726849.1|refseq:NP_726850.1|refseq:NP_726852.2|refseq:NP_726853.2|refseq:NP_726855.1|refseq:NP_726857.1|refseq:NP_726859.2|flybase:FBgn0000479|refseq:NP_001259202.1|refseq:NP_001259203.1|refseq:NP_726851.3|refseq:NP_726854.2|refseq:NP_001259201.1|ensemblmetazoa:FBgn0000479(gene)|ensemblmetazoa:FBtr0070511(transcript)|ensemblmetazoa:FBtr0070513(transcript)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006198"(cAMP catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008306"(associative learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046958"(nonassociative learning)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|interpro:IPR040844 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fEBHWlsCdztu/LP5Ecu0vdPDEVQ7227 rogid:TUgSCl30bxKGGsBDC2OgGjrz0RA7227 intact-crc:E9B15E1F48730C7F|rigid:a+XulU+qknJ1kFzMSVM4pBtYjMg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V6B9 uniprotkb:Q6WAR0 intact:EBI-179307|ensemblmetazoa:FBpp0087063 intact:EBI-2109775 psi-mi:nup54_drome(display_long)|uniprotkb:CG8831(orf name)|uniprotkb:Nup54(gene name)|psi-mi:Nup54(display_short) psi-mi:q6war0_drome(display_long)|uniprotkb:Ntf-2(gene name)|psi-mi:Ntf-2(display_short)|uniprotkb:CG1740(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109779|imex:IM-9552-492 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610783.1|flybase:FBgn0033737|dip:DIP-19285N|ensemblmetazoa:FBgn0033737(gene)|ensemblmetazoa:FBtr0087952(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q9V6B9|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749 flybase:FBgn0031145|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0RSPWkJnRddLDMAOCRvpHWcUlSo7227 rogid:5l26YYePUmYF7AtmMbUgE+YRRg07227 intact-crc:7D6AFF0AAC28CC0D|rigid:6lch/GGzdr7CCXFWcNqGKiteqJg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P61209 uniprotkb:P40945 intact:EBI-123053|uniprotkb:P35676|uniprotkb:Q9VNQ2|uniprotkb:A4V2B1|uniprotkb:A8JNX4|ensemblmetazoa:FBpp0078222|ensemblmetazoa:FBpp0078224|ensemblmetazoa:FBpp0078225|ensemblmetazoa:FBpp0078226|ensemblmetazoa:FBpp0111771|ensemblmetazoa:FBpp0289184|ensemblmetazoa:FBpp0289185|ensemblmetazoa:FBpp0304364 intact:EBI-134336|uniprotkb:Q9V499|ensemblmetazoa:FBpp0088256|ensemblmetazoa:FBpp0305852 psi-mi:arf1_drome(display_long)|uniprotkb:Arf79F(gene name)|psi-mi:Arf79F(display_short)|uniprotkb:ARF1(gene name synonym)|uniprotkb:CG8385(orf name) psi-mi:arf2_drome(display_long)|uniprotkb:Arf102F(gene name)|psi-mi:Arf102F(display_short)|uniprotkb:ARF2(gene name synonym)|uniprotkb:CG11027(orf name)|uniprotkb:dARF II(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109770|imex:IM-9552-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097667.1|refseq:NP_001097668.2|refseq:NP_476955.1|refseq:NP_730757.1|refseq:NP_730758.1|refseq:NP_730759.1|refseq:NP_730760.1|flybase:FBgn0010348|ensemblmetazoa:FBgn0010348(gene)|ensemblmetazoa:FBtr0078573(transcript)|ensemblmetazoa:FBtr0078574(transcript)|ensemblmetazoa:FBtr0078575(transcript)|ensemblmetazoa:FBtr0112858(transcript)|ensemblmetazoa:FBtr0299906(transcript)|ensemblmetazoa:FBtr0299907(transcript)|ensemblmetazoa:FBtr0332054(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002786"(regulation of antibacterial peptide production)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|ensemblmetazoa:FBtr0078571(transcript)|refseq:NP_001262225.1|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032011"(ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048749"(compound eye development)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-DME-1660499|reactome:R-DME-1660514|reactome:R-DME-199992|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438 refseq:NP_524631.1|flybase:FBgn0013749|refseq:NP_001259087.1|ensemblmetazoa:FBgn0013749(gene)|ensemblmetazoa:FBtr0089192(transcript)|ensemblmetazoa:FBtr0333699(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048749"(compound eye development)|go:"GO:0098793"(presynapse)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-DME-5620916|reactome:R-DME-6807878|reactome:R-DME-6811434|dip:DIP-17574N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jll+4R7SmNOLqJPE6qrJ6NJ+awg7227 rogid:P+WH68KHYtv2YP5DlKdx63PcqiE7227 intact-crc:410DBCDB764B4C39|rigid:t1exyELAqtq8XgC7rNIW5Ubb/Nw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40945 uniprotkb:Q2XYK6 intact:EBI-134336|uniprotkb:Q9V499|ensemblmetazoa:FBpp0088256|ensemblmetazoa:FBpp0305852 intact:EBI-2109175|ensemblmetazoa:FBpp0076438 psi-mi:arf2_drome(display_long)|uniprotkb:Arf102F(gene name)|psi-mi:Arf102F(display_short)|uniprotkb:ARF2(gene name synonym)|uniprotkb:CG11027(orf name)|uniprotkb:dARF II(gene name synonym) psi-mi:q2xyk6_drome(display_long)|uniprotkb:CG7197(orf name)|uniprotkb:Arl5(gene name)|psi-mi:Arl5(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109765|imex:IM-9552-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524631.1|flybase:FBgn0013749|refseq:NP_001259087.1|ensemblmetazoa:FBgn0013749(gene)|ensemblmetazoa:FBtr0089192(transcript)|ensemblmetazoa:FBtr0333699(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048749"(compound eye development)|go:"GO:0098793"(presynapse)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-DME-5620916|reactome:R-DME-6807878|reactome:R-DME-6811434|dip:DIP-17574N flybase:FBgn0035866|ensemblmetazoa:FBgn0035866(gene)|ensemblmetazoa:FBtr0076715(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:1903292"(protein localization to Golgi membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:P+WH68KHYtv2YP5DlKdx63PcqiE7227 rogid:bLb2OLL/ojy5YL3omSio0g0HUHA7227 intact-crc:1E91218F5A4BDBFA|rigid:JGRNbI+CfhLLVjaPxtwD9mCuNBQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VP13 uniprotkb:Q8SYC8 intact:EBI-146644|ensemblmetazoa:FBpp0078032 intact:EBI-2109185 psi-mi:q9vp13_drome(display_long)|uniprotkb:CRIF(gene name)|psi-mi:CRIF(display_short)|uniprotkb:Dmel\CG7172(gene name synonym)|uniprotkb:anon-WO0118547.316(gene name synonym)|uniprotkb:dCRIF(gene name synonym)|uniprotkb:Dmel_CG7172(orf name)|uniprotkb:CG7172(orf name)|uniprotkb:Growth arrest and DNA damage-inducible proteins-interacting protein 1(gene name synonym) psi-mi:q8syc8_drome(display_long)|uniprotkb:CG15481(orf name)|uniprotkb:Ski6(gene name)|psi-mi:Ski6(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109793|imex:IM-9552-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649333.1|flybase:FBgn0037102|ensemblmetazoa:FBgn0037102(gene)|ensemblmetazoa:FBtr0078377(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1903705"(positive regulation of production of siRNA involved in RNA interference)|interpro:IPR018472|interpro:IPR043035|reactome:R-DME-5389840|reactome:R-DME-5419276 flybase:FBgn0032487|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LKy1lqXlh6lxGSau1XPARFboxDw7227 rogid:11s6l6e8OGtwBuVKtc3fX82Pztg7227 intact-crc:EEEB3C2C0B39951A|rigid:j/I3jMrPcFvbJ6yCWGD4sTSSCbg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VP13 uniprotkb:A1Z6W5 intact:EBI-146644|ensemblmetazoa:FBpp0078032 intact:EBI-153320|intact:EBI-2109787|ensemblmetazoa:FBpp0088120 psi-mi:q9vp13_drome(display_long)|uniprotkb:CRIF(gene name)|psi-mi:CRIF(display_short)|uniprotkb:Dmel\CG7172(gene name synonym)|uniprotkb:anon-WO0118547.316(gene name synonym)|uniprotkb:dCRIF(gene name synonym)|uniprotkb:Dmel_CG7172(orf name)|uniprotkb:CG7172(orf name)|uniprotkb:Growth arrest and DNA damage-inducible proteins-interacting protein 1(gene name synonym) psi-mi:a1z6w5_drome(display_long)|uniprotkb:Gadd45(gene name)|psi-mi:Gadd45(display_short)|uniprotkb:Gadd45-RA(gene name synonym)|uniprotkb:"BcDNA:RH70774"(gene name synonym)|uniprotkb:D-GADD45(gene name synonym)|uniprotkb:Dmel\CG11086(gene name synonym)|uniprotkb:GADD45(gene name synonym)|uniprotkb:GG1086(gene name synonym)|uniprotkb:gadd45(gene name synonym)|uniprotkb:CG11086(orf name)|uniprotkb:Dmel_CG11086(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109784|imex:IM-9552-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649333.1|flybase:FBgn0037102|ensemblmetazoa:FBgn0037102(gene)|ensemblmetazoa:FBtr0078377(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1903705"(positive regulation of production of siRNA involved in RNA interference)|interpro:IPR018472|interpro:IPR043035|reactome:R-DME-5389840|reactome:R-DME-5419276 refseq:NP_610264.1|flybase:FBgn0033153|ensemblmetazoa:FBgn0033153(gene)|ensemblmetazoa:FBtr0089049(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|reactome:R-DME-6804114 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LKy1lqXlh6lxGSau1XPARFboxDw7227 rogid:RJfbSbn+E5dN6G2bPgQInQyf7fw7227 intact-crc:F2A2A4E0DA49CD94|rigid:8Fpix9YmvOYAi7ah3j62DQv65Ww false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VV76 uniprotkb:Q9VZC9 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 intact:EBI-2108952|ensemblmetazoa:FBpp0073149 psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:q9vzc9_drome(display_long)|uniprotkb:Syx17(gene name)|psi-mi:Syx17(display_short)|uniprotkb:Dm Syx17(gene name synonym)|uniprotkb:DmSyx17(gene name synonym)|uniprotkb:Dmel\CG7452(gene name synonym)|uniprotkb:S17(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:syx17(gene name synonym)|uniprotkb:CG7452(orf name)|uniprotkb:Dmel_CG7452(orf name)|uniprotkb:Stx17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109818|imex:IM-9552-496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 refseq:NP_523926.1|flybase:FBgn0035540|ensemblmetazoa:FBgn0035540(gene)|ensemblmetazoa:FBtr0073293(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR010989(t-SNARE)|interpro:IPR028676 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 rogid:AVwCimBFmfW0aitbEjEpGIjqZWA7227 intact-crc:447D3B8CCD429648|rigid:h+NQI5n3643X7kwr4TtUwZwz+mQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VV76 uniprotkb:Q9W0N6 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 intact:EBI-119356|ensemblmetazoa:FBpp0072503 psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:q9w0n6_drome(display_long)|uniprotkb:Vti1a(gene name)|psi-mi:Vti1a(display_short)|uniprotkb:Vti1(gene name synonym)|uniprotkb:Dmel\CG3279(gene name synonym)|uniprotkb:VTI1(gene name synonym)|uniprotkb:Vti1A(gene name synonym)|uniprotkb:vti1a(gene name synonym)|uniprotkb:CG3279(orf name)|uniprotkb:Dmel_CG3279(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109808|imex:IM-9552-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 refseq:NP_612053.1|flybase:FBgn0260862|ensemblmetazoa:FBgn0260862(gene)|ensemblmetazoa:FBtr0072607(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|reactome:R-DME-6811438|reactome:R-DME-6811440 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 rogid:zNV6ODbviT5S3Xp6A6VYaJA1FCg7227 intact-crc:7E66A1365C2B04C1|rigid:t1lEdABH2Ff1UgRRTZDTVjQirZQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK46 uniprotkb:Q9VV76 intact:EBI-182760|intact:EBI-1630152|ensemblmetazoa:FBpp0080011 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 psi-mi:q9vk46_drome(display_long)|uniprotkb:Yip1d1(gene name)|psi-mi:Yip1d1(display_short)|uniprotkb:Dmel\CG12404(gene name synonym)|uniprotkb:Yip1(gene name synonym)|uniprotkb:CG12404(orf name)|uniprotkb:Dmel_CG12404(orf name) psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109803|imex:IM-9552-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609596.1|flybase:FBgn0032465|dip:DIP-18836N|ensemblmetazoa:FBgn0032465(gene)|ensemblmetazoa:FBtr0080430(transcript)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:1905808"(positive regulation of synapse pruning)|interpro:IPR006977(Yip1 domain) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:JiFe0mxiBay45DuS8UjWtWVUwGw7227 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 intact-crc:1D248472C9CCABA4|rigid:7DBiYyVn1payWSGVQOaCZRNAe98 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24547 uniprotkb:Q9VV76 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109813|imex:IM-9552-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 intact-crc:29625A4798456503|rigid:5Xw5080KcSeyjVfW0h3H9So7Rtg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VV76 uniprotkb:Q7K0X9 intact:EBI-2108443|ensemblmetazoa:FBpp0075124 intact:EBI-167209|ensemblmetazoa:FBpp0078007|ensemblmetazoa:FBpp0078008|intact:EBI-2108484 psi-mi:q9vv76_drome(display_long)|uniprotkb:CG4109(orf name)|uniprotkb:Syx8(gene name)|psi-mi:Syx8(display_short)|uniprotkb:Dm Syx8(gene name synonym)|uniprotkb:DmSyx8(gene name synonym)|uniprotkb:Dmel\CG4109(gene name synonym)|uniprotkb:SYX8(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Dmel_CG4109(orf name) psi-mi:q7k0x9_drome(display_long)|uniprotkb:Syx7(gene name)|psi-mi:Syx7(display_short)|uniprotkb:Aval(gene name synonym)|uniprotkb:Avl(gene name synonym)|uniprotkb:Dm Syx7(gene name synonym)|uniprotkb:DmSyx7(gene name synonym)|uniprotkb:Dmel\CG5081(gene name synonym)|uniprotkb:FCP-C(gene name synonym)|uniprotkb:SYX7(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:avl(gene name synonym)|uniprotkb:braided(gene name synonym)|uniprotkb:dSyn7(gene name synonym)|uniprotkb:syx7(gene name synonym)|uniprotkb:Dmel_CG5081(orf name)|uniprotkb:CG5081(orf name)|uniprotkb:STX7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109798|imex:IM-9552-494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524113.1|flybase:FBgn0036643|ensemblmetazoa:FBgn0036643(gene)|ensemblmetazoa:FBtr0075365(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875 refseq:NP_730632.1|refseq:NP_730633.1|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR010989(t-SNARE)|ensemblmetazoa:FBgn0267849(gene)|ensemblmetazoa:FBtr0078351(transcript)|ensemblmetazoa:FBtr0078352(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0035073"(pupariation)|flybase:FBgn0267849 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:eDH1RCWLs6/F/7Ne2Vj5sGqtUY87227 rogid:i9SFYgLkPP0m5p7BT00RJV6JT/c7227 intact-crc:97328029C19338B1|rigid:To910m1v1etsExSuZ1WFIDFU8Dg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JYV7 uniprotkb:Q9VIZ0 intact:EBI-172044|intact:EBI-2109823|ensemblmetazoa:FBpp0087004 intact:EBI-89092|uniprotkb:Q0IGY9|ensemblmetazoa:FBpp0080704 psi-mi:kad6_drome(display_long)|uniprotkb:Ak6(gene name)|psi-mi:Ak6(display_short)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)|uniprotkb:CG8816(orf name) psi-mi:rpac2_drome(display_long)|uniprotkb:"l(2)37Cg"(gene name)|psi-mi:"l(2)37Cg"(display_short)|uniprotkb:CG10685(orf name)|uniprotkb:AC19(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109827|imex:IM-9552-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610797.1|flybase:FBgn0033754|ensemblmetazoa:FBgn0033754(gene)|ensemblmetazoa:FBtr0087891(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR020618|interpro:IPR027417|reactome:R-DME-499943 refseq:NP_609950.1|flybase:FBgn0086447|ensemblmetazoa:FBgn0086447(gene)|ensemblmetazoa:FBtr0081161(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:kManXClKzWowHUwNykiJ4zQ34987227 rogid:xvsuNplI/+LbRfYGDAnu+9qpOc07227 intact-crc:C1FE8B4BDDF85EF0|rigid:SVHLZ+Icj5urzbqthjXHUNa+XEo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q76NQ9 uniprotkb:O76921 intact:EBI-2109836|ensemblmetazoa:FBpp0290267 intact:EBI-2109832 psi-mi:q76nq9_drome(display_long)|uniprotkb:CG32626(orf name)|uniprotkb:CG11058(gene name synonym)|uniprotkb:CG11065(gene name synonym)|uniprotkb:CG15762(gene name synonym)|uniprotkb:AMPdeam(gene name)|psi-mi:AMPdeam(display_short)|uniprotkb:AMP deam(gene name synonym)|uniprotkb:Dmel\CG32626(gene name synonym)|uniprotkb:Dmel_CG32626(orf name) psi-mi:o76921_drome(display_long)|uniprotkb:Pgcl(gene name)|psi-mi:Pgcl(display_short)|uniprotkb:"EG:EG0001.1"(gene name synonym)|uniprotkb:pcl(gene name synonym)|uniprotkb:CG13374(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109840|imex:IM-9552-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727740.2|flybase:FBgn0052626|ensemblmetazoa:FBgn0052626(gene)|ensemblmetazoa:FBtr0301045(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029749|interpro:IPR032466 flybase:FBgn0011822|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VQNf3TLCbKZTsWKv125TgaSuMzY7227 rogid:A+BN0yJJtGhWSt8/fd+fGvh63n07227 intact-crc:6BEC3CD364D4F215|rigid:xXfL4GZinqJ9GhYaKrNK/RQ3sJc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZS0 uniprotkb:Q9VE50 intact:EBI-131149|ensemblmetazoa:FBpp0083595 intact:EBI-2108573|uniprotkb:Q8SWZ4|ensemblmetazoa:FBpp0083076 psi-mi:q8szs0_drome(display_long)|uniprotkb:Dmel\CG31163(gene name synonym)|uniprotkb:Dmel_CG31163(orf name)|uniprotkb:SKIP(gene name)|psi-mi:SKIP(display_short)|uniprotkb:CG13863(gene name synonym)|uniprotkb:CG13864(gene name synonym)|uniprotkb:CG5736(gene name synonym)|uniprotkb:CG7086(gene name synonym)|uniprotkb:CG7087(gene name synonym)|uniprotkb:CG31163(orf name) psi-mi:gosr1_drome(display_long)|uniprotkb:Gos28(gene name)|psi-mi:Gos28(display_short)|uniprotkb:Probable 28 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:CG7700(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109850|imex:IM-9552-498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732703.1|flybase:FBgn0051163|go:"GO:0007608"(sensory perception of smell)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|ensemblmetazoa:FBtr0084197(transcript)|ensemblmetazoa:FBgn0051163(gene) refseq:NP_650739.2|flybase:FBgn0044871|ensemblmetazoa:FBgn0044871(gene)|ensemblmetazoa:FBtr0083661(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|go:"GO:0048219"(inter-Golgi cisterna vesicle-mediated transport)|interpro:IPR023601|reactome:R-DME-6807878|reactome:R-DME-6811438 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:65jEfG3MxCgYJwA2B8/zdZvMK3s7227 rogid:ZCuGd1ZR4KGcybQN1O75sGFCUxU7227 intact-crc:B8990B3F8894B298|rigid:T7BqotBOKb2VIHixuMglX2LuawE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9U616 uniprotkb:Q9VVP9 intact:EBI-181719|uniprotkb:Q9VP59|ensemblmetazoa:FBpp0078066 intact:EBI-98468|ensemblmetazoa:FBpp0074883 psi-mi:gcsh_drome(display_long)|uniprotkb:ppl(gene name)|psi-mi:ppl(display_short)|uniprotkb:CG7758(orf name)|uniprotkb:Protein pumpless(gene name synonym) psi-mi:q9vvp9_drome(display_long)|uniprotkb:Dmel_CG4306(orf name)|uniprotkb:Dmel\CG4306(gene name)|psi-mi:Dmel\CG4306(display_short)|uniprotkb:CG4306(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109845|imex:IM-9552-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524197.1|flybase:FBgn0027945|dip:DIP-19395N|ensemblmetazoa:FBgn0027945(gene)|ensemblmetazoa:FBtr0078412(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR002930(Glycine cleavage H-protein)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR011053(Single hybrid motif)|interpro:IPR017453(Glycine cleavage H-protein, subgroup)|interpro:IPR033753|reactome:R-DME-389661|reactome:R-DME-6783984 refseq:NP_649038.1|flybase:FBgn0036787|ensemblmetazoa:FBgn0036787(gene)|ensemblmetazoa:FBtr0075117(transcript)|go:"GO:0003839"(gamma-glutamylcyclotransferase activity)|go:"GO:0005576"(extracellular region)|interpro:IPR013024(Butirosin biosynthesis, BtrG-like)|interpro:IPR017939|interpro:IPR036568 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9k5avM/K8XvE/4WTeS+6Rc312487227 rogid:hXRTJDX5i62OjQi5xDNDUEEbJb47227 intact-crc:AA7F8CFB73479F38|rigid:MgVeN2j+iZhO7UhWWZNKw55P2t8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VQD8 uniprotkb:Q9VMH2 intact:EBI-192564|ensemblmetazoa:FBpp0077378|ensemblmetazoa:FBpp0307163 intact:EBI-178420|ensemblmetazoa:FBpp0078831 psi-mi:q9vqd8_drome(display_long)|uniprotkb:Arpc5(gene name)|psi-mi:Arpc5(display_short)|uniprotkb:p16-ARC(gene name synonym)|uniprotkb:ARPC5(gene name synonym)|uniprotkb:ArpC5(gene name synonym)|uniprotkb:Dmel\CG9881(gene name synonym)|uniprotkb:P16-ARC(gene name synonym)|uniprotkb:p16(gene name synonym)|uniprotkb:p16-arc(gene name synonym)|uniprotkb:Dmel_CG9881(orf name)|uniprotkb:CG9881(orf name) psi-mi:q9vmh2_drome(display_long)|uniprotkb:Arpc4(gene name)|psi-mi:Arpc4(display_short)|uniprotkb:Arc-p20(gene name synonym)|uniprotkb:Arc-p20-RA(gene name synonym)|uniprotkb:ARPC4(gene name synonym)|uniprotkb:Arp-p20(gene name synonym)|uniprotkb:"BcDNA:RE43724"(gene name synonym)|uniprotkb:Dmel\CG5972(gene name synonym)|uniprotkb:P-20 ARC(gene name synonym)|uniprotkb:"anon-EST:Posey49"(gene name synonym)|uniprotkb:arc-p20(gene name synonym)|uniprotkb:"l(2)SH1036"(gene name synonym)|uniprotkb:"l(2)SH2 1036"(gene name synonym)|uniprotkb:p20(gene name synonym)|uniprotkb:p20Arc(gene name synonym)|uniprotkb:Dmel_CG5972(orf name)|uniprotkb:CG5972(orf name)|uniprotkb:arpc4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109860|imex:IM-9552-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608693.1|flybase:FBgn0031437|refseq:NP_001259945.1|ensemblmetazoa:FBgn0031437(gene)|ensemblmetazoa:FBtr0077694(transcript)|ensemblmetazoa:FBtr0335170(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-6798695|reactome:R-DME-8856828 refseq:NP_608996.1|flybase:FBgn0284255|ensemblmetazoa:FBgn0284255(gene)|ensemblmetazoa:FBtr0079200(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042060"(wound healing)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-8856828 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:wXJwoDydA6Yc4oN3q9b7kiafbkQ7227 rogid:ADwOxfPaPKGZVuZgI+FU3+4Aq8w7227 intact-crc:FB4AC2B8B1EF1E18|rigid:BqmFzhOxt4dsKrSCEHwcH2SdhHc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31007-1 uniprotkb:P08510 intact:EBI-389394|intact:EBI-6982306|intact:EBI-6982269|intact:EBI-6982467|intact:EBI-6982596|intact:EBI-6982679|intact:EBI-6982507|intact:EBI-6982376|intact:EBI-6982419|intact:EBI-6982541|intact:EBI-6982637|intact:MINT-287920|intact:EBI-6982340|intact:EBI-6982224|ensemblmetazoa:FBpp0073341|ensemblmetazoa:FBpp0089350|ensemblmetazoa:FBpp0290504|ensemblmetazoa:FBpp0305459 intact:EBI-85074|uniprotkb:A4V4Q2|uniprotkb:P08511|uniprotkb:P08512|uniprotkb:P08513|uniprotkb:Q24277|uniprotkb:Q24521|uniprotkb:Q7KUW5|uniprotkb:Q8IQY9|uniprotkb:Q8MT41|uniprotkb:Q9VWZ5|uniprotkb:Q9VWZ9|uniprotkb:Q9VX00|ensemblmetazoa:FBpp0088599|uniprotkb:B6IDJ2|uniprotkb:M9MSC0|uniprotkb:M9NEM4|uniprotkb:M9PF21 psi-mi:p31007-1(display_long)|uniprotkb:Dlg-A(isoform synonym)|uniprotkb:D(isoform synonym)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:kcnas_drome(display_long)|uniprotkb:Sh(gene name)|psi-mi:Sh(display_short)|uniprotkb:mns(gene name synonym)|uniprotkb:Protein minisleep(gene name synonym)|uniprotkb:CG12348(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109855|imex:IM-9552-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-389374(dlg1_drome)|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073485(transcript)|ensemblmetazoa:FBtr0073487(transcript)|ensemblmetazoa:FBtr0301289(transcript)|ensemblmetazoa:FBtr0333261(transcript) refseq:NP_001162788.1|refseq:NP_001188668.1|refseq:NP_523393.3|refseq:NP_728120.1|refseq:NP_728122.1|refseq:NP_728123.1|refseq:NP_728124.1|refseq:NP_996497.1|ensemblmetazoa:FBgn0003380(gene)|ensemblmetazoa:FBtr0089657(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007611"(learning or memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009584"(detection of visible light)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0048675"(axon extension)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1HO2|rcsb pdb:1HO7|reactome:R-DME-1296072|go:"GO:1903351"(cellular response to dopamine)|refseq:NP_001259665.2|refseq:NP_996498.2|flybase:FBgn0003380|refseq:NP_001245727.1|dip:DIP-41151N psi-mi:"MI:0469"(intact) isoform-comment:"Ref.1 (AAA28468) sequence is in conflict in position: 355:S->D." - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:wrup5LHOFRKC8FCNV4IDa1Q+w947227 rogid:fEBHWlsCdztu/LP5Ecu0vdPDEVQ7227 intact-crc:0EEE8D75AB98BE10|rigid:K9fAwlV4z4r3DAFMlU0x7N2M2Mk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWC3 uniprotkb:Q8IH42 intact:EBI-2109329|ensemblmetazoa:FBpp0074575 intact:EBI-2109865|ensemblmetazoa:FBpp0082303 psi-mi:q9vwc3_drome(display_long)|uniprotkb:CG11942(orf name)|uniprotkb:SkpE(gene name)|psi-mi:SkpE(display_short)|uniprotkb:skpE(gene name synonym)|uniprotkb:Dmel_CG11942(orf name)|uniprotkb:Dmel\CG11942(gene name synonym)|uniprotkb:Skp(gene name synonym) psi-mi:q8ih42_drome(display_long)|uniprotkb:Ubc87F(gene name)|psi-mi:Ubc87F(display_short)|uniprotkb:CG9602(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109869|imex:IM-9552-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608359.1|flybase:FBgn0031074|ensemblmetazoa:FBgn0031074(gene)|ensemblmetazoa:FBtr0074806(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296 flybase:FBgn0267383|ensemblmetazoa:FBgn0267383(gene)|ensemblmetazoa:FBtr0082838(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YEd3aJ+3gYv+3VwcM3ewj1R2AUQ7227 rogid:QRIZuGmal3Jqx3wtw6hWjtkHljk7227 intact-crc:17220717C19B27B8|rigid:bzUNwkAd2FJ9zBkrq/sdCBfNQqg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V424 uniprotkb:Q9VXB3 intact:EBI-2109877|ensemblmetazoa:FBpp0081546 intact:EBI-157605|ensemblmetazoa:FBpp0074105|ensemblmetazoa:FBpp0310514 psi-mi:q9v424_drome(display_long)|uniprotkb:CG8208(orf name)|uniprotkb:MBD-like(gene name)|psi-mi:MBD-like(display_short)|uniprotkb:3(gene name synonym)|uniprotkb:Dm Mbd2(gene name synonym)|uniprotkb:DmMbd2(gene name synonym)|uniprotkb:Dmel\CG8208(gene name synonym)|uniprotkb:MBD2(gene name synonym)|uniprotkb:MBD2-3(gene name synonym)|uniprotkb:MBD3(gene name synonym)|uniprotkb:dMBD-like(gene name synonym)|uniprotkb:dMBD2(gene name synonym)|uniprotkb:dMbD2(gene name synonym)|uniprotkb:Dmel_CG8208(orf name) psi-mi:sap30_drome(display_long)|uniprotkb:CG4756(orf name)|uniprotkb:Sap30(gene name)|psi-mi:Sap30(display_short)|uniprotkb:SIN3-associated polypeptide 30(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109874|imex:IM-9552-500 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0027950|refseq:NP_649907.1|ensemblmetazoa:FBgn0027950(gene)|ensemblmetazoa:FBtr0082068(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343 ensemblmetazoa:FBgn0030788(gene)|ensemblmetazoa:FBtr0074331(transcript)|ensemblmetazoa:FBtr0344089(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|reactome:R-DME-3214815|go:"GO:0003677"(DNA binding)|refseq:NP_573162.1|flybase:FBgn0030788|refseq:NP_001285352.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:L86IMKMQHmELPgsj1v1cX6LBJcg7227 rogid:Uk1uZfnU/Td8iHbbHootLO8CZTY7227 intact-crc:422991349477B40F|rigid:8ASAW4Dy6KBoDJt4rGqfLJq1c4Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K148 uniprotkb:Q9VNA5 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109883|imex:IM-9552-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 intact-crc:71A118019B3F6663|rigid:1ciAsloQx8b+qsO2347KbBktdUY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1ZBT5 uniprotkb:Q7KBL8 intact:EBI-90766|intact:EBI-2108649|uniprotkb:Q8SZ54|ensemblmetazoa:FBpp0085609 intact:EBI-96589|intact:EBI-2108658|uniprotkb:Q0IGZ7|ensemblmetazoa:FBpp0087251 psi-mi:med8_drome(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Arc32(gene name synonym)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:CG13867(orf name) psi-mi:med29_drome(display_long)|uniprotkb:ix(gene name)|psi-mi:ix(display_short)|uniprotkb:MED29(gene name synonym)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Protein intersex(gene name synonym)|uniprotkb:CG13201(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109898|imex:IM-9552-502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722456.1|flybase:FBgn0034503|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|ensemblmetazoa:FBtr0086297(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0034503(gene) refseq:NP_610677.1|flybase:FBgn0001276|ensemblmetazoa:FBgn0001276(gene)|ensemblmetazoa:FBtr0088154(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0048804"(imaginal disc-derived female genitalia morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|interpro:IPR021018 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uo2jUy3XqNhJssWFNY2EhtNwsa87227 rogid:/1NFeFBg+2kIpzgPP76GaEbvDxU7227 intact-crc:1E0153C824F434FD|rigid:+VH8CeV9FD4BImPgCGAOV5sU01U false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P26270 uniprotkb:Q9V436 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 intact:EBI-126740|ensemblmetazoa:FBpp0075068 psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:q9v436_drome(display_long)|uniprotkb:Rpn12(gene name)|psi-mi:Rpn12(display_short)|uniprotkb:Dmel\CG4157(gene name synonym)|uniprotkb:S14(gene name synonym)|uniprotkb:dRpn12(gene name synonym)|uniprotkb:p30(gene name synonym)|uniprotkb:Dmel_CG4157(orf name)|uniprotkb:CG4157(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109893|imex:IM-9552-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBgn0028693(gene)|ensemblmetazoa:FBtr0075308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|refseq:NP_648904.1|flybase:FBgn0028693 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 rogid:1LwtWlEcPX/N0cmArYr46dI9Moc7227 intact-crc:0DAD915D266A729A|rigid:qUeoitjQECKhJXc8gsHpKECyYYQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V436 uniprotkb:Q9XYN7 intact:EBI-126740|ensemblmetazoa:FBpp0075068 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:q9v436_drome(display_long)|uniprotkb:Rpn12(gene name)|psi-mi:Rpn12(display_short)|uniprotkb:Dmel\CG4157(gene name synonym)|uniprotkb:S14(gene name synonym)|uniprotkb:dRpn12(gene name synonym)|uniprotkb:p30(gene name synonym)|uniprotkb:Dmel_CG4157(orf name)|uniprotkb:CG4157(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109888|imex:IM-9552-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0028693(gene)|ensemblmetazoa:FBtr0075308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|refseq:NP_648904.1|flybase:FBgn0028693 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:1LwtWlEcPX/N0cmArYr46dI9Moc7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:D21E84095E0B8E5A|rigid:RaV3Pu/EnFVlrYtVuXvWO7QVVQA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12646 uniprotkb:Q9W2M2-1 intact:EBI-223478|uniprotkb:Q27574|uniprotkb:Q27872|uniprotkb:Q27879|uniprotkb:Q27881|uniprotkb:Q9VWE2|uniprotkb:Q9VWE3 intact:EBI-261103|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 psi-mi:g6pd_drome(display_long)|uniprotkb:Zw(gene name)|psi-mi:Zw(display_short)|uniprotkb:G6PD(gene name synonym)|uniprotkb:CG12529(orf name)|uniprotkb:Zwischenferment(gene name synonym) psi-mi:q9w2m2-1(display_long)|uniprotkb:F(isoform synonym)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym)|uniprotkb:CG9364(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109903|imex:IM-9552-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523411.1|refseq:NP_728287.1|flybase:FBgn0004057|refseq:NP_001285456.1|dip:DIP-20748N|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|reactome:R-DME-5628897|reactome:R-DME-71336 intact:EBI-261090(trea_drome)|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qek/GM7bwiBlhVaGkXNWLCgKH/E7227 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 intact-crc:2F760F466F718BBD|rigid:ba0l3NlQv68/KcjfPO+rVRAHCig false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q76NQ9 uniprotkb:Q9VLK3 intact:EBI-2109836|ensemblmetazoa:FBpp0290267 intact:EBI-113759|intact:EBI-1628844|ensemblmetazoa:FBpp0079309|ensemblmetazoa:FBpp0310072 psi-mi:q76nq9_drome(display_long)|uniprotkb:CG32626(orf name)|uniprotkb:CG11058(gene name synonym)|uniprotkb:CG11065(gene name synonym)|uniprotkb:CG15762(gene name synonym)|uniprotkb:AMPdeam(gene name)|psi-mi:AMPdeam(display_short)|uniprotkb:AMP deam(gene name synonym)|uniprotkb:Dmel\CG32626(gene name synonym)|uniprotkb:Dmel_CG32626(orf name) psi-mi:q9vlk3_drome(display_long)|uniprotkb:CG13095(orf name)|uniprotkb:Bace(gene name)|psi-mi:Bace(display_short)|uniprotkb:Dmel\CG13095(gene name synonym)|uniprotkb:anon-WO0140519.142(gene name synonym)|uniprotkb:dBACE(gene name synonym)|uniprotkb:dBace(gene name synonym)|uniprotkb:Dmel_CG13095(orf name)|uniprotkb:DASP2(gene name synonym)|uniprotkb:BACE(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109908|imex:IM-9552-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727740.2|flybase:FBgn0052626|ensemblmetazoa:FBgn0052626(gene)|ensemblmetazoa:FBtr0301045(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029749|interpro:IPR032466 refseq:NP_609235.1|flybase:FBgn0032049|refseq:NP_001285756.1|ensemblmetazoa:FBgn0032049(gene)|ensemblmetazoa:FBtr0079701(transcript)|ensemblmetazoa:FBtr0343427(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:1902944"(aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|reactome:R-DME-2022377|reactome:R-DME-2132295|reactome:R-DME-5683826 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VQNf3TLCbKZTsWKv125TgaSuMzY7227 rogid:ir0zrwd/P9F5jgam+R8veRt1goI7227 intact-crc:D1703E902072DEC0|rigid:Xf3AhS4hQIzjv4jjsSSOh5Xvnlg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XYN7 uniprotkb:Q9VJJ0 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109913|imex:IM-9552-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:31AB0BF9A3887A3D|rigid:p2bnuOhLxcQvpFGKIpW5easl2FM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P18053 uniprotkb:Q9VJJ0 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109923|imex:IM-9552-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:075442875191BB6A|rigid:KQNeEQdxs6KXOZTlKb3L1pHI0e0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9U616 uniprotkb:Q9VJJ0 intact:EBI-181719|uniprotkb:Q9VP59|ensemblmetazoa:FBpp0078066 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:gcsh_drome(display_long)|uniprotkb:ppl(gene name)|psi-mi:ppl(display_short)|uniprotkb:CG7758(orf name)|uniprotkb:Protein pumpless(gene name synonym) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109918|imex:IM-9552-504 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524197.1|flybase:FBgn0027945|dip:DIP-19395N|ensemblmetazoa:FBgn0027945(gene)|ensemblmetazoa:FBtr0078412(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR002930(Glycine cleavage H-protein)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR011053(Single hybrid motif)|interpro:IPR017453(Glycine cleavage H-protein, subgroup)|interpro:IPR033753|reactome:R-DME-389661|reactome:R-DME-6783984 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9k5avM/K8XvE/4WTeS+6Rc312487227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:9734243A5F3A9191|rigid:1rCzbCYr0KGTQfJyDARo1HFDKC4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJJ0 uniprotkb:Q7K148 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109928|imex:IM-9552-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 intact-crc:68082E117D4898B5|rigid:MCU7EgEU6+/6aGBERFyxRxfI7Xo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q76NR0 uniprotkb:Q9VEK4 intact:EBI-2109933|ensemblmetazoa:FBpp0290268 intact:EBI-95240|ensemblmetazoa:FBpp0082879 psi-mi:q76nr0_drome(display_long)|uniprotkb:CG32626(orf name)|uniprotkb:AMP deam(gene name synonym)|uniprotkb:CG11058(gene name synonym)|uniprotkb:CG11065(gene name synonym)|uniprotkb:CG15762(gene name synonym)|uniprotkb:Dmel\CG32626(gene name synonym)|uniprotkb:Dmel_CG32626(orf name)|uniprotkb:AMPdeam(gene name)|psi-mi:AMPdeam(display_short) psi-mi:q9vek4_drome(display_long)|uniprotkb:Dmel\CG5860(gene name)|psi-mi:Dmel\CG5860(display_short)|uniprotkb:FBgn0038506(gene name synonym)|uniprotkb:CG5860(orf name)|uniprotkb:Dmel_CG5860(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109937|imex:IM-9552-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727741.3|flybase:FBgn0052626|ensemblmetazoa:FBgn0052626(gene)|ensemblmetazoa:FBtr0301046(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029749|interpro:IPR032466 refseq:NP_650622.1|flybase:FBgn0038506|ensemblmetazoa:FBgn0038506(gene)|ensemblmetazoa:FBtr0083438(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|reactome:R-DME-2022377|reactome:R-DME-2132295|reactome:R-DME-5683826 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:DT1HDeJjC+hFuhe5Bdg0V9u9O6o7227 rogid:5CLOFvG7X02wQH9ZEmlA9gk1b4g7227 intact-crc:0488516E2F4A216A|rigid:Iqp6XWJNlPVQp6GW7xw2j177exc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q23983 uniprotkb:Q86P91 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 intact:EBI-870760|ensemblmetazoa:FBpp0077022 psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:q86p91_drome(display_long)|uniprotkb:Syx16(gene name)|psi-mi:Syx16(display_short)|uniprotkb:CG1467(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109942|imex:IM-9552-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 flybase:FBgn0031106|ensemblmetazoa:FBgn0031106(gene)|ensemblmetazoa:FBtr0077330(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 rogid:fbF2zl4Do3qLz31Vn+L/HfthV7k7227 intact-crc:A1B7278D8E849907|rigid:QGGKNG0VrZvyx8qXCtH76KzHHag false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P13008 uniprotkb:Q9VBI0 intact:EBI-171405|uniprotkb:A4V0T7|uniprotkb:P10380|uniprotkb:Q0E8P4|uniprotkb:Q9VJ88|uniprotkb:C0PV38|ensemblmetazoa:FBpp0080639|ensemblmetazoa:FBpp0080640|ensemblmetazoa:FBpp0080641|ensemblmetazoa:FBpp0303872|ensemblmetazoa:FBpp0312181 intact:EBI-170896|ensemblmetazoa:FBpp0084341 psi-mi:rs26_drome(display_long)|uniprotkb:RpS26(gene name)|psi-mi:RpS26(display_short)|uniprotkb:CG10305(orf name) psi-mi:q9vbi0_drome(display_long)|uniprotkb:Dmel\CG14543(gene name)|psi-mi:Dmel\CG14543(display_short)|uniprotkb:CG14543(orf name)|uniprotkb:Dmel_CG14543(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109947|imex:IM-9552-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286042.1|refseq:NP_523595.1|refseq:NP_724109.1|refseq:NP_724110.1|flybase:FBgn0261597|refseq:NP_001260537.1|dip:DIP-17487N|ensemblmetazoa:FBgn0261597(gene)|ensemblmetazoa:FBtr0081089(transcript)|ensemblmetazoa:FBtr0081090(transcript)|ensemblmetazoa:FBtr0081091(transcript)|ensemblmetazoa:FBtr0331455(transcript)|ensemblmetazoa:FBtr0346591(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-975956|reactome:R-DME-975957 refseq:NP_651458.1|flybase:FBgn0039404|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|interpro:IPR019398|ensemblmetazoa:FBgn0039404(gene)|ensemblmetazoa:FBtr0084968(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:DeTsUMrxIw8cO3N4R6xN+YSVn8A7227 rogid:4U/x22vL0MotUJ8kxH3pcDr9yrI7227 intact-crc:497F45B8B7B6FEE6|rigid:97OarX8s5muGg0vMWf36wMyZcVU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8MS69 uniprotkb:Q9VBH7 intact:EBI-2108749|ensemblmetazoa:FBpp0078961|ensemblmetazoa:FBpp0309857|ensemblmetazoa:FBpp0309858 intact:EBI-86202|ensemblmetazoa:FBpp0084342|ensemblmetazoa:FBpp0312340 psi-mi:q8ms69_drome(display_long)|uniprotkb:CG9596(orf name)|uniprotkb:Dmel_CG9596(orf name)|uniprotkb:Dmel\CG9596(gene name)|psi-mi:Dmel\CG9596(display_short) psi-mi:q9vbh7_drome(display_long)|uniprotkb:Dmel\CG14544(gene name)|psi-mi:Dmel\CG14544(display_short)|uniprotkb:Dmel_CG14544(orf name)|uniprotkb:CG14544(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109952|imex:IM-9552-506 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995638.1|flybase:FBgn0031832|refseq:NP_001285679.1|refseq:NP_609048.2|ensemblmetazoa:FBgn0031832(gene)|ensemblmetazoa:FBtr0079332(transcript)|ensemblmetazoa:FBtr0343162(transcript)|ensemblmetazoa:FBtr0343163(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|interpro:IPR017423("tRNA (adenine-N(1)-)-methyltransferase, non-catalytic TRM6 subunit") refseq:NP_651461.1|flybase:FBgn0039407|refseq:NP_001303484.1|ensemblmetazoa:FBgn0039407(gene)|ensemblmetazoa:FBtr0084969(transcript)|ensemblmetazoa:FBtr0346731(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|interpro:IPR014816(tRNA methyltransferase complex GCD14 subunit)|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+aQRiNivaBuZ75D7aDm8masiVNg7227 rogid:KN7gMASJ2pxz9XKWZRABwFmqbK87227 intact-crc:446A5EE0EC280766|rigid:zWXLYT+uAHO2gTagG8oneSR2OuE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VPW2 uniprotkb:Q9W2S2 intact:EBI-109341|ensemblmetazoa:FBpp0077618 intact:EBI-107050|ensemblmetazoa:FBpp0071427 psi-mi:q9vpw2_drome(display_long)|uniprotkb:Atg4a(gene name)|psi-mi:Atg4a(display_short)|uniprotkb:Atg4(gene name synonym)|uniprotkb:CG4428(orf name)|uniprotkb:APG4(gene name synonym)|uniprotkb:ATG4(gene name synonym)|uniprotkb:AUT2(gene name synonym)|uniprotkb:Dmel\CG4428(gene name synonym)|uniprotkb:atg4(gene name synonym)|uniprotkb:Dmel_CG4428(orf name) psi-mi:q9w2s2_drome(display_long)|uniprotkb:Atg-8a(gene name synonym)|uniprotkb:Atg8alpha(gene name synonym)|uniprotkb:Atg8a(gene name)|psi-mi:Atg8a(display_short)|uniprotkb:CG1534(gene name synonym)|uniprotkb:ATG8(gene name synonym)|uniprotkb:ATG8a(gene name synonym)|uniprotkb:Atg8(gene name synonym)|uniprotkb:Atg8A(gene name synonym)|uniprotkb:"BcDNA:LD05816"(gene name synonym)|uniprotkb:DmAtg8a(gene name synonym)|uniprotkb:Dmel\CG32672(gene name synonym)|uniprotkb:DrAtg8a(gene name synonym)|uniprotkb:LC3(gene name synonym)|uniprotkb:atg8(gene name synonym)|uniprotkb:atg8A(gene name synonym)|uniprotkb:atg8a(gene name synonym)|uniprotkb:dAtg8a(gene name synonym)|uniprotkb:CG32672(orf name)|uniprotkb:Dmel_CG32672(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109967|imex:IM-9552-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608563.1|flybase:FBgn0031298|ensemblmetazoa:FBgn0031298(gene)|ensemblmetazoa:FBtr0077953(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019786"(Atg8-specific protease activity)|interpro:IPR005078(Peptidase C54)|interpro:IPR038765|reactome:R-DME-1632852 refseq:NP_727447.1|flybase:FBgn0052672|dip:DIP-19734N|ensemblmetazoa:FBgn0052672(gene)|ensemblmetazoa:FBtr0071498(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031386"(protein tag)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0061174"(type I terminal bouton)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|reactome:R-DME-1632852|reactome:R-DME-8854214 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:4rpjGeFxZCEtOrWxCojhNr2FuHE7227 rogid:AQL8hLo1vjdWJ5jCY4wVRcS/AS47227 intact-crc:037A3EC7775DECBC|rigid:ZxK3g8o64JWx5pa7sLNdlwH/Oyw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K1J3 uniprotkb:Q9VPW2 intact:EBI-2109957|ensemblmetazoa:FBpp0312339 intact:EBI-109341|ensemblmetazoa:FBpp0077618 psi-mi:q7k1j3_drome(display_long)|uniprotkb:Atg8b(gene name)|psi-mi:Atg8b(display_short)|uniprotkb:CG12334(orf name) psi-mi:q9vpw2_drome(display_long)|uniprotkb:Atg4a(gene name)|psi-mi:Atg4a(display_short)|uniprotkb:Atg4(gene name synonym)|uniprotkb:CG4428(orf name)|uniprotkb:APG4(gene name synonym)|uniprotkb:ATG4(gene name synonym)|uniprotkb:AUT2(gene name synonym)|uniprotkb:Dmel\CG4428(gene name synonym)|uniprotkb:atg4(gene name synonym)|uniprotkb:Dmel_CG4428(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109962|imex:IM-9552-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0038539|ensemblmetazoa:FBgn0038539(gene)|ensemblmetazoa:FBtr0346730(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016236"(macroautophagy)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0050811"(GABA receptor binding)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071 refseq:NP_608563.1|flybase:FBgn0031298|ensemblmetazoa:FBgn0031298(gene)|ensemblmetazoa:FBtr0077953(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019786"(Atg8-specific protease activity)|interpro:IPR005078(Peptidase C54)|interpro:IPR038765|reactome:R-DME-1632852 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VGNt63y3ijHPeL8AktpTIaIm9HI7227 rogid:4rpjGeFxZCEtOrWxCojhNr2FuHE7227 intact-crc:D012AE08B48D6F52|rigid:7WTgr+FbzpERQe2nwZluXRkXfN0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K3U4 uniprotkb:Q8SZS0 intact:EBI-85838|intact:EBI-2109972|ensemblmetazoa:FBpp0085481 intact:EBI-131149|ensemblmetazoa:FBpp0083595 psi-mi:q7k3u4_drome(display_long)|uniprotkb:Fmo-2(gene name)|psi-mi:Fmo-2(display_short)|uniprotkb:DmFMO-2(gene name synonym)|uniprotkb:Dmel\CG3174(gene name synonym)|uniprotkb:Dmfmo2(gene name synonym)|uniprotkb:fmo2(gene name synonym)|uniprotkb:CG3174(orf name)|uniprotkb:Dmel_CG3174(orf name) psi-mi:q8szs0_drome(display_long)|uniprotkb:Dmel\CG31163(gene name synonym)|uniprotkb:Dmel_CG31163(orf name)|uniprotkb:SKIP(gene name)|psi-mi:SKIP(display_short)|uniprotkb:CG13863(gene name synonym)|uniprotkb:CG13864(gene name synonym)|uniprotkb:CG5736(gene name synonym)|uniprotkb:CG7086(gene name synonym)|uniprotkb:CG7087(gene name synonym)|uniprotkb:CG31163(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109976|imex:IM-9552-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610217.1|flybase:FBgn0033079|ensemblmetazoa:FBgn0033079(gene)|ensemblmetazoa:FBtr0086148(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044237"(cellular metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR020946|interpro:IPR036188 refseq:NP_732703.1|flybase:FBgn0051163|go:"GO:0007608"(sensory perception of smell)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|ensemblmetazoa:FBtr0084197(transcript)|ensemblmetazoa:FBgn0051163(gene) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:q3OMK3ZgXQpZQkzdqyn36nXr95U7227 rogid:65jEfG3MxCgYJwA2B8/zdZvMK3s7227 intact-crc:396DD8078CAC676A|rigid:N3lq7Juv9evsexyj7HdpXMQkJaY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q76NQ9 uniprotkb:Q8IGU5 intact:EBI-2109836|ensemblmetazoa:FBpp0290267 intact:EBI-466654|ensemblmetazoa:FBpp0084796 psi-mi:q76nq9_drome(display_long)|uniprotkb:CG32626(orf name)|uniprotkb:CG11058(gene name synonym)|uniprotkb:CG11065(gene name synonym)|uniprotkb:CG15762(gene name synonym)|uniprotkb:AMPdeam(gene name)|psi-mi:AMPdeam(display_short)|uniprotkb:AMP deam(gene name synonym)|uniprotkb:Dmel\CG32626(gene name synonym)|uniprotkb:Dmel_CG32626(orf name) psi-mi:q8igu5_drome(display_long)|uniprotkb:FipoQ(gene name)|psi-mi:FipoQ(display_short)|uniprotkb:CG2010(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109986|imex:IM-9552-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727740.2|flybase:FBgn0052626|ensemblmetazoa:FBgn0052626(gene)|ensemblmetazoa:FBtr0301045(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029749|interpro:IPR032466 flybase:FBgn0039667|ensemblmetazoa:FBgn0039667(gene)|ensemblmetazoa:FBtr0085428(transcript)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|interpro:IPR039940 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VQNf3TLCbKZTsWKv125TgaSuMzY7227 rogid:08sGTujKzT1RyNWeTykmgp+dN4E7227 intact-crc:A3E6AE99C699B22B|rigid:f4shGR62iHGOUm+YWtQ83ed3VBs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q6NR18 uniprotkb:P02572 intact:EBI-2108814 intact:EBI-110368|uniprotkb:Q24228|uniprotkb:Q540X3|uniprotkb:Q9V9J4|ensemblmetazoa:FBpp0085365 psi-mi:q6nr18_drome(display_long)|uniprotkb:Pld(gene name)|psi-mi:Pld(display_short)|uniprotkb:CG12110(orf name) psi-mi:act2_drome(display_long)|uniprotkb:Act42A(gene name)|psi-mi:Act42A(display_short)|uniprotkb:CG12051(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109981|imex:IM-9552-508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0286511|go:"GO:0004630"(phospholipase D activity)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007349"(cellularization)|go:"GO:0007602"(phototransduction)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048215"(positive regulation of Golgi vesicle fusion to target membrane)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR036871 refseq:NP_523625.1|flybase:FBgn0000043|dip:DIP-20355N|ensemblmetazoa:FBgn0000043(gene)|ensemblmetazoa:FBtr0086029(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0035060"(brahma complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o6ATxLbRQIQbVWqBeUlQCXkKktM7227 rogid:YeeXgsuRY2BQ3DVxG7MuVmol+bo7227 intact-crc:68CBFF6A175C5F94|rigid:ujG12SRxx3tHHs0isgtsAelDbPA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VVL7 uniprotkb:Q9VVE5 intact:EBI-110434|ensemblmetazoa:FBpp0074906|ensemblmetazoa:FBpp0304195 intact:EBI-142162|intact:EBI-1630443|uniprotkb:Q8MQZ1|uniprotkb:A8JNU7|uniprotkb:A8JNU8|uniprotkb:Q26276|ensemblmetazoa:FBpp0075045 psi-mi:q9vvl7_drome(display_long)|uniprotkb:E3(gene name)|psi-mi:E3(display_short)|uniprotkb:Dmel\CG7430(gene name synonym)|uniprotkb:CG7430(orf name)|uniprotkb:Dmel_CG7430(orf name) psi-mi:msir6_drome(display_long)|uniprotkb:CG32169(orf name)|uniprotkb:Rbp6(gene name)|psi-mi:Rbp6(display_short)|uniprotkb:RRM6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109991|imex:IM-9552-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649017.1|flybase:FBgn0036762|refseq:NP_001262000.1|ensemblmetazoa:FBgn0036762(gene)|ensemblmetazoa:FBtr0075140(transcript)|ensemblmetazoa:FBtr0331810(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|reactome:R-DME-204174|reactome:R-DME-389661|reactome:R-DME-5362517|reactome:R-DME-6783984|reactome:R-DME-70268|reactome:R-DME-70895|reactome:R-DME-71064|reactome:R-DME-71403 refseq:NP_001097631.1|refseq:NP_001097632.1|refseq:NP_730245.2|flybase:FBgn0260943|dip:DIP-19056N|ensemblmetazoa:FBgn0260943(gene)|ensemblmetazoa:FBtr0075285(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0048864"(stem cell development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|reactome:R-DME-9013418 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Z1ikpHda8Rx9t/G3w2o9rhqbxE07227 rogid:Q4dWJg7cfrPLHIl8P3rQMMpWZyU7227 intact-crc:6E81574B325D672E|rigid:+QxVrIaaNbSPI1TSXToYefIAhdM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W385 uniprotkb:Q9VFF0 intact:EBI-2109999|uniprotkb:Q9GQQ7|ensemblmetazoa:FBpp0071283 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 psi-mi:frda_drome(display_long)|uniprotkb:fh(gene name)|psi-mi:fh(display_short)|uniprotkb:CG8971(orf name) psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2109996|imex:IM-9552-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511094.1|flybase:FBgn0030092|ensemblmetazoa:FBgn0030092(gene)|ensemblmetazoa:FBtr0071348(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010039"(response to iron ion)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045998"(positive regulation of ecdysteroid biosynthetic process)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|reactome:R-DME-1362409 refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ckn5jZ0i3E8xBBck1JaHgBgXTa47227 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 intact-crc:5229478D38E400E2|rigid:a2AMeMN/3zz/dEeJ/pcrsndDP70 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VMP9 uniprotkb:Q9VG73 intact:EBI-2110008|ensemblmetazoa:FBpp0078734|ensemblmetazoa:FBpp0078735|ensemblmetazoa:FBpp0297903|ensemblmetazoa:FBpp0297906|ensemblmetazoa:FBpp0304065 intact:EBI-151485|ensemblmetazoa:FBpp0082066 psi-mi:gnpi_drome(display_long)|uniprotkb:Oscillin(gene name)|psi-mi:Oscillin(display_short)|uniprotkb:Glucosamine-6-phosphate deaminase(gene name synonym)|uniprotkb:Gnpda1(gene name synonym)|uniprotkb:Oscillin homolog(gene name synonym)|uniprotkb:CG6957(orf name) psi-mi:ilf2_drome(display_long)|uniprotkb:CG5641(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110005|imex:IM-9552-510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608938.1|refseq:NP_723092.1|flybase:FBgn0031717|refseq:NP_001245894.1|refseq:NP_001245897.1|refseq:NP_001260101.1|ensemblmetazoa:FBgn0031717(gene)|ensemblmetazoa:FBtr0079101(transcript)|ensemblmetazoa:FBtr0079102(transcript)|ensemblmetazoa:FBtr0307060(transcript)|ensemblmetazoa:FBtr0307063(transcript)|ensemblmetazoa:FBtr0331675(transcript)|go:"GO:0004342"(glucosamine-6-phosphate deaminase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006043"(glucosamine catabolic process)|go:"GO:0006044"(N-acetylglucosamine metabolic process)|go:"GO:0006046"(N-acetylglucosamine catabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0019262"(N-acetylneuraminate catabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004547(Glucosamine-6-phosphate isomerase)|interpro:IPR006148(Glucosamine/galactosamine-6-phosphate isomerase)|interpro:IPR018321|interpro:IPR037171|reactome:R-DME-70171 refseq:NP_650196.1|flybase:FBgn0038046|ensemblmetazoa:FBgn0038046(gene)|ensemblmetazoa:FBtr0082594(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006561(DZF)|interpro:IPR043519|reactome:R-DME-6798695 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:QI1wXj9TjM7OSbNI6tZMwK5IP+g7227 rogid:/ZKDWkNOiaK5tLcP245s07ShqOQ7227 intact-crc:93156859C4E527CE|rigid:j01wUPap6BMn6EwvZfwzEnB7vNI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z6R7 uniprotkb:Q7JWS8 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 intact:EBI-74904|intact:EBI-2108936|ensemblmetazoa:FBpp0084561|ensemblmetazoa:FBpp0084562|ensemblmetazoa:FBpp0084563 psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:q7jws8_drome(display_long)|uniprotkb:Mtl(gene name)|psi-mi:Mtl(display_short)|uniprotkb:5588(gene name synonym)|uniprotkb:Dmel\CG5588(gene name synonym)|uniprotkb:MTL(gene name synonym)|uniprotkb:Mig2-like(gene name synonym)|uniprotkb:Mt1(gene name synonym)|uniprotkb:Rac(gene name synonym)|uniprotkb:Rac GTPase(gene name synonym)|uniprotkb:Rac-like(gene name synonym)|uniprotkb:dMig-2(gene name synonym)|uniprotkb:mtl(gene name synonym)|uniprotkb:Dmel_CG5588(orf name)|uniprotkb:CG5588(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110032|imex:IM-9552-512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 refseq:NP_524533.1|refseq:NP_733222.1|refseq:NP_733223.1|flybase:FBgn0039532|ensemblmetazoa:FBgn0039532(gene)|ensemblmetazoa:FBtr0085191(transcript)|ensemblmetazoa:FBtr0085192(transcript)|ensemblmetazoa:FBtr0085193(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007254"(JNK cascade)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035099"(hemocyte migration)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 rogid:x5LZmisdfK+Fu3EyxmAzuYFzMSQ7227 intact-crc:B81DF79B20C971C8|rigid:R0Mntz8P2L2yTY86smu5JSoJiDk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q5U127 uniprotkb:Q9VFF0 intact:EBI-2108819|ensemblmetazoa:FBpp0293514 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 psi-mi:q5u127_drome(display_long)|uniprotkb:CG6169(orf name)|uniprotkb:"BEST:LD07107"(gene name synonym)|uniprotkb:DCp2p(gene name synonym)|uniprotkb:Dmel\CG6169(gene name synonym)|uniprotkb:LD07107(gene name synonym)|uniprotkb:dDCP2(gene name synonym)|uniprotkb:dDcp(gene name synonym)|uniprotkb:dDcp2(gene name synonym)|uniprotkb:dcp2(gene name synonym)|uniprotkb:Dmel_CG6169(orf name)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:Dcp2(gene name synonym) psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110027|imex:IM-9552-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0036534|refseq:NP_001246776.1|ensemblmetazoa:FBgn0036534(gene)|ensemblmetazoa:FBtr0304975(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0045495"(pole plasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0051015"(actin filament binding)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|reactome:R-DME-430039|reactome:R-DME-450385|reactome:R-DME-450513 refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:tHmfiFVFS9g1efAZYjOeLj0o4wg7227 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 intact-crc:1257DC2737298126|rigid:vyJt0vyP/HbA3MSUGlQTNrCwG7M false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG73 uniprotkb:Q0KIB3 intact:EBI-151485|ensemblmetazoa:FBpp0082066 intact:EBI-118590|intact:EBI-2110014|ensemblmetazoa:FBpp0078318|ensemblmetazoa:FBpp0078319 psi-mi:ilf2_drome(display_long)|uniprotkb:CG5641(orf name) psi-mi:q0kib3_drome(display_long)|uniprotkb:Hat1(gene name)|psi-mi:Hat1(display_short)|uniprotkb:CG2051(orf name)|uniprotkb:Dmel\CG2051(gene name synonym)|uniprotkb:dmHAG409(gene name synonym)|uniprotkb:Dmel_CG2051(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110017|imex:IM-9552-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650196.1|flybase:FBgn0038046|ensemblmetazoa:FBgn0038046(gene)|ensemblmetazoa:FBtr0082594(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006561(DZF)|interpro:IPR043519|reactome:R-DME-6798695 refseq:NP_649587.1|flybase:FBgn0037376|refseq:NP_731006.1|ensemblmetazoa:FBgn0037376(gene)|ensemblmetazoa:FBtr0078669(transcript)|ensemblmetazoa:FBtr0078670(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/ZKDWkNOiaK5tLcP245s07ShqOQ7227 rogid:fYEUaPO2rHMI5PAoMLV8kx1nUgA7227 intact-crc:3F8DB5F4E3DCDE87|rigid:OBzFPa7NWCznwFGTDBCLD40w2EQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG73 uniprotkb:Q8SXG7 intact:EBI-151485|ensemblmetazoa:FBpp0082066 intact:EBI-118303|uniprotkb:Q9VQZ9|ensemblmetazoa:FBpp0077144 psi-mi:ilf2_drome(display_long)|uniprotkb:CG5641(orf name) psi-mi:q8sxg7_drome(display_long)|uniprotkb:Secp43(gene name)|psi-mi:Secp43(display_short)|uniprotkb:Dmel\CG15440(gene name synonym)|uniprotkb:cg15440(gene name synonym)|uniprotkb:tRNA selenocysteine-associated protein 1(gene name synonym)|uniprotkb:CG15440(orf name)|uniprotkb:Dmel_CG15440(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110022|imex:IM-9552-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650196.1|flybase:FBgn0038046|ensemblmetazoa:FBgn0038046(gene)|ensemblmetazoa:FBtr0082594(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006561(DZF)|interpro:IPR043519|reactome:R-DME-6798695 refseq:NP_608837.2|flybase:FBgn0031607|ensemblmetazoa:FBgn0031607(gene)|ensemblmetazoa:FBtr0077454(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034510|interpro:IPR035979|interpro:IPR041085 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/ZKDWkNOiaK5tLcP245s07ShqOQ7227 rogid:WBXfxCWvCmLGxGUyM1ldkyZhvug7227 intact-crc:1F53DF413C79D406|rigid:gbzuMAvoC29mDqcRKUKAtAhfQ7k false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z6R7 uniprotkb:Q9VWF4 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 intact:EBI-77109|intact:EBI-2110037|uniprotkb:Q95TD9|ensemblmetazoa:FBpp0074510|ensemblmetazoa:FBpp0304757 psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:dusk4_drome(display_long)|uniprotkb:MKP-4(gene name)|psi-mi:MKP-4(display_short)|uniprotkb:CG14211(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110040|imex:IM-9552-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 refseq:NP_608332.2|flybase:FBgn0031044|refseq:NP_001259717.1|ensemblmetazoa:FBgn0031044(gene)|ensemblmetazoa:FBtr0074741(transcript)|ensemblmetazoa:FBtr0332481(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|interpro:IPR020422|interpro:IPR029021 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2017/05/05 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 rogid:41bExgEvdPNNON1SIrk/HlUi3LY7227 intact-crc:520F192854CB12D2|rigid:lU2duhWRa0UhHeIGqv5gkxzAX/Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P20353 uniprotkb:A1Z6R7 intact:EBI-119189|uniprotkb:Q9VS04|ensemblmetazoa:FBpp0076643 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 psi-mi:gnai_drome(display_long)|uniprotkb:Galphai(gene name)|psi-mi:Galphai(display_short)|uniprotkb:G-OA65C(gene name synonym)|uniprotkb:G-ialpha65A(gene name synonym)|uniprotkb:"Guanine nucleotide-binding protein G(i) subunit alpha 65A"(gene name synonym)|uniprotkb:CG10060(orf name) psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110045|imex:IM-9552-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477502.1|flybase:FBgn0001104|ensemblmetazoa:FBgn0001104(gene)|ensemblmetazoa:FBtr0076934(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032291"(axon ensheathment in central nervous system)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045179"(apical cortex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060857"(establishment of glial blood-brain barrier)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-DME-170670|reactome:R-DME-392170|reactome:R-DME-400042|reactome:R-DME-418594|reactome:R-DME-9009391|dip:DIP-17262N refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:8aWPqFXD0lfIYSuPXAYso82oNRo7227 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 intact-crc:C34EBAFE060C75C8|rigid:JrQiAsvqMcoZqz7ikwSL906lTT4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P16378-1 uniprotkb:A1Z6R7 intact:EBI-197476|ensemblmetazoa:FBpp0087360|ensemblmetazoa:FBpp0087361|ensemblmetazoa:FBpp0089316 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 psi-mi:p16378-1(display_long)|uniprotkb:Galphao(gene name)|psi-mi:Galphao(display_short)|uniprotkb:G-oa47A(gene name synonym)|uniprotkb:G-oalpha47A(gene name synonym)|uniprotkb:"Guanine nucleotide-binding protein G(o) subunit alpha 47A"(gene name synonym)|uniprotkb:CG2204(orf name)|uniprotkb:I(isoform synonym) psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110050|imex:IM-9552-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-197464(gnao_drome)|ensemblmetazoa:FBgn0001122(gene)|ensemblmetazoa:FBtr0088265(transcript)|ensemblmetazoa:FBtr0088266(transcript)|ensemblmetazoa:FBtr0088272(transcript) refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hI0MEgKRVTOvsn9vCOs1jAXPiCc7227 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 intact-crc:5A9999D335EAA7D5|rigid:dFbCZEmWxF3G6E+JZkgyfLtjJG4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24192 uniprotkb:A1Z6R7 intact:EBI-2110055|uniprotkb:Q541G3|uniprotkb:Q9U5D4|uniprotkb:Q9VHC9|ensemblmetazoa:FBpp0081602 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 psi-mi:rhol_drome(display_long)|uniprotkb:Drac3(gene name synonym)|uniprotkb:RhoL(gene name)|psi-mi:RhoL(display_short)|uniprotkb:CG9366(orf name) psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110059|imex:IM-9552-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524292.1|flybase:FBgn0014380|ensemblmetazoa:FBgn0014380(gene)|ensemblmetazoa:FBtr0082124(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007498"(mesoderm development)|go:"GO:0007516"(hemocyte development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:04vIIOyGzh9DRImNyDyDMxaJtuM7227 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 intact-crc:0659DFD037948F68|rigid:pgQParnPks4alKR3/muE5q0KJnA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K1Q7 uniprotkb:P40320 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 intact:EBI-203634|uniprotkb:Q0E8V3|uniprotkb:Q9VPJ2|uniprotkb:Q9VPJ3|uniprotkb:Q9VPJ4|uniprotkb:Q9VPJ5|ensemblmetazoa:FBpp0088445|ensemblmetazoa:FBpp0088446|ensemblmetazoa:FBpp0088448|ensemblmetazoa:FBpp0088449|ensemblmetazoa:FBpp0088450|ensemblmetazoa:FBpp0088926 psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:metk_drome(display_long)|uniprotkb:Sam-S(gene name)|psi-mi:Sam-S(display_short)|uniprotkb:SamS(gene name synonym)|uniprotkb:CG2674(orf name)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:"M(2)21AB"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110064|imex:IM-9552-514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 refseq:NP_524923.1|refseq:NP_722593.1|refseq:NP_722594.1|refseq:NP_722595.1|refseq:NP_722596.1|refseq:NP_722597.1|refseq:NP_722598.1|refseq:NP_722599.1|refseq:NP_722600.1|refseq:NP_995602.1|flybase:FBgn0005278|dip:DIP-18340N|ensemblmetazoa:FBgn0005278(gene)|ensemblmetazoa:FBtr0089429(transcript)|ensemblmetazoa:FBtr0089430(transcript)|ensemblmetazoa:FBtr0089432(transcript)|ensemblmetazoa:FBtr0089433(transcript)|ensemblmetazoa:FBtr0089434(transcript)|ensemblmetazoa:FBtr0089437(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 rogid:COUl0nv83GMZge7edbQNfqgn2dQ7227 intact-crc:C27FCE06F935EEC8|rigid:1BCAaemdHGPGUoebwyWPJEMUsU8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VH66 uniprotkb:Q7JWS8 intact:EBI-184344|ensemblmetazoa:FBpp0081617|ensemblmetazoa:FBpp0312544 intact:EBI-74904|intact:EBI-2108936|ensemblmetazoa:FBpp0084561|ensemblmetazoa:FBpp0084562|ensemblmetazoa:FBpp0084563 psi-mi:q9vh66_drome(display_long)|uniprotkb:Dmel\CG8500(gene name)|psi-mi:Dmel\CG8500(display_short)|uniprotkb:CG8500-RA(gene name synonym)|uniprotkb:Q9VH66(gene name synonym)|uniprotkb:CG8500(orf name)|uniprotkb:Dmel_CG8500(orf name) psi-mi:q7jws8_drome(display_long)|uniprotkb:Mtl(gene name)|psi-mi:Mtl(display_short)|uniprotkb:5588(gene name synonym)|uniprotkb:Dmel\CG5588(gene name synonym)|uniprotkb:MTL(gene name synonym)|uniprotkb:Mig2-like(gene name synonym)|uniprotkb:Mt1(gene name synonym)|uniprotkb:Rac(gene name synonym)|uniprotkb:Rac GTPase(gene name synonym)|uniprotkb:Rac-like(gene name synonym)|uniprotkb:dMig-2(gene name synonym)|uniprotkb:mtl(gene name synonym)|uniprotkb:Dmel_CG5588(orf name)|uniprotkb:CG5588(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110079|imex:IM-9552-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649948.1|flybase:FBgn0037754|refseq:NP_001303452.1|ensemblmetazoa:FBtr0082139(transcript)|ensemblmetazoa:FBtr0347364(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|ensemblmetazoa:FBgn0037754(gene) refseq:NP_524533.1|refseq:NP_733222.1|refseq:NP_733223.1|flybase:FBgn0039532|ensemblmetazoa:FBgn0039532(gene)|ensemblmetazoa:FBtr0085191(transcript)|ensemblmetazoa:FBtr0085192(transcript)|ensemblmetazoa:FBtr0085193(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007254"(JNK cascade)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035099"(hemocyte migration)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nazv4Xl/PZzCBZnusM0GXlaqBEE7227 rogid:x5LZmisdfK+Fu3EyxmAzuYFzMSQ7227 intact-crc:A632A44BEA07516B|rigid:uPwff2KnAwpAK4ugaA071nqG7ks false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T498 intact:EBI-2108411 intact:EBI-98032|uniprotkb:A8JV42|intact:EBI-1629037|uniprotkb:Q95TL0|uniprotkb:Q9VX23|ensemblmetazoa:FBpp0291975 - psi-mi:gap2_drome(display_long)|uniprotkb:raskol(gene name)|psi-mi:raskol(display_short)|uniprotkb:CG42684(orf name) psi-mi:q8img7_drome(display_short)|psi-mi:EBI-2108411(display_long)|uniprotkb:Dmel_CG11525(orf name)|uniprotkb:CycG(gene name)|psi-mi:CycG(display_short)|uniprotkb:CG11525(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110069|imex:IM-9552-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097012.1|refseq:NP_573240.1|flybase:FBgn0261570|ensemblmetazoa:FBgn0261570(gene)|ensemblmetazoa:FBtr0302835(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045179"(apical cortex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR039360|dip:DIP-19744N uniprotkb:Q8IMG7(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:MoaEJehOhhNKwO/BjKpMD7tslJQ7227 rogid:GwDM/XQ/mtqkftw2t9BwmojZmFA7227 intact-crc:F3C391FE11AFC924|rigid:0rYUlO54BotqgT98Z57YprmTcWE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XYN7 uniprotkb:Q7K148 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 intact:EBI-116800|ensemblmetazoa:FBpp0087319|ensemblmetazoa:FBpp0087320|intact:EBI-2108295 psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:q7k148_drome(display_long)|uniprotkb:Prosbeta5(gene name)|psi-mi:Prosbeta5(display_short)|uniprotkb:Pros-beta-5(gene name synonym)|uniprotkb:Beta-5(gene name synonym)|uniprotkb:Dmel\CG12323(gene name synonym)|uniprotkb:LD08717(gene name synonym)|uniprotkb:PSMB5(gene name synonym)|uniprotkb:Pros b5(gene name synonym)|uniprotkb:anon-WO0118547.116(gene name synonym)|uniprotkb:beta-5(gene name synonym)|uniprotkb:beta5(gene name synonym)|uniprotkb:dbeta5(gene name synonym)|uniprotkb:CG12323(orf name)|uniprotkb:Dmel_CG12323(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110074|imex:IM-9552-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N ensemblmetazoa:FBtr0088224(transcript)|ensemblmetazoa:FBtr0088225(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|ensemblmetazoa:FBgn0029134(gene)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-983168|refseq:NP_652014.1|refseq:NP_724974.1|flybase:FBgn0029134 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 rogid:yLhjb2ZyJB5BO+keV1Leh5+/LKY7227 intact-crc:F911122BD6A8E496|rigid:JWOU7ESFEU0vnEk+myY9JCy08AQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q960X4 uniprotkb:Q9VSL2 intact:EBI-124365|uniprotkb:O97425|ensemblmetazoa:FBpp0305388|ensemblmetazoa:FBpp0070636 intact:EBI-146058|ensemblmetazoa:FBpp0076348 psi-mi:tip60_drome(display_long)|uniprotkb:Tip60(gene name)|psi-mi:Tip60(display_short)|uniprotkb:CG6121(orf name) psi-mi:q9vsl2_drome(display_long)|uniprotkb:DmGSTO3(gene name synonym)|uniprotkb:Dmel\CG6776(gene name synonym)|uniprotkb:GSTO3(gene name synonym)|uniprotkb:T14(gene name synonym)|uniprotkb:Dmel_CG6776(orf name)|uniprotkb:CG6776(orf name)|uniprotkb:GstO3(gene name)|psi-mi:GstO3(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110094|imex:IM-9552-516 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572151.1|flybase:FBgn0026080|refseq:NP_001259234.1|ensemblmetazoa:FBtr0070668(transcript)|ensemblmetazoa:FBtr0333186(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:1990188"(euchromatin binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|reactome:R-DME-2559586|reactome:R-DME-5693548|reactome:R-DME-5693565|reactome:R-DME-9018519|ensemblmetazoa:FBgn0026080(gene) refseq:NP_648234.1|flybase:FBgn0035904|ensemblmetazoa:FBgn0035904(gene)|ensemblmetazoa:FBtr0076622(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0045174"("glutathione dehydrogenase (ascorbate) activity")|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR005442(Glutathione S-transferase, omega-class)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|reactome:R-DME-156590|reactome:R-DME-196836 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YZeS6GSo2rydZfUJDo1L43+TPX07227 rogid:0IarZqx5lf0bztqSQyfrtAAS7zY7227 intact-crc:05698A691EDAC0F5|rigid:nusZaGs2hkXGYdm/JMLrYjhq2+s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXW3 uniprotkb:Q9VT75 intact:EBI-166026|ensemblmetazoa:FBpp0073835|uniprotkb:Q960Y1 intact:EBI-133584|ensemblmetazoa:FBpp0076077|ensemblmetazoa:FBpp0076078|ensemblmetazoa:FBpp0076079|ensemblmetazoa:FBpp0076080|ensemblmetazoa:FBpp0076081 psi-mi:q9vxw3_drome(display_long)|uniprotkb:Dmel\CG12608(gene name)|psi-mi:Dmel\CG12608(display_short)|uniprotkb:CG12608(orf name)|uniprotkb:Dmel_CG12608(orf name) psi-mi:q9vt75_drome(display_long)|uniprotkb:vnc(gene name)|psi-mi:vnc(display_short)|uniprotkb:Ard1(gene name synonym)|uniprotkb:ARD1(gene name synonym)|uniprotkb:DmAAF50178(gene name synonym)|uniprotkb:Dmel\CG11989(gene name synonym)|uniprotkb:NAA10(gene name synonym)|uniprotkb:Naa10(gene name synonym)|uniprotkb:ard1(gene name synonym)|uniprotkb:dArd1(gene name synonym)|uniprotkb:"l(3)67BDk"(gene name synonym)|uniprotkb:Dmel_CG11989(orf name)|uniprotkb:11(gene name synonym)|uniprotkb:dNaa10(gene name synonym)|uniprotkb:CG11989(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110084|imex:IM-9552-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0074018(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|ensemblmetazoa:FBgn0030630(gene)|refseq:NP_573019.1|flybase:FBgn0030630 refseq:NP_648378.1|refseq:NP_729581.1|refseq:NP_729582.1|refseq:NP_729583.1|refseq:NP_729584.1|flybase:FBgn0263251|ensemblmetazoa:FBgn0263251(gene)|ensemblmetazoa:FBtr0076348(transcript)|ensemblmetazoa:FBtr0076349(transcript)|ensemblmetazoa:FBtr0076350(transcript)|ensemblmetazoa:FBtr0076351(transcript)|ensemblmetazoa:FBtr0076352(transcript)|go:"GO:0016573"(histone acetylation)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031248"(protein acetyltransferase complex)|go:"GO:0031415"(NatA complex)|go:"GO:0048477"(oogenesis)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cnH75G6LB7REYv2Sa/ySy1JROho7227 rogid:o3xmQfTimj+I6AK4peQ6/M6eaXU7227 intact-crc:C77BD32D8A5A0173|rigid:qY2stOLKsvEofD+MVrwBrP4P4Sw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P26686 uniprotkb:Q8IFW3 intact:EBI-133905|uniprotkb:Q24252|uniprotkb:Q26277|uniprotkb:Q8IH12|uniprotkb:Q8ING7|uniprotkb:Q8ING8|uniprotkb:Q8ING9|uniprotkb:Q8MZ66|uniprotkb:Q8T0I0|uniprotkb:Q9VFT0|uniprotkb:Q9VFT1|uniprotkb:A4V2U2|uniprotkb:E1JIK1|uniprotkb:E1JIK2|uniprotkb:E1JIK3|uniprotkb:E4NKI6 intact:EBI-2109201 psi-mi:srr55_drome(display_long)|uniprotkb:B52(gene name)|psi-mi:B52(display_short)|uniprotkb:CG10851(orf name)|uniprotkb:Protein enhancer of deformed(gene name synonym)|uniprotkb:52 kDa bracketing protein(gene name synonym)|uniprotkb:B52 protein(gene name synonym)|uniprotkb:"E(Dfd)"(gene name synonym)|uniprotkb:RS55(gene name synonym)|uniprotkb:SR55(gene name synonym) psi-mi:q8ifw3_drome(display_long)|uniprotkb:CG8383(orf name)|uniprotkb:Pnn(gene name)|psi-mi:Pnn(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110089|imex:IM-9552-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163603.1|refseq:NP_001163604.1|refseq:NP_788665.1|refseq:NP_788666.1|refseq:NP_788668.1|refseq:NP_788669.1|refseq:NP_788670.1|flybase:FBgn0004587|refseq:NP_001014619.2|refseq:NP_788667.2|refseq:NP_788671.2|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0044819"(mitotic G1/S transition checkpoint signaling)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051607"(defense response to virus)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter) flybase:FBgn0037737|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR039853 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:W93o6QSYDl81WHhwaxV+WaOxo+c7227 rogid:PRyU9fdEfKBFeQgOwSNOYGXdnwA7227 intact-crc:7E4E227670461E48|rigid:vaSJEfhTayiPlDMJBFpFGtAhbxE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q960X4 uniprotkb:P84249 intact:EBI-124365|uniprotkb:O97425|ensemblmetazoa:FBpp0305388|ensemblmetazoa:FBpp0070636 intact:EBI-120797|uniprotkb:A4V466|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q9V3W4 psi-mi:tip60_drome(display_long)|uniprotkb:Tip60(gene name)|psi-mi:Tip60(display_short)|uniprotkb:CG6121(orf name) psi-mi:h33_drome(display_long)|uniprotkb:His3.3A(gene name)|psi-mi:His3.3A(display_short)|uniprotkb:CG5825(orf name)|uniprotkb:His3.3B(gene name)|psi-mi:His3.3B(display_short)|uniprotkb:CG8989(orf name)|uniprotkb:H3.A/B(gene name synonym)|uniprotkb:H3.3Q(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110099|imex:IM-9552-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572151.1|flybase:FBgn0026080|refseq:NP_001259234.1|ensemblmetazoa:FBtr0070668(transcript)|ensemblmetazoa:FBtr0333186(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:1990188"(euchromatin binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|reactome:R-DME-2559586|reactome:R-DME-5693548|reactome:R-DME-5693565|reactome:R-DME-9018519|ensemblmetazoa:FBgn0026080(gene) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0006334"(nucleosome assembly)|refseq:NP_511095.1|refseq:NP_523479.1|refseq:NP_727314.1|refseq:NP_788892.1|flybase:FBgn0014857|flybase:FBgn0004828|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|go:"GO:0031492"(nucleosomal DNA binding)|reactome:R-DME-201722|reactome:R-DME-212300|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-427359|reactome:R-DME-427413|reactome:R-DME-5578749|reactome:R-DME-73777|reactome:R-DME-8936459|reactome:R-DME-983231|refseq:NP_001259374.1|refseq:NP_001260082.1|refseq:NP_723056.2|mint:MINT-840146 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:YZeS6GSo2rydZfUJDo1L43+TPX07227 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I7227 intact-crc:E7C567E58590D732|rigid:kfuIjM6oF4C1GD43SOHxrARSo5Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VHL2 uniprotkb:Q9V426 intact:EBI-102936|ensemblmetazoa:FBpp0081401 intact:EBI-82525|ensemblmetazoa:FBpp0080277|ensemblmetazoa:FBpp0080278|ensemblmetazoa:FBpp0080279|ensemblmetazoa:FBpp0080280|intact:EBI-3405793 psi-mi:q9vhl2_drome(display_long)|uniprotkb:CG8351(orf name)|uniprotkb:Cct7(gene name synonym)|uniprotkb:Dmel\CG8351(gene name synonym)|uniprotkb:Q9VHL2_DROME(gene name synonym)|uniprotkb:TCP1eta(gene name synonym)|uniprotkb:TCPeta(gene name synonym)|uniprotkb:Tcp-1-eta1(gene name synonym)|uniprotkb:tcp-1eta(gene name synonym)|uniprotkb:tcp1eta(gene name synonym)|uniprotkb:Dmel_CG8351(orf name)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:Tcp-1eta(gene name synonym)|uniprotkb:T-cp1eta(gene name synonym)|uniprotkb:TCP1-eta(gene name synonym)|uniprotkb:CCT-eta(gene name synonym) psi-mi:q9v426_drome(display_long)|uniprotkb:vig(gene name)|psi-mi:vig(display_short)|uniprotkb:Dmel_CG4170(orf name)|uniprotkb:"BG:DS00929.13"(gene name synonym)|uniprotkb:Dmel\CG4170(gene name synonym)|uniprotkb:"EP(2)0812"(gene name synonym)|uniprotkb:VIG(gene name synonym)|uniprotkb:Vig(gene name synonym)|uniprotkb:CG4170(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110104|imex:IM-9552-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649835.1|flybase:FBgn0037632|ensemblmetazoa:FBgn0037632(gene)|ensemblmetazoa:FBtr0081918(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|reactome:R-DME-390471|reactome:R-DME-6814122|reactome:R-DME-9013418|reactome:R-DME-9013422 ensemblmetazoa:FBgn0024183(gene)|ensemblmetazoa:FBtr0080718(transcript)|ensemblmetazoa:FBtr0080719(transcript)|ensemblmetazoa:FBtr0080720(transcript)|ensemblmetazoa:FBtr0080721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR039764|reactome:R-DME-114608|refseq:NP_523572.1|refseq:NP_723896.1|refseq:NP_723897.1|refseq:NP_723898.1|flybase:FBgn0024183 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:wRbc8Yrczcc64aX0+ui6yrLLAKw7227 rogid:di+ekbJKilqKbXC1f0Pa4pdwubs7227 intact-crc:2AEE502BB0B98B9E|rigid:tJuOb1m4+d3HE+QeX2ExmsfbgYs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9Y166 uniprotkb:A5XCL5 intact:EBI-2110109|ensemblmetazoa:FBpp0082215|ensemblmetazoa:FBpp0082216|ensemblmetazoa:FBpp0311942 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 psi-mi:q9y166_drome(display_long)|uniprotkb:CG8790(orf name)|uniprotkb:BcDNA.GH02431(gene name synonym)|uniprotkb:Dic1(gene name)|psi-mi:Dic1(display_short)|uniprotkb:"BcDNA:GH02431"(gene name synonym)|uniprotkb:DmDic1p(gene name synonym)|uniprotkb:Dmel\CG8790(gene name synonym)|uniprotkb:Dmel_CG8790(orf name) psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110113|imex:IM-9552-518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650279.1|refseq:NP_731793.1|flybase:FBgn0027610|refseq:NP_001287313.1|ensemblmetazoa:FBgn0027610(gene)|ensemblmetazoa:FBtr0082747(transcript)|ensemblmetazoa:FBtr0082748(transcript)|ensemblmetazoa:FBtr0346113(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|reactome:R-DME-1614517|reactome:R-DME-428643|reactome:R-DME-70263 refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fUrNqhx9uR5q5Pvjep0vG13KkPw7227 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 intact-crc:0835274A1EA50499|rigid:9kMqoZ68+50d0Xi17zOkui4gwBQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JVZ8 uniprotkb:Q9VG96 intact:EBI-2108924|ensemblmetazoa:FBpp0085876|ensemblmetazoa:FBpp0311692 intact:EBI-117276|uniprotkb:Q541F8|uniprotkb:Q9TX90|ensemblmetazoa:FBpp0082043 psi-mi:q7jvz8_drome(display_long)|uniprotkb:GstE11(gene name)|psi-mi:GstE11(display_short)|uniprotkb:Dmel\CG5224(gene name synonym)|uniprotkb:GSTE11(gene name synonym)|uniprotkb:cg5224(gene name synonym)|uniprotkb:gste11(gene name synonym)|uniprotkb:CG5224(orf name)|uniprotkb:Dmel_CG5224(orf name) psi-mi:gstd4_drome(display_long)|uniprotkb:GstD4(gene name)|psi-mi:GstD4(display_short)|uniprotkb:gstD23(gene name synonym)|uniprotkb:CG11512(orf name)|uniprotkb:GSTD4-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110123|imex:IM-9552-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_611339.1|flybase:FBgn0034354|refseq:NP_001286575.1|ensemblmetazoa:FBgn0034354(gene)|ensemblmetazoa:FBtr0086697(transcript)|ensemblmetazoa:FBtr0345628(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282 ensemblmetazoa:FBgn0010040(gene)|ensemblmetazoa:FBtr0082571(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|refseq:NP_524913.1|flybase:FBgn0010040|dip:DIP-19902N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:c0uFuA7AKzj/F4uJyV7iu2L2iqQ7227 rogid:WnxIOP1ON8XMcxemAdfgL9YKN2I7227 intact-crc:D6ADCF7EDE26EACB|rigid:6CsbXwAJ7LMsCN7eWd81TIOaMW0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SXB1 uniprotkb:Q9Y162 intact:EBI-2108683|ensemblmetazoa:FBpp0084340 intact:EBI-161914|ensemblmetazoa:FBpp0074278|ensemblmetazoa:FBpp0309628 psi-mi:q8sxb1_drome(display_long)|uniprotkb:Vps2(gene name)|psi-mi:Vps2(display_short)|uniprotkb:vps2(gene name synonym)|uniprotkb:CG14542(orf name) psi-mi:q9y162_drome(display_long)|uniprotkb:Vps4(gene name)|psi-mi:Vps4(display_short)|uniprotkb:3B1(gene name synonym)|uniprotkb:"BcDNA:GH02678"(gene name synonym)|uniprotkb:DmBcDNA.GH02678(gene name synonym)|uniprotkb:Dmel\CG6842(gene name synonym)|uniprotkb:Dvps4(gene name synonym)|uniprotkb:Vps4B(gene name synonym)|uniprotkb:"bcDNA:GH02678"(gene name synonym)|uniprotkb:dvps4(gene name synonym)|uniprotkb:vps4(gene name synonym)|uniprotkb:Dmel_CG6842(orf name)|uniprotkb:BcDNA.GH02678(gene name synonym)|uniprotkb:CG6842(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110118|imex:IM-9552-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0039402|ensemblmetazoa:FBgn0039402(gene)|ensemblmetazoa:FBtr0084967(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|interpro:IPR005024(Snf7) refseq:NP_573258.1|ensemblmetazoa:FBgn0283469(gene)|ensemblmetazoa:FBtr0074504(transcript)|ensemblmetazoa:FBtr0342787(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0007033"(vacuole organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045463"(R8 cell development)|go:"GO:0045470"(R8 cell-mediated photoreceptor organization)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR031255|interpro:IPR036181|interpro:IPR041569|reactome:R-DME-9668328|refseq:NP_001285396.1|flybase:FBgn0283469 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:539QTjLR85Yu+kvkcKUPlGhvjYg7227 rogid:ztNVeFtIOGStdx60lDjss+ONTrs7227 intact-crc:97C67EDCFDC81800|rigid:bexaWXLUMIgAzX2WNeOOcnihd2k false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG94 uniprotkb:Q9VG96 intact:EBI-152218|uniprotkb:Q9TX93|ensemblmetazoa:FBpp0082045 intact:EBI-117276|uniprotkb:Q541F8|uniprotkb:Q9TX90|ensemblmetazoa:FBpp0082043 psi-mi:gstd6_drome(display_long)|uniprotkb:GstD6(gene name)|psi-mi:GstD6(display_short)|uniprotkb:gstD25(gene name synonym)|uniprotkb:CG4423(orf name)|uniprotkb:GSTD6-6(gene name synonym) psi-mi:gstd4_drome(display_long)|uniprotkb:GstD4(gene name)|psi-mi:GstD4(display_short)|uniprotkb:gstD23(gene name synonym)|uniprotkb:CG11512(orf name)|uniprotkb:GSTD4-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110128|imex:IM-9552-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524915.1|flybase:FBgn0010042|ensemblmetazoa:FBgn0010042(gene)|ensemblmetazoa:FBtr0082573(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|dip:DIP-19904N ensemblmetazoa:FBgn0010040(gene)|ensemblmetazoa:FBtr0082571(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|refseq:NP_524913.1|flybase:FBgn0010040|dip:DIP-19902N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yLMZqw8pFrpfCW23h/8ZasBuKYE7227 rogid:WnxIOP1ON8XMcxemAdfgL9YKN2I7227 intact-crc:9DD5BFBBEA478E53|rigid:XWuzMILOOMXH51COxqgyjjVU138 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IH02 uniprotkb:P12982 intact:EBI-2109045|ensemblmetazoa:FBpp0112342 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 psi-mi:q8ih02_drome(display_long)|uniprotkb:CG32264(orf name)|uniprotkb:CG10860(gene name)|psi-mi:CG10860(display_short) psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110133|imex:IM-9552-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0052264|ensemblmetazoa:FBgn0052264(gene)|ensemblmetazoa:FBtr0113430(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|interpro:IPR004018(RPEL repeat) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:aLrXZsmZQbbKBKh23YAPfHddBCc7227 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 intact-crc:FAF0BC6CE3558491|rigid:aH1s0C6cSE5uDJNRoW/H1Z0R0R4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V464 uniprotkb:P84249 intact:EBI-136881|ensemblmetazoa:FBpp0074715|ensemblmetazoa:FBpp0291576 intact:EBI-120797|uniprotkb:A4V466|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q9V3W4 psi-mi:asf1_drome(display_long)|uniprotkb:asf1(gene name)|psi-mi:asf1(display_short)|uniprotkb:CG9383(orf name)|uniprotkb:Anti-silencing function protein 1(gene name synonym)|uniprotkb:dASF1(gene name synonym)|uniprotkb:Replication-coupling assembly factor subunit ASF1(gene name synonym) psi-mi:h33_drome(display_long)|uniprotkb:His3.3A(gene name)|psi-mi:His3.3A(display_short)|uniprotkb:CG5825(orf name)|uniprotkb:His3.3B(gene name)|psi-mi:His3.3B(display_short)|uniprotkb:CG8989(orf name)|uniprotkb:H3.A/B(gene name synonym)|uniprotkb:H3.3Q(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110138|imex:IM-9552-520 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189131.1|refseq:NP_524163.1|flybase:FBgn0029094|ensemblmetazoa:FBgn0029094(gene)|ensemblmetazoa:FBtr0074947(transcript)|ensemblmetazoa:FBtr0302381(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035059"(RCAF complex)|go:"GO:0042393"(histone binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|dip:DIP-22309N go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0006334"(nucleosome assembly)|refseq:NP_511095.1|refseq:NP_523479.1|refseq:NP_727314.1|refseq:NP_788892.1|flybase:FBgn0014857|flybase:FBgn0004828|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|go:"GO:0031492"(nucleosomal DNA binding)|reactome:R-DME-201722|reactome:R-DME-212300|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-427359|reactome:R-DME-427413|reactome:R-DME-5578749|reactome:R-DME-73777|reactome:R-DME-8936459|reactome:R-DME-983231|refseq:NP_001259374.1|refseq:NP_001260082.1|refseq:NP_723056.2|mint:MINT-840146 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UbHBQKyGG2iEdIFPw8tsDGa0qNo7227 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I7227 intact-crc:56C28FB81AC0BBB6|rigid:iLlaE4/9TpOAJ4Iz19JTS5YgFIY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9U616 uniprotkb:Q9V9X4 intact:EBI-181719|uniprotkb:Q9VP59|ensemblmetazoa:FBpp0078066 intact:EBI-148365|ensemblmetazoa:FBpp0085169|ensemblmetazoa:FBpp0085170|ensemblmetazoa:FBpp0306623 psi-mi:gcsh_drome(display_long)|uniprotkb:ppl(gene name)|psi-mi:ppl(display_short)|uniprotkb:CG7758(orf name)|uniprotkb:Protein pumpless(gene name synonym) psi-mi:mtna_drome(display_long)|uniprotkb:CG11334(orf name)|uniprotkb:S-methyl-5-thioribose-1-phosphate isomerase(gene name synonym)|uniprotkb:Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110143|imex:IM-9552-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524197.1|flybase:FBgn0027945|dip:DIP-19395N|ensemblmetazoa:FBgn0027945(gene)|ensemblmetazoa:FBtr0078412(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009249"(protein lipoylation)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR002930(Glycine cleavage H-protein)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR011053(Single hybrid motif)|interpro:IPR017453(Glycine cleavage H-protein, subgroup)|interpro:IPR033753|reactome:R-DME-389661|reactome:R-DME-6783984 refseq:NP_651868.1|refseq:NP_733430.1|flybase:FBgn0039849|refseq:NP_001263144.1|ensemblmetazoa:FBgn0039849(gene)|ensemblmetazoa:FBtr0085808(transcript)|ensemblmetazoa:FBtr0085809(transcript)|ensemblmetazoa:FBtr0334556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0046523"(S-methyl-5-thioribose-1-phosphate isomerase activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR005251(Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase)|interpro:IPR011559(Initiation factor 2B alpha/beta/delta)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|reactome:R-DME-1237112 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9k5avM/K8XvE/4WTeS+6Rc312487227 rogid:s+pt75/KF3qgyGfdBh84q3hnlKg7227 intact-crc:D887E0F94BF10CCB|rigid:vS07dTA+bGgVZYyij0wex+YzFDw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97067 uniprotkb:Q9VFF0 intact:EBI-197419|uniprotkb:Q8MR09|uniprotkb:Q9VI42|intact:EBI-197428|ensemblmetazoa:FBpp0290838|ensemblmetazoa:FBpp0311968 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 psi-mi:pth2_drome(display_long)|uniprotkb:CG1307(orf name) psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110153|imex:IM-9552-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287202.1|refseq:NP_649675.2|flybase:FBgn0026566|dip:DIP-17218N|ensemblmetazoa:FBgn0026566(gene)|ensemblmetazoa:FBtr0301623(transcript)|ensemblmetazoa:FBtr0346140(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476 refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:FIVtb+hVFAggFkSwKx3Ei8PfpYI7227 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 intact-crc:F1B11BF6AA882DE9|rigid:ry4qcj3HK7h+3xqwgQIoCk1kcfg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VH66 intact:EBI-2110158 intact:EBI-184344|ensemblmetazoa:FBpp0081617|ensemblmetazoa:FBpp0312544 - psi-mi:q9vh66_drome(display_long)|uniprotkb:Dmel\CG8500(gene name)|psi-mi:Dmel\CG8500(display_short)|uniprotkb:CG8500-RA(gene name synonym)|uniprotkb:Q9VH66(gene name synonym)|uniprotkb:CG8500(orf name)|uniprotkb:Dmel_CG8500(orf name) psi-mi:q8ip95_drome(display_short)|psi-mi:EBI-2110158(display_long)|uniprotkb:Patsas(gene name)|psi-mi:Patsas(display_short)|uniprotkb:Dmel_CG6618(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110162|imex:IM-9552-522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649948.1|flybase:FBgn0037754|refseq:NP_001303452.1|ensemblmetazoa:FBtr0082139(transcript)|ensemblmetazoa:FBtr0347364(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|ensemblmetazoa:FBgn0037754(gene) uniprotkb:Q8IP95(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nazv4Xl/PZzCBZnusM0GXlaqBEE7227 rogid:dVFpkubEy3B5ezcMT2ekSEblM7g7227 intact-crc:68756E33FD0A9D5B|rigid:8CuMFblGfDF0Te8ZwFlrfFKC61U false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95029 uniprotkb:Q9V3P9 intact:EBI-162713|uniprotkb:O97431|uniprotkb:Q5U121|ensemblmetazoa:FBpp0086719 intact:EBI-137137|ensemblmetazoa:FBpp0080206 psi-mi:catl_drome(display_long)|uniprotkb:Cp1(gene name)|psi-mi:Cp1(display_short)|uniprotkb:"fs(2)50Ca"(gene name synonym)|uniprotkb:CG6692(orf name)|uniprotkb:Cysteine proteinase 1(gene name synonym) psi-mi:q9v3p9_drome(display_long)|uniprotkb:Cpr35B(gene name)|psi-mi:Cpr35B(display_short)|uniprotkb:"BG:DS06238.4"(gene name synonym)|uniprotkb:DS06283.4(gene name synonym)|uniprotkb:DmelCpr35B(gene name synonym)|uniprotkb:Dmel\CG3474(gene name synonym)|uniprotkb:Dmel_CG3474(orf name)|uniprotkb:CG3474(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110148|imex:IM-9552-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523735.2|refseq:NP_725347.1|flybase:FBgn0013770|ensemblmetazoa:FBgn0013770(gene)|ensemblmetazoa:FBtr0087593(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006955"(immune response)|go:"GO:0007586"(digestion)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0045169"(fusome)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|interpro:IPR039417|reactome:R-DME-1474228|reactome:R-DME-1592389|reactome:R-DME-2132295|reactome:R-DME-6798695|reactome:R-DME-8939242 refseq:NP_609713.1|flybase:FBgn0028871|ensemblmetazoa:FBgn0028871(gene)|ensemblmetazoa:FBtr0080633(transcript)|go:"GO:0008010"(structural constituent of chitin-based larval cuticle)|go:"GO:0031012"(extracellular matrix)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0062129"(chitin-based extracellular matrix)|interpro:IPR000618(Insect cuticle protein)|interpro:IPR031311 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sjFuIB9g8e76z0Ie7wag4aTFLv47227 rogid:bSvL5nLjcNm/S3HPv1jGh7uUdhE7227 intact-crc:B63E3DC1BE8CF97C|rigid:YKw/zkPxYaoNvomt0+6bOidpgoM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFF0 uniprotkb:Q9VFV9 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 intact:EBI-121507|ensemblmetazoa:FBpp0082219|ensemblmetazoa:FBpp0082220|ensemblmetazoa:FBpp0082221|ensemblmetazoa:FBpp0082222|ensemblmetazoa:FBpp0082223 psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:q9vfv9_drome(display_long)|uniprotkb:Droj2(gene name)|psi-mi:Droj2(display_short)|uniprotkb:CG8863(orf name)|uniprotkb:DnaJL2A(gene name synonym)|uniprotkb:anon-WO0118547.404(gene name synonym)|uniprotkb:Dmel_CG8863(orf name)|uniprotkb:DROJ2(gene name synonym)|uniprotkb:Dmel\CG8863(gene name synonym)|uniprotkb:Hsp40(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110182|imex:IM-9552-524 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 refseq:NP_650283.1|refseq:NP_731804.1|refseq:NP_731805.1|refseq:NP_731806.1|refseq:NP_731807.1|flybase:FBgn0038145|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|ensemblmetazoa:FBgn0038145(gene)|reactome:R-DME-3371497|ensemblmetazoa:FBtr0082751(transcript)|ensemblmetazoa:FBtr0082752(transcript)|ensemblmetazoa:FBtr0082753(transcript)|ensemblmetazoa:FBtr0082754(transcript)|ensemblmetazoa:FBtr0082755(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 rogid:2SIHKEbZ/eKMfB2gLDRtjBat+V47227 intact-crc:CD889BD1E6EC3DD4|rigid:HxSHlNl9Bl7p+dk7fxSrstufRiw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VH48 uniprotkb:P84249 intact:EBI-128534|uniprotkb:Q86NL6|ensemblmetazoa:FBpp0081628|ensemblmetazoa:FBpp0305840 intact:EBI-120797|uniprotkb:A4V466|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q9V3W4 psi-mi:carm1_drome(display_long)|uniprotkb:Art4(gene name)|psi-mi:Art4(display_short)|uniprotkb:Carmer(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator arginine methyltransferase for EcR/Usp(gene name synonym)|uniprotkb:CG5358(orf name) psi-mi:h33_drome(display_long)|uniprotkb:His3.3A(gene name)|psi-mi:His3.3A(display_short)|uniprotkb:CG5825(orf name)|uniprotkb:His3.3B(gene name)|psi-mi:His3.3B(display_short)|uniprotkb:CG8989(orf name)|uniprotkb:H3.A/B(gene name synonym)|uniprotkb:H3.3Q(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110172|imex:IM-9552-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649963.1|flybase:FBgn0037770|ensemblmetazoa:FBgn0037770(gene)|ensemblmetazoa:FBtr0082150(transcript)|ensemblmetazoa:FBtr0333687(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0120142"(positive regulation of ecdysone receptor-mediated signaling pathway)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025799|interpro:IPR029063|reactome:R-DME-400206|reactome:R-DME-9018519|reactome:R-DME-9707564|refseq:NP_001262445.1 go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0006334"(nucleosome assembly)|refseq:NP_511095.1|refseq:NP_523479.1|refseq:NP_727314.1|refseq:NP_788892.1|flybase:FBgn0014857|flybase:FBgn0004828|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|go:"GO:0031492"(nucleosomal DNA binding)|reactome:R-DME-201722|reactome:R-DME-212300|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-427359|reactome:R-DME-427413|reactome:R-DME-5578749|reactome:R-DME-73777|reactome:R-DME-8936459|reactome:R-DME-983231|refseq:NP_001259374.1|refseq:NP_001260082.1|refseq:NP_723056.2|mint:MINT-840146 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ZJG19kp46r4bkLGuBhMx66fvIHg7227 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I7227 intact-crc:BC52D7DD2FCCBE7D|rigid:Hi+TjPldi8Y2UwBQI3OpQATJf3o false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFF0 uniprotkb:Q0E924 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110177|imex:IM-9552-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 intact-crc:C462BFFA39D6EF81|rigid:3veWzs1jU3egusJeZKVUhiUdFls false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VH66 uniprotkb:P16378 intact:EBI-184344|ensemblmetazoa:FBpp0081617|ensemblmetazoa:FBpp0312544 intact:EBI-197464|intact:EBI-1630404|uniprotkb:A4UZB6|uniprotkb:A4UZC1|uniprotkb:P16377|uniprotkb:P16707|uniprotkb:B7FF70|uniprotkb:Q8IGI5|uniprotkb:Q540V8|uniprotkb:Q9V5L5|uniprotkb:Q9V5L6|ensemblmetazoa:FBpp0087360|ensemblmetazoa:FBpp0087361|ensemblmetazoa:FBpp0089316 psi-mi:q9vh66_drome(display_long)|uniprotkb:Dmel\CG8500(gene name)|psi-mi:Dmel\CG8500(display_short)|uniprotkb:CG8500-RA(gene name synonym)|uniprotkb:Q9VH66(gene name synonym)|uniprotkb:CG8500(orf name)|uniprotkb:Dmel_CG8500(orf name) psi-mi:gnao_drome(display_long)|uniprotkb:Galphao(gene name)|psi-mi:Galphao(display_short)|uniprotkb:G-oa47A(gene name synonym)|uniprotkb:G-oalpha47A(gene name synonym)|uniprotkb:"Guanine nucleotide-binding protein G(o) subunit alpha 47A"(gene name synonym)|uniprotkb:CG2204(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110167|imex:IM-9552-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649948.1|flybase:FBgn0037754|refseq:NP_001303452.1|ensemblmetazoa:FBtr0082139(transcript)|ensemblmetazoa:FBtr0347364(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|ensemblmetazoa:FBgn0037754(gene) refseq:NP_523684.2|refseq:NP_724934.1|refseq:NP_724935.1|refseq:NP_788304.1|refseq:NP_788305.1|refseq:NP_788306.1|refseq:NP_788307.1|refseq:NP_995801.1|refseq:NP_995802.1|flybase:FBgn0001122|dip:DIP-17224N|ensemblmetazoa:FBgn0001122(gene)|ensemblmetazoa:FBtr0088265(transcript)|ensemblmetazoa:FBtr0088266(transcript)|ensemblmetazoa:FBtr0088272(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0007507"(heart development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032291"(axon ensheathment in central nervous system)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-DME-4086398 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nazv4Xl/PZzCBZnusM0GXlaqBEE7227 rogid:hI0MEgKRVTOvsn9vCOs1jAXPiCc7227 intact-crc:123681C3F002C649|rigid:LjUD6LMQA4PhcVLxBSfRwpDCq9k false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P26270 uniprotkb:Q9VFF0 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110187|imex:IM-9552-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 intact-crc:01D233C06A8B2760|rigid:I/mySxcf8crPZjfRPEpQK578Rio false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8MRV7 uniprotkb:Q9VFF0 intact:EBI-2109296 intact:EBI-114079|uniprotkb:Q95U87|ensemblmetazoa:FBpp0082459|ensemblmetazoa:FBpp0082460 psi-mi:q8mrv7_drome(display_long)|uniprotkb:mRpL3(gene name)|psi-mi:mRpL3(display_short)|uniprotkb:CG8288(orf name) psi-mi:q9vff0_drome(display_long)|uniprotkb:CG3731(orf name)|uniprotkb:UQCR-C1(gene name)|psi-mi:UQCR-C1(display_short)|uniprotkb:CG 3731(gene name synonym)|uniprotkb:Dmel\CG3731(gene name synonym)|uniprotkb:MPPB(gene name synonym)|uniprotkb:Mpp(gene name synonym)|uniprotkb:UCR1(gene name synonym)|uniprotkb:Dmel_CG3731(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110192|imex:IM-9552-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0030686|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019927 refseq:NP_650401.1|refseq:NP_731954.1|flybase:FBgn0038271|ensemblmetazoa:FBgn0038271(gene)|ensemblmetazoa:FBtr0083000(transcript)|ensemblmetazoa:FBtr0083001(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-DME-611105|reactome:R-DME-8949664 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:1cLwoHe3+eYgQTDdI3SfOlIuoFs7227 rogid:z4g7+26pGtwjRXIxxayq7C1Zkqg7227 intact-crc:75657FDA2F74ABF5|rigid:aFCAjQeRmCBEsX9qBKLNqsVDXzk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VHB6 uniprotkb:Q8T4F2 intact:EBI-158722|ensemblmetazoa:FBpp0081591 intact:EBI-133471|uniprotkb:Q9VXX4|ensemblmetazoa:FBpp0073816|ensemblmetazoa:FBpp0311920 psi-mi:mtx1_drome(display_long)|uniprotkb:CG9393(orf name)|uniprotkb:Mitochondrial outer membrane import complex protein 1(gene name synonym) psi-mi:q8t4f2_drome(display_long)|uniprotkb:Dmel\CG5662(gene name)|psi-mi:Dmel\CG5662(display_short)|uniprotkb:Dmel_CG5662(orf name)|uniprotkb:CG5662(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110202|imex:IM-9552-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0037710(gene)|ensemblmetazoa:FBtr0082113(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070096"(mitochondrial outer membrane translocase complex assembly)|interpro:IPR017410(Metaxin)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|reactome:R-DME-9013404|refseq:NP_649908.1|flybase:FBgn0037710|dip:DIP-23833N flybase:FBgn0030620|refseq:NP_573009.1|refseq:NP_001285266.1|ensemblmetazoa:FBgn0030620(gene)|ensemblmetazoa:FBtr0073999(transcript)|ensemblmetazoa:FBtr0346086(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:T4aLLrLrYgcXH/P/2LMot+Ttcws7227 rogid:AHROgav+O6dHJS12r4C1zVsuZsQ7227 intact-crc:79A5CC5D3E9BAA19|rigid:dT6Splaea396r/dMPmwGbMwpOAE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P14318 uniprotkb:P82147 intact:EBI-138793|uniprotkb:A4UZF7|uniprotkb:Q1WWC7|uniprotkb:Q9V6M7|ensemblmetazoa:FBpp0086858 intact:EBI-206434|uniprotkb:Q8MLQ9|ensemblmetazoa:FBpp0072009|ensemblmetazoa:FBpp0307666 psi-mi:mp20_drome(display_long)|uniprotkb:Mp20(gene name)|psi-mi:Mp20(display_short)|uniprotkb:Tpn(gene name synonym)|uniprotkb:CG4696(orf name) psi-mi:l2efl_drome(display_long)|uniprotkb:"l(2)efl"(gene name)|psi-mi:"l(2)efl"(display_short)|uniprotkb:CG4533(orf name)|uniprotkb:Protein Efl21(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110197|imex:IM-9552-526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476643.1|flybase:FBgn0002789|refseq:NP_001014522.2|dip:DIP-18096N|go:"GO:0005737"(cytoplasm)|go:"GO:0007520"(myoblast fusion)|go:"GO:1901739"(regulation of myoblast fusion)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|ensemblmetazoa:FBtr0087745(transcript)|interpro:IPR036872|ensemblmetazoa:FBgn0002789(gene) refseq:NP_523827.1|flybase:FBgn0011296|refseq:NP_001261156.1|dip:DIP-18793N|ensemblmetazoa:FBgn0011296(gene)|ensemblmetazoa:FBtr0072100(transcript)|ensemblmetazoa:FBtr0336685(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0030018"(Z disc)|go:"GO:0042026"(protein refolding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:91HEOu72QM/VxbqiDXCT+Cul8f47227 rogid:AIIe6XF3BthWgusp/c7gWDTBjgM7227 intact-crc:95A21B4BE8BD832E|rigid:e95TZtdc/65R7HeR4QgAsduhVCo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8MLV5 uniprotkb:Q8T0S7 intact:EBI-2110210|ensemblmetazoa:FBpp0071583 intact:EBI-870039 psi-mi:q8mlv5_drome(display_long)|uniprotkb:NC2alpha(gene name)|psi-mi:NC2alpha(display_short)|uniprotkb:NC2-alpha(gene name synonym)|uniprotkb:CG10318(orf name) psi-mi:q8t0s7_drome(display_long)|uniprotkb:Unc-76(gene name)|psi-mi:Unc-76(display_short)|uniprotkb:CG3981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110207|imex:IM-9552-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0034650|ensemblmetazoa:FBgn0034650(gene)|ensemblmetazoa:FBtr0071666(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027116 flybase:FBgn0040395|go:"GO:0005737"(cytoplasm)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:vlRjon7NZckXqH20PwVG1Qk/ezU7227 rogid:L008dmKy3XlWdkOuYVhnL7N0uXg7227 intact-crc:2809824FB3F013B3|rigid:ystS+OxCEfzinpdr9ha7NWnSOn4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) intact:EBI-2108411 uniprotkb:Q9V3T1 - intact:EBI-169390|ensemblmetazoa:FBpp0070165 psi-mi:q8img7_drome(display_short)|psi-mi:EBI-2108411(display_long)|uniprotkb:Dmel_CG11525(orf name)|uniprotkb:CycG(gene name)|psi-mi:CycG(display_short)|uniprotkb:CG11525(orf name) psi-mi:q9v3t1_drome(display_long)|uniprotkb:mus81(gene name)|psi-mi:mus81(display_short)|uniprotkb:"EG:BACR7A4.16"(gene name synonym)|uniprotkb:Dmel\CG3026(gene name synonym)|uniprotkb:Mus81(gene name synonym)|uniprotkb:Dmel_CG3026(orf name)|uniprotkb:CG3026(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110226|imex:IM-9552-528 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IMG7(uniprot-removed-ac) ensemblmetazoa:FBgn0040347(gene)|ensemblmetazoa:FBtr0070170(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0048257"(3'-flap endonuclease activity)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027421|interpro:IPR042530|reactome:R-DME-5693568|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|refseq:NP_569873.1|flybase:FBgn0040347 psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GwDM/XQ/mtqkftw2t9BwmojZmFA7227 rogid:dfhXcS0xUa4+4ewimRcveZJ+cwY7227 intact-crc:404B258FC27A5BE7|rigid:cRlLKDIyHY0PC5WCdEScwPLHvpA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q0E924 uniprotkb:Q9V7Y2 intact:EBI-498791|uniprotkb:Q9V8N2|ensemblmetazoa:FBpp0085796|ensemblmetazoa:FBpp0085797|ensemblmetazoa:FBpp0085798|ensemblmetazoa:FBpp0111776 intact:EBI-2110219|uniprotkb:Q0E946|ensemblmetazoa:FBpp0086158|ensemblmetazoa:FBpp0086159 psi-mi:q0e924_drome(display_long)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:"l(2)03709"(gene name synonym)|uniprotkb:Dmel\CG15081(gene name synonym)|uniprotkb:anon-WO0118547.157(gene name synonym)|uniprotkb:anon-WO02079478.4(gene name synonym)|uniprotkb:"l (2) 03709"(gene name synonym)|uniprotkb:phb2(gene name synonym)|uniprotkb:CG15081(orf name)|uniprotkb:Dmel_CG15081(orf name) psi-mi:sgpl_drome(display_long)|uniprotkb:Spl(gene name synonym)|uniprotkb:Sply(gene name)|psi-mi:Sply(display_short)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:CG8946(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110216|imex:IM-9552-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097373.1|refseq:NP_652030.3|refseq:NP_725831.2|refseq:NP_725832.2|flybase:FBgn0010551|ensemblmetazoa:FBgn0010551(gene)|ensemblmetazoa:FBtr0086614(transcript)|ensemblmetazoa:FBtr0086615(transcript)|ensemblmetazoa:FBtr0086616(transcript)|ensemblmetazoa:FBtr0112863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 refseq:NP_652032.1|refseq:NP_725652.1|flybase:FBgn0010591|ensemblmetazoa:FBgn0010591(gene)|ensemblmetazoa:FBtr0087007(transcript)|ensemblmetazoa:FBtr0087008(transcript)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-DME-1660661 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:E9XsMFEjQ/t0K3ezYW4NjvPb9pc7227 rogid:o1Jko4T4gY2Ue9/zOUjafuqyWkw7227 intact-crc:2F6C8994A14EF387|rigid:mDhe+pwaB01Y1ajNpX6r1igoSic false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q27884 uniprotkb:O77430 intact:EBI-99228|uniprotkb:Q5BIJ4|uniprotkb:Q8MRZ7|uniprotkb:Q9W3Z8|ensemblmetazoa:FBpp0070883|ensemblmetazoa:FBpp0303847|ensemblmetazoa:FBpp0303848|ensemblmetazoa:FBpp0303849 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:ppp6_drome(display_long)|uniprotkb:PpV(gene name)|psi-mi:PpV(display_short)|uniprotkb:PPPV6A(gene name synonym)|uniprotkb:CG12217(orf name)|uniprotkb:Phosphatase V(gene name synonym) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110236|imex:IM-9552-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511061.1|flybase:FBgn0003139|refseq:NP_001259272.1|refseq:NP_001259273.1|refseq:NP_001259274.1|ensemblmetazoa:FBgn0003139(gene)|ensemblmetazoa:FBtr0070921(transcript)|ensemblmetazoa:FBtr0331430(transcript)|ensemblmetazoa:FBtr0331431(transcript)|ensemblmetazoa:FBtr0331432(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|dip:DIP-20494N refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:EO7pNWevzqdO1j5I6OVUdRjjWCs7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 intact-crc:08072EF471D5E8DA|rigid:LIjXCGlRcv4Wg4PL4qUv6+QEcRA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P54399 uniprotkb:P31409 intact:EBI-123796|uniprotkb:Q9VUL7|uniprotkb:Q53YH5|uniprotkb:Q86PE2|uniprotkb:Q8IQL8|ensemblmetazoa:FBpp0075401|ensemblmetazoa:FBpp0312224 intact:EBI-198835|uniprotkb:Q53YH8|uniprotkb:Q9VG52|ensemblmetazoa:FBpp0082139|ensemblmetazoa:FBpp0082140|ensemblmetazoa:FBpp0290875 psi-mi:pdi_drome(display_long)|uniprotkb:Pdi(gene name)|psi-mi:Pdi(display_short)|uniprotkb:CG6988(orf name) psi-mi:vatb_drome(display_long)|uniprotkb:Vha55(gene name)|psi-mi:Vha55(display_short)|uniprotkb:CG17369(orf name)|uniprotkb:Vacuolar proton pump subunit B(gene name synonym)|uniprotkb:V-ATPase 55 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110231|imex:IM-9552-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524079.1|refseq:NP_001287070.1|ensemblmetazoa:FBgn0286818(gene)|ensemblmetazoa:FBtr0075648(transcript)|ensemblmetazoa:FBtr0346644(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045169"(fusome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-DME-381426|reactome:R-DME-5358346|reactome:R-DME-8957275|dip:DIP-21766N|flybase:FBgn0286818 refseq:NP_001163597.1|refseq:NP_476908.1|refseq:NP_731726.1|flybase:FBgn0005671|dip:DIP-17495N|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016787"(hydrolase activity)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|ensemblmetazoa:FBgn0005671(gene)|ensemblmetazoa:FBtr0082670(transcript)|ensemblmetazoa:FBtr0082671(transcript)|ensemblmetazoa:FBtr0301661(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:5WvkcBmjcDkzw5HGvxX9J30oLL47227 rogid:KBtajc3ZD825Z5cbJUt8QmsEdBo7227 intact-crc:C104A1BA2A889371|rigid:Zd/6oSLNQZVq7FIkar72qbyQAOc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24547 uniprotkb:P18489 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-497912|uniprotkb:Q8MKX1|uniprotkb:Q9V5I6|uniprotkb:Q3HKB4|uniprotkb:B7YZD5|uniprotkb:B7YZD6|ensemblmetazoa:FBpp0271782 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:syb_drome(display_long)|uniprotkb:Syb(gene name)|psi-mi:Syb(display_short)|uniprotkb:CG12210(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110251|imex:IM-9552-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_001286278.1|refseq:NP_001137633.1|refseq:NP_001137634.1|refseq:NP_523680.1|refseq:NP_724906.1|flybase:FBgn0003660|ensemblmetazoa:FBgn0003660(gene)|ensemblmetazoa:FBtr0273274(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0043005"(neuron projection)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-6811440|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-888590|reactome:R-DME-8980692|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013405|reactome:R-DME-9013406|reactome:R-DME-9013407|reactome:R-DME-9035034|reactome:R-DME-9609523 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:0GVct78wgjr8E88ZYPr03wY7yr87227 intact-crc:D90DF2E5F8ED09D1|rigid:e0x0A3/0WRdLYdD3ESw9B7y+8XQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q03017-1 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-200614|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q03017-1(display_long)|uniprotkb:Maternal/zygotic(isoform synonym)|uniprotkb:B(isoform synonym)|uniprotkb:D(isoform synonym)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)|uniprotkb:CG5848(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110246|imex:IM-9552-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 intact:EBI-200600(cact_drome)|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227 intact-crc:13C971A569B8EB5C|rigid:V18yvh/IXYov676W4GfPXD060nw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q8IGU5 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-466654|ensemblmetazoa:FBpp0084796 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q8igu5_drome(display_long)|uniprotkb:FipoQ(gene name)|psi-mi:FipoQ(display_short)|uniprotkb:CG2010(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110241|imex:IM-9552-530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 flybase:FBgn0039667|ensemblmetazoa:FBgn0039667(gene)|ensemblmetazoa:FBtr0085428(transcript)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|interpro:IPR039940 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:08sGTujKzT1RyNWeTykmgp+dN4E7227 intact-crc:1C7AEE9AB704EB5C|rigid:JhaqG2N6zJnt69hAeEhIop+2m4Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q23983 uniprotkb:Q24547 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110256|imex:IM-9552-532 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 intact-crc:3B3B32BA00C2F0C3|rigid:oYwyOJI+zGbuT2Owm9puk6noEj0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95SY7 uniprotkb:A5XCL5 intact:EBI-2110264|ensemblmetazoa:FBpp0083606 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 psi-mi:q95sy7_drome(display_long)|uniprotkb:Sar1(gene name)|psi-mi:Sar1(display_short)|uniprotkb:sar1(gene name synonym)|uniprotkb:CG7073(orf name) psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110261|imex:IM-9552-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0038947|ensemblmetazoa:FBgn0038947(gene)|ensemblmetazoa:FBtr0084208(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008363"(larval chitin-based cuticle development)|go:"GO:0009306"(protein secretion)|go:"GO:0016050"(vesicle organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048081"(positive regulation of cuticle pigmentation)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR006687(GTP-binding protein SAR1)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417 refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:1eF4q8+qt6vmsieEMxqyfJoqKtM7227 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 intact-crc:6D28A4CCDCF6DCEA|rigid:r/5JK2xmRlYAkZ9cv1de3mt+AuE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFV9 uniprotkb:O61650 intact:EBI-121507|ensemblmetazoa:FBpp0082219|ensemblmetazoa:FBpp0082220|ensemblmetazoa:FBpp0082221|ensemblmetazoa:FBpp0082222|ensemblmetazoa:FBpp0082223 intact:EBI-2110274 psi-mi:q9vfv9_drome(display_long)|uniprotkb:Droj2(gene name)|psi-mi:Droj2(display_short)|uniprotkb:CG8863(orf name)|uniprotkb:DnaJL2A(gene name synonym)|uniprotkb:anon-WO0118547.404(gene name synonym)|uniprotkb:Dmel_CG8863(orf name)|uniprotkb:DROJ2(gene name synonym)|uniprotkb:Dmel\CG8863(gene name synonym)|uniprotkb:Hsp40(gene name synonym) psi-mi:o61650_drome(display_long)|uniprotkb:Stip1(gene name)|psi-mi:Stip1(display_short)|uniprotkb:Hop(gene name synonym)|uniprotkb:CG2720(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110271|imex:IM-9552-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650283.1|refseq:NP_731804.1|refseq:NP_731805.1|refseq:NP_731806.1|refseq:NP_731807.1|flybase:FBgn0038145|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|ensemblmetazoa:FBgn0038145(gene)|reactome:R-DME-3371497|ensemblmetazoa:FBtr0082751(transcript)|ensemblmetazoa:FBtr0082752(transcript)|ensemblmetazoa:FBtr0082753(transcript)|ensemblmetazoa:FBtr0082754(transcript)|ensemblmetazoa:FBtr0082755(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding) flybase:FBgn0024352|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:2SIHKEbZ/eKMfB2gLDRtjBat+V47227 rogid:qnybcdQVZlzRIKcz9C7le5ICDig7227 intact-crc:3333DD9A7D1E6518|rigid:nii3+hcgZXkz7a1gX9+F2Ivfgdo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31007 uniprotkb:P46150 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-206130|uniprotkb:P91930|uniprotkb:Q24053|uniprotkb:Q24435|uniprotkb:Q9W3B4|uniprotkb:A4V458|uniprotkb:Q7KVS6|uniprotkb:Q7KVS7|uniprotkb:Q9W3B5|uniprotkb:Q9W3B6|uniprotkb:Q9W3B7|ensemblmetazoa:FBpp0089236|ensemblmetazoa:FBpp0300514 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:moeh_drome(display_long)|uniprotkb:Moe(gene name)|psi-mi:Moe(display_short)|uniprotkb:EMR1(gene name synonym)|uniprotkb:CG10701(orf name)|uniprotkb:Moesin(gene name synonym)|uniprotkb:Protein D17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110295|imex:IM-9552-536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N refseq:NP_001245584.1|refseq:NP_525082.2|refseq:NP_727290.1|refseq:NP_727291.1|refseq:NP_727292.1|refseq:NP_996387.1|refseq:NP_996388.1|refseq:NP_996389.1|refseq:NP_996390.1|refseq:NP_996391.1|refseq:NP_996392.1|flybase:FBgn0011661|dip:DIP-52150N|ensemblmetazoa:FBgn0011661(gene)|ensemblmetazoa:FBtr0071278(transcript)|ensemblmetazoa:FBtr0308194(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016057"(regulation of membrane potential in photoreceptor cell)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035003"(subapical complex)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035327"|go:"GO:0042052"(rhabdomere development)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045313"(rhabdomere membrane biogenesis)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|reactome:R-DME-373752 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:SOC9aiyQCcmj5WK8Qr3obv9rxz87227 intact-crc:E67E4BEC16230792|rigid:IypHJ457/mS6snAYDh0LWhwMf/s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W2M2-1 uniprotkb:Q9VRJ4 intact:EBI-261103|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 intact:EBI-2109495|ensemblmetazoa:FBpp0076882 psi-mi:q9w2m2-1(display_long)|uniprotkb:F(isoform synonym)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym)|uniprotkb:CG9364(orf name) psi-mi:q9vrj4_drome(display_long)|uniprotkb:Dhrs4(gene name)|psi-mi:Dhrs4(display_short)|uniprotkb:DHRS4(gene name synonym)|uniprotkb:Dmel\CG10672(gene name synonym)|uniprotkb:CG10672(orf name)|uniprotkb:Dmel_CG10672(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110285|imex:IM-9552-534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-261090(trea_drome)|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript) refseq:NP_647946.1|flybase:FBgn0035588|ensemblmetazoa:FBgn0035588(gene)|ensemblmetazoa:FBtr0077179(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005777"(peroxisome)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-DME-5365859|reactome:R-DME-9033241 psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 rogid:JIo6DRNtCgSazMU6uqd7EWTsWNM7227 intact-crc:A45AA147183B7F14|rigid:JYuj/WDbDLPjE9elYHiC4lH6R5Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31007 uniprotkb:Q8WS23 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-870047 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:q8ws23_drome(display_long)|uniprotkb:rols(gene name)|psi-mi:rols(display_short)|uniprotkb:rols6(gene name synonym)|uniprotkb:CG32096(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110290|imex:IM-9552-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N flybase:FBgn0041096|go:"GO:0005737"(cytoplasm)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016740"(transferase activity)|go:"GO:0030018"(Z disc)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:liZ6VBX2yzld6LPOkXv5Ro19rKY7227 intact-crc:F91384BF9C99C4E4|rigid:Um8QoPK6MQiHK65Ec2yL5XhxWII false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:P18053 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110280|imex:IM-9552-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 intact-crc:7AAC73589875C595|rigid:XvopFFNF4GMNqqsx7tazvkm0l2A false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W2M2-1 uniprotkb:A5XCL5 intact:EBI-261103|ensemblmetazoa:FBpp0071468|ensemblmetazoa:FBpp0071469 intact:EBI-2109280|ensemblmetazoa:FBpp0290912 psi-mi:q9w2m2-1(display_long)|uniprotkb:F(isoform synonym)|uniprotkb:Treh(gene name)|psi-mi:Treh(display_short)|uniprotkb:Alpha,alpha-trehalase(gene name synonym)|uniprotkb:Alpha,alpha-trehalose glucohydrolase(gene name synonym)|uniprotkb:CG9364(orf name) psi-mi:a5xcl5_drome(display_long)|uniprotkb:UGP(gene name)|psi-mi:UGP(display_short)|uniprotkb:UGP-RD(gene name synonym)|uniprotkb:Dmel\CG4347(gene name synonym)|uniprotkb:UDPGPP(gene name synonym)|uniprotkb:UGPase(gene name synonym)|uniprotkb:dUGP(gene name synonym)|uniprotkb:CG4347(orf name)|uniprotkb:Dmel_CG4347(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110305|imex:IM-9552-538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-261090(trea_drome)|ensemblmetazoa:FBgn0003748(gene)|ensemblmetazoa:FBtr0071539(transcript)|ensemblmetazoa:FBtr0071540(transcript) refseq:NP_001163399.1|flybase:FBgn0035978|ensemblmetazoa:FBgn0035978(gene)|ensemblmetazoa:FBtr0301698(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044 psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:piEVj2O+8v2yFdBCY27irTizhVo7227 rogid:bpQHHfYhPCKAoeLlxJfnHYKcOhs7227 intact-crc:5DB99A65947DF156|rigid:SjFaDcf/xxFqFUXh8g60sn9X2Fg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFE3 uniprotkb:P23380 intact:EBI-160737|ensemblmetazoa:FBpp0082464|ensemblmetazoa:FBpp0300391 intact:EBI-185634|uniprotkb:A4UZ55|uniprotkb:Q0E9N6|uniprotkb:Q53XD4|uniprotkb:Q9V9D2|intact:EBI-3405892|ensemblmetazoa:FBpp0085483|ensemblmetazoa:FBpp0085484|ensemblmetazoa:FBpp0085485|ensemblmetazoa:FBpp0085486 psi-mi:q9vfe3_drome(display_long)|uniprotkb:VhaPPA1-1(gene name)|psi-mi:VhaPPA1-1(display_short)|uniprotkb:Dmel\CG7007(gene name synonym)|uniprotkb:V0c''(gene name synonym)|uniprotkb:Vha26(gene name synonym)|uniprotkb:VhaPPA1(gene name synonym)|uniprotkb:vhaPPA1-1(gene name synonym)|uniprotkb:Dmel_CG7007(orf name)|uniprotkb:CG7007(orf name) psi-mi:vatl_drome(display_long)|uniprotkb:Vha16-1(gene name)|psi-mi:Vha16-1(display_short)|uniprotkb:VHA(gene name synonym)|uniprotkb:CG3161(orf name)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)|uniprotkb:Ductin(gene name synonym)|uniprotkb:Vha16(gene name synonym)|uniprotkb:Vacuolar H+ ATPase subunit 16-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110300|imex:IM-9552-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652010.1|flybase:FBgn0028662|ensemblmetazoa:FBgn0028662(gene)|ensemblmetazoa:FBtr0083005(transcript)|ensemblmetazoa:FBtr0308030(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|refseq:NP_001247111.1 refseq:NP_476801.1|refseq:NP_724474.1|refseq:NP_724475.1|refseq:NP_724476.1|flybase:FBgn0262736|dip:DIP-19390N|ensemblmetazoa:FBgn0262736(gene)|ensemblmetazoa:FBtr0086150(transcript)|ensemblmetazoa:FBtr0086151(transcript)|ensemblmetazoa:FBtr0086152(transcript)|ensemblmetazoa:FBtr0086153(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0033227"(dsRNA transport)|go:"GO:0045169"(fusome)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|reactome:R-DME-1222556|reactome:R-DME-6798695|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ehVJ3KtyJ98C/cC0Q1GePGBi9eU7227 rogid:uxgicWAlJCbsWVC4WNdmaEtY1Ck7227 intact-crc:3A623B5CC9D33C30|rigid:WdPM4IutFSjxANeMFvURIMJGugE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VLS4 uniprotkb:Q9VPR1 intact:EBI-184851|ensemblmetazoa:FBpp0079256|ensemblmetazoa:FBpp0312113 intact:EBI-2110318|ensemblmetazoa:FBpp0077726 psi-mi:q9vls4_drome(display_long)|uniprotkb:Acbp1(gene name)|psi-mi:Acbp1(display_short)|uniprotkb:Dmel\CG8498(gene name synonym)|uniprotkb:CG8498(orf name)|uniprotkb:Dmel_CG8498(orf name)|uniprotkb:DmCG8498(gene name synonym) psi-mi:q9vpr1_drome(display_long)|uniprotkb:CG2789(orf name)|uniprotkb:Tspo(gene name)|psi-mi:Tspo(display_short)|uniprotkb:Dmel\CG2789(gene name synonym)|uniprotkb:"anon-EST:Posey116"(gene name synonym)|uniprotkb:dTSPO(gene name synonym)|uniprotkb:tspo(gene name synonym)|uniprotkb:Dmel_CG2789(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110315|imex:IM-9552-540 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609187.1|flybase:FBgn0031992|refseq:NP_001285744.1|ensemblmetazoa:FBgn0031992(gene)|ensemblmetazoa:FBtr0079640(transcript)|ensemblmetazoa:FBtr0346463(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|reactome:R-DME-77289 refseq:NP_608531.1|flybase:FBgn0031263|ensemblmetazoa:FBgn0031263(gene)|ensemblmetazoa:FBtr0078066(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR004307(TspO/MBR-related protein)|interpro:IPR038330 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:FurG7a1eq1sv+1OVX6euC/qRoxI7227 rogid:pQs4JgYL54YWWDNpiBnWyFO3puU7227 intact-crc:DFD03EB6A7C42380|rigid:9omDPVXRh3Zbk+x6d8reo+RwXNA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7JZN0 uniprotkb:Q9U1L3 intact:EBI-92490|intact:EBI-2109559|ensemblmetazoa:FBpp0086627 intact:EBI-2109555 psi-mi:q7jzn0_drome(display_long)|uniprotkb:Sec61beta(gene name)|psi-mi:Sec61beta(display_short)|uniprotkb:sec61beta(gene name synonym)|uniprotkb:Sec61-beta(gene name synonym)|uniprotkb:Sec61beta-RA(gene name synonym)|uniprotkb:Dmel_CG10130(orf name)|uniprotkb:CG10130(orf name)|uniprotkb:DSec61beta(gene name synonym)|uniprotkb:Dmel\CG10130(gene name synonym)|uniprotkb:Sec1(gene name synonym)|uniprotkb:Sec61(gene name synonym)|uniprotkb:Secbeta61(gene name synonym)|uniprotkb:dSec61beta(gene name synonym)|uniprotkb:"l(2)07214"(gene name synonym)|uniprotkb:sec61b(gene name synonym) psi-mi:q9u1l3_drome(display_long)|uniprotkb:"EG:BACR7A4.5"(gene name synonym)|uniprotkb:CG11642(orf name)|uniprotkb:TRAM(gene name)|psi-mi:TRAM(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110310|imex:IM-9552-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652037.1|flybase:FBgn0010638|ensemblmetazoa:FBgn0010638(gene)|ensemblmetazoa:FBtr0087498(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|reactome:R-DME-9609523 flybase:FBgn0040340|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016447(Translocation associated membrane protein) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of combined evidence predictions (JY) 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:RzxFF9bAFufAgJ6A8aA7ZD7BVd87227 rogid:epGYqkmeES/ubQXA+FJsweSYEsA7227 intact-crc:7AF4E16CB9FD24CB|rigid:6vs8Etd0d1m1lXrB2H7OnUuHaz8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:O77430 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110323|imex:IM-9552-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 intact-crc:7CB7E048F02110EA|rigid:8DKjS+XupQVlV5eUKnBN8EcWXlU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTQ9 uniprotkb:Q7KKI9 intact:EBI-145364|ensemblmetazoa:FBpp0075772|ensemblmetazoa:FBpp0312163 intact:EBI-2109596|ensemblmetazoa:FBpp0080013 psi-mi:q9vtq9_drome(display_long)|uniprotkb:DmCG7257(gene name synonym)|uniprotkb:Dm_Rpt4c(gene name synonym)|uniprotkb:Dmel\CG7257(gene name synonym)|uniprotkb:Dmel_CG7257(orf name)|uniprotkb:7257(gene name synonym)|uniprotkb:Rpt4R(gene name)|psi-mi:Rpt4R(display_short)|uniprotkb:CG7257(orf name) psi-mi:q7kki9_drome(display_long)|uniprotkb:Pk34A(gene name)|psi-mi:Pk34A(display_short)|uniprotkb:CG5182(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110337|imex:IM-9552-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648525.1|flybase:FBgn0036224|refseq:NP_001287039.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|ensemblmetazoa:FBtr0346545(transcript)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|ensemblmetazoa:FBgn0036224(gene)|ensemblmetazoa:FBtr0076040(transcript) flybase:FBgn0028410|ensemblmetazoa:FBgn0028410(gene)|ensemblmetazoa:FBtr0080432(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:qKddY9ayACDKkIZPibAZTgXAvJE7227 rogid:vHS7jWE9k2Z/WZU3fKejxK5ISVc7227 intact-crc:9FE21BC6FB5E0185|rigid:ACGagd1GwyTsVTVEnCx1GtF+CAs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97121 uniprotkb:Q7K0S9 intact:EBI-2108466 intact:EBI-187683|intact:EBI-2110328|ensemblmetazoa:FBpp0086902 psi-mi:o97121_drome(display_long)|uniprotkb:CG5345(orf name)|uniprotkb:Eip40(gene name synonym)|uniprotkb:Eip55E(gene name)|psi-mi:Eip55E(display_short) psi-mi:glis2_drome(display_long)|uniprotkb:sug(gene name)|psi-mi:sug(display_short)|uniprotkb:CG3850(orf name)|uniprotkb:Protein sugarbabe(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110332|imex:IM-9552-542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000566|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0004123"(cystathionine gamma-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019346"(transsulfuration)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0044540"("L-cystine L-cysteine-lyase (deaminating)")|go:"GO:0080146"(L-cysteine desulfhydrase activity)|interpro:IPR000277(Cys/Met metabolism, pyridoxal phosphate-dependent enzyme)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region) refseq:NP_610826.1|flybase:FBgn0033782|ensemblmetazoa:FBgn0033782(gene)|ensemblmetazoa:FBtr0087789(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0016607"(nuclear speck)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LmlDNqGOA7CxKbDlVFTNfpzlc2k7227 rogid:mfPXbvpyKOAyAMoggnAa4V9JvqY7227 intact-crc:D8576E28F2460A37|rigid:t0Hz+QfX8Ejqk8MNeqL1B9JkxPk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95SU8 uniprotkb:Q9NIU5 intact:EBI-2110347 intact:EBI-2110342|ensemblmetazoa:FBpp0079472 psi-mi:q95su8_drome(display_long)|uniprotkb:CG3066(orf name)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short) psi-mi:q9niu5_drome(display_long)|uniprotkb:CG4600(orf name)|uniprotkb:yip2(gene name)|psi-mi:yip2(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110351|imex:IM-9552-544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0037515|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|interpro:IPR022700|interpro:IPR038565 flybase:FBgn0040064|ensemblmetazoa:FBgn0040064(gene)|ensemblmetazoa:FBtr0079876(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006635"(fatty acid beta-oxidation)|interpro:IPR016039(Thiolase-like)|interpro:IPR020616 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:V+2OZLJlOarK8Loq3oe+4kkCdQ07227 rogid:nHevw00DLS89IYdE/l3zL9IgFKQ7227 intact-crc:4103C9532097BE11|rigid:VkwDnNxNA8TMWAIukBcZNbNFkaE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VP62 uniprotkb:Q7KTP4 intact:EBI-171102|ensemblmetazoa:FBpp0078069 intact:EBI-2110356|ensemblmetazoa:FBpp0078675|ensemblmetazoa:FBpp0078676|ensemblmetazoa:FBpp0290754|ensemblmetazoa:FBpp0290755 psi-mi:q9vp62_drome(display_long)|uniprotkb:Dmel\CG9389(gene name)|psi-mi:Dmel\CG9389(display_short)|uniprotkb:142336_at(gene name synonym)|uniprotkb:IMP(gene name synonym)|uniprotkb:CG9389(orf name)|uniprotkb:Dmel_CG9389(orf name) psi-mi:q7ktp4_drome(display_long)|uniprotkb:CG33113(orf name)|uniprotkb:Rtnl1(gene name)|psi-mi:Rtnl1(display_short)|uniprotkb:CG18623(gene name synonym)|uniprotkb:CG8895(gene name synonym)|uniprotkb:142893_at(gene name synonym)|uniprotkb:Dmel\CG33113(gene name synonym)|uniprotkb:G9(gene name synonym)|uniprotkb:Retl1(gene name synonym)|uniprotkb:Rtn1(gene name synonym)|uniprotkb:Rtnl-1(gene name synonym)|uniprotkb:rtnl1(gene name synonym)|uniprotkb:Dmel_CG33113(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110361|imex:IM-9552-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649295.1|flybase:FBgn0037064|ensemblmetazoa:FBgn0037064(gene)|ensemblmetazoa:FBtr0078415(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|reactome:R-DME-1855183 refseq:NP_001162876.1|refseq:NP_001162877.1|refseq:NP_787984.1|refseq:NP_787985.1|flybase:FBgn0053113|ensemblmetazoa:FBgn0053113(gene)|ensemblmetazoa:FBtr0079039(transcript)|ensemblmetazoa:FBtr0079040(transcript)|ensemblmetazoa:FBtr0301539(transcript)|ensemblmetazoa:FBtr0301540(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0045169"(fusome)|interpro:IPR003388(Reticulon) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:8boAZiukAfFJvhE/Kbm2sydVhi07227 rogid:Q+wDuLe4s1Us757eYcRN+vtm2Mk7227 intact-crc:F57473760142275D|rigid:oe6GwyewYCnPWoic9VhJTGQeeqw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97418 uniprotkb:Q8SWX9 intact:EBI-128347|ensemblmetazoa:FBpp0070370|ensemblmetazoa:FBpp0309795 intact:EBI-2110366|ensemblmetazoa:FBpp0084605 psi-mi:o97418_drome(display_long)|uniprotkb:ND-B14.5A(gene name)|psi-mi:ND-B14.5A(display_short)|uniprotkb:CG3621-RA(gene name synonym)|uniprotkb:"EG:152A3.7"(gene name synonym)|uniprotkb:152A3.7(gene name synonym)|uniprotkb:"BcDNA:RE75088"(gene name synonym)|uniprotkb:Dmel\CG3621(gene name synonym)|uniprotkb:N4AM(gene name synonym)|uniprotkb:RNAA(gene name synonym)|uniprotkb:anon-2D(gene name synonym)|uniprotkb:anon-2Db(gene name synonym)|uniprotkb:Dmel_CG3621(orf name)|uniprotkb:CG3621(orf name)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym) psi-mi:q8swx9_drome(display_long)|uniprotkb:CROT(gene name)|psi-mi:CROT(display_short)|uniprotkb:CG12428(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110369|imex:IM-9552-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569984.2|flybase:FBgn0025839|refseq:NP_001284805.1|ensemblmetazoa:FBgn0025839(gene)|ensemblmetazoa:FBtr0070386(transcript)|ensemblmetazoa:FBtr0343049(transcript)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|reactome:R-DME-611105|reactome:R-DME-6799198 flybase:FBgn0039543|ensemblmetazoa:FBgn0039543(gene)|ensemblmetazoa:FBtr0085236(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:w3o67xPTnqaowZBtC90RHq/nxYY7227 rogid:GB95ia4DU4Pk6uP6oeldtx4hyvA7227 intact-crc:FD040E0473354027|rigid:zvEDASQ6CK9o8W0wnUndpme+nh8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VBW6 uniprotkb:P82147 intact:EBI-121952|intact:EBI-1627924|uniprotkb:Q960P9|ensemblmetazoa:FBpp0084178|ensemblmetazoa:FBpp0303321 intact:EBI-206434|uniprotkb:Q8MLQ9|ensemblmetazoa:FBpp0072009|ensemblmetazoa:FBpp0307666 psi-mi:dan_drome(display_long)|uniprotkb:dan(gene name)|psi-mi:dan(display_short)|uniprotkb:CG11849(orf name) psi-mi:l2efl_drome(display_long)|uniprotkb:"l(2)efl"(gene name)|psi-mi:"l(2)efl"(display_short)|uniprotkb:CG4533(orf name)|uniprotkb:Protein Efl21(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110384|imex:IM-9552-546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0039286(gene)|ensemblmetazoa:FBtr0084803(transcript)|ensemblmetazoa:FBtr0330289(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007469"(antennal development)|go:"GO:0021556"(central nervous system formation)|go:"GO:0048749"(compound eye development)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR036388|rcsb pdb:2ELH|refseq:NP_651346.1|flybase:FBgn0039286|refseq:NP_001262949.1 refseq:NP_523827.1|flybase:FBgn0011296|refseq:NP_001261156.1|dip:DIP-18793N|ensemblmetazoa:FBgn0011296(gene)|ensemblmetazoa:FBtr0072100(transcript)|ensemblmetazoa:FBtr0336685(transcript)|go:"GO:0009408"(response to heat)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0030018"(Z disc)|go:"GO:0042026"(protein refolding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:T26et6XKNnh3AcOgCyYsNj7CpgU7227 rogid:AIIe6XF3BthWgusp/c7gWDTBjgM7227 intact-crc:F33B5626D1BBF761|rigid:6bHa2liKfD7+uO/Dz9QDvgpN9dk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VD05 uniprotkb:O97471 intact:EBI-104112|intact:EBI-1630345|ensemblmetazoa:FBpp0111520 intact:EBI-2110377 psi-mi:q9vd05_drome(display_long)|uniprotkb:CG13851(gene name)|psi-mi:CG13851(display_short)|uniprotkb:CG13845(gene name synonym)|uniprotkb:CG13846(gene name synonym)|uniprotkb:Dmel\CG34376(gene name synonym)|uniprotkb:CG31160(orf name)|uniprotkb:CG34376(orf name)|uniprotkb:Dmel_CG34376(orf name) psi-mi:o97471_drome(display_long)|uniprotkb:CG1742(orf name)|uniprotkb:Mgstl(gene name)|psi-mi:Mgstl(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110374|imex:IM-9552-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732741.1|flybase:FBgn0085405|ensemblmetazoa:FBgn0085405(gene)|ensemblmetazoa:FBtr0112608(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007588(Zinc finger, FLYWCH-type)|interpro:IPR011333(BTB/POZ fold)|dip:DIP-17133N flybase:FBgn0025814|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)")|interpro:IPR023352|interpro:IPR040162 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6yqX459cRLT5e+TnNpj1qorFmkk7227 rogid:Ar/i60IzjP3Bv0eOWpzQf8WuVGU7227 intact-crc:76F123995A795118|rigid:zP5rKDiTwCqQb9+3h03ftrWLZIM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VI08 uniprotkb:Q9VB23 intact:EBI-89535|ensemblmetazoa:FBpp0081207 intact:EBI-103072|uniprotkb:Q9Y0Y1|ensemblmetazoa:FBpp0084573|ensemblmetazoa:FBpp0084574|ensemblmetazoa:FBpp0084575|ensemblmetazoa:FBpp0084577|ensemblmetazoa:FBpp0084578|ensemblmetazoa:FBpp0084579 psi-mi:q9vi08_drome(display_long)|uniprotkb:"BcDNA:GH28351"(gene name)|psi-mi:"BcDNA:GH28351"(display_short)|uniprotkb:Dmel\CG10298(gene name synonym)|uniprotkb:CG10298(orf name)|uniprotkb:Dmel_CG10298(orf name) psi-mi:q9vb23_drome(display_long)|uniprotkb:wdb(gene name)|psi-mi:wdb(display_short)|uniprotkb:BcDNA.LD34343(gene name synonym)|uniprotkb:0318(gene name synonym)|uniprotkb:07(gene name synonym)|uniprotkb:B56-2(gene name synonym)|uniprotkb:"BEST:LD02456"(gene name synonym)|uniprotkb:"BcDNA:LD34343"(gene name synonym)|uniprotkb:Dmel\CG5643(gene name synonym)|uniprotkb:EP3559(gene name synonym)|uniprotkb:LD02456(gene name synonym)|uniprotkb:PP2-AB(gene name synonym)|uniprotkb:PP2A(gene name synonym)|uniprotkb:PP2A-B'(gene name synonym)|uniprotkb:PP2A[B'-2](gene name synonym)|uniprotkb:PP2a(gene name synonym)|uniprotkb:WDB(gene name synonym)|uniprotkb:Wdb(gene name synonym)|uniprotkb:dB56-2(gene name synonym)|uniprotkb:dPP2A(gene name synonym)|uniprotkb:dPP2A-B56-2(gene name synonym)|uniprotkb:"l(3)S031807"(gene name synonym)|uniprotkb:Widerborst(gene name synonym)|uniprotkb:wbd(gene name synonym)|uniprotkb:CG5643(orf name)|uniprotkb:Dmel_CG5643(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110389|imex:IM-9552-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0037432(gene)|ensemblmetazoa:FBtr0081710(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|reactome:R-DME-5674135|reactome:R-DME-5675221|refseq:NP_649643.1|flybase:FBgn0037432 refseq:NP_733219.1|refseq:NP_651569.1|refseq:NP_733215.1|refseq:NP_733216.1|refseq:NP_733217.1|refseq:NP_733218.1|flybase:FBgn0027492|ensemblmetazoa:FBgn0027492(gene)|ensemblmetazoa:FBtr0085203(transcript)|ensemblmetazoa:FBtr0085204(transcript)|ensemblmetazoa:FBtr0085205(transcript)|ensemblmetazoa:FBtr0085207(transcript)|ensemblmetazoa:FBtr0085208(transcript)|ensemblmetazoa:FBtr0085209(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051225"(spindle assembly)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-DME-432620|reactome:R-DME-432626|dip:DIP-19620N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:68J+UYWUSs3GrPMiPJfbSLQTSS87227 rogid:mINGBJs/U8pIYmRU2yhtZrMEe7Y7227 intact-crc:7596BCA7E9834E55|rigid:YEyBD7pCc5Ab+AJvFkZ30dVmgD8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P34739 uniprotkb:Q86B87 intact:EBI-190656|uniprotkb:Q9VHY1|ensemblmetazoa:FBpp0081255 intact:EBI-124784|uniprotkb:A1A725|uniprotkb:A8JR64|uniprotkb:A8JR66|ensemblmetazoa:FBpp0083478|uniprotkb:P91932|uniprotkb:Q24099|uniprotkb:Q24100|uniprotkb:Q24101|uniprotkb:Q24482|uniprotkb:Q24483|uniprotkb:Q86B84|uniprotkb:Q86B85|uniprotkb:Q86B86|uniprotkb:Q8IN28|uniprotkb:Q8IN29|uniprotkb:Q8IN30|uniprotkb:Q8IN31|uniprotkb:Q8IN32|uniprotkb:Q8IN33|uniprotkb:Q8IN34|uniprotkb:Q8WTI9|uniprotkb:Q8WTJ0|uniprotkb:Q8WTJ1|uniprotkb:Q95R78|uniprotkb:Q95ZF4|uniprotkb:Q95ZF5|uniprotkb:Q95ZF6|uniprotkb:Q95ZF7|uniprotkb:Q95ZF8|uniprotkb:Q9N6U6|uniprotkb:Q9N6U7|uniprotkb:Q9N6U8|uniprotkb:Q9N6U9|uniprotkb:Q9N6V0|uniprotkb:Q9N6V1|uniprotkb:Q9N6V2|uniprotkb:Q9N6V3|uniprotkb:Q9N6V4|uniprotkb:Q9N6V5|uniprotkb:Q9N6V6|uniprotkb:Q9N6V7|uniprotkb:Q9N6V8|uniprotkb:Q9N6V9|uniprotkb:Q9N6W0|uniprotkb:Q9N6W1|uniprotkb:Q9N6W2|uniprotkb:Q9N6W3|uniprotkb:Q9N6W4|uniprotkb:Q9N6W5|uniprotkb:Q9VDA9|uniprotkb:Q9VDB2|uniprotkb:Q9VDB3|uniprotkb:Q9VDB4|uniprotkb:Q9VDB5 psi-mi:ttf2_drome(display_long)|uniprotkb:lds(gene name)|psi-mi:lds(display_short)|uniprotkb:CG2684(orf name)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Protein lodestar(gene name synonym) psi-mi:mmd4_drome(display_long)|uniprotkb:"mod(mdg4)"(gene name)|psi-mi:"mod(mdg4)"(display_short)|uniprotkb:bpd(gene name synonym)|uniprotkb:doom(gene name synonym)|uniprotkb:"E(var)3-93D"(gene name synonym)|uniprotkb:CG32491(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110394|imex:IM-9552-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524850.2|flybase:FBgn0002542|dip:DIP-20026N|ensemblmetazoa:FBgn0002542(gene)|ensemblmetazoa:FBtr0081758(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718 ensemblmetazoa:FBgn0002781(gene)|ensemblmetazoa:FBtr0084079(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007141"(male meiosis I)|go:"GO:0008354"(germ cell migration)|refseq:NP_001097856.1|refseq:NP_001097857.1|refseq:NP_001097858.1|refseq:NP_524936.2|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0031208"(POZ domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|refseq:NP_732619.1|refseq:NP_732620.1|refseq:NP_732621.1|refseq:NP_732622.1|refseq:NP_732624.1|refseq:NP_732625.1|refseq:NP_732626.1|refseq:NP_732627.1|refseq:NP_732628.1|refseq:NP_732629.1|refseq:NP_732630.1|refseq:NP_732631.1|refseq:NP_732632.1|refseq:NP_732633.1|refseq:NP_732634.1|refseq:NP_732635.1|refseq:NP_732636.1|flybase:FBgn0002781|refseq:NP_732623.2|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007588(Zinc finger, FLYWCH-type)|interpro:IPR011333(BTB/POZ fold)|mint:Q86B87|refseq:NP_788698.1|refseq:NP_788699.1|refseq:NP_788700.1|refseq:NP_788701.1|refseq:NP_788702.1|refseq:NP_788703.1|refseq:NP_788704.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:20binWKcS1gIwDKU1sqGSWnkCI47227 rogid:b2OX/raroy6BMkaSC4EuYYprayM7227 intact-crc:3DBDA2619133533A|rigid:/KEp2FaCns1tdwcP2ZRbfjMyMGg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXW3 uniprotkb:Q9VTE9 intact:EBI-166026|ensemblmetazoa:FBpp0073835|uniprotkb:Q960Y1 intact:EBI-189741|intact:EBI-1631593|uniprotkb:Q8IHE1|uniprotkb:B6IDX9|ensemblmetazoa:FBpp0075938|ensemblmetazoa:FBpp0303606 psi-mi:q9vxw3_drome(display_long)|uniprotkb:Dmel\CG12608(gene name)|psi-mi:Dmel\CG12608(display_short)|uniprotkb:CG12608(orf name)|uniprotkb:Dmel_CG12608(orf name) psi-mi:ula1_drome(display_long)|uniprotkb:APP-BP1(gene name)|psi-mi:APP-BP1(display_short)|uniprotkb:CG7828(orf name)|uniprotkb:Beta-amyloid precursor binding protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110404|imex:IM-9552-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0074018(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|ensemblmetazoa:FBgn0030630(gene)|refseq:NP_573019.1|flybase:FBgn0030630 refseq:NP_648435.1|flybase:FBgn0261112|refseq:NP_001261699.1|dip:DIP-21214N|ensemblmetazoa:FBgn0261112(gene)|ensemblmetazoa:FBtr0076208(transcript)|ensemblmetazoa:FBtr0331179(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019781"(NEDD8 activating enzyme activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR030667|interpro:IPR035985 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cnH75G6LB7REYv2Sa/ySy1JROho7227 rogid:prSDFCbav1abEwsjsgImhmN8w3M7227 intact-crc:136A53D0A6CCFA34|rigid:W4XHwJikvGR+gTNNO8qR6AwkBWI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q27415 uniprotkb:O61231 intact:EBI-235255|intact:EBI-1631583|uniprotkb:Q540W3|uniprotkb:Q24565|uniprotkb:Q9VAC3|ensemblmetazoa:FBpp0084918|ensemblmetazoa:FBpp0306756 intact:EBI-123907|uniprotkb:Q86NY2|uniprotkb:Q9I813|uniprotkb:Q9W5T1|uniprotkb:Q0E8B5|intact:EBI-2508530|ensemblmetazoa:FBpp0289147|ensemblmetazoa:FBpp0289148|ensemblmetazoa:FBpp0306039 psi-mi:nlp_drome(display_long)|uniprotkb:Nlp(gene name)|psi-mi:Nlp(display_short)|uniprotkb:CRP1(gene name synonym)|uniprotkb:CG7917(orf name)|uniprotkb:dNLP(gene name synonym)|uniprotkb:Chromatin decondensation protein 1(gene name synonym) psi-mi:rl10_drome(display_long)|uniprotkb:dQM(gene name synonym)|uniprotkb:RpL10(gene name)|psi-mi:RpL10(display_short)|uniprotkb:QM protein homolog(gene name synonym)|uniprotkb:Qm(gene name synonym)|uniprotkb:CG17521(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110399|imex:IM-9552-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524557.1|flybase:FBgn0016685|refseq:NP_001263094.1|dip:DIP-21663N|ensemblmetazoa:FBgn0016685(gene)|ensemblmetazoa:FBtr0085552(transcript)|ensemblmetazoa:FBtr0334701(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|rcsb pdb:1NLQ|reactome:R-DME-3899300|reactome:R-DME-8869496 refseq:NP_651954.3|refseq:NP_730773.4|flybase:FBgn0024733|ensemblmetazoa:FBgn0024733(gene)|ensemblmetazoa:FBtr0299869(transcript)|ensemblmetazoa:FBtr0299870(transcript)|ensemblmetazoa:FBtr0333910(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0043025"(neuronal cell body)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-72689|reactome:R-DME-72706|reactome:R-DME-975956|reactome:R-DME-975957|refseq:NP_001262233.1|dip:DIP-18809N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:QrY87I8Muib7Pc95YiJtKyv9ZuA7227 rogid:6wI5IuUUZKfvDQl/bSfDOGKQE2g7227 intact-crc:AF3A270BB576AA4C|rigid:jnk5U6mbTIuOqFlH057YrwZgd4Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VI08 uniprotkb:E4NKJ7 intact:EBI-89535|ensemblmetazoa:FBpp0081207 intact:EBI-2109097|ensemblmetazoa:FBpp0071844 psi-mi:q9vi08_drome(display_long)|uniprotkb:"BcDNA:GH28351"(gene name)|psi-mi:"BcDNA:GH28351"(display_short)|uniprotkb:Dmel\CG10298(gene name synonym)|uniprotkb:CG10298(orf name)|uniprotkb:Dmel_CG10298(orf name) psi-mi:e4nkj7_drome(display_long)|uniprotkb:CG2852-RA(gene name)|psi-mi:CG2852-RA(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110409|imex:IM-9552-548 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0037432(gene)|ensemblmetazoa:FBtr0081710(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|reactome:R-DME-5674135|reactome:R-DME-5675221|refseq:NP_649643.1|flybase:FBgn0037432 interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR024936|interpro:IPR029000|ensemblmetazoa:FBgn0034753(gene)|ensemblmetazoa:FBtr0071933(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:68J+UYWUSs3GrPMiPJfbSLQTSS87227 rogid:3aIBAqr3Fyg0C5AlSkwGpkjAE4c7227 intact-crc:7F7F49D7994D7E7A|rigid:gOAbIkKzP26ZmmZd1V4Ov46w1dA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VEM2 uniprotkb:Q9VEM2 intact:EBI-137031|ensemblmetazoa:FBpp0082849 intact:EBI-137031|ensemblmetazoa:FBpp0082849 psi-mi:q9vem2_drome(display_long)|uniprotkb:Dmel\CG12265(gene name synonym)|uniprotkb:det(gene name synonym)|uniprotkb:scpo(gene name synonym)|uniprotkb:svn(gene name synonym)|uniprotkb:Dmel_CG12265(orf name)|uniprotkb:Det(gene name)|psi-mi:Det(display_short)|uniprotkb:CG12265(orf name) psi-mi:q9vem2_drome(display_long)|uniprotkb:Dmel\CG12265(gene name synonym)|uniprotkb:det(gene name synonym)|uniprotkb:scpo(gene name synonym)|uniprotkb:svn(gene name synonym)|uniprotkb:Dmel_CG12265(orf name)|uniprotkb:Det(gene name)|psi-mi:Det(display_short)|uniprotkb:CG12265(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110414|imex:IM-9552-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650608.1|flybase:FBgn0264291|ensemblmetazoa:FBgn0264291(gene)|ensemblmetazoa:FBtr0083408(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051225"(spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis) refseq:NP_650608.1|flybase:FBgn0264291|ensemblmetazoa:FBgn0264291(gene)|ensemblmetazoa:FBtr0083408(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051225"(spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sH8qmL+6huHPZMjf8OJsYXvaLG47227 rogid:sH8qmL+6huHPZMjf8OJsYXvaLG47227 intact-crc:9CEE644E37974CA5|rigid:GgH5JlQniFnQYtMJLismECbBNW4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG26 uniprotkb:P31007 intact:EBI-2110419|ensemblmetazoa:FBpp0082157 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 psi-mi:q9vg26_drome(display_long)|uniprotkb:CG10135(gene name)|psi-mi:CG10135(display_short)|uniprotkb:CBP9(gene name synonym)|uniprotkb:CG14388(gene name synonym)|uniprotkb:CG31345-RA(gene name synonym)|uniprotkb:Dmel\CG31345(gene name synonym)|uniprotkb:CG31345(orf name)|uniprotkb:Dmel_CG31345(orf name) psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110423|imex:IM-9552-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731744.1|flybase:FBgn0051345|ensemblmetazoa:FBgn0051345(gene)|ensemblmetazoa:FBtr0082689(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247 refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:x+nwoiGgKT7bfEIjACR17DYHUv07227 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 intact-crc:E5C3619A0C557C6D|rigid:9XieqT+1KWn15+Z4EAmbJdQaiT0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VR83 uniprotkb:Q8MYY3 intact:EBI-175651|ensemblmetazoa:FBpp0297617|ensemblmetazoa:FBpp0307044|ensemblmetazoa:FBpp0307045|ensemblmetazoa:FBpp0307046 intact:EBI-1631706|ensemblmetazoa:FBpp0079549 psi-mi:q9vr83_drome(display_long)|uniprotkb:CT3673(gene name)|psi-mi:CT3673(display_short)|uniprotkb:1504(gene name synonym)|uniprotkb:Dmel\CG1504(gene name synonym)|uniprotkb:CG1504(orf name)|uniprotkb:Dmel_CG1504(orf name) psi-mi:q8myy3_drome(display_long)|uniprotkb:CG5731(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110428|imex:IM-9552-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0031100|refseq:NP_608382.2|refseq:NP_001259742.1|refseq:NP_001259743.1|refseq:NP_001259744.1|ensemblmetazoa:FBgn0031100(gene)|ensemblmetazoa:FBtr0306678(transcript)|ensemblmetazoa:FBtr0335040(transcript)|ensemblmetazoa:FBtr0335041(transcript)|ensemblmetazoa:FBtr0335042(transcript)|go:"GO:0005886"(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR026906|interpro:IPR032675 flybase:FBgn0032192|ensemblmetazoa:FBgn0032192(gene)|ensemblmetazoa:FBtr0079959(transcript)|go:"GO:0004557"(alpha-galactosidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0046477"(glycosylceramide catabolic process)|interpro:IPR000111(Glycoside hydrolase, clan GH-D)|interpro:IPR002241(Glycoside hydrolase, family 27)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR035373 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:zgrGORokbSXYw8r2igNGeNtgmiM7227 rogid:3Sb4KYGAq8kRlNJcVqWn7M4AOsY7227 intact-crc:8A3EEEC6BF27D947|rigid:YWCsKAvUkX7HIFMQIwzxvnQ1bvw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O96880 uniprotkb:P51406 intact:EBI-114089|ensemblmetazoa:FBpp0075839 intact:EBI-117198|uniprotkb:Q9W3N3|ensemblmetazoa:FBpp0071046 psi-mi:o96880_drome(display_long)|uniprotkb:TfIIEalpha(gene name)|psi-mi:TfIIEalpha(display_short)|uniprotkb:TfIIE-alpha(gene name synonym)|uniprotkb:CG10415(orf name)|uniprotkb:Dmel\CG10415(gene name synonym)|uniprotkb:TFIIE(gene name synonym)|uniprotkb:TFIIE-L(gene name synonym)|uniprotkb:TFIIEalpha(gene name synonym)|uniprotkb:TfIIE(gene name synonym)|uniprotkb:TfIIEa(gene name synonym)|uniprotkb:dTFIIE-L(gene name synonym)|uniprotkb:dTFIIEL(gene name synonym)|uniprotkb:Dmel_CG10415(orf name) psi-mi:bys_drome(display_long)|uniprotkb:bys(gene name)|psi-mi:bys(display_short)|uniprotkb:CG1430(orf name)|uniprotkb:Protein bys(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110433|imex:IM-9552-550 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015828(gene)|ensemblmetazoa:FBtr0076108(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|reactome:R-DME-674695|refseq:NP_524026.1|flybase:FBgn0015828 refseq:NP_511074.1|flybase:FBgn0010292|ensemblmetazoa:FBgn0010292(gene)|ensemblmetazoa:FBtr0071090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR007955(Bystin)|dip:DIP-19855N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:2GWSDJ4jNq2wCYKTZtmhqQnskwA7227 rogid:+a0Azeyc1t5adGw9xM6QwZiMevI7227 intact-crc:F00B312989A50AFA|rigid:gtSkWRgAnz5pjsNzOmvk5nT4DIA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) intact:EBI-106875 uniprotkb:Q8MR10 intact:EBI-2110443 intact:EBI-2110451|ensemblmetazoa:FBpp0081662 psi-mi:a1z7p0_drome(display_short)|psi-mi:EBI-106875(display_long)|uniprotkb:Pmm45A(gene name)|psi-mi:Pmm45A(display_short)|uniprotkb:Dmel_CG8073(orf name)|uniprotkb:CG8073(orf name) psi-mi:q8mr10_drome(display_long)|uniprotkb:CG6254(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110448|imex:IM-9552-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1Z7P0(uniprot-removed-ac) flybase:FBgn0037794|ensemblmetazoa:FBgn0037794(gene)|ensemblmetazoa:FBtr0082184(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:IIS/qfvWnOmztqGMBNv0rhx58287227 rogid:/AmwdMXzrAK5ljUjZ0M3yv1FUiE7227 intact-crc:B2C5F26BBB16D397|rigid:OIQJxlfR1d79t4YKyJxkyoIU27g false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z6R7 uniprotkb:Q5U160 intact:EBI-129513|intact:EBI-2109687|ensemblmetazoa:FBpp0085498 intact:EBI-2110456 psi-mi:a1z6r7_drome(display_long)|uniprotkb:Dmel\CG30158(gene name)|psi-mi:Dmel\CG30158(display_short)|uniprotkb:"BcDNA:RE28276"(gene name synonym)|uniprotkb:CG15243(gene name synonym)|uniprotkb:CG15244(gene name synonym)|uniprotkb:CG30158-RA(gene name synonym)|uniprotkb:CG9464(gene name synonym)|uniprotkb:CG30158(orf name)|uniprotkb:Dmel_CG30158(orf name) psi-mi:q5u160_drome(display_long)|uniprotkb:CG5290(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110459|imex:IM-9552-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652315.2|flybase:FBgn0050158|ensemblmetazoa:FBgn0050158(gene)|ensemblmetazoa:FBtr0086165(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0019003"(GDP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417 flybase:FBgn0036772|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044244 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+xMPp3QnmfnUKCqzJNqp4JQcOVo7227 rogid:bVL56br68O+rRdgrkP3Uq5mMv387227 intact-crc:39B989E095207B28|rigid:rHlzJ86ADV31i50OJVdseewlnXU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O96794 intact:EBI-2108411 intact:EBI-2108391 - psi-mi:o96794_drome(display_long)|uniprotkb:Daminopep-p(gene name synonym)|uniprotkb:ApepP(gene name)|psi-mi:ApepP(display_short)|uniprotkb:CG6291(orf name) psi-mi:q8img7_drome(display_short)|psi-mi:EBI-2108411(display_long)|uniprotkb:Dmel_CG11525(orf name)|uniprotkb:CycG(gene name)|psi-mi:CycG(display_short)|uniprotkb:CG11525(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110438|imex:IM-9552-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026150|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR000587(Creatinase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR029149|interpro:IPR032416|interpro:IPR033740|interpro:IPR036005 uniprotkb:Q8IMG7(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:v0cFpC+s9qA6wE1X8tFRAgthzPc7227 rogid:GwDM/XQ/mtqkftw2t9BwmojZmFA7227 intact-crc:1477B4172C1A1E89|rigid:S2PSx+FrDf594pez16oqfZ5pwRk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z833 uniprotkb:Q8T0T9 intact:EBI-2110474|ensemblmetazoa:FBpp0087522 intact:EBI-2110469|uniprotkb:Q9W0B4|ensemblmetazoa:FBpp0072644|ensemblmetazoa:FBpp0312183 psi-mi:a1z833_drome(display_long)|uniprotkb:Dmel\CG1407(gene name)|psi-mi:Dmel\CG1407(display_short)|uniprotkb:CG1407(orf name)|uniprotkb:Dmel_CG1407(orf name) psi-mi:q8t0t9_drome(display_long)|uniprotkb:CG13920(orf name)|uniprotkb:"BEST:CK00246"(gene name)|psi-mi:"BEST:CK00246"(display_short)|uniprotkb:CK00246(gene name synonym)|uniprotkb:Dmel\CG13920(gene name synonym)|uniprotkb:Dmel_CG13920(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110477|imex:IM-9552-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_724868.2|flybase:FBgn0033474|ensemblmetazoa:FBgn0033474(gene)|ensemblmetazoa:FBtr0088436(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type) refseq:NP_647639.1|flybase:FBgn0025712|refseq:NP_001286902.1|ensemblmetazoa:FBgn0025712(gene)|ensemblmetazoa:FBtr0072761(transcript)|ensemblmetazoa:FBtr0346593(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR029693|interpro:IPR032808|interpro:IPR040399 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:dg81/7gI8Fi0Yb1Wv4nz1BeWtzc7227 rogid:y2M41YJUeBWEfMKF3AdzZAtQNzc7227 intact-crc:E60AA9E3588F3689|rigid:hL+XjNDRVn0oKTNfZ6MXz9jH1yU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VHP1 uniprotkb:P56079 intact:EBI-194830|ensemblmetazoa:FBpp0081368 intact:EBI-86600|uniprotkb:Q9VSE0|ensemblmetazoa:FBpp0076411|ensemblmetazoa:FBpp0312164 psi-mi:q9vhp1_drome(display_long)|uniprotkb:Dmel_CG11753(orf name)|uniprotkb:CG11753(orf name)|uniprotkb:Sys1(gene name)|psi-mi:Sys1(display_short)|uniprotkb:Dmel\CG11753(gene name synonym) psi-mi:cds_drome(display_long)|uniprotkb:Cds(gene name)|psi-mi:Cds(display_short)|uniprotkb:CDP-DAG synthase(gene name synonym)|uniprotkb:CDP-DG synthase(gene name synonym)|uniprotkb:CDP-diacylglycerol synthase(gene name synonym)|uniprotkb:CDP-diglyceride pyrophosphorylase(gene name synonym)|uniprotkb:CDP-diglyceride synthase(gene name synonym)|uniprotkb:"CTP:phosphatidate cytidylyltransferase"(gene name synonym)|uniprotkb:CdsA(gene name synonym)|uniprotkb:CG7962(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110464|imex:IM-9552-552 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649809.1|flybase:FBgn0037603|ensemblmetazoa:FBgn0037603(gene)|ensemblmetazoa:FBtr0081879(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR016973(SYS1 homologue)|interpro:IPR019185|reactome:R-DME-6811440 refseq:NP_524661.1|flybase:FBgn0010350|ensemblmetazoa:FBgn0010350(gene)|ensemblmetazoa:FBtr0076688(transcript)|ensemblmetazoa:FBtr0346546(transcript)|go:"GO:0004605"(phosphatidate cytidylyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007291"(sperm individualization)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0010868"(negative regulation of triglyceride biosynthetic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0043052"(thermotaxis)|interpro:IPR000374(Phosphatidate cytidylyltransferase)|interpro:IPR016720(Phosphatidate cytidylyltransferase, eukaryota)|reactome:R-DME-1483148|reactome:R-DME-1483226|refseq:NP_001286976.1|dip:DIP-23447N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:QAepeTgKKbklRPRyW3Zr+ACadbU7227 rogid:GoPSSG6igMwB9R0ZyJuOhgTm7Mw7227 intact-crc:973B8BCC526E3C6B|rigid:SfkIj0l7qWGm1NSgqgvPfejiCQU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24337 uniprotkb:Q8SYC8 intact:EBI-169459|intact:EBI-1631667|uniprotkb:A4V463|uniprotkb:Q9W3B1|ensemblmetazoa:FBpp0071209|ensemblmetazoa:FBpp0071210|ensemblmetazoa:FBpp0301768|ensemblmetazoa:FBpp0305781|ensemblmetazoa:FBpp0305782 intact:EBI-2109185 psi-mi:er_drome(display_long)|uniprotkb:"e(r)"(gene name)|psi-mi:"e(r)"(display_short)|uniprotkb:CG1871(orf name) psi-mi:q8syc8_drome(display_long)|uniprotkb:CG15481(orf name)|uniprotkb:Ski6(gene name)|psi-mi:Ski6(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110487|imex:IM-9552-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011586(gene)|ensemblmetazoa:FBtr0071266(transcript)|ensemblmetazoa:FBtr0071267(transcript)|ensemblmetazoa:FBtr0310067(transcript)|ensemblmetazoa:FBtr0333604(transcript)|ensemblmetazoa:FBtr0333605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007049"(cell cycle)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|refseq:NP_524662.1|refseq:NP_727293.1|flybase:FBgn0011586|refseq:NP_001259363.1|refseq:NP_001259364.1|refseq:NP_001259365.1|dip:DIP-19260N flybase:FBgn0032487|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:f4fk70qMBG+f0rMJe53JbAF8Lhg7227 rogid:11s6l6e8OGtwBuVKtc3fX82Pztg7227 intact-crc:0D715AE0AD69A6CA|rigid:ScBhq6i+GD8wS6czW5yrOYZB5vI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN41 uniprotkb:Q86B87 intact:EBI-186581|uniprotkb:Q058Y9|ensemblmetazoa:FBpp0290511 intact:EBI-124784|uniprotkb:A1A725|uniprotkb:A8JR64|uniprotkb:A8JR66|ensemblmetazoa:FBpp0083478|uniprotkb:P91932|uniprotkb:Q24099|uniprotkb:Q24100|uniprotkb:Q24101|uniprotkb:Q24482|uniprotkb:Q24483|uniprotkb:Q86B84|uniprotkb:Q86B85|uniprotkb:Q86B86|uniprotkb:Q8IN28|uniprotkb:Q8IN29|uniprotkb:Q8IN30|uniprotkb:Q8IN31|uniprotkb:Q8IN32|uniprotkb:Q8IN33|uniprotkb:Q8IN34|uniprotkb:Q8WTI9|uniprotkb:Q8WTJ0|uniprotkb:Q8WTJ1|uniprotkb:Q95R78|uniprotkb:Q95ZF4|uniprotkb:Q95ZF5|uniprotkb:Q95ZF6|uniprotkb:Q95ZF7|uniprotkb:Q95ZF8|uniprotkb:Q9N6U6|uniprotkb:Q9N6U7|uniprotkb:Q9N6U8|uniprotkb:Q9N6U9|uniprotkb:Q9N6V0|uniprotkb:Q9N6V1|uniprotkb:Q9N6V2|uniprotkb:Q9N6V3|uniprotkb:Q9N6V4|uniprotkb:Q9N6V5|uniprotkb:Q9N6V6|uniprotkb:Q9N6V7|uniprotkb:Q9N6V8|uniprotkb:Q9N6V9|uniprotkb:Q9N6W0|uniprotkb:Q9N6W1|uniprotkb:Q9N6W2|uniprotkb:Q9N6W3|uniprotkb:Q9N6W4|uniprotkb:Q9N6W5|uniprotkb:Q9VDA9|uniprotkb:Q9VDB2|uniprotkb:Q9VDB3|uniprotkb:Q9VDB4|uniprotkb:Q9VDB5 psi-mi:slx1_drome(display_long)|uniprotkb:CG18271(orf name)|uniprotkb:slx1(gene name)|psi-mi:slx1(display_short) psi-mi:mmd4_drome(display_long)|uniprotkb:"mod(mdg4)"(gene name)|psi-mi:"mod(mdg4)"(display_short)|uniprotkb:bpd(gene name synonym)|uniprotkb:doom(gene name synonym)|uniprotkb:"E(var)3-93D"(gene name synonym)|uniprotkb:CG32491(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110482|imex:IM-9552-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649484.3|flybase:FBgn0037263|ensemblmetazoa:FBgn0037263(gene)|ensemblmetazoa:FBtr0301296(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0033557"(Slx1-Slx4 complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR026850|interpro:IPR027520|interpro:IPR035901|reactome:R-DME-5693568 ensemblmetazoa:FBgn0002781(gene)|ensemblmetazoa:FBtr0084079(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007141"(male meiosis I)|go:"GO:0008354"(germ cell migration)|refseq:NP_001097856.1|refseq:NP_001097857.1|refseq:NP_001097858.1|refseq:NP_524936.2|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0031208"(POZ domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|refseq:NP_732619.1|refseq:NP_732620.1|refseq:NP_732621.1|refseq:NP_732622.1|refseq:NP_732624.1|refseq:NP_732625.1|refseq:NP_732626.1|refseq:NP_732627.1|refseq:NP_732628.1|refseq:NP_732629.1|refseq:NP_732630.1|refseq:NP_732631.1|refseq:NP_732632.1|refseq:NP_732633.1|refseq:NP_732634.1|refseq:NP_732635.1|refseq:NP_732636.1|flybase:FBgn0002781|refseq:NP_732623.2|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007588(Zinc finger, FLYWCH-type)|interpro:IPR011333(BTB/POZ fold)|mint:Q86B87|refseq:NP_788698.1|refseq:NP_788699.1|refseq:NP_788700.1|refseq:NP_788701.1|refseq:NP_788702.1|refseq:NP_788703.1|refseq:NP_788704.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uL5oV5TWys5torll6MvTqyZC1r07227 rogid:b2OX/raroy6BMkaSC4EuYYprayM7227 intact-crc:1B8119A897217DB3|rigid:SlZCQUjc7sDU0WhwynPv1ITYXuw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W3Y3 uniprotkb:Q9VG93 intact:EBI-2110492|ensemblmetazoa:FBpp0070953 intact:EBI-2110499|uniprotkb:Q4V3S1|uniprotkb:Q9TX87|ensemblmetazoa:FBpp0082046 psi-mi:q9w3y3_drome(display_long)|uniprotkb:Dmel\CG3226(gene name)|psi-mi:Dmel\CG3226(display_short)|uniprotkb:Q9W3Y3(gene name synonym)|uniprotkb:CG3226(orf name)|uniprotkb:Dmel_CG3226(orf name) psi-mi:gstd7_drome(display_long)|uniprotkb:gstD26(gene name synonym)|uniprotkb:CG4371(orf name)|uniprotkb:GstD7(gene name)|psi-mi:GstD7(display_short)|uniprotkb:GSTD7-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110496|imex:IM-9552-554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572332.1|flybase:FBgn0029882|ensemblmetazoa:FBgn0029882(gene)|ensemblmetazoa:FBtr0070993(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0015631"(tubulin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044548"(S100 protein binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893 refseq:NP_525114.1|flybase:FBgn0010043|ensemblmetazoa:FBgn0010043(gene)|ensemblmetazoa:FBtr0082574(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009636"(response to toxic substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:btXDxLSH1VBNdWKeHqDfbD13yxI7227 rogid:J9rd4Py+/bNnZrBjn4D7qrm26ak7227 intact-crc:A77E132D0FB0335A|rigid:qz865QBdcbU8fGcMdyPjoEtiF2Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VG79 uniprotkb:Q9VED4 intact:EBI-2110505|uniprotkb:Q95RW4|ensemblmetazoa:FBpp0082069|ensemblmetazoa:FBpp0311237 intact:EBI-141777|ensemblmetazoa:FBpp0082965 psi-mi:q9vg79_drome(display_long)|uniprotkb:CG5663(orf name)|uniprotkb:Dip-C(gene name)|psi-mi:Dip-C(display_short)|uniprotkb:Dmel\CG5663(gene name synonym)|uniprotkb:dipC(gene name synonym)|uniprotkb:Dmel_CG5663(orf name) psi-mi:q9ved4_drome(display_long)|uniprotkb:anon-WO0172774.95(gene name)|psi-mi:anon-WO0172774.95(display_short)|uniprotkb:CG14317-RA(gene name synonym)|uniprotkb:Dmel\CG14317(gene name synonym)|uniprotkb:CG14317(orf name)|uniprotkb:Dmel_CG14317(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110510|imex:IM-9552-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650192.1|flybase:FBgn0000455|refseq:NP_001287306.1|ensemblmetazoa:FBgn0000455(gene)|ensemblmetazoa:FBtr0082597(transcript)|ensemblmetazoa:FBtr0344982(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal)|interpro:IPR029149|interpro:IPR036005 refseq:NP_650675.1|flybase:FBgn0038566|ensemblmetazoa:FBgn0038566(gene)|ensemblmetazoa:FBtr0083541(transcript)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR032675 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:REw165uOy+NXO1xk2EHqOq6BzWs7227 rogid:Q1EFfcMm8uQBuClff2GXRDKaDTc7227 intact-crc:246B575DE93D171A|rigid:xwO2WAB4n2nN5Bj4JGyhUzw9XZE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VUL1 uniprotkb:Q9VTE0 intact:EBI-132528|uniprotkb:Q9VUL0|ensemblmetazoa:FBpp0310803|ensemblmetazoa:FBpp0311740 intact:EBI-87041|ensemblmetazoa:FBpp0075932 psi-mi:pyrg_drome(display_long)|uniprotkb:CTP synthetase(gene name synonym)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:CTPsyn(gene name)|psi-mi:CTPsyn(display_short)|uniprotkb:CG45070(orf name) psi-mi:bl1s2_drome(display_long)|uniprotkb:Blos2(gene name)|psi-mi:Blos2(display_short)|uniprotkb:CG14145(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110520|imex:IM-9552-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648747.1|refseq:NP_730023.1|refseq:NP_001287067.1|flybase:FBgn0266452|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:6L6Z|rcsb pdb:6LFG|reactome:R-DME-499943|ensemblmetazoa:FBgn0266452(gene)|ensemblmetazoa:FBtr0344431(transcript)|ensemblmetazoa:FBtr0345691(transcript)|go:"GO:0003883"(CTP synthase activity) ensemblmetazoa:FBgn0036118(gene)|ensemblmetazoa:FBtr0076202(transcript)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032418"(lysosome localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0099078"(BORC complex)|interpro:IPR019269|refseq:NP_648427.1|flybase:FBgn0036118 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:CO28Z1AFivaEc66iMYDqkzsC2G47227 rogid:bTHARl+MiwEUHncl2vsedXacjh47227 intact-crc:B5423F121C577CA5|rigid:zBvJQGAyDmnnV7hauYNZdwgZ8+8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XZH6 uniprotkb:Q9VHU1 intact:EBI-86624|ensemblmetazoa:FBpp0083214|ensemblmetazoa:FBpp0311933 intact:EBI-2108869|ensemblmetazoa:FBpp0081355 psi-mi:vatg_drome(display_long)|uniprotkb:Vha13(gene name)|psi-mi:Vha13(display_short)|uniprotkb:CG6213(orf name)|uniprotkb:Vacuolar proton pump subunit G(gene name synonym)|uniprotkb:V-ATPase 13 kDa subunit(gene name synonym) psi-mi:ddx55_drome(display_long)|uniprotkb:CG9630(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110515|imex:IM-9552-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477437.1|ensemblmetazoa:FBgn0283536(gene)|ensemblmetazoa:FBtr0083804(transcript)|ensemblmetazoa:FBtr0346100(transcript)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|flybase:FBgn0283536|refseq:NP_001287407.1|dip:DIP-18952N refseq:NP_649777.1|flybase:FBgn0037561|ensemblmetazoa:FBgn0037561(gene)|ensemblmetazoa:FBtr0081866(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+Leuvn9tI2xSpSgxm3xx4ObyAFU7227 rogid:fe2Mvxqfx49xTpnXeM2syc+ZwIQ7227 intact-crc:550C12B4B1E92A16|rigid:93ftgSG9GE472wW6p/733Gurs+o false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VGG5 uniprotkb:Q9VIZ0 intact:EBI-2110530|uniprotkb:Q8MQL5|ensemblmetazoa:FBpp0081987 intact:EBI-89092|uniprotkb:Q0IGY9|ensemblmetazoa:FBpp0080704 psi-mi:cad87_drome(display_long)|uniprotkb:CG6977(orf name)|uniprotkb:Cad87A(gene name)|psi-mi:Cad87A(display_short) psi-mi:rpac2_drome(display_long)|uniprotkb:"l(2)37Cg"(gene name)|psi-mi:"l(2)37Cg"(display_short)|uniprotkb:CG10685(orf name)|uniprotkb:AC19(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit D(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110535|imex:IM-9552-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731649.2|flybase:FBgn0037963|ensemblmetazoa:FBgn0037963(gene)|ensemblmetazoa:FBtr0082513(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|reactome:R-DME-114608|reactome:R-DME-8980692 refseq:NP_609950.1|flybase:FBgn0086447|ensemblmetazoa:FBgn0086447(gene)|ensemblmetazoa:FBtr0081161(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hOHi/rOLjZHrt2eASIjtlRYqTOk7227 rogid:xvsuNplI/+LbRfYGDAnu+9qpOc07227 intact-crc:9B1F11B159780256|rigid:7bt8/eN3mZTw3zeiwBdPQUSRI7Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24292 uniprotkb:Q7K1Q7 intact:EBI-172077|uniprotkb:Q9VPS4|intact:EBI-3417016|ensemblmetazoa:FBpp0077708 intact:EBI-2108329|ensemblmetazoa:FBpp0087511 psi-mi:ds_drome(display_long)|uniprotkb:ds(gene name)|psi-mi:ds(display_short)|uniprotkb:CG17941(orf name)|uniprotkb:Adherin(gene name synonym) psi-mi:q7k1q7_drome(display_long)|uniprotkb:RpLP0-like(gene name)|psi-mi:RpLP0-like(display_short)|uniprotkb:Dmel\CG1381(gene name synonym)|uniprotkb:CG1381(orf name)|uniprotkb:Dmel_CG1381(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110525|imex:IM-9552-556 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523446.2|refseq:NP_001285551.1|dip:DIP-49190N|flybase:FBgn0284247|ensemblmetazoa:FBgn0284247(gene)|ensemblmetazoa:FBtr0078045(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|reactome:R-DME-350379|reactome:R-DME-390023|reactome:R-DME-390150 refseq:NP_610554.1|flybase:FBgn0033485|ensemblmetazoa:FBgn0033485(gene)|ensemblmetazoa:FBtr0088425(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR033867|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:LI78yfm8bzRIbSH/xD7sHggvsCk7227 rogid:d5/dhfaaAsyuYCgLISMyPYXYRfc7227 intact-crc:4FD59DA2347ECF21|rigid:M79cu+PSAWiGVyOyNXmBEfMs+EM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24040 uniprotkb:A1Z9E3 intact:EBI-136112|intact:EBI-1629706|uniprotkb:Q95TG4|uniprotkb:Q9W0B9|ensemblmetazoa:FBpp0072641 intact:EBI-133675|intact:EBI-2109586|ensemblmetazoa:FBpp0086790|ensemblmetazoa:FBpp0290603 psi-mi:bgb_drome(display_long)|uniprotkb:Bgb(gene name)|psi-mi:Bgb(display_short)|uniprotkb:CG7959(orf name) psi-mi:a1z9e3_drome(display_long)|uniprotkb:mEFTu1(gene name)|psi-mi:mEFTu1(display_short)|uniprotkb:EfTuM(gene name synonym)|uniprotkb:Dmel\CG6050(gene name synonym)|uniprotkb:EF-Tu1(gene name synonym)|uniprotkb:efTuM(gene name synonym)|uniprotkb:eftu-M(gene name synonym)|uniprotkb:"l(3)L4569"(gene name synonym)|uniprotkb:mtEF-Tu(gene name synonym)|uniprotkb:CG6050(orf name)|uniprotkb:Dmel_CG6050(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110548|imex:IM-9552-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477065.3|flybase:FBgn0013753|ensemblmetazoa:FBgn0013753(gene)|ensemblmetazoa:FBtr0072758(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-8931987|reactome:R-DME-8934593|go:"GO:0008134"(transcription factor binding)|reactome:R-DME-8936459|reactome:R-DME-8939236|go:"GO:0016513"(core-binding factor complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|reactome:R-DME-8939243|interpro:IPR003417(Core binding factor, beta subunit)|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|interpro:IPR036552|reactome:R-DME-8878166|reactome:R-DME-8941326|reactome:R-DME-8941858|reactome:R-DME-8951936|reactome:R-DME-9018519|dip:DIP-22891N refseq:NP_001163144.1|refseq:NP_524752.1|flybase:FBgn0024556|ensemblmetazoa:FBgn0024556(gene)|ensemblmetazoa:FBtr0087670(transcript)|ensemblmetazoa:FBtr0301389(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hkF6uzA4PWioYF1W4mK3bAU4EnM7227 rogid:+Cf2LceMe6TUIxKcs4ZOAPsyycQ7227 intact-crc:FC4BAA890004F7A4|rigid:b950RdLVtGUkEuWwt8Te0ZPkTI8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZS0 uniprotkb:Q9VXT4 intact:EBI-131149|ensemblmetazoa:FBpp0083595 intact:EBI-2110543|ensemblmetazoa:FBpp0288957 psi-mi:q8szs0_drome(display_long)|uniprotkb:Dmel\CG31163(gene name synonym)|uniprotkb:Dmel_CG31163(orf name)|uniprotkb:SKIP(gene name)|psi-mi:SKIP(display_short)|uniprotkb:CG13863(gene name synonym)|uniprotkb:CG13864(gene name synonym)|uniprotkb:CG5736(gene name synonym)|uniprotkb:CG7086(gene name synonym)|uniprotkb:CG7087(gene name synonym)|uniprotkb:CG31163(orf name) psi-mi:q9vxt4_drome(display_long)|uniprotkb:CG15644(gene name)|psi-mi:CG15644(display_short)|uniprotkb:CG18620(gene name synonym)|uniprotkb:Dmel\CG42299(gene name synonym)|uniprotkb:E3 SUMO-protein transferase NSE2(gene name synonym)|uniprotkb:Non-structural maintenance of chromosomes element 2 homolog(gene name synonym)|uniprotkb:CG32584(orf name)|uniprotkb:CG42299(orf name)|uniprotkb:Dmel_CG42299(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110540|imex:IM-9552-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732703.1|flybase:FBgn0051163|go:"GO:0007608"(sensory perception of smell)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|ensemblmetazoa:FBtr0084197(transcript)|ensemblmetazoa:FBgn0051163(gene) refseq:NP_727866.2|flybase:FBgn0259195|ensemblmetazoa:FBgn0259195(gene)|ensemblmetazoa:FBtr0299679(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR026846 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:65jEfG3MxCgYJwA2B8/zdZvMK3s7227 rogid:dPEcKJxBypDJQIQgKZ3Qhlr9olY7227 intact-crc:F96C3AAEFB70D4BC|rigid:TJzy/7buFnJL1AcTEC9ZZpjZspw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9I7L0 uniprotkb:Q9VXL4 intact:EBI-98797|intact:EBI-1627416|ensemblmetazoa:FBpp0081273 intact:EBI-95724|intact:EBI-1628917|ensemblmetazoa:FBpp0073937|ensemblmetazoa:FBpp0309613 psi-mi:q9i7l0_drome(display_long)|uniprotkb:Dmel_CG18745(orf name)|uniprotkb:CG18745(orf name)|uniprotkb:Dmel\CG18745(gene name)|psi-mi:Dmel\CG18745(display_short) psi-mi:q9vxl4_drome(display_long)|uniprotkb:Rrp47(gene name)|psi-mi:Rrp47(display_short)|uniprotkb:CG8928-RA(gene name synonym)|uniprotkb:Dmel\CG8928(gene name synonym)|uniprotkb:dRrp47(gene name synonym)|uniprotkb:lincRNA.1007(gene name synonym)|uniprotkb:Dmel_CG8928(orf name)|uniprotkb:CG8928(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110576|imex:IM-9552-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652648.1|flybase:FBgn0042102|ensemblmetazoa:FBgn0042102(gene)|ensemblmetazoa:FBtr0081777(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0140112"(extracellular vesicle biogenesis)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-DME-844456|dip:DIP-21157N refseq:NP_573092.1|flybase:FBgn0030711|refseq:NP_001285310.1|ensemblmetazoa:FBgn0030711(gene)|ensemblmetazoa:FBtr0074132(transcript)|ensemblmetazoa:FBtr0342745(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|reactome:R-DME-6791226 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:4aDTZJ+/8QBHTiXhsrJPn6Xt3207227 rogid:7Sc3MNHqhfXFSlTGyNy22FKHt587227 intact-crc:45812F7C3EF95971|rigid:mnb2DvFKB7TwzK2K3Z8NyWLdfKE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P16909 uniprotkb:Q9XZ19 intact:EBI-2110553|uniprotkb:Q86NM1|uniprotkb:Q9VPA8|ensemblmetazoa:FBpp0077928 intact:EBI-126818|ensemblmetazoa:FBpp0081650 psi-mi:18c_drome(display_long)|uniprotkb:anon-77F(gene name synonym)|uniprotkb:CG3354(orf name)|uniprotkb:18c(gene name synonym)|uniprotkb:Mst77F(gene name)|psi-mi:Mst77F(display_short) psi-mi:q9xz19_drome(display_long)|uniprotkb:Dmel\CG3909(gene name)|psi-mi:Dmel\CG3909(display_short)|uniprotkb:"BcDNA:LD21537"(gene name synonym)|uniprotkb:CG3039(gene name synonym)|uniprotkb:Ski8(gene name synonym)|uniprotkb:dSki8(gene name synonym)|uniprotkb:CG3909(orf name)|uniprotkb:Dmel_CG3909(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110558|imex:IM-9552-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524188.1|flybase:FBgn0086915|ensemblmetazoa:FBgn0086915(gene)|ensemblmetazoa:FBtr0078270(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0035042"(fertilization, exchange of chromosomal proteins)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0036126"(sperm flagellum) refseq:NP_649969.1|flybase:FBgn0027524|ensemblmetazoa:FBgn0027524(gene)|ensemblmetazoa:FBtr0082172(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|reactome:R-DME-75955|reactome:R-DME-8866654|reactome:R-DME-112382|reactome:R-DME-429958|reactome:R-DME-674695 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ID0oxHatT3MRTh4K0Gwgxti2VYk7227 rogid:4FYdLrsKcLwU2rszqFIEILUgL6M7227 intact-crc:01BD084B313F611E|rigid:oxCOaMYj0q4eTJHsiSA0ZAjCulA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P41073-1 uniprotkb:Q7K4G8 intact:EBI-522343|ensemblmetazoa:FBpp0074963 intact:EBI-149092|intact:EBI-2110568|ensemblmetazoa:FBpp0087300 psi-mi:p41073-1(display_long)|uniprotkb:Pep(gene name)|psi-mi:Pep(display_short)|uniprotkb:CG6143(orf name) psi-mi:q7k4g8_drome(display_long)|uniprotkb:anon-WO0140519.201(gene name)|psi-mi:anon-WO0140519.201(display_short)|uniprotkb:Dmel\CG12391(gene name synonym)|uniprotkb:CG12391(orf name)|uniprotkb:Dmel_CG12391(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110571|imex:IM-9552-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-522331(pep_drome)|ensemblmetazoa:FBgn0004401(gene)|ensemblmetazoa:FBtr0075199(transcript) refseq:NP_610639.1|flybase:FBgn0033581|ensemblmetazoa:FBgn0033581(gene)|ensemblmetazoa:FBtr0088205(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR012934(Zinc finger, AD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:29/JZMsZ78Uyh3MQGEfFkmct0S87227 rogid:481v188DLsjnGu/MN39IrScdLfE7227 intact-crc:1929EF1F1C354C93|rigid:U+ceNOl7oAKTeZIuGuYbF2HWEOI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P54362 uniprotkb:Q9VTG0 intact:EBI-115159|uniprotkb:O16015|uniprotkb:O45031|uniprotkb:Q9VY96|ensemblmetazoa:FBpp0073673 intact:EBI-196087|uniprotkb:Q8SZT3|ensemblmetazoa:FBpp0290653|ensemblmetazoa:FBpp0304951 psi-mi:ap3d_drome(display_long)|uniprotkb:Delta adaptin subunit of AP-3(gene name synonym)|uniprotkb:Garnet protein(gene name synonym)|uniprotkb:g(gene name)|psi-mi:g(display_short)|uniprotkb:CG10986(orf name) psi-mi:q9vtg0_drome(display_long)|uniprotkb:NaPi-III(gene name)|psi-mi:NaPi-III(display_short)|uniprotkb:CG7628-RA(gene name synonym)|uniprotkb:CR32078(gene name synonym)|uniprotkb:Dmel\CG42575(gene name synonym)|uniprotkb:Dromel_CG7628_FBtr0076213_mORF(gene name synonym)|uniprotkb:dPit(gene name synonym)|uniprotkb:Dmel_CG42575(orf name)|uniprotkb:CG42575(orf name)|uniprotkb:CG7628(orf name)|uniprotkb:dPiT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110563|imex:IM-9552-558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524785.2|flybase:FBgn0001087|ensemblmetazoa:FBgn0001087(gene)|ensemblmetazoa:FBtr0073842(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006726"(eye pigment biosynthetic process)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0008055"(ocellus pigment biosynthetic process)|go:"GO:0008057"(eye pigment granule organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010008"(endosome membrane)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0046907"(intracellular transport)|go:"GO:0048072"(compound eye pigmentation)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0060967"(negative regulation of gene silencing by RNA)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit) refseq:NP_648441.1|flybase:FBgn0260795|refseq:NP_001261704.1|ensemblmetazoa:FBgn0260795(gene)|ensemblmetazoa:FBtr0301438(transcript)|ensemblmetazoa:FBtr0332705(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044341"(sodium-dependent phosphate transport)|interpro:IPR001204(Phosphate transporter)|reactome:R-DME-427652 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:AOgtp76e3fBGIMGDs90N/S3YSRo7227 rogid:0pm8tDX+fi74FX9P0KEpd9xvtrQ7227 intact-crc:EC5D0E0F639C53F9|rigid:DIlVLUelNO2X6EJpdYyCoisEYi8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23380 uniprotkb:Q8T0T9 intact:EBI-185634|uniprotkb:A4UZ55|uniprotkb:Q0E9N6|uniprotkb:Q53XD4|uniprotkb:Q9V9D2|intact:EBI-3405892|ensemblmetazoa:FBpp0085483|ensemblmetazoa:FBpp0085484|ensemblmetazoa:FBpp0085485|ensemblmetazoa:FBpp0085486 intact:EBI-2110469|uniprotkb:Q9W0B4|ensemblmetazoa:FBpp0072644|ensemblmetazoa:FBpp0312183 psi-mi:vatl_drome(display_long)|uniprotkb:Vha16-1(gene name)|psi-mi:Vha16-1(display_short)|uniprotkb:VHA(gene name synonym)|uniprotkb:CG3161(orf name)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)|uniprotkb:Ductin(gene name synonym)|uniprotkb:Vha16(gene name synonym)|uniprotkb:Vacuolar H+ ATPase subunit 16-1(gene name synonym) psi-mi:q8t0t9_drome(display_long)|uniprotkb:CG13920(orf name)|uniprotkb:"BEST:CK00246"(gene name)|psi-mi:"BEST:CK00246"(display_short)|uniprotkb:CK00246(gene name synonym)|uniprotkb:Dmel\CG13920(gene name synonym)|uniprotkb:Dmel_CG13920(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110586|imex:IM-9552-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476801.1|refseq:NP_724474.1|refseq:NP_724475.1|refseq:NP_724476.1|flybase:FBgn0262736|dip:DIP-19390N|ensemblmetazoa:FBgn0262736(gene)|ensemblmetazoa:FBtr0086150(transcript)|ensemblmetazoa:FBtr0086151(transcript)|ensemblmetazoa:FBtr0086152(transcript)|ensemblmetazoa:FBtr0086153(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0033227"(dsRNA transport)|go:"GO:0045169"(fusome)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|reactome:R-DME-1222556|reactome:R-DME-6798695|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712 refseq:NP_647639.1|flybase:FBgn0025712|refseq:NP_001286902.1|ensemblmetazoa:FBgn0025712(gene)|ensemblmetazoa:FBtr0072761(transcript)|ensemblmetazoa:FBtr0346593(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|interpro:IPR029693|interpro:IPR032808|interpro:IPR040399 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uxgicWAlJCbsWVC4WNdmaEtY1Ck7227 rogid:y2M41YJUeBWEfMKF3AdzZAtQNzc7227 intact-crc:695B0B3BDABD7F81|rigid:DAk+9BFJOCnhV5WmDAfecBJyVKk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXW3 uniprotkb:Q9VJK3 intact:EBI-166026|ensemblmetazoa:FBpp0073835|uniprotkb:Q960Y1 intact:EBI-164167|intact:EBI-1628898|ensemblmetazoa:FBpp0080429|ensemblmetazoa:FBpp0307468 psi-mi:q9vxw3_drome(display_long)|uniprotkb:Dmel\CG12608(gene name)|psi-mi:Dmel\CG12608(display_short)|uniprotkb:CG12608(orf name)|uniprotkb:Dmel_CG12608(orf name) psi-mi:q9vjk3_drome(display_long)|uniprotkb:"BcDNA:AT27976"(gene name)|psi-mi:"BcDNA:AT27976"(display_short)|uniprotkb:Dmel\CG5968(gene name synonym)|uniprotkb:CG5968(orf name)|uniprotkb:Dmel_CG5968(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110581|imex:IM-9552-560 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0074018(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|ensemblmetazoa:FBgn0030630(gene)|refseq:NP_573019.1|flybase:FBgn0030630 refseq:NP_609797.1|flybase:FBgn0032588|ensemblmetazoa:FBgn0032588(gene)|ensemblmetazoa:FBtr0335499(transcript)|interpro:IPR031957|ensemblmetazoa:FBtr0080872(transcript)|refseq:NP_001260505.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cnH75G6LB7REYv2Sa/ySy1JROho7227 rogid:k0aI1tai0/cf1CCXdZokQ3LUH4s7227 intact-crc:0C26895F8DCC54B5|rigid:dfbTr5/7UP53zyDKgmPYTKoHpnU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTL6 uniprotkb:A8DWJ8 intact:EBI-2108861|ensemblmetazoa:FBpp0075838|ensemblmetazoa:FBpp0303920 intact:EBI-2110591|ensemblmetazoa:FBpp0111562|ensemblmetazoa:FBpp0311529|ensemblmetazoa:FBpp0311530 psi-mi:q9vtl6_drome(display_long)|uniprotkb:Polr3H(gene name)|psi-mi:Polr3H(display_short)|uniprotkb:Dmel\CG7339(gene name synonym)|uniprotkb:lincRNA.S4825(gene name synonym)|uniprotkb:CG7339(orf name)|uniprotkb:Dmel_CG7339(orf name) psi-mi:a8dwj8_drome(display_long)|uniprotkb:CG15924(gene name synonym)|uniprotkb:CG3896(gene name synonym)|uniprotkb:Dmel\CG34399(gene name synonym)|uniprotkb:NOX-1(gene name synonym)|uniprotkb:Nox1(gene name synonym)|uniprotkb:dNox(gene name synonym)|uniprotkb:dnox(gene name synonym)|uniprotkb:CG34399(orf name)|uniprotkb:Dmel_CG34399(orf name)|uniprotkb:Nox(gene name)|psi-mi:Nox(display_short)|uniprotkb:DmNox(gene name synonym)|uniprotkb:NOX(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110596|imex:IM-9552-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648490.1|flybase:FBgn0036188|refseq:NP_001261720.1|ensemblmetazoa:FBgn0036188(gene)|ensemblmetazoa:FBtr0076107(transcript)|ensemblmetazoa:FBtr0331530(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013238(RNA polymerase III, subunit Rpc25)|interpro:IPR036898|reactome:R-DME-76061|reactome:R-DME-76066 refseq:NP_001097336.1|flybase:FBgn0085428|refseq:NP_001286486.1|refseq:NP_611116.2|ensemblmetazoa:FBgn0085428(gene)|ensemblmetazoa:FBtr0112650(transcript)|ensemblmetazoa:FBtr0345378(transcript)|ensemblmetazoa:FBtr0345379(transcript)|go:"GO:0000293"(ferric-chelate reductase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0030728"(ovulation)|go:"GO:0033215"(reductive iron assimilation)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR039261|reactome:R-DME-3299685 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fbYiEsrBL8ujtAVTPVQXPeAMRms7227 rogid:OPOA3WhtQSW99FvRFPTsb5G5rTI7227 intact-crc:E991B49A7085E50F|rigid:LhjvEbIGqcqVejO+EIoBkHqCdUA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VC48 uniprotkb:P02572 intact:EBI-146422|ensemblmetazoa:FBpp0084120 intact:EBI-110368|uniprotkb:Q24228|uniprotkb:Q540X3|uniprotkb:Q9V9J4|ensemblmetazoa:FBpp0085365 psi-mi:q9vc48_drome(display_long)|uniprotkb:MAP1A(gene name)|psi-mi:MAP1A(display_short)|uniprotkb:Dmel\CG13630(gene name synonym)|uniprotkb:CG13630(orf name)|uniprotkb:Dmel_CG13630(orf name) psi-mi:act2_drome(display_long)|uniprotkb:Act42A(gene name)|psi-mi:Act42A(display_short)|uniprotkb:CG12051(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110601|imex:IM-9552-562 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651281.1|flybase:FBgn0039219|ensemblmetazoa:FBgn0039219(gene)|ensemblmetazoa:FBtr0084745(transcript)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|interpro:IPR031615|interpro:IPR036005 refseq:NP_523625.1|flybase:FBgn0000043|dip:DIP-20355N|ensemblmetazoa:FBgn0000043(gene)|ensemblmetazoa:FBtr0086029(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0035060"(brahma complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UzAvHipMYWyPLdWM0FO6LNTL8k47227 rogid:YeeXgsuRY2BQ3DVxG7MuVmol+bo7227 intact-crc:7429CDF3FFC9F00D|rigid:aHVQanNulBpnGhO+ShruFp8dHhs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8INE8 uniprotkb:Q9V426 intact:EBI-2110606|ensemblmetazoa:FBpp0082589 intact:EBI-82525|ensemblmetazoa:FBpp0080277|ensemblmetazoa:FBpp0080278|ensemblmetazoa:FBpp0080279|ensemblmetazoa:FBpp0080280|intact:EBI-3405793 psi-mi:q8ine8_drome(display_long)|uniprotkb:CG6563(orf name)|uniprotkb:Art3(gene name)|psi-mi:Art3(display_short)|uniprotkb:DART3(gene name synonym)|uniprotkb:Dmel\CG6563(gene name synonym)|uniprotkb:Dmel_CG6563(orf name) psi-mi:q9v426_drome(display_long)|uniprotkb:vig(gene name)|psi-mi:vig(display_short)|uniprotkb:Dmel_CG4170(orf name)|uniprotkb:"BG:DS00929.13"(gene name synonym)|uniprotkb:Dmel\CG4170(gene name synonym)|uniprotkb:"EP(2)0812"(gene name synonym)|uniprotkb:VIG(gene name synonym)|uniprotkb:Vig(gene name synonym)|uniprotkb:CG4170(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110611|imex:IM-9552-234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731984.1|flybase:FBgn0038306|ensemblmetazoa:FBgn0038306(gene)|ensemblmetazoa:FBtr0083135(transcript)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236 ensemblmetazoa:FBgn0024183(gene)|ensemblmetazoa:FBtr0080718(transcript)|ensemblmetazoa:FBtr0080719(transcript)|ensemblmetazoa:FBtr0080720(transcript)|ensemblmetazoa:FBtr0080721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR039764|reactome:R-DME-114608|refseq:NP_523572.1|refseq:NP_723896.1|refseq:NP_723897.1|refseq:NP_723898.1|flybase:FBgn0024183 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:e/HX67VxNe4NGajc87x7xktQslk7227 rogid:di+ekbJKilqKbXC1f0Pa4pdwubs7227 intact-crc:76D121C47931C86C|rigid:DNd73eDTmQjA+RE1Dl56kjxZm18 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P84249 uniprotkb:O46342 intact:EBI-120797|uniprotkb:A4V466|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q9V3W4 intact:EBI-2110619|uniprotkb:Q9VN43|ensemblmetazoa:FBpp0078499 psi-mi:h33_drome(display_long)|uniprotkb:His3.3A(gene name)|psi-mi:His3.3A(display_short)|uniprotkb:CG5825(orf name)|uniprotkb:His3.3B(gene name)|psi-mi:His3.3B(display_short)|uniprotkb:CG8989(orf name)|uniprotkb:H3.A/B(gene name synonym)|uniprotkb:H3.3Q(gene name synonym) psi-mi:o46342_drome(display_long)|uniprotkb:CG1058(orf name)|uniprotkb:dGNaC1(gene name synonym)|uniprotkb:rpk(gene name)|psi-mi:rpk(display_short)|uniprotkb:Dmel\CG1058(gene name synonym)|uniprotkb:GNaC1(gene name synonym)|uniprotkb:RPK(gene name synonym)|uniprotkb:ppk2(gene name synonym)|uniprotkb:Dmel_CG1058(orf name)|uniprotkb:Rpk(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110616|imex:IM-9552-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0006334"(nucleosome assembly)|refseq:NP_511095.1|refseq:NP_523479.1|refseq:NP_727314.1|refseq:NP_788892.1|flybase:FBgn0014857|flybase:FBgn0004828|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|go:"GO:0031492"(nucleosomal DNA binding)|reactome:R-DME-201722|reactome:R-DME-212300|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-427359|reactome:R-DME-427413|reactome:R-DME-5578749|reactome:R-DME-73777|reactome:R-DME-8936459|reactome:R-DME-983231|refseq:NP_001259374.1|refseq:NP_001260082.1|refseq:NP_723056.2|mint:MINT-840146 refseq:NP_524225.1|flybase:FBgn0022981|ensemblmetazoa:FBgn0022981(gene)|ensemblmetazoa:FBtr0078859(transcript)|go:"GO:0005272"(sodium channel activity)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0050975"(sensory perception of touch)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR020903 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I7227 rogid:x46zWQWEzCbBsXdVix1EhnC0Hg87227 intact-crc:F0CB6FE59102473C|rigid:EyZWjQXDbZtQ2okPBEKQbDmhklI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VZF4 uniprotkb:Q24337 intact:EBI-138334|intact:EBI-1628008|uniprotkb:A4V1G6|ensemblmetazoa:FBpp0073101|ensemblmetazoa:FBpp0073102|ensemblmetazoa:FBpp0073103 intact:EBI-169459|intact:EBI-1631667|uniprotkb:A4V463|uniprotkb:Q9W3B1|ensemblmetazoa:FBpp0071209|ensemblmetazoa:FBpp0071210|ensemblmetazoa:FBpp0301768|ensemblmetazoa:FBpp0305781|ensemblmetazoa:FBpp0305782 psi-mi:fbxw7_drome(display_long)|uniprotkb:ago(gene name)|psi-mi:ago(display_short)|uniprotkb:CG15010(orf name)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)|uniprotkb:Protein archipelago(gene name synonym) psi-mi:er_drome(display_long)|uniprotkb:"e(r)"(gene name)|psi-mi:"e(r)"(display_short)|uniprotkb:CG1871(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110626|imex:IM-9552-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|ensemblmetazoa:FBtr0073246(transcript)|ensemblmetazoa:FBtr0073247(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007419"(ventral cord development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030332"(cyclin binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060438"(trachea development)|go:"GO:0071456"(cellular response to hypoxia)|ensemblmetazoa:FBgn0041171(gene)|ensemblmetazoa:FBtr0073245(transcript)|refseq:NP_523922.1|refseq:NP_728964.1|refseq:NP_728965.1|flybase:FBgn0041171|dip:DIP-32477N ensemblmetazoa:FBgn0011586(gene)|ensemblmetazoa:FBtr0071266(transcript)|ensemblmetazoa:FBtr0071267(transcript)|ensemblmetazoa:FBtr0310067(transcript)|ensemblmetazoa:FBtr0333604(transcript)|ensemblmetazoa:FBtr0333605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007049"(cell cycle)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|refseq:NP_524662.1|refseq:NP_727293.1|flybase:FBgn0011586|refseq:NP_001259363.1|refseq:NP_001259364.1|refseq:NP_001259365.1|dip:DIP-19260N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:FVPUJUP1NZ/drDu6C4uA3VDNv307227 rogid:f4fk70qMBG+f0rMJe53JbAF8Lhg7227 intact-crc:D5032F8FADAC201B|rigid:tJqA2ffFSjj+Uf4K/eSZfPQc9to false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W429 uniprotkb:Q8MZ50 intact:EBI-2110638|uniprotkb:Q5BIK7|ensemblmetazoa:FBpp0070839|ensemblmetazoa:FBpp0070840 intact:EBI-2110634 psi-mi:s35b4_drome(display_long)|uniprotkb:Efr(gene name)|psi-mi:Efr(display_short)|uniprotkb:ER GDP-fucose transporter(gene name synonym)|uniprotkb:Solute carrier family 35 member B4 homolog(gene name synonym)|uniprotkb:CG3774(orf name) psi-mi:q8mz50_drome(display_long)|uniprotkb:CG3260(orf name)|uniprotkb:Zfrp8(gene name)|psi-mi:Zfrp8(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110631|imex:IM-9552-564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572299.1|refseq:NP_727071.1|flybase:FBgn0029849|ensemblmetazoa:FBgn0029849(gene)|ensemblmetazoa:FBtr0070874(transcript)|ensemblmetazoa:FBtr0070875(transcript)|go:"GO:0005457"(GDP-fucose transmembrane transporter activity)|go:"GO:0005462"(UDP-N-acetylglucosamine transmembrane transporter activity)|go:"GO:0005464"(UDP-xylose transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015782"(CMP-N-acetylneuraminate transmembrane transport)|go:"GO:0015783"(GDP-fucose transmembrane transport)|go:"GO:0015786"(UDP-glucose transmembrane transport)|go:"GO:0015787"(UDP-glucuronic acid transmembrane transport)|go:"GO:0015790"(UDP-xylose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0036066"(protein O-linked fucosylation)|go:"GO:0036084"(GDP-fucose import into endoplasmic reticulum lumen)|go:"GO:1990569"(UDP-N-acetylglucosamine transmembrane transport)|go:"GO:1990570"(GDP-mannose transmembrane transport)|interpro:IPR013657(UAA transporter)|reactome:R-DME-727802 flybase:FBgn0021875|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048477"(oogenesis)|go:"GO:2000765"(regulation of cytoplasmic translation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007320(Programmed cell death protein 2, C-terminal) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xrfR6WUy/ANw3NUVQ2XMXaiN5ec7227 rogid:cc9ZOs/Fg6WGy7yRJ2qJcvbHn3Y7227 intact-crc:713867D3F5DE37B9|rigid:7Uu3Z5t30a7KzmDt+38aPbUhOeE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9U8D0 uniprotkb:Q9VD37 intact:EBI-2110658 intact:EBI-2110665|ensemblmetazoa:FBpp0111522|ensemblmetazoa:FBpp0300318|ensemblmetazoa:FBpp0311485 psi-mi:q9u8d0_drome(display_long)|uniprotkb:CG5796(orf name)|uniprotkb:Ppox(gene name)|psi-mi:Ppox(display_short) psi-mi:q9vd37_drome(display_long)|uniprotkb:CG13859(gene name)|psi-mi:CG13859(display_short)|uniprotkb:CG13858(gene name synonym)|uniprotkb:CG13860(gene name synonym)|uniprotkb:CG13861(gene name synonym)|uniprotkb:Dmel\CG34377(gene name synonym)|uniprotkb:CG34377(orf name)|uniprotkb:Dmel_CG34377(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110662|imex:IM-9552-238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0020018|go:"GO:0004729"(oxygen-dependent protoporphyrinogen oxidase activity)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031304"(intrinsic component of mitochondrial inner membrane)|interpro:IPR002937(Amine oxidase)|interpro:IPR004572(Protoporphyrinogen oxidase)|interpro:IPR036188 refseq:NP_651018.2|flybase:FBgn0263117|refseq:NP_001287461.1|refseq:NP_001247236.1|ensemblmetazoa:FBgn0263117(gene)|ensemblmetazoa:FBtr0112610(transcript)|ensemblmetazoa:FBtr0307884(transcript)|ensemblmetazoa:FBtr0345325(transcript)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:3WKb07oVikeuR5rRs6jAl6K0MBU7227 rogid:aB0z9hWq7azfPNuTmCnaKluERlE7227 intact-crc:88456DC7D71C43FB|rigid:z+OOgSbLFBBPP5Ri8qzB6pasTHQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q86B83 uniprotkb:Q9V6B9 intact:EBI-114500|ensemblmetazoa:FBpp0083681 intact:EBI-179307|ensemblmetazoa:FBpp0087063 psi-mi:q86b83_drome(display_long)|uniprotkb:CG5340(gene name)|psi-mi:CG5340(display_short)|uniprotkb:CG33099-RA(gene name synonym)|uniprotkb:Dmel\CG33099(gene name synonym)|uniprotkb:CG33099(orf name)|uniprotkb:Dmel_CG33099(orf name) psi-mi:nup54_drome(display_long)|uniprotkb:CG8831(orf name)|uniprotkb:Nup54(gene name)|psi-mi:Nup54(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110644|imex:IM-9552-236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788714.1|flybase:FBgn0053099|ensemblmetazoa:FBgn0053099(gene)|ensemblmetazoa:FBtr0084288(transcript)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR026992|interpro:IPR027443 refseq:NP_610783.1|flybase:FBgn0033737|dip:DIP-19285N|ensemblmetazoa:FBgn0033737(gene)|ensemblmetazoa:FBtr0087952(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q9V6B9|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:SLr+G8ZKbHOT9vQ+BubJD/Rv3uo7227 rogid:0RSPWkJnRddLDMAOCRvpHWcUlSo7227 intact-crc:1551C7EFDAA1B946|rigid:uTIlH1QlRDigUXU3U3z5yh5Fcrs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23257 uniprotkb:Q7JXF7 intact:EBI-178952|uniprotkb:Q9VQJ5|ensemblmetazoa:FBpp0077326 intact:EBI-225746|intact:EBI-2110652|ensemblmetazoa:FBpp0087519 psi-mi:tbg1_drome(display_long)|uniprotkb:gammaTub23C(gene name)|psi-mi:gammaTub23C(display_short)|uniprotkb:Tub23C(gene name synonym)|uniprotkb:TubG(gene name synonym)|uniprotkb:TubG1(gene name synonym)|uniprotkb:CG3157(orf name)|uniprotkb:TubG23C(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym) psi-mi:seele_drome(display_long)|uniprotkb:sel(gene name)|psi-mi:sel(display_short)|uniprotkb:CG12918(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110649|imex:IM-9552-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476804.1|flybase:FBgn0260639|ensemblmetazoa:FBgn0260639(gene)|ensemblmetazoa:FBtr0077641(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103 refseq:NP_610547.1|flybase:FBgn0263260|ensemblmetazoa:FBgn0263260(gene)|ensemblmetazoa:FBtr0088433(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007311"(maternal specification of dorsal/ventral axis, oocyte, germ-line encoded)|go:"GO:0009951"(polarity specification of dorsal/ventral axis)|go:"GO:0012505"(endomembrane system)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070613"(regulation of protein processing)|interpro:IPR021852|interpro:IPR042415 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:v8VA+z+B2QYczBYdLotcT1Rptso7227 rogid:iw6HkOiFYTsJD92GFlfTNuYXm9s7227 intact-crc:384775B678ACEDFA|rigid:uHMI9S19qkPUq3tCfEPkC8hnCOA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWS5 uniprotkb:Q9VJJ0 intact:EBI-2110671|ensemblmetazoa:FBpp0074389 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:q9vws5_drome(display_long)|uniprotkb:Dmel\CG15040(gene name)|psi-mi:Dmel\CG15040(display_short)|uniprotkb:CG15040(orf name)|uniprotkb:Dmel_CG15040(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110675|imex:IM-9552-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573311.1|flybase:FBgn0030940|ensemblmetazoa:FBgn0030940(gene)|ensemblmetazoa:FBtr0074618(transcript) refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:SywCyft1ZgSH0G+x/7ATk3smMpE7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:6CE790A596A7CB39|rigid:2T2ZEofXndLdC0638pHvLayqYgA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q27889 uniprotkb:Q9VXP4 intact:EBI-132663|uniprotkb:Q26248|uniprotkb:Q9VXF2|ensemblmetazoa:FBpp0294044|ensemblmetazoa:FBpp0301546|ensemblmetazoa:FBpp0074069 intact:EBI-2110680|uniprotkb:A4V4G6|uniprotkb:O96644|ensemblmetazoa:FBpp0073975|ensemblmetazoa:FBpp0073976 psi-mi:pp2b2_drome(display_long)|uniprotkb:Pp2B-14D(gene name)|psi-mi:Pp2B-14D(display_short)|uniprotkb:CG9842(orf name)|uniprotkb:Calmodulin-dependent calcineurin A2 subunit(gene name synonym) psi-mi:pa1b2_drome(display_long)|uniprotkb:CG8962(orf name)|uniprotkb:Paf-AHalpha(gene name)|psi-mi:Paf-AHalpha(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110685|imex:IM-9552-240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245715.1|refseq:NP_001245716.1|refseq:NP_523373.2|flybase:FBgn0011826|ensemblmetazoa:FBgn0011826(gene)|ensemblmetazoa:FBtr0074294(transcript)|ensemblmetazoa:FBtr0305593(transcript)|ensemblmetazoa:FBtr0309793(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0030431"(sleep)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035220"(wing disc development)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|reactome:R-DME-2025928|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-5607763|go:"GO:0046872"(metal ion binding)|dip:DIP-17529N refseq:NP_525089.2|refseq:NP_727895.1|flybase:FBgn0025809|ensemblmetazoa:FBgn0025809(gene)|ensemblmetazoa:FBtr0074190(transcript)|ensemblmetazoa:FBtr0074191(transcript)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|reactome:R-DME-6798695|reactome:R-DME-6807505 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:APK5Eysj8I52ZqWvwHe1d9pwWNo7227 rogid:ybj+PsSU7nn49/uGhm+Sep1wDb87227 intact-crc:4CDA5C620C453DDD|rigid:yCf7qK4R+117Vps6lHSa8pAAELA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95SU6 uniprotkb:Q9VPT2 intact:EBI-2110693 intact:EBI-2110697|ensemblmetazoa:FBpp0077672|ensemblmetazoa:FBpp0304042 psi-mi:q95su6_drome(display_long)|uniprotkb:CG4970(orf name) psi-mi:q9vpt2_drome(display_long)|uniprotkb:CG3544(orf name)|uniprotkb:Dmel_CG3544(orf name)|uniprotkb:Dmel\CG3544(gene name)|psi-mi:Dmel\CG3544(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110690|imex:IM-9552-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0032364|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|interpro:IPR025254 refseq:NP_608543.1|flybase:FBgn0031279|refseq:NP_001259842.1|ensemblmetazoa:FBgn0031279(gene)|ensemblmetazoa:FBtr0078007(transcript)|ensemblmetazoa:FBtr0331652(transcript)|go:"GO:0004856"(xylulokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005997"(xylulose metabolic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|go:"GO:0042732"(D-xylose metabolic process)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR018484|interpro:IPR018485|interpro:IPR042024|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o7N+HDrMnZ37xFuAxPTPBtBREMY7227 rogid:ZdwiYw5LnpwYSU3zn0fML/MJz8c7227 intact-crc:BF3F11A566472CD6|rigid:Dvi8DY24Ggs78rSHRhvGwtjjZkE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K4E0 uniprotkb:Q8SZ99 intact:EBI-458912|ensemblmetazoa:FBpp0085412|intact:EBI-2110705 intact:EBI-2110710 psi-mi:q7k4e0_drome(display_long)|uniprotkb:CG12183(gene name)|psi-mi:CG12183(display_short)|uniprotkb:CG10412(gene name synonym)|uniprotkb:CG10416(gene name synonym)|uniprotkb:Dmel\CG30440(gene name synonym)|uniprotkb:CG30440(orf name)|uniprotkb:Dmel_CG30440(orf name) psi-mi:q8sz99_drome(display_long)|uniprotkb:CG9117(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110702|imex:IM-9552-242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0050440(gene)|ensemblmetazoa:FBtr0086076(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-DME-193634|reactome:R-DME-193648|reactome:R-DME-416482|reactome:R-DME-8980692|reactome:R-DME-9013148|reactome:R-DME-9013149|reactome:R-DME-9013404|refseq:NP_610172.1|flybase:FBgn0050440 flybase:FBgn0031766|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR036866|interpro:IPR039344 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:EuNGJt3c4PY3tiklAHyeE+UCGr47227 rogid:NZXKCSS7gl1J1eQF6FC79ZMoB0g7227 intact-crc:A0218BFA05422C10|rigid:Rw6uHpeajTfUPiTwrERWnvASzrA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W3Y3 uniprotkb:Q9VD52 intact:EBI-2110492|ensemblmetazoa:FBpp0070953 intact:EBI-2110719|ensemblmetazoa:FBpp0083581 psi-mi:q9w3y3_drome(display_long)|uniprotkb:Dmel\CG3226(gene name)|psi-mi:Dmel\CG3226(display_short)|uniprotkb:Q9W3Y3(gene name synonym)|uniprotkb:CG3226(orf name)|uniprotkb:Dmel_CG3226(orf name) psi-mi:q9vd52_drome(display_long)|uniprotkb:CDC40(gene name)|psi-mi:CDC40(display_short)|uniprotkb:Dmel\CG6015(gene name synonym)|uniprotkb:prp17(gene name synonym)|uniprotkb:CG6015(orf name)|uniprotkb:Dmel_CG6015(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110716|imex:IM-9552-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572332.1|flybase:FBgn0029882|ensemblmetazoa:FBgn0029882(gene)|ensemblmetazoa:FBtr0070993(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0015631"(tubulin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044548"(S100 protein binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893 refseq:NP_651005.1|flybase:FBgn0038927|ensemblmetazoa:FBgn0038927(gene)|ensemblmetazoa:FBtr0084183(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR032847|interpro:IPR036322|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:btXDxLSH1VBNdWKeHqDfbD13yxI7227 rogid:1kNG8/vfn4oVQ+RxJjoBjBVb7+g7227 intact-crc:CCCC7E5F6BA293AC|rigid:b5kzTY8BJr9NZ3m0yuOOab+IkvI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q76NR6 uniprotkb:A1ZA18 intact:EBI-2110733|ensemblmetazoa:FBpp0073422 intact:EBI-108503|intact:EBI-2110743|ensemblmetazoa:FBpp0086490 psi-mi:q76nr6_drome(display_long)|uniprotkb:CG1803(orf name)|uniprotkb:regucalcin(gene name)|psi-mi:regucalcin(display_short)|uniprotkb:Dmel\CG1803(gene name synonym)|uniprotkb:Regucalcin(gene name synonym)|uniprotkb:T1(gene name synonym)|uniprotkb:Dmel_CG1803(orf name) psi-mi:a1za18_drome(display_long)|uniprotkb:Khc-73(gene name)|psi-mi:Khc-73(display_short)|uniprotkb:B(gene name synonym)|uniprotkb:DmKIN73(gene name synonym)|uniprotkb:DmKin73(gene name synonym)|uniprotkb:DmKlp73(gene name synonym)|uniprotkb:Dmel\CG8183(gene name synonym)|uniprotkb:KIF13A(gene name synonym)|uniprotkb:KLP73(gene name synonym)|uniprotkb:Khc73(gene name synonym)|uniprotkb:Kin73(gene name synonym)|uniprotkb:Kinesin-73(gene name synonym)|uniprotkb:"anon-EST:fe3C9"(gene name synonym)|uniprotkb:khc-73(gene name synonym)|uniprotkb:CG8183(orf name)|uniprotkb:Dmel_CG8183(orf name)|uniprotkb:KHC-73(gene name synonym)|uniprotkb:KIF 13A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110748|imex:IM-9552-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727588.2|flybase:FBgn0030362|ensemblmetazoa:FBgn0030362(gene)|ensemblmetazoa:FBtr0073578(transcript)|go:"GO:0004341"(gluconolactonase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019853"(L-ascorbic acid biosynthetic process)|go:"GO:0032504"(multicellular organism reproduction)|interpro:IPR005511("Senescence marker protein-30 (SMP-30)")|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013658(SMP-30/Gluconolaconase/LRE-like region) refseq:NP_609201.3|flybase:FBgn0019968|ensemblmetazoa:FBgn0019968(gene)|ensemblmetazoa:FBtr0087357(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0008017"(microtubule binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1990939"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR032923|interpro:IPR036859|interpro:IPR036961 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WuEdkOhV7Abujsw5IRgxRXMTveg7227 rogid:mcJsmPo0HBaMx4MOdnOHT1h5Pzg7227 intact-crc:67B646997ED76DF9|rigid:HxnVPzAyzDJGzFw4zd3X64anGb0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z8Y4 uniprotkb:Q9VSH7 intact:EBI-86675|ensemblmetazoa:FBpp0087067|intact:EBI-2110724 intact:EBI-134054|ensemblmetazoa:FBpp0076328 psi-mi:a1z8y4_drome(display_long)|uniprotkb:Dmel\CG13155(gene name)|psi-mi:Dmel\CG13155(display_short)|uniprotkb:CG13155(orf name)|uniprotkb:Dmel_CG13155(orf name) psi-mi:q9vsh7_drome(display_long)|uniprotkb:Cpr66Cb(gene name)|psi-mi:Cpr66Cb(display_short)|uniprotkb:DmelCpr66Cb(gene name synonym)|uniprotkb:Dmel\CG7076(gene name synonym)|uniprotkb:Dmel_CG7076(orf name)|uniprotkb:CG7076(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110728|imex:IM-9552-244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610770.1|flybase:FBgn0033723|ensemblmetazoa:FBgn0033723(gene)|ensemblmetazoa:FBtr0087956(transcript) refseq:NP_648209.1|flybase:FBgn0035875|ensemblmetazoa:FBgn0035875(gene)|ensemblmetazoa:FBtr0076601(transcript)|go:"GO:0008010"(structural constituent of chitin-based larval cuticle)|go:"GO:0031012"(extracellular matrix)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0062129"(chitin-based extracellular matrix)|interpro:IPR000618(Insect cuticle protein)|interpro:IPR031311 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:iB862TmRkkaa0ivC3lwvhfgQ0aQ7227 rogid:Aq8fEeKE/UYPM9vICq4/NZ6IVBU7227 intact-crc:46F41DC460742602|rigid:6oOo0fnjuNOWd0ggwS7gL2Sr+/8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VKG8 uniprotkb:Q76NR6 intact:EBI-125158|ensemblmetazoa:FBpp0079831|ensemblmetazoa:FBpp0079832 intact:EBI-2110733|ensemblmetazoa:FBpp0073422 psi-mi:q9vkg8_drome(display_long)|uniprotkb:Dlg5(gene name)|psi-mi:Dlg5(display_short)|uniprotkb:DLG5(gene name synonym)|uniprotkb:Dmel\CG6509(gene name synonym)|uniprotkb:LD32687(gene name synonym)|uniprotkb:dlg5(gene name synonym)|uniprotkb:Dmel_CG6509(orf name)|uniprotkb:CG6509(orf name) psi-mi:q76nr6_drome(display_long)|uniprotkb:CG1803(orf name)|uniprotkb:regucalcin(gene name)|psi-mi:regucalcin(display_short)|uniprotkb:Dmel\CG1803(gene name synonym)|uniprotkb:Regucalcin(gene name synonym)|uniprotkb:T1(gene name synonym)|uniprotkb:Dmel_CG1803(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110738|imex:IM-9552-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609505.1|refseq:NP_723672.1|flybase:FBgn0032363|reactome:R-DME-9013424|ensemblmetazoa:FBgn0032363(gene)|ensemblmetazoa:FBtr0080246(transcript)|ensemblmetazoa:FBtr0080247(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045177"(apical part of cell)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035537|interpro:IPR036034|reactome:R-DME-9013420 refseq:NP_727588.2|flybase:FBgn0030362|ensemblmetazoa:FBgn0030362(gene)|ensemblmetazoa:FBtr0073578(transcript)|go:"GO:0004341"(gluconolactonase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019853"(L-ascorbic acid biosynthetic process)|go:"GO:0032504"(multicellular organism reproduction)|interpro:IPR005511("Senescence marker protein-30 (SMP-30)")|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013658(SMP-30/Gluconolaconase/LRE-like region) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yv4duvPkYQHbG9VX4WqfyF5HD6M7227 rogid:WuEdkOhV7Abujsw5IRgxRXMTveg7227 intact-crc:BD1F5C7106998E19|rigid:S8+yOvca4FOl/dhcdtJOrT9cBwc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q961H1 uniprotkb:Q24141 intact:EBI-167433|ensemblmetazoa:FBpp0078276|ensemblmetazoa:FBpp0289963 intact:EBI-183986|ensemblmetazoa:FBpp0071675|ensemblmetazoa:FBpp0309743 psi-mi:q961h1_drome(display_long)|uniprotkb:kat-60L1(gene name)|psi-mi:kat-60L1(display_short)|uniprotkb:KATNA1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:Dmel_CG1193(orf name)|uniprotkb:DmCG1193(gene name synonym)|uniprotkb:Dmel\CG1193(gene name synonym)|uniprotkb:CG1193(orf name) psi-mi:sgo1_drome(display_long)|uniprotkb:mei-S332(gene name)|psi-mi:mei-S332(display_short)|uniprotkb:CG5303(orf name)|uniprotkb:Meiotic protein S332(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110772|imex:IM-9552-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0037375(gene)|ensemblmetazoa:FBtr0300739(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051013"(microtubule severing)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028596|interpro:IPR041569|ensemblmetazoa:FBtr0078627(transcript)|refseq:NP_001163524.1|refseq:NP_649586.1|flybase:FBgn0037375 refseq:NP_476634.1|flybase:FBgn0002715|refseq:NP_001286705.1|dip:DIP-17412N|ensemblmetazoa:FBgn0002715(gene)|ensemblmetazoa:FBtr0071761(transcript)|ensemblmetazoa:FBtr0342979(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR011515(Shugoshin, C-terminal)|interpro:IPR011516(Shugoshin, N-terminal) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:lL4YfmP/uaUcz1N2HW9VLWV804Y7227 rogid:Y7NZIBor9Nu7SCUO74sK3MHs2ww7227 intact-crc:B06C0873ECA43EDC|rigid:z9ZEZ4FvxhQQ9cGD52zNqgRWPac false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VD07 uniprotkb:Q8T492 intact:EBI-2110753|ensemblmetazoa:FBpp0083688 intact:EBI-2110761 psi-mi:q9vd07_drome(display_long)|uniprotkb:Dmel\CG12499(gene name)|psi-mi:Dmel\CG12499(display_short)|uniprotkb:CG12499(orf name)|uniprotkb:Dmel_CG12499(orf name) psi-mi:q8t492_drome(display_long)|uniprotkb:CG6083(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110758|imex:IM-9552-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651044.1|flybase:FBgn0038968|ensemblmetazoa:FBgn0038968(gene)|ensemblmetazoa:FBtr0084295(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|interpro:IPR021714|interpro:IPR032436|interpro:IPR039844 flybase:FBgn0036183|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005829"(cytosol)|go:"GO:0016319"(mushroom body development)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Hkg6TwFxwtKm9w3ByvzZF7/68KQ7227 rogid:yccoTiG32se2OQoFI+KA0k91FDQ7227 intact-crc:1672A498068B1C2E|rigid:oLx20t60iGkZKzkPgjvkSePRN0I false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VSY9 uniprotkb:Q9VXT5 intact:EBI-114491|ensemblmetazoa:FBpp0076232 intact:EBI-147143|uniprotkb:Q95RI4|ensemblmetazoa:FBpp0073887|ensemblmetazoa:FBpp0309306 psi-mi:q9vsy9_drome(display_long)|uniprotkb:CG3891(orf name)|uniprotkb:Nf-YA(gene name)|psi-mi:Nf-YA(display_short)|uniprotkb:Dmel\CG3891(gene name synonym)|uniprotkb:NF-YA(gene name synonym)|uniprotkb:dNF-YA(gene name synonym)|uniprotkb:Dmel_CG3891(orf name) psi-mi:c19l2_drome(display_long)|uniprotkb:CG9213(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110767|imex:IM-9552-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648313.1|flybase:FBgn0035993|ensemblmetazoa:FBgn0035993(gene)|ensemblmetazoa:FBtr0076504(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001289(CCAAT-binding transcription factor, subunit B) refseq:NP_001285277.1|refseq:NP_788910.1|flybase:FBgn0030655|ensemblmetazoa:FBgn0030655(gene)|ensemblmetazoa:FBtr0074071(transcript)|ensemblmetazoa:FBtr0340348(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR006767(Protein similar to CwfJ, C-terminal 2)|interpro:IPR006768(Protein similar to CwfJ, C-terminal 1)|interpro:IPR036265|interpro:IPR040194 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:n813f7Uj9Pw2iRGrdZ2nmNjupyI7227 rogid:i/bDZAgD8n0oucXqRbIQ4LjKakc7227 intact-crc:4474D2BD018A2BE2|rigid:ah+0hk1xZyu1VoE/03CrFvBSYXI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VPU8 uniprotkb:Q9VFN9 intact:EBI-104301|intact:EBI-2110795|uniprotkb:O02394|ensemblmetazoa:FBpp0077694 intact:EBI-160656|ensemblmetazoa:FBpp0082333|ensemblmetazoa:FBpp0306412 psi-mi:krr1_drome(display_long)|uniprotkb:dbe(gene name)|psi-mi:dbe(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Protein dribble(gene name synonym)|uniprotkb:dribble(gene name synonym)|uniprotkb:CG4258(orf name) psi-mi:q9vfn9_drome(display_long)|uniprotkb:dHYPK(gene name)|psi-mi:dHYPK(display_short)|uniprotkb:"BcDNA:RE55111"(gene name synonym)|uniprotkb:Dmel\CG9922(gene name synonym)|uniprotkb:"NEST:bs28g09"(gene name synonym)|uniprotkb:CG9922(orf name)|uniprotkb:Dmel_CG9922(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110799|imex:IM-9552-252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477240.1|flybase:FBgn0020305|ensemblmetazoa:FBgn0020305(gene)|ensemblmetazoa:FBtr0078030(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0032040"(small-subunit processome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|reactome:R-DME-6791226|interpro:IPR041174 refseq:NP_650329.1|flybase:FBgn0038196|ensemblmetazoa:FBgn0038196(gene)|ensemblmetazoa:FBtr0082870(transcript)|ensemblmetazoa:FBtr0334297(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|refseq:NP_001262556.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ZY43SYPaQzKTwwZhrxBcb7Uuffc7227 rogid:lQ8FZfj45OET5LZWaMGsRyomNg07227 intact-crc:84DD5983806DB2DA|rigid:YDCjJxjlkOII/516O6ieZ4LA010 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VTW0 uniprotkb:Q9VPS5 intact:EBI-114346|intact:EBI-1627495|ensemblmetazoa:FBpp0075741 intact:EBI-159512|intact:EBI-1631255|ensemblmetazoa:FBpp0077665|uniprotkb:Q53YH7|uniprotkb:Q961V0 psi-mi:q9vtw0_drome(display_long)|uniprotkb:Sms(gene name)|psi-mi:Sms(display_short)|uniprotkb:Dmel\CG4300(gene name synonym)|uniprotkb:anon-WO0118547.387(gene name synonym)|uniprotkb:dSms(gene name synonym)|uniprotkb:CG4300(orf name)|uniprotkb:Dmel_CG4300(orf name) psi-mi:ch60b_drome(display_long)|uniprotkb:Hsp60B(gene name)|psi-mi:Hsp60B(display_short)|uniprotkb:CG2830(orf name)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:CPN60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110777|imex:IM-9552-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_729798.1|flybase:FBgn0036272|ensemblmetazoa:FBgn0036272(gene)|ensemblmetazoa:FBtr0076009(transcript)|go:"GO:0006597"(spermine biosynthetic process)|go:"GO:0016768"(spermine synthase activity)|interpro:IPR001045(Spermine synthase)|interpro:IPR015576(Spermine synthase-related)|interpro:IPR029063|interpro:IPR030374|interpro:IPR035246|interpro:IPR037163 refseq:NP_524925.1|flybase:FBgn0011244|ensemblmetazoa:FBgn0011244(gene)|ensemblmetazoa:FBtr0078000(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051087"(chaperone binding)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|dip:DIP-17907N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9XVG1a47+uVpQlALaofjfq5ShFU7227 rogid:ugMgQCH0uIeTXrGDK9VGVaLFH1g7227 intact-crc:D9DC323905BE7E6C|rigid:NjGA571hKJRuuoD3Z3c5013aWNA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q963J0 uniprotkb:Q8MSI6 intact:EBI-2110788|ensemblmetazoa:FBpp0293151 intact:EBI-2110785|ensemblmetazoa:FBpp0302607 psi-mi:q963j0_drome(display_long)|uniprotkb:CG15899(orf name)|uniprotkb:Ca-alpha-1T(gene name synonym)|uniprotkb:Ca-alpha1T(gene name)|psi-mi:Ca-alpha1T(display_short)|uniprotkb:Caalpha1t(gene name synonym) psi-mi:q8msi6_drome(display_long)|uniprotkb:CG3713(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110782|imex:IM-9552-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264386|ensemblmetazoa:FBgn0264386(gene)|ensemblmetazoa:FBtr0304609(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0008332"(low voltage-gated calcium channel activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0043005"(neuron projection)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR005821(Ion transport)|interpro:IPR030154|interpro:IPR043203 flybase:FBgn0040343|ensemblmetazoa:FBgn0040343(gene)|ensemblmetazoa:FBtr0310459(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:qyJNuPPCaEoIs8MTYMTx3tiemVo7227 rogid:JLk/q1fn1Z/74rZVxRly87HQYhU7227 intact-crc:5738807D2FE349B3|rigid:juRoWERpz0awIZTZHHTnu8BDFPs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P10181 uniprotkb:P36958 intact:EBI-1628329|uniprotkb:Q9VBA7|uniprotkb:Q24487|uniprotkb:Q4V714|ensemblmetazoa:FBpp0084460|ensemblmetazoa:FBpp0084461 intact:EBI-167046|uniprotkb:Q9VFK8|ensemblmetazoa:FBpp0082384|ensemblmetazoa:FBpp0301701|ensemblmetazoa:FBpp0312065 psi-mi:rough_drome(display_long)|uniprotkb:ro(gene name)|psi-mi:ro(display_short)|uniprotkb:CG6348(orf name) psi-mi:rpb9_drome(display_long)|uniprotkb:RpII15(gene name)|psi-mi:RpII15(display_short)|uniprotkb:DNA-directed RNA polymerase II 15.1 kDa polypeptide(gene name synonym)|uniprotkb:CG3284(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110804|imex:IM-9552-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524521.1|refseq:NP_733173.1|flybase:FBgn0003267|ensemblmetazoa:FBgn0003267(gene)|ensemblmetazoa:FBtr0085090(transcript)|ensemblmetazoa:FBtr0085091(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007463"(R2/R5 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048054"(R2/R5 cell differentiation)|go:"GO:0050896"(response to stimulus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 refseq:NP_731898.1|flybase:FBgn0004855|refseq:NP_001287326.1|refseq:NP_001247099.1|ensemblmetazoa:FBgn0004855(gene)|ensemblmetazoa:FBtr0082925(transcript)|ensemblmetazoa:FBtr0309995(transcript)|ensemblmetazoa:FBtr0346348(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|reactome:R-DME-112382|reactome:R-DME-113418|reactome:R-DME-674695|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6796648|reactome:R-DME-6803529|reactome:R-DME-6807505|reactome:R-DME-72086|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72203|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-75955|reactome:R-DME-76042|reactome:R-DME-77075|reactome:R-DME-9018519 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:a6gi8AevSKISSRxd/P50oXGsmxc7227 rogid:K8+jkKBGdg6cYbB7VrHptQ59DRA7227 intact-crc:503BA6C22C8ABE33|rigid:QQhjj5hbccCSIQVa0ysoAcHT/rU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VKA2 uniprotkb:P40301 intact:EBI-133778|ensemblmetazoa:FBpp0079923 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:q9vka2_drome(display_long)|uniprotkb:Dmel\CG17217(gene name)|psi-mi:Dmel\CG17217(display_short)|uniprotkb:Dmel_CG17217(orf name)|uniprotkb:CG17217(orf name) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110809|imex:IM-9552-254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609555.1|flybase:FBgn0032419|ensemblmetazoa:FBgn0032419(gene)|ensemblmetazoa:FBtr0080341(transcript) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WY001j6RfO2/oLguuRLGrSFG50w7227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:4B08B4ECCBD82999|rigid:5XuX/XiP1UlXIyLjkdNFpWuLhJk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWC6 uniprotkb:Q7K2Y9 intact:EBI-133058|ensemblmetazoa:FBpp0074576|ensemblmetazoa:FBpp0074577|ensemblmetazoa:FBpp0311265 intact:EBI-157455|ensemblmetazoa:FBpp0086423|ensemblmetazoa:FBpp0300971|ensemblmetazoa:FBpp0300972|ensemblmetazoa:FBpp0309027|intact:EBI-2108428 psi-mi:q9vwc6_drome(display_long)|uniprotkb:Dmel\CG12701(gene name synonym)|uniprotkb:EP1344(gene name synonym)|uniprotkb:VFL(gene name synonym)|uniprotkb:Vfl(gene name synonym)|uniprotkb:ZLD(gene name synonym)|uniprotkb:Zelda(gene name synonym)|uniprotkb:Zld(gene name synonym)|uniprotkb:"l(1)G0225"(gene name synonym)|uniprotkb:"l(1)G0353"(gene name synonym)|uniprotkb:"l(1)G0427"(gene name synonym)|uniprotkb:zld(gene name)|psi-mi:zld(display_short)|uniprotkb:vfl(gene name synonym)|uniprotkb:vfl-RA(gene name synonym)|uniprotkb:Dmel_CG12701(orf name)|uniprotkb:CG12701(orf name) psi-mi:ntaq1_drome(display_long)|uniprotkb:CG8253(orf name)|uniprotkb:tun(gene name)|psi-mi:tun(display_short)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:Protein tungus(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110814|imex:IM-9552-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608356.1|refseq:NP_728304.1|flybase:FBgn0259789|refseq:NP_001285466.1|ensemblmetazoa:FBtr0074808(transcript)|ensemblmetazoa:FBtr0345014(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007349"(cellularization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensemblmetazoa:FBgn0259789(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0140587"(chromatin loop anchoring activity)|ensemblmetazoa:FBtr0074807(transcript)|go:"GO:2000543"(positive regulation of gastrulation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236 ensemblmetazoa:FBgn0034046(gene)|ensemblmetazoa:FBtr0087287(transcript)|ensemblmetazoa:FBtr0308814(transcript)|ensemblmetazoa:FBtr0308815(transcript)|ensemblmetazoa:FBtr0340013(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|refseq:NP_001246351.1|refseq:NP_001246352.1|refseq:NP_001286468.1|refseq:NP_611061.1|flybase:FBgn0034046 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Hd039uRVcbArEErhs8drFPAD1U07227 rogid:Est0CQKXm6fJTkv4cQGY2sCCpa87227 intact-crc:FDA69D915AFE5FDA|rigid:emwRTAefUMBofvricGQdrjqx/Vo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P26270 uniprotkb:Q9VQG0 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 intact:EBI-93950|uniprotkb:Q8SWS6|ensemblmetazoa:FBpp0077399|ensemblmetazoa:FBpp0307125 psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:q9vqg0_drome(display_long)|uniprotkb:CG2848(orf name)|uniprotkb:Dmel_CG2848(orf name)|uniprotkb:Tnpo-SR(gene name)|psi-mi:Tnpo-SR(display_short)|uniprotkb:Dmel\CG2848(gene name synonym)|uniprotkb:TNPO3(gene name synonym)|uniprotkb:Trn-SR(gene name synonym)|uniprotkb:"anon-EST:Posey294"(gene name synonym)|uniprotkb:dTRN-SR(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110819|imex:IM-9552-256 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_608708.2|flybase:FBgn0031456|ensemblmetazoa:FBgn0031456(gene)|ensemblmetazoa:FBtr0077715(transcript)|ensemblmetazoa:FBtr0335126(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001259961.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 rogid:2UfxMPbxdHXFDKaF8f+uejPH6Gk7227 intact-crc:129506ABD262C49F|rigid:ZuOeuRwKNRQ5y26PDoQEhOkJLUY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q04499 uniprotkb:Q9VCQ9 intact:EBI-197717|intact:EBI-197702|intact:EBI-676448|uniprotkb:O61349|uniprotkb:Q8IQ45|uniprotkb:Q8IQ46|uniprotkb:Q8T0C7|uniprotkb:Q9VRH7|uniprotkb:Q9VRH8|uniprotkb:Q9VRH9|uniprotkb:Q9VRI2|ensemblmetazoa:FBpp0076903 intact:EBI-139773|ensemblmetazoa:FBpp0083745 psi-mi:prod_drome(display_long)|uniprotkb:slgA(gene name)|psi-mi:slgA(display_short)|uniprotkb:slg(gene name synonym)|uniprotkb:Proline oxidase(gene name synonym)|uniprotkb:Protein sluggish-A(gene name synonym)|uniprotkb:CG1417(orf name) psi-mi:q9vcq9_drome(display_long)|uniprotkb:Dmel\CG6733(gene name)|psi-mi:Dmel\CG6733(display_short)|uniprotkb:CG6733(orf name)|uniprotkb:Dmel_CG6733(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110824|imex:IM-9552-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523433.2|refseq:NP_728422.1|refseq:NP_728423.1|refseq:NP_728424.1|refseq:NP_728425.1|refseq:NP_996526.1|refseq:NP_996527.1|refseq:NP_996528.1|flybase:FBgn0003423|refseq:NP_001245791.1|refseq:NP_001245792.1|refseq:NP_001245793.1|refseq:NP_001245794.1|refseq:NP_001245795.1|refseq:NP_001245796.1|ensemblmetazoa:FBgn0003423(gene)|ensemblmetazoa:FBtr0077204(transcript)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004657"(proline dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006562"(proline catabolic process)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010133"(proline catabolic process to glutamate)|go:"GO:0042331"(phototaxis)|go:"GO:0071949"(FAD binding)|interpro:IPR002872(Proline dehydrogenase)|interpro:IPR015659(Proline oxidase)|interpro:IPR029041|reactome:R-DME-389661|reactome:R-DME-70688 refseq:NP_651123.1|flybase:FBgn0039052|ensemblmetazoa:FBgn0039052(gene)|ensemblmetazoa:FBtr0084352(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006520"(cellular amino acid metabolic process)|interpro:IPR002933(Peptidase M20)|interpro:IPR010159(N-acyl-L-amino-acid amidohydrolase)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR036264 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:d1zC2JVk8RJQxiDJGDMCk5M7iSw7227 rogid:zZImGPgH6AumfnICShEN7yQxi8w7227 intact-crc:A5983AB1BD3224D7|rigid:rywrLbC9j54Lx+wbEzkxtW3AXog false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9U1L7 uniprotkb:Q8MQK5 intact:EBI-2110836|ensemblmetazoa:FBpp0311615 intact:EBI-2110829|ensemblmetazoa:FBpp0075353 psi-mi:q9u1l7_drome(display_long)|uniprotkb:CG11380(orf name)|uniprotkb:"EG:BACR42I17.7"(gene name)|psi-mi:"EG:BACR42I17.7"(display_short) psi-mi:q8mqk5_drome(display_long)|uniprotkb:CG7945(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110833|imex:IM-9552-258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040359|ensemblmetazoa:FBgn0040359(gene)|ensemblmetazoa:FBtr0345506(transcript) flybase:FBgn0036505|ensemblmetazoa:FBgn0036505(gene)|ensemblmetazoa:FBtr0075600(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR037689 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:XKDOWi9S+WhPTqkmnMaRwJjRWfU7227 rogid:2n2dmH+5GUVb/3T9ZLBmHXq2pyg7227 intact-crc:CA527D64E777CC00|rigid:iH4Pr6VQ9qKzihjCtWv/qGiuiXI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q01083 uniprotkb:Q0IGT7 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-2110845 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:q0igt7_drome(display_long)|uniprotkb:btn-RA(gene name)|psi-mi:btn-RA(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110842|imex:IM-9552-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|interpro:IPR042634|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:Rm8jhbEWp40Xrittix6C6Jqy/BA7227 intact-crc:ECE3B61CCE12F72F|rigid:zRI1K4Cj9oQwNMzNcJU0EIY/V+8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VQH5 uniprotkb:P11046 intact:EBI-2110851|uniprotkb:Q8SYU9|ensemblmetazoa:FBpp0077304 intact:EBI-176205|uniprotkb:A4V0D8|uniprotkb:Q6AWM6|uniprotkb:Q8SWY0|uniprotkb:Q26328|uniprotkb:Q9VLW6|uniprotkb:Q9XZT4|ensemblmetazoa:FBpp0079113|ensemblmetazoa:FBpp0079114 psi-mi:q9vqh5_drome(display_long)|uniprotkb:CG2973(orf name)|uniprotkb:Cpr23B(gene name)|psi-mi:Cpr23B(display_short)|uniprotkb:DmelCpr23B(gene name synonym)|uniprotkb:Dmel\CG2973(gene name synonym)|uniprotkb:Dmel_CG2973(orf name) psi-mi:lamb1_drome(display_long)|uniprotkb:LanB1(gene name)|psi-mi:LanB1(display_short)|uniprotkb:lamB1(gene name synonym)|uniprotkb:CG7123(orf name)|uniprotkb:Laminin B1 chain(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110856|imex:IM-9552-260 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608718.1|flybase:FBgn0031467|ensemblmetazoa:FBgn0031467(gene)|ensemblmetazoa:FBtr0077618(transcript)|go:"GO:0008010"(structural constituent of chitin-based larval cuticle)|go:"GO:0031012"(extracellular matrix)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0062129"(chitin-based extracellular matrix)|interpro:IPR000618(Insect cuticle protein)|interpro:IPR031311 refseq:NP_476618.1|refseq:NP_723319.1|flybase:FBgn0261800|ensemblmetazoa:FBgn0261800(gene)|ensemblmetazoa:FBtr0079490(transcript)|ensemblmetazoa:FBtr0079491(transcript)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008406"(gonad development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043256"(laminin complex)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048513"(animal organ development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0071711"(basement membrane organization)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|reactome:R-DME-1474228|reactome:R-DME-3000157|reactome:R-DME-373752|reactome:R-DME-381426|reactome:R-DME-446107|reactome:R-DME-8957275 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:yOG1YOrH5BcvfmINyhGnGzOtO8c7227 rogid:TRSRMFsah1k5KuLNdTjDqK0pttY7227 intact-crc:404B0407B6F4BAC6|rigid:2fOe5QzeRxMhQLgiRcNMT56CJkw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24175 uniprotkb:Q0KIB0 intact:EBI-128624|ensemblmetazoa:FBpp0073824 intact:EBI-2110861|ensemblmetazoa:FBpp0110103 psi-mi:q24175_drome(display_long)|uniprotkb:dah(gene name)|psi-mi:dah(display_short)|uniprotkb:Apd(gene name synonym)|uniprotkb:Dah(gene name synonym)|uniprotkb:Dmel\CG6157(gene name synonym)|uniprotkb:"fs(1)dah"(gene name synonym)|uniprotkb:Dmel_CG6157(orf name)|uniprotkb:CG6157(orf name) psi-mi:q0kib0_drome(display_long)|uniprotkb:CG34113(orf name)|uniprotkb:side-III(gene name)|psi-mi:side-III(display_short)|uniprotkb:34113(gene name synonym)|uniprotkb:CG10989(gene name synonym)|uniprotkb:CG14677(gene name synonym)|uniprotkb:CG14678(gene name synonym)|uniprotkb:CT34460(gene name synonym)|uniprotkb:"Dm_3R:9314"(gene name synonym)|uniprotkb:Dmel\CG34113(gene name synonym)|uniprotkb:Dmel_CG34113(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110866|imex:IM-9552-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511162.1|flybase:FBgn0015926|ensemblmetazoa:FBgn0015926(gene)|ensemblmetazoa:FBtr0074007(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007349"(cellularization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR043145 refseq:NP_001036681.1|flybase:FBgn0083949|ensemblmetazoa:FBgn0083949(gene)|ensemblmetazoa:FBtr0110806(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:IIYG0wJu9SF227t5+d7Dux1TNn07227 rogid:0BciLQziirfjrxPZHu3hxMZ5/Kg7227 intact-crc:8E3DCAD402E97C52|rigid:s62req6qWvEkcyoAnEWGQnc6qOY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18413 uniprotkb:Q9VJJ0 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110891|imex:IM-9552-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:4F01C215B9A84AC0|rigid:jE20e6x9QGE4CAcR3INtz+8/Uy8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VA32 uniprotkb:Q9VEN3 intact:EBI-84133|ensemblmetazoa:FBpp0085072 intact:EBI-168516|ensemblmetazoa:FBpp0082840 psi-mi:q9va32_drome(display_long)|uniprotkb:Cpr100A(gene name)|psi-mi:Cpr100A(display_short)|uniprotkb:CG12045(orf name)|uniprotkb:DmelCpr100A(gene name synonym)|uniprotkb:Dmel\CG12045(gene name synonym)|uniprotkb:Dmel_CG12045(orf name) psi-mi:q9ven3_drome(display_long)|uniprotkb:GckIII(gene name)|psi-mi:GckIII(display_short)|uniprotkb:GckIII-RA(gene name synonym)|uniprotkb:Dmel\CG5169(gene name synonym)|uniprotkb:GCKIII(gene name synonym)|uniprotkb:Gck III(gene name synonym)|uniprotkb:STLK3(gene name synonym)|uniprotkb:dGCKIII(gene name synonym)|uniprotkb:wheezy(gene name synonym)|uniprotkb:Dmel_CG5169(orf name)|uniprotkb:CG5169(orf name)|uniprotkb:dGckIII(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110871|imex:IM-9552-262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651829.1|flybase:FBgn0039805|ensemblmetazoa:FBgn0039805(gene)|ensemblmetazoa:FBtr0085710(transcript)|go:"GO:0008010"(structural constituent of chitin-based larval cuticle)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0062129"(chitin-based extracellular matrix)|interpro:IPR000618(Insect cuticle protein) refseq:NP_650596.1|flybase:FBgn0266465|ensemblmetazoa:FBgn0266465(gene)|ensemblmetazoa:FBtr0083399(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0019991"(septate junction assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060439"(trachea morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-111465|reactome:R-DME-75153 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of random pairs 9_2006"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:xy4S11eB7HbFOpTK5nqImZRZTtA7227 rogid:jcP32w0LAsYJaIgrJEAhmghvNVk7227 intact-crc:BC4640292FF211A0|rigid:0TV9aouFYS0Ymtk82zRktUfQFgk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:Q9VTQ9 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-145364|ensemblmetazoa:FBpp0075772|ensemblmetazoa:FBpp0312163 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:q9vtq9_drome(display_long)|uniprotkb:DmCG7257(gene name synonym)|uniprotkb:Dm_Rpt4c(gene name synonym)|uniprotkb:Dmel\CG7257(gene name synonym)|uniprotkb:Dmel_CG7257(orf name)|uniprotkb:7257(gene name synonym)|uniprotkb:Rpt4R(gene name)|psi-mi:Rpt4R(display_short)|uniprotkb:CG7257(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110876|imex:IM-9552-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_648525.1|flybase:FBgn0036224|refseq:NP_001287039.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|ensemblmetazoa:FBtr0346545(transcript)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|ensemblmetazoa:FBgn0036224(gene)|ensemblmetazoa:FBtr0076040(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:qKddY9ayACDKkIZPibAZTgXAvJE7227 intact-crc:CBB5F12BABA262F3|rigid:+qLnwiDSCEezDn8SM3MpgKYKbDI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:Q9VTQ9 intact:EBI-2110884 intact:EBI-145364|ensemblmetazoa:FBpp0075772|ensemblmetazoa:FBpp0312163 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:q9vtq9_drome(display_long)|uniprotkb:DmCG7257(gene name synonym)|uniprotkb:Dm_Rpt4c(gene name synonym)|uniprotkb:Dmel\CG7257(gene name synonym)|uniprotkb:Dmel_CG7257(orf name)|uniprotkb:7257(gene name synonym)|uniprotkb:Rpt4R(gene name)|psi-mi:Rpt4R(display_short)|uniprotkb:CG7257(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110881|imex:IM-9552-264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_648525.1|flybase:FBgn0036224|refseq:NP_001287039.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|ensemblmetazoa:FBtr0346545(transcript)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|ensemblmetazoa:FBgn0036224(gene)|ensemblmetazoa:FBtr0076040(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:qKddY9ayACDKkIZPibAZTgXAvJE7227 intact-crc:06ACB39757106864|rigid:wF8L5iCX8+tWEL5ubmf875cPj1E false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:P55035 intact:EBI-2110884 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110906|imex:IM-9552-268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 intact-crc:5D05C997E1746F3A|rigid:uxD+P/qBnYVBG32mkOoyqXhOLyU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:P48601 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110896|imex:IM-9552-266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:6A521C189DB69373|rigid:Ss6aXu7qyWR8q2EVd2KaK8Pe4S8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9V5C6 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110901|imex:IM-9552-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 intact-crc:51291ED5CD882907|rigid:zwOn8HQXDinE4NRTAzUTzrnpezo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V5C6 uniprotkb:Q9VK14 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 intact:EBI-166677|ensemblmetazoa:FBpp0080028 psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110926|imex:IM-9552-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 intact-crc:9B511CB5593D0B0E|rigid:qVxX63mLEx2xZtEkGkRjsRATv/M false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K306 uniprotkb:P48609 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 intact:EBI-94216|intact:EBI-1627775|uniprotkb:Q94878|uniprotkb:Q9V7D8|ensemblmetazoa:FBpp0086483 psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:cdk5_drome(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:CG8203(orf name)|uniprotkb:Cell division protein kinase 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110911|imex:IM-9552-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 refseq:NP_477080.1|flybase:FBgn0013762|go:"GO:0106310"(protein serine kinase activity)|ensemblmetazoa:FBgn0013762(gene)|ensemblmetazoa:FBtr0087350(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007629"(flight behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051642"(centrosome localization)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-399956|reactome:R-DME-6804756|go:"GO:0106311"|dip:DIP-22131N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 rogid:VNwgPo7AEv+BIJY9ncTvrZA2jQI7227 intact-crc:30806D88ECA0B0E5|rigid:p3+3Vzzxo/MfKGpvwurNSTowbUI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:O18413 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110921|imex:IM-9552-270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:D07A3F7E8CDAFFF3|rigid:03YI6RDD91uYOxYoKYTgKmCwLkU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VCD5 uniprotkb:Q8IRD1 intact:EBI-139147|ensemblmetazoa:FBpp0083927 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110944|imex:IM-9552-274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 intact-crc:59154E038F041A19|rigid:i3jbrLIHYb4Hdq+osZTreY4aNbM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:Q9VK14 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-166677|ensemblmetazoa:FBpp0080028 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110931|imex:IM-9552-272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 intact-crc:D74B2040C408A690|rigid:Vg/LwjUJgQrnGLMcp05BVX2PmtU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VCD5 uniprotkb:P48601 intact:EBI-139147|ensemblmetazoa:FBpp0083927 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110936|imex:IM-9552-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:90C07F515552A37A|rigid:vxFKzVYTady7f5P06qeR4BMR3dc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9VJJ0 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110959|imex:IM-9552-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:AFE9C271A437B2DF|rigid:ckbv5IEu7l4tkPCSq7Zs+T4WI68 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:O18413 intact:EBI-2110884 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110949|imex:IM-9552-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:9D4A222C026C2A68|rigid:pjsv7dQ32457QyZLuCecaKgc3yU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:P18053 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110954|imex:IM-9552-276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 intact-crc:27A6463311002741|rigid:kZX3kgkQdDTlisxp1ESYHPhURAU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q8T8V8 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-1630532 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110964|imex:IM-9552-278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 intact-crc:93BBEDC50AB1DBDB|rigid:cR2+8yTiEPIj6qEJvPuHRZd0iSo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q5BI50 uniprotkb:O77430 intact:EBI-191142|intact:EBI-2110969|ensemblmetazoa:FBpp0087897|ensemblmetazoa:FBpp0290569 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:q5bi50_drome(display_long)|uniprotkb:Cul4(gene name)|psi-mi:Cul4(display_short)|uniprotkb:Cul-4(gene name synonym)|uniprotkb:cul-4(gene name synonym)|uniprotkb:cul-4-RA(gene name synonym)|uniprotkb:CUL4(gene name synonym)|uniprotkb:Cullin4(gene name synonym)|uniprotkb:DMcul-4(gene name synonym)|uniprotkb:Dmel\CG8711(gene name synonym)|uniprotkb:cul4(gene name synonym)|uniprotkb:dCul4(gene name synonym)|uniprotkb:CG8711(orf name)|uniprotkb:Dmel_CG8711(orf name) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110973|imex:IM-9552-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163084.1|refseq:NP_610352.2|flybase:FBgn0033260|ensemblmetazoa:FBgn0033260(gene)|ensemblmetazoa:FBtr0088821(transcript)|ensemblmetazoa:FBtr0301355(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-110314|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-8951664 refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:T0GqwnVU4K6nKhenExECvtzS+UE7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 intact-crc:0513347B268DA05B|rigid:yX0Ks4ULtq8cWmmr0N2NB1HCIJQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95TK2 uniprotkb:O77430 intact:EBI-2110978|ensemblmetazoa:FBpp0072065 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:q95tk2_drome(display_long)|uniprotkb:CG3060(orf name)|uniprotkb:mr(gene name)|psi-mi:mr(display_short) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110982|imex:IM-9552-280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0002791|ensemblmetazoa:FBgn0002791(gene)|ensemblmetazoa:FBtr0072156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR014786(Anaphase promoting complex subunit 2)|interpro:IPR016158(Cullin homology)|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR044554 refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:cm2LazALSk/YqJsnjjeZFtZXA6k7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 intact-crc:235A3E0645E7DA6D|rigid:6wrXcEAdyEjGpjCjyOlrYl4GgPs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:P18053 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110987|imex:IM-9552-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 intact-crc:F9F683DADCC7884B|rigid:XvopFFNF4GMNqqsx7tazvkm0l2A false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:P08182 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-128120|uniprotkb:Q76NS4|uniprotkb:Q9VYU4|ensemblmetazoa:FBpp0089135 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:csk2b_drome(display_long)|uniprotkb:CkIIbeta(gene name)|psi-mi:CkIIbeta(display_short)|uniprotkb:Cask-II-b(gene name synonym)|uniprotkb:CG15224(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111002|imex:IM-9552-284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N flybase:FBgn0000259|refseq:NP_001014731.1|refseq:NP_511131.3|refseq:NP_542940.1|refseq:NP_727561.1|refseq:NP_727562.1|refseq:NP_996415.1|refseq:NP_001245628.1|ensemblmetazoa:FBgn0000259(gene)|ensemblmetazoa:FBtr0073562(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016319"(mushroom body development)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0099523"(presynaptic cytosol)|reactome:R-DME-8934903|interpro:IPR000704(Casein kinase II, regulatory subunit)|reactome:R-DME-8948751|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6798695|reactome:R-DME-6804756|reactome:R-DME-6814122|dip:DIP-17048N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:xiER9RXJ5YAbvII+LPCvwzp3s/47227 intact-crc:A2A311A7863C8CB3|rigid:C56o6tJQmA5Xk9jNy9xbGO71Mz4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P11147 uniprotkb:Q24133 intact:EBI-75181|uniprotkb:Q3KN45|uniprotkb:Q8SXQ4|uniprotkb:Q9VFB0|ensemblmetazoa:FBpp0082514|ensemblmetazoa:FBpp0082515|ensemblmetazoa:FBpp0082516|ensemblmetazoa:FBpp0082517|ensemblmetazoa:FBpp0082518|ensemblmetazoa:FBpp0082519|ensemblmetazoa:FBpp0307982 intact:EBI-87640|uniprotkb:Q9VRP0|ensemblmetazoa:FBpp0076829|ensemblmetazoa:FBpp0076830 psi-mi:hsp7d_drome(display_long)|uniprotkb:Hsc70-4(gene name)|psi-mi:Hsc70-4(display_short)|uniprotkb:Hsc4(gene name synonym)|uniprotkb:CG4264(orf name)|uniprotkb:Heat shock 70 kDa protein 88E(gene name synonym) psi-mi:dnaj1_drome(display_long)|uniprotkb:DnaJ-1(gene name)|psi-mi:DnaJ-1(display_short)|uniprotkb:DROJ1(gene name synonym)|uniprotkb:CG10578(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110992|imex:IM-9552-282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524356.1|refseq:NP_731987.1|refseq:NP_731988.1|refseq:NP_731989.1|refseq:NP_788679.1|refseq:NP_788680.1|flybase:FBgn0266599|refseq:NP_001262586.1|dip:DIP-19158N|ensemblmetazoa:FBgn0266599(gene)|ensemblmetazoa:FBtr0083055(transcript)|ensemblmetazoa:FBtr0083056(transcript)|ensemblmetazoa:FBtr0083057(transcript)|ensemblmetazoa:FBtr0083058(transcript)|ensemblmetazoa:FBtr0083059(transcript)|ensemblmetazoa:FBtr0083060(transcript)|ensemblmetazoa:FBtr0337053(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016246"(RNA interference)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097753"(membrane bending)|go:"GO:0098793"(presynapse)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11147|reactome:R-DME-3371453|reactome:R-DME-3371497|reactome:R-DME-3371571|reactome:R-DME-450408|reactome:R-DME-6798695|reactome:R-DME-72163|reactome:R-DME-8856828|reactome:R-DME-888590 refseq:NP_523936.2|refseq:NP_729086.1|ensemblmetazoa:FBgn0263106(gene)|ensemblmetazoa:FBtr0077123(transcript)|ensemblmetazoa:FBtr0077124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009408"(response to heat)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|flybase:FBgn0263106|dip:DIP-18469N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0e7AjwNXSuekfdcT63i3/qeJ5ww7227 rogid:a9IH3J+QRKijRMBTudpvE5YV/Ek7227 intact-crc:3CF5F5856FC80483|rigid:+OGdb0cbRsNMNp+2oliNMXSk2tU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:O18413 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2110997|imex:IM-9552-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:83120F661C746F9E|rigid:Kb9CFuqwQxE0lWIeJntlZrnVUCk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24474 uniprotkb:Q8MSM3 intact:EBI-2111020|uniprotkb:Q7KU26|ensemblmetazoa:FBpp0077323|ensemblmetazoa:FBpp0077325|ensemblmetazoa:FBpp0099898|ensemblmetazoa:FBpp0288676 intact:EBI-2111025 psi-mi:q24474_drome(display_long)|uniprotkb:CG3151(orf name)|uniprotkb:RBP9(gene name synonym)|uniprotkb:Rbp9(gene name)|psi-mi:Rbp9(display_short)|uniprotkb:CG15402(gene name synonym)|uniprotkb:Dmel\CG3151(gene name synonym)|uniprotkb:RBP9-2(gene name synonym)|uniprotkb:RRM10(gene name synonym)|uniprotkb:RRM9(gene name synonym)|uniprotkb:Rbp10(gene name synonym)|uniprotkb:Rpb9(gene name synonym)|uniprotkb:fes(gene name synonym)|uniprotkb:"fs(2)B"(gene name synonym)|uniprotkb:rbp(gene name synonym)|uniprotkb:rbp9(gene name synonym)|uniprotkb:rbp9a(gene name synonym)|uniprotkb:rrm10(gene name synonym)|uniprotkb:rrm9(gene name synonym)|uniprotkb:Dmel_CG3151(orf name) psi-mi:q8msm3_drome(display_long)|uniprotkb:CG8219(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111017|imex:IM-9552-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014462.1|refseq:NP_476936.3|refseq:NP_599125.1|refseq:NP_599126.1|flybase:FBgn0010263|ensemblmetazoa:FBgn0010263(gene)|ensemblmetazoa:FBtr0077638(transcript)|ensemblmetazoa:FBtr0077640(transcript)|ensemblmetazoa:FBtr0100468(transcript)|ensemblmetazoa:FBtr0290237(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0048477"(oogenesis)|go:"GO:0060856"(establishment of blood-brain barrier)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979 flybase:FBgn0035693|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:W49ehf3/lWaZcoguI/G/lXxlXZw7227 rogid:chaW+EBN77dTZq+gUMAuDnJtXiI7227 intact-crc:54219C7323845418|rigid:qXf5iNRha+LdRHJK5Bb32Z4ZYB8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:Q8T8V8 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-1630532 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111007|imex:IM-9552-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 intact-crc:68299CEB0CF5850F|rigid:eUsduHFLHCwUNlsazBRNFZ2XYrE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18413 uniprotkb:Q9VTQ9 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 intact:EBI-145364|ensemblmetazoa:FBpp0075772|ensemblmetazoa:FBpp0312163 psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:q9vtq9_drome(display_long)|uniprotkb:DmCG7257(gene name synonym)|uniprotkb:Dm_Rpt4c(gene name synonym)|uniprotkb:Dmel\CG7257(gene name synonym)|uniprotkb:Dmel_CG7257(orf name)|uniprotkb:7257(gene name synonym)|uniprotkb:Rpt4R(gene name)|psi-mi:Rpt4R(display_short)|uniprotkb:CG7257(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111012|imex:IM-9552-286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_648525.1|flybase:FBgn0036224|refseq:NP_001287039.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|ensemblmetazoa:FBtr0346545(transcript)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|ensemblmetazoa:FBgn0036224(gene)|ensemblmetazoa:FBtr0076040(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 rogid:qKddY9ayACDKkIZPibAZTgXAvJE7227 intact-crc:41BC1BE4BE1904F7|rigid:kXiTwZACAO6DLDDZMxBUzrgLwpI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN44 uniprotkb:P07909 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 intact:EBI-209336|uniprotkb:Q24359|uniprotkb:Q24360|uniprotkb:Q99361|uniprotkb:Q9VAU7|uniprotkb:Q9VAU8|ensemblmetazoa:FBpp0084669|ensemblmetazoa:FBpp0084670 psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:roa1_drome(display_long)|uniprotkb:CG9983(orf name)|uniprotkb:Hrb98DE(gene name)|psi-mi:Hrb98DE(display_short)|uniprotkb:Pen9(gene name synonym)|uniprotkb:hnRNP core protein A1-A(gene name synonym)|uniprotkb:PEN repeat clone P9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111030|imex:IM-9552-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 refseq:NP_524543.1|refseq:NP_733249.1|refseq:NP_733250.1|refseq:NP_733251.1|refseq:NP_733252.1|refseq:NP_733253.1|flybase:FBgn0001215|dip:DIP-19217N|ensemblmetazoa:FBgn0001215(gene)|ensemblmetazoa:FBtr0085300(transcript)|ensemblmetazoa:FBtr0085301(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0034046"("poly(G) binding")|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 rogid:bo8EaSjJVYic8BtyS/N6FLg5qRM7227 intact-crc:DE8ACD3CB0ADD859|rigid:Lcm4660g+4BYmKuPcjQaC+aUHMU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24474 uniprotkb:Q9VN44 intact:EBI-2111020|uniprotkb:Q7KU26|ensemblmetazoa:FBpp0077323|ensemblmetazoa:FBpp0077325|ensemblmetazoa:FBpp0099898|ensemblmetazoa:FBpp0288676 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 psi-mi:q24474_drome(display_long)|uniprotkb:CG3151(orf name)|uniprotkb:RBP9(gene name synonym)|uniprotkb:Rbp9(gene name)|psi-mi:Rbp9(display_short)|uniprotkb:CG15402(gene name synonym)|uniprotkb:Dmel\CG3151(gene name synonym)|uniprotkb:RBP9-2(gene name synonym)|uniprotkb:RRM10(gene name synonym)|uniprotkb:RRM9(gene name synonym)|uniprotkb:Rbp10(gene name synonym)|uniprotkb:Rpb9(gene name synonym)|uniprotkb:fes(gene name synonym)|uniprotkb:"fs(2)B"(gene name synonym)|uniprotkb:rbp(gene name synonym)|uniprotkb:rbp9(gene name synonym)|uniprotkb:rbp9a(gene name synonym)|uniprotkb:rrm10(gene name synonym)|uniprotkb:rrm9(gene name synonym)|uniprotkb:Dmel_CG3151(orf name) psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111054|imex:IM-9552-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014462.1|refseq:NP_476936.3|refseq:NP_599125.1|refseq:NP_599126.1|flybase:FBgn0010263|ensemblmetazoa:FBgn0010263(gene)|ensemblmetazoa:FBtr0077638(transcript)|ensemblmetazoa:FBtr0077640(transcript)|ensemblmetazoa:FBtr0100468(transcript)|ensemblmetazoa:FBtr0290237(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0048477"(oogenesis)|go:"GO:0060856"(establishment of blood-brain barrier)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979 refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:W49ehf3/lWaZcoguI/G/lXxlXZw7227 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 intact-crc:C69D79EE0CF56D07|rigid:zYOum/YWQlJzr48E+BFf1h/8HFg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24024 uniprotkb:Q9VN44 intact:EBI-2111035 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 psi-mi:q24024_drome(display_long)|uniprotkb:CG9654(orf name)|uniprotkb:Rbp4(gene name)|psi-mi:Rbp4(display_short) psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111039|imex:IM-9552-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010258|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:ZXuEdIy7FfwrDFX7rQlXRndk2KY7227 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 intact-crc:9C87C9841A102C60|rigid:0jAtgGfULG6yXEwyOCLn6uAo1Bk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN44 uniprotkb:P21187 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 intact:EBI-103658|uniprotkb:A4UZM5|uniprotkb:Q0E932|uniprotkb:Q9V8C3|ensemblmetazoa:FBpp0085915|ensemblmetazoa:FBpp0085917|ensemblmetazoa:FBpp0085919 psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:pabp_drome(display_long)|uniprotkb:pAbp(gene name)|psi-mi:pAbp(display_short)|uniprotkb:CG5119(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111044|imex:IM-9552-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 refseq:NP_476667.1|refseq:NP_725749.1|refseq:NP_725750.1|flybase:FBgn0265297|ensemblmetazoa:FBgn0265297(gene)|ensemblmetazoa:FBtr0086736(transcript)|ensemblmetazoa:FBtr0086738(transcript)|ensemblmetazoa:FBtr0086740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045202"(synapse)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048477"(oogenesis)|go:"GO:0048599"(oocyte development)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|reactome:R-DME-156827|reactome:R-DME-429947|reactome:R-DME-450408|reactome:R-DME-72649|reactome:R-DME-975956|reactome:R-DME-975957|dip:DIP-52140N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 rogid:byhDypdu0AX3W6X99vpUPFHj1Ao7227 intact-crc:DD11D64DDAD9D5FD|rigid:9enEficb1yJfxoWG2C8d8oUwMSw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN44 uniprotkb:Q9VYI0 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 intact:EBI-126770|uniprotkb:Q9NGV0|ensemblmetazoa:FBpp0073543|ensemblmetazoa:FBpp0112400|ensemblmetazoa:FBpp0297664|ensemblmetazoa:FBpp0300900|ensemblmetazoa:FBpp0305511|ensemblmetazoa:FBpp0305512 psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:q9vyi0_drome(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)|uniprotkb:fne-RB(gene name synonym)|uniprotkb:"BEST:HL02010"(gene name synonym)|uniprotkb:"BcDNA:HL02010"(gene name synonym)|uniprotkb:"BcDNA:RE25290"(gene name synonym)|uniprotkb:CR32646(gene name synonym)|uniprotkb:Dmel\CG4396(gene name synonym)|uniprotkb:FNE(gene name synonym)|uniprotkb:Fne(gene name synonym)|uniprotkb:MRE28(gene name synonym)|uniprotkb:lincRNA.985(gene name synonym)|uniprotkb:Dmel_CG4396(orf name)|uniprotkb:CG4396(orf name)|uniprotkb:cg4396(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111049|imex:IM-9552-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 ensemblmetazoa:FBgn0086675(gene)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979|reactome:R-DME-450520|reactome:R-DME-72163|ensemblmetazoa:FBtr0073712(transcript)|ensemblmetazoa:FBtr0113493(transcript)|ensemblmetazoa:FBtr0306738(transcript)|ensemblmetazoa:FBtr0308694(transcript)|ensemblmetazoa:FBtr0333319(transcript)|ensemblmetazoa:FBtr0333320(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008049"(male courtship behavior)|refseq:NP_001096965.1|refseq:NP_572842.1|flybase:FBgn0086675|refseq:NP_001245646.1|refseq:NP_001245648.1|refseq:NP_001259497.1|refseq:NP_001259498.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 rogid:IxfHiln53BTh0NS5caA9LjvUpWc7227 intact-crc:3F359FFE1755D4F7|rigid:Mv0+txnGVU08cavma7DE6yKkuC4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O76876 uniprotkb:Q9VN44 intact:EBI-119481|ensemblmetazoa:FBpp0308820 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 psi-mi:o76876_drome(display_long)|uniprotkb:ssx(gene name)|psi-mi:ssx(display_short)|uniprotkb:"EG:132E8.1"(gene name synonym)|uniprotkb:Dmel\CG3056(gene name synonym)|uniprotkb:"anon-EST:Posey102"(gene name synonym)|uniprotkb:cg3056(gene name synonym)|uniprotkb:CG3056(orf name)|uniprotkb:Dmel_CG3056(orf name) psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111059|imex:IM-9552-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0024987(gene)|ensemblmetazoa:FBtr0339773(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_569908.1|flybase:FBgn0024987 refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:52iwby+dJAYePixF0Is80HR1eYc7227 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 intact-crc:B3CEABC467B4E136|rigid:zp+WR/ygaZiuYgR7T65neFcTAXU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:P48601 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111079|imex:IM-9552-296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:9EEF1DDE176ACEE3|rigid:TBOE9yR+VY9WthuQF3FxtdE9I8Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN44 uniprotkb:Q08473 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 intact:EBI-130500|uniprotkb:Q3ZAN7|uniprotkb:Q26273|uniprotkb:Q8IH71|uniprotkb:Q8INH1|uniprotkb:Q8MSY1|uniprotkb:Q9VFT5|uniprotkb:Q9VFT6|ensemblmetazoa:FBpp0082320 psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:sqd_drome(display_long)|uniprotkb:sqd(gene name)|psi-mi:sqd(display_short)|uniprotkb:hrp40(gene name synonym)|uniprotkb:CG16901(orf name)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 40(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111064|imex:IM-9552-294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 refseq:NP_652209.1|refseq:NP_731825.1|refseq:NP_731826.1|refseq:NP_996203.1|refseq:NP_001247088.1|ensemblmetazoa:FBgn0263396(gene)|ensemblmetazoa:FBtr0082855(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035062"(omega speckle)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-450408|reactome:R-DME-72163|go:"GO:0005737"(cytoplasm)|flybase:FBgn0263396 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 rogid:NfWBBjp/8+FNG6V/9i3khE0NbJs7227 intact-crc:924741666F306ADB|rigid:aEm9RyhXo7u53FHXjs5ofbcx61Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97468 uniprotkb:Q8MSM3 intact:EBI-2111069 intact:EBI-2111025 psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:q8msm3_drome(display_long)|uniprotkb:CG8219(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111074|imex:IM-9552-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 flybase:FBgn0035693|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 rogid:chaW+EBN77dTZq+gUMAuDnJtXiI7227 intact-crc:C23257BEBB90BFAC|rigid:j6PJKrBegrJDSsmstw1KGJcfCMQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V5C6 uniprotkb:Q9VJJ0 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111099|imex:IM-9552-300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:8912142F3126815A|rigid:soxhaA9LGp0PiR4W2XKNRwhbamU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VCD5 uniprotkb:Q9VXF9 intact:EBI-139147|ensemblmetazoa:FBpp0083927 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111084|imex:IM-9552-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 intact-crc:80A6463C5C0EB464|rigid:/XcQctYZnNLudxMhWnSvVx3XeZM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:P08181 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111089|imex:IM-9552-298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:908E46B9C2ACEE11|rigid:YBkkx1mxkdfGQGqQTrbo1LH9fQk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KMP8 uniprotkb:P26270 intact:EBI-151692|intact:EBI-2109416|ensemblmetazoa:FBpp0083860|ensemblmetazoa:FBpp0083861 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 psi-mi:q7kmp8_drome(display_long)|uniprotkb:Rpn9(gene name)|psi-mi:Rpn9(display_short)|uniprotkb:06(gene name synonym)|uniprotkb:0718(gene name synonym)|uniprotkb:718(gene name synonym)|uniprotkb:CT28749(gene name synonym)|uniprotkb:Dmel\CG10230(gene name synonym)|uniprotkb:PSMD13(gene name synonym)|uniprotkb:Rpn4(gene name synonym)|uniprotkb:Rpn94(gene name synonym)|uniprotkb:S11(gene name synonym)|uniprotkb:"l(3)S071806"(gene name synonym)|uniprotkb:"l(3)S071806b"(gene name synonym)|uniprotkb:p39A(gene name synonym)|uniprotkb:rpn9(gene name synonym)|uniprotkb:Dmel_CG10230(orf name)|uniprotkb:CG10230(orf name)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym) psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111094|imex:IM-9552-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651177.1|refseq:NP_732899.1|flybase:FBgn0028691|ensemblmetazoa:FBgn0028691(gene)|ensemblmetazoa:FBtr0084469(transcript)|ensemblmetazoa:FBtr0084470(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hEc3E83aGFg8Gw9MZx51ViGA3Qk7227 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 intact-crc:7FB2F8506D3073E9|rigid:oIjWlrnLpTkdcqW+OlmW2+F73z0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:Q8T8V8 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-1630532 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111104|imex:IM-9552-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 intact-crc:640B0A525BF0109C|rigid:AXdnSq3rab4bVoDMq4RVsg6p+9E false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T8V8 uniprotkb:O18413 intact:EBI-1630532 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111109|imex:IM-9552-302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:2A9E28F2C040218C|rigid:Q/GTNoLJYQ53WL+jo5rVBOuYTD4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P92208 uniprotkb:Q9VM49 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111114|imex:IM-9552-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 intact-crc:19666FE087FF5E00|rigid:htRD6Td66NqJJpY5K0EnXW8P8s4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23572 uniprotkb:Q7K306 intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name) psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111119|imex:IM-9552-304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 intact-crc:BB77594E857F2B58|rigid:DArs+czpUbjJay1HqbJk5w3PZQE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VM49 uniprotkb:Q8T4A6 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 intact:EBI-2111146 psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:q8t4a6_drome(display_long)|uniprotkb:CG12782(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111149|imex:IM-9552-308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 flybase:FBgn0034838|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037631 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 rogid:zzzD7GjR9hAU1T05SZnQDywdDoY7227 intact-crc:DCDE667521F4770B|rigid:rTT8uaPjhSF5m7f7Aj3BFWroUOQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:Q9VTQ9 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-145364|ensemblmetazoa:FBpp0075772|ensemblmetazoa:FBpp0312163 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:q9vtq9_drome(display_long)|uniprotkb:DmCG7257(gene name synonym)|uniprotkb:Dm_Rpt4c(gene name synonym)|uniprotkb:Dmel\CG7257(gene name synonym)|uniprotkb:Dmel_CG7257(orf name)|uniprotkb:7257(gene name synonym)|uniprotkb:Rpt4R(gene name)|psi-mi:Rpt4R(display_short)|uniprotkb:CG7257(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111124|imex:IM-9552-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 refseq:NP_648525.1|flybase:FBgn0036224|refseq:NP_001287039.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|ensemblmetazoa:FBtr0346545(transcript)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|ensemblmetazoa:FBgn0036224(gene)|ensemblmetazoa:FBtr0076040(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:qKddY9ayACDKkIZPibAZTgXAvJE7227 intact-crc:2CDEADC12295D7C7|rigid:Q1keNbmb9dnBmu+TLinv1vrpb50 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KTP7 uniprotkb:Q9V5C6 intact:EBI-196108|intact:EBI-2111129|intact:EBI-498562|uniprotkb:Q494G2|ensemblmetazoa:FBpp0306241|ensemblmetazoa:FBpp0306242|ensemblmetazoa:FBpp0306243|ensemblmetazoa:FBpp0306244|ensemblmetazoa:FBpp0306245 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 psi-mi:q7ktp7_drome(display_long)|uniprotkb:CG5822(gene name)|psi-mi:CG5822(display_short)|uniprotkb:Dmel\CG44001(gene name synonym)|uniprotkb:CG31919(orf name)|uniprotkb:CG44001(orf name)|uniprotkb:Dmel_CG44001(orf name) psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111132|imex:IM-9552-306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264743|refseq:NP_001033874.2|refseq:NP_001162882.2|refseq:NP_608900.3|refseq:NP_723051.2|refseq:NP_723052.2|ensemblmetazoa:FBgn0264743(gene)|ensemblmetazoa:FBtr0334124(transcript)|ensemblmetazoa:FBtr0334125(transcript)|ensemblmetazoa:FBtr0334126(transcript)|ensemblmetazoa:FBtr0334127(transcript)|ensemblmetazoa:FBtr0334128(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nmd2MIuypaUtOVbcArZIiNgUULo7227 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 intact-crc:43291C26B7BC9DD3|rigid:AdIZ6E8/3JHAuT263AIlLENwr8w false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97468 uniprotkb:Q7JN15 intact:EBI-2111069 intact:EBI-2111140|ensemblmetazoa:FBpp0084256 psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:q7jn15_drome(display_long)|uniprotkb:msi(gene name)|psi-mi:msi(display_short)|uniprotkb:CG5099(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111137|imex:IM-9552-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 flybase:FBgn0011666|ensemblmetazoa:FBgn0011666(gene)|ensemblmetazoa:FBtr0084882(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0001709"(cell fate determination)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022416"(chaeta development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 rogid:nl81bRYxT/uQS/uagdpSq92reJg7227 intact-crc:5CC3CE4EA51F1ECD|rigid:4ZplqA6gy6I01/PDlzBCnhE5b58 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9W418 uniprotkb:P25867 intact:EBI-114005|ensemblmetazoa:FBpp0070894|ensemblmetazoa:FBpp0311816 intact:EBI-196394|uniprotkb:Q9VFG6|ensemblmetazoa:FBpp0082477|ensemblmetazoa:FBpp0302691|ensemblmetazoa:FBpp0307824 psi-mi:q9w418_drome(display_long)|uniprotkb:Ubi-p5E(gene name)|psi-mi:Ubi-p5E(display_short)|uniprotkb:CG32744(orf name)|uniprotkb:CG18282(gene name synonym)|uniprotkb:CR32744(gene name synonym)|uniprotkb:DmUbi-p5E(gene name synonym)|uniprotkb:Dmel\CG32744(gene name synonym)|uniprotkb:UB(gene name synonym)|uniprotkb:Ub(gene name synonym)|uniprotkb:Ubi(gene name synonym)|uniprotkb:Ubiq(gene name synonym)|uniprotkb:Dmel_CG32744(orf name)|uniprotkb:DmUb(gene name synonym) psi-mi:ubcd1_drome(display_long)|uniprotkb:eff(gene name)|psi-mi:eff(display_short)|uniprotkb:UbcD1(gene name synonym)|uniprotkb:CG7425(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Protein effete(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111154|imex:IM-9552-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0086558(gene)|ensemblmetazoa:FBtr0070933(transcript)|ensemblmetazoa:FBtr0345892(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|reactome:R-DME-5607761|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5358346|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689877|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-912631|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-983168|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948747|interpro:IPR019956|reactome:R-DME-195253|interpro:IPR029071|reactome:R-DME-201681|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-2173788|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-174048|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-382556|reactome:R-DME-174178|reactome:R-DME-450408|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-4608870|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|refseq:NP_727078.1|flybase:FBgn0086558|refseq:NP_001284937.1 refseq:NP_001262578.1|refseq:NP_001262579.1|refseq:NP_731941.1|flybase:FBgn0011217|dip:DIP-18953N|ensemblmetazoa:FBgn0011217(gene)|ensemblmetazoa:FBtr0083018(transcript)|ensemblmetazoa:FBtr0310554(transcript)|ensemblmetazoa:FBtr0336876(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051276"(chromosome organization)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1234176|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176412|reactome:R-DME-179409|reactome:R-DME-201451|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-5689896|reactome:R-DME-69017|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8951664|reactome:R-DME-9033241|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nji68Fj8jQXcZi1dmH2WkapaGFU7227 rogid:m591n40BVy1LgRJXj1+X1FvIbzc7227 intact-crc:09C1030683BE2F92|rigid:0kWYoaAVrNR+npDkNLm/VsX4O7w false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24210-3 uniprotkb:Q7K306 intact:EBI-214451|ensemblmetazoa:FBpp0083559 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 psi-mi:q24210-3(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:cmg(gene name synonym)|uniprotkb:Caki(gene name synonym)|uniprotkb:CG6703(orf name)|uniprotkb:Calcium/calmodulin-dependent protein kinase(gene name synonym) psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111159|imex:IM-9552-310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-214423(caki_drome)|ensemblmetazoa:FBgn0013759(gene)|ensemblmetazoa:FBtr0084161(transcript) refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:kRJnLUWt4ROj4wv579+0RfYY48c7227 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 intact-crc:9A3829A0C0073358|rigid:1j4R13XjJ/eJOfL9jmT6Bgvx5Ts false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P68198 uniprotkb:P25867 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N intact:EBI-196394|uniprotkb:Q9VFG6|ensemblmetazoa:FBpp0082477|ensemblmetazoa:FBpp0302691|ensemblmetazoa:FBpp0307824 psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:ubcd1_drome(display_long)|uniprotkb:eff(gene name)|psi-mi:eff(display_short)|uniprotkb:UbcD1(gene name synonym)|uniprotkb:CG7425(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Protein effete(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111182|imex:IM-9552-314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 refseq:NP_001262578.1|refseq:NP_001262579.1|refseq:NP_731941.1|flybase:FBgn0011217|dip:DIP-18953N|ensemblmetazoa:FBgn0011217(gene)|ensemblmetazoa:FBtr0083018(transcript)|ensemblmetazoa:FBtr0310554(transcript)|ensemblmetazoa:FBtr0336876(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051276"(chromosome organization)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1234176|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176412|reactome:R-DME-179409|reactome:R-DME-201451|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-5689896|reactome:R-DME-69017|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8951664|reactome:R-DME-9033241|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 rogid:m591n40BVy1LgRJXj1+X1FvIbzc7227 intact-crc:65513C31EA4C16E5|rigid:rShUfEg5hv1W5+LCxOx86/ouOqk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJ33 uniprotkb:Q8IRD1 intact:EBI-90023|uniprotkb:Q29QE5|ensemblmetazoa:FBpp0080733|ensemblmetazoa:FBpp0309711 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 psi-mi:nedd8_drome(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:CG10679(orf name)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym) psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111164|imex:IM-9552-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609919.1|flybase:FBgn0032725|ensemblmetazoa:FBgn0032725(gene)|ensemblmetazoa:FBtr0081192(transcript)|ensemblmetazoa:FBtr0342928(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030431"(sleep)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-DME-5689603|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-917937|refseq:NP_001286070.1 refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:3P7TFMLheJ3IKTDNacGZdCxjrVc7227 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 intact-crc:71B7EE344C44D786|rigid:yRlPn+KJL0XEWe8ZRKe6OhrtOOg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:Q9VCD5 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-139147|ensemblmetazoa:FBpp0083927 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111169|imex:IM-9552-312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 intact-crc:834BBB76749F8264|rigid:2v1HPtqLorfHHSTsjCUgtj20G1c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24133 uniprotkb:Q7KT11 intact:EBI-87640|uniprotkb:Q9VRP0|ensemblmetazoa:FBpp0076829|ensemblmetazoa:FBpp0076830 intact:EBI-2111177|uniprotkb:Q7KT12|ensemblmetazoa:FBpp0080946|ensemblmetazoa:FBpp0080948|ensemblmetazoa:FBpp0292068|ensemblmetazoa:FBpp0292069|ensemblmetazoa:FBpp0308639|ensemblmetazoa:FBpp0308640 psi-mi:dnaj1_drome(display_long)|uniprotkb:DnaJ-1(gene name)|psi-mi:DnaJ-1(display_short)|uniprotkb:DROJ1(gene name synonym)|uniprotkb:CG10578(orf name) psi-mi:q7kt11_drome(display_long)|uniprotkb:CG9331(orf name)|uniprotkb:Dmel_CG9331(orf name)|uniprotkb:Dmel\CG9331(gene name)|psi-mi:Dmel\CG9331(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111174|imex:IM-9552-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523936.2|refseq:NP_729086.1|ensemblmetazoa:FBgn0263106(gene)|ensemblmetazoa:FBtr0077123(transcript)|ensemblmetazoa:FBtr0077124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009408"(response to heat)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|flybase:FBgn0263106|dip:DIP-18469N refseq:NP_001188857.1|refseq:NP_001188858.1|refseq:NP_610062.2|refseq:NP_788081.1|flybase:FBgn0032889|refseq:NP_995737.2|refseq:NP_001286108.1|ensemblmetazoa:FBgn0032889(gene)|ensemblmetazoa:FBtr0081417(transcript)|ensemblmetazoa:FBtr0081419(transcript)|ensemblmetazoa:FBtr0302942(transcript)|ensemblmetazoa:FBtr0302943(transcript)|ensemblmetazoa:FBtr0339559(transcript)|ensemblmetazoa:FBtr0339560(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0051287"(NAD binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:a9IH3J+QRKijRMBTudpvE5YV/Ek7227 rogid:J+yjToZ6bK4XclK6opJc17ufNTA7227 intact-crc:D144AF739E1AE94D|rigid:PW4/lqu06K27ZL6DJADVgVdkz5k false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IGZ0 uniprotkb:Q24210 intact:EBI-2111200 intact:EBI-214423|uniprotkb:Q24272|uniprotkb:Q86P03|uniprotkb:Q86P17|uniprotkb:Q8SX09|uniprotkb:Q9VD77|uniprotkb:Q9VD78|uniprotkb:Q9VD79|uniprotkb:B5X553|ensemblmetazoa:FBpp0083559 psi-mi:q8igz0_drome(display_long)|uniprotkb:CG14895(orf name)|uniprotkb:Pak3(gene name)|psi-mi:Pak3(display_short) psi-mi:cskp_drome(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:cmg(gene name synonym)|uniprotkb:CG6703(orf name)|uniprotkb:Caki(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111197|imex:IM-9552-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0044826|go:"GO:0001726"(ruffle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0007520"(myoblast fusion)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936 refseq:NP_001097862.1|refseq:NP_524441.2|refseq:NP_732661.1|refseq:NP_732662.2|flybase:FBgn0013759|dip:DIP-19769N|ensemblmetazoa:FBgn0013759(gene)|ensemblmetazoa:FBtr0084161(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040011"(locomotion)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-DME-212676|reactome:R-DME-6794361 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Y1jDux5rwyj+DFTXhrmiQOfn0HI7227 rogid:kRJnLUWt4ROj4wv579+0RfYY48c7227 intact-crc:241CF45085A09837|rigid:i4St5Ve2PNRNscAmgEW+E3ISDjY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O97468 uniprotkb:Q9VYI0 intact:EBI-2111069 intact:EBI-126770|uniprotkb:Q9NGV0|ensemblmetazoa:FBpp0073543|ensemblmetazoa:FBpp0112400|ensemblmetazoa:FBpp0297664|ensemblmetazoa:FBpp0300900|ensemblmetazoa:FBpp0305511|ensemblmetazoa:FBpp0305512 psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:q9vyi0_drome(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)|uniprotkb:fne-RB(gene name synonym)|uniprotkb:"BEST:HL02010"(gene name synonym)|uniprotkb:"BcDNA:HL02010"(gene name synonym)|uniprotkb:"BcDNA:RE25290"(gene name synonym)|uniprotkb:CR32646(gene name synonym)|uniprotkb:Dmel\CG4396(gene name synonym)|uniprotkb:FNE(gene name synonym)|uniprotkb:Fne(gene name synonym)|uniprotkb:MRE28(gene name synonym)|uniprotkb:lincRNA.985(gene name synonym)|uniprotkb:Dmel_CG4396(orf name)|uniprotkb:CG4396(orf name)|uniprotkb:cg4396(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111187|imex:IM-9552-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 ensemblmetazoa:FBgn0086675(gene)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979|reactome:R-DME-450520|reactome:R-DME-72163|ensemblmetazoa:FBtr0073712(transcript)|ensemblmetazoa:FBtr0113493(transcript)|ensemblmetazoa:FBtr0306738(transcript)|ensemblmetazoa:FBtr0308694(transcript)|ensemblmetazoa:FBtr0333319(transcript)|ensemblmetazoa:FBtr0333320(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008049"(male courtship behavior)|refseq:NP_001096965.1|refseq:NP_572842.1|flybase:FBgn0086675|refseq:NP_001245646.1|refseq:NP_001245648.1|refseq:NP_001259497.1|refseq:NP_001259498.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 rogid:IxfHiln53BTh0NS5caA9LjvUpWc7227 intact-crc:0D9E2ABAD6BF4B61|rigid:sD09Ktl17sn3oYFbM+nbowdnWO4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P92208 uniprotkb:P48601 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111192|imex:IM-9552-316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:092FFA6D6994B219|rigid:Qnx6d6yMc4tnDb3ZRDfuLb454N8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P17917 uniprotkb:Q9VX15 intact:EBI-148806|intact:EBI-1628820|uniprotkb:Q9V909|uniprotkb:Q540V1|ensemblmetazoa:FBpp0085619|ensemblmetazoa:FBpp0089395 intact:EBI-88723|uniprotkb:Q8T033|ensemblmetazoa:FBpp0074246 psi-mi:pcna_drome(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)|uniprotkb:Mutagen-sensitive 209 protein(gene name synonym)|uniprotkb:mus209(gene name synonym)|uniprotkb:CG9193(orf name)|uniprotkb:PCNA1(gene name synonym) psi-mi:q9vx15_drome(display_long)|uniprotkb:Rfc37(gene name)|psi-mi:Rfc37(display_short)|uniprotkb:DmRFC2(gene name synonym)|uniprotkb:Dmel\CG8142(gene name synonym)|uniprotkb:RFC2(gene name synonym)|uniprotkb:RfC(gene name synonym)|uniprotkb:CG8142(orf name)|uniprotkb:Dmel_CG8142(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111207|imex:IM-9552-318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476905.1|refseq:NP_995904.1|flybase:FBgn0005655|dip:DIP-20560N|reactome:R-DME-5358565|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6804114|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183|reactome:R-DME-110320|ensemblmetazoa:FBgn0005655(gene)|ensemblmetazoa:FBtr0086307(transcript)|ensemblmetazoa:FBtr0086308(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0009411"(response to UV)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043626"(PCNA complex)|go:"GO:0072702"(response to methyl methanesulfonate)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:4HK1|reactome:R-DME-110312|reactome:R-DME-110314 refseq:NP_573245.1|flybase:FBgn0030871|ensemblmetazoa:FBgn0030871(gene)|ensemblmetazoa:FBtr0074472(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-174411|reactome:R-DME-176187|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696397|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-69091|reactome:R-DME-110320 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:JlorjL2CuAoJHo8z4Cnb16+Muf87227 rogid:gmizLC5Gx1pjWRriqokodbrdZVo7227 intact-crc:16A461052C47EEF9|rigid:L7py5uWzWoI/2OIEMlGLOFc3rTM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXF9 uniprotkb:Q9VJ33 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 intact:EBI-90023|uniprotkb:Q29QE5|ensemblmetazoa:FBpp0080733|ensemblmetazoa:FBpp0309711 psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:nedd8_drome(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:CG10679(orf name)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111212|imex:IM-9552-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) refseq:NP_609919.1|flybase:FBgn0032725|ensemblmetazoa:FBgn0032725(gene)|ensemblmetazoa:FBtr0081192(transcript)|ensemblmetazoa:FBtr0342928(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030431"(sleep)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-DME-5689603|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-917937|refseq:NP_001286070.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 rogid:3P7TFMLheJ3IKTDNacGZdCxjrVc7227 intact-crc:26AC97336A1BF44B|rigid:TKG18f9HF7P3LCzzch41GSQCFp0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KTP7 uniprotkb:P40301 intact:EBI-196108|intact:EBI-2111129|intact:EBI-498562|uniprotkb:Q494G2|ensemblmetazoa:FBpp0306241|ensemblmetazoa:FBpp0306242|ensemblmetazoa:FBpp0306243|ensemblmetazoa:FBpp0306244|ensemblmetazoa:FBpp0306245 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:q7ktp7_drome(display_long)|uniprotkb:CG5822(gene name)|psi-mi:CG5822(display_short)|uniprotkb:Dmel\CG44001(gene name synonym)|uniprotkb:CG31919(orf name)|uniprotkb:CG44001(orf name)|uniprotkb:Dmel_CG44001(orf name) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111222|imex:IM-9552-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264743|refseq:NP_001033874.2|refseq:NP_001162882.2|refseq:NP_608900.3|refseq:NP_723051.2|refseq:NP_723052.2|ensemblmetazoa:FBgn0264743(gene)|ensemblmetazoa:FBtr0334124(transcript)|ensemblmetazoa:FBtr0334125(transcript)|ensemblmetazoa:FBtr0334126(transcript)|ensemblmetazoa:FBtr0334127(transcript)|ensemblmetazoa:FBtr0334128(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nmd2MIuypaUtOVbcArZIiNgUULo7227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:32390D1B8985A8FB|rigid:v3Mg0iN4qwjqdkVSNjaB7K8wkDc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:P55035 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111227|imex:IM-9552-322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 intact-crc:9D0D213432AB85C6|rigid:udP12CCeATqtKnivDrnjKT5F9+8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VUR4 uniprotkb:Q27297 intact:EBI-2108311|uniprotkb:D0IQC8|uniprotkb:Q8IQM4|ensemblmetazoa:FBpp0289558|ensemblmetazoa:FBpp0290404 intact:EBI-458769|ensemblmetazoa:FBpp0084955|uniprotkb:Q8IGG8|uniprotkb:Q8IMJ5|uniprotkb:Q9VAA8 psi-mi:q9vur4_drome(display_long)|uniprotkb:Dmel\CG7656(gene name)|psi-mi:Dmel\CG7656(display_short)|uniprotkb:CG7656-RA(gene name synonym)|uniprotkb:CG7656(orf name)|uniprotkb:Dmel_CG7656(orf name) psi-mi:rad51_drome(display_long)|uniprotkb:RecA protein homolog(gene name synonym)|uniprotkb:Protein spindle-A(gene name synonym)|uniprotkb:spn-A(gene name)|psi-mi:spn-A(display_short)|uniprotkb:DMR(gene name synonym)|uniprotkb:Rad51(gene name synonym)|uniprotkb:CG7948(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111217|imex:IM-9552-320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648783.4|refseq:NP_730058.2|flybase:FBgn0036516|ensemblmetazoa:FBgn0036516(gene)|ensemblmetazoa:FBtr0300329(transcript)|ensemblmetazoa:FBtr0301186(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-8866652|reactome:R-DME-983168 ensemblmetazoa:FBgn0003479(gene)|ensemblmetazoa:FBtr0085589(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0009951"(polarity specification of dorsal/ventral axis)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0042148"(strand invasion)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048477"(oogenesis)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-DME-5693616|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|refseq:NP_524583.1|refseq:NP_733342.1|flybase:FBgn0003479|dip:DIP-20846N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:coGA0MXK+GugXCL/79B7bYwsKwM7227 rogid:cI5/t2frneX4xX5x1GmnlrfcIuQ7227 intact-crc:174114645B8BADC9|rigid:omXDuSmaDAWiN7fL9w3IcKgTPrE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWD9 uniprotkb:Q9VCD5 intact:EBI-100499|ensemblmetazoa:FBpp0074519|ensemblmetazoa:FBpp0309477 intact:EBI-139147|ensemblmetazoa:FBpp0083927 psi-mi:q9vwd9_drome(display_long)|uniprotkb:Ubqn(gene name)|psi-mi:Ubqn(display_short)|uniprotkb:CG14224(orf name)|uniprotkb:"BEST:LD26923"(gene name synonym)|uniprotkb:Chap(gene name synonym)|uniprotkb:DSK2(gene name synonym)|uniprotkb:Dmel\CG14224(gene name synonym)|uniprotkb:Dsk2(gene name synonym)|uniprotkb:UBQLN homolog(gene name synonym)|uniprotkb:UBQLN1(gene name synonym)|uniprotkb:anon-18DEa(gene name synonym)|uniprotkb:clone 5.42(gene name synonym)|uniprotkb:dUbqln(gene name synonym)|uniprotkb:dUbqn(gene name synonym)|uniprotkb:ubqn(gene name synonym)|uniprotkb:Dmel_CG14224(orf name)|uniprotkb:dsk2(gene name synonym) psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111232|imex:IM-9552-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608344.1|flybase:FBgn0031057|ensemblmetazoa:FBgn0031057(gene)|ensemblmetazoa:FBtr0074750(transcript)|ensemblmetazoa:FBtr0340612(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|reactome:R-DME-8856825|go:"GO:0005829"(cytosol)|refseq:NP_001285457.1 refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:tyrm7R6Odh66OLSedxkxezyamS07227 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 intact-crc:C27A87B644C99BF3|rigid:vHY7zKpuzwWwcKYAaz/jzi6seUk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VFS8 uniprotkb:Q8SZ19 intact:EBI-166054|ensemblmetazoa:FBpp0082314 intact:EBI-2110884 psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111237|imex:IM-9552-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 intact-crc:FF4DDB723E351AFD|rigid:5ZWI03hUrAvQ97115sP0aNaGtpM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V345 uniprotkb:P40301 intact:EBI-141466|ensemblmetazoa:FBpp0087935|ensemblmetazoa:FBpp0290448|uniprotkb:Q9XYW5 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:csn4_drome(display_long)|uniprotkb:CSN4(gene name)|psi-mi:CSN4(display_short)|uniprotkb:CG8725(orf name) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111257|imex:IM-9552-328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0088859(transcript)|ensemblmetazoa:FBtr0301230(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005829"(cytosol)|ensemblmetazoa:FBgn0027054(gene)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|refseq:NP_001163080.1|refseq:NP_477444.1|flybase:FBgn0027054|dip:DIP-52178N refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Q2daroWgqO7i1NRPR9REIsEOtvo7227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:50B264FB16216085|rigid:IWnjz25lc1wQRr1NqzxRSl5S0YI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:Q9V345 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-141466|ensemblmetazoa:FBpp0087935|ensemblmetazoa:FBpp0290448|uniprotkb:Q9XYW5 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:csn4_drome(display_long)|uniprotkb:CSN4(gene name)|psi-mi:CSN4(display_short)|uniprotkb:CG8725(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111252|imex:IM-9552-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBtr0088859(transcript)|ensemblmetazoa:FBtr0301230(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005829"(cytosol)|ensemblmetazoa:FBgn0027054(gene)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|refseq:NP_001163080.1|refseq:NP_477444.1|flybase:FBgn0027054|dip:DIP-52178N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:Q2daroWgqO7i1NRPR9REIsEOtvo7227 intact-crc:639E4B03C96BFCD6|rigid:dSr4yOhzEdXthBjsNCOLjgKUE+4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWD9 uniprotkb:Q8T6B9 intact:EBI-100499|ensemblmetazoa:FBpp0074519|ensemblmetazoa:FBpp0309477 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 psi-mi:q9vwd9_drome(display_long)|uniprotkb:Ubqn(gene name)|psi-mi:Ubqn(display_short)|uniprotkb:CG14224(orf name)|uniprotkb:"BEST:LD26923"(gene name synonym)|uniprotkb:Chap(gene name synonym)|uniprotkb:DSK2(gene name synonym)|uniprotkb:Dmel\CG14224(gene name synonym)|uniprotkb:Dsk2(gene name synonym)|uniprotkb:UBQLN homolog(gene name synonym)|uniprotkb:UBQLN1(gene name synonym)|uniprotkb:anon-18DEa(gene name synonym)|uniprotkb:clone 5.42(gene name synonym)|uniprotkb:dUbqln(gene name synonym)|uniprotkb:dUbqn(gene name synonym)|uniprotkb:ubqn(gene name synonym)|uniprotkb:Dmel_CG14224(orf name)|uniprotkb:dsk2(gene name synonym) psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111247|imex:IM-9552-326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608344.1|flybase:FBgn0031057|ensemblmetazoa:FBgn0031057(gene)|ensemblmetazoa:FBtr0074750(transcript)|ensemblmetazoa:FBtr0340612(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|reactome:R-DME-8856825|go:"GO:0005829"(cytosol)|refseq:NP_001285457.1 refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:tyrm7R6Odh66OLSedxkxezyamS07227 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 intact-crc:67ECD171F971FE76|rigid:fOHd9sqomitjTULRaezX7qZkO4c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18413 uniprotkb:Q9VFS8 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 intact:EBI-166054|ensemblmetazoa:FBpp0082314 psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111242|imex:IM-9552-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 intact-crc:B85D7301D73C766E|rigid:Z2zooGnQAVDZgPE6NtgoUijD7hA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KTP7 uniprotkb:Q9VK14 intact:EBI-196108|intact:EBI-2111129|intact:EBI-498562|uniprotkb:Q494G2|ensemblmetazoa:FBpp0306241|ensemblmetazoa:FBpp0306242|ensemblmetazoa:FBpp0306243|ensemblmetazoa:FBpp0306244|ensemblmetazoa:FBpp0306245 intact:EBI-166677|ensemblmetazoa:FBpp0080028 psi-mi:q7ktp7_drome(display_long)|uniprotkb:CG5822(gene name)|psi-mi:CG5822(display_short)|uniprotkb:Dmel\CG44001(gene name synonym)|uniprotkb:CG31919(orf name)|uniprotkb:CG44001(orf name)|uniprotkb:Dmel_CG44001(orf name) psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111272|imex:IM-9552-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264743|refseq:NP_001033874.2|refseq:NP_001162882.2|refseq:NP_608900.3|refseq:NP_723051.2|refseq:NP_723052.2|ensemblmetazoa:FBgn0264743(gene)|ensemblmetazoa:FBtr0334124(transcript)|ensemblmetazoa:FBtr0334125(transcript)|ensemblmetazoa:FBtr0334126(transcript)|ensemblmetazoa:FBtr0334127(transcript)|ensemblmetazoa:FBtr0334128(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nmd2MIuypaUtOVbcArZIiNgUULo7227 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 intact-crc:F6670D4B61768E17|rigid:a3HjmmC+iLh490kmNiScQ3V9Iuk false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T6B9 uniprotkb:P15357 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 intact:EBI-414595|ensemblmetazoa:FBpp0079606|uniprotkb:Q9VKW6|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4 psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:rs27a_drome(display_long)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UB3-D(gene name synonym)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG5271(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111267|imex:IM-9552-330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-216167|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5358346|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-538864|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-5607761|reactome:R-DME-6782210|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-5632684|reactome:R-DME-8866652|reactome:R-DME-5654726|reactome:R-DME-8866654|reactome:R-DME-5654727|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-5654732|reactome:R-DME-8941858|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-8948747|reactome:R-DME-5687128|reactome:R-DME-8948751|reactome:R-DME-5689603|reactome:R-DME-8951664|reactome:R-DME-5689877|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168|reactome:R-DME-912631|ensemblmetazoa:FBgn0003942(gene)|ensemblmetazoa:FBtr0080016(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|refseq:NP_476778.1|flybase:FBgn0003942 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 rogid:/TxjkqKvf9HDOWxFySkJFjLFBLM7227 intact-crc:2257CED300E9C89F|rigid:jzoYt2La//QY8IcjOV4If9nmYu8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJJ0 uniprotkb:Q9V345 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 intact:EBI-141466|ensemblmetazoa:FBpp0087935|ensemblmetazoa:FBpp0290448|uniprotkb:Q9XYW5 psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:csn4_drome(display_long)|uniprotkb:CSN4(gene name)|psi-mi:CSN4(display_short)|uniprotkb:CG8725(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111262|imex:IM-9552-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 ensemblmetazoa:FBtr0088859(transcript)|ensemblmetazoa:FBtr0301230(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005829"(cytosol)|ensemblmetazoa:FBgn0027054(gene)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|refseq:NP_001163080.1|refseq:NP_477444.1|flybase:FBgn0027054|dip:DIP-52178N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 rogid:Q2daroWgqO7i1NRPR9REIsEOtvo7227 intact-crc:AF1AE3C9168A320A|rigid:YfO/CL/Rhj/d6jdH21ppUkR7oxE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18413 uniprotkb:Q9VXF9 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111282|imex:IM-9552-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 intact-crc:2F68BA5E9AB51F92|rigid:thLgfGO4ok61T4GHohIAtTiGvYI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:O18640 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-75604|uniprotkb:Q9VLW5|ensemblmetazoa:FBpp0079187|ensemblmetazoa:FBpp0303680|ensemblmetazoa:FBpp0311572 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:gblp_drome(display_long)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:CG7111(orf name)|uniprotkb:Receptor of activated protein kinase C homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111297|imex:IM-9552-336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N refseq:NP_477269.1|flybase:FBgn0020618|refseq:NP_001260218.1|refseq:NP_001285723.1|dip:DIP-17169N|ensemblmetazoa:FBgn0020618(gene)|ensemblmetazoa:FBtr0079565(transcript)|ensemblmetazoa:FBtr0331238(transcript)|ensemblmetazoa:FBtr0345448(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016243"(regulation of autophagosome size)|go:"GO:0018991"(oviposition)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035220"(wing disc development)|go:"GO:0042335"(cuticle development)|go:"GO:0043022"(ribosome binding)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:4V6W psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:nP8EJaYE1rJHjdJ+W2fl6DSQ8JQ7227 intact-crc:44408162DE182284|rigid:Rm+8je/pBq4BqGVTrOfy1eCuvQo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P68198 uniprotkb:P15357 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N intact:EBI-414595|ensemblmetazoa:FBpp0079606|uniprotkb:Q9VKW6|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4 psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:rs27a_drome(display_long)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UB3-D(gene name synonym)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG5271(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111292|imex:IM-9552-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-216167|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5358346|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-538864|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-5607761|reactome:R-DME-6782210|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-5632684|reactome:R-DME-8866652|reactome:R-DME-5654726|reactome:R-DME-8866654|reactome:R-DME-5654727|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-5654732|reactome:R-DME-8941858|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-8948747|reactome:R-DME-5687128|reactome:R-DME-8948751|reactome:R-DME-5689603|reactome:R-DME-8951664|reactome:R-DME-5689877|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168|reactome:R-DME-912631|ensemblmetazoa:FBgn0003942(gene)|ensemblmetazoa:FBtr0080016(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|refseq:NP_476778.1|flybase:FBgn0003942 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 rogid:/TxjkqKvf9HDOWxFySkJFjLFBLM7227 intact-crc:B05495E0996A7688|rigid:zL3PSYUcQQlhbCuUdB7Gn04cpi4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJJ0 uniprotkb:Q9VXF9 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111287|imex:IM-9552-334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 intact-crc:19587D1A598F6DBA|rigid:leoTlw40pbLi98cylsDVBJkoOVg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P92208 uniprotkb:Q7K306 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111277|imex:IM-9552-332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 intact-crc:995119B3725BB453|rigid:DiL0hclH+ft4lpp3Kb5bQfa3RF8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:Q9VJ33 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-90023|uniprotkb:Q29QE5|ensemblmetazoa:FBpp0080733|ensemblmetazoa:FBpp0309711 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:nedd8_drome(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:CG10679(orf name)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111307|imex:IM-9552-338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 refseq:NP_609919.1|flybase:FBgn0032725|ensemblmetazoa:FBgn0032725(gene)|ensemblmetazoa:FBtr0081192(transcript)|ensemblmetazoa:FBtr0342928(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030431"(sleep)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-DME-5689603|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-917937|refseq:NP_001286070.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:3P7TFMLheJ3IKTDNacGZdCxjrVc7227 intact-crc:ABE91B41B7DF4FFB|rigid:Mc7pmzFIUYEastOiVPgGwV7rpOw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VYI0 uniprotkb:Q9VM49 intact:EBI-126770|uniprotkb:Q9NGV0|ensemblmetazoa:FBpp0073543|ensemblmetazoa:FBpp0112400|ensemblmetazoa:FBpp0297664|ensemblmetazoa:FBpp0300900|ensemblmetazoa:FBpp0305511|ensemblmetazoa:FBpp0305512 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 psi-mi:q9vyi0_drome(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)|uniprotkb:fne-RB(gene name synonym)|uniprotkb:"BEST:HL02010"(gene name synonym)|uniprotkb:"BcDNA:HL02010"(gene name synonym)|uniprotkb:"BcDNA:RE25290"(gene name synonym)|uniprotkb:CR32646(gene name synonym)|uniprotkb:Dmel\CG4396(gene name synonym)|uniprotkb:FNE(gene name synonym)|uniprotkb:Fne(gene name synonym)|uniprotkb:MRE28(gene name synonym)|uniprotkb:lincRNA.985(gene name synonym)|uniprotkb:Dmel_CG4396(orf name)|uniprotkb:CG4396(orf name)|uniprotkb:cg4396(gene name synonym) psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111312|imex:IM-9552-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0086675(gene)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979|reactome:R-DME-450520|reactome:R-DME-72163|ensemblmetazoa:FBtr0073712(transcript)|ensemblmetazoa:FBtr0113493(transcript)|ensemblmetazoa:FBtr0306738(transcript)|ensemblmetazoa:FBtr0308694(transcript)|ensemblmetazoa:FBtr0333319(transcript)|ensemblmetazoa:FBtr0333320(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008049"(male courtship behavior)|refseq:NP_001096965.1|refseq:NP_572842.1|flybase:FBgn0086675|refseq:NP_001245646.1|refseq:NP_001245648.1|refseq:NP_001259497.1|refseq:NP_001259498.1 refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:IxfHiln53BTh0NS5caA9LjvUpWc7227 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 intact-crc:683FEFACFFC129B8|rigid:93mpp9aZzkt0+W9Mt1QKOYy/Gjs false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T6B9 uniprotkb:Q9VCD5 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 intact:EBI-139147|ensemblmetazoa:FBpp0083927 psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111302|imex:IM-9552-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 intact-crc:10913F3B3BEA0B0D|rigid:+S7cqMeC5uaVlIL8gD0nnchRdDc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VM49 uniprotkb:O97468 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 intact:EBI-2111069 psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111317|imex:IM-9552-340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 intact-crc:DEFDDEF9BED903BB|rigid:H3BK4Gdzoj8LMapbmy3+guSgkGM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:P48555 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-115197|uniprotkb:Q540X1|ensemblmetazoa:FBpp0070558|ensemblmetazoa:FBpp0070559|uniprotkb:Q9W4Q6 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:rala_drome(display_long)|uniprotkb:Rala(gene name)|psi-mi:Rala(display_short)|uniprotkb:CG2849(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111327|imex:IM-9552-342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N ensemblmetazoa:FBgn0015286(gene)|ensemblmetazoa:FBtr0070583(transcript)|ensemblmetazoa:FBtr0070584(transcript)|go:"GO:0003924"(GTPase activity)|rcsb pdb:5CM9|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0019003"(GDP binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:5CM8|refseq:NP_525063.1|refseq:NP_726882.1|flybase:FBgn0015286|dip:DIP-19199N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:sTSyV5P4zR3/IGjwg6Ov0YFUl6g7227 intact-crc:7CE2AD855911DA2D|rigid:JKTPr2OvclPfG/ORII9lDup2Yvw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O61443 uniprotkb:Q7K306 intact:EBI-82330|ensemblmetazoa:FBpp0080111 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 psi-mi:mk38b_drome(display_long)|uniprotkb:p38b(gene name)|psi-mi:p38b(display_short)|uniprotkb:CG7393(orf name) psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111322|imex:IM-9552-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477361.1|flybase:FBgn0024846|go:"GO:0001934"(positive regulation of protein phosphorylation)|ensemblmetazoa:FBgn0024846(gene)|ensemblmetazoa:FBtr0080534(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009617"(response to bacterium)|go:"GO:0009651"(response to salt stress)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038001"(paracrine signaling)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-168638|reactome:R-DME-171007|reactome:R-DME-198753|reactome:R-DME-2559580|reactome:R-DME-376172|reactome:R-DME-418592|reactome:R-DME-432142|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450341|reactome:R-DME-525793|reactome:R-DME-5675221|reactome:R-DME-6798695|dip:DIP-22779N refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:rkuVJJgL+rmuXx8eEMG3/tjP8tE7227 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 intact-crc:D8D2BE306F4C525F|rigid:sMVSQlOtoWI1LIIBsaKSWMO3rNQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T0S6 uniprotkb:O97468 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 intact:EBI-2111069 psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111332|imex:IM-9552-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 intact-crc:2F9B1A4982B663D8|rigid:rpwMo8Gu3w3b9cX5tkElhsXdiK0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O76460 uniprotkb:P23573 intact:EBI-184970|uniprotkb:B6UXG7|uniprotkb:B6UXH8|uniprotkb:B6UXJ2|uniprotkb:B6UXJ5|uniprotkb:P91636|uniprotkb:Q7K0T1|uniprotkb:Q7KPH9|ensemblmetazoa:FBpp0077357 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:rad54_drome(display_long)|uniprotkb:okr(gene name)|psi-mi:okr(display_short)|uniprotkb:CG3736(orf name)|uniprotkb:RAD54(gene name synonym)|uniprotkb:RAD54 DNA repair protein(gene name synonym)|uniprotkb:Protein okra(gene name synonym) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111342|imex:IM-9552-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476661.1|flybase:FBgn0002989|ensemblmetazoa:FBgn0002989(gene)|ensemblmetazoa:FBtr0077673(transcript)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006417"(regulation of translation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016817"(hydrolase activity, acting on acid anhydrides)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0043150"(DNA synthesis involved in double-strand break repair via homologous recombination)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR013967(Rad54, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718 refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:kHr3FgvM4M3Ge0IcIusTOO7QSl87227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:37DB5B0088E87971|rigid:6fov2OC77IQQyKAs1wpnKcSRcns false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23696 uniprotkb:Q9VM49 intact:EBI-101960|uniprotkb:Q9VLW4|ensemblmetazoa:FBpp0079148|ensemblmetazoa:FBpp0310062|ensemblmetazoa:FBpp0310063 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 psi-mi:pp2a_drome(display_long)|uniprotkb:mts(gene name)|psi-mi:mts(display_short)|uniprotkb:PP2A(gene name synonym)|uniprotkb:Pp2A-28D(gene name synonym)|uniprotkb:CG7109(orf name)|uniprotkb:Protein microtubule star(gene name synonym) psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111337|imex:IM-9552-344 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0009416"(response to light stimulus)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-DME-1295596|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-2995383|reactome:R-DME-389513|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-432626|reactome:R-DME-5673000|reactome:R-DME-5675221|reactome:R-DME-6811558|reactome:R-DME-69231|reactome:R-DME-69273|reactome:R-DME-975957|refseq:NP_001285724.1|refseq:NP_001285725.1|refseq:NP_476805.1|flybase:FBgn0004177|ensemblmetazoa:FBgn0004177(gene)|ensemblmetazoa:FBtr0079525(transcript)|ensemblmetazoa:FBtr0343416(transcript)|ensemblmetazoa:FBtr0343417(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|dip:DIP-17814N refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VLIsr3gJAP9LjcDE+7++cPMfs3A7227 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 intact-crc:D67535DEBB6FA22A|rigid:86bzQvUUVG4wqqAThOiBWygIUDY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P22769 uniprotkb:Q8T6B9 intact:EBI-93148|uniprotkb:Q9VXI9|ensemblmetazoa:FBpp0073989 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 psi-mi:psa71_drome(display_long)|uniprotkb:Prosalpha4(gene name)|psi-mi:Prosalpha4(display_short)|uniprotkb:PROS-28.1(gene name synonym)|uniprotkb:PROS-Dm28.1(gene name synonym)|uniprotkb:Pros28.1(gene name synonym)|uniprotkb:Proteasome 28 kDa subunit 1(gene name synonym)|uniprotkb:CG3422(orf name) psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111347|imex:IM-9552-346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525092.1|flybase:FBgn0004066|ensemblmetazoa:FBgn0004066(gene)|ensemblmetazoa:FBtr0074210(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-69601|reactome:R-DME-69017|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-450408|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-4608870|reactome:R-DME-432395|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|dip:DIP-17376N refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:gQpRF01CDAsvV4Rc2YSFf8drjtY7227 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 intact-crc:E412DA62AC6A0122|rigid:dRq3OZaMGPPCgkh2VVFgLB1t0I0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VM49 uniprotkb:Q24133 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 intact:EBI-87640|uniprotkb:Q9VRP0|ensemblmetazoa:FBpp0076829|ensemblmetazoa:FBpp0076830 psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:dnaj1_drome(display_long)|uniprotkb:DnaJ-1(gene name)|psi-mi:DnaJ-1(display_short)|uniprotkb:DROJ1(gene name synonym)|uniprotkb:CG10578(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111357|imex:IM-9552-348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 refseq:NP_523936.2|refseq:NP_729086.1|ensemblmetazoa:FBgn0263106(gene)|ensemblmetazoa:FBtr0077123(transcript)|ensemblmetazoa:FBtr0077124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009408"(response to heat)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|flybase:FBgn0263106|dip:DIP-18469N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 rogid:a9IH3J+QRKijRMBTudpvE5YV/Ek7227 intact-crc:9B001341424E01E3|rigid:nhXlgs02lsglt/IBJscLVrQxA/s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXF9 uniprotkb:P68198 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111362|imex:IM-9552-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 intact-crc:A17ECC270BDF8A91|rigid:LEHkq9nf0t1tKOvU7afZY4QCn6s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:P15357 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-414595|ensemblmetazoa:FBpp0079606|uniprotkb:Q9VKW6|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:rs27a_drome(display_long)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UB3-D(gene name synonym)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG5271(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111367|imex:IM-9552-350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-216167|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5358346|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-538864|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-5607761|reactome:R-DME-6782210|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-5632684|reactome:R-DME-8866652|reactome:R-DME-5654726|reactome:R-DME-8866654|reactome:R-DME-5654727|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-5654732|reactome:R-DME-8941858|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-8948747|reactome:R-DME-5687128|reactome:R-DME-8948751|reactome:R-DME-5689603|reactome:R-DME-8951664|reactome:R-DME-5689877|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168|reactome:R-DME-912631|ensemblmetazoa:FBgn0003942(gene)|ensemblmetazoa:FBtr0080016(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|refseq:NP_476778.1|flybase:FBgn0003942 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:/TxjkqKvf9HDOWxFySkJFjLFBLM7227 intact-crc:F13D9744689FA12C|rigid:CDO6MZNtC6KNKEh+9v1xyYfGz70 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:P68198 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111372|imex:IM-9552-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 intact-crc:38B0DA9B4D8E65C9|rigid:fjV8VCFCYKo0WtLveUggxDDZCz0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VM49 uniprotkb:Q7JN15 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 intact:EBI-2111140|ensemblmetazoa:FBpp0084256 psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:q7jn15_drome(display_long)|uniprotkb:msi(gene name)|psi-mi:msi(display_short)|uniprotkb:CG5099(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111352|imex:IM-9552-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 flybase:FBgn0011666|ensemblmetazoa:FBgn0011666(gene)|ensemblmetazoa:FBtr0084882(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0001709"(cell fate determination)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022416"(chaeta development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 rogid:nl81bRYxT/uQS/uagdpSq92reJg7227 intact-crc:19979A88641013E4|rigid:LAPiTH7pUcav3wis5V1EUWnE8Io false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VXF9 uniprotkb:Q8T6B9 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111382|imex:IM-9552-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 intact-crc:253010FBE1B6D1E1|rigid:BuCRbtWtVQ59fOF3JK0bvl/K2/Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:P23696 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-101960|uniprotkb:Q9VLW4|ensemblmetazoa:FBpp0079148|ensemblmetazoa:FBpp0310062|ensemblmetazoa:FBpp0310063 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:pp2a_drome(display_long)|uniprotkb:mts(gene name)|psi-mi:mts(display_short)|uniprotkb:PP2A(gene name synonym)|uniprotkb:Pp2A-28D(gene name synonym)|uniprotkb:CG7109(orf name)|uniprotkb:Protein microtubule star(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111377|imex:IM-9552-352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0009416"(response to light stimulus)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-DME-1295596|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-2995383|reactome:R-DME-389513|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-432626|reactome:R-DME-5673000|reactome:R-DME-5675221|reactome:R-DME-6811558|reactome:R-DME-69231|reactome:R-DME-69273|reactome:R-DME-975957|refseq:NP_001285724.1|refseq:NP_001285725.1|refseq:NP_476805.1|flybase:FBgn0004177|ensemblmetazoa:FBgn0004177(gene)|ensemblmetazoa:FBtr0079525(transcript)|ensemblmetazoa:FBtr0343416(transcript)|ensemblmetazoa:FBtr0343417(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|dip:DIP-17814N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:VLIsr3gJAP9LjcDE+7++cPMfs3A7227 intact-crc:EA5A56B60FE56FD3|rigid:CnIn4yX6miUQlyBVCJSQdVF1FiE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T6B9 uniprotkb:P23573 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111387|imex:IM-9552-354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:F5C0114194804E5B|rigid:LPtfNFIOl/6hVxPxZYgTdxDkm8E false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P10987 uniprotkb:O46085 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 intact:EBI-151469|uniprotkb:Q8MSJ5|ensemblmetazoa:FBpp0070351 psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:o46085_drome(display_long)|uniprotkb:Pex5(gene name)|psi-mi:Pex5(display_short)|uniprotkb:"EG:63B12.5"(gene name synonym)|uniprotkb:arm(gene name synonym)|uniprotkb:Dmel_CG14815(orf name)|uniprotkb:DmelPex5(gene name synonym)|uniprotkb:Dmel\CG14815(gene name synonym)|uniprotkb:PEX5(gene name synonym)|uniprotkb:CG14815(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111392|imex:IM-9552-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N refseq:NP_726771.1|flybase:FBgn0023516|ensemblmetazoa:FBgn0023516(gene)|ensemblmetazoa:FBtr0070367(transcript)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0072347"(response to anesthetic)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|reactome:R-DME-8866654|reactome:R-DME-9033241 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 rogid:6VHzfzaHUVyCneNbSNqPM/sf1Rs7227 intact-crc:9850C860E441A00D|rigid:gwpNxWdNUwOdJWZYA/gFeS1ya6A false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q9VUQ8 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-128574|intact:EBI-1630096|ensemblmetazoa:FBpp0075314|ensemblmetazoa:FBpp0304267 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:dcn1l_drome(display_long)|uniprotkb:CG7427(orf name)|uniprotkb:Defective in cullin neddylation protein 1-like protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111397|imex:IM-9552-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_648777.1|flybase:FBgn0036510|ensemblmetazoa:FBgn0036510(gene)|ensemblmetazoa:FBtr0075561(transcript)|ensemblmetazoa:FBtr0331934(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0045116"(protein neddylation)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000436"(positive regulation of protein neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR009060(UBA-like)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|reactome:R-DME-8951664|refseq:NP_001261883.1|dip:DIP-19770N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:AnSMu7CvBo1zzXRpAnD684a6+E07227 intact-crc:B31A7834F2CAC7AC|rigid:StJAlhgjVJP6DVvyE8NN6tr+ZEw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O76460 uniprotkb:O18413 intact:EBI-184970|uniprotkb:B6UXG7|uniprotkb:B6UXH8|uniprotkb:B6UXJ2|uniprotkb:B6UXJ5|uniprotkb:P91636|uniprotkb:Q7K0T1|uniprotkb:Q7KPH9|ensemblmetazoa:FBpp0077357 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:rad54_drome(display_long)|uniprotkb:okr(gene name)|psi-mi:okr(display_short)|uniprotkb:CG3736(orf name)|uniprotkb:RAD54(gene name synonym)|uniprotkb:RAD54 DNA repair protein(gene name synonym)|uniprotkb:Protein okra(gene name synonym) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111402|imex:IM-9552-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476661.1|flybase:FBgn0002989|ensemblmetazoa:FBgn0002989(gene)|ensemblmetazoa:FBtr0077673(transcript)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006417"(regulation of translation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016817"(hydrolase activity, acting on acid anhydrides)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0043150"(DNA synthesis involved in double-strand break repair via homologous recombination)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR013967(Rad54, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718 refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:kHr3FgvM4M3Ge0IcIusTOO7QSl87227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:209268F86A574863|rigid:wCjUB8D8WAvl80csIG5mI4nIpDI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P49071 intact:EBI-185748 intact:EBI-118687|uniprotkb:Q9W480|ensemblmetazoa:FBpp0070802|ensemblmetazoa:FBpp0070804|ensemblmetazoa:FBpp0292066|ensemblmetazoa:FBpp0300801 intact:EBI-2111417 psi-mi:mapk2_drome(display_long)|uniprotkb:MAPk-Ak2(gene name)|psi-mi:MAPk-Ak2(display_short)|uniprotkb:CG3086(orf name) psi-mi:a1za66_drome(display_short)|psi-mi:EBI-185748(display_long)|uniprotkb:Strn-Mlck(gene name)|psi-mi:Strn-Mlck(display_short)|uniprotkb:Dmel_CG18255(orf name)|uniprotkb:CG15699(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111431|imex:IM-9552-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001188547.1|refseq:NP_524769.1|refseq:NP_788861.1|flybase:FBgn0013987|ensemblmetazoa:FBgn0013987(gene)|ensemblmetazoa:FBtr0070837(transcript)|ensemblmetazoa:FBtr0070839(transcript)|ensemblmetazoa:FBtr0302940(transcript)|ensemblmetazoa:FBtr0308577(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009651"(response to salt stress)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0051019"(mitogen-activated protein kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|reactome:R-DME-171007|reactome:R-DME-199920|reactome:R-DME-2559580|reactome:R-DME-3371453|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450385|reactome:R-DME-450513|refseq:NP_001245536.1|dip:DIP-21714N uniprotkb:A1ZA66(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jOgW9S5IhMsBz2vBME8MBe9CyQI7227 rogid:nal5Fum2kMZEiuTkkXXGGZXf/4Q7227 intact-crc:203627CC9624CA0A|rigid:Wv9/Xh4zPENECUaK9R5gk8mEef0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:Q8T0S6 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111407|imex:IM-9552-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 intact-crc:820FE3F4A7AA82BE|rigid:1Imei2qmBJmLM4Haj/sTctP5HOU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P31409 uniprotkb:P23573 intact:EBI-198835|uniprotkb:Q53YH8|uniprotkb:Q9VG52|ensemblmetazoa:FBpp0082139|ensemblmetazoa:FBpp0082140|ensemblmetazoa:FBpp0290875 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:vatb_drome(display_long)|uniprotkb:Vha55(gene name)|psi-mi:Vha55(display_short)|uniprotkb:CG17369(orf name)|uniprotkb:Vacuolar proton pump subunit B(gene name synonym)|uniprotkb:V-ATPase 55 kDa subunit(gene name synonym) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111412|imex:IM-9552-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163597.1|refseq:NP_476908.1|refseq:NP_731726.1|flybase:FBgn0005671|dip:DIP-17495N|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016787"(hydrolase activity)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|reactome:R-DME-1222556|reactome:R-DME-77387|reactome:R-DME-917977|reactome:R-DME-9639288|reactome:R-DME-983712|ensemblmetazoa:FBgn0005671(gene)|ensemblmetazoa:FBtr0082670(transcript)|ensemblmetazoa:FBtr0082671(transcript)|ensemblmetazoa:FBtr0301661(transcript) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:KBtajc3ZD825Z5cbJUt8QmsEdBo7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:12DC0A0006EE3658|rigid:PfrGpBh0f6RTlm9gAieH1AU0c0k false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:A1Z866 uniprotkb:Q8SWQ9 intact:EBI-148231|intact:EBI-2111446|ensemblmetazoa:FBpp0087427 intact:EBI-2111454 psi-mi:a1z866_drome(display_long)|uniprotkb:CAP(gene name)|psi-mi:CAP(display_short)|uniprotkb:CG18409(gene name synonym)|uniprotkb:CG3451(gene name synonym)|uniprotkb:DCAP(gene name synonym)|uniprotkb:Dmel\CG18408(gene name synonym)|uniprotkb:Rexin(gene name synonym)|uniprotkb:Vinexin(gene name synonym)|uniprotkb:cap(gene name synonym)|uniprotkb:rexin(gene name synonym)|uniprotkb:CG18408(orf name)|uniprotkb:Dmel_CG18408(orf name) psi-mi:q8swq9_drome(display_long)|uniprotkb:Arts(gene name)|psi-mi:Arts(display_short)|uniprotkb:CG18861(gene name synonym)|uniprotkb:CG32164(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111451|imex:IM-9552-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610570.1|flybase:FBgn0033504|ensemblmetazoa:FBgn0033504(gene)|ensemblmetazoa:FBtr0088338(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0050954"(sensory perception of mechanical stimulus)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR036028 flybase:FBgn0042177|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:XEN75brprHfY4ZLb++9fGgcMr3A7227 rogid:WNBnfyUp0uS2+0TiY57AstOCTOA7227 intact-crc:1CED032212B4A67E|rigid:7ly3G0J9yQ+YOn+zzR0O4ykFWlY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P68198 uniprotkb:Q9W418 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N intact:EBI-114005|ensemblmetazoa:FBpp0070894|ensemblmetazoa:FBpp0311816 psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:q9w418_drome(display_long)|uniprotkb:Ubi-p5E(gene name)|psi-mi:Ubi-p5E(display_short)|uniprotkb:CG32744(orf name)|uniprotkb:CG18282(gene name synonym)|uniprotkb:CR32744(gene name synonym)|uniprotkb:DmUbi-p5E(gene name synonym)|uniprotkb:Dmel\CG32744(gene name synonym)|uniprotkb:UB(gene name synonym)|uniprotkb:Ub(gene name synonym)|uniprotkb:Ubi(gene name synonym)|uniprotkb:Ubiq(gene name synonym)|uniprotkb:Dmel_CG32744(orf name)|uniprotkb:DmUb(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111436|imex:IM-9552-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 ensemblmetazoa:FBgn0086558(gene)|ensemblmetazoa:FBtr0070933(transcript)|ensemblmetazoa:FBtr0345892(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|reactome:R-DME-5607761|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5358346|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689877|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-912631|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-983168|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948747|interpro:IPR019956|reactome:R-DME-195253|interpro:IPR029071|reactome:R-DME-201681|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-2173788|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-174048|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-382556|reactome:R-DME-174178|reactome:R-DME-450408|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-4608870|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|refseq:NP_727078.1|flybase:FBgn0086558|refseq:NP_001284937.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 rogid:Nji68Fj8jQXcZi1dmH2WkapaGFU7227 intact-crc:1A79786E560E8CEF|rigid:sGZiffqp7aTJusMDez+bEt+iEeU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:Q7KRR5 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-132908|uniprotkb:Q8IGW3|uniprotkb:Q8MRV8|intact:EBI-1437765|uniprotkb:Q9NBD5|uniprotkb:Q9V9J5|ensemblmetazoa:FBpp0085325|ensemblmetazoa:FBpp0307273 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:ngly1_drome(display_long)|uniprotkb:Pngl(gene name)|psi-mi:Pngl(display_short)|uniprotkb:CG7865(orf name)|uniprotkb:PNGase(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111441|imex:IM-9552-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 flybase:FBgn0033050|refseq:NP_610192.1|refseq:NP_724444.3|ensemblmetazoa:FBgn0033050(gene)|ensemblmetazoa:FBtr0085972(transcript)|ensemblmetazoa:FBtr0335285(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0007495"(visceral mesoderm-endoderm interaction involved in midgut development)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR002931(Transglutaminase-like)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|reactome:R-DME-532668 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2016/02/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:HEl/Dre+506bWoUEYNvetbXWsQY7227 intact-crc:750470EEDD247CD2|rigid:6f4M9XJNlIYpNKJRQkWzexEkWtg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T4A6 uniprotkb:Q24133 intact:EBI-2111146 intact:EBI-87640|uniprotkb:Q9VRP0|ensemblmetazoa:FBpp0076829|ensemblmetazoa:FBpp0076830 psi-mi:q8t4a6_drome(display_long)|uniprotkb:CG12782(orf name) psi-mi:dnaj1_drome(display_long)|uniprotkb:DnaJ-1(gene name)|psi-mi:DnaJ-1(display_short)|uniprotkb:DROJ1(gene name synonym)|uniprotkb:CG10578(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111476|imex:IM-9552-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0034838|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037631 refseq:NP_523936.2|refseq:NP_729086.1|ensemblmetazoa:FBgn0263106(gene)|ensemblmetazoa:FBtr0077123(transcript)|ensemblmetazoa:FBtr0077124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009408"(response to heat)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|flybase:FBgn0263106|dip:DIP-18469N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:zzzD7GjR9hAU1T05SZnQDywdDoY7227 rogid:a9IH3J+QRKijRMBTudpvE5YV/Ek7227 intact-crc:FC826EDBF41D178A|rigid:iJkmpyO8uD2Y8cMfP9q57MmM7zI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VCD5 uniprotkb:Q9VFS8 intact:EBI-139147|ensemblmetazoa:FBpp0083927 intact:EBI-166054|ensemblmetazoa:FBpp0082314 psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111461|imex:IM-9552-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 intact-crc:17938F631187DD98|rigid:VL191S66RkGXyOLb0hmOzInpDHA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O46085 uniprotkb:Q9V345 intact:EBI-151469|uniprotkb:Q8MSJ5|ensemblmetazoa:FBpp0070351 intact:EBI-141466|ensemblmetazoa:FBpp0087935|ensemblmetazoa:FBpp0290448|uniprotkb:Q9XYW5 psi-mi:o46085_drome(display_long)|uniprotkb:Pex5(gene name)|psi-mi:Pex5(display_short)|uniprotkb:"EG:63B12.5"(gene name synonym)|uniprotkb:arm(gene name synonym)|uniprotkb:Dmel_CG14815(orf name)|uniprotkb:DmelPex5(gene name synonym)|uniprotkb:Dmel\CG14815(gene name synonym)|uniprotkb:PEX5(gene name synonym)|uniprotkb:CG14815(orf name) psi-mi:csn4_drome(display_long)|uniprotkb:CSN4(gene name)|psi-mi:CSN4(display_short)|uniprotkb:CG8725(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111466|imex:IM-9552-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726771.1|flybase:FBgn0023516|ensemblmetazoa:FBgn0023516(gene)|ensemblmetazoa:FBtr0070367(transcript)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0072347"(response to anesthetic)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|reactome:R-DME-8866654|reactome:R-DME-9033241 ensemblmetazoa:FBtr0088859(transcript)|ensemblmetazoa:FBtr0301230(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005829"(cytosol)|ensemblmetazoa:FBgn0027054(gene)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|refseq:NP_001163080.1|refseq:NP_477444.1|flybase:FBgn0027054|dip:DIP-52178N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6VHzfzaHUVyCneNbSNqPM/sf1Rs7227 rogid:Q2daroWgqO7i1NRPR9REIsEOtvo7227 intact-crc:5392237AB0B6CB33|rigid:tMX+SVsFS5hWnAGnhHxdZeKo/HU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23128-1 uniprotkb:P23573 intact:EBI-1012355|ensemblmetazoa:FBpp0079565 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:p23128-1(display_long)|uniprotkb:me31B(gene name)|psi-mi:me31B(display_short)|uniprotkb:Maternal expression at 31B(gene name synonym)|uniprotkb:CG4916(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111471|imex:IM-9552-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-300281(me31_drome)|ensemblmetazoa:FBtr0079975(transcript)|ensemblmetazoa:FBgn0004419(gene) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:qN9bybi82EScbklfgAdPnCZV/G07227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:1D9C3C55F7A54D9D|rigid:6mQTPqkiGtwsvay+pLKa7qpuoe4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:Q8SZ19 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-2110884 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111481|imex:IM-9552-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 intact-crc:4E8E0DB0C0B94E24|rigid:omQXdwzgCFWWvcZchfcoUW5ULa4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:Q961D1 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-130995|intact:EBI-1627566|ensemblmetazoa:FBpp0085295|ensemblmetazoa:FBpp0085296|ensemblmetazoa:FBpp0310472 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:q961d1_drome(display_long)|uniprotkb:CycK(gene name)|psi-mi:CycK(display_short)|uniprotkb:Dmel\CG15218(gene name synonym)|uniprotkb:Dmel_CG15218(orf name)|uniprotkb:CG15218(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111486|imex:IM-9552-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N refseq:NP_788082.1|refseq:NP_788083.1|flybase:FBgn0025674|refseq:NP_001286131.1|ensemblmetazoa:FBgn0025674(gene)|ensemblmetazoa:FBtr0085941(transcript)|ensemblmetazoa:FBtr0085942(transcript)|ensemblmetazoa:FBtr0344022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR043198|reactome:R-DME-112382|reactome:R-DME-2173796|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-6807505|reactome:R-DME-75955 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:rtBGl87kQqd6PG6He8rlKV1Z2DI7227 intact-crc:B879217BDE2B8A5E|rigid:63xPutfEO2Vi30RvKm1pSINtx2w false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q24159 uniprotkb:P23573 intact:EBI-455799|intact:EBI-1629390 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:q24159_drome(display_long)|uniprotkb:CycJ(gene name)|psi-mi:CycJ(display_short)|uniprotkb:CG10308(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111491|imex:IM-9552-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010317|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0060966"(regulation of gene silencing by RNA)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361 refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:v0+u1HylNkW8beHZZmGfAIjkczo7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:B42615B6179F6541|rigid:CLKkZwct3U4X1B0pfglUfHlxzN8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KMQ0 uniprotkb:O18413 intact:EBI-106192|intact:EBI-1629664|ensemblmetazoa:FBpp0088021 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:q7kmq0_drome(display_long)|uniprotkb:Rpt1(gene name)|psi-mi:Rpt1(display_short)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:1341(gene name synonym)|uniprotkb:Dm_Rpt1(gene name synonym)|uniprotkb:Dmel\CG1341(gene name synonym)|uniprotkb:Dmp48B(gene name synonym)|uniprotkb:Q7KMQ0_DROME(gene name synonym)|uniprotkb:S7(gene name synonym)|uniprotkb:anon-WO0118547.90(gene name synonym)|uniprotkb:dRpt1(gene name synonym)|uniprotkb:"l(2)05643"(gene name synonym)|uniprotkb:"l(2)43Ed"(gene name synonym)|uniprotkb:p48B(gene name synonym)|uniprotkb:CG1341(orf name)|uniprotkb:Dmel_CG1341(orf name) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111506|imex:IM-9552-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477473.1|flybase:FBgn0028687|ensemblmetazoa:FBgn0028687(gene)|ensemblmetazoa:FBtr0088947(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+9sRlHY81SOE7UTwGX3JsdHiN807227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:A0456AF0671756C5|rigid:PFOSkLIW88WuxtVaLrhOlIq8xxY false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VCZ8 uniprotkb:Q9VTE5 intact:EBI-100243|ensemblmetazoa:FBpp0083650|ensemblmetazoa:FBpp0290701 intact:EBI-112583|uniprotkb:C6SV13|ensemblmetazoa:FBpp0075967|ensemblmetazoa:FBpp0304954 psi-mi:pfd5_drome(display_long)|uniprotkb:Pfdn5(gene name)|psi-mi:Pfdn5(display_short)|uniprotkb:CG7048(orf name) psi-mi:pfd2_drome(display_long)|uniprotkb:Pfdn2(gene name)|psi-mi:Pfdn2(display_short)|uniprotkb:"l(3)01239"(gene name synonym)|uniprotkb:CG6302(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111496|imex:IM-9552-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163688.1|refseq:NP_651053.1|flybase:FBgn0038976|ensemblmetazoa:FBtr0084257(transcript)|ensemblmetazoa:FBtr0301486(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|ensemblmetazoa:FBgn0038976(gene)|dip:DIP-20776N refseq:NP_729659.1|flybase:FBgn0010741|refseq:NP_001261696.1|dip:DIP-22191N|ensemblmetazoa:FBgn0010741(gene)|ensemblmetazoa:FBtr0076238(transcript)|ensemblmetazoa:FBtr0332708(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045196"(establishment or maintenance of neuroblast polarity)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:R01L4ZDGwNZuXw+pXbvc9E2wzDs7227 rogid:ccPPMbwX2DWNB1xHVoFjzMiyJ/o7227 intact-crc:430291BADF1E878D|rigid:LQeWMk0OT8mJ1xkyFGqLoU8ol1Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KMQ0 uniprotkb:P48601 intact:EBI-106192|intact:EBI-1629664|ensemblmetazoa:FBpp0088021 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q7kmq0_drome(display_long)|uniprotkb:Rpt1(gene name)|psi-mi:Rpt1(display_short)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:1341(gene name synonym)|uniprotkb:Dm_Rpt1(gene name synonym)|uniprotkb:Dmel\CG1341(gene name synonym)|uniprotkb:Dmp48B(gene name synonym)|uniprotkb:Q7KMQ0_DROME(gene name synonym)|uniprotkb:S7(gene name synonym)|uniprotkb:anon-WO0118547.90(gene name synonym)|uniprotkb:dRpt1(gene name synonym)|uniprotkb:"l(2)05643"(gene name synonym)|uniprotkb:"l(2)43Ed"(gene name synonym)|uniprotkb:p48B(gene name synonym)|uniprotkb:CG1341(orf name)|uniprotkb:Dmel_CG1341(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111501|imex:IM-9552-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477473.1|flybase:FBgn0028687|ensemblmetazoa:FBgn0028687(gene)|ensemblmetazoa:FBtr0088947(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:+9sRlHY81SOE7UTwGX3JsdHiN807227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:2A4C803F72AC30C1|rigid:hUSQ3AIObhxI+FM1INyYnqdE2bw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q95083 uniprotkb:P40301 intact:EBI-142547|uniprotkb:Q0E942|uniprotkb:Q9V809|ensemblmetazoa:FBpp0086066|ensemblmetazoa:FBpp0086067 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:psa5_drome(display_long)|uniprotkb:Prosalpha5(gene name)|psi-mi:Prosalpha5(display_short)|uniprotkb:CG10938(orf name)|uniprotkb:ProsMA5(gene name synonym) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111531|imex:IM-9552-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477202.2|refseq:NP_725669.1|flybase:FBgn0016697|dip:DIP-19014N|ensemblmetazoa:FBgn0016697(gene)|ensemblmetazoa:FBtr0086910(transcript)|ensemblmetazoa:FBtr0086911(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-6798695|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Mgpi6YTS79PfgUmLLUXK57ANOq07227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:18A3139A44CE6A28|rigid:IR+JGloVq3oirPpZdMczUcpuGYc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:Q7KMQ0 intact:EBI-2110884 intact:EBI-106192|intact:EBI-1629664|ensemblmetazoa:FBpp0088021 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:q7kmq0_drome(display_long)|uniprotkb:Rpt1(gene name)|psi-mi:Rpt1(display_short)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:1341(gene name synonym)|uniprotkb:Dm_Rpt1(gene name synonym)|uniprotkb:Dmel\CG1341(gene name synonym)|uniprotkb:Dmp48B(gene name synonym)|uniprotkb:Q7KMQ0_DROME(gene name synonym)|uniprotkb:S7(gene name synonym)|uniprotkb:anon-WO0118547.90(gene name synonym)|uniprotkb:dRpt1(gene name synonym)|uniprotkb:"l(2)05643"(gene name synonym)|uniprotkb:"l(2)43Ed"(gene name synonym)|uniprotkb:p48B(gene name synonym)|uniprotkb:CG1341(orf name)|uniprotkb:Dmel_CG1341(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111526|imex:IM-9552-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_477473.1|flybase:FBgn0028687|ensemblmetazoa:FBgn0028687(gene)|ensemblmetazoa:FBtr0088947(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:+9sRlHY81SOE7UTwGX3JsdHiN807227 intact-crc:FA3C07CEAF53EAAB|rigid:MpdN8hKcDlD6s/sbBXguiH61bX8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q8SZ19 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-2110884 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111511|imex:IM-9552-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 intact-crc:246FE71BC89DD03F|rigid:puYtAk7JNGe9c1t3XzDLl4WDIuM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJJ0 uniprotkb:P48601 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111516|imex:IM-9552-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:C50828DAAC132CC4|rigid:pKV6eJziaGWn027J5VlrfqGAkf4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:Q9VJJ0 intact:EBI-2110884 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111521|imex:IM-9552-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:08116A6650A12653|rigid:KFCyrvUUh1/SQ0XtxPmXO2zh9vg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KNM2 uniprotkb:O97102 intact:EBI-74966|intact:EBI-1627711|ensemblmetazoa:FBpp0077741|ensemblmetazoa:FBpp0077742|ensemblmetazoa:FBpp0301731|ensemblmetazoa:FBpp0301732 intact:EBI-114439|ensemblmetazoa:FBpp0078984|ensemblmetazoa:FBpp0312327 psi-mi:q7knm2_drome(display_long)|uniprotkb:lwr(gene name)|psi-mi:lwr(display_short)|uniprotkb:semi(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:DUbc9(gene name synonym)|uniprotkb:DmUbc9(gene name synonym)|uniprotkb:Dmel\CG3018(gene name synonym)|uniprotkb:Dmubc9(gene name synonym)|uniprotkb:FBgn0010602(gene name synonym)|uniprotkb:Iwr(gene name synonym)|uniprotkb:Lwr(gene name synonym)|uniprotkb:Ubc 9(gene name synonym)|uniprotkb:Ubc-9(gene name synonym)|uniprotkb:UbcD9(gene name synonym)|uniprotkb:dUBC9(gene name synonym)|uniprotkb:dUbc9(gene name synonym)|uniprotkb:dip4(gene name synonym)|uniprotkb:hbl(gene name synonym)|uniprotkb:i105(gene name synonym)|uniprotkb:i56(gene name synonym)|uniprotkb:"l(2)01519"(gene name synonym)|uniprotkb:"l(2)02858"(gene name synonym)|uniprotkb:"l(2)05486"(gene name synonym)|uniprotkb:"l(2)05487"(gene name synonym)|uniprotkb:ubc9(gene name synonym)|uniprotkb:Dmel_CG3018(orf name)|uniprotkb:UBC9(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:CG3018(orf name) psi-mi:o97102_drome(display_long)|uniprotkb:smt3(gene name)|psi-mi:smt3(display_short)|uniprotkb:Smt3(gene name synonym)|uniprotkb:DmSUMO-1(gene name synonym)|uniprotkb:Dm0342(gene name synonym)|uniprotkb:DmSmt3(gene name synonym)|uniprotkb:Dmel\CG4494(gene name synonym)|uniprotkb:Dmsmt3(gene name synonym)|uniprotkb:SMT3(gene name synonym)|uniprotkb:SUMO(gene name synonym)|uniprotkb:Sumo(gene name synonym)|uniprotkb:"anon-EST:Posey240"(gene name synonym)|uniprotkb:dSmt3(gene name synonym)|uniprotkb:dsmt3(gene name synonym)|uniprotkb:"l(2)04493"(gene name synonym)|uniprotkb:"l(2)SH0182"(gene name synonym)|uniprotkb:"l(2)SH2 0182"(gene name synonym)|uniprotkb:CG4494(orf name)|uniprotkb:sumo(gene name synonym)|uniprotkb:Dmel_CG4494(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111546|imex:IM-9552-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476978.1|refseq:NP_722637.1|flybase:FBgn0010602|refseq:NP_001259833.1|refseq:NP_001259834.1|ensemblmetazoa:FBgn0010602(gene)|ensemblmetazoa:FBtr0078081(transcript)|ensemblmetazoa:FBtr0078082(transcript)|ensemblmetazoa:FBtr0310028(transcript)|ensemblmetazoa:FBtr0310029(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000940"(outer kinetochore)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007391"(dorsal closure)|go:"GO:0008354"(germ cell migration)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035207"(negative regulation of hemocyte proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140540"(negative regulation melanotic encapsulation of foreign target)|go:"GO:1904677"(positive regulation of somatic stem cell division)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-196791|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395 refseq:NP_477411.1|go:"GO:0000940"(outer kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|ensemblmetazoa:FBgn0264922(gene)|ensemblmetazoa:FBtr0079356(transcript)|ensemblmetazoa:FBtr0346716(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030496"(midbody)|go:"GO:0031386"(protein tag)|go:"GO:0035073"(pupariation)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:O97102|rcsb pdb:2K1F|reactome:R-DME-196791|reactome:R-DME-3065679|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395|refseq:NP_001303312.1|flybase:FBgn0264922 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0klFCJX3ACVlfPFXyh4vl9degjM7227 rogid:fqo3Y86DDI0SsWGEfanaOs8qJlk7227 intact-crc:50E8668E86F4DB9B|rigid:6/XhKmZd3GMSgwlBGdCFvobSCo0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:Q9V5C6 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111536|imex:IM-9552-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 intact-crc:ADF2CFFBF1649DCF|rigid:qVxX63mLEx2xZtEkGkRjsRATv/M false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IRD1 uniprotkb:Q9VJJ0 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111541|imex:IM-9552-380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:5510DCDBA12B97EF|rigid:qp5CH9D+htubnRV6RoSGe2NLH6Y false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9VK14 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-166677|ensemblmetazoa:FBpp0080028 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111561|imex:IM-9552-384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 intact-crc:BDAACAEBCC2C388B|rigid:c18kIKApicU4cQilQVRnjzTLUbc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:Q9VJJ0 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111566|imex:IM-9552-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:32BFC898C5E7B0F4|rigid:kVvxIMO5RIJYz8hIRLeNxQi3LHA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VK14 uniprotkb:P48601 intact:EBI-166677|ensemblmetazoa:FBpp0080028 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111551|imex:IM-9552-382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:8E86E5131366A4D8|rigid:Vg/LwjUJgQrnGLMcp05BVX2PmtU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IRD1 uniprotkb:P48601 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111556|imex:IM-9552-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:F90B1C480F0F9030|rigid:18k+WDXOmNdmgfbv/IIi1oswUrI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9VJJ0 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111581|imex:IM-9552-388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:F62407227359B097|rigid:ckbv5IEu7l4tkPCSq7Zs+T4WI68 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VW54 uniprotkb:P48601 intact:EBI-164211|uniprotkb:Q9XZ26|ensemblmetazoa:FBpp0074662 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q9vw54_drome(display_long)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)|uniprotkb:"BcDNA:LD21723"(gene name synonym)|uniprotkb:Dmel\CG7762(gene name synonym)|uniprotkb:RPN1(gene name synonym)|uniprotkb:S2(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Dmel_CG7762(orf name)|uniprotkb:CG7762(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111571|imex:IM-9552-386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649158.1|flybase:FBgn0028695|interpro:IPR041433|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR040892|reactome:R-DME-382556|ensemblmetazoa:FBgn0028695(gene)|ensemblmetazoa:FBtr0074893(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:34XY3/zZaoyJH4owwclaQ98dE+s7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:FD7569EEC1A95862|rigid:wnlhbhL5FzVvn5uq8tUuuenqSBo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18413 uniprotkb:Q8IRD1 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111576|imex:IM-9552-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 intact-crc:7302F6871AB4F634|rigid:4e6tVryoab/u5bV9nIOde4FTRQU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VN44 uniprotkb:O97468 intact:EBI-112856|ensemblmetazoa:FBpp0078500|ensemblmetazoa:FBpp0307568 intact:EBI-2111069 psi-mi:q9vn44_drome(display_long)|uniprotkb:Karybeta3(gene name)|psi-mi:Karybeta3(display_short)|uniprotkb:Kary-beta-3(gene name synonym)|uniprotkb:Karybeta3-RA(gene name synonym)|uniprotkb:CG1059(orf name)|uniprotkb:Dmel\CG1059(gene name synonym)|uniprotkb:Karbeta3(gene name synonym)|uniprotkb:Kary-beta3(gene name synonym)|uniprotkb:"l(3)82CDd"(gene name synonym)|uniprotkb:"l(3)j3A4"(gene name synonym)|uniprotkb:"l(3)j7E8"(gene name synonym)|uniprotkb:Dmel_CG1059(orf name)|uniprotkb:karybeta3(gene name synonym) psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111611|imex:IM-9552-394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524226.1|flybase:FBgn0087013|refseq:NP_001262259.1|ensemblmetazoa:FBgn0087013(gene)|ensemblmetazoa:FBtr0078860(transcript)|ensemblmetazoa:FBtr0336462(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653 flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UKRoASiwq9rXvLHxdpr/vCE9yuo7227 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 intact-crc:508EB22394E186B3|rigid:LdA2Vw27zTQ8wIhqAz1HYVQ/V/s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8MSM3 uniprotkb:Q24474 intact:EBI-2111025 intact:EBI-2111020|uniprotkb:Q7KU26|ensemblmetazoa:FBpp0077323|ensemblmetazoa:FBpp0077325|ensemblmetazoa:FBpp0099898|ensemblmetazoa:FBpp0288676 psi-mi:q8msm3_drome(display_long)|uniprotkb:CG8219(orf name) psi-mi:q24474_drome(display_long)|uniprotkb:CG3151(orf name)|uniprotkb:RBP9(gene name synonym)|uniprotkb:Rbp9(gene name)|psi-mi:Rbp9(display_short)|uniprotkb:CG15402(gene name synonym)|uniprotkb:Dmel\CG3151(gene name synonym)|uniprotkb:RBP9-2(gene name synonym)|uniprotkb:RRM10(gene name synonym)|uniprotkb:RRM9(gene name synonym)|uniprotkb:Rbp10(gene name synonym)|uniprotkb:Rpb9(gene name synonym)|uniprotkb:fes(gene name synonym)|uniprotkb:"fs(2)B"(gene name synonym)|uniprotkb:rbp(gene name synonym)|uniprotkb:rbp9(gene name synonym)|uniprotkb:rbp9a(gene name synonym)|uniprotkb:rrm10(gene name synonym)|uniprotkb:rrm9(gene name synonym)|uniprotkb:Dmel_CG3151(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111606|imex:IM-9552-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0035693|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122 refseq:NP_001014462.1|refseq:NP_476936.3|refseq:NP_599125.1|refseq:NP_599126.1|flybase:FBgn0010263|ensemblmetazoa:FBgn0010263(gene)|ensemblmetazoa:FBtr0077638(transcript)|ensemblmetazoa:FBtr0077640(transcript)|ensemblmetazoa:FBtr0100468(transcript)|ensemblmetazoa:FBtr0290237(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0048477"(oogenesis)|go:"GO:0060856"(establishment of blood-brain barrier)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:chaW+EBN77dTZq+gUMAuDnJtXiI7227 rogid:W49ehf3/lWaZcoguI/G/lXxlXZw7227 intact-crc:0DEC5920F4EA5650|rigid:qXf5iNRha+LdRHJK5Bb32Z4ZYB8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:Q9VJJ0 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111586|imex:IM-9552-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:0194E0B522187BD0|rigid:ZmCyXy0SrBPC9gbauAcQQOyokBQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VW54 uniprotkb:Q9VTQ9 intact:EBI-164211|uniprotkb:Q9XZ26|ensemblmetazoa:FBpp0074662 intact:EBI-145364|ensemblmetazoa:FBpp0075772|ensemblmetazoa:FBpp0312163 psi-mi:q9vw54_drome(display_long)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)|uniprotkb:"BcDNA:LD21723"(gene name synonym)|uniprotkb:Dmel\CG7762(gene name synonym)|uniprotkb:RPN1(gene name synonym)|uniprotkb:S2(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Dmel_CG7762(orf name)|uniprotkb:CG7762(orf name) psi-mi:q9vtq9_drome(display_long)|uniprotkb:DmCG7257(gene name synonym)|uniprotkb:Dm_Rpt4c(gene name synonym)|uniprotkb:Dmel\CG7257(gene name synonym)|uniprotkb:Dmel_CG7257(orf name)|uniprotkb:7257(gene name synonym)|uniprotkb:Rpt4R(gene name)|psi-mi:Rpt4R(display_short)|uniprotkb:CG7257(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111596|imex:IM-9552-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649158.1|flybase:FBgn0028695|interpro:IPR041433|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR040892|reactome:R-DME-382556|ensemblmetazoa:FBgn0028695(gene)|ensemblmetazoa:FBtr0074893(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_648525.1|flybase:FBgn0036224|refseq:NP_001287039.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|ensemblmetazoa:FBtr0346545(transcript)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|ensemblmetazoa:FBgn0036224(gene)|ensemblmetazoa:FBtr0076040(transcript) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:34XY3/zZaoyJH4owwclaQ98dE+s7227 rogid:qKddY9ayACDKkIZPibAZTgXAvJE7227 intact-crc:873D93E13277DFF4|rigid:IL/7btVidr6A/HnVorW7A4552UQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T8V8 uniprotkb:P40301 intact:EBI-1630532 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111591|imex:IM-9552-390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:CA762896DDDFD993|rigid:cR2+8yTiEPIj6qEJvPuHRZd0iSo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VW54 uniprotkb:Q8IRD1 intact:EBI-164211|uniprotkb:Q9XZ26|ensemblmetazoa:FBpp0074662 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 psi-mi:q9vw54_drome(display_long)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)|uniprotkb:"BcDNA:LD21723"(gene name synonym)|uniprotkb:Dmel\CG7762(gene name synonym)|uniprotkb:RPN1(gene name synonym)|uniprotkb:S2(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Dmel_CG7762(orf name)|uniprotkb:CG7762(orf name) psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111601|imex:IM-9552-392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649158.1|flybase:FBgn0028695|interpro:IPR041433|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR040892|reactome:R-DME-382556|ensemblmetazoa:FBgn0028695(gene)|ensemblmetazoa:FBtr0074893(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:34XY3/zZaoyJH4owwclaQ98dE+s7227 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 intact-crc:34A058BC1BFFE101|rigid:2R/kLPfHF+c8fYsGNZL9X78/pZA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:Q9VNA5 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111636|imex:IM-9552-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 intact-crc:25A0954DC4C5C6ED|rigid:teDSifK2s+lAtxLzl4UM/WLLUxw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KN62-1 uniprotkb:P48601 intact:EBI-1895039|ensemblmetazoa:FBpp0087479 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q7kn62-1(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111631|imex:IM-9552-398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-224053(isoform-parent)|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:F08DB52EB9D3AF18|rigid:PvLu92plhxDfOoga0L69jAryCXc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:P12881 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111616|imex:IM-9552-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 intact-crc:C722D88DC004CCAB|rigid:TBOE9yR+VY9WthuQF3FxtdE9I8Q false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XYN7 uniprotkb:Q9VK14 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 intact:EBI-166677|ensemblmetazoa:FBpp0080028 psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111621|imex:IM-9552-396 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 intact-crc:D50EF2E906509540|rigid:XVvY8bLz3PpdHC/7/ARVd3ZosFc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9V5C6 uniprotkb:Q9XYN7 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111626|imex:IM-9552-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:7E7F92F612528DEA|rigid:SQgcBqCN+XrwbbsO3ROzZPg2oQ8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T8V8 uniprotkb:Q9XYN7 intact:EBI-1630532 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111656|imex:IM-9552-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:D4CAD7FB90F401A3|rigid:XcNVbSpQvP7P46opAo0tQNjSSpA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IRD1 uniprotkb:Q9VK14 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 intact:EBI-166677|ensemblmetazoa:FBpp0080028 psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:q9vk14_drome(display_long)|uniprotkb:Prosalpha6T(gene name)|psi-mi:Prosalpha6T(display_short)|uniprotkb:Pros-alpha-6T(gene name synonym)|uniprotkb:CG5648(orf name)|uniprotkb:5648(gene name synonym)|uniprotkb:Alpha6T(gene name synonym)|uniprotkb:Dmel\CG5648(gene name synonym)|uniprotkb:alpha6T(gene name synonym)|uniprotkb:prosalpha6T(gene name synonym)|uniprotkb:Dmel_CG5648(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111641|imex:IM-9552-400 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 refseq:NP_609623.1|flybase:FBgn0032492|ensemblmetazoa:FBgn0032492(gene)|ensemblmetazoa:FBtr0080448(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 rogid:VIHFyBnB98IrVcC8CNijF1C1nSU7227 intact-crc:4753D441C9301DBB|rigid:TNOG47AmivzfeJzMTlgj6pA99eU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KMP8 uniprotkb:P26270 intact:EBI-151692|intact:EBI-2109416|ensemblmetazoa:FBpp0083860|ensemblmetazoa:FBpp0083861 intact:EBI-253612|uniprotkb:Q9W178|ensemblmetazoa:FBpp0072197|ensemblmetazoa:FBpp0305141 psi-mi:q7kmp8_drome(display_long)|uniprotkb:Rpn9(gene name)|psi-mi:Rpn9(display_short)|uniprotkb:06(gene name synonym)|uniprotkb:0718(gene name synonym)|uniprotkb:718(gene name synonym)|uniprotkb:CT28749(gene name synonym)|uniprotkb:Dmel\CG10230(gene name synonym)|uniprotkb:PSMD13(gene name synonym)|uniprotkb:Rpn4(gene name synonym)|uniprotkb:Rpn94(gene name synonym)|uniprotkb:S11(gene name synonym)|uniprotkb:"l(3)S071806"(gene name synonym)|uniprotkb:"l(3)S071806b"(gene name synonym)|uniprotkb:p39A(gene name synonym)|uniprotkb:rpn9(gene name synonym)|uniprotkb:Dmel_CG10230(orf name)|uniprotkb:CG10230(orf name)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym) psi-mi:psmd7_drome(display_long)|uniprotkb:Rpn8(gene name)|psi-mi:Rpn8(display_short)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Mov34(gene name synonym)|uniprotkb:Proteasome subunit p39B(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Protein Mov34(gene name synonym)|uniprotkb:CG3416(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111646|imex:IM-9552-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651177.1|refseq:NP_732899.1|flybase:FBgn0028691|ensemblmetazoa:FBgn0028691(gene)|ensemblmetazoa:FBtr0084469(transcript)|ensemblmetazoa:FBtr0084470(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_523845.2|flybase:FBgn0002787|refseq:NP_001261168.1|dip:DIP-22847N|ensemblmetazoa:FBgn0002787(gene)|ensemblmetazoa:FBtr0072290(transcript)|ensemblmetazoa:FBtr0332921(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030425"(dendrite)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hEc3E83aGFg8Gw9MZx51ViGA3Qk7227 rogid:uumt4qHX3HyGRP7TmOChNpQhO+87227 intact-crc:267F3D03BA5E71A1|rigid:oIjWlrnLpTkdcqW+OlmW2+F73z0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:P48601 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111651|imex:IM-9552-402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:30923F1A914507EC|rigid:FyXvNCfbbaQiP14DbGM+QbMNIks false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KTP7 uniprotkb:Q9V5C6 intact:EBI-196108|intact:EBI-2111129|intact:EBI-498562|uniprotkb:Q494G2|ensemblmetazoa:FBpp0306241|ensemblmetazoa:FBpp0306242|ensemblmetazoa:FBpp0306243|ensemblmetazoa:FBpp0306244|ensemblmetazoa:FBpp0306245 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 psi-mi:q7ktp7_drome(display_long)|uniprotkb:CG5822(gene name)|psi-mi:CG5822(display_short)|uniprotkb:Dmel\CG44001(gene name synonym)|uniprotkb:CG31919(orf name)|uniprotkb:CG44001(orf name)|uniprotkb:Dmel_CG44001(orf name) psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111671|imex:IM-9552-406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264743|refseq:NP_001033874.2|refseq:NP_001162882.2|refseq:NP_608900.3|refseq:NP_723051.2|refseq:NP_723052.2|ensemblmetazoa:FBgn0264743(gene)|ensemblmetazoa:FBtr0334124(transcript)|ensemblmetazoa:FBtr0334125(transcript)|ensemblmetazoa:FBtr0334126(transcript)|ensemblmetazoa:FBtr0334127(transcript)|ensemblmetazoa:FBtr0334128(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Nmd2MIuypaUtOVbcArZIiNgUULo7227 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 intact-crc:20397DEAF9795A54|rigid:AdIZ6E8/3JHAuT263AIlLENwr8w false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:Q8IRD1 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111661|imex:IM-9552-404 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 intact-crc:3D97D4278104C724|rigid:lCl6ybNUFKvK7LePWStyvoft0gI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O18413 uniprotkb:Q9VJ33 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 intact:EBI-90023|uniprotkb:Q29QE5|ensemblmetazoa:FBpp0080733|ensemblmetazoa:FBpp0309711 psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:nedd8_drome(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:CG10679(orf name)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111666|imex:IM-9552-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_609919.1|flybase:FBgn0032725|ensemblmetazoa:FBgn0032725(gene)|ensemblmetazoa:FBtr0081192(transcript)|ensemblmetazoa:FBtr0342928(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030431"(sleep)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-DME-5689603|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-917937|refseq:NP_001286070.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 rogid:3P7TFMLheJ3IKTDNacGZdCxjrVc7227 intact-crc:6BA6F0FA54C70AA9|rigid:kUM0C6AMi2hX6Yc3ITo3M5L3dQ4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:P45890 intact:EBI-2110884 intact:EBI-163314|uniprotkb:Q9VXQ9|ensemblmetazoa:FBpp0073983 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:arp6_drome(display_long)|uniprotkb:Arp6(gene name)|psi-mi:Arp6(display_short)|uniprotkb:Acrp(gene name synonym)|uniprotkb:Actin-like protein 13E(gene name synonym)|uniprotkb:Actr13E(gene name synonym)|uniprotkb:Arp4(gene name synonym)|uniprotkb:CG11678(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111686|imex:IM-9552-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_511165.1|flybase:FBgn0011741|ensemblmetazoa:FBgn0011741(gene)|ensemblmetazoa:FBtr0074203(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR030054|interpro:IPR043129|dip:DIP-17460N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:fNEtOV1jHVnwUWXJuFmxJKcO76Y7227 intact-crc:9946671A30EA8718|rigid:tmSbbXOlVb5474BQhn//FCYodb8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K306 uniprotkb:Q8T0S6 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111676|imex:IM-9552-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 intact-crc:A1264DA7262F9C4B|rigid:QiqIOrDo4I0eQnu6hckAQlPR0Us false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VW54 uniprotkb:Q9VCD5 intact:EBI-164211|uniprotkb:Q9XZ26|ensemblmetazoa:FBpp0074662 intact:EBI-139147|ensemblmetazoa:FBpp0083927 psi-mi:q9vw54_drome(display_long)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)|uniprotkb:"BcDNA:LD21723"(gene name synonym)|uniprotkb:Dmel\CG7762(gene name synonym)|uniprotkb:RPN1(gene name synonym)|uniprotkb:S2(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Dmel_CG7762(orf name)|uniprotkb:CG7762(orf name) psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111681|imex:IM-9552-408 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649158.1|flybase:FBgn0028695|interpro:IPR041433|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR040892|reactome:R-DME-382556|ensemblmetazoa:FBgn0028695(gene)|ensemblmetazoa:FBtr0074893(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:34XY3/zZaoyJH4owwclaQ98dE+s7227 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 intact-crc:D8B27F4312A99590|rigid:hvxqz5RZgaVAcLJcnOcnpa87+yg false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWD9 uniprotkb:P15357 intact:EBI-100499|ensemblmetazoa:FBpp0074519|ensemblmetazoa:FBpp0309477 intact:EBI-414595|ensemblmetazoa:FBpp0079606|uniprotkb:Q9VKW6|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4 psi-mi:q9vwd9_drome(display_long)|uniprotkb:Ubqn(gene name)|psi-mi:Ubqn(display_short)|uniprotkb:CG14224(orf name)|uniprotkb:"BEST:LD26923"(gene name synonym)|uniprotkb:Chap(gene name synonym)|uniprotkb:DSK2(gene name synonym)|uniprotkb:Dmel\CG14224(gene name synonym)|uniprotkb:Dsk2(gene name synonym)|uniprotkb:UBQLN homolog(gene name synonym)|uniprotkb:UBQLN1(gene name synonym)|uniprotkb:anon-18DEa(gene name synonym)|uniprotkb:clone 5.42(gene name synonym)|uniprotkb:dUbqln(gene name synonym)|uniprotkb:dUbqn(gene name synonym)|uniprotkb:ubqn(gene name synonym)|uniprotkb:Dmel_CG14224(orf name)|uniprotkb:dsk2(gene name synonym) psi-mi:rs27a_drome(display_long)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UB3-D(gene name synonym)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG5271(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111706|imex:IM-9552-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608344.1|flybase:FBgn0031057|ensemblmetazoa:FBgn0031057(gene)|ensemblmetazoa:FBtr0074750(transcript)|ensemblmetazoa:FBtr0340612(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|reactome:R-DME-8856825|go:"GO:0005829"(cytosol)|refseq:NP_001285457.1 reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-216167|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5358346|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-538864|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-5607761|reactome:R-DME-6782210|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-5632684|reactome:R-DME-8866652|reactome:R-DME-5654726|reactome:R-DME-8866654|reactome:R-DME-5654727|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-5654732|reactome:R-DME-8941858|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-8948747|reactome:R-DME-5687128|reactome:R-DME-8948751|reactome:R-DME-5689603|reactome:R-DME-8951664|reactome:R-DME-5689877|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168|reactome:R-DME-912631|ensemblmetazoa:FBgn0003942(gene)|ensemblmetazoa:FBtr0080016(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|refseq:NP_476778.1|flybase:FBgn0003942 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:tyrm7R6Odh66OLSedxkxezyamS07227 rogid:/TxjkqKvf9HDOWxFySkJFjLFBLM7227 intact-crc:7CD21A4762E0645E|rigid:F+Q+50UmCwte7u+p5bjFiD39NTc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VNA5 uniprotkb:Q8T8V8 intact:EBI-98473|intact:EBI-1627772|uniprotkb:A4V2F4|ensemblmetazoa:FBpp0078448|ensemblmetazoa:FBpp0078449 intact:EBI-1630532 psi-mi:psb4_drome(display_long)|uniprotkb:CG12000(orf name)|uniprotkb:Prosbeta7(gene name)|psi-mi:Prosbeta7(display_short)|uniprotkb:Prosb4(gene name synonym)|uniprotkb:Prosbeta4(gene name synonym)|uniprotkb:Proteasome subunit beta type-7(gene name synonym) psi-mi:q8t8v8_drome(display_long)|uniprotkb:Prosbeta5R1(gene name)|psi-mi:Prosbeta5R1(display_short)|uniprotkb:Pros-beta-5R1(gene name synonym)|uniprotkb:Prosbeta5R(gene name synonym)|uniprotkb:CG9868(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111691|imex:IM-9552-410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649529.1|refseq:NP_730922.1|flybase:FBgn0250746|ensemblmetazoa:FBgn0250746(gene)|ensemblmetazoa:FBtr0078805(transcript)|ensemblmetazoa:FBtr0078806(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-187577|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-19164N go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|flybase:FBgn0034842 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:hBkx4mH02N2n5GOgNvzr/kkrqaI7227 rogid:p/r0NEBvG9EdBbJ0SH3yHfQzV047227 intact-crc:F023C34D041C7B69|rigid:mIm7tQqvvCO4Pw3DfBM6obsUfRM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P91632 uniprotkb:Q7JN15 intact:EBI-107282|ensemblmetazoa:FBpp0078122 intact:EBI-2111140|ensemblmetazoa:FBpp0084256 psi-mi:p91632_drome(display_long)|uniprotkb:mub(gene name)|psi-mi:mub(display_short)|uniprotkb:CG7437(orf name)|uniprotkb:Dmel\CG7437(gene name synonym)|uniprotkb:MRE17(gene name synonym)|uniprotkb:MUB(gene name synonym)|uniprotkb:Mub(gene name synonym)|uniprotkb:anon-WO0172774.33(gene name synonym)|uniprotkb:anon-WO0172774.35(gene name synonym)|uniprotkb:anon-WO0172774.36(gene name synonym)|uniprotkb:anon-WO0172774.37(gene name synonym)|uniprotkb:"l(3)04093"(gene name synonym)|uniprotkb:"l(3)j6B10"(gene name synonym)|uniprotkb:"l(3)j8B3"(gene name synonym)|uniprotkb:Dmel_CG7437(orf name) psi-mi:q7jn15_drome(display_long)|uniprotkb:msi(gene name)|psi-mi:msi(display_short)|uniprotkb:CG5099(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111696|imex:IM-9552-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524208.1|flybase:FBgn0262737|ensemblmetazoa:FBgn0262737(gene)|ensemblmetazoa:FBtr0078468(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 flybase:FBgn0011666|ensemblmetazoa:FBgn0011666(gene)|ensemblmetazoa:FBtr0084882(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0001709"(cell fate determination)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022416"(chaeta development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:R2NzFqof/qLNIUm7C01xHwVakQk7227 rogid:nl81bRYxT/uQS/uagdpSq92reJg7227 intact-crc:9D9D2FD7D70D7114|rigid:293Px9HW3JqIX3XADf/eTmSsE9w false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VKW3 uniprotkb:P17917 intact:EBI-118156|uniprotkb:Q9NGN8|ensemblmetazoa:FBpp0079609 intact:EBI-148806|intact:EBI-1628820|uniprotkb:Q9V909|uniprotkb:Q540V1|ensemblmetazoa:FBpp0085619|ensemblmetazoa:FBpp0089395 psi-mi:q9vkw3_drome(display_long)|uniprotkb:RfC3(gene name)|psi-mi:RfC3(display_short)|uniprotkb:CG5313(orf name)|uniprotkb:DRFC(gene name synonym)|uniprotkb:DmRFC3(gene name synonym)|uniprotkb:Dmel\CG5313(gene name synonym)|uniprotkb:Rfc3(gene name synonym)|uniprotkb:Dmel_CG5313(orf name) psi-mi:pcna_drome(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)|uniprotkb:Mutagen-sensitive 209 protein(gene name synonym)|uniprotkb:mus209(gene name synonym)|uniprotkb:CG9193(orf name)|uniprotkb:PCNA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111701|imex:IM-9552-412 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609399.1|flybase:FBgn0032244|ensemblmetazoa:FBgn0032244(gene)|ensemblmetazoa:FBtr0080019(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-174411|reactome:R-DME-176187|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696397|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-69091 refseq:NP_476905.1|refseq:NP_995904.1|flybase:FBgn0005655|dip:DIP-20560N|reactome:R-DME-5358565|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6804114|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183|reactome:R-DME-110320|ensemblmetazoa:FBgn0005655(gene)|ensemblmetazoa:FBtr0086307(transcript)|ensemblmetazoa:FBtr0086308(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0009411"(response to UV)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043626"(PCNA complex)|go:"GO:0072702"(response to methyl methanesulfonate)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:4HK1|reactome:R-DME-110312|reactome:R-DME-110314 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:NVFRniFabAzSoVPVU0MgLhkoYCo7227 rogid:JlorjL2CuAoJHo8z4Cnb16+Muf87227 intact-crc:1F81F08BE1EE7F85|rigid:ovax0WeK0o6wOPBeVFpj6C2cCBI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9XYN7 uniprotkb:O18413 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 intact:EBI-174806|uniprotkb:O45023|ensemblmetazoa:FBpp0076890 psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:prs8_drome(display_long)|uniprotkb:Rpt6(gene name)|psi-mi:Rpt6(display_short)|uniprotkb:DUG(gene name synonym)|uniprotkb:Pros45(gene name synonym)|uniprotkb:Ug(gene name synonym)|uniprotkb:CG1489(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111731|imex:IM-9552-418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N refseq:NP_608447.1|flybase:FBgn0020369|dip:DIP-20087N|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|ensemblmetazoa:FBgn0020369(gene)|ensemblmetazoa:FBtr0077189(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 rogid:Qh2nalx93YInrcewzARIx1xhS1M7227 intact-crc:B86C44CC9ADC4670|rigid:JxuJhd7kW/dHonfc7xxJDRK31/o false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:Q9VJJ0 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111726|imex:IM-9552-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:D683ECFD8DDE0DDA|rigid:MpQYTvX0e5nCMzuGwYfZP4AeUyM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VWD9 uniprotkb:P68198 intact:EBI-100499|ensemblmetazoa:FBpp0074519|ensemblmetazoa:FBpp0309477 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N psi-mi:q9vwd9_drome(display_long)|uniprotkb:Ubqn(gene name)|psi-mi:Ubqn(display_short)|uniprotkb:CG14224(orf name)|uniprotkb:"BEST:LD26923"(gene name synonym)|uniprotkb:Chap(gene name synonym)|uniprotkb:DSK2(gene name synonym)|uniprotkb:Dmel\CG14224(gene name synonym)|uniprotkb:Dsk2(gene name synonym)|uniprotkb:UBQLN homolog(gene name synonym)|uniprotkb:UBQLN1(gene name synonym)|uniprotkb:anon-18DEa(gene name synonym)|uniprotkb:clone 5.42(gene name synonym)|uniprotkb:dUbqln(gene name synonym)|uniprotkb:dUbqn(gene name synonym)|uniprotkb:ubqn(gene name synonym)|uniprotkb:Dmel_CG14224(orf name)|uniprotkb:dsk2(gene name synonym) psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111711|imex:IM-9552-414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608344.1|flybase:FBgn0031057|ensemblmetazoa:FBgn0031057(gene)|ensemblmetazoa:FBtr0074750(transcript)|ensemblmetazoa:FBtr0340612(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|reactome:R-DME-8856825|go:"GO:0005829"(cytosol)|refseq:NP_001285457.1 interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:tyrm7R6Odh66OLSedxkxezyamS07227 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 intact-crc:E3A20DAD1318A506|rigid:4hiU/Al+JsAEMPeIcDTWWrM6KyQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VJ33 uniprotkb:Q9VCD5 intact:EBI-90023|uniprotkb:Q29QE5|ensemblmetazoa:FBpp0080733|ensemblmetazoa:FBpp0309711 intact:EBI-139147|ensemblmetazoa:FBpp0083927 psi-mi:nedd8_drome(display_long)|uniprotkb:Nedd8(gene name)|psi-mi:Nedd8(display_short)|uniprotkb:CG10679(orf name)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym) psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111716|imex:IM-9552-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609919.1|flybase:FBgn0032725|ensemblmetazoa:FBgn0032725(gene)|ensemblmetazoa:FBtr0081192(transcript)|ensemblmetazoa:FBtr0342928(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030431"(sleep)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|reactome:R-DME-5689603|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-917937|refseq:NP_001286070.1 refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:3P7TFMLheJ3IKTDNacGZdCxjrVc7227 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 intact-crc:C4680C98927CA15F|rigid:dPNobasWKw87hr4h6S33Z8Aa0E4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P12881 uniprotkb:Q9XYN7 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-119764|uniprotkb:A0APH4|ensemblmetazoa:FBpp0081488 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:psb3_drome(display_long)|uniprotkb:Prosbeta3(gene name)|psi-mi:Prosbeta3(display_short)|uniprotkb:20S proteasome subunit beta-3(gene name synonym)|uniprotkb:CG11981(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111721|imex:IM-9552-416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_649858.1|flybase:FBgn0026380|ensemblmetazoa:FBgn0026380(gene)|ensemblmetazoa:FBtr0082010(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-382556|reactome:R-DME-5689603|reactome:R-DME-5689880|interpro:IPR029055|interpro:IPR033811|go:"GO:0004298"(threonine-type endopeptidase activity)|reactome:R-DME-1169091|reactome:R-DME-1234176|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1236978|reactome:R-DME-174084|go:"GO:0005829"(cytosol)|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-18901N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:fxVynlBbal7SodDbHs5AO74gJVE7227 intact-crc:F6F9666C016C7760|rigid:c4ZkOvy+k84WMauSOtyFhKqP/kA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:Q9VWD9 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-100499|ensemblmetazoa:FBpp0074519|ensemblmetazoa:FBpp0309477 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:q9vwd9_drome(display_long)|uniprotkb:Ubqn(gene name)|psi-mi:Ubqn(display_short)|uniprotkb:CG14224(orf name)|uniprotkb:"BEST:LD26923"(gene name synonym)|uniprotkb:Chap(gene name synonym)|uniprotkb:DSK2(gene name synonym)|uniprotkb:Dmel\CG14224(gene name synonym)|uniprotkb:Dsk2(gene name synonym)|uniprotkb:UBQLN homolog(gene name synonym)|uniprotkb:UBQLN1(gene name synonym)|uniprotkb:anon-18DEa(gene name synonym)|uniprotkb:clone 5.42(gene name synonym)|uniprotkb:dUbqln(gene name synonym)|uniprotkb:dUbqn(gene name synonym)|uniprotkb:ubqn(gene name synonym)|uniprotkb:Dmel_CG14224(orf name)|uniprotkb:dsk2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111755|imex:IM-9552-422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 refseq:NP_608344.1|flybase:FBgn0031057|ensemblmetazoa:FBgn0031057(gene)|ensemblmetazoa:FBtr0074750(transcript)|ensemblmetazoa:FBtr0340612(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|reactome:R-DME-8856825|go:"GO:0005829"(cytosol)|refseq:NP_001285457.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:tyrm7R6Odh66OLSedxkxezyamS07227 intact-crc:F436553CB604771F|rigid:xZlmngm6MWF6s8E6qOUWQhytDc0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:P92208 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111736|imex:IM-9552-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 intact-crc:1AA43E4A48599307|rigid:idc2f69oaj5b2ANJ6/lNgS49NA0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P15357 uniprotkb:P18101 intact:EBI-414595|ensemblmetazoa:FBpp0079606|uniprotkb:Q9VKW6|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4 intact:EBI-2111744|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VZL4|uniprotkb:Q9VQX7|ensemblmetazoa:FBpp0077159|ensemblmetazoa:FBpp0306837 psi-mi:rs27a_drome(display_long)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UB3-D(gene name synonym)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG5271(orf name) psi-mi:rl40_drome(display_long)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:UBI-F52(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:CG2960(orf name)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111741|imex:IM-9552-420 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-216167|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5358346|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-538864|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-5607761|reactome:R-DME-6782210|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-5632684|reactome:R-DME-8866652|reactome:R-DME-5654726|reactome:R-DME-8866654|reactome:R-DME-5654727|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-5654732|reactome:R-DME-8941858|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-8948747|reactome:R-DME-5687128|reactome:R-DME-8948751|reactome:R-DME-5689603|reactome:R-DME-8951664|reactome:R-DME-5689877|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168|reactome:R-DME-912631|ensemblmetazoa:FBgn0003942(gene)|ensemblmetazoa:FBtr0080016(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|refseq:NP_476778.1|flybase:FBgn0003942 refseq:NP_476776.1|flybase:FBgn0003941|refseq:NP_001260018.1|ensemblmetazoa:FBgn0003941(gene)|ensemblmetazoa:FBtr0077470(transcript)|ensemblmetazoa:FBtr0334787(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689877|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72689|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948747|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-912631|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/TxjkqKvf9HDOWxFySkJFjLFBLM7227 rogid:9vNVDJ3SvdO2vhXnOZV9lxLhgts7227 intact-crc:D6C7BE92A00DA9FC|rigid:9s+H4XY2r4x9jA19B2IW5KfkELU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VCD5 uniprotkb:Q8T6B9 intact:EBI-139147|ensemblmetazoa:FBpp0083927 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 psi-mi:q9vcd5_drome(display_long)|uniprotkb:Dmel\CG10694(gene name)|psi-mi:Dmel\CG10694(display_short)|uniprotkb:CG10694(orf name)|uniprotkb:Dmel_CG10694(orf name) psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111750|imex:IM-9552-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651212.1|flybase:FBgn0039147|ensemblmetazoa:FBgn0039147(gene)|ensemblmetazoa:FBtr0084542(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|reactome:R-DME-532668|reactome:R-DME-5696394|reactome:R-DME-5696395 refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:GvhSuMcOaEzGPXPnXEuXx4UYXs47227 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 intact-crc:495CFA68EC840945|rigid:+S7cqMeC5uaVlIL8gD0nnchRdDc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7KLW6 uniprotkb:P17917 intact:EBI-2111778|ensemblmetazoa:FBpp0311114 intact:EBI-148806|intact:EBI-1628820|uniprotkb:Q9V909|uniprotkb:Q540V1|ensemblmetazoa:FBpp0085619|ensemblmetazoa:FBpp0089395 psi-mi:q7klw6_drome(display_long)|uniprotkb:"BcDNA:LD06837"(gene name synonym)|uniprotkb:RfC38(gene name)|psi-mi:RfC38(display_short)|uniprotkb:CG6258(orf name) psi-mi:pcna_drome(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)|uniprotkb:Mutagen-sensitive 209 protein(gene name synonym)|uniprotkb:mus209(gene name synonym)|uniprotkb:CG9193(orf name)|uniprotkb:PCNA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111775|imex:IM-9552-426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028700|ensemblmetazoa:FBgn0028700(gene)|ensemblmetazoa:FBtr0344786(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417 refseq:NP_476905.1|refseq:NP_995904.1|flybase:FBgn0005655|dip:DIP-20560N|reactome:R-DME-5358565|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6804114|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183|reactome:R-DME-110320|ensemblmetazoa:FBgn0005655(gene)|ensemblmetazoa:FBtr0086307(transcript)|ensemblmetazoa:FBtr0086308(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0009411"(response to UV)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043626"(PCNA complex)|go:"GO:0072702"(response to methyl methanesulfonate)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:4HK1|reactome:R-DME-110312|reactome:R-DME-110314 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:4IUo374TVbT8s4PaHv5MSjBDbOc7227 rogid:JlorjL2CuAoJHo8z4Cnb16+Muf87227 intact-crc:9FAA9AC84352F742|rigid:XDQyvBqkqAEz9aYEsYl58q6U0cU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VM49 uniprotkb:O97468 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 intact:EBI-2111069 psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:o97468_drome(display_long)|uniprotkb:CG10327(orf name)|uniprotkb:TBPH(gene name)|psi-mi:TBPH(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111760|imex:IM-9552-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 flybase:FBgn0025790|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008380"(RNA splicing)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031673"(H zone)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0033143"(regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0040011"(locomotion)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072553"(terminal button organization)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1990605"(GU repeat RNA binding)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 rogid:jwDgJHlfwtjtErBUdwzkPBD82W87227 intact-crc:8A61001B9EB10148|rigid:H3BK4Gdzoj8LMapbmy3+guSgkGM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q7K306 uniprotkb:Q9VZF4 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 intact:EBI-138334|intact:EBI-1628008|uniprotkb:A4V1G6|ensemblmetazoa:FBpp0073101|ensemblmetazoa:FBpp0073102|ensemblmetazoa:FBpp0073103 psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:fbxw7_drome(display_long)|uniprotkb:ago(gene name)|psi-mi:ago(display_short)|uniprotkb:CG15010(orf name)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)|uniprotkb:Protein archipelago(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111765|imex:IM-9552-424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|ensemblmetazoa:FBtr0073246(transcript)|ensemblmetazoa:FBtr0073247(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007419"(ventral cord development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030332"(cyclin binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060438"(trachea development)|go:"GO:0071456"(cellular response to hypoxia)|ensemblmetazoa:FBgn0041171(gene)|ensemblmetazoa:FBtr0073245(transcript)|refseq:NP_523922.1|refseq:NP_728964.1|refseq:NP_728965.1|flybase:FBgn0041171|dip:DIP-32477N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 rogid:FVPUJUP1NZ/drDu6C4uA3VDNv307227 intact-crc:32B7DA9343558781|rigid:BevtFBXIoa+8xK9VXexb+W8WdjI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VW54 uniprotkb:Q9VJJ0 intact:EBI-164211|uniprotkb:Q9XZ26|ensemblmetazoa:FBpp0074662 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:q9vw54_drome(display_long)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)|uniprotkb:"BcDNA:LD21723"(gene name synonym)|uniprotkb:Dmel\CG7762(gene name synonym)|uniprotkb:RPN1(gene name synonym)|uniprotkb:S2(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Dmel_CG7762(orf name)|uniprotkb:CG7762(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111770|imex:IM-9552-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649158.1|flybase:FBgn0028695|interpro:IPR041433|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR040892|reactome:R-DME-382556|ensemblmetazoa:FBgn0028695(gene)|ensemblmetazoa:FBtr0074893(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:34XY3/zZaoyJH4owwclaQ98dE+s7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:414C446517284C4E|rigid:j5aYoa7bxdgZrFxCvrkU+ZmFuHM false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8T6B9-1 uniprotkb:P22769 intact:EBI-1446762|ensemblmetazoa:FBpp0072593 intact:EBI-93148|uniprotkb:Q9VXI9|ensemblmetazoa:FBpp0073989 psi-mi:q8t6b9-1(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name)|uniprotkb:Long(isoform synonym) psi-mi:psa71_drome(display_long)|uniprotkb:Prosalpha4(gene name)|psi-mi:Prosalpha4(display_short)|uniprotkb:PROS-28.1(gene name synonym)|uniprotkb:PROS-Dm28.1(gene name synonym)|uniprotkb:Pros28.1(gene name synonym)|uniprotkb:Proteasome 28 kDa subunit 1(gene name synonym)|uniprotkb:CG3422(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111784|imex:IM-9552-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-189756(isoform-parent)|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript) refseq:NP_525092.1|flybase:FBgn0004066|ensemblmetazoa:FBgn0004066(gene)|ensemblmetazoa:FBtr0074210(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-69601|reactome:R-DME-69017|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-450408|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-4608870|reactome:R-DME-432395|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|dip:DIP-17376N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 rogid:gQpRF01CDAsvV4Rc2YSFf8drjtY7227 intact-crc:E8E16AD13F3D4182|rigid:dRq3OZaMGPPCgkh2VVFgLB1t0I0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:O77135 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-185987|ensemblmetazoa:FBpp0082392 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:o77135_drome(display_long)|uniprotkb:spn-B(gene name)|psi-mi:spn-B(display_short)|uniprotkb:Dmel\CG3325(gene name synonym)|uniprotkb:Rad51(gene name synonym)|uniprotkb:Rad51-like(gene name synonym)|uniprotkb:Spn-B(gene name synonym)|uniprotkb:SpnB(gene name synonym)|uniprotkb:XRCC3(gene name synonym)|uniprotkb:rad51-like(gene name synonym)|uniprotkb:spnB(gene name synonym)|uniprotkb:Dmel_CG3325(orf name)|uniprotkb:CG3325(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111799|imex:IM-9552-430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 refseq:NP_476740.1|flybase:FBgn0003480|ensemblmetazoa:FBgn0003480(gene)|ensemblmetazoa:FBtr0082933(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005657"(replication fork)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006417"(regulation of translation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0009951"(polarity specification of dorsal/ventral axis)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048477"(oogenesis)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090656"(t-circle formation)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:9BiJ5Rk2VQEU9huh0WCAKh+rW0I7227 intact-crc:6B01A9550748D6E2|rigid:EXDc2pFg4wYs+Y46cmNWxv36N6o false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:Q9VRS0 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-146748|ensemblmetazoa:FBpp0076777 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:q9vrs0_drome(display_long)|uniprotkb:Dmel\CG10478(gene name synonym)|uniprotkb:g7295403(gene name synonym)|uniprotkb:alphaKap4(gene name)|psi-mi:alphaKap4(display_short)|uniprotkb:aKap4(gene name synonym)|uniprotkb:CG11040(gene name synonym)|uniprotkb:CG10478(orf name)|uniprotkb:Dmel_CG10478(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111789|imex:IM-9552-428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N refseq:NP_648007.1|flybase:FBgn0035657|ensemblmetazoa:FBgn0035657(gene)|ensemblmetazoa:FBtr0077069(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|interpro:IPR024931 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:HenyM5gRG32k8a1xGQM26ru2Y/g7227 intact-crc:F602E5C9267535E0|rigid:333K9eMb8vdEq61HxpJgNRPJ4H8 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VUR4 uniprotkb:O76460 intact:EBI-2108311|uniprotkb:D0IQC8|uniprotkb:Q8IQM4|ensemblmetazoa:FBpp0289558|ensemblmetazoa:FBpp0290404 intact:EBI-184970|uniprotkb:B6UXG7|uniprotkb:B6UXH8|uniprotkb:B6UXJ2|uniprotkb:B6UXJ5|uniprotkb:P91636|uniprotkb:Q7K0T1|uniprotkb:Q7KPH9|ensemblmetazoa:FBpp0077357 psi-mi:q9vur4_drome(display_long)|uniprotkb:Dmel\CG7656(gene name)|psi-mi:Dmel\CG7656(display_short)|uniprotkb:CG7656-RA(gene name synonym)|uniprotkb:CG7656(orf name)|uniprotkb:Dmel_CG7656(orf name) psi-mi:rad54_drome(display_long)|uniprotkb:okr(gene name)|psi-mi:okr(display_short)|uniprotkb:CG3736(orf name)|uniprotkb:RAD54(gene name synonym)|uniprotkb:RAD54 DNA repair protein(gene name synonym)|uniprotkb:Protein okra(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111794|imex:IM-9552-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648783.4|refseq:NP_730058.2|flybase:FBgn0036516|ensemblmetazoa:FBgn0036516(gene)|ensemblmetazoa:FBtr0300329(transcript)|ensemblmetazoa:FBtr0301186(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-8866652|reactome:R-DME-983168 refseq:NP_476661.1|flybase:FBgn0002989|ensemblmetazoa:FBgn0002989(gene)|ensemblmetazoa:FBtr0077673(transcript)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006417"(regulation of translation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016817"(hydrolase activity, acting on acid anhydrides)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0043150"(DNA synthesis involved in double-strand break repair via homologous recombination)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR013967(Rad54, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:coGA0MXK+GugXCL/79B7bYwsKwM7227 rogid:kHr3FgvM4M3Ge0IcIusTOO7QSl87227 intact-crc:AA09C6DA453ED2D3|rigid:nbl6PyuWG5iiVRZjB2j649BmwTw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P15357 uniprotkb:Q9VXF9 intact:EBI-414595|ensemblmetazoa:FBpp0079606|uniprotkb:Q9VKW6|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4 intact:EBI-125380|ensemblmetazoa:FBpp0074054|ensemblmetazoa:FBpp0310006 psi-mi:rs27a_drome(display_long)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UB3-D(gene name synonym)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG5271(orf name) psi-mi:q9vxf9_drome(display_long)|uniprotkb:rngo(gene name)|psi-mi:rngo(display_short)|uniprotkb:Dmel\CG4420(gene name synonym)|uniprotkb:Ddi1(gene name synonym)|uniprotkb:Rngo(gene name synonym)|uniprotkb:CG4420(orf name)|uniprotkb:Dmel_CG4420(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111823|imex:IM-9552-434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-216167|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5358346|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-538864|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-5607761|reactome:R-DME-6782210|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-5632684|reactome:R-DME-8866652|reactome:R-DME-5654726|reactome:R-DME-8866654|reactome:R-DME-5654727|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-5654732|reactome:R-DME-8941858|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-8948747|reactome:R-DME-5687128|reactome:R-DME-8948751|reactome:R-DME-5689603|reactome:R-DME-8951664|reactome:R-DME-5689877|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168|reactome:R-DME-912631|ensemblmetazoa:FBgn0003942(gene)|ensemblmetazoa:FBtr0080016(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|refseq:NP_476778.1|flybase:FBgn0003942 refseq:NP_573129.1|flybase:FBgn0030753|refseq:NP_001285328.1|ensemblmetazoa:FBgn0030753(gene)|ensemblmetazoa:FBtr0074278(transcript)|ensemblmetazoa:FBtr0343349(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/TxjkqKvf9HDOWxFySkJFjLFBLM7227 rogid:hCs9HfO9tfMlBe1ZQGzm44CNfCk7227 intact-crc:3E0EDBCD7A274BC9|rigid:OnOSFVnauqCeBXUaHYovguB4/cU false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P45890 uniprotkb:Q9VJJ0 intact:EBI-163314|uniprotkb:Q9VXQ9|ensemblmetazoa:FBpp0073983 intact:EBI-90888|ensemblmetazoa:FBpp0080490|ensemblmetazoa:FBpp0307141 psi-mi:arp6_drome(display_long)|uniprotkb:Arp6(gene name)|psi-mi:Arp6(display_short)|uniprotkb:Acrp(gene name synonym)|uniprotkb:Actin-like protein 13E(gene name synonym)|uniprotkb:Actr13E(gene name synonym)|uniprotkb:Arp4(gene name synonym)|uniprotkb:CG11678(orf name) psi-mi:q9vjj0_drome(display_long)|uniprotkb:Prosbeta4(gene name)|psi-mi:Prosbeta4(display_short)|uniprotkb:17331(gene name synonym)|uniprotkb:Beta-4(gene name synonym)|uniprotkb:Dmel\CG17331(gene name synonym)|uniprotkb:GC17331(gene name synonym)|uniprotkb:PSMB2(gene name synonym)|uniprotkb:Psmb2(gene name synonym)|uniprotkb:beta-4(gene name synonym)|uniprotkb:beta4(gene name synonym)|uniprotkb:Dmel_CG17331(orf name)|uniprotkb:CG17331(orf name)|uniprotkb:Pros beta4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111804|imex:IM-9552-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511165.1|flybase:FBgn0011741|ensemblmetazoa:FBgn0011741(gene)|ensemblmetazoa:FBtr0074203(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR030054|interpro:IPR043129|dip:DIP-17460N refseq:NP_609804.1|flybase:FBgn0032596|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|ensemblmetazoa:FBgn0032596(gene)|ensemblmetazoa:FBtr0080936(transcript)|ensemblmetazoa:FBtr0335142(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|reactome:R-DME-1169091|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|reactome:R-DME-1234176|go:"GO:0032504"(multicellular organism reproduction)|reactome:R-DME-1236978|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-983168|refseq:NP_001260511.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fNEtOV1jHVnwUWXJuFmxJKcO76Y7227 rogid:M91zGFHnX+ZSHdwNq7e1+FpzZsU7227 intact-crc:4B0D87238B2EE7B0|rigid:bkoh7tF9Dlc9GrEq8g67DvQiqbo false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P45890 uniprotkb:P48601 intact:EBI-163314|uniprotkb:Q9VXQ9|ensemblmetazoa:FBpp0073983 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:arp6_drome(display_long)|uniprotkb:Arp6(gene name)|psi-mi:Arp6(display_short)|uniprotkb:Acrp(gene name synonym)|uniprotkb:Actin-like protein 13E(gene name synonym)|uniprotkb:Actr13E(gene name synonym)|uniprotkb:Arp4(gene name synonym)|uniprotkb:CG11678(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111809|imex:IM-9552-432 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511165.1|flybase:FBgn0011741|ensemblmetazoa:FBgn0011741(gene)|ensemblmetazoa:FBtr0074203(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR030054|interpro:IPR043129|dip:DIP-17460N refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:fNEtOV1jHVnwUWXJuFmxJKcO76Y7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:D4767A48BE5C5283|rigid:GkGnwSN0pi4gh4v6qVMfVOrluvw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VYI0 uniprotkb:Q24534 intact:EBI-126770|uniprotkb:Q9NGV0|ensemblmetazoa:FBpp0073543|ensemblmetazoa:FBpp0112400|ensemblmetazoa:FBpp0297664|ensemblmetazoa:FBpp0300900|ensemblmetazoa:FBpp0305511|ensemblmetazoa:FBpp0305512 intact:EBI-2111817 psi-mi:q9vyi0_drome(display_long)|uniprotkb:fne(gene name)|psi-mi:fne(display_short)|uniprotkb:fne-RB(gene name synonym)|uniprotkb:"BEST:HL02010"(gene name synonym)|uniprotkb:"BcDNA:HL02010"(gene name synonym)|uniprotkb:"BcDNA:RE25290"(gene name synonym)|uniprotkb:CR32646(gene name synonym)|uniprotkb:Dmel\CG4396(gene name synonym)|uniprotkb:FNE(gene name synonym)|uniprotkb:Fne(gene name synonym)|uniprotkb:MRE28(gene name synonym)|uniprotkb:lincRNA.985(gene name synonym)|uniprotkb:Dmel_CG4396(orf name)|uniprotkb:CG4396(orf name)|uniprotkb:cg4396(gene name synonym) psi-mi:q24534_drome(display_long)|uniprotkb:SPX(gene name synonym)|uniprotkb:CG3780(orf name)|uniprotkb:Spx(gene name)|psi-mi:Spx(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111814|imex:IM-9552-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0086675(gene)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979|reactome:R-DME-450520|reactome:R-DME-72163|ensemblmetazoa:FBtr0073712(transcript)|ensemblmetazoa:FBtr0113493(transcript)|ensemblmetazoa:FBtr0306738(transcript)|ensemblmetazoa:FBtr0308694(transcript)|ensemblmetazoa:FBtr0333319(transcript)|ensemblmetazoa:FBtr0333320(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008049"(male courtship behavior)|refseq:NP_001096965.1|refseq:NP_572842.1|flybase:FBgn0086675|refseq:NP_001245646.1|refseq:NP_001245648.1|refseq:NP_001259497.1|refseq:NP_001259498.1 flybase:FBgn0015818|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|interpro:IPR034159|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:IxfHiln53BTh0NS5caA9LjvUpWc7227 rogid:Yio+QzxeOCvHgH9uPn63d7K49n47227 intact-crc:B9FC86F47C3E5E6B|rigid:SNPo6J55+eEXX1wDBlqc7ePXLL4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P49071 uniprotkb:Q7K306 intact:EBI-118687|uniprotkb:Q9W480|ensemblmetazoa:FBpp0070802|ensemblmetazoa:FBpp0070804|ensemblmetazoa:FBpp0292066|ensemblmetazoa:FBpp0300801 intact:EBI-160257|intact:EBI-2110914|ensemblmetazoa:FBpp0086249|ensemblmetazoa:FBpp0086250|ensemblmetazoa:FBpp0086251|ensemblmetazoa:FBpp0309069|ensemblmetazoa:FBpp0311495 psi-mi:mapk2_drome(display_long)|uniprotkb:MAPk-Ak2(gene name)|psi-mi:MAPk-Ak2(display_short)|uniprotkb:CG3086(orf name) psi-mi:q7k306_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:6(gene name synonym)|uniprotkb:8-6(gene name synonym)|uniprotkb:CDK4(gene name synonym)|uniprotkb:DmCdk4(gene name synonym)|uniprotkb:Dmel\CG5072(gene name synonym)|uniprotkb:Pk53C(gene name synonym)|uniprotkb:Pk?7(gene name synonym)|uniprotkb:cdk(gene name synonym)|uniprotkb:cdk4(gene name synonym)|uniprotkb:dCdk4(gene name synonym)|uniprotkb:"l(2)05428"(gene name synonym)|uniprotkb:"l(2)0671"(gene name synonym)|uniprotkb:"l(2)k06503"(gene name synonym)|uniprotkb:"l(2)s4639"(gene name synonym)|uniprotkb:"l(2)sh0671"(gene name synonym)|uniprotkb:CG5072(orf name)|uniprotkb:Dmel_CG5072(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111843|imex:IM-9552-438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001188547.1|refseq:NP_524769.1|refseq:NP_788861.1|flybase:FBgn0013987|ensemblmetazoa:FBgn0013987(gene)|ensemblmetazoa:FBtr0070837(transcript)|ensemblmetazoa:FBtr0070839(transcript)|ensemblmetazoa:FBtr0302940(transcript)|ensemblmetazoa:FBtr0308577(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009651"(response to salt stress)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0051019"(mitogen-activated protein kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|reactome:R-DME-171007|reactome:R-DME-199920|reactome:R-DME-2559580|reactome:R-DME-3371453|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450385|reactome:R-DME-450513|refseq:NP_001245536.1|dip:DIP-21714N refseq:NP_725595.1|flybase:FBgn0016131|refseq:NP_477196.1|refseq:NP_725594.1|ensemblmetazoa:FBtr0087103(transcript)|ensemblmetazoa:FBtr0087104(transcript)|ensemblmetazoa:FBtr0340063(transcript)|ensemblmetazoa:FBtr0345340(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|ensemblmetazoa:FBtr0087102(transcript)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-3214858|reactome:R-DME-69231|reactome:R-DME-75815|reactome:R-DME-8878166|reactome:R-DME-8934593|reactome:R-DME-9616222|go:"GO:0030332"(cyclin binding)|ensemblmetazoa:FBgn0016131(gene)|refseq:NP_001286493.1|refseq:NP_001286494.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:jOgW9S5IhMsBz2vBME8MBe9CyQI7227 rogid:TU1klGmuVHKdD/46NQg7hqA8rI47227 intact-crc:EC1E64D173656FED|rigid:Rzjqt7Xl9N9rSyjuidVgl94VPkA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O77430 uniprotkb:Q8T8S1 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-89202|uniprotkb:Q9V6I4|ensemblmetazoa:FBpp0086916|ensemblmetazoa:FBpp0086917|ensemblmetazoa:FBpp0086918 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q8t8s1_drome(display_long)|uniprotkb:SCCRO3(gene name)|psi-mi:SCCRO3(display_short)|uniprotkb:Dmel\CG13322(gene name synonym)|uniprotkb:anon-WO0118547.137(gene name synonym)|uniprotkb:dSCCRO3(gene name synonym)|uniprotkb:CG13322(orf name)|uniprotkb:Dmel_CG13322(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111838|imex:IM-9552-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_610828.2|refseq:NP_725243.1|refseq:NP_725244.1|flybase:FBgn0033784|ensemblmetazoa:FBgn0033784(gene)|ensemblmetazoa:FBtr0087803(transcript)|ensemblmetazoa:FBtr0087804(transcript)|ensemblmetazoa:FBtr0087805(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045116"(protein neddylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000436"(positive regulation of protein neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|reactome:R-DME-8951664 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:VGw7PzFmaTfXuamPct5C5DVQAD07227 intact-crc:ADA2E6E7D0F718F5|rigid:J/wBTx7BBOTgFEufqmIIGNwTnlA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P92208 uniprotkb:O61444 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 intact:EBI-95608|uniprotkb:O61445|ensemblmetazoa:FBpp0081378|ensemblmetazoa:FBpp0289672|ensemblmetazoa:FBpp0306434 psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:o61444_drome(display_long)|uniprotkb:Mkk4(gene name)|psi-mi:Mkk4(display_short)|uniprotkb:P-MKK4(gene name synonym)|uniprotkb:142758_at(gene name synonym)|uniprotkb:CT27508(gene name synonym)|uniprotkb:D-MKK4(gene name synonym)|uniprotkb:DMKK4(gene name synonym)|uniprotkb:Dmel\CG9738(gene name synonym)|uniprotkb:JNKK2(gene name synonym)|uniprotkb:MAPKK4(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:Mpk4(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:dMKK4(gene name synonym)|uniprotkb:dMkk4(gene name synonym)|uniprotkb:mkk4(gene name synonym)|uniprotkb:Dmel_CG9738(orf name)|uniprotkb:CG9738(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111848|imex:IM-9552-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|ensemblmetazoa:FBgn0024326(gene)|ensemblmetazoa:FBtr0081892(transcript)|ensemblmetazoa:FBtr0300443(transcript)|ensemblmetazoa:FBtr0334320(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0048666"(neuron development)|interpro:IPR000719(Protein kinase, core)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0030424"(axon)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-2559580|refseq:NP_001163551.1|refseq:NP_477353.1|flybase:FBgn0024326|refseq:NP_001262375.1|reactome:R-DME-2871796|reactome:R-DME-450321 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 rogid:HldoJzQNkDXfKZR74vYg0dyj+CU7227 intact-crc:A36A9E68439A42F8|rigid:VcuAMd8oug3H/nNVeFjxil9Z6kw false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VRS0 uniprotkb:A1Z866 intact:EBI-146748|ensemblmetazoa:FBpp0076777 intact:EBI-148231|intact:EBI-2111446|ensemblmetazoa:FBpp0087427 psi-mi:q9vrs0_drome(display_long)|uniprotkb:Dmel\CG10478(gene name synonym)|uniprotkb:g7295403(gene name synonym)|uniprotkb:alphaKap4(gene name)|psi-mi:alphaKap4(display_short)|uniprotkb:aKap4(gene name synonym)|uniprotkb:CG11040(gene name synonym)|uniprotkb:CG10478(orf name)|uniprotkb:Dmel_CG10478(orf name) psi-mi:a1z866_drome(display_long)|uniprotkb:CAP(gene name)|psi-mi:CAP(display_short)|uniprotkb:CG18409(gene name synonym)|uniprotkb:CG3451(gene name synonym)|uniprotkb:DCAP(gene name synonym)|uniprotkb:Dmel\CG18408(gene name synonym)|uniprotkb:Rexin(gene name synonym)|uniprotkb:Vinexin(gene name synonym)|uniprotkb:cap(gene name synonym)|uniprotkb:rexin(gene name synonym)|uniprotkb:CG18408(orf name)|uniprotkb:Dmel_CG18408(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111828|imex:IM-9552-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648007.1|flybase:FBgn0035657|ensemblmetazoa:FBgn0035657(gene)|ensemblmetazoa:FBtr0077069(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|interpro:IPR024931 refseq:NP_610570.1|flybase:FBgn0033504|ensemblmetazoa:FBgn0033504(gene)|ensemblmetazoa:FBtr0088338(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0050954"(sensory perception of mechanical stimulus)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR036028 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:HenyM5gRG32k8a1xGQM26ru2Y/g7227 rogid:XEN75brprHfY4ZLb++9fGgcMr3A7227 intact-crc:97FDA47D1B6FE7D6|rigid:WL4aJc/L8QQYhxrTZ0XaAKMv5oE false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P23573 uniprotkb:Q8T6B9 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 intact:EBI-189756|uniprotkb:Q0E8J8|uniprotkb:Q95S11|uniprotkb:Q9U696|uniprotkb:Q9W0E6|uniprotkb:Q9W0E7|ensemblmetazoa:FBpp0072593 psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:puf68_drome(display_long)|uniprotkb:hfp(gene name)|psi-mi:hfp(display_short)|uniprotkb:"68 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:PUF60 homolog(gene name synonym)|uniprotkb:pUf68(gene name synonym)|uniprotkb:CG12085(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111833|imex:IM-9552-436 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N refseq:NP_001163315.1|refseq:NP_001163316.1|refseq:NP_001163317.1|refseq:NP_001163318.1|refseq:NP_001163319.1|refseq:NP_001163320.1|refseq:NP_525123.2|refseq:NP_728610.1|refseq:NP_728611.1|refseq:NP_728612.1|flybase:FBgn0028577|ensemblmetazoa:FBgn0028577(gene)|ensemblmetazoa:FBtr0072709(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007282"(cystoblast division)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|reactome:R-DME-72163 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 rogid:o/SLbHHagW4606ywhRrsIGnQeLk7227 intact-crc:AC0DD41243EE4C13|rigid:LPtfNFIOl/6hVxPxZYgTdxDkm8E false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8IRD1 uniprotkb:P40301 intact:EBI-2110941|ensemblmetazoa:FBpp0072937 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 psi-mi:q8ird1_drome(display_long)|uniprotkb:CG12010(orf name)|uniprotkb:Dmel_CG12010(orf name)|uniprotkb:Dmel\CG12010(gene name)|psi-mi:Dmel\CG12010(display_short) psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111863|imex:IM-9552-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_728878.1|flybase:FBgn0035443|ensemblmetazoa:FBgn0035443(gene)|ensemblmetazoa:FBtr0073075(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569 refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:Rh6SfHpRyRVROved1E/8sKuvF5c7227 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 intact-crc:CA2733B0D0450C63|rigid:HAtseYfEQKOowHJTCnf91Dwlc7c false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P48601 uniprotkb:Q05825 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 intact:EBI-86574|uniprotkb:Q9V494|ensemblmetazoa:FBpp0088250|ensemblmetazoa:FBpp0311086 psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:atpb_drome(display_long)|uniprotkb:ATPsynbeta(gene name)|psi-mi:ATPsynbeta(display_short)|uniprotkb:ATPsyn-beta(gene name synonym)|uniprotkb:CG11154(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111853|imex:IM-9552-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 ensemblmetazoa:FBgn0010217(gene)|ensemblmetazoa:FBtr0089186(transcript)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|ensemblmetazoa:FBtr0344754(transcript)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|go:"GO:0005524"(ATP binding)|interpro:IPR024034|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|interpro:IPR027417|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|interpro:IPR036121|reactome:R-DME-1268020|reactome:R-DME-163210|reactome:R-DME-8949613|refseq:NP_726631.1|flybase:FBgn0010217|refseq:NP_001284719.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 rogid:mLP/OfDa81Tk34znUkvi5OY+lzI7227 intact-crc:EEF32A648D4114AA|rigid:WrZ8Vpshop5klfYldQ9fkqsyEcA false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P05661 uniprotkb:P48601 intact:EBI-195031|uniprotkb:O18392|uniprotkb:O18393|uniprotkb:Q24412|uniprotkb:Q7JN62|uniprotkb:Q7JN63|uniprotkb:Q7JQ08|uniprotkb:Q7JQ09|uniprotkb:Q7M4K4|uniprotkb:Q8INZ9|uniprotkb:Q8IP00|uniprotkb:Q8IP01|uniprotkb:Q8IP02|uniprotkb:Q8IP03|uniprotkb:Q8IP04|uniprotkb:Q8IP05|uniprotkb:Q8IP06|uniprotkb:Q8IP07|uniprotkb:Q8IP08|uniprotkb:Q8IP09|uniprotkb:Q8IP10|uniprotkb:Q9TY21|uniprotkb:Q9TY22|uniprotkb:Q9TYD7|uniprotkb:Q9VJI3 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:mysa_drome(display_long)|uniprotkb:Mhc(gene name)|psi-mi:Mhc(display_short)|uniprotkb:CG17927(orf name) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111858|imex:IM-9552-440 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162991.1|refseq:NP_523587.4|refseq:NP_723999.1|refseq:NP_724000.1|refseq:NP_724001.1|refseq:NP_724003.1|refseq:NP_724004.1|refseq:NP_724005.1|refseq:NP_724006.1|refseq:NP_724007.1|refseq:NP_724008.1|refseq:NP_724009.1|refseq:NP_724010.1|refseq:NP_724002.2|flybase:FBgn0264695|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007517"(muscle organ development)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031033"(myosin filament organization)|go:"GO:0031672"(A band)|go:"GO:0040011"(locomotion)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060361"(flight)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P05661|rcsb pdb:5W1A refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:PjIC1oHiwbQEdum3SDZnk/b7O5E7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:DD4FD9D9E484FC7C|rigid:3RnzVWIOrYUK4Qy5TqSOsvlCtaI false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VM49 uniprotkb:Q8SZ19 intact:EBI-192082|intact:EBI-3436274|intact:EBI-466729|ensemblmetazoa:FBpp0088579|ensemblmetazoa:FBpp0088583 intact:EBI-2110884 psi-mi:q9vm49_drome(display_long)|uniprotkb:Caper(gene name)|psi-mi:Caper(display_short)|uniprotkb:CAPER(gene name synonym)|uniprotkb:CC1.3(gene name synonym)|uniprotkb:Dmel\CG11266(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:igru(gene name synonym)|uniprotkb:Dmel_CG11266(orf name)|uniprotkb:CG11266(orf name)|uniprotkb:cg11266(gene name synonym) psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111883|imex:IM-9552-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609095.1|refseq:NP_723243.1|flybase:FBgn0031883|ensemblmetazoa:FBgn0031883(gene)|ensemblmetazoa:FBtr0089636(transcript)|ensemblmetazoa:FBtr0089640(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979 flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:sfgpWrEZYmfdt5CLLjt85wjPitY7227 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 intact-crc:938EA0867AF57B48|rigid:Ln0BLXzY5siN9QfiJidbM76fnmc false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P18101 uniprotkb:Q9W418 intact:EBI-2111744|uniprotkb:P68198|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VZL4|uniprotkb:Q9VQX7|ensemblmetazoa:FBpp0077159|ensemblmetazoa:FBpp0306837 intact:EBI-114005|ensemblmetazoa:FBpp0070894|ensemblmetazoa:FBpp0311816 psi-mi:rl40_drome(display_long)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:UBI-F52(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:CG2960(orf name)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short) psi-mi:q9w418_drome(display_long)|uniprotkb:Ubi-p5E(gene name)|psi-mi:Ubi-p5E(display_short)|uniprotkb:CG32744(orf name)|uniprotkb:CG18282(gene name synonym)|uniprotkb:CR32744(gene name synonym)|uniprotkb:DmUbi-p5E(gene name synonym)|uniprotkb:Dmel\CG32744(gene name synonym)|uniprotkb:UB(gene name synonym)|uniprotkb:Ub(gene name synonym)|uniprotkb:Ubi(gene name synonym)|uniprotkb:Ubiq(gene name synonym)|uniprotkb:Dmel_CG32744(orf name)|uniprotkb:DmUb(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111868|imex:IM-9552-442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476776.1|flybase:FBgn0003941|refseq:NP_001260018.1|ensemblmetazoa:FBgn0003941(gene)|ensemblmetazoa:FBtr0077470(transcript)|ensemblmetazoa:FBtr0334787(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|rcsb pdb:4V6W|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-156827|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-1799339|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-201681|reactome:R-DME-209360|reactome:R-DME-209447|reactome:R-DME-209461|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689877|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-72689|reactome:R-DME-72706|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948747|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-912631|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-975956|reactome:R-DME-975957|reactome:R-DME-983168 ensemblmetazoa:FBgn0086558(gene)|ensemblmetazoa:FBtr0070933(transcript)|ensemblmetazoa:FBtr0345892(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|reactome:R-DME-5607761|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5358346|reactome:R-DME-5654733|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5675482|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689877|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-5689901|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6804757|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69231|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8849469|reactome:R-DME-8854050|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-901032|reactome:R-DME-9020702|reactome:R-DME-9033241|reactome:R-DME-912631|reactome:R-DME-917729|reactome:R-DME-917937|reactome:R-DME-9646399|reactome:R-DME-9648002|reactome:R-DME-983168|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948747|interpro:IPR019956|reactome:R-DME-195253|interpro:IPR029071|reactome:R-DME-201681|reactome:R-DME-209560|reactome:R-DME-2122948|reactome:R-DME-2173788|reactome:R-DME-110312|reactome:R-DME-110314|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-110320|reactome:R-DME-1234176|reactome:R-DME-1253288|reactome:R-DME-1295596|reactome:R-DME-1358803|reactome:R-DME-174048|reactome:R-DME-2559582|reactome:R-DME-3769402|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-382556|reactome:R-DME-174178|reactome:R-DME-450408|reactome:R-DME-174184|reactome:R-DME-179409|reactome:R-DME-4608870|reactome:R-DME-182971|reactome:R-DME-187577|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5205685|reactome:R-DME-532668|refseq:NP_727078.1|flybase:FBgn0086558|refseq:NP_001284937.1 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9vNVDJ3SvdO2vhXnOZV9lxLhgts7227 rogid:Nji68Fj8jQXcZi1dmH2WkapaGFU7227 intact-crc:7DCF5EA290F031D2|rigid:Nd3JmtAMPhthYhmiX9Fo3IGdUy0 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P55035 uniprotkb:P23696 intact:EBI-146479|uniprotkb:Q86R87|uniprotkb:Q9V473|ensemblmetazoa:FBpp0078024|ensemblmetazoa:FBpp0305644 intact:EBI-101960|uniprotkb:Q9VLW4|ensemblmetazoa:FBpp0079148|ensemblmetazoa:FBpp0310062|ensemblmetazoa:FBpp0310063 psi-mi:psmd4_drome(display_long)|uniprotkb:Rpn10(gene name)|psi-mi:Rpn10(display_short)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:54 kDa subunit of mu particle(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:PROS-54(gene name synonym)|uniprotkb:Pros54(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:CG7619(orf name) psi-mi:pp2a_drome(display_long)|uniprotkb:mts(gene name)|psi-mi:mts(display_short)|uniprotkb:PP2A(gene name synonym)|uniprotkb:Pp2A-28D(gene name synonym)|uniprotkb:CG7109(orf name)|uniprotkb:Protein microtubule star(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111873|imex:IM-9552-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524204.1|flybase:FBgn0015283|refseq:NP_001262168.1|dip:DIP-22777N|ensemblmetazoa:FBgn0015283(gene)|ensemblmetazoa:FBtr0078368(transcript)|ensemblmetazoa:FBtr0333453(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8939902 go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0009416"(response to light stimulus)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-DME-1295596|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-2995383|reactome:R-DME-389513|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-432626|reactome:R-DME-5673000|reactome:R-DME-5675221|reactome:R-DME-6811558|reactome:R-DME-69231|reactome:R-DME-69273|reactome:R-DME-975957|refseq:NP_001285724.1|refseq:NP_001285725.1|refseq:NP_476805.1|flybase:FBgn0004177|ensemblmetazoa:FBgn0004177(gene)|ensemblmetazoa:FBtr0079525(transcript)|ensemblmetazoa:FBtr0343416(transcript)|ensemblmetazoa:FBtr0343417(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|dip:DIP-17814N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:6bY+j4is8NW2IQHx1lviY1+oTuk7227 rogid:VLIsr3gJAP9LjcDE+7++cPMfs3A7227 intact-crc:DA7B9F1F0B326557|rigid:3IbMxpUuVPRaift6YgqdIbFbb1s false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P40301 uniprotkb:P49071 intact:EBI-98978|uniprotkb:Q9VG71|ensemblmetazoa:FBpp0082062 intact:EBI-118687|uniprotkb:Q9W480|ensemblmetazoa:FBpp0070802|ensemblmetazoa:FBpp0070804|ensemblmetazoa:FBpp0292066|ensemblmetazoa:FBpp0300801 psi-mi:psa2_drome(display_long)|uniprotkb:Prosalpha2(gene name)|psi-mi:Prosalpha2(display_short)|uniprotkb:PROS-25(gene name synonym)|uniprotkb:PROS-Dm25(gene name synonym)|uniprotkb:Pros25(gene name synonym)|uniprotkb:Proteasome 25 kDa subunit(gene name synonym)|uniprotkb:CG5266(orf name) psi-mi:mapk2_drome(display_long)|uniprotkb:MAPk-Ak2(gene name)|psi-mi:MAPk-Ak2(display_short)|uniprotkb:CG3086(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111878|imex:IM-9552-444 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524328.1|flybase:FBgn0086134|ensemblmetazoa:FBgn0086134(gene)|ensemblmetazoa:FBtr0082590(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|dip:DIP-20541N refseq:NP_001188547.1|refseq:NP_524769.1|refseq:NP_788861.1|flybase:FBgn0013987|ensemblmetazoa:FBgn0013987(gene)|ensemblmetazoa:FBtr0070837(transcript)|ensemblmetazoa:FBtr0070839(transcript)|ensemblmetazoa:FBtr0302940(transcript)|ensemblmetazoa:FBtr0308577(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009651"(response to salt stress)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0051019"(mitogen-activated protein kinase binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|reactome:R-DME-171007|reactome:R-DME-199920|reactome:R-DME-2559580|reactome:R-DME-3371453|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450385|reactome:R-DME-450513|refseq:NP_001245536.1|dip:DIP-21714N psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:/YcFIjUfc/41wWhV90Om4/CykzU7227 rogid:jOgW9S5IhMsBz2vBME8MBe9CyQI7227 intact-crc:120D01A0F52D3647|rigid:OCwvC+so/vmCAm/QjL0lqWdyDIQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SZ19 uniprotkb:P48601 intact:EBI-2110884 intact:EBI-189117|intact:EBI-1630917|uniprotkb:Q9VCG1|ensemblmetazoa:FBpp0083906|ensemblmetazoa:FBpp0311982 psi-mi:q8sz19_drome(display_long)|uniprotkb:CG3455(orf name)|uniprotkb:Rpt4(gene name)|psi-mi:Rpt4(display_short) psi-mi:prs4_drome(display_long)|uniprotkb:Rpt2(gene name)|psi-mi:Rpt2(display_short)|uniprotkb:P26s4(gene name synonym)|uniprotkb:Pros26.4(gene name synonym)|uniprotkb:CG5289(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111888|imex:IM-9552-446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028685|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569 refseq:NP_524469.2|flybase:FBgn0015282|refseq:NP_001287493.1|dip:DIP-17276N|ensemblmetazoa:FBgn0015282(gene)|ensemblmetazoa:FBtr0084520(transcript)|ensemblmetazoa:FBtr0346154(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:0NCtAHVJNGiQCf9h23y8CrwXZfw7227 rogid:t+ORyQjoUkCNBQjsQOGWhRO6kfI7227 intact-crc:1743C8E317D74C6C|rigid:omQXdwzgCFWWvcZchfcoUW5ULa4 false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9VHN1 uniprotkb:Q24159 intact:EBI-122930|intact:EBI-1629559|ensemblmetazoa:FBpp0307999|ensemblmetazoa:FBpp0081430|ensemblmetazoa:FBpp0293882 intact:EBI-455799|intact:EBI-1629390 psi-mi:q9vhn1_drome(display_long)|uniprotkb:Cks85A(gene name)|psi-mi:Cks85A(display_short)|uniprotkb:"BcDNA:GM01344"(gene name synonym)|uniprotkb:Cks(gene name synonym)|uniprotkb:Dmel\CG9790(gene name synonym)|uniprotkb:cks85A(gene name synonym)|uniprotkb:Dmel_CG9790(orf name)|uniprotkb:CG9790(orf name) psi-mi:q24159_drome(display_long)|uniprotkb:CycJ(gene name)|psi-mi:CycJ(display_short)|uniprotkb:CG10308(orf name) psi-mi:"MI:0397"(two hybrid array) Schwartz et al. (2009) imex:IM-9552|pubmed:19079254 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2111893|imex:IM-9552-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001246992.1|refseq:NP_649817.1|flybase:FBgn0037613|ensemblmetazoa:FBtr0081949(transcript)|ensemblmetazoa:FBtr0305339(transcript)|ensemblmetazoa:FBtr0337074(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|ensemblmetazoa:FBgn0037613(gene)|refseq:NP_001262383.1|dip:DIP-19136N flybase:FBgn0010317|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0060966"(regulation of gene silencing by RNA)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361 psi-mi:"MI:0469"(intact) - - comment:"Screen: Test of conservation-based predictions from Sharan 2005 PMID:15687504"|figure legend:Supplementary tables|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/11 2014/10/16 rogid:9cnk1EkPIw8WXpyxVLVnTgv9ZUI7227 rogid:v0+u1HylNkW8beHZZmGfAIjkczo7227 intact-crc:BBBE0826D592C5CA|rigid:P6tC6BrYC1P+daY0BT2nezj2zpQ false - - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing)