#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-2014933	uniprotkb:Q8U1N9	-	intact:EBI-2014945|ensemblbacteria:AAL81290	psi-mi:cacaagcttttgcttgtgac(display_short)|psi-mi:EBI-2014933(display_long)	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2014957|wwpdb:3dsc|imex:IM-12132-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	go:"GO:0003677"(DNA binding)	-	-	comment:The nucleic acid models a synaptic complex mimicking DNA end joining of products from a dsDNA scission event bearing a short 2 bp 3' overhang|3d-resolution:2.70A|3d-r-factors:working 22.8%, free 27.8%|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	crc64:E6652AC62DA76965	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	intact-crc:891B504DC8BA4967	false	-	sufficient binding region:1-342	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:29035"	intact:EBI-2014935	intact:EBI-1554638	-	psi-mi:"manganese(2+)"(display_short)|psi-mi:"CHEBI:29035"(display_long)	psi-mi:cgcgcacaagcttttgcttg(display_short)|psi-mi:EBI-2014935(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2014966|wwpdb:3dsd|imex:IM-12132-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0319"(deoxyribonucleic acid)	-	-	go:"GO:0003677"(DNA binding)	-	-	comment:The nucleic acid models a branched DNA structure that might be encountered by Mre11 at a collapsed fork|3d-resolution:2.20A|3d-r-factors:working 20.0%, free 24.6%|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	-	crc64:FBEC56738AC65E0F	intact-crc:93D9846027EC0FB3	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-2014935	uniprotkb:Q8U1N9	-	intact:EBI-2014945|ensemblbacteria:AAL81290	psi-mi:cgcgcacaagcttttgcttg(display_short)|psi-mi:EBI-2014935(display_long)	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2014966|wwpdb:3dsd|imex:IM-12132-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	go:"GO:0003677"(DNA binding)	-	-	comment:The nucleic acid models a branched DNA structure that might be encountered by Mre11 at a collapsed fork|3d-resolution:2.20A|3d-r-factors:working 20.0%, free 24.6%|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	crc64:FBEC56738AC65E0F	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	intact-crc:93D9846027EC0FB3	false	-	sufficient binding region:1-342	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1N9	uniprotkb:Q8U1N9	intact:EBI-2014945|ensemblbacteria:AAL81290	intact:EBI-2014945|ensemblbacteria:AAL81290	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:"MI:0071"(molecular sieving)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2014994|imex:IM-12132-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	go:"GO:0042803"(protein homodimerization activity)	-	-	figure legend:Fig. 3A, Supp. Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/10/20	2014/10/16	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	intact-crc:763BE781D391F77D|rigid:agNZ3gVHID3qZxV9jHz/m6MxSJI	false	mutation decreasing interaction:61-61,97-97	mutation decreasing interaction:61-61,97-97	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8U1N9	intact:EBI-2015044	intact:EBI-2014945|ensemblbacteria:AAL81290	-	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:ctcaagagcgcagataccaa(display_short)|psi-mi:EBI-2015044(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2015106|imex:IM-12132-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	-	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0003677"(DNA binding)	-	-	figure legend:Fig. 3F, Supp.Fig 3|comment:The point mutations in Ste11 prevent dimerization and reduce DNA binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	crc64:3F236AE633A0406F	intact-crc:8AD5E0C7BA5F2147	false	mutation decreasing interaction:61-61,97-97	-	2	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-2015035	intact:EBI-2015044	-	-	psi-mi:ctacactagaaggacagta(display_short)|psi-mi:EBI-2015035(display_long)	psi-mi:ctcaagagcgcagataccaa(display_short)|psi-mi:EBI-2015044(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2015124|imex:IM-12132-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0319"(deoxyribonucleic acid)	-	-	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0003677"(DNA binding)	-	-	figure legend:Fig. 3F, Supp. Fig. 3|comment:The point mutations in Ste11 prevent dimerization and reduce DNA binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	crc64:6D33AA296DE0103D	crc64:3F236AE633A0406F	intact-crc:34AC755774A83BE5	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-2015035	uniprotkb:Q8U1N9	-	intact:EBI-2014945|ensemblbacteria:AAL81290	psi-mi:ctacactagaaggacagta(display_short)|psi-mi:EBI-2015035(display_long)	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2015124|imex:IM-12132-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0003677"(DNA binding)	-	-	figure legend:Fig. 3F, Supp. Fig. 3|comment:The point mutations in Ste11 prevent dimerization and reduce DNA binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	crc64:6D33AA296DE0103D	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	intact-crc:34AC755774A83BE5	false	-	mutation decreasing interaction:61-61,97-97	-	2	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8U1N9	uniprotkb:Q8U1N9	intact:EBI-2014945|ensemblbacteria:AAL81290	intact:EBI-2014945|ensemblbacteria:AAL81290	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:"MI:0826"(x ray scattering)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2124707|imex:IM-12132-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	go:"GO:0042803"(protein homodimerization activity)	-	-	figure legend:Fig. 3D, Supp. Fig. 2|comment:SAXS analysis shows that Mre11-L61K and Mre11-L97D are converted to smaller forms.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/20	2014/10/16	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	intact-crc:C956B7D3CF463D59|rigid:agNZ3gVHID3qZxV9jHz/m6MxSJI	false	mutation decreasing interaction:61-61|mutation decreasing interaction:97-97	mutation decreasing interaction:61-61|mutation decreasing interaction:97-97	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q09683	uniprotkb:Q09683	intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep"	intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep"	psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name)	psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name)	psi-mi:"MI:0018"(two hybrid)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2124980|imex:IM-12132-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX	refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX	go:"GO:0042803"(protein homodimerization activity)	crc64:400B349EF4FA3428	crc64:400B349EF4FA3428	figure legend:Figs. 5A, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/20	2014/10/16	rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812	rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812	intact-crc:832D55E80B9CC215|rigid:0/5g+MG0xYj60LYNI+TzrK57SHY	false	mutation decreasing interaction:77-77|mutation decreasing interaction:154-154	mutation decreasing interaction:77-77|mutation decreasing interaction:154-154	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q09683	uniprotkb:O43070	intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep"	intact:EBI-2125045|uniprotkb:Q86ZQ0|ensemblfungi:"SPBC6B1.09c.1:pep"	psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name)	psi-mi:nbs1_schpo(display_long)|uniprotkb:nbs1(gene name)|psi-mi:nbs1(display_short)|uniprotkb:SPBC6B1.09c(orf name)	psi-mi:"MI:0018"(two hybrid)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2125077|imex:IM-12132-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX	refseq:NP_001018823.1|dip:DIP-52387N|reactome:R-SPO-2559586|reactome:R-SPO-5685939|reactome:R-SPO-5693548|reactome:R-SPO-5693565|ensemblfungi:SPBC6B1.09c(gene)|ensemblfungi:SPBC6B1.09c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|interpro:IPR040227|rcsb pdb:3HUE|rcsb pdb:3HUF|rcsb pdb:3I0M|rcsb pdb:3I0N|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW	go:"GO:0042803"(protein homodimerization activity)	crc64:400B349EF4FA3428	crc64:B3384CCC85F96DD1	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/20	2014/10/16	rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812	rogid:5h/qx0stPyVRQ9vtqO50Ftq0mvM284812	intact-crc:6BA288CD8D0C25BC|rigid:Utj9gdoZI/D5hITpWFf2sUUAaHs	false	mutation decreasing interaction:77-77,154-154	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q09683	uniprotkb:Q9UTJ8	intact:EBI-2124866|ensemblfungi:"SPAC13C5.07.1:pep"	intact:EBI-2125086|uniprotkb:Q9P3T5|ensemblfungi:"SPAC1556.01c.1:pep"	psi-mi:rad32_schpo(display_long)|uniprotkb:rad32(gene name)|psi-mi:rad32(display_short)|uniprotkb:SPAC13C5.07(orf name)	psi-mi:rad50_schpo(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:SPAC1556.01c(orf name)|uniprotkb:SPAP4C9.01c(orf name)	psi-mi:"MI:0018"(two hybrid)	Williams et al. (2008)	imex:IM-12132|pubmed:18854158	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2125112|imex:IM-12132-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_592935.1|reactome:R-SPO-1834949|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52388N|reactome:R-SPO-5685939|ensemblfungi:SPAC13C5.07(gene)|ensemblfungi:SPAC13C5.07.1(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0004518"(nuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|rcsb pdb:4FBK|rcsb pdb:4FBQ|rcsb pdb:4FBW|rcsb pdb:4FCX	refseq:XP_001713090.2|reactome:R-SPO-2559586|reactome:R-SPO-5693548|reactome:R-SPO-5693565|dip:DIP-52389N|reactome:R-SPO-5685939|ensemblfungi:SPAC1556.01c(gene)|ensemblfungi:SPAC1556.01c.1(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|go:"GO:0120290"(stalled replication fork localization to nuclear periphery)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903211"(mitotic recombination involved in replication fork processing)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|go:"GO:1990898"(meiotic DNA double-strand break clipping)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR004584(Recombination/repair protein Rad50)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729	go:"GO:0042803"(protein homodimerization activity)	crc64:400B349EF4FA3428	crc64:DF45B2EAE7097295	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/20	2014/10/16	rogid:FILmnrrlrq43tN0J4RzclGn79Ho284812	rogid:/h3u58m3i+rCJljt36veVoFiYFE284812	intact-crc:27431D920D930D83|rigid:JjtUlm+nUFoQMpIq89FQc6SsBbo	false	mutation decreasing interaction:77-77,154-154	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)