#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q4VBE4 uniprotkb:P39087 intact:EBI-2025048|uniprotkb:Q80WX4|uniprotkb:Q8BGP3|uniprotkb:B2RWU6|uniprotkb:B6JU28|ensembl:ENSMUSP00000094238 intact:EBI-396914|uniprotkb:Q60933|ensembl:ENSMUSP00000101124|ensembl:ENSMUSP00000151921 psi-mi:egfla_mouse(display_long)|uniprotkb:Egflam(gene name)|psi-mi:Egflam(display_short)|uniprotkb:EGF-like, fibronectin type-III and laminin G-like domain-containing protein(gene name synonym)|uniprotkb:Nectican(gene name synonym) psi-mi:grik2_mouse(display_long)|uniprotkb:Grik2(gene name)|psi-mi:Grik2(display_short)|uniprotkb:Glur6(gene name synonym)|uniprotkb:Glutamate receptor 6(gene name synonym)|uniprotkb:Glutamate receptor beta-2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Sato et al. (2008) pubmed:18641643|imex:IM-20144 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2025096|imex:IM-20144-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276425.1|refseq:XP_017172117.1|refseq:NP_848863.1|ensembl:ENSMUSG00000042961(gene)|ensembl:ENSMUST00000096494(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005614"(interstitial matrix)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0043083"(synaptic cleft)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116 refseq:XP_017169293.1|ensembl:ENSMUSG00000056073(gene)|ensembl:ENSMUST00000105484(transcript)|ensembl:ENSMUST00000218823(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|mint:P39087|reactome:R-MMU-451307|reactome:R-MMU-451308 - - - figure legend:2|comment:"Partial colocalization occurs in retina ON bipolar cells outer plexiform layers (OPLs) postsynaptic sites of the ribbon synapses."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2008/10/23 2014/10/16 rogid:4HMU4/rUDXwTUdVF4m176LXbpvg10090 rogid:6sgY8SzX07HzilLLeDg3pV+sXkc10090 intact-crc:062B8401ABCF9194|rigid:trJngCHZ9SUTfoi/F4Tm/HjnncU false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q4VBE4 uniprotkb:P56546 intact:EBI-2025048|uniprotkb:Q80WX4|uniprotkb:Q8BGP3|uniprotkb:B2RWU6|uniprotkb:B6JU28|ensembl:ENSMUSP00000094238 intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269 psi-mi:egfla_mouse(display_long)|uniprotkb:Egflam(gene name)|psi-mi:Egflam(display_short)|uniprotkb:EGF-like, fibronectin type-III and laminin G-like domain-containing protein(gene name synonym)|uniprotkb:Nectican(gene name synonym) psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short) psi-mi:"MI:0663"(confocal microscopy) Sato et al. (2008) pubmed:18641643|imex:IM-20144 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2025143|imex:IM-20144-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276425.1|refseq:XP_017172117.1|refseq:NP_848863.1|ensembl:ENSMUSG00000042961(gene)|ensembl:ENSMUST00000096494(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005614"(interstitial matrix)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0043083"(synaptic cleft)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116 refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265 - - - figure legend:2|comment:"Colocalization occurs in retina outer plexiform layers (OPLs) ribbon synapses."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2008/10/23 2014/10/16 rogid:4HMU4/rUDXwTUdVF4m176LXbpvg10090 rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090 intact-crc:CC294E043F1BD558|rigid:43gAYB3b8KHRMTn+3/5UC/XVjTU false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q4VBE4 uniprotkb:Q62165-PRO_0000021068 intact:EBI-2025048|uniprotkb:Q80WX4|uniprotkb:Q8BGP3|uniprotkb:B2RWU6|uniprotkb:B6JU28|ensembl:ENSMUSP00000094238 intact:EBI-2025181 psi-mi:egfla_mouse(display_long)|uniprotkb:Egflam(gene name)|psi-mi:Egflam(display_short)|uniprotkb:EGF-like, fibronectin type-III and laminin G-like domain-containing protein(gene name synonym)|uniprotkb:Nectican(gene name synonym) psi-mi:q62165-pro_0000021068(display_long)|uniprotkb:Dag1(gene name)|psi-mi:Dag1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Sato et al. (2008) pubmed:18641643|imex:IM-20144 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2025207|imex:IM-20144-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276425.1|refseq:XP_017172117.1|refseq:NP_848863.1|ensembl:ENSMUSG00000042961(gene)|ensembl:ENSMUST00000096494(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005614"(interstitial matrix)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0043083"(synaptic cleft)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116 intact:EBI-2878952(chain-parent) - - chain-seq-start:652|chain-seq-end:893 comment:"Colocalization occurs in retina outer plexiform layers (OPLs)."|figure legend:6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2008/10/23 2014/10/16 rogid:4HMU4/rUDXwTUdVF4m176LXbpvg10090 rogid:x+xuKHc/j4oaI1AC74rCT+FxVAs10090 intact-crc:F7680C4B912B8A20|rigid:RDgmv9ztQJgceptNVS8e5ormzCc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q4VBE4 uniprotkb:P11531 intact:EBI-2025048|uniprotkb:Q80WX4|uniprotkb:Q8BGP3|uniprotkb:B2RWU6|uniprotkb:B6JU28|ensembl:ENSMUSP00000094238 intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0 psi-mi:egfla_mouse(display_long)|uniprotkb:Egflam(gene name)|psi-mi:Egflam(display_short)|uniprotkb:EGF-like, fibronectin type-III and laminin G-like domain-containing protein(gene name synonym)|uniprotkb:Nectican(gene name synonym) psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short) psi-mi:"MI:0663"(confocal microscopy) Sato et al. (2008) pubmed:18641643|imex:IM-20144 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2025212|imex:IM-20144-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276425.1|refseq:XP_017172117.1|refseq:NP_848863.1|ensembl:ENSMUSG00000042961(gene)|ensembl:ENSMUST00000096494(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005614"(interstitial matrix)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0043083"(synaptic cleft)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116 go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N - - - figure legend:6|comment:"Colocalization occurs in retina outer plexiform layers (OPLs)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2008/10/23 2014/10/16 rogid:4HMU4/rUDXwTUdVF4m176LXbpvg10090 rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090 intact-crc:177A6EC66E16C8DC|rigid:hVAR7RuFuJTKe0s7FyjUCCcFBtc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q62165-PRO_0000021067 uniprotkb:Q4VBE4 intact:EBI-2025154 intact:EBI-2025048|uniprotkb:Q80WX4|uniprotkb:Q8BGP3|uniprotkb:B2RWU6|uniprotkb:B6JU28|ensembl:ENSMUSP00000094238 psi-mi:q62165-pro_0000021067(display_long)|uniprotkb:Dag1(gene name)|psi-mi:Dag1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:egfla_mouse(display_long)|uniprotkb:Egflam(gene name)|psi-mi:Egflam(display_short)|uniprotkb:EGF-like, fibronectin type-III and laminin G-like domain-containing protein(gene name synonym)|uniprotkb:Nectican(gene name synonym) psi-mi:"MI:0096"(pull down) Sato et al. (2008) pubmed:18641643|imex:IM-20144 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2025109|imex:IM-20144-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2878952(chain-parent) refseq:NP_001276425.1|refseq:XP_017172117.1|refseq:NP_848863.1|ensembl:ENSMUSG00000042961(gene)|ensembl:ENSMUST00000096494(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005614"(interstitial matrix)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0043083"(synaptic cleft)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116 - chain-seq-start:28|chain-seq-end:651 - figure legend:6g and h|inhibition:EDTA. In presence of EDTA the interaction was not observed.|comment:"The interaction was observed in presence of Ca(2+) and Mg(2+)."|antagonist:IIH6. In presence of the alpha-dystroglycan antibody IIH6 the interaction was not observed.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/10/23 2014/10/16 rogid:yw9T5osxwHgGbNLeFEeUpj/20lA10090 rogid:4HMU4/rUDXwTUdVF4m176LXbpvg10090 intact-crc:1C4651FE7D05D974|rigid:eYjOh54Ng2wRSefb/AB9CZHLfZ4 false tag:?-? binding-associated region:391-1017|his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q62165-PRO_0000021067 uniprotkb:Q4VBE4 intact:EBI-2025154 intact:EBI-2025048|uniprotkb:Q80WX4|uniprotkb:Q8BGP3|uniprotkb:B2RWU6|uniprotkb:B6JU28|ensembl:ENSMUSP00000094238 psi-mi:q62165-pro_0000021067(display_long)|uniprotkb:Dag1(gene name)|psi-mi:Dag1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:egfla_mouse(display_long)|uniprotkb:Egflam(gene name)|psi-mi:Egflam(display_short)|uniprotkb:EGF-like, fibronectin type-III and laminin G-like domain-containing protein(gene name synonym)|uniprotkb:Nectican(gene name synonym) psi-mi:"MI:0096"(pull down) Sato et al. (2008) pubmed:18641643|imex:IM-20144 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2025168|imex:IM-20144-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2878952(chain-parent) refseq:NP_001276425.1|refseq:XP_017172117.1|refseq:NP_848863.1|ensembl:ENSMUSG00000042961(gene)|ensembl:ENSMUST00000096494(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005614"(interstitial matrix)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019800"(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0043083"(synaptic cleft)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116 - chain-seq-start:28|chain-seq-end:651 - figure legend:6i|inhibition:EDTA. In presence of EDTA the interaction was not observed.|comment:"The interaction was observed in presence of Ca(2+) and Mg(2+)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/10/23 2014/10/16 rogid:yw9T5osxwHgGbNLeFEeUpj/20lA10090 rogid:4HMU4/rUDXwTUdVF4m176LXbpvg10090 intact-crc:515ADA1A9BDF4340|rigid:eYjOh54Ng2wRSefb/AB9CZHLfZ4 false - binding-associated region:391-1017 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)