#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P36404	uniprotkb:Q13432	intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021	intact:EBI-711260|uniprotkb:O95126|ensembl:ENSP00000337040|uniprotkb:F1T095|uniprotkb:A8K8G4	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:u119a_human(display_long)|uniprotkb:UNC119(gene name)|psi-mi:UNC119(display_short)|uniprotkb:RG4(gene name synonym)|uniprotkb:Retinal protein 4(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996677|mint:MINT-6602204|imex:IM-14077-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|mint:MINT-6602208(identity)	refseq:NP_005139.1|refseq:NP_473376.1|ensembl:ENSG00000109103(gene)|ensembl:ENST00000335765(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008289"(lipid binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032977|interpro:IPR037036|mint:Q13432|rcsb pdb:3GQQ|rcsb pdb:3RBQ|rcsb pdb:4GOJ|rcsb pdb:4GOK|rcsb pdb:5L7K|rcsb pdb:6H6A|refseq:NP_001317095.1|dip:DIP-42697N|mint:MINT-6602206(identity)	-	-	-	figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	rogid:y4vN846RQ9HzsRTMST/eac5d1Rc9606	intact-crc:54F8F9EDED4C7A9C|rigid:qq4TfCxP2Iq0pC1/TqIFCsRM0EY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43924	uniprotkb:P36404	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996648|mint:MINT-6602195|imex:IM-14077-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N|mint:MINT-6602198(identity)	refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|mint:MINT-6602197(identity)	-	-	-	figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	intact-crc:17ABFE9900F25282|rigid:dnKoKSlTcP7VsYzz1UNp+X8umkA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WZ55	uniprotkb:P36404	intact:EBI-7996695|intact:MINT-4536104|uniprotkb:Q6NT28|ensembl:ENSP00000498282	intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021	psi-mi:bsnd_human(display_long)|uniprotkb:BSND(gene name)|psi-mi:BSND(display_short)|uniprotkb:BART(gene name synonym)	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996689|mint:MINT-6602213|imex:IM-14077-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476517.1|ensembl:ENSG00000162399(gene)|ensembl:ENST00000651561(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0032991"(protein-containing complex)|interpro:IPR029181|mint:Q8WZ55|reactome:R-HSA-2672351|mint:MINT-6602215(identity)	refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|mint:MINT-6602217(identity)	-	comment:mint|function:Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter|function:"Defects in BSND are the cause of Bartter syndrome type 4 (BS4) [MIM:602522]; also known as infantile Bartter syndrome with sensorineural deafness. BS refers to a group of autosomal recessive disorders characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. BS4 is associated with sensorineural deafness"	-	figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:mTzIUQyaEiIx0Yna0Ze52JqL2FM9606	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	intact-crc:4F10B9E812A580CA|rigid:tdkR7aWfzeJITMUclmbrbOpzOUk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:O43924	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996721|mint:MINT-6602227|imex:IM-14077-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602231(identity)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N|mint:MINT-6602229(identity)	-	-	-	figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:BA4300E37EF73566|rigid:bkxdKxi4A8i0wh9vxcJHiDvjOGk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WZ55	uniprotkb:P36405	intact:EBI-7996695|intact:MINT-4536104|uniprotkb:Q6NT28|ensembl:ENSP00000498282	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	psi-mi:bsnd_human(display_long)|uniprotkb:BSND(gene name)|psi-mi:BSND(display_short)|uniprotkb:BART(gene name synonym)	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996745|mint:MINT-6602239|imex:IM-14077-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476517.1|ensembl:ENSG00000162399(gene)|ensembl:ENST00000651561(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0032991"(protein-containing complex)|interpro:IPR029181|mint:Q8WZ55|reactome:R-HSA-2672351|mint:MINT-6602241(identity)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602243(identity)	-	comment:mint|function:Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter|function:"Defects in BSND are the cause of Bartter syndrome type 4 (BS4) [MIM:602522]; also known as infantile Bartter syndrome with sensorineural deafness. BS refers to a group of autosomal recessive disorders characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. BS4 is associated with sensorineural deafness"	-	figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:mTzIUQyaEiIx0Yna0Ze52JqL2FM9606	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	intact-crc:C3E04B896C18CA94|rigid:8gCfUvR8gi0QYUXojYpf+qnb0XA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:Q8IWN7	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-1757848|uniprotkb:Q86SQ1|uniprotkb:Q8IWN8|uniprotkb:Q8IWN9|uniprotkb:Q8IWP0|uniprotkb:Q8IWP1|uniprotkb:Q8IWP2|uniprotkb:A6NKC6|ensembl:ENSP00000371923	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:rp1l1_human(display_long)|uniprotkb:RP1L1(gene name)|psi-mi:RP1L1(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996757|mint:MINT-6602258|imex:IM-14077-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602260(identity)	refseq:NP_849188.4|ensembl:ENSG00000183638(gene)|ensembl:ENST00000382483(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035082"(axoneme assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR003533(Doublecortin)|interpro:IPR036572|interpro:IPR040163|mint:Q8IWN7|mint:MINT-6602262(identity)	-	-	-	figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2018/04/06	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:ve6GxktAIeGfEbXNg5F0NJbzO5Y9606	intact-crc:923BBAC339F7A987|rigid:9hTOyHL6Is/AnLJi0FDhqAHouxo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:Q13432	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-711260|uniprotkb:O95126|ensembl:ENSP00000337040|uniprotkb:F1T095|uniprotkb:A8K8G4	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:u119a_human(display_long)|uniprotkb:UNC119(gene name)|psi-mi:UNC119(display_short)|uniprotkb:RG4(gene name synonym)|uniprotkb:Retinal protein 4(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996733|mint:MINT-6602233|imex:IM-14077-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602237(identity)	refseq:NP_005139.1|refseq:NP_473376.1|ensembl:ENSG00000109103(gene)|ensembl:ENST00000335765(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008289"(lipid binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032977|interpro:IPR037036|mint:Q13432|rcsb pdb:3GQQ|rcsb pdb:3RBQ|rcsb pdb:4GOJ|rcsb pdb:4GOK|rcsb pdb:5L7K|rcsb pdb:6H6A|refseq:NP_001317095.1|dip:DIP-42697N|mint:MINT-6602235(identity)	-	-	-	figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:y4vN846RQ9HzsRTMST/eac5d1Rc9606	intact-crc:3C9CDDEDFC82BCB1|rigid:842ZeVtBR7ZJ3WMPJ4AzgfwAIg8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:Q13432	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-711260|uniprotkb:O95126|ensembl:ENSP00000337040|uniprotkb:F1T095|uniprotkb:A8K8G4	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:u119a_human(display_long)|uniprotkb:UNC119(gene name)|psi-mi:UNC119(display_short)|uniprotkb:RG4(gene name synonym)|uniprotkb:Retinal protein 4(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996871|mint:MINT-6602369|imex:IM-14077-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602373(identity)	refseq:NP_005139.1|refseq:NP_473376.1|ensembl:ENSG00000109103(gene)|ensembl:ENST00000335765(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008289"(lipid binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032977|interpro:IPR037036|mint:Q13432|rcsb pdb:3GQQ|rcsb pdb:3RBQ|rcsb pdb:4GOJ|rcsb pdb:4GOK|rcsb pdb:5L7K|rcsb pdb:6H6A|refseq:NP_001317095.1|dip:DIP-42697N|mint:MINT-6602371(identity)	-	-	-	kinetics:kd 28 nanomolar|figure legend:5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:y4vN846RQ9HzsRTMST/eac5d1Rc9606	intact-crc:6AEFE2DA111FFBFE|rigid:CYSjCnWFOml8LZQnEoqO1pJZPCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:O75695	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-7996807|uniprotkb:Q9NU67|uniprotkb:Q86XJ7|intact:MINT-5003911|ensembl:ENSP00000218340	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:xrp2_human(display_long)|uniprotkb:RP2(gene name)|psi-mi:RP2(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996871|mint:MINT-6602369|imex:IM-14077-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602373(identity)	refseq:NP_008846.2|dip:DIP-29024N|ensembl:ENSG00000102218(gene)|ensembl:ENST00000218340(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR006599(CARP motif)|interpro:IPR012945(Tubulin binding cofactor C)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR036223|interpro:IPR036850|interpro:IPR039093|mint:O75695|rcsb pdb:2BX6|rcsb pdb:3BH6|rcsb pdb:3BH7|reactome:R-HSA-5624138|mint:MINT-6602375(identity)	-	-	comment:mint|function:Stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor for ARL3|function:"Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:312600]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well"	kinetics:kd 28 nanomolar|figure legend:5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:34VzWqa5cV0XAIxDOCDGzd+1VPk9606	intact-crc:6AEFE2DA111FFBFE|rigid:CYSjCnWFOml8LZQnEoqO1pJZPCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:Q13432	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-711260|uniprotkb:O95126|ensembl:ENSP00000337040|uniprotkb:F1T095|uniprotkb:A8K8G4	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:u119a_human(display_long)|uniprotkb:UNC119(gene name)|psi-mi:UNC119(display_short)|uniprotkb:RG4(gene name synonym)|uniprotkb:Retinal protein 4(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996801|mint:MINT-6602347|imex:IM-14077-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602350(identity)	refseq:NP_005139.1|refseq:NP_473376.1|ensembl:ENSG00000109103(gene)|ensembl:ENST00000335765(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008289"(lipid binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032977|interpro:IPR037036|mint:Q13432|rcsb pdb:3GQQ|rcsb pdb:3RBQ|rcsb pdb:4GOJ|rcsb pdb:4GOK|rcsb pdb:5L7K|rcsb pdb:6H6A|refseq:NP_001317095.1|dip:DIP-42697N|mint:MINT-6602349(identity)	-	-	-	figure legend:3A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:y4vN846RQ9HzsRTMST/eac5d1Rc9606	intact-crc:3F6B432AB00562BE|rigid:CYSjCnWFOml8LZQnEoqO1pJZPCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:O75695	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-7996807|uniprotkb:Q9NU67|uniprotkb:Q86XJ7|intact:MINT-5003911|ensembl:ENSP00000218340	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:xrp2_human(display_long)|uniprotkb:RP2(gene name)|psi-mi:RP2(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996801|mint:MINT-6602347|imex:IM-14077-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602350(identity)	refseq:NP_008846.2|dip:DIP-29024N|ensembl:ENSG00000102218(gene)|ensembl:ENST00000218340(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR006599(CARP motif)|interpro:IPR012945(Tubulin binding cofactor C)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR036223|interpro:IPR036850|interpro:IPR039093|mint:O75695|rcsb pdb:2BX6|rcsb pdb:3BH6|rcsb pdb:3BH7|reactome:R-HSA-5624138|mint:MINT-6602351(identity)	-	-	comment:mint|function:Stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor for ARL3|function:"Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:312600]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well"	figure legend:3A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:34VzWqa5cV0XAIxDOCDGzd+1VPk9606	intact-crc:3F6B432AB00562BE|rigid:CYSjCnWFOml8LZQnEoqO1pJZPCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13432	uniprotkb:P36404	intact:EBI-711260|uniprotkb:O95126|ensembl:ENSP00000337040|uniprotkb:F1T095|uniprotkb:A8K8G4	intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021	psi-mi:u119a_human(display_long)|uniprotkb:UNC119(gene name)|psi-mi:UNC119(display_short)|uniprotkb:RG4(gene name synonym)|uniprotkb:Retinal protein 4(gene name synonym)	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:"MI:0096"(pull down)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996913|mint:MINT-6602303|imex:IM-14077-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005139.1|refseq:NP_473376.1|ensembl:ENSG00000109103(gene)|ensembl:ENST00000335765(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008289"(lipid binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032977|interpro:IPR037036|mint:Q13432|rcsb pdb:3GQQ|rcsb pdb:3RBQ|rcsb pdb:4GOJ|rcsb pdb:4GOK|rcsb pdb:5L7K|rcsb pdb:6H6A|refseq:NP_001317095.1|dip:DIP-42697N|mint:MINT-6602305(identity)	refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|mint:MINT-6602307(identity)	-	-	-	figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:y4vN846RQ9HzsRTMST/eac5d1Rc9606	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	intact-crc:C4DCE9B533BEA4A9|rigid:qq4TfCxP2Iq0pC1/TqIFCsRM0EY	false	-	his tag:?-?(MINT-6602318)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P36404	uniprotkb:O43924	intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0096"(pull down)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996898|mint:MINT-6602297|imex:IM-14077-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|mint:MINT-6602301(identity)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N|mint:MINT-6602299(identity)	-	-	-	figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:2FB39163D1AA104B|rigid:dnKoKSlTcP7VsYzz1UNp+X8umkA	false	his tag:?-?(MINT-6602310)	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9BTW9	uniprotkb:P36405	intact:EBI-356005|uniprotkb:O95458|uniprotkb:Q7L8K1|uniprotkb:Q8IXP6|uniprotkb:Q8NAX0|uniprotkb:Q8WYH4|uniprotkb:Q96E74|uniprotkb:Q9UF82|uniprotkb:Q9UG46|uniprotkb:Q9Y2J3|intact:EBI-2555162|intact:EBI-2562220|ensembl:ENSP00000347719	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	psi-mi:tbcd_human(display_long)|uniprotkb:TBCD(gene name)|psi-mi:TBCD(display_short)|uniprotkb:KIAA0988(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:TFCD(gene name synonym)|uniprotkb:PP1096(orf name)|uniprotkb:Tubulin-folding cofactor D(gene name synonym)|uniprotkb:Beta-tubulin cofactor D(gene name synonym)|uniprotkb:SSD-1(gene name synonym)	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996960|mint:MINT-6602333|imex:IM-14077-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005984.3|ensembl:ENSG00000141556(gene)|ensembl:ENST00000355528(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0051087"(chaperone binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022577|interpro:IPR033162|mint:Q9BTW9|reactome:R-HSA-389977|mint:MINT-6602335(identity)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602337(identity)	-	-	-	figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:9idLpkQy9EORh88FUMLul3LU3Yg9606	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	intact-crc:C7A8A7EEC30BBE3D|rigid:n5httCOm11+D1DrZrs+huqZ9+As	false	-	his tag:?-?(MINT-6602338)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9BTW9	uniprotkb:P36404	intact:EBI-356005|uniprotkb:O95458|uniprotkb:Q7L8K1|uniprotkb:Q8IXP6|uniprotkb:Q8NAX0|uniprotkb:Q8WYH4|uniprotkb:Q96E74|uniprotkb:Q9UF82|uniprotkb:Q9UG46|uniprotkb:Q9Y2J3|intact:EBI-2555162|intact:EBI-2562220|ensembl:ENSP00000347719	intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021	psi-mi:tbcd_human(display_long)|uniprotkb:TBCD(gene name)|psi-mi:TBCD(display_short)|uniprotkb:KIAA0988(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:TFCD(gene name synonym)|uniprotkb:PP1096(orf name)|uniprotkb:Tubulin-folding cofactor D(gene name synonym)|uniprotkb:Beta-tubulin cofactor D(gene name synonym)|uniprotkb:SSD-1(gene name synonym)	psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short)	psi-mi:"MI:0096"(pull down)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996928|mint:MINT-6602322|imex:IM-14077-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005984.3|ensembl:ENSG00000141556(gene)|ensembl:ENST00000355528(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0051087"(chaperone binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022577|interpro:IPR033162|mint:Q9BTW9|reactome:R-HSA-389977|mint:MINT-6602324(identity)	refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002|mint:MINT-6602326(identity)	-	-	-	figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:9idLpkQy9EORh88FUMLul3LU3Yg9606	rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606	intact-crc:07F4A6FBBF10710C|rigid:UckwsSkMZTccg3sGe9e4zROaXVo	false	-	his tag:?-?(MINT-6602327)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P36405	uniprotkb:Q13432	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-711260|uniprotkb:O95126|ensembl:ENSP00000337040|uniprotkb:F1T095|uniprotkb:A8K8G4	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:u119a_human(display_long)|uniprotkb:UNC119(gene name)|psi-mi:UNC119(display_short)|uniprotkb:RG4(gene name synonym)|uniprotkb:Retinal protein 4(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996986|mint:MINT-6602360|imex:IM-14077-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602364(identity)	refseq:NP_005139.1|refseq:NP_473376.1|ensembl:ENSG00000109103(gene)|ensembl:ENST00000335765(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008289"(lipid binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0051233"(spindle midzone)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032977|interpro:IPR037036|mint:Q13432|rcsb pdb:3GQQ|rcsb pdb:3RBQ|rcsb pdb:4GOJ|rcsb pdb:4GOK|rcsb pdb:5L7K|rcsb pdb:6H6A|refseq:NP_001317095.1|dip:DIP-42697N|mint:MINT-6602366(identity)	-	-	-	figure legend:3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:y4vN846RQ9HzsRTMST/eac5d1Rc9606	intact-crc:EB01BECB7338F83F|rigid:CYSjCnWFOml8LZQnEoqO1pJZPCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36405	uniprotkb:O75695	intact:EBI-712710|uniprotkb:Q5JSM2|ensembl:ENSP00000260746|uniprotkb:B2R6C7|uniprotkb:Q53X83	intact:EBI-7996807|uniprotkb:Q9NU67|uniprotkb:Q86XJ7|intact:MINT-5003911|ensembl:ENSP00000218340	psi-mi:arl3_human(display_long)|uniprotkb:ARL3(gene name)|psi-mi:ARL3(display_short)|uniprotkb:ARFL3(gene name synonym)	psi-mi:xrp2_human(display_long)|uniprotkb:RP2(gene name)|psi-mi:RP2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Veltel et al. (2008)	pubmed:18588884|imex:IM-14077|mint:MINT-6602175	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7996986|mint:MINT-6602360|imex:IM-14077-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000138175(gene)|ensembl:ENST00000260746(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36405|reactome:R-HSA-5624138|refseq:NP_004302.1|refseq:XP_016871749.1|dip:DIP-47537N|mint:MINT-6602364(identity)	refseq:NP_008846.2|dip:DIP-29024N|ensembl:ENSG00000102218(gene)|ensembl:ENST00000218340(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR006599(CARP motif)|interpro:IPR012945(Tubulin binding cofactor C)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR036223|interpro:IPR036850|interpro:IPR039093|mint:O75695|rcsb pdb:2BX6|rcsb pdb:3BH6|rcsb pdb:3BH7|reactome:R-HSA-5624138|mint:MINT-6602362(identity)	-	-	comment:mint|function:Stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor for ARL3|function:"Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:312600]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well"	figure legend:3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/10	2014/10/16	rogid:qX6++/sQKD5KXgYUVt05ye2JpDc9606	rogid:34VzWqa5cV0XAIxDOCDGzd+1VPk9606	intact-crc:EB01BECB7338F83F|rigid:CYSjCnWFOml8LZQnEoqO1pJZPCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)