#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ERC8 uniprotkb:Q90922 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0096"(pull down) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1798621|imex:IM-12061-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3B, 3G|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:C5C15AF23B1DF8C7|rigid:leRLZC3B9Hb5iNvYsNad50kliM0 false fusion protein:n-n|sufficient binding region:593-883 myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P16056 uniprotkb:P14210 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1798811|imex:IM-12061-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 intact-crc:CCC823318B795E79|rigid:o+Enl0PGOuErA3nChuPpTxYxcug false myc tag:c-c|35s radiolabel:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P14210 uniprotkb:P16056 intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1798827|imex:IM-12061-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 intact-crc:83658301D8D5F6A0|rigid:o+Enl0PGOuErA3nChuPpTxYxcug false - myc tag:c-c|35s radiolabel:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O09118 uniprotkb:P70211 intact:EBI-1798844|uniprotkb:B1ARR0|uniprotkb:Q60832|uniprotkb:Q9QY50|ensembl:ENSMUSP00000021284|ensembl:ENSMUSP00000104314 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 psi-mi:net1_mouse(display_long)|uniprotkb:Ntn1(gene name)|psi-mi:Ntn1(display_short) psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1798899|imex:IM-12061-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032770.2|ensembl:ENSMUSG00000020902(gene)|ensembl:ENSMUST00000021284(transcript)|ensembl:ENSMUST00000108674(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007097"(nuclear migration)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030879"(mammary gland development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071944"(cell periphery)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|rcsb pdb:4OVE|reactome:R-MMU-373752|reactome:R-MMU-418885 refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:03RX6IHBOrGA1HJPLlszlp+P6i410090 rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 intact-crc:716AF6D131F5058F|rigid:2OJnmoF1rXd1Q211dVN3VN0aRcE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ERC8 uniprotkb:O09118 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798844|uniprotkb:B1ARR0|uniprotkb:Q60832|uniprotkb:Q9QY50|ensembl:ENSMUSP00000021284|ensembl:ENSMUSP00000104314 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_mouse(display_long)|uniprotkb:Ntn1(gene name)|psi-mi:Ntn1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1798904|imex:IM-12061-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) refseq:NP_032770.2|ensembl:ENSMUSG00000020902(gene)|ensembl:ENSMUST00000021284(transcript)|ensembl:ENSMUST00000108674(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007097"(nuclear migration)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030879"(mammary gland development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071944"(cell periphery)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|rcsb pdb:4OVE|reactome:R-MMU-373752|reactome:R-MMU-418885 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:03RX6IHBOrGA1HJPLlszlp+P6i410090 intact-crc:F2A07FB14433FA79|rigid:zhHt4zJr5eS/eZgjzZjQidPS6ic false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70211 uniprotkb:Q9ERC8 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 intact:EBI-1798601|ensembl:ENSMUSP00000056040 psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799167|imex:IM-12061-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 intact-crc:828F9FB915F96B11|rigid:I3/lxMT+cvX8xfrHidFUe/yNh+U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70211 uniprotkb:Q9ERC8 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 intact:EBI-1798601|ensembl:ENSMUSP00000056040 psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799172|imex:IM-12061-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 intact-crc:733040817D91FF29|rigid:I3/lxMT+cvX8xfrHidFUe/yNh+U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70211 uniprotkb:Q90922 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 intact:EBI-1798593 psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799181|imex:IM-12061-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:CD3317C21E100DCA|rigid:xS8UmGvakZayCgbHp+WRpazIKZo false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70211 uniprotkb:Q9ERC8 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 intact:EBI-1798601|ensembl:ENSMUSP00000056040 psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799181|imex:IM-12061-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 intact-crc:CD3317C21E100DCA|rigid:xS8UmGvakZayCgbHp+WRpazIKZo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ERC8 uniprotkb:Q90922 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799190|imex:IM-12061-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:1D67AABC72DA35CB|rigid:xS8UmGvakZayCgbHp+WRpazIKZo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ERC8 uniprotkb:P70211 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799190|imex:IM-12061-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-spinal-cord)|taxid:10090(Mouse spinal cord) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 intact-crc:1D67AABC72DA35CB|rigid:xS8UmGvakZayCgbHp+WRpazIKZo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q90922 uniprotkb:Q9ERC8 intact:EBI-1798593 intact:EBI-1798601|ensembl:ENSMUSP00000056040 psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1798956|imex:IM-12061-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) go:"GO:0005102"(signaling receptor binding) - - figure legend:Fig. 3A|caution:The methods and materials describe Netrin-1 as a myc construct, the text as an Fc construct. This has been annotated as a myc-construct as there is no description elsewhere of the protein as an Fc construct.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 intact-crc:D93F9F3D2712ED00|rigid:leRLZC3B9Hb5iNvYsNad50kliM0 false myc tag:?-? - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q90922 uniprotkb:Q63155 intact:EBI-1798593 intact:EBI-1798965 psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1798987|imex:IM-12061-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 go:"GO:0005102"(signaling receptor binding) - - figure legend:Fig. 3A|caution:The methods and materials describe Netrin-1 as a myc construct, the text as an Fc construct. This has been annotated as a myc-construct as there is no description elsewhere of the protein as an Fc construct.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:1BC399CDA84C6F98|rigid:u3NLLsijzjKCbkD6dHjV2Li5few false myc tag:c-c - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9ERC8 uniprotkb:Q90922 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0440"(saturation binding) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799003|imex:IM-12061-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) go:"GO:0005102"(signaling receptor binding) - - figure legend:Fig. 3F|caution:The methods and materials describe the experiment as being conducted in Cos-1 cells, the figure legend as 293 cells. Entry has been annotated to Cos-1 cells as these have been used throughout the remainder of the paper. The exact coordinates of the netrin-1 VI-V fragment could not be determined.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:B3509D90038ED544|rigid:leRLZC3B9Hb5iNvYsNad50kliM0 false - fusion protein:?-?|sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VHZ8 uniprotkb:Q63155 intact:EBI-1799020 intact:EBI-1798965 psi-mi:dscam_rat(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1799040|imex:IM-12061-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013106(Immunoglobulin V-set)|rgd:619992|refseq:NP_598271.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|reactome:R-RNO-376172|interpro:IPR043204|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 go:"GO:0030424"(axon) - - figure legend:Fig. 5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-spinal-cord)|taxid:10116(Rattus norvegicus spinal cord) - 2008/08/05 2014/10/16 rogid:PcL3DOyJttzH6dICMnCVoX0v5M010116 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:69C99B51B1054C58|rigid:7ESTQA0lQUjroIKFFDoCEZyhZ+4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q63155 uniprotkb:Q9ERC8 intact:EBI-1798965 intact:EBI-1798601|ensembl:ENSMUSP00000056040 psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1798663|imex:IM-12061-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C, 5E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 intact-crc:7CADA4886239E5C4|rigid:yGi8/hvMbFZEIO9gvxvyFZFeJtM false ha tag:?-? myc tag:?-?|necessary binding region:1595-1615 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERC8 uniprotkb:Q90922 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1798743|imex:IM-12061-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3D|caution:"The Dscam construct was described by the author as \"an in vitro-translated dominant-negative (DN) form of DSCAM (lacking the cytoplasmic domain)\" - it is unclear if this is an exact match to the ecto domain construct described in this interaction."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:C95F9220CD0C30DA|rigid:leRLZC3B9Hb5iNvYsNad50kliM0 false ha tag:?-?|sufficient binding region:1-1594|35s radiolabel:?-? myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERC8 uniprotkb:Q63155 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798965 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799079|imex:IM-12061-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 psi-mi:"MI:0469"(intact) - - figure legend:Figs. 5C, 5E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:B41683B8F347DB59|rigid:yGi8/hvMbFZEIO9gvxvyFZFeJtM false myc tag:?-?|necessary binding region:1595-1615 ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERC8 uniprotkb:Q90922 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799133|imex:IM-12061-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:6FA8500C43AD049D|rigid:ekWjwkntWH8bWqFNfmW+9pJ3U9s false myc tag:?-? myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERC8 uniprotkb:Q63155 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798965 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799133|imex:IM-12061-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:6FA8500C43AD049D|rigid:ekWjwkntWH8bWqFNfmW+9pJ3U9s false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERC8 uniprotkb:Q63155 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798965 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799148|imex:IM-12061-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:FCCF3C5B6EEBFD0A|rigid:ekWjwkntWH8bWqFNfmW+9pJ3U9s false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERC8 uniprotkb:Q90922 intact:EBI-1798601|ensembl:ENSMUSP00000056040 intact:EBI-1798593 psi-mi:dscam_mouse(display_long)|uniprotkb:Dscam(gene name)|psi-mi:Dscam(display_short) psi-mi:net1_chick(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799148|imex:IM-12061-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112451.1|ensembl:ENSMUSG00000050272(gene)|ensembl:ENSMUST00000056102(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010842"(retina layer formation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033027|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-MMU-376172|interpro:IPR013106(Immunoglobulin V-set) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold)|refseq:NP_990750.1|interpro:IPR008979(Galactose-binding like)|rcsb pdb:4PLM|rcsb pdb:4PLN|rcsb pdb:4PLO|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042100"(B cell proliferation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0071944"(cell periphery)|go:"GO:2000147"(positive regulation of cell motility) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:F74WFvqir5+tLwnp/1ypg0GA0Os10090 rogid:x47DND1+c84qhxIh8nZ1iJG8MVw9031 intact-crc:FCCF3C5B6EEBFD0A|rigid:ekWjwkntWH8bWqFNfmW+9pJ3U9s false myc tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63155 uniprotkb:Q63155 intact:EBI-1798965 intact:EBI-1798965 psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799206|imex:IM-12061-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:6290B3CECAE4388C|rigid:rlfQJyd9hJLZ+C6Bvwrs0XkU8Yk false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q63155 uniprotkb:Q63155 intact:EBI-1798965 intact:EBI-1798965 psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:dcc_rat(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ly et al. (2008) imex:IM-12061|pubmed:18585357 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1799215|imex:IM-12061-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 rgd:2492|refseq:NP_036973.1|dip:DIP-46811N|reactome:R-RNO-373752|reactome:R-RNO-418885|reactome:R-RNO-418889|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3LAF|rcsb pdb:3O71|rcsb pdb:5Z5K|rcsb pdb:6BZ3 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/08/05 2014/10/16 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 rogid:f9bBlRhCIGay3wVNWUCZ46hmyb010116 intact-crc:497A3944AE56BE5A|rigid:rlfQJyd9hJLZ+C6Bvwrs0XkU8Yk false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)