#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7ZVP2 uniprotkb:B2XCL9 intact:EBI-1776526|ensembl:ENSDARP00000033828|ensembl:ENSDARP00000156922 intact:EBI-1778249 psi-mi:q7zvp2_danre(display_long)|uniprotkb:rab5c(gene name)|psi-mi:rab5c(display_short) psi-mi:b2xcl9_danre(display_long)|uniprotkb:appl1(gene name)|psi-mi:appl1(display_short) psi-mi:"MI:0096"(pull down) Schenck et al. (2008) imex:IM-11958|pubmed:18455989 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1776539|imex:IM-11958-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_958909.1|ensembl:ENSDARG00000026712(gene)|ensembl:ENSDART00000034536(transcript)|ensembl:ENSDART00000191833(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DRE-432722|reactome:R-DRE-6798695|reactome:R-DRE-8854214|reactome:R-DRE-8856828|reactome:R-DRE-8873719|reactome:R-DRE-8876198 interpro:IPR027267|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_001121546.1|interpro:IPR037929|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007049"(cell cycle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045335"(phagocytic vesicle) psi-mi:"MI:0469"(intact) - - figure legend:1 D, S5|author-identifiers:EBI-1778249 gene EU053152|stimulant:This interaction was stimulated when RAB5C was preloaded with GTP as compared to GDP.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/05/22 2014/10/16 rogid:76feGnK6irF53g+aoFUR7BGnjr87955 rogid:pRDOK6gmdR/npsV725cVNH9JMzQ7955 intact-crc:BD7A4CB33BAAB31E|rigid:tDlMnmd2ykVHWGDS4lV49D6/G6M false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:B2XCM0 uniprotkb:Q7ZVP2 intact:EBI-1778258 intact:EBI-1776526|ensembl:ENSDARP00000033828|ensembl:ENSDARP00000156922 psi-mi:b2xcm0_danre(display_long)|uniprotkb:appl2(gene name)|psi-mi:appl2(display_short) psi-mi:q7zvp2_danre(display_long)|uniprotkb:rab5c(gene name)|psi-mi:rab5c(display_short) psi-mi:"MI:0096"(pull down) Schenck et al. (2008) imex:IM-11958|pubmed:18455989 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1778288|imex:IM-11958-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_001121547.1|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0007049"(cell cycle)|go:"GO:0010008"(endosome membrane)|go:"GO:0023052"(signaling)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045335"(phagocytic vesicle) refseq:NP_958909.1|ensembl:ENSDARG00000026712(gene)|ensembl:ENSDART00000034536(transcript)|ensembl:ENSDART00000191833(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DRE-432722|reactome:R-DRE-6798695|reactome:R-DRE-8854214|reactome:R-DRE-8856828|reactome:R-DRE-8873719|reactome:R-DRE-8876198 psi-mi:"MI:0469"(intact) - - figure legend:1 D|author-identifiers:EBI-1778258 gene EU053153|stimulant:This interaction was stimulated when RAB5C was preloaded with GTP as compared to GDP.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/05/22 2014/10/16 rogid:qQ2lKNXauqKOuZGQdnWO8Z9zBkI7955 rogid:76feGnK6irF53g+aoFUR7BGnjr87955 intact-crc:0EBD4F983BD3951E|rigid:cm+PR8DP1OYkYbMVK3ZBZ87WdmQ false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q7ZVP2 uniprotkb:B2XCL9 intact:EBI-1776526|ensembl:ENSDARP00000033828|ensembl:ENSDARP00000156922 intact:EBI-1778249 psi-mi:q7zvp2_danre(display_long)|uniprotkb:rab5c(gene name)|psi-mi:rab5c(display_short) psi-mi:b2xcl9_danre(display_long)|uniprotkb:appl1(gene name)|psi-mi:appl1(display_short) psi-mi:"MI:0663"(confocal microscopy) Schenck et al. (2008) imex:IM-11958|pubmed:18455989 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1778135|imex:IM-11958-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_958909.1|ensembl:ENSDARG00000026712(gene)|ensembl:ENSDART00000034536(transcript)|ensembl:ENSDART00000191833(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DRE-432722|reactome:R-DRE-6798695|reactome:R-DRE-8854214|reactome:R-DRE-8856828|reactome:R-DRE-8873719|reactome:R-DRE-8876198 interpro:IPR027267|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_001121546.1|interpro:IPR037929|go:"GO:0001726"(ruffle)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007049"(cell cycle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045335"(phagocytic vesicle) psi-mi:"MI:0469"(intact) - - figure legend:1 B, C, S2|delivery method:EBI-1778249; Q7ZVP2 injection|author-identifiers:EBI-1778249 gene EU053152|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-embryo)|taxid:7955(Danio rerio Embryo) - 2008/05/22 2014/10/16 rogid:76feGnK6irF53g+aoFUR7BGnjr87955 rogid:pRDOK6gmdR/npsV725cVNH9JMzQ7955 intact-crc:E3167B343B89B1D3|rigid:tDlMnmd2ykVHWGDS4lV49D6/G6M false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)