#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:15996"	uniprotkb:P37894	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1784742|ensemblbacteria:AAK24453	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:"MI:0415"(enzymatic study)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1784763|imex:IM-11917-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	crc64:DCFF4F092DE2CBF8	figure legend:Fig. 1|comment:The single domain response regulator DivK is able to efficiently stimulate the in vitro activity of PleD and that this activation requires an active histidine protein kinase PleC.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2016/08/15	-	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	intact-crc:4951AE0D8899C968	false	-	mutation decreasing interaction:778-778|sufficient binding region:303-842	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:Q9A5I5	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1784763|imex:IM-11917-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	crc64:D44909D42B581516	figure legend:Fig. 1|comment:The single domain response regulator DivK is able to efficiently stimulate the in vitro activity of PleD and that this activation requires an active histidine protein kinase PleC.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2016/08/15	-	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	intact-crc:4951AE0D8899C968	false	-	mutation decreasing interaction:53-53	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:Q45976	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-1784754	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0415"(enzymatic study)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1784763|imex:IM-11917-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Fig. 1|comment:The single domain response regulator DivK is able to efficiently stimulate the in vitro activity of PleD and that this activation requires an active histidine protein kinase PleC.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2016/08/15	-	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:4951AE0D8899C968	false	-	mutation increasing interaction:53-53	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37894	-	intact:EBI-1784742|ensemblbacteria:AAK24453	-	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	-	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	-	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1784858|imex:IM-11917-9	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 2A|resulting-ptm:Phosphorylation of PleC, Supp. Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	-	intact-crc:0541CED82CAE57E0	false	sufficient binding region:303-842	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1784864|imex:IM-11917-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 2A, 2C, Supp. Fig 1A & B|comment:DivKD53N stimulated levels of PleC autophosphorylation in a concentration dependent manner|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:4BAB886CEABBDBCF|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	sufficient binding region:303-842	mutation:53-53|mutation decreasing interaction:53-53,90-90	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q9A5I5	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1784941|imex:IM-11917-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	go:"GO:0018106"(peptidyl-histidine phosphorylation)|go:"GO:0004673"(protein histidine kinase activity)	crc64:DCFF4F092DE2CBF8	crc64:D44909D42B581516	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	intact-crc:EC4C10FDCD5112E3|rigid:Z1f2AcOYT8KvJLdanXuBxJMPKHs	false	phosphorylated residue:?-?|sufficient binding region:303-842	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q9A5I5	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785024|imex:IM-11917-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:DCFF4F092DE2CBF8	crc64:D44909D42B581516	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	intact-crc:3AA8ED340B3130A0|rigid:52ma+U3Kovdjy2YrYPoa2ZP9Eu0	false	phosphorylated residue:?-?|sufficient binding region:303-842	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785024|imex:IM-11917-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:3AA8ED340B3130A0|rigid:52ma+U3Kovdjy2YrYPoa2ZP9Eu0	false	phosphorylated residue:?-?|sufficient binding region:303-842	mutation:53-53	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785070|imex:IM-11917-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 3A, Supp. Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:CB5D807796868DAC|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	phosphorylated residue:?-?|sufficient binding region:303-842	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785070|imex:IM-11917-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 3A, Supp. Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:CB5D807796868DAC|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	phosphorylated residue:?-?|sufficient binding region:303-842	mutation:53-53	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0841"(phosphotransferase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785084|imex:IM-11917-6	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:9A43E3E4BA1C3A90|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	phosphorylated residue:?-?|sufficient binding region:303-842	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03228	uniprotkb:Q45976	intact:EBI-1785038|ensemblbacteria:AAK23047	intact:EBI-1784754	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785048|imex:IM-11917-4	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:802B532B749B37EA	-	figure legend:Fig. 2D, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:F032A148C1A758A6|rigid:vqqLcHlMGxA186Fc5PSdX1FOOSQ	false	phosphorylated residue:?-?|sufficient binding region:301-597	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9A5I5	uniprotkb:Q03228	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	intact:EBI-1785038|ensemblbacteria:AAK23047	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785057|imex:IM-11917-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:D44909D42B581516	crc64:802B532B749B37EA	figure legend:Fig. 2D, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	intact-crc:B42D421217A73CFF|rigid:qNuvgy+h45QQhKVxWANEKlu3x5M	false	-	phosphorylated residue:?-?|sufficient binding region:301-597	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q45976	uniprotkb:Q03228	intact:EBI-1784754	intact:EBI-1785038|ensemblbacteria:AAK23047	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785133|imex:IM-11917-7	-	-	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	crc64:802B532B749B37EA	figure legend:Fig. 4A, Supp. Fig 1C|comment:A asp53asn, asp90gly mutant of DivK was also included in the assay but the author did not comment on any effect.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	intact-crc:BF135DF8DAA44DB0|rigid:vqqLcHlMGxA186Fc5PSdX1FOOSQ	false	mutation:53-53|mutation decreasing interaction:53-53,90-90	sufficient binding region:301-597	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03228	-	intact:EBI-1785038|ensemblbacteria:AAK23047	-	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	-	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785142|imex:IM-11917-8	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	crc64:802B532B749B37EA	-	figure legend:Fig. 4A, Supp. Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	-	intact-crc:1FA8AF13080760EA	false	sufficient binding region:301-597	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-
uniprotkb:Q03228	uniprotkb:Q45976	intact:EBI-1785038|ensemblbacteria:AAK23047	intact:EBI-1784754	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785149|imex:IM-11917-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:802B532B749B37EA	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:4F82F623BB20CA27|rigid:vqqLcHlMGxA186Fc5PSdX1FOOSQ	false	phosphorylated residue:?-?|sufficient binding region:301-597	mutation:53-53	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03228	uniprotkb:Q45976	intact:EBI-1785038|ensemblbacteria:AAK23047	intact:EBI-1784754	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785149|imex:IM-11917-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:802B532B749B37EA	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:4F82F623BB20CA27|rigid:vqqLcHlMGxA186Fc5PSdX1FOOSQ	false	phosphorylated residue:?-?|sufficient binding region:301-597	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03228	uniprotkb:Q9A5I5	intact:EBI-1785038|ensemblbacteria:AAK23047	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785161|imex:IM-11917-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:802B532B749B37EA	crc64:D44909D42B581516	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	intact-crc:0E0A81F020E767FE|rigid:aSEAhebgHsBL4w4VevI1zUyf2CM	false	phosphorylated residue:?-?|sufficient binding region:301-597	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03228	uniprotkb:Q45976	intact:EBI-1785038|ensemblbacteria:AAK23047	intact:EBI-1784754	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785161|imex:IM-11917-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)	crc64:802B532B749B37EA	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:0E0A81F020E767FE|rigid:aSEAhebgHsBL4w4VevI1zUyf2CM	false	phosphorylated residue:?-?|sufficient binding region:301-597	mutation:53-53	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0434"(phosphatase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785108|imex:IM-11917-14	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:7B85B6ABA49A112E|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	sufficient binding region:303-842	phosphorylated residue:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0434"(phosphatase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785121|imex:IM-11917-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 3B, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:3F00C340E4542377|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	sufficient binding region:303-842	phosphorylated residue:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0434"(phosphatase assay)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785121|imex:IM-11917-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)	crc64:DCFF4F092DE2CBF8	-	figure legend:Fig. 3B, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:3F00C340E4542377|rigid:Hz7INjXYZLDD0l7GjslV9z+MpLg	false	sufficient binding region:303-842	mutation:53-53	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9A5I5	uniprotkb:Q9A5I5	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785217|imex:IM-11917-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	go:"GO:0046983"(protein dimerization activity)	crc64:D44909D42B581516	crc64:D44909D42B581516	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	intact-crc:83EF1C67786DDCA4|rigid:rv0cnxe7oCwZfpUCGKFG26v+pcs	false	-	-	2	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P37894	uniprotkb:Q9A5I5	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784732|uniprotkb:Q46020|ensemblbacteria:AAK24433	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:pled_cauvc(display_long)|uniprotkb:pleD(gene name)|psi-mi:pleD(display_short)|uniprotkb:CC_2462(locus name)|uniprotkb:Stalked cell differentiation-controlling protein(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785222|imex:IM-11917-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:NP_421265.1|refseq:WP_010920320.1|dip:DIP-29503N|ensemblbacteria:AAK24433(transcript)|ensemblbacteria:CC_2462(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052621"(diguanylate cyclase activity)|interpro:IPR000160(GGDEF)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR029787|interpro:IPR043128	go:"GO:0046983"(protein dimerization activity)	crc64:DCFF4F092DE2CBF8	crc64:D44909D42B581516	comment:Whilst there was low level of dimerization of PleD in the ansence of PleC and DivK, the presence of these proteins stimulated dimer formation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:CuhOtZ7rwc3fMbZr9Rkv7Rbkh8g190650	intact-crc:D8E7A330D92F8871|rigid:52ma+U3Kovdjy2YrYPoa2ZP9Eu0	false	sufficient binding region:303-842	-	-	2	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P37894	uniprotkb:Q45976	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784754	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:q45976_cauvi(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)	psi-mi:"MI:0030"(cross-linking study)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:155892(cauce)|taxid:155892(Caulobacter crescentus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785222|imex:IM-11917-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:WP_012640499.1|dip:DIP-46001N|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0051301"(cell division)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)	go:"GO:0046983"(protein dimerization activity)	crc64:DCFF4F092DE2CBF8	-	comment:Whilst there was low level of dimerization of PleD in the ansence of PleC and DivK, the presence of these proteins stimulated dimer formation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:goqbrIIUHgv4N57CFxDu77tiAEY155892	intact-crc:D8E7A330D92F8871|rigid:52ma+U3Kovdjy2YrYPoa2ZP9Eu0	false	sufficient binding region:303-842	mutation:53-53	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P37894	uniprotkb:P37894	intact:EBI-1784742|ensemblbacteria:AAK24453	intact:EBI-1784742|ensemblbacteria:AAK24453	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:plec_cauvc(display_long)|uniprotkb:pleC(gene name)|psi-mi:pleC(display_short)|uniprotkb:CC_2482(locus name)	psi-mi:"MI:0071"(molecular sieving)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785251|imex:IM-11917-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	refseq:NP_421285.1|refseq:WP_010920340.1|dip:DIP-44286N|mint:P37894|ensemblbacteria:AAK24453(transcript)|ensemblbacteria:CC_2482(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890	go:"GO:0042803"(protein homodimerization activity)	crc64:DCFF4F092DE2CBF8	crc64:DCFF4F092DE2CBF8	figure legend:Supp. Fig. 3|comment:The distribution of PleC monomer and dimer fraction was not affected by preincubation with DivK.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	rogid:RducT33chfnanZ2jOBVO0SZZFnU190650	intact-crc:ABEE0FC7EB064421|rigid:URiibCR2K1L4hGcXq/mGVE3Y5Tk	false	sufficient binding region:303-842	sufficient binding region:303-842	2	0	psi-mi:"MI:0815"(confirmation by molecular weight)	psi-mi:"MI:0815"(confirmation by molecular weight)
uniprotkb:Q03228	uniprotkb:Q03228	intact:EBI-1785038|ensemblbacteria:AAK23047	intact:EBI-1785038|ensemblbacteria:AAK23047	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:divj_cauvc(display_long)|uniprotkb:divJ(gene name)|psi-mi:divJ(display_short)|uniprotkb:CC_1063(locus name)	psi-mi:"MI:0071"(molecular sieving)	Paul et al. (2008)	imex:IM-11917|pubmed:18455986	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	taxid:190650(caucr)|taxid:190650("Caulobacter crescentus (strain ATCC 19089 / CB15)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1785257|imex:IM-11917-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	refseq:NP_419879.1|dip:DIP-46002N|ensemblbacteria:AAK23047(transcript)|ensemblbacteria:CC_1063(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0051301"(cell division)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890	go:"GO:0042803"(protein homodimerization activity)	crc64:802B532B749B37EA	crc64:802B532B749B37EA	figure legend:Supp. Fig. 4|comment:The DivJ dimer fraction was not affected by preincubation with DivK.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/06/23	2014/10/16	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	rogid:uTM1on1fmewdK62YMdKSKJrzbgA190650	intact-crc:65848359979C78A1|rigid:zCikhwgwbYF1mc2Fmbn5gzKO2Kk	false	sufficient binding region:301-597	sufficient binding region:301-597	2	0	psi-mi:"MI:0815"(confirmation by molecular weight)	psi-mi:"MI:0815"(confirmation by molecular weight)