#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92600	uniprotkb:P50616	intact:EBI-357079|uniprotkb:Q96IX4|uniprotkb:B2RPI0|uniprotkb:B7Z1E5|uniprotkb:B5MDQ4|ensembl:ENSP00000273064|ensembl:ENSP00000443687	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cnot9_human(display_long)|uniprotkb:Cell differentiation protein RQCD1 homolog(gene name synonym)|uniprotkb:RCD1(gene name synonym)|uniprotkb:RQCD1(gene name synonym)|uniprotkb:CNOT9(gene name)|psi-mi:CNOT9(display_short)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2104352|imex:IM-20166-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-46840N|refseq:NP_005435.1|refseq:NP_001258564.1|refseq:NP_001258563.1|ensembl:ENSG00000144580(gene)|ensembl:ENST00000273064(transcript)|ensembl:ENST00000542068(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:2FV2|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:5LSW|rcsb pdb:5ONA|rcsb pdb:5ONB|rcsb pdb:6HOM|rcsb pdb:6HON|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:/oDjYD0axKIkLMKxmji2q+sg+K49606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:CDC87B084BCB18A2|rigid:LyTfKnithHjLvwsVZtQs2rA7DWQ	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:Q9NZN8	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105090|imex:IM-20166-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606	intact-crc:66692FE5CDCA1FBE|rigid:n7t62cJzdq13ckELHBJt7zoTpVg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:O75175	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105099|imex:IM-20166-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606	intact-crc:BB75DEB4BED9CCA4|rigid:qMOeA4QRMaGcVtVcisOF/bOAl9A	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:Q96LI5	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105106|imex:IM-20166-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:2Y605zw41TOo2ATkUM/7ToUb6449606	intact-crc:F783DCC1CEA91C9D|rigid:3CFS9gUcMqnzpf9QeLz7A7AjgKg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9UIV1	uniprotkb:P50616	intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105132|imex:IM-20166-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:D00640B308FC237B|rigid:EkXAqRumbK3mxOpDS6COXZQaQh4	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:A5YKK6	uniprotkb:P50616	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105140|imex:IM-20166-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:1B9FC4113460C0C5|rigid:lX3/mvRoFk/Biyd8MOSt3T0QkqY	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H9A5	uniprotkb:P50616	intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105146|imex:IM-20166-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:92BjBXGyxALldfF9AVpP+EFN38k9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:51026D8278F64102|rigid:leXlAslBIinj1fKGWSzKnkApkr4	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q8IY67	uniprotkb:P50616	intact:EBI-2105155|uniprotkb:A6NMU4|uniprotkb:Q8IY60|uniprotkb:Q8TF24|intact:EBI-2562007|ensembl:ENSP00000479520	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:ravr1_human(display_long)|uniprotkb:RAVER1(gene name)|psi-mi:RAVER1(display_short)|uniprotkb:KIAA1978(gene name synonym)|uniprotkb:Protein raver-1(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105180|imex:IM-20166-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_597709.2|dip:DIP-46973N|ensembl:ENSG00000161847(gene)|ensembl:ENST00000615032(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3SMZ|rcsb pdb:3VF0	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:bu5ZIcFaIb6EihZAWpUflnrWL1w9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:27DF1837F57F34D9|rigid:fOnxYW6sYM2PIxk5hlMqhDlEvvs	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:Q07666	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105193|imex:IM-20166-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606	intact-crc:497455C2198A35CE|rigid:J2nbQ1fs41yR4znbFjes0AIryrY	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q13148	uniprotkb:P50616	intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105201|imex:IM-20166-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:8BAB1F58C32A7224|rigid:zxS6uhl+FbcsgSG9GyxbKXbzGH0	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:P31483	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105208|imex:IM-20166-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	refseq:NP_071320.2|refseq:NP_071505.2|ensembl:ENSG00000116001(gene)|ensembl:ENST00000433529(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034830|interpro:IPR034832|interpro:IPR035979|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|reactome:R-HSA-6803529|mint:P31483	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	intact-crc:68D9C44C52E2E878|rigid:MKZ842F710T0KImcdcNVOKlcatw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P22626	uniprotkb:P50616	intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105216|imex:IM-20166-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:E531EF8FC97ACE00|rigid:+c9aC7fy32y93rbAmWGOlHnLWyA	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P52597	uniprotkb:P50616	intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105223|imex:IM-20166-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:C48398D3C9E0D2F3|rigid:y/hs7lDLp3PF7t8u2CvJeAucN4c	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:P31943	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105231|imex:IM-20166-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	intact-crc:3A0413F66651BC7F|rigid:IX/SmfpHc46jWvnn1Fq3Q8GOAEw	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:P55795	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105238|imex:IM-20166-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606	intact-crc:2042517DC3BF892C|rigid:sW0DSLJ7e+c4XoFw9Ljxup9Elcs	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P31942	uniprotkb:P50616	intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105245|imex:IM-20166-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:B2AE05E7EFB570EB|rigid:YTUeVu5i7bMRXNB9wk3NmbcPZ6E	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P61978	uniprotkb:P50616	intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105252|imex:IM-20166-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:DD1AF6BAE260AD5D|rigid:km+8Z35dtkW034+yFP/AWvBeFx4	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:O00571	uniprotkb:P50616	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105259|imex:IM-20166-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:DD444AAA3814ECBE|rigid:xGfId5OyLgHJt1VoB1GCpxLLLzM	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:P17844	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105266|imex:IM-20166-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	intact-crc:3EBED991A0DE1B62|rigid:aLDBaZflalv2J95ZbvmXR35iK1k	false	flag tag:?-?	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9C0C2	uniprotkb:P50616	intact:EBI-2104458|uniprotkb:Q6PJ35|uniprotkb:Q6ZV74|uniprotkb:A7E2F8|intact:EBI-28975617|ensembl:ENSP00000350990|ensembl:ENSP00000437271	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:tb182_human(display_long)|uniprotkb:TNKS1BP1(gene name)|psi-mi:TNKS1BP1(display_short)|uniprotkb:KIAA1741(gene name synonym)|uniprotkb:TAB182(gene name synonym)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105295|imex:IM-20166-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006718788.1|ensembl:ENSP00000350990|ensembl:ENSP00000437271|refseq:NP_203754.2|ensembl:ENSG00000149115(gene)|ensembl:ENST00000358252(transcript)|ensembl:ENST00000532437(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|reactome:R-HSA-429947|reactome:R-HSA-6804115	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	go:"GO:0005634"(nucleus)	-	-	figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/11/06	2014/10/16	rogid:pOIaK7wn7iYvUHbSA0kUZlIgtgw9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:62A8CC3B225DFF4B|rigid:ksg2zbJW1lr9An4Y7ogDK2UD1Fs	false	-	flag tag:?-?	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P50616	uniprotkb:O75175	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105309|imex:IM-20166-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N	-	-	-	delivery method:O75175; P50616 transfection|figure legend:3d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2008/11/06	2014/10/16	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606	intact-crc:3B35DBB7B8C4C89A|rigid:qMOeA4QRMaGcVtVcisOF/bOAl9A	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96LI5	uniprotkb:P50616	intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105319|imex:IM-20166-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	-	-	-	delivery method:Q9UF92; P50616 transfection|figure legend:3d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2008/11/06	2014/10/16	rogid:2Y605zw41TOo2ATkUM/7ToUb6449606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:5820FDD5ED8C2A91|rigid:3CFS9gUcMqnzpf9QeLz7A7AjgKg	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5YKK6	uniprotkb:P50616	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105332|imex:IM-20166-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	-	-	-	delivery method:P50616; A5YKK6 transfection|figure legend:3b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2008/11/06	2014/10/16	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:9D0FCFAB378D0621|rigid:lX3/mvRoFk/Biyd8MOSt3T0QkqY	false	flag tag:?-?|binding-associated region:1-1700|binding-associated region:1677-2376	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96LI5	uniprotkb:P50616	intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105344|imex:IM-20166-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	-	-	-	comment:"The interaction supressses the deadenylasae activity of CNOT6L (in vitro)."|delivery method:Q9UF92; P50616 transfection|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/11/06	2014/10/16	rogid:2Y605zw41TOo2ATkUM/7ToUb6449606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:21F7D706611402F4|rigid:3CFS9gUcMqnzpf9QeLz7A7AjgKg	false	green fluorescent protein tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5YKK6	uniprotkb:P50616	intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949	intact:EBI-723281|uniprotkb:Q4KMQ0|intact:EBI-28983166|ensembl:ENSP00000268957|ensembl:ENSP00000427695|uniprotkb:B2R9T0|uniprotkb:D3DTY3	psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name)	psi-mi:tob1_human(display_long)|uniprotkb:Transducer of erbB-2 1(gene name synonym)|uniprotkb:TOB1(gene name)|psi-mi:TOB1(display_short)|uniprotkb:TOB(gene name synonym)|uniprotkb:TROB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Miyasaka et al. (2008)	pubmed:18377426|imex:IM-20166	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2106406|imex:IM-20166-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115	refseq:NP_005740.1|refseq:NP_001230806.1|refseq:NP_001230814.1|go:"GO:0046332"(SMAD binding)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015677(Transducer of ErbB-2, 1)|interpro:IPR036054|mint:P50616|rcsb pdb:2D5R|rcsb pdb:2Z15|rcsb pdb:5CI8|rcsb pdb:5CI9|go:"GO:0045668"(negative regulation of osteoblast differentiation)|ensembl:ENSG00000141232(gene)|ensembl:ENST00000268957(transcript)|ensembl:ENST00000499247(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|ensembl:ENSP00000268957|ensembl:ENSP00000427695	-	-	-	delivery method:P50616; A5YKK6 transfection|figure legend:3c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2008/11/06	2014/10/16	rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606	rogid:kJ3wPXuioip9D7MDuFmxnXTkP9w9606	intact-crc:D023EC7B045B7C45|rigid:lX3/mvRoFk/Biyd8MOSt3T0QkqY	false	-	flag tag:?-?|binding-associated region:114-345	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)