#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12023-2	uniprotkb:P10039	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123356|uniprotkb:O73584|uniprotkb:O73585|uniprotkb:P13132	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:tena_chick(display_long)|uniprotkb:TNC(gene name)|psi-mi:TNC(display_short)|uniprotkb:Tenascin-C(gene name synonym)|uniprotkb:Hexabrachion(gene name synonym)|uniprotkb:Cytotactin(gene name synonym)|uniprotkb:Neuronectin(gene name synonym)|uniprotkb:GMEM(gene name synonym)|uniprotkb:JI(gene name synonym)|uniprotkb:Myotendinous antigen(gene name synonym)|uniprotkb:Glioma-associated-extracellular matrix antigen(gene name synonym)|uniprotkb:GP 150-225(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR000742(EGF-like, type 3)|interpro:IPR013111(EGF, extracellular)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1QR4|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161|interpro:IPR033078|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:IM62AFyOmW2NahbiOwfOeFj0UYY9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:P14781	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123196|uniprotkb:P10450|ensembl:ENSGALP00000038042|ensembl:ENSGALP00000050725	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:cntn1_chick(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Neural cell recognition molecule F11(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	refseq:NP_001004381.3|ensembl:ENSGALG00000009523(gene)|ensembl:ENSGALT00000038834(transcript)|ensembl:ENSGALT00000075780(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:5E53	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:A8ut/kBfKJK0OyJB83ZbpnJL3Sc9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:P13590	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123217|uniprotkb:Q90918|uniprotkb:Q90919	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:ncam1_chick(display_long)|uniprotkb:NCAM1(gene name)|psi-mi:NCAM1(display_short)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|rcsb pdb:1IE5|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0099560"(synaptic membrane adhesion)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:oybxq2ErkDIMqgYfnYuni1couR09031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:O42414	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123275|uniprotkb:Q90924	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:nfasc_chick(display_long)|uniprotkb:NFASC(gene name)|psi-mi:NFASC(display_short)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013151(Immunoglobulin)|interpro:IPR026966|refseq:NP_001004493.1|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|interpro:IPR026965|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030424"(axon)|go:"GO:0042552"(myelination)|go:"GO:0050808"(synapse organization)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:N+hhU1/id8p+AXCEEpyBxyvaOb09031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:Q90XC6	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123349	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:q90xc6_chick(display_long)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR008795(Prominin)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031528"(microvillus membrane)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:fgQPzqawKpoTnozQV/e/sVIiIPI9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	intact:EBI-2123176	intact:EBI-286828|ensembl:ENSMUSP00000005406	-	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:f1nn99_chick(display_short)|psi-mi:EBI-2123176(display_long)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	uniprotkb:F1NN99(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:zGm45NBeVe7HEIHNttZx8ppZ7BE9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:Q90610	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123256	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:neo1_chick(display_long)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR033024|interpro:IPR036116|interpro:IPR036179|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0055072"(iron ion homeostasis)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:gN8eMt36XcXoqYwO5tytnPAV5a89031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:Q03696	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2123326	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:ngca_chick(display_long)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:NP_990484.1|interpro:IPR013151(Immunoglobulin)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0044295"(axonal growth cone)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:0NqW2rxyVMgyj14iAgxWYWGuC4E9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:Q90842	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2028003	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:q90842_chick(display_long)|uniprotkb:FAR-1(gene name)|psi-mi:FAR-1(display_short)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR043204|interpro:IPR036179|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:nCmUVZaK3xH0VZ8u3SWqsysdhus9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P12023-2	uniprotkb:P35331	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2028081	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:nrcam_chick(display_long)|uniprotkb:NgCAM-related cell adhesion molecule(gene name synonym)|uniprotkb:Neuronal surface protein Bravo(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027913|imex:IM-19375-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	refseq:NP_990597.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050839"(cell adhesion molecule binding)	-	-	-	figure legend:Fig. 3|caution:"The participant EBI-2028081(P35331) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2016/11/30	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:ceaQ1ylII2Nlq6OwhGMJVZOknnA9031	intact-crc:4129D72B8952F5C6|rigid:B7GOt8oP7yDpvT2nQknljPKo1sU	false	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8IWV2	uniprotkb:P05067-4	intact:EBI-2028276|uniprotkb:Q8IX14|uniprotkb:Q8TC35|uniprotkb:B2RAX3|ensembl:ENSP00000380602|ensembl:ENSP00000396010|ensembl:ENSP00000413642	intact:EBI-302641|ensembl:ENSP00000345463|intact:EBI-8513344|intact:MINT-150885|intact:EBI-8513450|intact:EBI-8513789|intact:EBI-7458081|intact:EBI-7458225|intact:EBI-8513738|intact:EBI-8513677|intact:EBI-8513407|intact:EBI-7457926	psi-mi:cntn4_human(display_long)|uniprotkb:CNTN4(gene name)|psi-mi:CNTN4(display_short)|uniprotkb:Brain-derived immunoglobulin superfamily protein 2(gene name synonym)	psi-mi:p05067-4(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:PreA4 695(isoform synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028269|imex:IM-19375-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531727.1|refseq:XP_011531728.1|refseq:XP_011531729.1|refseq:XP_011531730.1|refseq:XP_011531731.1|refseq:XP_011531732.1|refseq:NP_001193884.1|refseq:NP_001193885.1|refseq:NP_783200.1|refseq:NP_783302.1|refseq:XP_016861271.1|refseq:XP_016861272.1|refseq:XP_016861273.1|ensembl:ENSG00000144619(gene)|ensembl:ENST00000397461(transcript)|ensembl:ENST00000418658(transcript)|ensembl:ENST00000427331(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-HSA-163125	intact:EBI-77613(a4_human)|ensembl:ENSG00000142192(gene)|ensembl:ENST00000348990(transcript)	-	-	isoform-comment:A major isoform.	figure legend:Fig. 4C|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:bEuIzCrzCxpUO3SU+TBgVQly0aI9606	rogid:g3lIuSzu8RGEONgITBEVFyMpfqk9606	intact-crc:ED3C76A0E09108ED|rigid:XF+FOBRb7/ecaycseQq70BmWB+c	false	fusion protein:c-c|sufficient binding region:1-1000	alkaline phosphatase tag:n-n|sufficient binding region:18-612	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05067-4	uniprotkb:Q9P232	intact:EBI-302641|ensembl:ENSP00000345463|intact:EBI-8513344|intact:MINT-150885|intact:EBI-8513450|intact:EBI-8513789|intact:EBI-7458081|intact:EBI-7458225|intact:EBI-8513738|intact:EBI-8513677|intact:EBI-8513407|intact:EBI-7457926	intact:EBI-2028361|uniprotkb:Q9H039|uniprotkb:B9EK50|ensembl:ENSP00000263665	psi-mi:p05067-4(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:PreA4 695(isoform synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:cntn3_human(display_long)|uniprotkb:CNTN3(gene name)|psi-mi:CNTN3(display_short)|uniprotkb:KIAA1496(gene name synonym)|uniprotkb:PANG(gene name synonym)|uniprotkb:Brain-derived immunoglobulin superfamily protein 1(gene name synonym)|uniprotkb:Plasmacytoma-associated neuronal glycoprotein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028386|imex:IM-19375-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(a4_human)|ensembl:ENSG00000142192(gene)|ensembl:ENST00000348990(transcript)	refseq:NP_065923.1|refseq:XP_005264814.1|refseq:XP_016861996.1|ensembl:ENSG00000113805(gene)|ensembl:ENST00000263665(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0043005"(neuron projection)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1WJ3|reactome:R-HSA-163125	-	isoform-comment:A major isoform.	-	figure legend:Fig. 4B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:g3lIuSzu8RGEONgITBEVFyMpfqk9606	rogid:5VFtEKC/lBDVIGIyazUjoQ6LDa89606	intact-crc:8B4B3512FC317FE9|rigid:uWrsXtieqMQzxislirllL5EY4Tg	false	sufficient binding region:18-612|alkaline phosphatase tag:n-n	fusion protein:c-c|sufficient binding region:1-1002	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51693	uniprotkb:Q9P232	intact:EBI-74648|uniprotkb:O00113|uniprotkb:Q96A92|ensembl:ENSP00000498366	intact:EBI-2028361|uniprotkb:Q9H039|uniprotkb:B9EK50|ensembl:ENSP00000263665	psi-mi:aplp1_human(display_long)|uniprotkb:APLP1(gene name)|psi-mi:APLP1(display_short)|uniprotkb:"Amyloid beta (A4) precursor-like protein 1"(gene name synonym)|uniprotkb:Amyloid-like protein 1(gene name synonym)	psi-mi:cntn3_human(display_long)|uniprotkb:CNTN3(gene name)|psi-mi:CNTN3(display_short)|uniprotkb:KIAA1496(gene name synonym)|uniprotkb:PANG(gene name synonym)|uniprotkb:Brain-derived immunoglobulin superfamily protein 1(gene name synonym)|uniprotkb:Plasmacytoma-associated neuronal glycoprotein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028399|imex:IM-19375-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019978.1|refseq:NP_005157.1|dip:DIP-30846N|ensembl:ENSG00000105290(gene)|ensembl:ENST00000652533(transcript)|go:"GO:0005604"(basement membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0031695"(alpha-2B adrenergic receptor binding)|go:"GO:0031696"(alpha-2C adrenergic receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036669|rcsb pdb:3PMR|rcsb pdb:3Q7G|rcsb pdb:3Q7L|rcsb pdb:3QMK|rcsb pdb:4RD9|rcsb pdb:4RDA|interpro:IPR036454	refseq:NP_065923.1|refseq:XP_005264814.1|refseq:XP_016861996.1|ensembl:ENSG00000113805(gene)|ensembl:ENST00000263665(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0043005"(neuron projection)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1WJ3|reactome:R-HSA-163125	-	-	-	figure legend:Fig. 4D|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:6PKn8miZNOLOS3c4MjZFchs1yaQ9606	rogid:5VFtEKC/lBDVIGIyazUjoQ6LDa89606	intact-crc:81E45AAD82F8B2F6|rigid:Wv6iUhpv7GNOnyh5Vw+SufhzdvU	false	alkaline phosphatase tag:n-n|sufficient binding region:34-567	fusion protein:c-c|sufficient binding region:1-1002	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IWV2	uniprotkb:P51693	intact:EBI-2028276|uniprotkb:Q8IX14|uniprotkb:Q8TC35|uniprotkb:B2RAX3|ensembl:ENSP00000380602|ensembl:ENSP00000396010|ensembl:ENSP00000413642	intact:EBI-74648|uniprotkb:O00113|uniprotkb:Q96A92|ensembl:ENSP00000498366	psi-mi:cntn4_human(display_long)|uniprotkb:CNTN4(gene name)|psi-mi:CNTN4(display_short)|uniprotkb:Brain-derived immunoglobulin superfamily protein 2(gene name synonym)	psi-mi:aplp1_human(display_long)|uniprotkb:APLP1(gene name)|psi-mi:APLP1(display_short)|uniprotkb:"Amyloid beta (A4) precursor-like protein 1"(gene name synonym)|uniprotkb:Amyloid-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028601|imex:IM-19375-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531727.1|refseq:XP_011531728.1|refseq:XP_011531729.1|refseq:XP_011531730.1|refseq:XP_011531731.1|refseq:XP_011531732.1|refseq:NP_001193884.1|refseq:NP_001193885.1|refseq:NP_783200.1|refseq:NP_783302.1|refseq:XP_016861271.1|refseq:XP_016861272.1|refseq:XP_016861273.1|ensembl:ENSG00000144619(gene)|ensembl:ENST00000397461(transcript)|ensembl:ENST00000418658(transcript)|ensembl:ENST00000427331(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-HSA-163125	refseq:NP_001019978.1|refseq:NP_005157.1|dip:DIP-30846N|ensembl:ENSG00000105290(gene)|ensembl:ENST00000652533(transcript)|go:"GO:0005604"(basement membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0031695"(alpha-2B adrenergic receptor binding)|go:"GO:0031696"(alpha-2C adrenergic receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036669|rcsb pdb:3PMR|rcsb pdb:3Q7G|rcsb pdb:3Q7L|rcsb pdb:3QMK|rcsb pdb:4RD9|rcsb pdb:4RDA|interpro:IPR036454	-	-	-	figure legend:Fig. 4E|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:bEuIzCrzCxpUO3SU+TBgVQly0aI9606	rogid:6PKn8miZNOLOS3c4MjZFchs1yaQ9606	intact-crc:B3182251C1C63EC1|rigid:LnwzqEFfk8v5l5Ita0U+IkDDuC8	false	fusion protein:c-c|sufficient binding region:1-1000	alkaline phosphatase tag:n-n|sufficient binding region:34-567	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94779	uniprotkb:P51693	intact:EBI-2028625|uniprotkb:O94780|uniprotkb:A1L4P0|uniprotkb:B7ZM07|uniprotkb:E9PKE8|uniprotkb:Q49AF3|ensembl:ENSP00000435637|ensembl:ENSP00000436185	intact:EBI-74648|uniprotkb:O00113|uniprotkb:Q96A92|ensembl:ENSP00000498366	psi-mi:cntn5_human(display_long)|uniprotkb:CNTN5(gene name)|psi-mi:CNTN5(display_short)|uniprotkb:Neural recognition molecule NB-2(gene name synonym)	psi-mi:aplp1_human(display_long)|uniprotkb:APLP1(gene name)|psi-mi:APLP1(display_short)|uniprotkb:"Amyloid beta (A4) precursor-like protein 1"(gene name synonym)|uniprotkb:Amyloid-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028657|imex:IM-19375-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230199.1|refseq:NP_055176.1|refseq:NP_780775.1|refseq:XP_011541173.1|refseq:NP_001230200.1|refseq:XP_016873415.1|ensembl:ENSG00000149972(gene)|ensembl:ENST00000524871(transcript)|ensembl:ENST00000528682(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099054"(presynapse assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032989|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4N68|rcsb pdb:5E52|reactome:R-HSA-163125	refseq:NP_001019978.1|refseq:NP_005157.1|dip:DIP-30846N|ensembl:ENSG00000105290(gene)|ensembl:ENST00000652533(transcript)|go:"GO:0005604"(basement membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0031695"(alpha-2B adrenergic receptor binding)|go:"GO:0031696"(alpha-2C adrenergic receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036669|rcsb pdb:3PMR|rcsb pdb:3Q7G|rcsb pdb:3Q7L|rcsb pdb:3QMK|rcsb pdb:4RD9|rcsb pdb:4RDA|interpro:IPR036454	-	-	-	figure legend:Fig. 4F|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:0URR3jPnx/Uou4z6EIe2SLTMBMc9606	rogid:6PKn8miZNOLOS3c4MjZFchs1yaQ9606	intact-crc:D259FC816A9E4F2A|rigid:erqKy2zPOrmpilC+ZBeKUgHvLC0	false	fusion protein:c-c|sufficient binding region:1-1072	alkaline phosphatase tag:n-n|sufficient binding region:34-567	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P232	uniprotkb:P12023-2	intact:EBI-2028361|uniprotkb:Q9H039|uniprotkb:B9EK50|ensembl:ENSP00000263665	intact:EBI-286828|ensembl:ENSMUSP00000005406	psi-mi:cntn3_human(display_long)|uniprotkb:CNTN3(gene name)|psi-mi:CNTN3(display_short)|uniprotkb:KIAA1496(gene name synonym)|uniprotkb:PANG(gene name synonym)|uniprotkb:Brain-derived immunoglobulin superfamily protein 1(gene name synonym)|uniprotkb:Plasmacytoma-associated neuronal glycoprotein(gene name synonym)	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028736|imex:IM-19375-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065923.1|refseq:XP_005264814.1|refseq:XP_016861996.1|ensembl:ENSG00000113805(gene)|ensembl:ENST00000263665(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0043005"(neuron projection)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1WJ3|reactome:R-HSA-163125	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	-	-	-	figure legend:Fig. 5A|caution:Exact coordinates of FN domain of Q9P232 could not be traced so inferred from UniProtKB record.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:5VFtEKC/lBDVIGIyazUjoQ6LDa89606	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	intact-crc:D72873F13DE90A35|rigid:WbsSv+B2VyOwjEpsS2uGBkCnhWs	false	fusion protein:c-c|sufficient binding region:598..598-992..992(IPR003961)	alkaline phosphatase tag:n-n|sufficient binding region:18-205	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IWV2	uniprotkb:P12023-2	intact:EBI-2028276|uniprotkb:Q8IX14|uniprotkb:Q8TC35|uniprotkb:B2RAX3|ensembl:ENSP00000380602|ensembl:ENSP00000396010|ensembl:ENSP00000413642	intact:EBI-286828|ensembl:ENSMUSP00000005406	psi-mi:cntn4_human(display_long)|uniprotkb:CNTN4(gene name)|psi-mi:CNTN4(display_short)|uniprotkb:Brain-derived immunoglobulin superfamily protein 2(gene name synonym)	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2028999|imex:IM-19375-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531727.1|refseq:XP_011531728.1|refseq:XP_011531729.1|refseq:XP_011531730.1|refseq:XP_011531731.1|refseq:XP_011531732.1|refseq:NP_001193884.1|refseq:NP_001193885.1|refseq:NP_783200.1|refseq:NP_783302.1|refseq:XP_016861271.1|refseq:XP_016861272.1|refseq:XP_016861273.1|ensembl:ENSG00000144619(gene)|ensembl:ENST00000397461(transcript)|ensembl:ENST00000418658(transcript)|ensembl:ENST00000427331(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-HSA-163125	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	-	-	-	figure legend:Fig. 5A|caution:Exact coordinates of FN domain of Q8IWV2 could not be traced so inferred from UniProtKB record.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/05	2014/10/16	rogid:bEuIzCrzCxpUO3SU+TBgVQly0aI9606	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	intact-crc:F106024FA87C9268|rigid:bGcUAhs7QIpdiDzUXAQ53RezH2M	false	fusion protein:c-c|sufficient binding region:596..596-990..990(IPR003961)	alkaline phosphatase tag:n-n|sufficient binding region:18-205	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12023-2	uniprotkb:P35331	intact:EBI-286828|ensembl:ENSMUSP00000005406	intact:EBI-2028081	psi-mi:p12023-2(display_long)|uniprotkb:App(gene name)|psi-mi:App(display_short)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:Amyloidogenic glycoprotein(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)	psi-mi:nrcam_chick(display_long)|uniprotkb:NgCAM-related cell adhesion molecule(gene name synonym)|uniprotkb:Neuronal surface protein Bravo(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Osterfield et al. (2008)	pubmed:18272596|imex:IM-19375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2030238|imex:IM-19375-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78814(a4_mouse)|ensembl:ENSMUSG00000022892(gene)|ensembl:ENSMUST00000005406(transcript)	refseq:NP_990597.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050839"(cell adhesion molecule binding)	-	-	-	figure legend:Fig. 5B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-embryonic_brain)|taxid:9031(Chick embryonic brain)	-	2008/11/05	2014/10/16	rogid:G8f2dDnYndrPDuWyfiwqIScljL410090	rogid:ceaQ1ylII2Nlq6OwhGMJVZOknnA9031	intact-crc:FFEB0D6F6027381B|rigid:7AB0ei21K/1e43i4G8h6UULTVzg	false	alkaline phosphatase tag:n-n|sufficient binding region:199-315	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)