#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60218	uniprotkb:Q13085	intact:EBI-1572139|ensembl:ENSP00000352584|uniprotkb:O75890|uniprotkb:Q6FHF3|uniprotkb:A4D1P1|uniprotkb:Q8IWZ1	intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674	psi-mi:ak1ba_human(display_long)|uniprotkb:Aldose reductase-like(gene name synonym)|uniprotkb:ARL-1(gene name synonym)|uniprotkb:Aldose reductase-related protein(gene name synonym)|uniprotkb:Small intestine reductase(gene name synonym)|uniprotkb:AKR1B10(gene name)|psi-mi:AKR1B10(display_short)|uniprotkb:AKR1B11(gene name synonym)	psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ma et al. (2007)	pubmed:18056116|imex:IM-19787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1572157|imex:IM-19787-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4WEV|rcsb pdb:4XZL|rcsb pdb:4XZM|rcsb pdb:4XZN|rcsb pdb:5LIK|rcsb pdb:5LIU|rcsb pdb:5LIW|rcsb pdb:5LIX|rcsb pdb:5LIY|rcsb pdb:5M2F|rcsb pdb:5Y7N|reactome:R-HSA-975634|ensembl:ENST00000359579(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0016488"(farnesol catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045550"(geranylgeranyl reductase activity)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1ZUA|rcsb pdb:4GA8|rcsb pdb:4GAB|rcsb pdb:4GQ0|rcsb pdb:4GQG|rcsb pdb:4I5X|rcsb pdb:4ICC|ensembl:ENSG00000198074(gene)|rcsb pdb:4JIH|rcsb pdb:4JII|refseq:NP_064695.3	refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N	omim:114480(primary-reference)	-	-	figure legend:Fig. 3 A, B and Fig. 4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rao_3)|taxid:9606(Homo sapiens mammary epithelial cancer cell line RAO-3)	-	2008/01/07	2014/10/16	rogid:u3ZlKjOlmfvDQ6lfAGo/bu11AKA9606	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	intact-crc:F49004B80063D30E|rigid:8ZWFHxoZJI8S2DedgJso8D55aQE	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q13085	uniprotkb:O60218	intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674	intact:EBI-1572139|ensembl:ENSP00000352584|uniprotkb:O75890|uniprotkb:Q6FHF3|uniprotkb:A4D1P1|uniprotkb:Q8IWZ1	psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:ak1ba_human(display_long)|uniprotkb:Aldose reductase-like(gene name synonym)|uniprotkb:ARL-1(gene name synonym)|uniprotkb:Aldose reductase-related protein(gene name synonym)|uniprotkb:Small intestine reductase(gene name synonym)|uniprotkb:AKR1B10(gene name)|psi-mi:AKR1B10(display_short)|uniprotkb:AKR1B11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ma et al. (2007)	pubmed:18056116|imex:IM-19787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1573326|imex:IM-19787-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N	rcsb pdb:4WEV|rcsb pdb:4XZL|rcsb pdb:4XZM|rcsb pdb:4XZN|rcsb pdb:5LIK|rcsb pdb:5LIU|rcsb pdb:5LIW|rcsb pdb:5LIX|rcsb pdb:5LIY|rcsb pdb:5M2F|rcsb pdb:5Y7N|reactome:R-HSA-975634|ensembl:ENST00000359579(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0016488"(farnesol catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045550"(geranylgeranyl reductase activity)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1ZUA|rcsb pdb:4GA8|rcsb pdb:4GAB|rcsb pdb:4GQ0|rcsb pdb:4GQG|rcsb pdb:4I5X|rcsb pdb:4ICC|ensembl:ENSG00000198074(gene)|rcsb pdb:4JIH|rcsb pdb:4JII|refseq:NP_064695.3	omim:114480(primary-reference)	-	-	figure legend:Fig. 5|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rao_3)|taxid:9606(Homo sapiens mammary epithelial cancer cell line RAO-3)	-	2008/01/07	2014/10/16	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	rogid:u3ZlKjOlmfvDQ6lfAGo/bu11AKA9606	intact-crc:9697267A90ABC7ED|rigid:8ZWFHxoZJI8S2DedgJso8D55aQE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60218	uniprotkb:Q13085	intact:EBI-1572139|ensembl:ENSP00000352584|uniprotkb:O75890|uniprotkb:Q6FHF3|uniprotkb:A4D1P1|uniprotkb:Q8IWZ1	intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674	psi-mi:ak1ba_human(display_long)|uniprotkb:Aldose reductase-like(gene name synonym)|uniprotkb:ARL-1(gene name synonym)|uniprotkb:Aldose reductase-related protein(gene name synonym)|uniprotkb:Small intestine reductase(gene name synonym)|uniprotkb:AKR1B10(gene name)|psi-mi:AKR1B10(display_short)|uniprotkb:AKR1B11(gene name synonym)	psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ma et al. (2007)	pubmed:18056116|imex:IM-19787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1573345|imex:IM-19787-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4WEV|rcsb pdb:4XZL|rcsb pdb:4XZM|rcsb pdb:4XZN|rcsb pdb:5LIK|rcsb pdb:5LIU|rcsb pdb:5LIW|rcsb pdb:5LIX|rcsb pdb:5LIY|rcsb pdb:5M2F|rcsb pdb:5Y7N|reactome:R-HSA-975634|ensembl:ENST00000359579(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0016488"(farnesol catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045550"(geranylgeranyl reductase activity)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1ZUA|rcsb pdb:4GA8|rcsb pdb:4GAB|rcsb pdb:4GQ0|rcsb pdb:4GQG|rcsb pdb:4I5X|rcsb pdb:4ICC|ensembl:ENSG00000198074(gene)|rcsb pdb:4JIH|rcsb pdb:4JII|refseq:NP_064695.3	refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N	omim:114480(primary-reference)	-	-	figure legend:5 B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/07	2014/10/16	rogid:u3ZlKjOlmfvDQ6lfAGo/bu11AKA9606	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	intact-crc:CCFFD2CBDDCC91F2|rigid:8ZWFHxoZJI8S2DedgJso8D55aQE	false	his tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13085	uniprotkb:O60218	intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674	intact:EBI-1572139|ensembl:ENSP00000352584|uniprotkb:O75890|uniprotkb:Q6FHF3|uniprotkb:A4D1P1|uniprotkb:Q8IWZ1	psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym)	psi-mi:ak1ba_human(display_long)|uniprotkb:Aldose reductase-like(gene name synonym)|uniprotkb:ARL-1(gene name synonym)|uniprotkb:Aldose reductase-related protein(gene name synonym)|uniprotkb:Small intestine reductase(gene name synonym)|uniprotkb:AKR1B10(gene name)|psi-mi:AKR1B10(display_short)|uniprotkb:AKR1B11(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Ma et al. (2007)	pubmed:18056116|imex:IM-19787	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1573377|imex:IM-19787-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N	rcsb pdb:4WEV|rcsb pdb:4XZL|rcsb pdb:4XZM|rcsb pdb:4XZN|rcsb pdb:5LIK|rcsb pdb:5LIU|rcsb pdb:5LIW|rcsb pdb:5LIX|rcsb pdb:5LIY|rcsb pdb:5M2F|rcsb pdb:5Y7N|reactome:R-HSA-975634|ensembl:ENST00000359579(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0016488"(farnesol catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045550"(geranylgeranyl reductase activity)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1ZUA|rcsb pdb:4GA8|rcsb pdb:4GAB|rcsb pdb:4GQ0|rcsb pdb:4GQG|rcsb pdb:4I5X|rcsb pdb:4ICC|ensembl:ENSG00000198074(gene)|rcsb pdb:4JIH|rcsb pdb:4JII|refseq:NP_064695.3	go:"GO:0005737"(cytoplasm)|omim:114480(primary-reference)	-	-	figure legend:Fig. 6|delivery method:O60218 transfection|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rao_3)|taxid:9606(Homo sapiens mammary epithelial cancer cell line RAO-3)	-	2008/01/07	2014/10/16	rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606	rogid:u3ZlKjOlmfvDQ6lfAGo/bu11AKA9606	intact-crc:F3449B44C96EB9C4|rigid:8ZWFHxoZJI8S2DedgJso8D55aQE	false	-	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)