#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16474 uniprotkb:P53324 intact:EBI-7876|ensemblfungi:YJL034W|uniprotkb:D6VWE9 intact:EBI-23602|uniprotkb:D6VV42|ensemblfungi:YGR263C psi-mi:bip_yeast(display_long)|uniprotkb:KAR2(gene name)|psi-mi:KAR2(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:YJL034W(locus name)|uniprotkb:J1248(orf name)|uniprotkb:Immunoglobulin heavy chain-binding protein homolog(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein homolog(gene name synonym) psi-mi:say1_yeast(display_long)|uniprotkb:SAY1(gene name)|psi-mi:SAY1(display_short)|uniprotkb:YGR263C(locus name) psi-mi:"MI:0416"(fluorescence microscopy) Tiwari et al. (2007) pubmed:18034159|imex:IM-11519|mint:MINT-6179239 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7697771|mint:MINT-6179246|imex:IM-11519-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003571|ensemblfungi:YJL034W(gene)|ensemblfungi:YJL034W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|refseq:NP_012500.3|mint:P16474|dip:DIP-2392N|rcsb pdb:3QFP|rcsb pdb:3QFU|rcsb pdb:3QML|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034099"(luminal surveillance complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:3H0X|mint:MINT-6179249(identity) refseq:NP_011779.3|sgd:S000003495|dip:DIP-5103N|mint:P53324|ensemblfungi:YGR263C(gene)|ensemblfungi:YGR263C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034084"(steryl deacetylase activity)|go:"GO:0034210"(sterol deacetylation)|go:"GO:0071944"(cell periphery)|interpro:IPR019436|interpro:IPR029058|mint:MINT-6179248(identity) go:"GO:0005783"(endoplasmic reticulum) crc64:A107BD03DF3F30D3 crc64:EB0D1D6078CD6516 figure legend:f3f|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/02/13 2014/10/16 rogid:+zA2eFylZ+4FgQ5zac8xx/GRV7g559292 rogid:+fIQb4Lo1yoaik8zQSwSFS01qXA559292 intact-crc:638188CAA46D76E9|rigid:zNBFcRO/efp8mqeYYq/ghlVWXXU false tag:?-?(MINT-6179252) green fluorescent protein tag:?-?(MINT-6179256) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53324 uniprotkb:P32915 intact:EBI-23602|uniprotkb:D6VV42|ensemblfungi:YGR263C intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 psi-mi:say1_yeast(display_long)|uniprotkb:SAY1(gene name)|psi-mi:SAY1(display_short)|uniprotkb:YGR263C(locus name) psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Tiwari et al. (2007) pubmed:18034159|imex:IM-11519|mint:MINT-6179239 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7697821|mint:MINT-6179260|imex:IM-11519-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011779.3|sgd:S000003495|dip:DIP-5103N|mint:P53324|ensemblfungi:YGR263C(gene)|ensemblfungi:YGR263C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034084"(steryl deacetylase activity)|go:"GO:0034210"(sterol deacetylation)|go:"GO:0071944"(cell periphery)|interpro:IPR019436|interpro:IPR029058|mint:MINT-6179267(identity) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915|mint:MINT-6179263(identity) go:"GO:0005783"(endoplasmic reticulum) crc64:EB0D1D6078CD6516 - figure legend:f3f|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/02/13 2014/10/16 rogid:+fIQb4Lo1yoaik8zQSwSFS01qXA559292 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 intact-crc:4CE87EAD108F7DCB|rigid:yWFe5IUq+EGVq9Pp1FMYYiSOeuM false myc tag:?-?(MINT-6179268) - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53324 uniprotkb:P16474 intact:EBI-23602|uniprotkb:D6VV42|ensemblfungi:YGR263C intact:EBI-7876|ensemblfungi:YJL034W|uniprotkb:D6VWE9 psi-mi:say1_yeast(display_long)|uniprotkb:SAY1(gene name)|psi-mi:SAY1(display_short)|uniprotkb:YGR263C(locus name) psi-mi:bip_yeast(display_long)|uniprotkb:KAR2(gene name)|psi-mi:KAR2(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:YJL034W(locus name)|uniprotkb:J1248(orf name)|uniprotkb:Immunoglobulin heavy chain-binding protein homolog(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein homolog(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Tiwari et al. (2007) pubmed:18034159|imex:IM-11519|mint:MINT-6179239 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7697859|mint:MINT-6179293|imex:IM-11519-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011779.3|sgd:S000003495|dip:DIP-5103N|mint:P53324|ensemblfungi:YGR263C(gene)|ensemblfungi:YGR263C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034084"(steryl deacetylase activity)|go:"GO:0034210"(sterol deacetylation)|go:"GO:0071944"(cell periphery)|interpro:IPR019436|interpro:IPR029058|mint:MINT-6179300(identity) sgd:S000003571|ensemblfungi:YJL034W(gene)|ensemblfungi:YJL034W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|refseq:NP_012500.3|mint:P16474|dip:DIP-2392N|rcsb pdb:3QFP|rcsb pdb:3QFU|rcsb pdb:3QML|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034099"(luminal surveillance complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:3H0X|mint:MINT-6179296(identity) go:"GO:0005783"(endoplasmic reticulum) crc64:EB0D1D6078CD6516 crc64:A107BD03DF3F30D3 figure legend:f3g|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/02/13 2014/10/16 rogid:+fIQb4Lo1yoaik8zQSwSFS01qXA559292 rogid:+zA2eFylZ+4FgQ5zac8xx/GRV7g559292 intact-crc:30083F2AC1E2BCA1|rigid:zNBFcRO/efp8mqeYYq/ghlVWXXU false myc tag:?-?(MINT-6179301) - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0113"(western blot)