#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8WVM7 uniprotkb:P54274 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667440|mint:MINT-6178091|imex:IM-11512-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178093(identity) refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N|mint:MINT-6178096(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela 2.11)|taxid:9606(Homo sapiens) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606 intact-crc:C9C3317E01429324|rigid:RNUnbz2KS6hKbqoW7z9RsB2qMT4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:O60216 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667440|mint:MINT-6178091|imex:IM-11512-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178093(identity) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N|mint:MINT-6178094(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela 2.11)|taxid:9606(Homo sapiens) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:C9C3317E01429324|rigid:RNUnbz2KS6hKbqoW7z9RsB2qMT4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q9UQE7 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667440|mint:MINT-6178091|imex:IM-11512-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178093(identity) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N|mint:MINT-6178095(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela 2.11)|taxid:9606(Homo sapiens) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:C9C3317E01429324|rigid:RNUnbz2KS6hKbqoW7z9RsB2qMT4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3U4 uniprotkb:O60216 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667475|mint:MINT-6178106|imex:IM-11512-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N|mint:MINT-6178112(identity) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N|mint:MINT-6178108(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela 2.11)|taxid:9606(Homo sapiens) - 2008/02/12 2014/10/16 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:9FB80A28F214B026|rigid:6SE9ipjIIQGrtHTyhdSNO9KjoKc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3U4 uniprotkb:Q9UQE7 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667475|mint:MINT-6178106|imex:IM-11512-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N|mint:MINT-6178112(identity) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N|mint:MINT-6178110(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela 2.11)|taxid:9606(Homo sapiens) - 2008/02/12 2014/10/16 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:9FB80A28F214B026|rigid:6SE9ipjIIQGrtHTyhdSNO9KjoKc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3U4 uniprotkb:Q8WVM7 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667475|mint:MINT-6178106|imex:IM-11512-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N|mint:MINT-6178112(identity) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178114(identity) - - - figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela 2.11)|taxid:9606(Homo sapiens) - 2008/02/12 2014/10/16 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:9FB80A28F214B026|rigid:6SE9ipjIIQGrtHTyhdSNO9KjoKc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P54274 uniprotkb:Q8WVM7 intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7667591|mint:MINT-6178136|imex:IM-11512-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N|mint:MINT-6178142(identity) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178144(identity) - - - figure legend:f2B F2D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/12 2014/10/16 rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:490D03C0F645E227|rigid:3rNeT0SU7+iFNYy6Wqiu5qHpaMU false myc tag:?-?(MINT-6178157) mutation decreasing interaction:1-72(MINT-6178151)|flag tag:?-?(MINT-6178149) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q8WVM7 uniprotkb:Q9UQE7 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7667631|mint:MINT-6178160|imex:IM-11512-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178162(identity) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N|mint:MINT-6178168(identity) - - - figure legend:f2C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:F3716D5B92D63D7E|rigid:GE5KZbC2WzcpBYZmJOmeUhglEtw false flag tag:?-?(MINT-6178165) - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:P54274 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7667661|mint:MINT-6178188|imex:IM-11512-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178190(identity) refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N|mint:MINT-6178196(identity) - - - figure legend:f2E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606 intact-crc:A0030A0FF4EDD49E|rigid:3rNeT0SU7+iFNYy6Wqiu5qHpaMU false green fluorescent protein tag:?-?(MINT-6178193)|binding-associated region:1-72(MINT-6178203) myc tag:?-?(MINT-6178197) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N3U4 uniprotkb:Q9UQE7 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7667646|mint:MINT-6178177|imex:IM-11512-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N|mint:MINT-6178181(identity) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N|mint:MINT-6178179(identity) - - - figure legend:f2C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/12 2014/10/16 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:B95D3F8F7E69CF3B|rigid:w/sZEFE8cn/txVq+PzOizMOJHYE false flag tag:?-?(MINT-6178182) - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q9BSI4 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-717399|uniprotkb:Q9H904|uniprotkb:Q9UHC2|uniprotkb:B3W5Q7|ensembl:ENSP00000267415|ensembl:ENSP00000495019 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:tinf2_human(display_long)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7667700|mint:MINT-6178228|imex:IM-11512-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178230(identity) refseq:NP_001092744.1|refseq:NP_036593.2|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|ensembl:ENSG00000284915(gene)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:1904356"(regulation of telomere maintenance via telomere lengthening)|ensembl:ENST00000267415(transcript)|interpro:IPR029400|interpro:IPR039098|mint:Q9BSI4|rcsb pdb:3BQO|rcsb pdb:3BU8|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|ensembl:ENST00000646576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|go:"GO:0000783"(nuclear telomere cap complex)|reactome:R-HSA-171319|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0010370"(perinucleolar chromocenter)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0016233"(telomere capping)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0032202"(telomere assembly)|ensembl:ENSG00000092330(gene)|dip:DIP-29413N|mint:MINT-6178236(identity) - - - figure legend:f3A F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:l/sNYfQWtGUBmGDKBRAluwdaiag9606 intact-crc:12AFFE2A94967EA0|rigid:uQ1onzn37oICVnz03NlouXVbRDc false flag tag:?-?(MINT-6178233)|mutation decreasing interaction:1-72(MINT-6178231) green fluorescent protein tag:?-?(MINT-6178237)|binding-associated region:1-180(MINT-6178240) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WVM7 uniprotkb:O60216 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0096"(pull down) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667737|mint:MINT-6178206|imex:IM-11512-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178208(identity) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N|mint:MINT-6178214(identity) - - - figure legend:f2F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:CFBF6329E473A369|rigid:RNUnbz2KS6hKbqoW7z9RsB2qMT4 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q9UQE7 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0096"(pull down) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667737|mint:MINT-6178206|imex:IM-11512-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178208(identity) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N|mint:MINT-6178212(identity) - - - figure legend:f2F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:CFBF6329E473A369|rigid:RNUnbz2KS6hKbqoW7z9RsB2qMT4 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:P54274 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym) psi-mi:"MI:0096"(pull down) Canudas et al. (2007) pubmed:17962804|imex:IM-11512|mint:MINT-6178082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7667737|mint:MINT-6178206|imex:IM-11512-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N|mint:MINT-6178208(identity) refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N|mint:MINT-6178210(identity) - - - figure legend:f2F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/12 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606 intact-crc:CFBF6329E473A369|rigid:RNUnbz2KS6hKbqoW7z9RsB2qMT4 false - myc tag:?-?(MINT-6178225) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)