#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O06462 uniprotkb:O06460 intact:EBI-2014042|ensemblbacteria:VCU54745 intact:EBI-2014049|ensemblbacteria:VCU54747 psi-mi:o06462_theth(display_long)|uniprotkb:narI(gene name)|psi-mi:narI(display_short)|uniprotkb:TTHNP4_00153(orf name) psi-mi:o06460_theth(display_long)|uniprotkb:narH(gene name)|psi-mi:narH(display_short)|uniprotkb:TTHNP4_00155(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014061|imex:IM-20133-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003816(Nitrate reductase, gamma subunit)|interpro:IPR023234|interpro:IPR036197|ensemblbacteria:TTHNP4_00153(gene)|ensemblbacteria:VCU54745(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0046872"(metal ion binding) interpro:IPR017896|interpro:IPR006547(Nitrate reductase, beta subunit)|interpro:IPR029263|interpro:IPR038262|ensemblbacteria:TTHNP4_00155(gene)|ensemblbacteria:VCU54747(transcript)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:LiwXEjJdpH4TvQ5nNRp+RtZMjhA274 rogid:3zT/IUoFxFFWZ35mGfLMxXmIs94274 intact-crc:9C5604FAF65CBD61|rigid:syW+NbrGEGAq5A1LdzrmjhuDqnc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06462 uniprotkb:O06459 intact:EBI-2014042|ensemblbacteria:VCU54745 intact:EBI-2014066|uniprotkb:Q934S1|ensemblbacteria:VCU54748 psi-mi:o06462_theth(display_long)|uniprotkb:narI(gene name)|psi-mi:narI(display_short)|uniprotkb:TTHNP4_00153(orf name) psi-mi:o06459_theth(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:TTHNP4_00156(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014082|imex:IM-20133-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003816(Nitrate reductase, gamma subunit)|interpro:IPR023234|interpro:IPR036197|ensemblbacteria:TTHNP4_00153(gene)|ensemblbacteria:VCU54745(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0046872"(metal ion binding) interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027467|interpro:IPR037943|ensemblbacteria:TTHNP4_00156(gene)|ensemblbacteria:VCU54748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:LiwXEjJdpH4TvQ5nNRp+RtZMjhA274 rogid:7SO0AEPKHxFqXNuu1JwsZHbGWcI274 intact-crc:9E8E0560317C1B9F|rigid:5UeT8cYbM7sUzYWwHhd2UnTlyU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06462 uniprotkb:Q934F6 intact:EBI-2014042|ensemblbacteria:VCU54745 intact:EBI-2014086|ensemblbacteria:VCU54749 psi-mi:o06462_theth(display_long)|uniprotkb:narI(gene name)|psi-mi:narI(display_short)|uniprotkb:TTHNP4_00153(orf name) psi-mi:q934f6_theth(display_long)|uniprotkb:narC(gene name)|psi-mi:narC(display_short)|uniprotkb:cycA_1(gene name synonym)|uniprotkb:TTHNP4_00157(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014095|imex:IM-20133-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003816(Nitrate reductase, gamma subunit)|interpro:IPR023234|interpro:IPR036197|ensemblbacteria:TTHNP4_00153(gene)|ensemblbacteria:VCU54745(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0046872"(metal ion binding) interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|ensemblbacteria:TTHNP4_00157(gene)|ensemblbacteria:VCU54749(transcript)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:LiwXEjJdpH4TvQ5nNRp+RtZMjhA274 rogid:SlJ+ALOGuIIClsWfJ1tYQpu2WE0274 intact-crc:9E1B47C688667C71|rigid:2UNeIWWlTYR6kMeckx6fFYy6dgM false - sufficient binding region:242-262 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06459 uniprotkb:O06461 intact:EBI-2014066|uniprotkb:Q934S1|ensemblbacteria:VCU54748 intact:EBI-2014099|ensemblbacteria:VCU54746 psi-mi:o06459_theth(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:TTHNP4_00156(orf name) psi-mi:o06461_theth(display_long)|uniprotkb:narJ(gene name)|psi-mi:narJ(display_short)|uniprotkb:TTHNP4_00154(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014106|imex:IM-20133-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027467|interpro:IPR037943|ensemblbacteria:TTHNP4_00156(gene)|ensemblbacteria:VCU54748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR020945|interpro:IPR003765(Nitrate reductase, delta subunit)|interpro:IPR036411|refseq:WP_014511193.1|ensemblbacteria:TTHNP4_00154(gene)|ensemblbacteria:VCU54746(transcript)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:7SO0AEPKHxFqXNuu1JwsZHbGWcI274 rogid:UeBjdBDJ4CP4EtYcf/OPfEh9mWw274 intact-crc:0714C7DB56519146|rigid:jP+3iHb3Ajwo9K22KNrNvOQCU0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06459 uniprotkb:O06461 intact:EBI-2014066|uniprotkb:Q934S1|ensemblbacteria:VCU54748 intact:EBI-2014099|ensemblbacteria:VCU54746 psi-mi:o06459_theth(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:TTHNP4_00156(orf name) psi-mi:o06461_theth(display_long)|uniprotkb:narJ(gene name)|psi-mi:narJ(display_short)|uniprotkb:TTHNP4_00154(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014110|imex:IM-20133-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027467|interpro:IPR037943|ensemblbacteria:TTHNP4_00156(gene)|ensemblbacteria:VCU54748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR020945|interpro:IPR003765(Nitrate reductase, delta subunit)|interpro:IPR036411|refseq:WP_014511193.1|ensemblbacteria:TTHNP4_00154(gene)|ensemblbacteria:VCU54746(transcript)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:7SO0AEPKHxFqXNuu1JwsZHbGWcI274 rogid:UeBjdBDJ4CP4EtYcf/OPfEh9mWw274 intact-crc:0E3ABBD27FE7E79A|rigid:jP+3iHb3Ajwo9K22KNrNvOQCU0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06459 uniprotkb:O06459 intact:EBI-2014066|uniprotkb:Q934S1|ensemblbacteria:VCU54748 intact:EBI-2014066|uniprotkb:Q934S1|ensemblbacteria:VCU54748 psi-mi:o06459_theth(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:TTHNP4_00156(orf name) psi-mi:o06459_theth(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:TTHNP4_00156(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014127|imex:IM-20133-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027467|interpro:IPR037943|ensemblbacteria:TTHNP4_00156(gene)|ensemblbacteria:VCU54748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027467|interpro:IPR037943|ensemblbacteria:TTHNP4_00156(gene)|ensemblbacteria:VCU54748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:7SO0AEPKHxFqXNuu1JwsZHbGWcI274 rogid:7SO0AEPKHxFqXNuu1JwsZHbGWcI274 intact-crc:A248111B79DAFABB|rigid:HK/qvWHdNMkKU4S1j7mITe5RkdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06459 uniprotkb:O06460 intact:EBI-2014066|uniprotkb:Q934S1|ensemblbacteria:VCU54748 intact:EBI-2014049|ensemblbacteria:VCU54747 psi-mi:o06459_theth(display_long)|uniprotkb:narG(gene name)|psi-mi:narG(display_short)|uniprotkb:TTHNP4_00156(orf name) psi-mi:o06460_theth(display_long)|uniprotkb:narH(gene name)|psi-mi:narH(display_short)|uniprotkb:TTHNP4_00155(orf name) psi-mi:"MI:0018"(two hybrid) Zafra et al. (2005) pubmed:15937161|imex:IM-20133 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014141|imex:IM-20133-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006468(Nitrate reductase, alpha subunit)|interpro:IPR006655(Molybdopterin oxidoreductase, prokaryotic, conserved site)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006657(Molydopterin dinucleotide-binding region)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027467|interpro:IPR037943|ensemblbacteria:TTHNP4_00156(gene)|ensemblbacteria:VCU54748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR017896|interpro:IPR006547(Nitrate reductase, beta subunit)|interpro:IPR029263|interpro:IPR038262|ensemblbacteria:TTHNP4_00155(gene)|ensemblbacteria:VCU54747(transcript)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0009325"(nitrate reductase complex)|go:"GO:0042126"(nitrate metabolic process) - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/10/17 2014/10/16 rogid:7SO0AEPKHxFqXNuu1JwsZHbGWcI274 rogid:3zT/IUoFxFFWZ35mGfLMxXmIs94274 intact-crc:B433E41C97138F92|rigid:pG9q8cfIsHgFLlTiDl9gEUCg+2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)