#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P31905	uniprotkb:P31903	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	intact:EBI-2265853|ensemblbacteria:AAP85772	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:hypd_cupnh(display_long)|uniprotkb:hypD(gene name)|psi-mi:hypD(display_short)|uniprotkb:PHG016(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2118906|imex:IM-17896-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	interpro:IPR002780(Hydrogenase formation HypD protein)|refseq:WP_011153941.1|interpro:IPR042243|interpro:IPR042244|ensemblbacteria:AAP85772(transcript)|ensemblbacteria:PHG016(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)	-	-	-	figure legend:1, 2|complex-properties:"In addition, several other Hyp proteins copurified with HypE. As shown in Figure 1B, immunoblot analysis using HypC- (9.8 kDa), HypD- (42 kDa), and HypF1-specific (40.7 kDa) antisera established that the other two bands present with molecular masses between 47.5 and 32.5 kDa were HypD and HypF1. Furthermore, detectable quantities of HypC were also present in the elution fractions."|comment:Immunoblot analysis of the Hyp proteins copurified with N-terminally Strep-tagged HypE in the hyp deletion strains indicate that both HypE and HypF1 were copuried. Furthermore, HypC and HypD copurified with HypE as a unit. Finally, their interaction with HypE was significantly destabilized by deletion of hypF1 and hypF2.|comment:HypB, HypE minus strain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	rogid:mR73V3j1at3Wti0YbmvyqKm/NSE381666	intact-crc:08EB2C31BC5D9030|rigid:kcRZPlJ2rDycJWCr0GmiedNIZrc	false	tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31905	uniprotkb:P45805	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	intact:EBI-2265845|ensemblbacteria:AAP85770	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:hypf1_cupnh(display_long)|uniprotkb:hypF1(gene name)|psi-mi:hypF1(display_short)|uniprotkb:hypF(gene name synonym)|uniprotkb:PHG014(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2118906|imex:IM-17896-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	refseq:WP_011153939.1|interpro:IPR041440|ensemblbacteria:AAP85770(transcript)|ensemblbacteria:PHG014(gene)	-	-	-	figure legend:1, 2|complex-properties:"In addition, several other Hyp proteins copurified with HypE. As shown in Figure 1B, immunoblot analysis using HypC- (9.8 kDa), HypD- (42 kDa), and HypF1-specific (40.7 kDa) antisera established that the other two bands present with molecular masses between 47.5 and 32.5 kDa were HypD and HypF1. Furthermore, detectable quantities of HypC were also present in the elution fractions."|comment:Immunoblot analysis of the Hyp proteins copurified with N-terminally Strep-tagged HypE in the hyp deletion strains indicate that both HypE and HypF1 were copuried. Furthermore, HypC and HypD copurified with HypE as a unit. Finally, their interaction with HypE was significantly destabilized by deletion of hypF1 and hypF2.|comment:HypB, HypE minus strain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	rogid:aE4blU/id+EV7DEaq2nVo3Z3b1Y381666	intact-crc:08EB2C31BC5D9030|rigid:kcRZPlJ2rDycJWCr0GmiedNIZrc	false	tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31905	uniprotkb:P31900	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	intact:EBI-2118899|ensemblbacteria:AAP85771	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:hypc_cupnh(display_long)|uniprotkb:hypC(gene name)|psi-mi:hypC(display_short)|uniprotkb:PHG015(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2118906|imex:IM-17896-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	interpro:IPR019812|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|ensemblbacteria:AAP85771(transcript)|ensemblbacteria:PHG015(gene)	-	-	-	figure legend:1, 2|complex-properties:"In addition, several other Hyp proteins copurified with HypE. As shown in Figure 1B, immunoblot analysis using HypC- (9.8 kDa), HypD- (42 kDa), and HypF1-specific (40.7 kDa) antisera established that the other two bands present with molecular masses between 47.5 and 32.5 kDa were HypD and HypF1. Furthermore, detectable quantities of HypC were also present in the elution fractions."|comment:Immunoblot analysis of the Hyp proteins copurified with N-terminally Strep-tagged HypE in the hyp deletion strains indicate that both HypE and HypF1 were copuried. Furthermore, HypC and HypD copurified with HypE as a unit. Finally, their interaction with HypE was significantly destabilized by deletion of hypF1 and hypF2.|comment:HypB, HypE minus strain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	rogid:tlzmjVRGB+j4LcWRQ3dzsMA4/Mw381666	intact-crc:08EB2C31BC5D9030|rigid:kcRZPlJ2rDycJWCr0GmiedNIZrc	false	tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P45805	uniprotkb:P31905	intact:EBI-2265845|ensemblbacteria:AAP85770	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	psi-mi:hypf1_cupnh(display_long)|uniprotkb:hypF1(gene name)|psi-mi:hypF1(display_short)|uniprotkb:hypF(gene name synonym)|uniprotkb:PHG014(locus name)	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265875|imex:IM-17896-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011153939.1|interpro:IPR041440|ensemblbacteria:AAP85770(transcript)|ensemblbacteria:PHG014(gene)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	-	-	-	figure legend:2|complex-properties:"In addition, several other Hyp proteins copurified with HypE. As shown in Figure 1B, immunoblot analysis using HypC- (9.8 kDa), HypD- (42 kDa), and HypF1-specific (40.7 kDa) antisera established that the other two bands present with molecular masses between 47.5 and 32.5 kDa were HypD and HypF1. Furthermore, detectable quantities of HypC were also present in the elution fractions."|comment:Immunoblot analysis of the Hyp proteins copurified with N-terminally Strep-tagged HypE in the hyp deletion strains indicate that both HypE and HypF1 were copuried. Furthermore, HypC and HypD copurified with HypE as a unit. Finally, their interaction with HypE was significantly destabilized by deletion of hypF1 and hypF2.|comment:HypC, HypD minus strain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:aE4blU/id+EV7DEaq2nVo3Z3b1Y381666	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	intact-crc:7D66E2752A46DA62|rigid:9Q9VGxOXswFXGsS0ckvs7Jv/a94	false	-	tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31905	uniprotkb:P31900	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	intact:EBI-2118899|ensemblbacteria:AAP85771	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:hypc_cupnh(display_long)|uniprotkb:hypC(gene name)|psi-mi:hypC(display_short)|uniprotkb:PHG015(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265884|imex:IM-17896-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	interpro:IPR019812|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|ensemblbacteria:AAP85771(transcript)|ensemblbacteria:PHG015(gene)	-	-	-	figure legend:2|complex-properties:"In addition, several other Hyp proteins copurified with HypE. As shown in Figure 1B, immunoblot analysis using HypC- (9.8 kDa), HypD- (42 kDa), and HypF1-specific (40.7 kDa) antisera established that the other two bands present with molecular masses between 47.5 and 32.5 kDa were HypD and HypF1. Furthermore, detectable quantities of HypC were also present in the elution fractions."|comment:Immunoblot analysis of the Hyp proteins copurified with N-terminally Strep-tagged HypE in the hyp deletion strains indicate that both HypE and HypF1 were copuried. Furthermore, HypC and HypD copurified with HypE as a unit. Finally, their interaction with HypE was significantly destabilized by deletion of hypF1 and hypF2.|comment:HypF minus strain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	rogid:tlzmjVRGB+j4LcWRQ3dzsMA4/Mw381666	intact-crc:0FE8A8EFF1B2D645|rigid:WtDcGOkWt4QHq+nw32+4Ow8jCNE	false	tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31905	uniprotkb:P31903	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	intact:EBI-2265853|ensemblbacteria:AAP85772	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:hypd_cupnh(display_long)|uniprotkb:hypD(gene name)|psi-mi:hypD(display_short)|uniprotkb:PHG016(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265884|imex:IM-17896-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	interpro:IPR002780(Hydrogenase formation HypD protein)|refseq:WP_011153941.1|interpro:IPR042243|interpro:IPR042244|ensemblbacteria:AAP85772(transcript)|ensemblbacteria:PHG016(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)	-	-	-	figure legend:2|complex-properties:"In addition, several other Hyp proteins copurified with HypE. As shown in Figure 1B, immunoblot analysis using HypC- (9.8 kDa), HypD- (42 kDa), and HypF1-specific (40.7 kDa) antisera established that the other two bands present with molecular masses between 47.5 and 32.5 kDa were HypD and HypF1. Furthermore, detectable quantities of HypC were also present in the elution fractions."|comment:Immunoblot analysis of the Hyp proteins copurified with N-terminally Strep-tagged HypE in the hyp deletion strains indicate that both HypE and HypF1 were copuried. Furthermore, HypC and HypD copurified with HypE as a unit. Finally, their interaction with HypE was significantly destabilized by deletion of hypF1 and hypF2.|comment:HypF minus strain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	rogid:mR73V3j1at3Wti0YbmvyqKm/NSE381666	intact-crc:0FE8A8EFF1B2D645|rigid:WtDcGOkWt4QHq+nw32+4Ow8jCNE	false	tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31900	uniprotkb:P22320	intact:EBI-2118899|ensemblbacteria:AAP85771	intact:EBI-2118910|uniprotkb:Q7WXN0|ensemblbacteria:AAP85844	psi-mi:hypc_cupnh(display_long)|uniprotkb:hypC(gene name)|psi-mi:hypC(display_short)|uniprotkb:PHG015(locus name)	psi-mi:hoxh_cupnh(display_long)|uniprotkb:hoxH(gene name)|psi-mi:hoxH(display_short)|uniprotkb:PHG091(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265894|imex:IM-17896-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019812|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|ensemblbacteria:AAP85771(transcript)|ensemblbacteria:PHG015(gene)	interpro:IPR001501(Nickel-dependent hydrogenase, large subunit)|interpro:IPR018194|refseq:WP_011154013.1|interpro:IPR029014|ensemblbacteria:AAP85844(transcript)|ensemblbacteria:PHG091(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0016151"(nickel cation binding)|go:"GO:0047985"(hydrogen dehydrogenase activity)	-	-	-	figure legend:5|comment:Deletion of hypF destabilized the interaction between HypC, HypD, and HypE.|comment:hypF deletion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:tlzmjVRGB+j4LcWRQ3dzsMA4/Mw381666	rogid:Lsj2rRySuididmoEBPxENEB6Vc8381666	intact-crc:3ED43191C2F2A9F9|rigid:xp3PJxHeWmRIL1LUAu2m/J5L65E	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31900	uniprotkb:P45805	intact:EBI-2118899|ensemblbacteria:AAP85771	intact:EBI-2265845|ensemblbacteria:AAP85770	psi-mi:hypc_cupnh(display_long)|uniprotkb:hypC(gene name)|psi-mi:hypC(display_short)|uniprotkb:PHG015(locus name)	psi-mi:hypf1_cupnh(display_long)|uniprotkb:hypF1(gene name)|psi-mi:hypF1(display_short)|uniprotkb:hypF(gene name synonym)|uniprotkb:PHG014(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265894|imex:IM-17896-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019812|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|ensemblbacteria:AAP85771(transcript)|ensemblbacteria:PHG015(gene)	refseq:WP_011153939.1|interpro:IPR041440|ensemblbacteria:AAP85770(transcript)|ensemblbacteria:PHG014(gene)	-	-	-	figure legend:5|comment:Deletion of hypF destabilized the interaction between HypC, HypD, and HypE.|comment:hypF deletion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:tlzmjVRGB+j4LcWRQ3dzsMA4/Mw381666	rogid:aE4blU/id+EV7DEaq2nVo3Z3b1Y381666	intact-crc:3ED43191C2F2A9F9|rigid:xp3PJxHeWmRIL1LUAu2m/J5L65E	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31900	uniprotkb:P31903	intact:EBI-2118899|ensemblbacteria:AAP85771	intact:EBI-2265853|ensemblbacteria:AAP85772	psi-mi:hypc_cupnh(display_long)|uniprotkb:hypC(gene name)|psi-mi:hypC(display_short)|uniprotkb:PHG015(locus name)	psi-mi:hypd_cupnh(display_long)|uniprotkb:hypD(gene name)|psi-mi:hypD(display_short)|uniprotkb:PHG016(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265894|imex:IM-17896-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019812|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|ensemblbacteria:AAP85771(transcript)|ensemblbacteria:PHG015(gene)	interpro:IPR002780(Hydrogenase formation HypD protein)|refseq:WP_011153941.1|interpro:IPR042243|interpro:IPR042244|ensemblbacteria:AAP85772(transcript)|ensemblbacteria:PHG016(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)	-	-	-	figure legend:5|comment:Deletion of hypF destabilized the interaction between HypC, HypD, and HypE.|comment:hypF deletion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:tlzmjVRGB+j4LcWRQ3dzsMA4/Mw381666	rogid:mR73V3j1at3Wti0YbmvyqKm/NSE381666	intact-crc:3ED43191C2F2A9F9|rigid:xp3PJxHeWmRIL1LUAu2m/J5L65E	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31900	uniprotkb:P31905	intact:EBI-2118899|ensemblbacteria:AAP85771	intact:EBI-2265828|uniprotkb:P70739|ensemblbacteria:AAP85773	psi-mi:hypc_cupnh(display_long)|uniprotkb:hypC(gene name)|psi-mi:hypC(display_short)|uniprotkb:PHG015(locus name)	psi-mi:hype_cupnh(display_long)|uniprotkb:Hydrogenase maturation factor HypE(gene name synonym)|uniprotkb:PHG017(locus name)|uniprotkb:hypE(gene name)|psi-mi:hypE(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Jones et al. (2004)	pubmed:15491154|imex:IM-17896	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	taxid:381666(raleh)|taxid:381666("Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2265894|imex:IM-17896-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019812|interpro:IPR001109("Hydrogenase expression/formation protein (HUPF/HYPC)")|ensemblbacteria:AAP85771(transcript)|ensemblbacteria:PHG015(gene)	interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR011854(Hydrogenase expression/formation protein HypE)|interpro:IPR016188(PurM, N-terminal-like)|refseq:WP_011153942.1|interpro:IPR036676|interpro:IPR036921|ensemblbacteria:AAP85773(transcript)|ensemblbacteria:PHG017(gene)|go:"GO:0016829"(lyase activity)	-	-	-	figure legend:5|comment:Deletion of hypF destabilized the interaction between HypC, HypD, and HypE.|comment:hypF deletion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/11/25	2014/10/16	rogid:tlzmjVRGB+j4LcWRQ3dzsMA4/Mw381666	rogid:Pb4yklBQ9evCmYPJ0E6NaXW+LQA381666	intact-crc:3ED43191C2F2A9F9|rigid:xp3PJxHeWmRIL1LUAu2m/J5L65E	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)