#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P41411	uniprotkb:O14170	intact:EBI-1207853|ensemblfungi:"SPBC14C8.07c.1:pep"	intact:EBI-1185414|ensemblfungi:"SPAC4D7.03.1:pep"	psi-mi:cdc18_schpo(display_long)|uniprotkb:cdc18(gene name)|psi-mi:cdc18(display_short)|uniprotkb:SPBC14C8.07c(orf name)	psi-mi:pop2_schpo(display_long)|uniprotkb:Proteolysis factor sud1(gene name synonym)|uniprotkb:pop2(gene name)|psi-mi:pop2(display_short)|uniprotkb:sud1(gene name synonym)|uniprotkb:SPAC4D7.03(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jallepalli et al. (1998)	pubmed:9653157|imex:IM-19935	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1208595|imex:IM-19935-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595910.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|reactome:R-SPO-68689|reactome:R-SPO-68962|reactome:R-SPO-69017|interpro:IPR027417|reactome:R-SPO-176187|ensemblfungi:SPBC14C8.07c(gene)|ensemblfungi:SPBC14C8.07c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0051301"(cell division)|go:"GO:0140530"(MCM complex loading)|go:"GO:1902985"(mitotic pre-replicative complex assembly)|go:"GO:1903468"(positive regulation of DNA replication initiation)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR036388|interpro:IPR036390|reactome:R-SPO-68949|interpro:IPR041083|reactome:R-SPO-68827|reactome:R-SPO-68867	refseq:NP_594956.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|ensemblfungi:SPAC4D7.03(gene)|ensemblfungi:SPAC4D7.03.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0070647"(protein modification by small protein conjugation or removal)|go:"GO:1903467"(negative regulation of mitotic DNA replication initiation)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O14170|interpro:IPR036047|interpro:IPR036322	-	-	-	figure legend:Figure 5A and 5B.|comment:Interaction between Pop2 and Cdc18 was detected in extracts from cells expressing HA-tagged pop2 and myc-tagged cdc18. This interaction is disrupted with mutant cdc18 indicating that pop2 only interacts with phosphorylated cdc18.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2007/02/28	2014/10/16	rogid:jB9IGO2TuHbrQngQUhh0PiIudgg284812	rogid:Te5GmNzUBSnfbMfLIGrHi+6u7/A284812	intact-crc:3399214C6F664E15|rigid:ioesbpXyhUUoqikiWB6BtlcsK20	false	myc tag:?-?|mutation disrupting interaction:104-104,10-10,60-60,101-101,46-46,4-4	ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41411	uniprotkb:O14170	intact:EBI-1207853|ensemblfungi:"SPBC14C8.07c.1:pep"	intact:EBI-1185414|ensemblfungi:"SPAC4D7.03.1:pep"	psi-mi:cdc18_schpo(display_long)|uniprotkb:cdc18(gene name)|psi-mi:cdc18(display_short)|uniprotkb:SPBC14C8.07c(orf name)	psi-mi:pop2_schpo(display_long)|uniprotkb:Proteolysis factor sud1(gene name synonym)|uniprotkb:pop2(gene name)|psi-mi:pop2(display_short)|uniprotkb:sud1(gene name synonym)|uniprotkb:SPAC4D7.03(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jallepalli et al. (1998)	pubmed:9653157|imex:IM-19935	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1210921|imex:IM-19935-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595910.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|reactome:R-SPO-68689|reactome:R-SPO-68962|reactome:R-SPO-69017|interpro:IPR027417|reactome:R-SPO-176187|ensemblfungi:SPBC14C8.07c(gene)|ensemblfungi:SPBC14C8.07c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0051301"(cell division)|go:"GO:0140530"(MCM complex loading)|go:"GO:1902985"(mitotic pre-replicative complex assembly)|go:"GO:1903468"(positive regulation of DNA replication initiation)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR036388|interpro:IPR036390|reactome:R-SPO-68949|interpro:IPR041083|reactome:R-SPO-68827|reactome:R-SPO-68867	refseq:NP_594956.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|ensemblfungi:SPAC4D7.03(gene)|ensemblfungi:SPAC4D7.03.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0070647"(protein modification by small protein conjugation or removal)|go:"GO:1903467"(negative regulation of mitotic DNA replication initiation)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O14170|interpro:IPR036047|interpro:IPR036322	-	-	-	figure legend:Figure 5A.|comment:Interaction between Pop2 and Cdc18 was detected in extracts from cells expressing HA-tagged pop2 and myc-tagged cdc18.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2007/02/28	2014/10/16	rogid:jB9IGO2TuHbrQngQUhh0PiIudgg284812	rogid:Te5GmNzUBSnfbMfLIGrHi+6u7/A284812	intact-crc:9870F5FCC6A8D3EA|rigid:ioesbpXyhUUoqikiWB6BtlcsK20	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)