#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O14417 uniprotkb:P78972 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0018"(two hybrid) Kim et al. (1998) pubmed:9461438|imex:IM-19006 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1553646|imex:IM-19006-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 - crc64:DC9D1D213450C925 crc64:52E021FD4EECE5DE figure legend:Fig 1a, 1b, 1d, 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/08 2014/10/16 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 intact-crc:D201EE524EC26299|rigid:cRr6dtV/2+SWjn6J56fRj19tFMc false - necessary binding region:118-146|mutation disrupting interaction:131-131,132-132 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14417 uniprotkb:P78972 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0096"(pull down) Kim et al. (1998) pubmed:9461438|imex:IM-19006 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1553658|imex:IM-19006-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 - crc64:DC9D1D213450C925 crc64:52E021FD4EECE5DE figure legend:Fig 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/08 2014/10/16 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 intact-crc:1D50947EA35DF589|rigid:cRr6dtV/2+SWjn6J56fRj19tFMc false 35s radiolabel:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O14417 uniprotkb:P78972 intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0096"(pull down) Kim et al. (1998) pubmed:9461438|imex:IM-19006 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1553672|imex:IM-19006-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 - crc64:DC9D1D213450C925 crc64:52E021FD4EECE5DE figure legend:Fig 5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/08 2014/10/16 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 intact-crc:00F412E8994966C0|rigid:cRr6dtV/2+SWjn6J56fRj19tFMc false glutathione s tranferase tag:n-n mutation disrupting interaction:131-131,132-132 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)