#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P40965	uniprotkb:Q12175	intact:EBI-11371|ensemblfungi:YFL003C|uniprotkb:D6VTM6	intact:EBI-11377|ensemblfungi:YDL154W|uniprotkb:D6VRJ6	psi-mi:msh4_yeast(display_long)|uniprotkb:MSH4(gene name)|psi-mi:MSH4(display_short)|uniprotkb:YFL003C(locus name)	psi-mi:msh5_yeast(display_long)|uniprotkb:MSH5(gene name)|psi-mi:MSH5(display_short)|uniprotkb:D1542(orf name)|uniprotkb:YDL154W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Pochart et al. (1997)	pubmed:9374523|imex:IM-18928	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1373447|imex:IM-18928-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YFL003C(gene)|ensemblfungi:YFL003C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005524"(ATP binding)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|refseq:NP_116652.1|sgd:S000001891|mint:P40965|dip:DIP-2426N	ensemblfungi:YDL154W(gene)|ensemblfungi:YDL154W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|refseq:NP_010127.1|sgd:S000002313|dip:DIP-1457N	-	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/23	2014/10/16	rogid:iFhkRrFx9rw2iRzg7gJfv5eZwXk559292	rogid:2QvKzMcoV/+KZDA7pd5KfPB1hrc559292	intact-crc:AFAEB5F099CE9AC9|rigid:nA1ISHONzRR4X6C+F5A2QpFP3yo	false	fusion protein:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P40965	uniprotkb:P40965	intact:EBI-11371|ensemblfungi:YFL003C|uniprotkb:D6VTM6	intact:EBI-11371|ensemblfungi:YFL003C|uniprotkb:D6VTM6	psi-mi:msh4_yeast(display_long)|uniprotkb:MSH4(gene name)|psi-mi:MSH4(display_short)|uniprotkb:YFL003C(locus name)	psi-mi:msh4_yeast(display_long)|uniprotkb:MSH4(gene name)|psi-mi:MSH4(display_short)|uniprotkb:YFL003C(locus name)	psi-mi:"MI:0018"(two hybrid)	Pochart et al. (1997)	pubmed:9374523|imex:IM-18928	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1373459|imex:IM-18928-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YFL003C(gene)|ensemblfungi:YFL003C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005524"(ATP binding)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|refseq:NP_116652.1|sgd:S000001891|mint:P40965|dip:DIP-2426N	ensemblfungi:YFL003C(gene)|ensemblfungi:YFL003C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005524"(ATP binding)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|refseq:NP_116652.1|sgd:S000001891|mint:P40965|dip:DIP-2426N	-	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/23	2014/10/16	rogid:iFhkRrFx9rw2iRzg7gJfv5eZwXk559292	rogid:iFhkRrFx9rw2iRzg7gJfv5eZwXk559292	intact-crc:F21FE4A8A1855F43|rigid:9GRbYH22/WuNGNnzPD1CjDMTTeU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12175	uniprotkb:P40965	intact:EBI-11377|ensemblfungi:YDL154W|uniprotkb:D6VRJ6	intact:EBI-11371|ensemblfungi:YFL003C|uniprotkb:D6VTM6	psi-mi:msh5_yeast(display_long)|uniprotkb:MSH5(gene name)|psi-mi:MSH5(display_short)|uniprotkb:D1542(orf name)|uniprotkb:YDL154W(locus name)	psi-mi:msh4_yeast(display_long)|uniprotkb:MSH4(gene name)|psi-mi:MSH4(display_short)|uniprotkb:YFL003C(locus name)	psi-mi:"MI:0018"(two hybrid)	Pochart et al. (1997)	pubmed:9374523|imex:IM-18928	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1373489|imex:IM-18928-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL154W(gene)|ensemblfungi:YDL154W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|refseq:NP_010127.1|sgd:S000002313|dip:DIP-1457N	ensemblfungi:YFL003C(gene)|ensemblfungi:YFL003C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005524"(ATP binding)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0062128"(MutSgamma complex)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|refseq:NP_116652.1|sgd:S000001891|mint:P40965|dip:DIP-2426N	-	-	-	figure legend:2 and 4|comment:MSH5 mutations G643D, A644V, G648R and G821D did not affect the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/23	2017/11/08	rogid:2QvKzMcoV/+KZDA7pd5KfPB1hrc559292	rogid:iFhkRrFx9rw2iRzg7gJfv5eZwXk559292	intact-crc:D2FA03386DC1BA42|rigid:nA1ISHONzRR4X6C+F5A2QpFP3yo	false	mutation with no effect:643-643|mutation with no effect:644-644|mutation with no effect:648-648|mutation with no effect:821-821	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25847	uniprotkb:Q03834	intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8	intact:EBI-11383|ensemblfungi:YDR097C|uniprotkb:D6VS82	psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:msh6_yeast(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:YDR097C(locus name)|uniprotkb:YD8557.04C(orf name)|uniprotkb:PMS3(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)|uniprotkb:Postmeiotic segregation protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Pochart et al. (1997)	pubmed:9374523|imex:IM-18928	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1373525|imex:IM-18928-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N	ensemblfungi:YDR097C(gene)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|ensemblfungi:YDR097C_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|go:"GO:0005737"(cytoplasm)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|refseq:NP_010382.3|sgd:S000002504|mint:Q03834|dip:DIP-2423N	-	crc64:43FFD8A640138AE4	crc64:11A6883AADCFA222	figure legend:Table II|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/23	2014/10/16	rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292	rogid:IufLo1sfhfBnNLFLGR/VO5gkApI559292	intact-crc:76853CE624750120|rigid:YXOBvHYwU4PopCXtC0hy8v19tsg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)