#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15330	uniprotkb:P22812	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	intact-crc:35F3783BC7B6DA26|rigid:P8fnt4KOtoogIT2UqNuEk9eWhus	false	sufficient binding region:47-345	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15330	uniprotkb:P15330	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	intact-crc:7942A1E12F3002E9|rigid:aVV6xmDs/ELOo35wwEbUQvTh6B0	false	-	sufficient binding region:47-345	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03017	uniprotkb:P15330	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	intact-crc:5AF81E21909E37B1|rigid:YUloJ2l9wJFVD7cm3QpZPOdkSDc	false	-	sufficient binding region:47-345	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05652	uniprotkb:P15330	intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short)	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	intact-crc:2132A965F13F45B9|rigid:6jELBMnCU4vGrngEHVgHKX5zAoM	false	-	sufficient binding region:47-345	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03017	uniprotkb:P15330	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	intact-crc:739A5D5C95B44E17|rigid:YUloJ2l9wJFVD7cm3QpZPOdkSDc	false	sufficient binding region:215-500	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03017	uniprotkb:Q03017	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	intact-crc:CD508F58DB94097E|rigid:Ev8rkXpjTvdCr0J50IicN1WpA8o	false	sufficient binding region:215-500	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22812	uniprotkb:Q05652	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227	intact-crc:3FA7AD7B273ECE9F|rigid:CBP6+LAxAvEVwY1/uwqyn2iFqUM	false	-	sufficient binding region:26-129	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15330	uniprotkb:Q05652	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227	intact-crc:C026E433D960D292|rigid:6jELBMnCU4vGrngEHVgHKX5zAoM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15330	uniprotkb:P22812	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	intact-crc:6E5CA1CAC5007ABB|rigid:P8fnt4KOtoogIT2UqNuEk9eWhus	false	-	sufficient binding region:256-462	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22812	uniprotkb:Q05652	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N	-	-	-	figure legend:2, Table 1	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227	intact-crc:D61A240780CBF686|rigid:CBP6+LAxAvEVwY1/uwqyn2iFqUM	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9VEN1	uniprotkb:P22812	intact:EBI-133626|uniprotkb:Q7KJX2|uniprotkb:Q9U4I3|uniprotkb:Q9U6C0|uniprotkb:Q7KKC2|uniprotkb:Q9GQV1|uniprotkb:Q9U6C1|intact:EBI-868700|intact:EBI-3422596|ensemblmetazoa:FBpp0088478	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	psi-mi:flna_drome(display_long)|uniprotkb:cher(gene name)|psi-mi:cher(display_short)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Filamin1(gene name synonym)|uniprotkb:cheerio(gene name synonym)|uniprotkb:sko(gene name synonym)|uniprotkb:CG3937(orf name)	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524383.3|flybase:FBgn0014141|refseq:NP_732207.1|refseq:NP_001262656.1|go:"GO:0045214"(sarcomere organization)|ensemblmetazoa:FBgn0014141(gene)|ensemblmetazoa:FBtr0089471(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007616"(long-term memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008104"(protein localization)|go:"GO:0008302"(female germline ring canal formation, actin assembly)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030725"(germline ring canal formation)|go:"GO:0035182"(female germline ring canal outer rim)|go:"GO:0035183"(female germline ring canal inner rim)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-DME-114608|reactome:R-DME-446353|reactome:R-DME-5627123|go:"GO:0110069"(syncytial embryo cellularization)	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	intact:EBI-871910(intact-secondary)	-	-	figure legend:5	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:++xPEeu5Z1ZaL+pF0/UcA7kK7kE7227	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	intact-crc:8A1E182BB48EC16C|rigid:Txr1ZcFUAhbsFJ4/7HhIctBRf1g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08953	uniprotkb:Q9VEN1	intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188	intact:EBI-133626|uniprotkb:Q7KJX2|uniprotkb:Q9U4I3|uniprotkb:Q9U6C0|uniprotkb:Q7KKC2|uniprotkb:Q9GQV1|uniprotkb:Q9U6C1|intact:EBI-868700|intact:EBI-3422596|ensemblmetazoa:FBpp0088478	psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name)	psi-mi:flna_drome(display_long)|uniprotkb:cher(gene name)|psi-mi:cher(display_short)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Filamin1(gene name synonym)|uniprotkb:cheerio(gene name synonym)|uniprotkb:sko(gene name synonym)|uniprotkb:CG3937(orf name)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874	refseq:NP_524383.3|flybase:FBgn0014141|refseq:NP_732207.1|refseq:NP_001262656.1|go:"GO:0045214"(sarcomere organization)|ensemblmetazoa:FBgn0014141(gene)|ensemblmetazoa:FBtr0089471(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007616"(long-term memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008104"(protein localization)|go:"GO:0008302"(female germline ring canal formation, actin assembly)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030725"(germline ring canal formation)|go:"GO:0035182"(female germline ring canal outer rim)|go:"GO:0035183"(female germline ring canal inner rim)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-DME-114608|reactome:R-DME-446353|reactome:R-DME-5627123|go:"GO:0110069"(syncytial embryo cellularization)	intact:EBI-871914(intact-secondary)	-	-	figure legend:5	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227	rogid:++xPEeu5Z1ZaL+pF0/UcA7kK7kE7227	intact-crc:CAABBC7C6AA64F94|rigid:V12M+4OysOzUoX0zjU/Q8Lux3G8	false	-	sufficient binding region:696-903	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03017	uniprotkb:P15330	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393810	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	-	-	-	figure legend:3	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/09/11	2014/10/16	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	intact-crc:A1F02E8A27ECFC25|rigid:YUloJ2l9wJFVD7cm3QpZPOdkSDc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15330	uniprotkb:P22812	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393821	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	-	-	-	figure legend:3	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/09/11	2014/10/16	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	intact-crc:668F25EC3DBBD4C8|rigid:P8fnt4KOtoogIT2UqNuEk9eWhus	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15330	uniprotkb:Q03017	intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name)	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	-	-	-	figure legend:3	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/09/11	2014/10/16	rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	intact-crc:A60954E975E1A9E1|rigid:YUloJ2l9wJFVD7cm3QpZPOdkSDc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03017	uniprotkb:P22812	intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004	intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542	psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short)	psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702	refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N	-	-	-	figure legend:3	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/09/11	2014/10/16	rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227	rogid:v00LZV72cvvYVI5cCthONXIlmrs7227	intact-crc:DCDCFC32EA928101|rigid:LiPLNroXftMj2LTFvq34qYLxLF8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9VEN1	uniprotkb:P08953	intact:EBI-133626|uniprotkb:Q7KJX2|uniprotkb:Q9U4I3|uniprotkb:Q9U6C0|uniprotkb:Q7KKC2|uniprotkb:Q9GQV1|uniprotkb:Q9U6C1|intact:EBI-868700|intact:EBI-3422596|ensemblmetazoa:FBpp0088478	intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188	psi-mi:flna_drome(display_long)|uniprotkb:cher(gene name)|psi-mi:cher(display_short)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Filamin1(gene name synonym)|uniprotkb:cheerio(gene name synonym)|uniprotkb:sko(gene name synonym)|uniprotkb:CG3937(orf name)	psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name)	psi-mi:"MI:0018"(two hybrid)	Edwards et al. (1997)	pubmed:9367441	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1393880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524383.3|flybase:FBgn0014141|refseq:NP_732207.1|refseq:NP_001262656.1|go:"GO:0045214"(sarcomere organization)|ensemblmetazoa:FBgn0014141(gene)|ensemblmetazoa:FBtr0089471(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007616"(long-term memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008104"(protein localization)|go:"GO:0008302"(female germline ring canal formation, actin assembly)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030725"(germline ring canal formation)|go:"GO:0035182"(female germline ring canal outer rim)|go:"GO:0035183"(female germline ring canal inner rim)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-DME-114608|reactome:R-DME-446353|reactome:R-DME-5627123|go:"GO:0110069"(syncytial embryo cellularization)	refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/11	2014/10/16	rogid:++xPEeu5Z1ZaL+pF0/UcA7kK7kE7227	rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227	intact-crc:625C0E44C7D8DD24|rigid:V12M+4OysOzUoX0zjU/Q8Lux3G8	false	-	sufficient binding region:829-1036	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)