#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O46339	uniprotkb:P40427	intact:EBI-137488|intact:EBI-497943|intact:EBI-1558099|uniprotkb:Q8INL6|uniprotkb:O17427|uniprotkb:Q058V1|uniprotkb:Q4AB34|uniprotkb:Q59DX7|uniprotkb:Q6NR42|uniprotkb:Q7KQ21|uniprotkb:Q9VGY9|uniprotkb:Q8INL5|intact:EBI-3431899|ensemblmetazoa:FBpp0081732	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:hth_drome(display_long)|uniprotkb:hth(gene name)|psi-mi:hth(display_short)|uniprotkb:dtl(gene name synonym)|uniprotkb:Homeobox protein dorsotonals(gene name synonym)|uniprotkb:CG17117(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0096"(pull down)	Rieckhof et al. (1997)	pubmed:9346235|imex:IM-19230	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1392894|imex:IM-19230-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476577.3|refseq:NP_001014613.2|refseq:NP_001027170.1|refseq:NP_476576.1|refseq:NP_476578.3|flybase:FBgn0001235|ensemblmetazoa:FBgn0001235(gene)|ensemblmetazoa:FBtr0082255(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035282"(segmentation)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0048735"(haltere morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000497"(positive regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|reactome:R-DME-390193	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	-	-	-	figure legend:8F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/10	2014/10/16	rogid:3+HaeG85WPZHxn++kVkx3QXQvXU7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	intact-crc:449F517A014C0FC8|rigid:s8bemnV/cDUFpN8KE0D+icTyLVw	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O46339	uniprotkb:P40427	intact:EBI-137488|intact:EBI-497943|intact:EBI-1558099|uniprotkb:Q8INL6|uniprotkb:O17427|uniprotkb:Q058V1|uniprotkb:Q4AB34|uniprotkb:Q59DX7|uniprotkb:Q6NR42|uniprotkb:Q7KQ21|uniprotkb:Q9VGY9|uniprotkb:Q8INL5|intact:EBI-3431899|ensemblmetazoa:FBpp0081732	intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515	psi-mi:hth_drome(display_long)|uniprotkb:hth(gene name)|psi-mi:hth(display_short)|uniprotkb:dtl(gene name synonym)|uniprotkb:Homeobox protein dorsotonals(gene name synonym)|uniprotkb:CG17117(orf name)	psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name)	psi-mi:"MI:0096"(pull down)	Rieckhof et al. (1997)	pubmed:9346235|imex:IM-19230	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1392904|imex:IM-19230-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476577.3|refseq:NP_001014613.2|refseq:NP_001027170.1|refseq:NP_476576.1|refseq:NP_476578.3|flybase:FBgn0001235|ensemblmetazoa:FBgn0001235(gene)|ensemblmetazoa:FBtr0082255(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035282"(segmentation)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0048735"(haltere morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000497"(positive regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|reactome:R-DME-390193	refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N	-	-	-	figure legend:8G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/10	2014/10/16	rogid:3+HaeG85WPZHxn++kVkx3QXQvXU7227	rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227	intact-crc:F6A77FAF84E52931|rigid:s8bemnV/cDUFpN8KE0D+icTyLVw	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)