#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40380 uniprotkb:P10815 intact:EBI-1187892|uniprotkb:O74373|ensemblfungi:"SPBC32F12.09.1:pep" intact:EBI-1187843|uniprotkb:Q9UU16|ensemblfungi:"SPBC582.03.1:pep" psi-mi:rum1_schpo(display_long)|uniprotkb:rum1(gene name)|psi-mi:rum1(display_short)|uniprotkb:SPBC32F12.09(orf name)|uniprotkb:p25-rum1(gene name synonym) psi-mi:cg23_schpo(display_long)|uniprotkb:cdc13(gene name)|psi-mi:cdc13(display_short)|uniprotkb:SPBC582.03(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Correa-Bordes et al. (1997) pubmed:9303310 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1214916 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596152.1|ensemblfungi:SPBC32F12.09(gene)|ensemblfungi:SPBC32F12.09.1(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) refseq:NP_595171.1|ensemblfungi:SPBC582.03(gene)|ensemblfungi:SPBC582.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0075297"(negative regulation of ascospore formation)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|go:"GO:0140445"(chromosome, telomeric repeat region)|dip:DIP-620N|reactome:R-SPO-69017|reactome:R-SPO-69202|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168 - - crc64:B2C267CF57F5FD36 figure legend:Figure 4.|comment:Shows that rum1 can specifically associate with cdc13 alone or complexed with cdc2 in vitro. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/15 2014/10/16 rogid:66UWvndQ1xihZmi/pEZbhdSJsxg284812 rogid:18Ti7CkkGHpRMlPyXO+5ENZFIn4284812 intact-crc:E612EB3D8A625CE8|rigid:SWIWhDKoVTsmnAkGjA/nM+JucSA false - 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40380 uniprotkb:P04551 intact:EBI-1187892|uniprotkb:O74373|ensemblfungi:"SPBC32F12.09.1:pep" intact:EBI-1187862|ensemblfungi:"SPBC11B10.09.1:pep" psi-mi:rum1_schpo(display_long)|uniprotkb:rum1(gene name)|psi-mi:rum1(display_short)|uniprotkb:SPBC32F12.09(orf name)|uniprotkb:p25-rum1(gene name synonym) psi-mi:cdk1_schpo(display_long)|uniprotkb:cdc2(gene name)|psi-mi:cdc2(display_short)|uniprotkb:swo2(gene name synonym)|uniprotkb:SPBC11B10.09(orf name)|uniprotkb:pi002(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk1(gene name synonym)|uniprotkb:Cell division control protein 2(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Correa-Bordes et al. (1997) pubmed:9303310 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1214916 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596152.1|ensemblfungi:SPBC32F12.09(gene)|ensemblfungi:SPBC32F12.09.1(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) refseq:NP_595629.1|reactome:R-SPO-176187|ensemblfungi:SPBC11B10.09(gene)|ensemblfungi:SPBC11B10.09.1(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0062123"(regulation of linear element maturation)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0072435"(response to mitotic G2 DNA damage checkpoint signaling)|go:"GO:0072441"(response to meiotic DNA replication checkpoint signaling)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0110045"(negative regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902424"(negative regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902845"(negative regulation of mitotic spindle elongation)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903380"(positive regulation of mitotic chromosome condensation)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1903467"(negative regulation of mitotic DNA replication initiation)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)|go:"GO:1904537"(negative regulation of mitotic telomere tethering at nuclear periphery)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905263"(positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:1905757"(negative regulation of primary cell septum biogenesis)|go:"GO:1905785"(negative regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990820"(response to mitotic DNA integrity checkpoint signaling)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-1076N|reactome:R-SPO-68962|reactome:R-SPO-69017|reactome:R-SPO-69202|reactome:R-SPO-68949|reactome:R-SPO-69656 - - - figure legend:Figure 4.|comment:Shows that rum1 can specifically associate with cdc13 alone or complexed with cdc2 in vitro. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/15 2014/10/16 rogid:66UWvndQ1xihZmi/pEZbhdSJsxg284812 rogid:Xm26f9FnmjG9I6P1hrk/9kWszzY284812 intact-crc:E612EB3D8A625CE8|rigid:SWIWhDKoVTsmnAkGjA/nM+JucSA false - 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40380 uniprotkb:P10815 intact:EBI-1187892|uniprotkb:O74373|ensemblfungi:"SPBC32F12.09.1:pep" intact:EBI-1187843|uniprotkb:Q9UU16|ensemblfungi:"SPBC582.03.1:pep" psi-mi:rum1_schpo(display_long)|uniprotkb:rum1(gene name)|psi-mi:rum1(display_short)|uniprotkb:SPBC32F12.09(orf name)|uniprotkb:p25-rum1(gene name synonym) psi-mi:cg23_schpo(display_long)|uniprotkb:cdc13(gene name)|psi-mi:cdc13(display_short)|uniprotkb:SPBC582.03(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Correa-Bordes et al. (1997) pubmed:9303310 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1224254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596152.1|ensemblfungi:SPBC32F12.09(gene)|ensemblfungi:SPBC32F12.09.1(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) refseq:NP_595171.1|ensemblfungi:SPBC582.03(gene)|ensemblfungi:SPBC582.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0075297"(negative regulation of ascospore formation)|go:"GO:0140013"(meiotic nuclear division)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|go:"GO:0140445"(chromosome, telomeric repeat region)|dip:DIP-620N|reactome:R-SPO-69017|reactome:R-SPO-69202|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168 - - crc64:B2C267CF57F5FD36 figure legend:Figure 4.|comment:Shows that rum1 can specifically associate with cdc13 alone or complexed with cdc2 in vitro. Also deletion of the destruction box in the cdc13-delta-90 mutant did not inhibit its binding with rum1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/15 2014/10/16 rogid:66UWvndQ1xihZmi/pEZbhdSJsxg284812 rogid:18Ti7CkkGHpRMlPyXO+5ENZFIn4284812 intact-crc:6D0302BA2932F3C6|rigid:/SsWw8S7eWnIf7jciwPmc83NUAM false - 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40380 uniprotkb:P04551 intact:EBI-1187892|uniprotkb:O74373|ensemblfungi:"SPBC32F12.09.1:pep" intact:EBI-1187862|ensemblfungi:"SPBC11B10.09.1:pep" psi-mi:rum1_schpo(display_long)|uniprotkb:rum1(gene name)|psi-mi:rum1(display_short)|uniprotkb:SPBC32F12.09(orf name)|uniprotkb:p25-rum1(gene name synonym) psi-mi:cdk1_schpo(display_long)|uniprotkb:cdc2(gene name)|psi-mi:cdc2(display_short)|uniprotkb:swo2(gene name synonym)|uniprotkb:SPBC11B10.09(orf name)|uniprotkb:pi002(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk1(gene name synonym)|uniprotkb:Cell division control protein 2(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Correa-Bordes et al. (1997) pubmed:9303310 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1215216 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596152.1|ensemblfungi:SPBC32F12.09(gene)|ensemblfungi:SPBC32F12.09.1(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) refseq:NP_595629.1|reactome:R-SPO-176187|ensemblfungi:SPBC11B10.09(gene)|ensemblfungi:SPBC11B10.09.1(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0062123"(regulation of linear element maturation)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0072435"(response to mitotic G2 DNA damage checkpoint signaling)|go:"GO:0072441"(response to meiotic DNA replication checkpoint signaling)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0110045"(negative regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902424"(negative regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902845"(negative regulation of mitotic spindle elongation)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903380"(positive regulation of mitotic chromosome condensation)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1903467"(negative regulation of mitotic DNA replication initiation)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)|go:"GO:1904537"(negative regulation of mitotic telomere tethering at nuclear periphery)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905263"(positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:1905757"(negative regulation of primary cell septum biogenesis)|go:"GO:1905785"(negative regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990820"(response to mitotic DNA integrity checkpoint signaling)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-1076N|reactome:R-SPO-68962|reactome:R-SPO-69017|reactome:R-SPO-69202|reactome:R-SPO-68949|reactome:R-SPO-69656 - - - figure legend:Figure 8.|comment:Rum1 kinase activity was detected with both anti-cdc2 and anti-cig1 antibodies. However, cig1 had been immunoprecipitated using cdc2, the authors state that the kinase activity it due to the formation a cig/cdc2 complex which phosphorylates rum1.|resulting-ptm:Phosphorylation of Rum1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/15 2014/10/16 rogid:66UWvndQ1xihZmi/pEZbhdSJsxg284812 rogid:Xm26f9FnmjG9I6P1hrk/9kWszzY284812 intact-crc:5835DF8B5AD02D9E|rigid:Ym0mpoTHu0K9ee1KhQ6zCROB+sQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)