#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39013 uniprotkb:P32521 intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C intact:EBI-12875|uniprotkb:D6VVT6|ensemblfungi:YIR006C psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:pan1_yeast(display_long)|uniprotkb:PAN1(gene name)|psi-mi:PAN1(display_short)|uniprotkb:MDP3(gene name synonym)|uniprotkb:MIP3(gene name synonym)|uniprotkb:YIR006C(locus name)|uniprotkb:YIB6C(orf name)|uniprotkb:DIM2(gene name synonym)|uniprotkb:Mitochondrial distribution of proteins protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tang et al. (1997) pubmed:9234686|imex:IM-19361 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1559443|imex:IM-19361-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 refseq:NP_012271.3|sgd:S000001445|interpro:IPR013182(Protein of unknown function DUF1720)|interpro:IPR018247|reactome:R-SCE-416482|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406|ensemblfungi:YIR006C(gene)|ensemblfungi:YIR006C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P32521|dip:DIP-1340N - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/28 2014/10/16 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 rogid:7T29adw2ZQua2jddwmvnnsQ9zq8559292 intact-crc:45F576600B74FE49|rigid:dcAcHThBQNVHONZG2dis58Qvn+E false - binding-associated region:1-849 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32521 uniprotkb:P39013 intact:EBI-12875|uniprotkb:D6VVT6|ensemblfungi:YIR006C intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C psi-mi:pan1_yeast(display_long)|uniprotkb:PAN1(gene name)|psi-mi:PAN1(display_short)|uniprotkb:MDP3(gene name synonym)|uniprotkb:MIP3(gene name synonym)|uniprotkb:YIR006C(locus name)|uniprotkb:YIB6C(orf name)|uniprotkb:DIM2(gene name synonym)|uniprotkb:Mitochondrial distribution of proteins protein 3(gene name synonym) psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tang et al. (1997) pubmed:9234686|imex:IM-19361 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1559472|imex:IM-19361-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012271.3|sgd:S000001445|interpro:IPR013182(Protein of unknown function DUF1720)|interpro:IPR018247|reactome:R-SCE-416482|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406|ensemblfungi:YIR006C(gene)|ensemblfungi:YIR006C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P32521|dip:DIP-1340N refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/28 2014/10/16 rogid:7T29adw2ZQua2jddwmvnnsQ9zq8559292 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 intact-crc:296B8A645BCA3FB0|rigid:dcAcHThBQNVHONZG2dis58Qvn+E false binding-associated region:1-849 binding-associated region:254-349 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32521 uniprotkb:P39013 intact:EBI-12875|uniprotkb:D6VVT6|ensemblfungi:YIR006C intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C psi-mi:pan1_yeast(display_long)|uniprotkb:PAN1(gene name)|psi-mi:PAN1(display_short)|uniprotkb:MDP3(gene name synonym)|uniprotkb:MIP3(gene name synonym)|uniprotkb:YIR006C(locus name)|uniprotkb:YIB6C(orf name)|uniprotkb:DIM2(gene name synonym)|uniprotkb:Mitochondrial distribution of proteins protein 3(gene name synonym) psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (1997) pubmed:9234686|imex:IM-19361 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1559511|imex:IM-19361-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012271.3|sgd:S000001445|interpro:IPR013182(Protein of unknown function DUF1720)|interpro:IPR018247|reactome:R-SCE-416482|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406|ensemblfungi:YIR006C(gene)|ensemblfungi:YIR006C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P32521|dip:DIP-1340N refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/28 2014/10/16 rogid:7T29adw2ZQua2jddwmvnnsQ9zq8559292 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 intact-crc:2EE0F388B42F800B|rigid:dcAcHThBQNVHONZG2dis58Qvn+E false ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32521 uniprotkb:P39013 intact:EBI-12875|uniprotkb:D6VVT6|ensemblfungi:YIR006C intact:EBI-6460|intact:EBI-33854|intact:EBI-30557|intact:EBI-31021|uniprotkb:D6W195|uniprotkb:Q8TFC4|uniprotkb:Q8TFD0|uniprotkb:Q8TG51|ensemblfungi:YNL084C psi-mi:pan1_yeast(display_long)|uniprotkb:PAN1(gene name)|psi-mi:PAN1(display_short)|uniprotkb:MDP3(gene name synonym)|uniprotkb:MIP3(gene name synonym)|uniprotkb:YIR006C(locus name)|uniprotkb:YIB6C(orf name)|uniprotkb:DIM2(gene name synonym)|uniprotkb:Mitochondrial distribution of proteins protein 3(gene name synonym) psi-mi:end3_yeast(display_long)|uniprotkb:END3(gene name)|psi-mi:END3(display_short)|uniprotkb:YNL084C(locus name)|uniprotkb:N2307(orf name)|uniprotkb:Endocytosis protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (1997) pubmed:9234686|imex:IM-19361 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1559526|imex:IM-19361-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012271.3|sgd:S000001445|interpro:IPR013182(Protein of unknown function DUF1720)|interpro:IPR018247|reactome:R-SCE-416482|reactome:R-SCE-8856825|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406|ensemblfungi:YIR006C(gene)|ensemblfungi:YIR006C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P32521|dip:DIP-1340N refseq:NP_014315.1|sgd:S000005028|mint:P39013|dip:DIP-2220N|ensemblfungi:YNL084C(gene)|ensemblfungi:YNL084C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0071944"(cell periphery)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR025604|reactome:R-SCE-416482|reactome:R-SCE-8856828|reactome:R-SCE-9013148|reactome:R-SCE-9013406 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/28 2014/10/16 rogid:7T29adw2ZQua2jddwmvnnsQ9zq8559292 rogid:AvVFZdzX/4DkLet/+FGA8KrKfCw559292 intact-crc:911B612F0A88DBF7|rigid:dcAcHThBQNVHONZG2dis58Qvn+E false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)